Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ABCA10	0	genome.wustl.edu	37	17	67178855	67178855	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	67178855	67178855	G	T	SNP	ABCA10	ENST00000269081	human	ensembl	74_37	-1	known	silent	c.2592	p.P864	0.000	NULL	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCA10	HGNC	ENSG00000154263	tier1	-	-	44	0	0.00	46	4	8.00
ABCC8	0	genome.wustl.edu	37	11	17449846	17449846	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	17449846	17449846	C	T	SNP	ABCC8	ENST00000302539	human	ensembl	74_37	-1	known	missense	c.2030	p.C677Y	0.490	NULL	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,prints_Sulphorea_rcpt,prints_Surea_rcpt-1,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom	-	no_errors	ABCC8	HGNC	ENSG00000006071	tier1	-	-	35	0	0.00	50	4	7.41
ABHD17A	0	genome.wustl.edu	37	19	1880936	1880936	+	Silent	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	1880936	1880936	T	C	SNP	ABHD17A	ENST00000250974	human	ensembl	74_37	-1	known	silent	c.444	p.T148	0.000	NULL	pfam_Dienelactn_hydro	-	no_errors	ABHD17A	HGNC	ENSG00000129968				115	0	0.00	61	4	6.15
ACADL	0	genome.wustl.edu	37	2	211085455	211085455	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	211085455	211085455	C	T	SNP	ACADL	ENST00000233710	human	ensembl	74_37	-1	known	missense	c.149	p.R50Q	1.000	superfamily_AcylCoA_DH/oxidase_NM_dom	pfam_AcylCo_DH/oxidase_C,pfam_AcylCoA_DH/ox_N,pfam_Acyl-CoA_Oxase/DH_cen-dom,pfam_Acyl-CoA_DH_2_C,superfamily_AcylCoA_DH/oxidase_NM_dom,superfamily_AcylCo_DH/oxidase_C	-	no_errors	ACADL	HGNC	ENSG00000115361	tier1	-	-	48	0	0.00	8	38	82.61
ADAMTS13	0	genome.wustl.edu	37	9	136290691	136290691	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	136290691	136290691	C	T	SNP	ADAMTS13	ENST00000371929	human	ensembl	74_37	+1	known	missense	c.373	p.R125W	1.000	pfam_Peptidase_M12B,pfscan_Peptidase_M12B	pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,superfamily_CUB_dom,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS13	HGNC	ENSG00000160323	tier1	-	-	43	0	0.00	27	31	53.45
ADAMTS2	0	genome.wustl.edu	37	5	178579173	178579173	+	Frame_Shift_Del	DEL	G	G	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	178579173	178579173	G	-	DEL	ADAMTS2	ENST00000251582	human	ensembl	74_37	-1	known	frame_shift_del	c.1599	p.L534fs	0.009	NULL	pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Pept_M12B_ADAM-TS2,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS2	HGNC	ENSG00000087116	tier1			64	0	0.00	37	2	5.13
AHNAK2	0	genome.wustl.edu	37	14	105409712	105409712	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	14	105409712	105409712	C	G	SNP	AHNAK2	ENST00000333244	human	ensembl	74_37	-1	known	missense	c.12076	p.E4026Q	0.000	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHNAK2	HGNC	ENSG00000185567	tier1	-	-	149	0	0.00	58	43	42.57
AKNA	0	genome.wustl.edu	37	9	117129824	117129824	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	117129824	117129824	T	A	SNP	AKNA	ENST00000307564	human	ensembl	74_37	-1	known	missense	c.1727	p.K576M	1.000	NULL	pfam_TF_AT-hook	-	no_errors	AKNA	HGNC	ENSG00000106948	tier1	-	-	44	0	0.00	23	3	11.54
ANAPC2	0	genome.wustl.edu	37	9	140074823	140074823	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	140074823	140074823	G	A	SNP	ANAPC2	ENST00000323927	human	ensembl	74_37	-1	known	missense	c.1700	p.S567F	0.998	pfam_Cullin_N,superfamily_Cullin_homology,smart_Cullin_homology,pfscan_Cullin_homology	pfam_Cullin_N,pfam_APC_su2_C,superfamily_Cullin_homology,smart_Cullin_homology,pfscan_Cullin_homology	-	no_errors	ANAPC2	HGNC	ENSG00000176248	tier1	-	-	69	0	0.00	62	11	15.07
ANK3	0	genome.wustl.edu	37	10	61835810	61835810	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	61835810	61835810	G	T	SNP	ANK3	ENST00000280772	human	ensembl	74_37	-1	known	missense	c.4829	p.P1610H	0.997	NULL	pfam_Ankyrin_rpt,pfam_ZU5,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,smart_ZU5,smart_Death_domain,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,pfscan_ZU5,prints_Ankyrin_rpt	-	no_errors	ANK3	HGNC	ENSG00000151150	tier1	-	-	55	0	0.00	52	4	7.14
ANKRD6	0	genome.wustl.edu	37	6	90334314	90334314	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	90334314	90334314	G	T	SNP	ANKRD6	ENST00000339746	human	ensembl	74_37	+1	known	missense	c.1275	p.L425F	1.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD6	HGNC	ENSG00000135299				87	0	0.00	66	4	5.71
AP5Z1	0	genome.wustl.edu	37	7	4824612	4824612	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	4824612	4824612	G	A	SNP	AP5Z1	ENST00000348624	human	ensembl	74_37	+1	known	silent	c.864	p.P288	0.997	NULL	NULL	-	no_errors	AP5Z1	HGNC	ENSG00000242802	tier1	-	-	67	0	0.00	57	28	32.18
APOC3	0	genome.wustl.edu	37	11	116703493	116703493	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	116703493	116703493	G	A	SNP	APOC3	ENST00000227667	human	ensembl	74_37	+1	known	missense	c.193	p.D65N	0.000	pfam_Apo-CIII	pfam_Apo-CIII	-	no_errors	APOC3	HGNC	ENSG00000110245	tier1	rs149707394	-	97	0	0.00	67	24	26.37
AQP7	0	genome.wustl.edu	37	9	33386447	33386447	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	33386447	33386447	G	T	SNP	AQP7	ENST00000297988	human	ensembl	74_37	-1	known	missense	c.361	p.L121M	0.999	pfam_MIP,superfamily_Aquaporin-like,prints_MIP,tigrfam_MIP	pfam_MIP,superfamily_Aquaporin-like,prints_MIP,prints_Aquaporin_3,tigrfam_MIP	-	no_errors	AQP7	HGNC	ENSG00000165269	tier1	-	-	237	0	0.00	167	22	11.64
ARFGAP2	0	genome.wustl.edu	37	11	47189519	47189519	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	47189519	47189519	G	T	SNP	ARFGAP2	ENST00000524782	human	ensembl	74_37	-1	known	missense	c.1146	p.D382E	1.000	NULL	pfam_ArfGAP,smart_ArfGAP,pfscan_ArfGAP,prints_ArfGAP	-	no_errors	ARFGAP2	HGNC	ENSG00000149182	tier1	-	-	72	0	0.00	43	4	8.51
ARHGEF15	0	genome.wustl.edu	37	17	8221919	8221919	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	8221919	8221919	G	A	SNP	ARHGEF15	ENST00000361926	human	ensembl	74_37	+1	known	missense	c.1811	p.R604H	1.000	superfamily_DH-domain	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,pfscan_DH-domain	-	no_errors	ARHGEF15	HGNC	ENSG00000198844				51	0	0.00	23	2	8.00
ARSI	0	genome.wustl.edu	37	5	149676934	149676934	+	Frame_Shift_Del	DEL	C	C	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	149676934	149676934	C	0	DEL	ARSI	ENST00000328668	human	ensembl	74_37	-1	known	frame_shift_del	c.1553	p.G518fs	1.000	superfamily_Alkaline_phosphatase_core	pfam_Sulfatase,superfamily_Alkaline_phosphatase_core	-	no_errors	ARSI	HGNC	ENSG00000183876				38	0	0.00	28	10	26.32
ATAT1	0	genome.wustl.edu	37	6	30594688	30594688	+	Missense_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	30594688	30594688	C	A	SNP	ATAT1	ENST00000376485	human	ensembl	74_37	+1	known	missense	c.26	p.A9E	0.998	NULL	pfam_Alpha-TAT,superfamily_Acyl_CoA_acyltransferase	-	no_errors	ATAT1	HGNC	ENSG00000137343	tier1	-	-	123	0	0.00	79	24	23.08
ATM	0	genome.wustl.edu	37	11	108137916	108137916	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	108137916	108137916	C	T	SNP	ATM	ENST00000278616	human	ensembl	74_37	+1	known	missense	c.2485	p.P829S	1.000	superfamily_ARM-type_fold	pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_TAN,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom	-	no_errors	ATM	HGNC	ENSG00000149311	tier1	-	-	50	0	0.00	63	4	5.97
ATN1	0	genome.wustl.edu	37	12	7044758	7044758	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	7044758	7044758	G	A	SNP	ATN1	ENST00000356654	human	ensembl	74_37	+1	known	missense	c.328	p.G110R	1.000	pfam_Atrophin-like	pfam_Atrophin-like,prints_Atrophin-1	-	no_errors	ATN1	HGNC	ENSG00000111676	tier1	-	-	82	0	0.00	55	14	20.29
BDH2	0	genome.wustl.edu	37	4	104000908	104000908	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	104000908	104000908	G	A	SNP	BDH2	ENST00000296424	human	ensembl	74_37	-1	known	missense	c.689	p.A230V	1.000	prints_DHB_DH	pfam_DH_sc/Rdtase_SDR,prints_Glc/ribitol_DH,prints_DHB_DH,prints_DH_sc/Rdtase_SDR,prints_ADH_insect	-	no_errors	BDH2	HGNC	ENSG00000164039				65	0	0.00	35	2	5.41
BPIFA1	0	genome.wustl.edu	37	20	31825905	31825905	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	31825905	31825905	G	C	SNP	BPIFA1	ENST00000354297	human	ensembl	74_37	+1	known	missense	c.205	p.E69Q	0.001	pfam_Lipid-bd_serum_glycop_N	pfam_Lipid-bd_serum_glycop_N,superfamily_Bactericidal_perm-incr_a/b_dom	-	no_errors	BPIFA1	HGNC	ENSG00000198183	tier1	-	-	57	0	0.00	58	28	32.56
BRD4	0	genome.wustl.edu	37	19	15375435	15375435	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	15375435	15375435	G	T	SNP	BRD4	ENST00000263377	human	ensembl	74_37	-1	known	missense	c.992	p.P331Q	1.000	superfamily_Bromodomain	pfam_Bromodomain,superfamily_Bromodomain,smart_Bromodomain,pfscan_Bromodomain,prints_Bromodomain	-	no_errors	BRD4	HGNC	ENSG00000141867				80	0	0.00	36	2	5.26
C16orf78	0	genome.wustl.edu	37	16	49407973	49407973	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	49407973	49407973	G	T	SNP	C16orf78	ENST00000299191	human	ensembl	74_37	+1	known	missense	c.123	p.R41S	0.985	NULL	NULL	-	no_errors	C16orf78	HGNC	ENSG00000166152				63	0	0.00	55	3	5.17
C16orf89	0	genome.wustl.edu	37	16	5105319	5105319	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	5105319	5105319	A	C	SNP	C16orf89	ENST00000350219	human	ensembl	74_37	-1	known	missense	c.910	p.F304V	1.000	NULL	NULL	-	no_errors	C16orf89	HGNC	ENSG00000153446	tier1	-	-	63	0	0.00	42	16	27.59
C21orf58	0	genome.wustl.edu	37	21	47721986	47721988	+	In_Frame_Del	DEL	TGG	TGG	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	TGG	TGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	21	47721986	47721988	TGG	-	DEL	C21orf58	ENST00000291691	human	ensembl	74_37	-1	known	in_frame_del	c.896_894	p.H299in_frame_del	0.001:0.001:0.001	NULL	NULL	-	no_errors	C21orf58	HGNC	ENSG00000160298	tier1			36	0	0.00	33	2	5.71
C2orf68	0	genome.wustl.edu	37	2	85838932	85838932	+	Nonstop_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	85838932	85838932	C	A	SNP	C2orf68	ENST00000423181	human	ensembl	74_37	-1	known	nonstop	c.176	p.*59L	1.000	NULL	pfam_UPF0561	-	no_errors	C2orf68	HGNC	ENSG00000168887	tier1	-	-	39	0	0.00	41	18	30.51
C6orf211	0	genome.wustl.edu	37	6	151773812	151773812	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	151773812	151773812	G	A	SNP	C6orf211	ENST00000483931	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	C6orf211	HGNC	ENSG00000146476	tier1	-	-	87	0	0.00	68	4	5.56
CAB39	0	genome.wustl.edu	37	2	231657972	231657972	+	Silent	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	231657972	231657972	A	G	SNP	CAB39	ENST00000258418	human	ensembl	74_37	+1	known	silent	c.324	p.R108	1.000	pfam_Mo25,superfamily_ARM-type_fold	pfam_Mo25,superfamily_ARM-type_fold	-	no_errors	CAB39	HGNC	ENSG00000135932	tier1	-	-	57	0	0.00	52	15	22.39
CACNA1A	0	genome.wustl.edu	37	19	13616887	13616887	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	13616887	13616887	G	T	SNP	CACNA1A	ENST00000360228	human	ensembl	74_37	-1	known	nonsense	c.152	p.S51*	0.996	NULL	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCCAlpha1,prints_VDCC_P/Q_a1su	-	no_errors	CACNA1A	HGNC	ENSG00000141837				44	0	0.00	31	2	6.06
CAMK1D	0	genome.wustl.edu	37	10	12391792	12391792	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	12391792	12391792	G	A	SNP	CAMK1D	ENST00000487696	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	CAMK1D	HGNC	ENSG00000183049	tier1	-	-	61	0	0.00	21	31	59.62
CCDC115	0	genome.wustl.edu	37	2	131097207	131097207	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	131097207	131097207	C	G	SNP	CCDC115	ENST00000442217	human	ensembl	74_37	-1	known	missense	c.559	p.E187Q	0.001	NULL	NULL	-	no_errors	CCDC115	HGNC	ENSG00000136710	tier1	-	-	31	0	0.00	16	23	58.97
CCDC132	0	genome.wustl.edu	37	7	92970741	92970741	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	92970741	92970741	A	C	SNP	CCDC132	ENST00000305866	human	ensembl	74_37	+1	known	missense	c.2061	p.E687D	1.000	NULL	pfam_Vacuolar_sorting-assoc_54,pfam_DUF2451_C	-	no_errors	CCDC132	HGNC	ENSG00000004766	tier1	-	-	68	0	0.00	62	13	17.33
CCDC147	0	genome.wustl.edu	37	10	106139896	106139896	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	106139896	106139896	C	T	SNP	CCDC147	ENST00000369704	human	ensembl	74_37	+1	known	missense	c.1283	p.A428V	1.000	NULL	superfamily_Homeodomain-like	-	no_errors	CCDC147	HGNC	ENSG00000120051				57	0	0.00	73	4	5.13
