Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ABTB1	0	genome.wustl.edu	37	3	127396675	127396675	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	127396675	127396675	G	A	SNP	ABTB1	ENST00000232744	human	ensembl	74_37	+1	known	missense	c.1018	p.D340N	1.000	pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,pfscan_BTB/POZ-like	pfam_BTB_POZ,pfam_Ankyrin_rpt,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	-	no_errors	ABTB1	HGNC	ENSG00000114626				10	0	0.00	14	4	22.22
ABTB2	0	genome.wustl.edu	37	11	34378857	34378857	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	34378857	34378857	G	A	SNP	ABTB2	ENST00000435224	human	ensembl	74_37	-1	known	missense	c.274	p.P92S	1.000	NULL	pfam_BTB_POZ,pfam_Ankyrin_rpt,superfamily_Histone-fold,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	-	no_errors	ABTB2	HGNC	ENSG00000166016	tier1	-	-	38	0	0.00	37	10	21.28
ABTB2	0	genome.wustl.edu	37	11	34378866	34378866	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	34378866	34378866	G	A	SNP	ABTB2	ENST00000435224	human	ensembl	74_37	-1	known	missense	c.265	p.P89S	1.000	NULL	pfam_BTB_POZ,pfam_Ankyrin_rpt,superfamily_Histone-fold,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	-	no_errors	ABTB2	HGNC	ENSG00000166016	tier1	-	-	42	0	0.00	36	12	25.00
ABTB2	0	genome.wustl.edu	37	11	34378895	34378895	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	34378895	34378895	G	A	SNP	ABTB2	ENST00000435224	human	ensembl	74_37	-1	known	missense	c.236	p.P79L	1.000	NULL	pfam_BTB_POZ,pfam_Ankyrin_rpt,superfamily_Histone-fold,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	-	no_errors	ABTB2	HGNC	ENSG00000166016	tier1	-	-	47	0	0.00	33	13	28.26
ANKDD1A	0	genome.wustl.edu	37	15	65236929	65236929	+	Missense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	15	65236929	65236929	C	A	SNP	ANKDD1A	ENST00000380230	human	ensembl	74_37	+1	known	missense	c.1146	p.F382L	0.999	superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt	pfam_Ankyrin_rpt,pfam_Death_domain,superfamily_Ankyrin_rpt-contain_dom,superfamily_DEATH-like_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Death_domain,prints_Ankyrin_rpt	-	no_errors	ANKDD1A	HGNC	ENSG00000166839				19	0	0.00	22	4	15.38
ANKRD35	0	genome.wustl.edu	37	1	145563081	145563081	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	145563081	145563081	C	T	SNP	ANKRD35	ENST00000355594	human	ensembl	74_37	+1	known	silent	c.2769	p.C923	1.000	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD35	HGNC	ENSG00000198483				44	0	0.00	73	4	5.19
AP2A1	0	genome.wustl.edu	37	19	50303389	50303389	+	Silent	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	50303389	50303389	C	A	SNP	AP2A1	ENST00000354293	human	ensembl	74_37	+1	known	silent	c.1437	p.A479	0.015	pfam_Clathrin/coatomer_adapt-like_N,superfamily_ARM-type_fold,pirsf_AP2_complex_asu	pfam_Clathrin/coatomer_adapt-like_N,pfam_Clathrin_a-adaptin_app_sub_C,pfam_Clathrin_a/b/g-adaptin_app_Ig,superfamily_ARM-type_fold,superfamily_Coatomer/calthrin_app_sub_C,superfamily_Coatomer/clathrin_app_Ig-like,smart_Clathrin_a/b/g-adaptin_app_Ig,pirsf_AP2_complex_asu	-	no_errors	AP2A1	HGNC	ENSG00000196961				42	0	0.00	52	3	5.45
APITD1-CORT	0	genome.wustl.edu	37	1	10511557	10511557	+	Frame_Shift_Del	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	10511557	10511557	A	-	DEL	APITD1-CORT	ENST00000400900	human	ensembl	74_37	+1	known	frame_shift_del	c.400	p.R134fs	0.014	NULL	pfam_Somatostatin/Cortistatin_C,superfamily_Histone-fold	-	no_errors	APITD1-CORT	HGNC	ENSG00000251503	tier1			49	0	0.00	17	2	10.53