CCDC74A	0	genome.wustl.edu	37	2	132290352	132290352	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	132290352	132290352	G	C	SNP	CCDC74A	ENST00000295171	human	ensembl	74_37	+1	known	missense	c.874	p.E292Q	1.000	NULL	NULL	-	no_errors	CCDC74A	HGNC	ENSG00000163040	tier1	-	-	125	0	0.00	87	53	37.86
CD96	0	genome.wustl.edu	37	3	111298030	111298031	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	AG	AG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	111298030	111298031	AG	-	DEL	CD96	ENST00000283285	human	ensembl	74_37	+1	known	frame_shift_del	c.748_749	p.R250fs	0.000:0.000	smart_Ig_sub	smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	CD96	HGNC	ENSG00000153283	tier1			89	0	0.00	77	36	31.86
CDK11B	0	genome.wustl.edu	37	1	1581180	1581180	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	1581180	1581180	G	C	SNP	CDK11B	ENST00000407249	human	ensembl	74_37	-1	known	missense	c.344	p.T115R	0.028	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK11B	HGNC	ENSG00000248333	tier1	-	-	364	0	0.00	284	43	13.15
CDK13	0	genome.wustl.edu	37	7	40027419	40027419	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	40027419	40027419	A	C	SNP	CDK13	ENST00000181839	human	ensembl	74_37	+1	known	missense	c.1433	p.K478T	0.989	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK13	HGNC	ENSG00000065883	tier1	-	-	27	0	0.00	20	12	37.50
CDKN2A	0	genome.wustl.edu	37	9	21974766	21974766	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	21974766	21974766	C	T	SNP	CDKN2A	ENST00000446177	human	ensembl	74_37	-1	known	missense	c.61	p.A21T	0.925	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	CDKN2A	HGNC	ENSG00000147889				45	0	0.00	17	2	10.53
CHRM1	0	genome.wustl.edu	37	11	62677888	62677888	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	62677888	62677888	C	T	SNP	CHRM1	ENST00000306960	human	ensembl	74_37	-1	known	missense	c.685	p.E229K	0.966	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Musac_Ach_M1_rcpt,prints_Musac_Ach_rcpt,prints_GPCR_Rhodpsn	-	no_errors	CHRM1	HGNC	ENSG00000168539	tier1	-	-	36	0	0.00	16	18	52.94
CLMN	0	genome.wustl.edu	37	14	95669921	95669921	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	14	95669921	95669921	T	C	SNP	CLMN	ENST00000298912	human	ensembl	74_37	-1	known	missense	c.1765	p.T589A	0.000	NULL	pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	CLMN	HGNC	ENSG00000165959				97	0	0.00	58	4	6.45
CLYBL	0	genome.wustl.edu	37	13	100511232	100511232	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	13	100511232	100511232	C	G	SNP	CLYBL	ENST00000339105	human	ensembl	74_37	+1	known	missense	c.367	p.L123V	0.964	pfam_Aldehyde-lyase_domain,superfamily_Pyrv/PenolPyrv_Kinase-like_dom,pirsf_Citrate_lyase_beta	pfam_Aldehyde-lyase_domain,superfamily_Pyrv/PenolPyrv_Kinase-like_dom,pirsf_Citrate_lyase_beta	-	no_errors	CLYBL	HGNC	ENSG00000125246	tier1	-	-	95	0	0.00	17	41	70.69
CNKSR2	0	genome.wustl.edu	37	X	21534649	21534649	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	21534649	21534649	C	G	SNP	CNKSR2	ENST00000379510	human	ensembl	74_37	+1	known	missense	c.857	p.P286R	1.000	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	pfam_CNKSR2,pfam_CRIC_domain_Chordata,pfam_SAM_type1,pfam_Pleckstrin_homology,pfam_SAM_2,pfam_PDZ,superfamily_SAM/pointed,superfamily_PDZ,smart_SAM,smart_PDZ,smart_Pleckstrin_homology,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_SAM	-	no_errors	CNKSR2	HGNC	ENSG00000149970	tier1	-	-	75	0	0.00	15	57	79.17
COL9A1	0	genome.wustl.edu	37	6	70970365	70970365	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	70970365	70970365	C	T	SNP	COL9A1	ENST00000357250	human	ensembl	74_37	-1	known	missense	c.1444	p.E482K	0.981	pfam_Collagen	pfam_Collagen,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G	-	no_errors	COL9A1	HGNC	ENSG00000112280	tier1	-	-	86	0	0.00	49	26	34.21
COQ10B	0	genome.wustl.edu	37	2	198318574	198318574	+	RNA	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	198318574	198318574	C	G	SNP	COQ10B	ENST00000488445	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	COQ10B	HGNC	ENSG00000115520	tier1	-	-	68	0	0.00	40	14	25.93
CPNE4	0	genome.wustl.edu	37	3	131253640	131253640	+	RNA	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	131253640	131253640	G	T	SNP	CPNE4	ENST00000503204	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CPNE4	HGNC	ENSG00000196353	tier1	-	-	73	0	0.00	58	4	6.45
CSF2RA	0	genome.wustl.edu	37	X	1407924	1407924	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	1407924	1407924	G	A	SNP	CSF2RA	ENST00000478256	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.005	-	-	-	no_errors	CSF2RA	HGNC	ENSG00000198223	tier1	-	-	8	0	0.00	8	5	38.46
CTDSPL2	0	genome.wustl.edu	37	15	44751267	44751267	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	44751267	44751267	C	T	SNP	CTDSPL2	ENST00000260327	human	ensembl	74_37	+1	known	missense	c.55	p.R19C	1.000	NULL	pfam_NIF,superfamily_HAD-like_dom,smart_NIF,pfscan_NIF,tigrfam_Dullard_phosphatase	-	no_errors	CTDSPL2	HGNC	ENSG00000137770	tier1	-	-	60	0	0.00	65	15	18.75
CXCR2	0	genome.wustl.edu	37	2	219000352	219000352	+	Silent	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	219000352	219000352	C	A	SNP	CXCR2	ENST00000318507	human	ensembl	74_37	+1	known	silent	c.828	p.L276	0.994	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Chemokine_CXCR_1/2	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Chemokine_CXCR_1/2,prints_GPCR_Rhodpsn,prints_Chemokine_CXCR2,prints_Chemokine_rcpt,prints_Chemokine_CXCR4	-	no_errors	CXCR2	HGNC	ENSG00000180871	tier1	-	-	32	0	0.00	62	11	15.07
DACT3	0	genome.wustl.edu	37	19	47152183	47152183	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	47152183	47152183	G	A	SNP	DACT3	ENST00000391916	human	ensembl	74_37	-1	known	silent	c.1446	p.I482	1.000	NULL	NULL	-	no_errors	DACT3	HGNC	ENSG00000197380	tier1	-	-	9	0	0.00	0	5	100.00
DMXL1	0	genome.wustl.edu	37	5	118482976	118482976	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	118482976	118482976	G	A	SNP	DMXL1	ENST00000539542	human	ensembl	74_37	+1	known	missense	c.2722	p.V908I	0.757	superfamily_WD40_repeat_dom	pfam_Rav1p_C,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DMXL1	HGNC	ENSG00000172869	tier1	-	-	79	0	0.00	34	12	26.09
DNAH1	0	genome.wustl.edu	37	3	52428676	52428676	+	Silent	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	52428676	52428676	C	A	SNP	DNAH1	ENST00000420323	human	ensembl	74_37	+1	known	silent	c.10822	p.R3608	1.000	pfam_Dynein_heavy_dom	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase	-	no_errors	DNAH1	HGNC	ENSG00000114841				62	0	0.00	34	2	5.56
DNAH2	0	genome.wustl.edu	37	17	7643207	7643207	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	7643207	7643207	G	T	SNP	DNAH2	ENST00000389173	human	ensembl	74_37	+1	known	missense	c.1327	p.G443W	0.823	pfam_Dynein_heavy_dom-1	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_Dynein_heavy_dom-1,pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA_core,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH2	HGNC	ENSG00000183914				42	0	0.00	30	3	8.82
DOK5	0	genome.wustl.edu	37	20	53205284	53205284	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	53205284	53205284	C	T	SNP	DOK5	ENST00000262593	human	ensembl	74_37	+1	known	silent	c.348	p.I116	1.000	NULL	pfam_Insln_rcpt_S1,pfam_Pleckstrin_homology,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Insln_rcpt_S1	-	no_errors	DOK5	HGNC	ENSG00000101134	tier1	-	-	77	0	0.00	50	43	46.24
DST	0	genome.wustl.edu	37	6	56374518	56374518	+	Silent	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	56374518	56374518	A	G	SNP	DST	ENST00000370754	human	ensembl	74_37	-1	known	silent	c.18841	p.L6281	0.050	superfamily_ABC1_TM_dom,smart_Spectrin/alpha-actinin	pfam_Spectrin_repeat,pfam_Plectin_repeat,pfam_CH-domain,pfam_GAS2_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_GAS2_dom,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Plectin_repeat,smart_EF_hand_dom,smart_GAS2_dom,pfscan_CH-domain,pfscan_EF_hand_dom	-	no_errors	DST	HGNC	ENSG00000151914	tier1	-	-	58	0	0.00	39	16	29.09
EFNA2	0	genome.wustl.edu	37	19	1295853	1295853	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	1295853	1295853	C	T	SNP	EFNA2	ENST00000215368	human	ensembl	74_37	+1	known	silent	c.450	p.Y150	1.000	pfam_Ephrin,superfamily_Cupredoxin	pfam_Ephrin,superfamily_Cupredoxin,prints_Ephrin	-	no_errors	EFNA2	HGNC	ENSG00000099617	tier1	-	-	51	0	0.00	43	4	8.51
ENSG00000232600	0	genome.wustl.edu	37	8	145662361	145662361	+	RNA	DEL	C	C	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	145662361	145662361	C	-	DEL	ENSG00000232600	ENST00000544423	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC084125.4	Clone_based_vega_gene	ENSG00000232600	tier1			68	0	0.00	98	15	13.27
ENSG00000255366	0	genome.wustl.edu	37	8	48104491	48104491	+	RNA	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	48104491	48104491	G	T	SNP	ENSG00000255366	ENST00000528139	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-1134I14.8	Clone_based_vega_gene	ENSG00000255366				27	0	0.00	17	4	19.05
ENSG00000267688	0	genome.wustl.edu	37	19	3122087	3122087	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	3122087	3122087	G	A	SNP	ENSG00000267688	ENST00000585980	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC005262.2	Clone_based_vega_gene	ENSG00000267688	tier1	-	-	57	0	0.00	33	4	10.53
EPHA2	0	genome.wustl.edu	37	1	16464434	16464434	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	16464434	16464434	G	T	SNP	EPHA2	ENST00000358432	human	ensembl	74_37	-1	known	missense	c.1226	p.T409N	1.000	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom	-	no_errors	EPHA2	HGNC	ENSG00000142627	tier1	-	-	75	0	0.00	66	4	5.71
ESPNL	0	genome.wustl.edu	37	2	239025586	239025586	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	239025586	239025586	C	T	SNP	ESPNL	ENST00000343063	human	ensembl	74_37	+1	known	missense	c.898	p.R300W	0.600	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ESPNL	HGNC	ENSG00000144488				68	0	0.00	52	3	5.45
ESYT3	0	genome.wustl.edu	37	3	138178065	138178065	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	138178065	138178065	G	T	SNP	ESYT3	ENST00000389567	human	ensembl	74_37	+1	known	missense	c.618	p.Q206H	1.000	NULL	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,prints_C2_dom,pfscan_C2_dom	-	no_errors	ESYT3	HGNC	ENSG00000158220	tier1	-	-	58	0	0.00	43	4	8.51
EXD3	0	genome.wustl.edu	37	9	140287583	140287583	+	Frame_Shift_Del	DEL	G	G	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	140287583	140287583	G	0	DEL	EXD3	ENST00000465160	human	ensembl	74_37	-1	putative	frame_shift_del	c.160	p.L54fs	0.996	NULL	NULL	-	no_errors	EXD3	HGNC	ENSG00000187609				44	0	0.00	35	8	18.60
FAM120A	0	genome.wustl.edu	37	9	96278385	96278385	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	96278385	96278385	T	C	SNP	FAM120A	ENST00000333936	human	ensembl	74_37	+1	known	missense	c.1252	p.Y418H	1.000	NULL	NULL	-	no_errors	FAM120A	HGNC	ENSG00000048828	tier1	rs138573585	-	54	0	0.00	29	4	12.12
FAM171A1	0	genome.wustl.edu	37	10	15255663	15255663	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	15255663	15255663	C	T	SNP	FAM171A1	ENST00000378116	human	ensembl	74_37	-1	known	missense	c.1924	p.A642T	1.000	pfam_Uncharacterised_FAM171	pfam_Uncharacterised_FAM171	-	no_errors	FAM171A1	HGNC	ENSG00000148468				59	0	0.00	31	2	6.06
FAM178B	0	genome.wustl.edu	37	2	97595017	97595017	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	97595017	97595017	G	T	SNP	FAM178B	ENST00000417561	human	ensembl	74_37	-1	known	silent	c.1563	p.V521	0.359	NULL	NULL	-	no_errors	FAM178B	HGNC	ENSG00000168754				76	0	0.00	63	4	5.97
FAM188B	0	genome.wustl.edu	37	7	30893033	30893033	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	30893033	30893033	C	T	SNP	FAM188B	ENST00000265299	human	ensembl	74_37	+1	known	silent	c.1635	p.C545	0.996	NULL	NULL	-	no_errors	FAM188B	HGNC	ENSG00000106125				49	0	0.00	71	4	5.33
FAM86C2P	0	genome.wustl.edu	37	11	67560294	67560294	+	RNA	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	67560294	67560294	A	G	SNP	FAM86C2P	ENST00000528089	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.010	-	-	-	no_errors	FAM86C2P	HGNC	ENSG00000160172				26	0	0.00	37	4	9.76
FBXW7	0	genome.wustl.edu	37	4	153332739	153332739	+	Nonsense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	153332739	153332739	G	A	SNP	FBXW7	ENST00000281708	human	ensembl	74_37	-1	known	nonsense	c.217	p.Q73*	1.000	NULL	pfam_WD40_repeat,pfam_F-box_dom,superfamily_WD40_repeat_dom,superfamily_F-box_dom,smart_F-box_dom,smart_WD40_repeat,pfscan_F-box_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	FBXW7	HGNC	ENSG00000109670	tier1	-	-	68	0	0.00	15	38	71.70
FMOD	0	genome.wustl.edu	37	1	203316579	203316579	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	203316579	203316579	G	A	SNP	FMOD	ENST00000354955	human	ensembl	74_37	-1	known	missense	c.820	p.R274W	0.996	NULL	pfam_Leu-rich_rpt,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	FMOD	HGNC	ENSG00000122176	tier1	rs200924838	-	62	0	0.00	47	4	7.84
FOLR3	0	genome.wustl.edu	37	11	71847080	71847080	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	71847080	71847080	C	T	SNP	FOLR3	ENST00000456237	human	ensembl	74_37	+1	known	missense	c.82	p.R28W	0.000	NULL	pfam_Folate_rcpt-like	-	no_errors	FOLR3	HGNC	ENSG00000110203	tier1	-	-	50	0	0.00	47	10	17.54
FOXP2	0	genome.wustl.edu	37	7	114271582	114271582	+	Splice_Site	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	114271582	114271582	G	C	SNP	FOXP2	ENST00000408937	human	ensembl	74_37	+1	known	splice_site	c.673-1	e6-1	0.135	-	-	-	no_errors	FOXP2	HGNC	ENSG00000128573				40	0	0.00	29	2	6.45
FPGT-TNNI3K	0	genome.wustl.edu	37	1	74819805	74819805	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	74819805	74819805	A	G	SNP	FPGT-TNNI3K	ENST00000557284	human	ensembl	74_37	+1	known	missense	c.1511	p.Y504C	1.000	superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom,prints_Ankyrin_rpt,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	FPGT-TNNI3K	HGNC	ENSG00000259030	tier1	-	-	44	0	0.00	34	11	24.44
FREM2	0	genome.wustl.edu	37	13	39264040	39264040	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	13	39264040	39264040	C	T	SNP	FREM2	ENST00000280481	human	ensembl	74_37	+1	known	silent	c.2559	p.H853	1.000	NULL	pfam_Calx_beta,superfamily_Cadherin-like,smart_Calx_beta	-	no_errors	FREM2	HGNC	ENSG00000150893	tier1	-	-	50	0	0.00	22	12	35.29
FREM3	0	genome.wustl.edu	37	4	144617840	144617840	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	144617840	144617840	A	C	SNP	FREM3	ENST00000329798	human	ensembl	74_37	-1	putative	missense	c.3989	p.L1330R	0.985	NULL	pfam_Calx_beta,superfamily_Cadherin-like,smart_Calx_beta	-	no_errors	FREM3	HGNC	ENSG00000183090	tier1	-	-	74	0	0.00	30	12	28.57
FUK	0	genome.wustl.edu	37	16	70501800	70501800	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	70501800	70501800	G	T	SNP	FUK	ENST00000378912	human	ensembl	74_37	+1	known	missense	c.690	p.L230F	0.975	pfam_Fucokinase	pfam_Fucokinase,pfam_GHMP_kinase_C_dom,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_Trimer_LpxA-like,prints_Galkinase	-	no_errors	FUK	HGNC	ENSG00000157353	tier1	-	-	100	0	0.00	46	4	8.00
FYB	0	genome.wustl.edu	37	5	39202766	39202766	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	39202766	39202766	G	T	SNP	FYB	ENST00000540520	human	ensembl	74_37	-1	known	silent	c.327	p.T109	0.000	NULL	pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain	-	no_errors	FYB	HGNC	ENSG00000082074	tier1	-	-	85	0	0.00	60	4	6.25
GEMIN4	0	genome.wustl.edu	37	17	650493	650493	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	650493	650493	C	T	SNP	GEMIN4	ENST00000319004	human	ensembl	74_37	-1	known	missense	c.790	p.V264M	0.000	NULL	NULL	-	no_errors	GEMIN4	HGNC	ENSG00000179409				34	0	0.00	16	3	15.79
GFM1	0	genome.wustl.edu	37	3	158408049	158408049	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	158408049	158408049	C	T	SNP	GFM1	ENST00000486715	human	ensembl	74_37	+1	known	silent	c.2007	p.N669	1.000	pfam_EFG_V,superfamily_EFG_III-V,smart_EFG_V,tigrfam_Transl_elong_EFG/EF2	pfam_EF_GTP-bd_dom,pfam_Transl_elong_EFG/EF2_IV,pfam_EFG_V,pfam_Transl_elong_EFTu/EF1A_2,superfamily_P-loop_NTPase,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_Transl_B-barrel,superfamily_EFG_III-V,smart_Transl_elong_EFG/EF2_IV,smart_EFG_V,prints_EF_GTP-bd_dom,tigrfam_Transl_elong_EFG/EF2,tigrfam_Small_GTP-bd_dom	-	no_errors	GFM1	HGNC	ENSG00000168827				97	0	0.00	72	4	5.26
GGN	0	genome.wustl.edu	37	19	38877720	38877720	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	38877720	38877720	A	G	SNP	GGN	ENST00000334928	human	ensembl	74_37	-1	known	missense	c.182	p.M61T	0.935	NULL	NULL	-	no_errors	GGN	HGNC	ENSG00000179168	tier1	-	-	77	0	0.00	64	30	31.58
GGT7	0	genome.wustl.edu	37	20	33440292	33440292	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	33440292	33440292	C	T	SNP	GGT7	ENST00000336431	human	ensembl	74_37	-1	novel	missense	c.1369	p.A457T	0.104	pfam_GGT_peptidase	pfam_GGT_peptidase,prints_GGT_peptidase	-	no_errors	GGT7	HGNC	ENSG00000131067	tier1	-	-	66	0	0.00	70	13	15.66
GJD2	0	genome.wustl.edu	37	15	35045307	35045307	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	35045307	35045307	A	G	SNP	GJD2	ENST00000290374	human	ensembl	74_37	-1	known	missense	c.338	p.F113S	1.000	NULL	pfam_Connexin_N,pfam_Connexin_CCC,smart_Connexin_N,prints_Connexin,prints_Connexin36	-	no_errors	GJD2	HGNC	ENSG00000159248	tier1	-	-	61	0	0.00	41	31	43.06
GPR112	0	genome.wustl.edu	37	X	135430821	135430821	+	Silent	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	135430821	135430821	T	G	SNP	GPR112	ENST00000370652	human	ensembl	74_37	+1	known	silent	c.4956	p.T1652	0.000	NULL	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	GPR112	HGNC	ENSG00000156920	tier1	-	-	19	0	0.00	14	10	41.67
GPR112	0	genome.wustl.edu	37	X	135445724	135445724	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	135445724	135445724	G	T	SNP	GPR112	ENST00000370652	human	ensembl	74_37	+1	known	missense	c.7366	p.V2456L	1.000	NULL	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Pentaxin,superfamily_ConA-like_lec_gl_sf,smart_Pentaxin,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	GPR112	HGNC	ENSG00000156920	tier1	-	-	30	0	0.00	28	4	12.50
GRAMD1C	0	genome.wustl.edu	37	3	113619948	113619948	+	Missense_Mutation	SNP	A	A	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	113619948	113619948	A	T	SNP	GRAMD1C	ENST00000358160	human	ensembl	74_37	+1	known	missense	c.611	p.E204V	1.000	NULL	pfam_GRAM,smart_GRAM	-	no_errors	GRAMD1C	HGNC	ENSG00000178075	tier1	-	-	58	0	0.00	47	16	25.40
GRIN3B	0	genome.wustl.edu	37	19	1005120	1005120	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	1005120	1005120	G	T	SNP	GRIN3B	ENST00000234389	human	ensembl	74_37	+1	known	missense	c.1620	p.Q540H	0.660	pfam_SBP_bac_3,smart_Iontro_glu_rcpt	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN3B	HGNC	ENSG00000116032				49	0	0.00	33	2	5.71
GRM8	0	genome.wustl.edu	37	7	126173499	126173499	+	Missense_Mutation	SNP	A	A	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	126173499	126173499	A	T	SNP	GRM8	ENST00000339582	human	ensembl	74_37	-1	known	missense	c.1937	p.I646N	0.995	pfam_GPCR_3_C,pfscan_GPCR_3_C	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,prints_GPCR_3,prints_GPCR_3_mtglu_rcpt_8,prints_GPCR_3_mtglu_rcpt,prints_GPCR_3_mtglu_rcpt_4,pfscan_GPCR_3_C	-	no_errors	GRM8	HGNC	ENSG00000179603	tier1	-	-	46	0	0.00	13	18	58.06
GYG2P1	0	genome.wustl.edu	37	Y	14495005	14495005	+	RNA	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	Y	14495005	14495005	C	G	SNP	GYG2P1	ENST00000493160	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.995	-	-	-	no_errors	GYG2P1	HGNC	ENSG00000206159	tier1	-	-	22	0	0.00	27	4	12.90
HACE1	0	genome.wustl.edu	37	6	105177430	105177430	+	RNA	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	105177430	105177430	C	T	SNP	HACE1	ENST00000517995	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	HACE1	HGNC	ENSG00000085382	tier1	-	-	13	0	0.00	6	7	53.85
HAL	0	genome.wustl.edu	37	12	96379931	96379931	+	Silent	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	96379931	96379931	A	G	SNP	HAL	ENST00000261208	human	ensembl	74_37	-1	known	silent	c.1059	p.H353	0.994	pfam_Aromatic_Lyase,superfamily_L-Aspartase-like,tigrfam_HutH	pfam_Aromatic_Lyase,superfamily_L-Aspartase-like,tigrfam_HutH	-	no_errors	HAL	HGNC	ENSG00000084110	tier1	-	-	43	0	0.00	32	17	34.69
HCN2	0	genome.wustl.edu	37	19	603569	603569	+	Missense_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	603569	603569	C	A	SNP	HCN2	ENST00000251287	human	ensembl	74_37	+1	known	missense	c.658	p.L220M	1.000	pfam_Ion_trans_N	pfam_Ion_trans_N,pfam_cNMP-bd_dom,pfam_Ion_trans_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG/ELK/ERG	-	no_errors	HCN2	HGNC	ENSG00000099822				47	0	0.00	26	2	7.14
HERPUD1	0	genome.wustl.edu	37	16	56973168	56973168	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	56973168	56973168	G	A	SNP	HERPUD1	ENST00000439977	human	ensembl	74_37	+1	known	missense	c.451	p.A151T	0.959	NULL	pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup	-	no_errors	HERPUD1	HGNC	ENSG00000051108	tier1	-	-	93	0	0.00	59	4	6.35
HK1	0	genome.wustl.edu	37	10	71148995	71148995	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	71148995	71148995	G	T	SNP	HK1	ENST00000448642	human	ensembl	74_37	+1	known	missense	c.2083	p.G695C	1.000	pfam_Hexokinase_N,prints_Hexokinase	pfam_Hexokinase_C,pfam_Hexokinase_N,prints_Hexokinase	-	no_errors	HK1	HGNC	ENSG00000156515	tier1	-	-	70	0	0.00	57	4	6.56
HLA-DPA1	0	genome.wustl.edu	37	6	33037071	33037071	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	33037071	33037071	G	C	SNP	HLA-DPA1	ENST00000419277	human	ensembl	74_37	-1	known	missense	c.353	p.P118R	0.997	pfscan_Ig-like_dom	pfam_MHC_II_a_N,pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_MHC_II_a_N,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	HLA-DPA1	HGNC	ENSG00000231389	tier1	-	-	54	0	0.00	32	11	25.58
HNF4A	0	genome.wustl.edu	37	20	43030116	43030116	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	43030116	43030116	C	T	SNP	HNF4A	ENST00000316099	human	ensembl	74_37	+1	known	missense	c.104	p.T35M	1.000	NULL	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_COUP_TF,prints_Retinoid-X_rcpt/HNF4	-	no_errors	HNF4A	HGNC	ENSG00000101076				59	0	0.00	53	3	5.36
HPS3	0	genome.wustl.edu	37	3	148877872	148877872	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	148877872	148877872	G	T	SNP	HPS3	ENST00000296051	human	ensembl	74_37	+1	known	nonsense	c.1912	p.E638*	1.000	pirsf_HPS3	pirsf_HPS3	-	no_errors	HPS3	HGNC	ENSG00000163755	tier1	-	-	80	0	0.00	52	4	7.14
HRC	0	genome.wustl.edu	37	19	49657890	49657892	+	In_Frame_Del	DEL	TCC	TCC	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	TCC	TCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	49657890	49657892	TCC	-	DEL	HRC	ENST00000252825	human	ensembl	74_37	-1	known	in_frame_del	c.605_603	p.E204in_frame_del	0.004:0.016:0.003	NULL	pfam_Hist_rich_Ca-bd	-	no_errors	HRC	HGNC	ENSG00000130528	tier1			36	0	0.00	32	3	8.57
HTR3B	0	genome.wustl.edu	37	11	113803807	113803807	+	Nonsense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	113803807	113803807	C	T	SNP	HTR3B	ENST00000260191	human	ensembl	74_37	+1	known	nonsense	c.688	p.Q230*	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_5HT3_rcpt_B,prints_5HT3_rcpt,prints_Neur_channel,prints_5HT3_rcpt_A,tigrfam_Neur_channel	-	no_errors	HTR3B	HGNC	ENSG00000149305	tier1	-	-	75	0	0.00	58	16	21.62
ID1	0	genome.wustl.edu	37	20	30193543	30193543	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	30193543	30193543	C	T	SNP	ID1	ENST00000376112	human	ensembl	74_37	+1	known	missense	c.353	p.P118L	1.000	superfamily_bHLH_dom	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	ID1	HGNC	ENSG00000125968	tier1	rs200577120	-	47	0	0.00	30	29	49.15
IGSF10	0	genome.wustl.edu	37	3	151155705	151155705	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	151155705	151155705	G	A	SNP	IGSF10	ENST00000282466	human	ensembl	74_37	-1	known	missense	c.6644	p.A2215V	1.000	pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	IGSF10	HGNC	ENSG00000152580				68	0	0.00	52	3	5.45
IL27RA	0	genome.wustl.edu	37	19	14160008	14160008	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	14160008	14160008	C	T	SNP	IL27RA	ENST00000263379	human	ensembl	74_37	+1	known	silent	c.1284	p.A428	0.000	superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL27RA	HGNC	ENSG00000104998	tier1	-	-	62	0	0.00	28	10	26.32
INTS1	0	genome.wustl.edu	37	7	1536943	1536943	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	1536943	1536943	G	A	SNP	INTS1	ENST00000389470	human	ensembl	74_37	-1	known	missense	c.1817	p.A606V	1.000	NULL	pfam_DUF3677,superfamily_ARM-type_fold	-	no_errors	INTS1	HGNC	ENSG00000164880	tier1	-	-	25	0	0.00	26	12	31.58