ARHGEF17	0	genome.wustl.edu	37	11	73068098	73068098	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	73068098	73068098	C	T	SNP	ARHGEF17	ENST00000263674	human	ensembl	74_37	+1	known	missense	c.3920	p.S1307F	1.000	NULL	pfam_DH-domain,superfamily_DH-domain,superfamily_WD40_repeat_dom,superfamily_Vinculin/catenin,smart_DH-domain,pfscan_DH-domain	-	no_errors	ARHGEF17	HGNC	ENSG00000110237	tier1	-	-	42	0	0.00	26	8	23.53
ATF6B	0	genome.wustl.edu	37	6	32083613	32083613	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	32083613	32083613	G	T	SNP	ATF6B	ENST00000375203	human	ensembl	74_37	-1	known	missense	c.2015	p.P672Q	0.968	NULL	pfam_bZIP,smart_bZIP,pfscan_bZIP	-	no_errors	ATF6B	HGNC	ENSG00000213676				39	0	0.00	34	4	10.53
ATP1A1	0	genome.wustl.edu	37	1	116932186	116932186	+	Missense_Mutation	SNP	A	A	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	116932186	116932186	A	T	SNP	ATP1A1	ENST00000295598	human	ensembl	74_37	+1	known	missense	c.880	p.I294F	0.185	pfam_ATPase_P-typ_transduc_dom_A,tigrfam_ATPase_P-typ_Na/K_IIC,tigrfam_Cation_transp_P_typ_ATPase	pfam_ATPase_P-typ_transduc_dom_A,pfam_ATPase_P-typ_cation-transptr_C,pfam_HAD-like_dom,pfam_ATPase_P-typ_cation-transptr_N,superfamily_ATPase_P-typ_cyto_domN,superfamily_HAD-like_dom,smart_ATPase_P-typ_cation-transptr_N,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Na/K_IIC,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP1A1	HGNC	ENSG00000163399	tier1	-	-	84	0	0.00	69	20	22.47
BAG6	0	genome.wustl.edu	37	6	31610093	31610093	+	Missense_Mutation	SNP	G	G	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	31610093	31610093	G	C	SNP	BAG6	ENST00000404765	human	ensembl	74_37	-1	known	missense	c.2131	p.P711A	1.000	NULL	pfam_DUF3538,pfam_Ubiquitin_dom,smart_Ubiquitin_dom,pfscan_Ubiquitin_supergroup	-	no_errors	BAG6	HGNC	ENSG00000204463				26	0	0.00	17	7	29.17
BBS1	0	genome.wustl.edu	37	11	66297394	66297394	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	66297394	66297394	G	A	SNP	BBS1	ENST00000419755	human	ensembl	74_37	+1	known	missense	c.1555	p.A519T	0.999	NULL	superfamily_Quinonprotein_ADH-like_supfam	-	no_errors	CTD-3074O7.11	Clone_based_vega_gene	ENSG00000256349				84	0	0.00	60	4	6.25
BUB1	0	genome.wustl.edu	37	2	111398882	111398882	+	Splice_Site	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	111398882	111398882	G	T	SNP	BUB1	ENST00000302759	human	ensembl	74_37	-1	known	splice_site	c.2783+2	e22+2	1.000	-	-	-	no_errors	BUB1	HGNC	ENSG00000169679	tier1	-	-	23	0	0.00	23	12	34.29
C17orf100	0	genome.wustl.edu	37	17	6555655	6555658	+	Frame_Shift_Del	DEL	GCCA	GCCA	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	GCCA	GCCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	6555655	6555658	GCCA	-	DEL	C17orf100	ENST00000391428	human	ensembl	74_37	+1	known	frame_shift_del	c.422_425	p.S145fs	0.122:0.120:0.117:0.113	NULL	NULL	-	no_errors	C17orf100	HGNC	ENSG00000212734	tier1			36	0	0.00	21	2	8.70
C2orf68	0	genome.wustl.edu	37	2	85838860	85838860	+	Missense_Mutation	SNP	T	T	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	85838860	85838860	T	A	SNP	C2orf68	ENST00000306336	human	ensembl	74_37	-1	known	missense	c.157	p.R53W	1.000	pfam_UPF0561	pfam_UPF0561	-	no_errors	C2orf68	HGNC	ENSG00000168887	tier1	-	-	36	0	0.00	19	11	36.67
CARD9	0	genome.wustl.edu	37	9	139262253	139262253	+	Missense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	139262253	139262253	C	A	SNP	CARD9	ENST00000371732	human	ensembl	74_37	-1	known	missense	c.1105	p.A369S	0.000	NULL	pfam_CARD,superfamily_DEATH-like_dom,pfscan_CARD	-	no_errors	CARD9	HGNC	ENSG00000187796	tier1	-	-	10	0	0.00	9	4	30.77