ITGA4	0	genome.wustl.edu	37	2	182363438	182363438	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	182363438	182363438	G	T	SNP	ITGA4	ENST00000397033	human	ensembl	74_37	+1	known	silent	c.1629	p.V543	0.367	pfam_Integrin_alpha-2	pfam_Integrin_alpha-2,pfam_FG-GAP,smart_Int_alpha_beta-p,prints_Integrin_alpha	-	no_errors	ITGA4	HGNC	ENSG00000115232	tier1	-	-	52	0	0.00	63	4	5.97
ITM2B	0	genome.wustl.edu	37	13	48807528	48807528	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	13	48807528	48807528	C	T	SNP	ITM2B	ENST00000378565	human	ensembl	74_37	+1	known	missense	c.32	p.A11V	1.000	NULL	pfam_BRICHOS_dom,pfscan_BRICHOS_dom	-	no_errors	ITM2B	HGNC	ENSG00000136156	tier1	-	-	70	0	0.00	43	4	8.51
ITPR2	0	genome.wustl.edu	37	12	26750058	26750058	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	26750058	26750058	C	T	SNP	ITPR2	ENST00000381340	human	ensembl	74_37	-1	known	missense	c.4012	p.G1338R	0.996	pfam_Ca-rel_channel,superfamily_ARM-type_fold	pfam_Ca-rel_channel,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ARM-type_fold,smart_MIR_motif,prints_InsP3_rcpt-bd,pfscan_MIR_motif	-	no_errors	ITPR2	HGNC	ENSG00000123104				59	0	0.00	36	2	5.26
IVL	0	genome.wustl.edu	37	1	152882812	152882812	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	152882812	152882812	A	G	SNP	IVL	ENST00000368764	human	ensembl	74_37	+1	known	missense	c.539	p.E180G	0.003	pfam_Involucrin_rpt	pfam_Involucrin_N,pfam_Involucrin_rpt	-	no_errors	IVL	HGNC	ENSG00000163207	tier1	-	-	118	0	0.00	86	33	27.73
KAT6B	0	genome.wustl.edu	37	10	76735386	76735386	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	76735386	76735386	A	C	SNP	KAT6B	ENST00000287239	human	ensembl	74_37	+1	known	missense	c.1291	p.T431P	1.000	NULL	pfam_MOZ_SAS,pfam_Znf_PHD-finger,pfam_Histone_H1/H5_H15,superfamily_Acyl_CoA_acyltransferase,superfamily_Znf_FYVE_PHD,smart_Histone_H1/H5_H15,smart_Znf_PHD,pfscan_Znf_PHD-finger	-	no_errors	KAT6B	HGNC	ENSG00000156650	tier1	-	-	77	0	0.00	57	16	21.92
KCNA5	0	genome.wustl.edu	37	12	5153505	5153505	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	5153505	5153505	G	A	SNP	KCNA5	ENST00000252321	human	ensembl	74_37	+1	known	silent	c.192	p.V64	0.000	prints_K_chnl_volt-dep_Kv1.5	pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,pfam_PKD1_2_channel,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv1.5,prints_K_chnl_volt-dep_Kv1,prints_K_chnl_volt-dep_Kv	-	no_errors	KCNA5	HGNC	ENSG00000130037	tier1	-	-	30	0	0.00	13	11	45.83
KCND2	0	genome.wustl.edu	37	7	119915600	119915600	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	119915600	119915600	G	T	SNP	KCND2	ENST00000331113	human	ensembl	74_37	+1	known	missense	c.914	p.R305L	1.000	pfam_Ion_trans_dom,prints_K_chnl,prints_K_chnl_volt-dep_Kv	pfam_K_chnl_volt-dep_Kv4_C,pfam_T1-type_BTB,pfam_Ion_trans_dom,pfam_Shal-type,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv4,prints_K_chnl_volt-dep_Kv4.2,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv3	-	no_errors	KCND2	HGNC	ENSG00000184408				56	0	0.00	41	3	6.67
KCNT2	0	genome.wustl.edu	37	1	196459055	196459055	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	196459055	196459055	C	T	SNP	KCNT2	ENST00000294725	human	ensembl	74_37	-1	known	missense	c.188	p.R63H	1.000	NULL	pfam_K_chnl_Ca-activ_BK_asu,pfam_2pore_dom_K_chnl_dom	-	no_errors	KCNT2	HGNC	ENSG00000162687				35	0	0.00	34	2	5.41
KDM2A	0	genome.wustl.edu	37	11	67024132	67024132	+	RNA	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	67024132	67024132	C	T	SNP	KDM2A	ENST00000524657	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.737	-	-	-	no_errors	KDM2A	HGNC	ENSG00000173120	tier1	-	-	52	0	0.00	36	16	30.77
KDM4C	0	genome.wustl.edu	37	9	6805609	6805609	+	Missense_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	6805609	6805609	C	A	SNP	KDM4C	ENST00000381309	human	ensembl	74_37	+1	known	missense	c.155	p.P52H	1.000	smart_TF_JmjN,pfscan_TF_JmjN	pfam_JmjC_dom,pfam_TF_JmjN,superfamily_Znf_FYVE_PHD,superfamily_Chorismate_mutase_type_II,smart_TF_JmjN,smart_JmjC_dom,smart_Znf_PHD,smart_Tudor,pfscan_TF_JmjN,pfscan_JmjC_dom	-	no_errors	KDM4C	HGNC	ENSG00000107077				28	0	0.00	25	2	7.41
KHDRBS3	0	genome.wustl.edu	37	8	136533590	136533590	+	Missense_Mutation	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	136533590	136533590	T	G	SNP	KHDRBS3	ENST00000355849	human	ensembl	74_37	+1	known	missense	c.199	p.F67V	1.000	smart_KH_dom	smart_KH_dom	-	no_errors	KHDRBS3	HGNC	ENSG00000131773	tier1	-	-	60	0	0.00	36	10	21.74
KIAA1429	0	genome.wustl.edu	37	8	95538801	95538801	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	95538801	95538801	G	A	SNP	KIAA1429	ENST00000297591	human	ensembl	74_37	-1	known	silent	c.1671	p.C557	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	KIAA1429	HGNC	ENSG00000164944				55	0	0.00	56	3	5.08
KIAA1551	0	genome.wustl.edu	37	12	32135664	32135664	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	32135664	32135664	G	A	SNP	KIAA1551	ENST00000312561	human	ensembl	74_37	+1	known	missense	c.1775	p.R592H	0.000	NULL	NULL	-	no_errors	KIAA1551	HGNC	ENSG00000174718	tier1	-	-	65	0	0.00	20	3	13.04
KIF1A	0	genome.wustl.edu	37	2	241725750	241725750	+	Splice_Site	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	241725750	241725750	A	C	SNP	KIF1A	ENST00000498729	human	ensembl	74_37	-1	known	splice_site	c.608+2	e5+2	0.992	-	-	-	no_errors	KIF1A	HGNC	ENSG00000130294	tier1	-	-	62	0	0.00	58	5	7.94
KMT2D	0	genome.wustl.edu	37	12	49422664	49422664	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	49422664	49422664	C	T	SNP	KMT2D	ENST00000301067	human	ensembl	74_37	-1	known	missense	c.14329	p.G4777S	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2D	HGNC	ENSG00000167548	tier1	-	-	31	0	0.00	38	4	9.52
KRTAP11-1	0	genome.wustl.edu	37	21	32253808	32253808	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	21	32253808	32253808	G	A	SNP	KRTAP11-1	ENST00000332378	human	ensembl	74_37	-1	known	silent	c.36	p.S12	0.991	pfam_KRTAP_PMG	pfam_KRTAP_PMG	-	no_errors	KRTAP11-1	HGNC	ENSG00000182591	tier1	-	-	38	0	0.00	24	10	29.41
LAMB1	0	genome.wustl.edu	37	7	107569652	107569652	+	Splice_Site	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	107569652	107569652	T	G	SNP	LAMB1	ENST00000222399	human	ensembl	74_37	-1	known	splice_site	c.4746-2	e30-2	1.000	-	-	-	no_errors	LAMB1	HGNC	ENSG00000091136	tier1	-	-	83	0	0.00	14	45	76.27
LINC00588	0	genome.wustl.edu	37	8	58196770	58196770	+	RNA	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	58196770	58196770	T	C	SNP	LINC00588	ENST00000521663	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.977	-	-	-	no_errors	LINC00588	HGNC	ENSG00000215117	tier1	-	-	24	0	0.00	10	9	47.37
LOC101928414	0	genome.wustl.edu	37	15	45545880	45545881	+	RNA	INS	-	-	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	45545880	45545881	-	A	INS	LOC101928414	ENST00000560344	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.073:0.086	-	-	-	no_errors	CTD-2651B20.3	Clone_based_vega_gene	ENSG00000259520	tier1			17	0	0.00	18	4	18.18
LPCAT4	0	genome.wustl.edu	37	15	34655019	34655019	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	34655019	34655019	G	A	SNP	LPCAT4	ENST00000314891	human	ensembl	74_37	-1	known	silent	c.765	p.L255	1.000	NULL	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase	-	no_errors	LPCAT4	HGNC	ENSG00000176454	tier1	-	-	41	0	0.00	51	22	30.14
LPCAT4	0	genome.wustl.edu	37	15	34656266	34656266	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	34656266	34656266	G	C	SNP	LPCAT4	ENST00000314891	human	ensembl	74_37	-1	known	missense	c.600	p.F200L	0.999	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase	-	no_errors	LPCAT4	HGNC	ENSG00000176454	tier1	-	-	60	0	0.00	62	37	37.37
LRRC16A	0	genome.wustl.edu	37	6	25488781	25488781	+	Missense_Mutation	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	25488781	25488781	T	G	SNP	LRRC16A	ENST00000329474	human	ensembl	74_37	+1	novel	missense	c.1033	p.S345A	1.000	smart_Leu-rich_rpt_RNase_inh_sub-typ	smart_Leu-rich_rpt_RNase_inh_sub-typ	-	no_errors	LRRC16A	HGNC	ENSG00000079691	tier1	-	-	98	0	0.00	44	27	38.03
LRRC4B	0	genome.wustl.edu	37	19	51022077	51022077	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	51022077	51022077	G	A	SNP	LRRC4B	ENST00000389201	human	ensembl	74_37	-1	known	missense	c.893	p.T298M	1.000	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LRRC4B	HGNC	ENSG00000131409	tier1	-	-	85	0	0.00	46	32	41.03
LRRC53	0	genome.wustl.edu	37	1	74941009	74941009	+	Missense_Mutation	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	74941009	74941009	T	G	SNP	LRRC53	ENST00000294635	human	ensembl	74_37	-1	novel	missense	c.1390	p.T464P	0.003	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC53	HGNC	ENSG00000162621	tier1	-	-	60	0	0.00	41	10	19.61
LRRIQ1	0	genome.wustl.edu	37	12	85517975	85517975	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	85517975	85517975	G	T	SNP	LRRIQ1	ENST00000393217	human	ensembl	74_37	+1	known	nonsense	c.3685	p.E1229*	0.210	NULL	pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_IQ_motif_EF-hand-BS,smart_Leu-rich_rpt_typical-subtyp,pfscan_IQ_motif_EF-hand-BS	-	no_errors	LRRIQ1	HGNC	ENSG00000133640	tier1	-	-	52	0	0.00	19	3	12.50
LRRK2	0	genome.wustl.edu	37	12	40631771	40631771	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	40631771	40631771	G	A	SNP	LRRK2	ENST00000298910	human	ensembl	74_37	+1	known	missense	c.437	p.G146D	1.000	superfamily_ARM-type_fold	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_MIRO-like,pfam_Small_GTPase,pfam_Leu-rich_rpt,pfam_Small_GTPase_ARF/SAR,superfamily_Kinase-like_dom,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,superfamily_WD40_repeat_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Small_GTPase_Rab_type,smart_Tyr_kinase_cat_dom,smart_Ser/Thr_dual-sp_kinase_dom,prints_Small_GTPase,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,tigrfam_Small_GTP-bd_dom	-	no_errors	LRRK2	HGNC	ENSG00000188906				71	0	0.00	43	3	6.52
LTBP1	0	genome.wustl.edu	37	2	33482427	33482427	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	33482427	33482427	C	G	SNP	LTBP1	ENST00000354476	human	ensembl	74_37	+1	known	missense	c.2244	p.H748Q	1.000	NULL	pfam_EGF-like_Ca-bd_dom,pfam_TB_dom,pfam_EG-like_dom,superfamily_TB_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	LTBP1	HGNC	ENSG00000049323	tier1	-	-	88	0	0.00	41	44	51.76
MAGEB4	0	genome.wustl.edu	37	X	30261121	30261121	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	30261121	30261121	C	T	SNP	MAGEB4	ENST00000378982	human	ensembl	74_37	+1	known	missense	c.869	p.A290V	0.001	pfscan_MAGE	pfam_MAGE,pfam_Melanoma_ass_antigen_N,pfscan_MAGE	-	no_errors	MAGEB4	HGNC	ENSG00000120289	tier1	-	-	39	0	0.00	44	4	8.33
METTL14	0	genome.wustl.edu	37	4	119609098	119609098	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	119609098	119609098	C	T	SNP	METTL14	ENST00000388822	human	ensembl	74_37	+1	known	silent	c.87	p.D29	1.000	NULL	pfam_MT-A70-like,pfscan_MT-A70-like	-	no_errors	METTL14	HGNC	ENSG00000145388	tier1	-	-	62	0	0.00	39	4	9.30
METTL25	0	genome.wustl.edu	37	12	82796879	82796879	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	82796879	82796879	T	A	SNP	METTL25	ENST00000248306	human	ensembl	74_37	+1	known	missense	c.1249	p.L417I	1.000	NULL	NULL	-	no_errors	METTL25	HGNC	ENSG00000127720	tier1	-	-	69	0	0.00	42	17	28.81
MIR22HG	0	genome.wustl.edu	37	17	1617203	1617203	+	RNA	DEL	G	G	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	1617203	1617203	G	-	DEL	MIR22HG	ENST00000334146	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	MIR22HG	HGNC	ENSG00000186594	tier1			57	0	0.00	19	2	9.52
MKLN1	0	genome.wustl.edu	37	7	131149111	131149111	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	131149111	131149111	G	T	SNP	MKLN1	ENST00000352689	human	ensembl	74_37	+1	known	nonsense	c.1732	p.E578*	1.000	NULL	pfam_Muskelin_N,pfam_Kelch_1,pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_LisH_dimerisation,pfscan_LisH_dimerisation,pfscan_CTLH_C	-	no_errors	MKLN1	HGNC	ENSG00000128585	tier1	-	-	60	0	0.00	58	4	6.45
MS4A12	0	genome.wustl.edu	37	11	60264806	60264806	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	60264806	60264806	G	T	SNP	MS4A12	ENST00000016913	human	ensembl	74_37	+1	known	missense	c.15	p.K5N	0.002	NULL	pfam_CD20-like	-	no_errors	MS4A12	HGNC	ENSG00000071203				72	0	0.00	67	4	5.63
MT-RNR1	0	genome.wustl.edu	37	MT	1509	1509	+	RNA	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	MT	1509	1509	T	A	SNP	MT-RNR1	ENST00000389680	human	ensembl	74_37	+1	known	rna	NULL	NULL	NULL	-	-	-	no_errors	MT-RNR1	HGNC	ENSG00000211459	tier1	-	-	28	0	0.00	5	2	28.57
MT-RNR2	0	genome.wustl.edu	37	MT	1732	1732	+	RNA	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	MT	1732	1732	C	T	SNP	MT-RNR2	ENST00000387347	human	ensembl	74_37	+1	known	rna	NULL	NULL	NULL	-	-	-	no_errors	MT-RNR2	HGNC	ENSG00000210082	tier1	-	-	51	0	0.00	6	2	25.00
MTMR9	0	genome.wustl.edu	37	8	11180257	11180257	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	11180257	11180257	C	T	SNP	MTMR9	ENST00000221086	human	ensembl	74_37	+1	known	missense	c.1610	p.A537V	1.000	NULL	pfam_Myotubularin-like_Pase_dom	-	no_errors	MTMR9	HGNC	ENSG00000104643	tier1	-	-	61	0	0.00	47	4	7.84
MUC5B	0	genome.wustl.edu	37	11	1263020	1263020	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	1263020	1263020	C	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	missense	c.4919	p.P1640L	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	52	0	0.00	20	27	57.45
MUC5B	0	genome.wustl.edu	37	11	1269837	1269837	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	1269837	1269837	C	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.11736	p.V3912	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	209	0	0.00	147	95	39.26
MVB12B	0	genome.wustl.edu	37	9	129268626	129268626	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	129268626	129268626	G	A	SNP	MVB12B	ENST00000485886	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	MVB12B	HGNC	ENSG00000196814	tier1	-	-	35	0	0.00	22	4	15.38
MYH9	0	genome.wustl.edu	37	22	36685195	36685195	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	22	36685195	36685195	A	C	SNP	MYH9	ENST00000216181	human	ensembl	74_37	-1	known	missense	c.4493	p.L1498R	1.000	pfam_Myosin_tail,superfamily_Prefoldin	pfam_Myosin_head_motor_dom,pfam_Myosin_tail,pfam_Myosin_N,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_Regulat_G_prot_signal_superfam,superfamily_Prefoldin,superfamily_Myosin_S1_N,superfamily_STAT_TF_coiled-coil,superfamily_tRNA-bd_arm,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYH9	HGNC	ENSG00000100345	tier1	-	-	33	0	0.00	7	16	69.57
MYO6	0	genome.wustl.edu	37	6	76602272	76602272	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	76602272	76602272	G	A	SNP	MYO6	ENST00000369981	human	ensembl	74_37	+1	known	missense	c.2972	p.R991Q	0.011	NULL	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO6	HGNC	ENSG00000196586	tier1	-	-	73	0	0.00	62	4	6.06
MYT1	0	genome.wustl.edu	37	20	62839660	62839660	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	62839660	62839660	G	T	SNP	MYT1	ENST00000536311	human	ensembl	74_37	+1	known	missense	c.1111	p.D371Y	1.000	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1	HGNC	ENSG00000196132	tier1	-	-	34	0	0.00	29	12	29.27
NANOS2	0	genome.wustl.edu	37	19	46417601	46417601	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	46417601	46417601	G	A	SNP	NANOS2	ENST00000341294	human	ensembl	74_37	-1	known	silent	c.351	p.N117	0.268	NULL	pfam_Znf_nanos-typ	-	no_errors	NANOS2	HGNC	ENSG00000188425	tier1	-	-	113	0	0.00	100	181	64.18
NARF	0	genome.wustl.edu	37	17	80417920	80417920	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	80417920	80417920	C	T	SNP	NARF	ENST00000309794	human	ensembl	74_37	+1	known	missense	c.80	p.A27V	0.000	NULL	pfam_Fe_hydrogenase_lsu_C,pfam_Fe_hydrogenase_ssu-like,superfamily_Fe_hydrogenase,smart_Fe_hydrogenase_ssu-like	-	no_errors	NARF	HGNC	ENSG00000141562	tier1	-	-	75	0	0.00	48	4	7.69
NCOA1	0	genome.wustl.edu	37	2	24974968	24974968	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	24974968	24974968	C	T	SNP	NCOA1	ENST00000348332	human	ensembl	74_37	+1	known	missense	c.3824	p.S1275F	0.990	pirsf_Nuclear_rcpt_coactivator	pfam_DUF1518,pfam_SRC-1,pfam_Nuc_rcpt_coact_Ncoa-typ,pfam_PAS_fold,superfamily_PAS,superfamily_Nuc_rcpt_coact,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,pirsf_Nuclear_rcpt_coactivator,pfscan_PAS,pfscan_bHLH_dom	-	no_errors	NCOA1	HGNC	ENSG00000084676	tier1	-	-	45	0	0.00	40	25	38.46
NELFCD	0	genome.wustl.edu	37	20	57569723	57569723	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	57569723	57569723	G	T	SNP	NELFCD	ENST00000602795	human	ensembl	74_37	+1	known	missense	c.1792	p.V598L	1.000	pfam_TH1	pfam_TH1	-	no_errors	NELFCD	HGNC	ENSG00000101158	tier1	-	-	91	0	0.00	51	36	41.38
NKX6-3	0	genome.wustl.edu	37	8	41505662	41505662	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	41505662	41505662	C	G	SNP	NKX6-3	ENST00000518699	human	ensembl	74_37	-1	known	missense	c.475	p.E159Q	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_HTH_motif,prints_Homeobox_metazoa	-	no_errors	NKX6-3	HGNC	ENSG00000165066	tier1	-	-	72	0	0.00	37	25	40.32
NLRP12	0	genome.wustl.edu	37	19	54312916	54312916	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	54312916	54312916	T	A	SNP	NLRP12	ENST00000324134	human	ensembl	74_37	-1	known	missense	c.1997	p.Y666F	0.000	NULL	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_NACHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP12	HGNC	ENSG00000142405	tier1	-	-	50	0	0.00	29	20	40.82
NMNAT1	0	genome.wustl.edu	37	1	10035755	10035755	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	10035755	10035755	C	G	SNP	NMNAT1	ENST00000377205	human	ensembl	74_37	+1	known	missense	c.221	p.T74S	1.000	pfam_Cyt_trans-like,tigrfam_NAMN_adtrnsfrase	pfam_Cyt_trans-like,tigrfam_NAMN_adtrnsfrase	-	no_errors	NMNAT1	HGNC	ENSG00000173614	tier1	-	-	79	0	0.00	53	19	26.39
NOA1	0	genome.wustl.edu	37	4	57842621	57842621	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	57842621	57842621	G	T	SNP	NOA1	ENST00000264230	human	ensembl	74_37	-1	known	silent	c.1131	p.I377	1.000	superfamily_P-loop_NTPase	superfamily_P-loop_NTPase	-	no_errors	NOA1	HGNC	ENSG00000084092	tier1	-	-	19	0	0.00	8	12	60.00
NOTCH1	0	genome.wustl.edu	37	9	139397714	139397714	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	139397714	139397714	G	A	SNP	NOTCH1	ENST00000277541	human	ensembl	74_37	-1	known	missense	c.5087	p.A1696V	1.000	pfam_Notch_NODP_dom,pirsf_Notch	pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,pfam_Ankyrin_rpt,pfam_EGF_extracell,pfam_Notch_NOD_dom,pfam_DUF3454_notch,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,pirsf_Notch,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom,prints_Notch_1,prints_Notch_dom	-	no_errors	NOTCH1	HGNC	ENSG00000148400	tier1	-	-	65	0	0.00	36	7	16.28
NR1H2	0	genome.wustl.edu	37	19	50885724	50885724	+	Silent	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	50885724	50885724	C	G	SNP	NR1H2	ENST00000253727	human	ensembl	74_37	+1	known	silent	c.1248	p.R416	1.000	pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Liver_X_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Ecdystd_rcpt,prints_ThyrH_rcpt	-	no_errors	NR1H2	HGNC	ENSG00000131408	tier1	-	-	31	0	0.00	29	13	30.95
NUB1	0	genome.wustl.edu	37	7	151042544	151042544	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	151042544	151042544	G	A	SNP	NUB1	ENST00000568733	human	ensembl	74_37	+1	known	missense	c.181	p.A61T	1.000	NULL	pfam_UBA/Ts_N,superfamily_UBA-like,smart_UBA/transl_elong_EF1B_N_euk,pfscan_UBA/transl_elong_EF1B_N_euk	-	no_errors	NUB1	HGNC	ENSG00000013374				66	0	0.00	72	4	5.19
NUDT14	0	genome.wustl.edu	37	14	105639420	105639420	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	14	105639420	105639420	C	T	SNP	NUDT14	ENST00000392568	human	ensembl	74_37	-1	known	missense	c.607	p.G203S	0.975	superfamily_NUDIX_hydrolase_dom-like,tigrfam_NDP_pyrophosphatase	pfam_NUDIX_hydrolase_dom,superfamily_NUDIX_hydrolase_dom-like,tigrfam_NDP_pyrophosphatase	-	no_errors	NUDT14	HGNC	ENSG00000183828	tier1	-	-	31	0	0.00	3	16	84.21
NUP188	0	genome.wustl.edu	37	9	131767801	131767801	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	131767801	131767801	C	T	SNP	NUP188	ENST00000372577	human	ensembl	74_37	+1	known	silent	c.4729	p.L1577	0.997	NULL	pfam_Nucleoporin_Nup188,superfamily_ARM-type_fold	-	no_errors	NUP188	HGNC	ENSG00000095319	tier1	-	-	26	0	0.00	23	4	14.81
NUP210	0	genome.wustl.edu	37	3	13368884	13368884	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	13368884	13368884	C	T	SNP	NUP210	ENST00000254508	human	ensembl	74_37	-1	known	missense	c.4340	p.R1447H	0.987	NULL	pfam_Big_2,superfamily_Invasin/intimin_cell_adhesion,superfamily_Cadherin-like,smart_Big_2	-	no_errors	NUP210	HGNC	ENSG00000132182	tier1	-	-	33	0	0.00	51	4	7.27
NUP43	0	genome.wustl.edu	37	6	150070753	150070753	+	RNA	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	150070753	150070753	G	C	SNP	NUP43	ENST00000463048	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	NUP43	HGNC	ENSG00000120253	tier1	-	-	15	0	0.00	9	6	40.00
OPCML	0	genome.wustl.edu	37	11	132527063	132527063	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	132527063	132527063	C	G	SNP	OPCML	ENST00000541867	human	ensembl	74_37	-1	known	missense	c.319	p.V107L	0.994	pfam_Ig_I-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	OPCML	HGNC	ENSG00000183715	tier1	-	-	68	0	0.00	47	14	22.95
OR2A1	0	genome.wustl.edu	37	7	144015712	144015712	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	144015712	144015712	G	T	SNP	OR2A1	ENST00000408951	human	ensembl	74_37	+1	known	silent	c.495	p.L165	0.823	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2A1	HGNC	ENSG00000221970	tier1	-	-	21	0	0.00	15	7	31.82
OR2V1	0	genome.wustl.edu	37	5	180551778	180551778	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	180551778	180551778	T	C	SNP	OR2V1	ENST00000329365	human	ensembl	74_37	-1	known	missense	c.527	p.D176G	0.007	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR2V1	HGNC	ENSG00000185372	tier1	-	-	32	0	0.00	28	5	15.15
OTOF	0	genome.wustl.edu	37	2	26703132	26703132	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	26703132	26703132	C	T	SNP	OTOF	ENST00000272371	human	ensembl	74_37	-1	known	silent	c.1851	p.L617	1.000	NULL	pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	OTOF	HGNC	ENSG00000115155	tier1	-	-	60	0	0.00	83	9	9.78
P2RY1	0	genome.wustl.edu	37	3	152554373	152554373	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	152554373	152554373	G	T	SNP	P2RY1	ENST00000305097	human	ensembl	74_37	+1	known	missense	c.802	p.V268F	0.999	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_P2Y1_rcpt,prints_GPCR_Rhodpsn	-	no_errors	P2RY1	HGNC	ENSG00000169860				37	0	0.00	37	2	5.13
P2RY6	0	genome.wustl.edu	37	11	73007861	73007861	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	73007861	73007861	C	T	SNP	P2RY6	ENST00000349767	human	ensembl	74_37	+1	known	missense	c.298	p.R100C	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_P2Y6_rcpt,prints_GPCR_Rhodpsn,prints_P2Y3_rcpt,prints_Protea_act_rcpt	-	no_errors	P2RY6	HGNC	ENSG00000171631	tier1	-	-	50	0	0.00	27	19	41.30
PAK1	0	genome.wustl.edu	37	11	77034400	77034400	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	77034400	77034400	T	A	SNP	PAK1	ENST00000278568	human	ensembl	74_37	-1	known	missense	c.1606	p.I536F	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_CRIB_dom,superfamily_Kinase-like_dom,superfamily_WASP_C,smart_CRIB_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_CRIB_dom,pfscan_Prot_kinase_dom	-	no_errors	PAK1	HGNC	ENSG00000149269	tier1	-	-	56	0	0.00	44	4	8.33
PCDH10	0	genome.wustl.edu	37	4	134072935	134072935	+	Missense_Mutation	SNP	A	A	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	134072935	134072935	A	T	SNP	PCDH10	ENST00000264360	human	ensembl	74_37	+1	known	missense	c.1640	p.D547V	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH10	HGNC	ENSG00000138650	tier1	-	-	12	0	0.00	6	4	40.00
PCDH15	0	genome.wustl.edu	37	10	55973754	55973754	+	Missense_Mutation	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	55973754	55973754	A	C	SNP	PCDH15	ENST00000320301	human	ensembl	74_37	-1	known	missense	c.1040	p.L347R	1.000	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH15	HGNC	ENSG00000150275	tier1	-	-	39	0	0.00	18	25	58.14
PCDHGB7	0	genome.wustl.edu	37	5	140798869	140798869	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	140798869	140798869	C	T	SNP	PCDHGB7	ENST00000398594	human	ensembl	74_37	+1	known	silent	c.1443	p.F481	0.012	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHGB7	HGNC	ENSG00000254122				53	0	0.00	38	2	5.00
PER2	0	genome.wustl.edu	37	2	239185809	239185809	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	239185809	239185809	C	T	SNP	PER2	ENST00000254657	human	ensembl	74_37	-1	known	missense	c.256	p.A86T	0.323	NULL	pfam_Period_circadian-like_C,pfam_PAS_fold_3,pfam_PAS_fold,superfamily_PAS,smart_PAS,pfscan_PAS	-	no_errors	PER2	HGNC	ENSG00000132326	tier1	-	-	65	0	0.00	64	4	5.88
PFKFB1	0	genome.wustl.edu	37	X	54982677	54982677	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	54982677	54982677	C	T	SNP	PFKFB1	ENST00000375006	human	ensembl	74_37	-1	known	missense	c.547	p.D183N	0.991	pfam_6Phosfructo_kin,superfamily_P-loop_NTPase,pirsf_Bifunct_6PFK/fruc_bisP_Ptase,prints_6Pfruct_kin	pfam_6Phosfructo_kin,pfam_His_Pase_superF_clade-1,pfam_Zeta_toxin_domain,superfamily_P-loop_NTPase,smart_His_Pase_superF_clade-1,pirsf_Bifunct_6PFK/fruc_bisP_Ptase,prints_6Pfruct_kin	-	no_errors	PFKFB1	HGNC	ENSG00000158571	tier1	-	-	36	0	0.00	3	12	80.00
PHGR1	0	genome.wustl.edu	37	15	40648331	40648331	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	40648331	40648331	G	C	SNP	PHGR1	ENST00000448599	human	ensembl	74_37	+1	known	missense	c.76	p.G26R	0.006	NULL	NULL	-	no_errors	PHGR1	HGNC	ENSG00000233041				16	0	0.00	35	6	14.63
PICALM	0	genome.wustl.edu	37	11	85722153	85722153	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	85722153	85722153	G	T	SNP	PICALM	ENST00000393346	human	ensembl	74_37	-1	known	missense	c.685	p.Q229K	1.000	pfam_ANTH_dom	pfam_ANTH_dom,pfam_Epsin_dom_N,superfamily_ENTH_VHS,smart_Epsin-like_N,pfscan_Epsin-like_N	-	no_errors	PICALM	HGNC	ENSG00000073921				40	0	0.00	34	2	5.56
PICK1	0	genome.wustl.edu	37	22	38471034	38471036	+	In_Frame_Del	DEL	GGA	GGA	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	GGA	GGA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	22	38471034	38471036	GGA	-	DEL	PICK1	ENST00000356976	human	ensembl	74_37	+1	known	in_frame_del	c.1143_1145	p.E385in_frame_del	0.071:1.000:1.000	NULL	pfam_AH_dom,pfam_PDZ,pfam_BAR_dom,superfamily_PDZ,smart_PDZ,pfscan_AH_dom,pfscan_PDZ	-	no_errors	PICK1	HGNC	ENSG00000100151	tier1			29	0	0.00	20	2	9.09
PIRT	0	genome.wustl.edu	37	17	10728672	10728672	+	Silent	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	10728672	10728672	C	A	SNP	PIRT	ENST00000580256	human	ensembl	74_37	-1	known	silent	c.291	p.L97	1.000	NULL	NULL	-	no_errors	PIRT	HGNC	ENSG00000233670	tier1	-	-	82	0	0.00	25	21	45.65
PKDCC	0	genome.wustl.edu	37	2	42285285	42285285	+	RNA	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	42285285	42285285	C	G	SNP	PKDCC	ENST00000480099	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	PKDCC	HGNC	ENSG00000162878	tier1	-	-	66	0	0.00	56	15	21.13
PKLR	0	genome.wustl.edu	37	1	155260412	155260412	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	155260412	155260412	C	T	SNP	PKLR	ENST00000342741	human	ensembl	74_37	-1	known	missense	c.1676	p.R559Q	1.000	pfam_Pyrv_Knase_C,superfamily_Pyrv_Knase_C,tigrfam_Pyr_Knase	pfam_Pyrv_Knase_brl,pfam_Pyrv_Knase_C,superfamily_Pyrv/PenolPyrv_Kinase-like_dom,superfamily_Pyrv_Knase_C,superfamily_Pyrv_Knase-like_insert_dom,prints_Pyr_Knase,tigrfam_Pyr_Knase	-	no_errors	PKLR	HGNC	ENSG00000143627	tier1	-	-	55	0	0.00	53	13	19.70
PLOD1	0	genome.wustl.edu	37	1	12014761	12014761	+	RNA	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	12014761	12014761	C	T	SNP	PLOD1	ENST00000358133	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PLOD1	HGNC	ENSG00000083444	tier1	-	-	51	0	0.00	23	32	58.18
PLOD2	0	genome.wustl.edu	37	3	145841106	145841106	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	145841106	145841106	C	T	SNP	PLOD2	ENST00000480704	human	ensembl	74_37	-1	known	missense	c.208	p.G70R	0.000	NULL	NULL	-	no_errors	PLOD2	HGNC	ENSG00000152952	tier1	-	-	111	0	0.00	75	29	27.88
POTEE	0	genome.wustl.edu	37	2	132021884	132021884	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	132021884	132021884	C	T	SNP	POTEE	ENST00000356920	human	ensembl	74_37	+1	known	silent	c.2856	p.N952	1.000	pfam_Actin-related,smart_Actin-related,prints_Actin-related	pfam_Actin-related,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-related,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-related	-	no_errors	POTEE	HGNC	ENSG00000188219	tier1	-	-	157	0	0.00	113	33	22.60
PPOX	0	genome.wustl.edu	37	1	161137901	161137901	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	161137901	161137901	G	A	SNP	PPOX	ENST00000352210	human	ensembl	74_37	+1	known	missense	c.455	p.R152H	1.000	pfam_Amino_oxidase,tigrfam_Protoporphyrinogen_oxidase	pfam_Amino_oxidase,tigrfam_Protoporphyrinogen_oxidase	-	no_errors	PPOX	HGNC	ENSG00000143224	tier1	-	-	55	0	0.00	50	9	15.00
PPP1R26	0	genome.wustl.edu	37	9	138379218	138379218	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	138379218	138379218	C	T	SNP	PPP1R26	ENST00000356818	human	ensembl	74_37	+1	known	silent	c.2862	p.S954	0.000	NULL	NULL	-	no_errors	PPP1R26	HGNC	ENSG00000196422	tier1	-	-	47	0	0.00	36	4	10.00
PRAMEF17	0	genome.wustl.edu	37	1	13716931	13716931	+	Silent	SNP	A	A	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	13716931	13716931	A	C	SNP	PRAMEF17	ENST00000376098	human	ensembl	74_37	+1	known	silent	c.418	p.R140	0.000	NULL	NULL	-	no_errors	PRAMEF17	HGNC	ENSG00000204479	tier1	-	-	334	0	0.00	170	66	27.97
PREX1	0	genome.wustl.edu	37	20	47351176	47351176	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	47351176	47351176	G	C	SNP	PREX1	ENST00000371941	human	ensembl	74_37	-1	known	missense	c.426	p.F142L	1.000	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,pfscan_DH-domain	pfam_DH-domain,pfam_DEP_dom,pfam_Pleckstrin_homology,superfamily_DH-domain,superfamily_PDZ,smart_DH-domain,smart_Pleckstrin_homology,smart_DEP_dom,smart_PDZ,pfscan_DEP_dom,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PREX1	HGNC	ENSG00000124126	tier1	-	-	24	0	0.00	23	17	42.50
PRKXP1	0	genome.wustl.edu	37	15	101088125	101088126	+	RNA	INS	-	-	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	101088125	101088126	-	T	INS	PRKXP1	ENST00000602585	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	RP11-526I2.5	Clone_based_vega_gene	ENSG00000270127	tier1			25	0	0.00	27	5	15.62
PRPH2	0	genome.wustl.edu	37	6	42689525	42689525	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	6	42689525	42689525	C	T	SNP	PRPH2	ENST00000230381	human	ensembl	74_37	-1	known	missense	c.548	p.R183H	1.000	pfam_Tetraspanin/Peripherin,superfamily_Tetraspanin_EC2,prints_Peripherin/rom-1	pfam_Tetraspanin/Peripherin,superfamily_Tetraspanin_EC2,prints_Peripherin/rom-1	-	no_errors	PRPH2	HGNC	ENSG00000112619	tier1	-	-	64	0	0.00	21	39	62.90
PRRC2C	0	genome.wustl.edu	37	1	171558576	171558576	+	Silent	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	171558576	171558576	T	C	SNP	PRRC2C	ENST00000392078	human	ensembl	74_37	+1	known	silent	c.8268	p.P2756	1.000	NULL	pfam_BAT2_N	-	no_errors	PRRC2C	HGNC	ENSG00000117523	tier1	-	-	43	0	0.00	44	4	8.33
PRTG	0	genome.wustl.edu	37	15	55971641	55971641	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	55971641	55971641	G	C	SNP	PRTG	ENST00000389286	human	ensembl	74_37	-1	known	missense	c.976	p.P326A	1.000	NULL	pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	PRTG	HGNC	ENSG00000166450	tier1	-	-	31	0	0.00	14	17	54.84
PSMG1	0	genome.wustl.edu	37	21	40555233	40555235	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	CCT	CCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	21	40555233	40555235	CCT	-	DEL	PSMG1	ENST00000331573	human	ensembl	74_37	-1	known	in_frame_del	c.79_77	p.E26in_frame_del	0.012:0.015:0.023	pirsf_Proteasome_assmbl_chp_1	pirsf_Proteasome_assmbl_chp_1	-	no_errors	PSMG1	HGNC	ENSG00000183527	tier1			18	0	0.00	7	2	22.22
PTPLAD1	0	genome.wustl.edu	37	15	65864687	65864687	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	65864687	65864687	T	C	SNP	PTPLAD1	ENST00000261875	human	ensembl	74_37	+1	known	missense	c.995	p.L332P	1.000	pfam_Tyr_Pase-like_PTPLA	pfam_Tyr_Pase-like_PTPLA,pfam_CS_dom,superfamily_HSP20-like_chaperone,pfscan_CS_dom	-	no_errors	PTPLAD1	HGNC	ENSG00000074696	tier1	-	-	62	0	0.00	48	25	34.25
PTPN13	0	genome.wustl.edu	37	4	87718046	87718046	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	87718046	87718046	G	A	SNP	PTPN13	ENST00000436978	human	ensembl	74_37	+1	known	missense	c.6380	p.C2127Y	0.999	pirsf_Tyr_Pase_non-rcpt_typ-13	pirsf_Tyr_Pase_non-rcpt_typ-13,pfam_Tyr_Pase_rcpt/non-rcpt,pfam_PDZ,pfam_FERM_central,pfam_FERM_PH-like_C,pfam_FERM_N,superfamily_FERM_central,superfamily_PDZ,superfamily_PAZ_dom,smart_KIND,smart_Band_41_domain,smart_PDZ,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,prints_Tyr_Pase_rcpt/non-rcpt,prints_Band_41_fam,pfscan_FERM_domain,pfscan_PDZ,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPN13	HGNC	ENSG00000163629	tier1	-	-	130	0	0.00	20	49	70.00
PTPRN2	0	genome.wustl.edu	37	7	157475486	157475486	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	157475486	157475486	C	T	SNP	PTPRN2	ENST00000404321	human	ensembl	74_37	-1	known	silent	c.2001	p.Q667	0.961	NULL	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Receptor_IA-2,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRN2	HGNC	ENSG00000155093	tier1	-	-	49	0	0.00	43	4	8.33
RAB4A	0	genome.wustl.edu	37	1	229433269	229433269	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	229433269	229433269	G	T	SNP	RAB4A	ENST00000366690	human	ensembl	74_37	+1	known	missense	c.331	p.A111S	1.000	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,pfam_Gtr1_RagA,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RAB4A	HGNC	ENSG00000168118				39	0	0.00	54	4	6.90
RALBP1	0	genome.wustl.edu	37	18	9517255	9517255	+	Nonsense_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	18	9517255	9517255	C	A	SNP	RALBP1	ENST00000019317	human	ensembl	74_37	+1	known	nonsense	c.657	p.Y219*	0.997	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	RALBP1	HGNC	ENSG00000017797				68	0	0.00	32	2	5.88
RASSF2	0	genome.wustl.edu	37	20	4776546	4776546	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	4776546	4776546	G	A	SNP	RASSF2	ENST00000379376	human	ensembl	74_37	-1	known	silent	c.202	p.L68	0.986	NULL	pfam_Ras-assoc,smart_Ras-assoc,pfscan_Ras-assoc,pfscan_SARAH_dom	-	no_errors	RASSF2	HGNC	ENSG00000101265	tier1	-	-	41	0	0.00	35	13	27.08
RBM4	0	genome.wustl.edu	37	11	66413571	66413571	+	RNA	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	66413571	66413571	C	T	SNP	RBM4	ENST00000515838	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	RBM4	HGNC	ENSG00000173933	tier1	-	-	86	0	0.00	64	53	45.30
RIMKLA	0	genome.wustl.edu	37	1	42875740	42875740	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	42875740	42875740	G	T	SNP	RIMKLA	ENST00000431473	human	ensembl	74_37	+1	known	missense	c.567	p.Q189H	1.000	pfam_ATP-grasp_RimK-type,pfam_GSHS_ATP-bd,pfam_ATP-grasp_DUF201-type,pfscan_ATP-grasp,tigrfam_RpS6_RimK/Lys_biosynth_LsyX	pfam_ATP-grasp_RimK-type,pfam_GSHS_ATP-bd,pfam_ATP-grasp_DUF201-type,pfscan_ATP-grasp,tigrfam_RpS6_RimK/Lys_biosynth_LsyX	-	no_errors	RIMKLA	HGNC	ENSG00000177181	tier1	-	-	65	0	0.00	58	6	9.38
RNF213	0	genome.wustl.edu	37	17	78363879	78363879	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	78363879	78363879	G	T	SNP	RNF213	ENST00000582970	human	ensembl	74_37	+1	known	missense	c.15353	p.S5118I	0.008	NULL	superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF213	HGNC	ENSG00000173821				45	0	0.00	51	3	5.56
RP1	0	genome.wustl.edu	37	8	55540273	55540273	+	Missense_Mutation	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	55540273	55540273	T	G	SNP	RP1	ENST00000220676	human	ensembl	74_37	+1	known	missense	c.3831	p.S1277R	0.000	NULL	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	-	no_errors	RP1	HGNC	ENSG00000104237	tier1	-	-	102	0	0.00	61	35	36.46
RTN4	0	genome.wustl.edu	37	2	55199859	55199859	+	RNA	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	55199859	55199859	A	G	SNP	RTN4	ENST00000486085	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RTN4	HGNC	ENSG00000115310	tier1	-	-	16	0	0.00	1	18	94.74
RYR1	0	genome.wustl.edu	37	19	38946168	38946168	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	38946168	38946168	C	T	SNP	RYR1	ENST00000359596	human	ensembl	74_37	+1	known	missense	c.1654	p.R552W	1.000	pfam_Ca-rel_channel	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,superfamily_MG_RAP_rcpt_1,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_MIR_motif	-	no_errors	RYR1	HGNC	ENSG00000196218	tier1	rs193922770	-	70	0	0.00	59	12	16.90
SALL1	0	genome.wustl.edu	37	16	51174681	51174681	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	51174681	51174681	G	T	SNP	SALL1	ENST00000251020	human	ensembl	74_37	-1	known	missense	c.1452	p.N484K	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SALL1	HGNC	ENSG00000103449	tier1	-	-	30	0	0.00	5	22	81.48
SCAP	0	genome.wustl.edu	37	3	47467561	47467561	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	47467561	47467561	T	A	SNP	SCAP	ENST00000265565	human	ensembl	74_37	-1	known	missense	c.836	p.E279V	1.000	NULL	pfam_Patched,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_SSD,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	SCAP	HGNC	ENSG00000114650	tier1	-	-	50	0	0.00	10	22	68.75
SCN2A	0	genome.wustl.edu	37	2	166245328	166245328	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	166245328	166245328	T	C	SNP	SCN2A	ENST00000283256	human	ensembl	74_37	+1	known	missense	c.5012	p.M1671T	1.000	pfam_Ion_trans_dom,pfam_PKD1_2_channel	pfam_Ion_trans_dom,pfam_Na_trans_assoc,pfam_DUF3451,pfam_PKD1_2_channel,smart_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2,pfscan_IQ_motif_EF-hand-BS	-	no_errors	SCN2A	HGNC	ENSG00000136531	tier1	-	-	144	0	0.00	90	50	35.71
SCN3B	0	genome.wustl.edu	37	11	123513207	123513207	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	123513207	123513207	T	A	SNP	SCN3B	ENST00000299333	human	ensembl	74_37	-1	known	missense	c.392	p.H131L	1.000	pfam_Ig_V-set,smart_Ig_sub	pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	SCN3B	HGNC	ENSG00000166257	tier1	-	-	54	0	0.00	38	26	40.62
SEL1L3	0	genome.wustl.edu	37	4	25783966	25783968	+	In_Frame_Del	DEL	CTT	CTT	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	CTT	CTT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	25783966	25783968	CTT	-	DEL	SEL1L3	ENST00000399878	human	ensembl	74_37	-1	known	in_frame_del	c.2355_2353	p.K785in_frame_del	0.999:0.999:0.964	pfam_Sel1-like,smart_Sel1-like	pfam_Sel1-like,superfamily_ConA-like_lec_gl_sf,smart_Sel1-like	-	no_errors	SEL1L3	HGNC	ENSG00000091490	tier1			78	0	0.00	12	22	64.71
SEMA5B	0	genome.wustl.edu	37	3	122632261	122632261	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	122632261	122632261	G	A	SNP	SEMA5B	ENST00000451055	human	ensembl	74_37	-1	known	missense	c.2453	p.T818M	0.999	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Semap_dom,pfam_Thrombospondin_1_rpt,superfamily_Semap_dom,superfamily_Thrombospondin_1_rpt,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_Thrombospondin_1_rpt,pfscan_Semap_dom,pfscan_Thrombospondin_1_rpt	-	no_errors	SEMA5B	HGNC	ENSG00000082684	tier1	-	-	19	0	0.00	5	3	37.50
SF3B2	0	genome.wustl.edu	37	11	65824803	65824803	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	65824803	65824803	G	A	SNP	SF3B2	ENST00000322535	human	ensembl	74_37	+1	known	missense	c.734	p.R245Q	0.645	NULL	pfam_DUF382,pfam_PSP,pfam_SAP_dom,smart_SAP_dom,smart_PSP,pfscan_SAP_dom	-	no_errors	SF3B2	HGNC	ENSG00000087365	tier1	-	-	55	0	0.00	25	17	39.53
SFMBT2	0	genome.wustl.edu	37	10	7218087	7218087	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	7218087	7218087	G	A	SNP	SFMBT2	ENST00000361972	human	ensembl	74_37	-1	known	missense	c.1849	p.R617W	0.998	pfam_DUF3588	pfam_Mbt,pfam_DUF3588,pfam_SAM_type1,pfam_Pointed_dom,superfamily_SAM/pointed,superfamily_ARM-type_fold,smart_Mbt,smart_SAM,pfscan_Mbt	-	no_errors	SFMBT2	HGNC	ENSG00000198879				62	0	0.00	51	3	5.56
SIRPG	0	genome.wustl.edu	37	20	1615969	1615969	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	1615969	1615969	C	T	SNP	SIRPG	ENST00000303415	human	ensembl	74_37	-1	known	missense	c.1025	p.R342H	0.000	smart_Ig_sub	pfam_Ig_C1-set,pfam_CD80_C2-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	SIRPG	HGNC	ENSG00000089012	tier1	-	-	106	0	0.00	63	42	40.00
SKIV2L2	0	genome.wustl.edu	37	5	54710013	54710013	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	54710013	54710013	A	G	SNP	SKIV2L2	ENST00000230640	human	ensembl	74_37	+1	known	missense	c.2755	p.S919G	1.000	pfam_DSH_C,pirsf_RNA_helicase_ATP-dep_SK12/DOB1	pfam_DSH_C,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pirsf_RNA_helicase_ATP-dep_SK12/DOB1,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	SKIV2L2	HGNC	ENSG00000039123	tier1	-	-	87	0	0.00	48	4	7.69
SLC14A2	0	genome.wustl.edu	37	18	43248375	43248375	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	18	43248375	43248375	G	A	SNP	SLC14A2	ENST00000255226	human	ensembl	74_37	+1	known	missense	c.1969	p.V657M	1.000	pfam_Urea_transporter	pfam_Urea_transporter	-	no_errors	SLC14A2	HGNC	ENSG00000132874	tier1	-	-	82	0	0.00	45	5	10.00
SLC17A6	0	genome.wustl.edu	37	11	22384351	22384351	+	Missense_Mutation	SNP	C	C	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	22384351	22384351	C	A	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.728	p.S243Y	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664	tier1	-	-	102	0	0.00	48	23	32.39
SLC17A6	0	genome.wustl.edu	37	11	22384363	22384363	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	22384363	22384363	A	G	SNP	SLC17A6	ENST00000263160	human	ensembl	74_37	+1	known	missense	c.740	p.Y247C	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A6	HGNC	ENSG00000091664	tier1	-	-	103	0	0.00	44	21	31.82
SLC26A9	0	genome.wustl.edu	37	1	205890954	205890954	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	205890954	205890954	G	C	SNP	SLC26A9	ENST00000340781	human	ensembl	74_37	-1	known	missense	c.1795	p.Q599E	1.000	pfam_STAS_dom,superfamily_STAS_dom,pfscan_STAS_dom,tigrfam_SulP_transpt	pfam_Sulph_transpt,pfam_STAS_dom,superfamily_STAS_dom,pfscan_STAS_dom,tigrfam_SulP_transpt	-	no_errors	SLC26A9	HGNC	ENSG00000174502	tier1	-	-	44	0	0.00	45	8	15.09
SLC28A3	0	genome.wustl.edu	37	9	86905095	86905095	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	9	86905095	86905095	C	T	SNP	SLC28A3	ENST00000376238	human	ensembl	74_37	-1	known	missense	c.1123	p.V375M	0.998	pfam_Nucleoside_recog_Gate,tigrfam_C_nuclsd_transpt_met_bac	pfam_Nucleos_tra2_C,pfam_Nuclsd_transpt2,pfam_Nucleoside_recog_Gate,tigrfam_C_nuclsd_transpt_met_bac	-	no_errors	SLC28A3	HGNC	ENSG00000197506	tier1	-	-	81	0	0.00	40	29	42.03
SLC35F5	0	genome.wustl.edu	37	2	114475412	114475412	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	114475412	114475412	G	C	SNP	SLC35F5	ENST00000245680	human	ensembl	74_37	-1	known	missense	c.1512	p.S504R	0.998	NULL	pfam_DMT	-	no_errors	SLC35F5	HGNC	ENSG00000115084	tier1	-	-	30	0	0.00	19	14	42.42
SMAD4	0	genome.wustl.edu	37	18	48591919	48591919	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	18	48591919	48591919	G	A	SNP	SMAD4	ENST00000342988	human	ensembl	74_37	+1	known	missense	c.1082	p.R361H	1.000	pfam_SMAD_dom_Dwarfin-type,superfamily_SMAD_FHA_domain,smart_SMAD_dom_Dwarfin-type,pfscan_SMAD_dom_Dwarfin-type	pfam_SMAD_dom_Dwarfin-type,pfam_MAD_homology1_Dwarfin-type,superfamily_SMAD_FHA_domain,superfamily_MAD_homology_MH1,smart_MAD_homology1_Dwarfin-type,smart_SMAD_dom_Dwarfin-type,pfscan_MAD_homology_MH1,pfscan_SMAD_dom_Dwarfin-type	-	no_errors	SMAD4	HGNC	ENSG00000141646	tier1	-	-	87	0	0.00	11	36	76.60
SMO	0	genome.wustl.edu	37	7	128845505	128845505	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	128845505	128845505	T	C	SNP	SMO	ENST00000249373	human	ensembl	74_37	+1	known	missense	c.802	p.F268L	1.000	pfam_Frizzled,pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_Frizzled	pfam_Frizzled,pfam_Frizzled_dom,pfam_GPCR_2_secretin-like,superfamily_Frizzled_dom,smart_Frizzled_dom,pfscan_Frizzled_dom,pfscan_GPCR_2-like,prints_Frizzled	-	no_errors	SMO	HGNC	ENSG00000128602	tier1	-	-	40	0	0.00	8	33	80.49
SOX17	0	genome.wustl.edu	37	8	55372131	55372131	+	Missense_Mutation	SNP	T	T	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	55372131	55372131	T	G	SNP	SOX17	ENST00000297316	human	ensembl	74_37	+1	known	missense	c.821	p.L274R	0.023	pfam_Sox_C_TAD	pfam_Sox_C_TAD,pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	SOX17	HGNC	ENSG00000164736	tier1	-	-	18	0	0.00	8	10	55.56
SPEN	0	genome.wustl.edu	37	1	16255142	16255143	+	Frame_Shift_Del	DEL	GA	GA	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	GA	GA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	16255142	16255143	GA	-	DEL	SPEN	ENST00000375759	human	ensembl	74_37	+1	known	frame_shift_del	c.2407_2408	p.R806fs	0.999:1.000	NULL	pfam_RRM_dom,pfam_SPOC_C,superfamily_SPOC_like_C_dom,smart_RRM_dom,pfscan_SPOC_met,pfscan_RRM_dom	-	no_errors	SPEN	HGNC	ENSG00000065526	tier1			52	0	0.00	36	4	10.00
SPOCK3	0	genome.wustl.edu	37	4	167833799	167833799	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	4	167833799	167833799	C	T	SNP	SPOCK3	ENST00000357154	human	ensembl	74_37	-1	known	missense	c.455	p.G152D	1.000	pfam_Kazal_dom,smart_Kazal_dom	pfam_SPARC/Testican_Ca-bd-dom,pfam_Thyroglobulin_1,pfam_Kazal_dom,superfamily_Thyroglobulin_1,smart_Kazal_dom,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	-	no_errors	SPOCK3	HGNC	ENSG00000196104				87	0	0.00	40	3	6.98
SPSB2	0	genome.wustl.edu	37	12	6981290	6981290	+	Missense_Mutation	SNP	T	T	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	6981290	6981290	T	A	SNP	SPSB2	ENST00000519357	human	ensembl	74_37	-1	putative	missense	c.776	p.Q259L	0.000	NULL	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY	-	no_errors	SPSB2	HGNC	ENSG00000111671	tier1	-	-	49	0	0.00	19	21	52.50
SRCIN1	0	genome.wustl.edu	37	17	36708244	36708244	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	36708244	36708244	G	T	SNP	SRCIN1	ENST00000264659	human	ensembl	74_37	-1	known	missense	c.2605	p.L869M	0.181	NULL	pfam_AIP3_C	-	no_errors	SRCIN1	HGNC	ENSG00000017373				70	0	0.00	71	4	5.33
SSPO	0	genome.wustl.edu	37	7	149518163	149518163	+	RNA	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	7	149518163	149518163	G	T	SNP	SSPO	ENST00000378016	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.998	-	-	-	no_errors	SSPO	HGNC	ENSG00000197558	tier1	-	-	9	0	0.00	3	4	57.14
SUN5	0	genome.wustl.edu	37	20	31575539	31575539	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	31575539	31575539	T	C	SNP	SUN5	ENST00000356173	human	ensembl	74_37	-1	known	missense	c.656	p.H219R	0.625	superfamily_Galactose-bd-like	pfam_Sad1_UNC_C,superfamily_Galactose-bd-like	-	no_errors	SUN5	HGNC	ENSG00000167098	tier1	-	-	38	0	0.00	31	17	35.42
SYCP2	0	genome.wustl.edu	37	20	58494490	58494490	+	RNA	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	20	58494490	58494490	T	C	SNP	SYCP2	ENST00000476314	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.003	-	-	-	no_errors	SYCP2	HGNC	ENSG00000196074	tier1	-	-	34	0	0.00	25	25	50.00
TAPBPL	0	genome.wustl.edu	37	12	6575561	6575561	+	RNA	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	6575561	6575561	G	T	SNP	TAPBPL	ENST00000545700	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.032	-	-	-	no_errors	TAPBPL	HGNC	ENSG00000139192	tier1	-	-	28	0	0.00	17	6	26.09
TAS2R20	0	genome.wustl.edu	37	12	11150474	11150474	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	11150474	11150474	T	C	SNP	TAS2R20	ENST00000538986	human	ensembl	74_37	-1	known	missense	c.1	p.M1V	0.014	pfam_TAS2_rcpt	pfam_TAS2_rcpt	-	no_errors	TAS2R20	HGNC	ENSG00000255837	tier1	-	-	8	0	0.00	5	4	44.44
TBC1D8B	0	genome.wustl.edu	37	X	106066577	106066577	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	X	106066577	106066577	C	G	SNP	TBC1D8B	ENST00000357242	human	ensembl	74_37	+1	known	missense	c.708	p.H236Q	1.000	NULL	pfam_Rab-GTPase-TBC_dom,pfam_GRAM,superfamily_Rab-GTPase-TBC_dom,smart_GRAM,smart_Rab-GTPase-TBC_dom,pfscan_EF_hand_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D8B	HGNC	ENSG00000133138	tier1	-	-	55	0	0.00	54	4	6.90
TCEA1	0	genome.wustl.edu	37	8	54906287	54906287	+	Silent	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	54906287	54906287	G	A	SNP	TCEA1	ENST00000521604	human	ensembl	74_37	-1	known	silent	c.261	p.D87	1.000	superfamily_TFIIS_N,pirsf_TF_IIS-rel,tigrfam_TFSII	pfam_TFIIS_cen_dom,pfam_Znf_TFIIS,pfam_TFIIS_N,superfamily_TFIIS_cen_dom,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_TFS2M,smart_Znf_TFIIS,pirsf_TF_IIS-rel,pfscan_Znf_TFIIS,tigrfam_TFSII	-	no_errors	TCEA1	HGNC	ENSG00000187735	tier1	-	-	45	0	0.00	41	24	36.92
TIGD7	0	genome.wustl.edu	37	16	3350367	3350367	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	3350367	3350367	G	A	SNP	TIGD7	ENST00000268674	human	ensembl	74_37	-1	known	missense	c.248	p.A83V	1.000	pfam_HTH_CenpB_DNA-bd_dom,superfamily_Homeodomain-like,smart_HTH_CenpB_DNA-bd_dom	pfam_DDE_SF_endonuclease_CENPB-like,pfam_HTH_CenpB_DNA-bd_dom,pfam_HTH_Psq,superfamily_Homeodomain-like,smart_HTH_CenpB_DNA-bd_dom,pfscan_HTH_Psq	-	no_errors	TIGD7	HGNC	ENSG00000140993				51	0	0.00	36	2	5.26
TNFRSF18	0	genome.wustl.edu	37	1	1139264	1139264	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	1139264	1139264	G	A	SNP	TNFRSF18	ENST00000328596	human	ensembl	74_37	-1	known	missense	c.475	p.R159W	0.000	NULL	prints_TNFR_18	-	no_errors	TNFRSF18	HGNC	ENSG00000186891	tier1	-	-	22	0	0.00	31	6	16.22
TNR	0	genome.wustl.edu	37	1	175372725	175372725	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	175372725	175372725	C	T	SNP	TNR	ENST00000263525	human	ensembl	74_37	-1	known	missense	c.527	p.S176N	1.000	NULL	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNR	HGNC	ENSG00000116147	tier1	-	-	52	0	0.00	64	4	5.88
TOPBP1	0	genome.wustl.edu	37	3	133339082	133339082	+	Silent	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	3	133339082	133339082	T	C	SNP	TOPBP1	ENST00000260810	human	ensembl	74_37	-1	known	silent	c.3288	p.R1096	0.991	NULL	pfam_BRCT_dom,superfamily_BRCT_dom,superfamily_Secretoglobin,smart_BRCT_dom,pfscan_BRCT_dom	-	no_errors	TOPBP1	HGNC	ENSG00000163781	tier1	-	-	83	0	0.00	58	4	6.45
TP53	0	genome.wustl.edu	37	17	7578222	7578223	+	Frame_Shift_Del	DEL	TC	TC	-			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	TC	TC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	17	7578222	7578223	TC	-	DEL	TP53	ENST00000269305	human	ensembl	74_37	-1	known	frame_shift_del	c.627_626	p.R209fs	0.000:0.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1			55	0	0.00	15	30	66.67
TP53BP1	0	genome.wustl.edu	37	15	43699688	43699688	+	Nonsense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	43699688	43699688	G	A	SNP	TP53BP1	ENST00000382044	human	ensembl	74_37	-1	known	nonsense	c.5827	p.Q1943*	1.000	superfamily_BRCT_dom,smart_BRCT_dom,pfscan_BRCT_dom	pfam_53-BP1_Tudor,superfamily_BRCT_dom,smart_BRCT_dom,pfscan_BRCT_dom	-	no_errors	TP53BP1	HGNC	ENSG00000067369				26	0	0.00	30	2	6.25
TPTE2P6	0	genome.wustl.edu	37	13	25160825	25160825	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	13	25160825	25160825	G	A	SNP	TPTE2P6	ENST00000440905	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	TPTE2P6	HGNC	ENSG00000205822				38	0	0.00	23	3	11.54
TPTEP1	0	genome.wustl.edu	37	22	17083058	17083058	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	22	17083058	17083058	G	A	SNP	TPTEP1	ENST00000400593	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	TPTEP1	HGNC	ENSG00000100181	tier1	-	-	68	0	0.00	23	10	30.30
TRAM1	0	genome.wustl.edu	37	8	71520334	71520335	+	Frame_Shift_Ins	INS	-	-	AGAC			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	8	71520334	71520335	-	AGAC	INS	TRAM1	ENST00000262213	human	ensembl	74_37	-1	known	frame_shift_ins	c.101_100	p.F34fs	1.000:1.000	pirsf_Translocation_assoc_membrane	pfam_TRAM1,pfam_TLC-dom,smart_TLC-dom,pirsf_Translocation_assoc_membrane,pfscan_TLC-dom	-	no_errors	TRAM1	HGNC	ENSG00000067167	tier1			128	0	0.00	86	35	28.93
TRPM1	0	genome.wustl.edu	37	15	31330034	31330034	+	Silent	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	15	31330034	31330034	T	C	SNP	TRPM1	ENST00000542188	human	ensembl	74_37	-1	known	silent	c.2502	p.A834	0.994	NULL	pfam_Ion_trans_dom	-	no_errors	TRPM1	HGNC	ENSG00000134160	tier1	-	-	73	0	0.00	63	4	5.97
TRPM2	0	genome.wustl.edu	37	21	45799027	45799027	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	21	45799027	45799027	C	G	SNP	TRPM2	ENST00000300482	human	ensembl	74_37	+1	known	missense	c.1162	p.Q388E	1.000	NULL	pfam_Ion_trans_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	TRPM2	HGNC	ENSG00000142185				52	0	0.00	35	2	5.41
TRPM5	0	genome.wustl.edu	37	11	2436661	2436661	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	11	2436661	2436661	C	G	SNP	TRPM5	ENST00000452833	human	ensembl	74_37	-1	known	missense	c.1175	p.S392T	1.000	superfamily_Ankyrin_rpt-contain_dom	superfamily_Ankyrin_rpt-contain_dom	-	no_errors	TRPM5	HGNC	ENSG00000070985	tier1	-	-	54	0	0.00	31	11	26.19
TTC37	0	genome.wustl.edu	37	5	94833131	94833131	+	Silent	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	5	94833131	94833131	G	T	SNP	TTC37	ENST00000358746	human	ensembl	74_37	-1	known	silent	c.3625	p.R1209	0.120	NULL	pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TTC37	HGNC	ENSG00000198677	tier1	-	-	76	0	0.00	23	3	11.54
TTLL5	0	genome.wustl.edu	37	14	76175543	76175543	+	Silent	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	14	76175543	76175543	A	G	SNP	TTLL5	ENST00000286650	human	ensembl	74_37	+1	novel	silent	c.762	p.G254	0.011	NULL	pfam_TTL/TTLL_fam	-	no_errors	TTLL5	HGNC	ENSG00000119685	tier1	-	-	82	0	0.00	55	4	6.78
TTN	0	genome.wustl.edu	37	2	179598557	179598557	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	179598557	179598557	G	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.11827	p.L3943M	0.977	pfam_Ig_I-set,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	52	0	0.00	56	4	6.67
TXNIP	0	genome.wustl.edu	37	1	145442477	145442477	+	RNA	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	145442477	145442477	G	T	SNP	TXNIP	ENST00000475171	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.998	-	-	-	no_errors	TXNIP	HGNC	ENSG00000117289	tier1	-	-	78	0	0.00	58	4	6.45
UBR4	0	genome.wustl.edu	37	1	19499498	19499498	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	19499498	19499498	C	T	SNP	UBR4	ENST00000375267	human	ensembl	74_37	-1	known	silent	c.3381	p.A1127	0.740	NULL	superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_Znf_N-recognin_met,pfscan_Znf_N-recognin	-	no_errors	UBR4	HGNC	ENSG00000127481	tier1	-	-	53	0	0.00	68	12	15.00
UNC80	0	genome.wustl.edu	37	2	210683747	210683747	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	2	210683747	210683747	C	T	SNP	UNC80	ENST00000439458	human	ensembl	74_37	+1	known	missense	c.1724	p.A575V	1.000	NULL	NULL	-	no_errors	UNC80	HGNC	ENSG00000144406				40	0	0.00	38	2	5.00
USP14	0	genome.wustl.edu	37	18	203144	203144	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	18	203144	203144	G	T	SNP	USP14	ENST00000261601	human	ensembl	74_37	+1	known	missense	c.989	p.R330L	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Peptidase_C19/C67,smart_Ubiquitin_dom,pfscan_Peptidase_C19/C67,pfscan_Ubiquitin_supergroup	-	no_errors	USP14	HGNC	ENSG00000101557				66	0	0.00	23	2	8.00
VSIG10	0	genome.wustl.edu	37	12	118517313	118517313	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	118517313	118517313	C	T	SNP	VSIG10	ENST00000359236	human	ensembl	74_37	-1	known	missense	c.763	p.D255N	0.000	pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	VSIG10	HGNC	ENSG00000176834	tier1	-	-	46	0	0.00	23	13	36.11
VSIG10	0	genome.wustl.edu	37	12	118517327	118517327	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	12	118517327	118517327	C	T	SNP	VSIG10	ENST00000359236	human	ensembl	74_37	-1	known	missense	c.749	p.G250E	0.999	pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	VSIG10	HGNC	ENSG00000176834	tier1	-	-	51	0	0.00	26	17	39.53
VTI1A	0	genome.wustl.edu	37	10	114224339	114224339	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	114224339	114224339	C	T	SNP	VTI1A	ENST00000393077	human	ensembl	74_37	+1	known	missense	c.187	p.P63S	1.000	pfam_Vesicle_trsprt_v-SNARE_N,superfamily_t-SNARE	pfam_Vesicle_trsprt_v-SNARE_N,superfamily_t-SNARE,smart_T_SNARE_dom	-	no_errors	VTI1A	HGNC	ENSG00000151532				56	0	0.00	76	4	5.00
XPO6	0	genome.wustl.edu	37	16	28133018	28133018	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	16	28133018	28133018	G	T	SNP	XPO6	ENST00000304658	human	ensembl	74_37	-1	known	nonsense	c.1832	p.S611*	1.000	superfamily_ARM-type_fold	pfam_Exportin-1/Importin-b-like,pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N,pfscan_Importin-beta_N	-	no_errors	XPO6	HGNC	ENSG00000169180				60	0	0.00	36	2	5.26
ZDHHC16	0	genome.wustl.edu	37	10	99211446	99211446	+	Missense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	10	99211446	99211446	G	T	SNP	ZDHHC16	ENST00000370854	human	ensembl	74_37	+1	known	missense	c.14	p.R5L	1.000	NULL	pfam_Znf_DHHC_palmitoyltrfase,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC16	HGNC	ENSG00000171307				30	0	0.00	25	2	7.41
ZMYM6	0	genome.wustl.edu	37	1	35452920	35452920	+	Missense_Mutation	SNP	G	G	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	35452920	35452920	G	C	SNP	ZMYM6	ENST00000357182	human	ensembl	74_37	-1	known	missense	c.3763	p.Q1255E	1.000	superfamily_RNaseH-like_dom	pfam_Znf_MYM,superfamily_RNaseH-like_dom,smart_TRASH_dom	-	no_errors	ZMYM6	HGNC	ENSG00000163867	tier1	-	-	63	0	0.00	37	4	9.76
ZNF326	0	genome.wustl.edu	37	1	90486372	90486372	+	Missense_Mutation	SNP	T	T	C			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	90486372	90486372	T	C	SNP	ZNF326	ENST00000340281	human	ensembl	74_37	+1	known	missense	c.1196	p.M399T	1.000	pfam_AKAP95	pfam_AKAP95	-	no_errors	ZNF326	HGNC	ENSG00000162664	tier1	-	-	56	0	0.00	32	4	11.11
ZNF525	0	genome.wustl.edu	37	19	53885037	53885037	+	Missense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	53885037	53885037	G	A	SNP	ZNF525	ENST00000355326	human	ensembl	74_37	+1	known	missense	c.359	p.R120H	0.178	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF525	HGNC	ENSG00000203326				75	0	0.00	78	5	6.02
ZNF528	0	genome.wustl.edu	37	19	52919153	52919153	+	Nonsense_Mutation	SNP	G	G	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	52919153	52919153	G	T	SNP	ZNF528	ENST00000360465	human	ensembl	74_37	+1	known	nonsense	c.1048	p.E350*	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF528	HGNC	ENSG00000167555	tier1	-	-	42	0	0.00	33	9	21.43
ZNF544	0	genome.wustl.edu	37	19	58757716	58757716	+	Nonsense_Mutation	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	58757716	58757716	G	A	SNP	ZNF544	ENST00000269829	human	ensembl	74_37	+1	known	nonsense	c.83	p.W28*	0.960	pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF544	HGNC	ENSG00000198131	tier1	-	-	64	0	0.00	53	25	32.05
ZNF568	0	genome.wustl.edu	37	19	37440440	37440440	+	Nonsense_Mutation	SNP	A	A	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	37440440	37440440	A	T	SNP	ZNF568	ENST00000333987	human	ensembl	74_37	+1	known	nonsense	c.385	p.K129*	0.706	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF568	HGNC	ENSG00000198453	tier1	-	-	42	0	0.00	52	5	8.77
ZNF583	0	genome.wustl.edu	37	19	56935610	56935610	+	Missense_Mutation	SNP	C	C	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	56935610	56935610	C	G	SNP	ZNF583	ENST00000291598	human	ensembl	74_37	+1	known	missense	c.1583	p.S528C	0.009	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF583	HGNC	ENSG00000198440				58	0	0.00	42	3	6.67
ZNF644	0	genome.wustl.edu	37	1	91406698	91406698	+	Silent	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	91406698	91406698	C	T	SNP	ZNF644	ENST00000337393	human	ensembl	74_37	-1	known	silent	c.213	p.T71	0.473	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF644	HGNC	ENSG00000122482				55	0	0.00	32	2	5.88
ZNF695	0	genome.wustl.edu	37	1	247109044	247109044	+	RNA	SNP	G	G	A			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	1	247109044	247109044	G	A	SNP	ZNF695	ENST00000498046	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ZNF695	HGNC	ENSG00000197472	tier1	-	-	34	0	0.00	24	5	17.24
ZNF835	0	genome.wustl.edu	37	19	57174972	57174972	+	Missense_Mutation	SNP	C	C	T			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	57174972	57174972	C	T	SNP	ZNF835	ENST00000537055	human	ensembl	74_37	-1	known	missense	c.1595	p.R532H	0.000	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF835	HGNC	ENSG00000127903	tier1	-	-	30	0	0.00	23	23	50.00
ZNF844	0	genome.wustl.edu	37	19	12187160	12187160	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	12187160	12187160	A	G	SNP	ZNF844	ENST00000439326	human	ensembl	74_37	+1	known	missense	c.1225	p.I409V	0.000	NULL	pfam_Krueppel-associated_box,pfam_Znf_C2H2,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF844	HGNC	ENSG00000223547	tier1	-	-	81	0	0.00	34	17	33.33
ZNF844	0	genome.wustl.edu	37	19	12187502	12187502	+	Missense_Mutation	SNP	A	A	G			TCGA-2H-A9GN-01A-11D-A37C-09	TCGA-2H-A9GN-11A-11D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	a0ee65e5-b8ae-4ca2-9f7d-c1bf89dcd80d	fc594ce0-d420-4d5f-a048-884c5a935e71	19	12187502	12187502	A	G	SNP	ZNF844	ENST00000439326	human	ensembl	74_37	+1	known	missense	c.1567	p.K523E	0.004	NULL	pfam_Krueppel-associated_box,pfam_Znf_C2H2,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF844	HGNC	ENSG00000223547				80	0	0.00	32	2	5.88