CASKIN2	0	genome.wustl.edu	37	17	73502696	73502696	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	73502696	73502696	C	T	SNP	CASKIN2	ENST00000321617	human	ensembl	74_37	-1	known	silent	c.585	p.L195	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_SAM_type1,pfam_SAM_2,pfam_SH3_2,superfamily_Ankyrin_rpt-contain_dom,superfamily_SAM/pointed,superfamily_SH3_domain,smart_Ankyrin_rpt,smart_SH3_domain,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_SAM,pfscan_SH3_domain,prints_Ankyrin_rpt	-	no_errors	CASKIN2	HGNC	ENSG00000177303				37	0	0.00	28	2	6.67
CD14	0	genome.wustl.edu	37	5	140012199	140012199	+	Nonsense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	140012199	140012199	C	A	SNP	CD14	ENST00000302014	human	ensembl	74_37	-1	known	nonsense	c.370	p.E124*	0.031	pirsf_Monocyte_diff_Ag_CD14	pfam_Leu-rich_rpt,pirsf_Monocyte_diff_Ag_CD14	-	no_errors	CD14	HGNC	ENSG00000170458				44	0	0.00	30	2	6.25
CD200R1	0	genome.wustl.edu	37	3	112643345	112643345	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	112643345	112643345	C	T	SNP	CD200R1	ENST00000308611	human	ensembl	74_37	-1	known	missense	c.916	p.V306I	0.005	NULL	pfam_CD80_C2-set,pfscan_Ig-like_dom	-	no_errors	CD200R1	HGNC	ENSG00000163606	tier1	-	-	51	0	0.00	76	23	23.23
CD5L	0	genome.wustl.edu	37	1	157805945	157805945	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	157805945	157805945	G	A	SNP	CD5L	ENST00000368174	human	ensembl	74_37	-1	known	missense	c.56	p.A19V	0.012	superfamily_Srcr_rcpt-rel	pfam_SRCR,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel,pfscan_SRCR,prints_SRCR	-	no_errors	CD5L	HGNC	ENSG00000073754	tier1	-	-	9	0	0.00	21	9	30.00
CDC40	0	genome.wustl.edu	37	6	110528714	110528714	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	110528714	110528714	G	A	SNP	CDC40	ENST00000307731	human	ensembl	74_37	+1	known	missense	c.412	p.A138T	1.000	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	CDC40	HGNC	ENSG00000168438	tier1	-	-	77	0	0.00	60	4	6.25
CDH10	0	genome.wustl.edu	37	5	24491785	24491785	+	Silent	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	24491785	24491785	T	C	SNP	CDH10	ENST00000264463	human	ensembl	74_37	-1	known	silent	c.1776	p.Q592	0.197	smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	CDH10	HGNC	ENSG00000040731	tier1	-	-	23	0	0.00	24	15	38.46
CDHR3	0	genome.wustl.edu	37	7	105668106	105668106	+	Splice_Site	SNP	A	A	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	105668106	105668106	A	T	SNP	CDHR3	ENST00000542731	human	ensembl	74_37	+1	known	splice_site	c.2259-2	e16-2	0.000	-	-	-	no_errors	CDHR3	HGNC	ENSG00000128536	tier1	rs145019687	-	42	0	0.00	33	5	11.90
CNPY3	0	genome.wustl.edu	37	6	42897358	42897360	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	TGC	TGC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	42897358	42897360	TGC	-	DEL	CNPY3	ENST00000372836	human	ensembl	74_37	+1	known	in_frame_del	c.50_52	p.L21in_frame_del	0.122:0.131:0.153	NULL	pfam_DUF3456	-	no_errors	CNPY3	HGNC	ENSG00000137161	tier1			20	0	0.00	19	3	13.64
CNTN6	0	genome.wustl.edu	37	3	1363504	1363504	+	Frame_Shift_Del	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	1363504	1363504	A	-	DEL	CNTN6	ENST00000350110	human	ensembl	74_37	+1	known	frame_shift_del	c.932	p.Q311fs	1.000	pfam_Ig_I-set,smart_Ig_sub	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Ig_V-set,pfam_Immunoglobulin,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	CNTN6	HGNC	ENSG00000134115	tier1			23	0	0.00	8	13	61.90
CRY2	0	genome.wustl.edu	37	11	45891258	45891258	+	Missense_Mutation	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	45891258	45891258	A	G	SNP	CRY2	ENST00000443527	human	ensembl	74_37	+1	known	missense	c.1147	p.I383V	1.000	pfam_Photolyase_FAD-bd/Cryptochr_C,superfamily_Photolyase_FAD-bd/Cryptochr_C	pfam_Photolyase_FAD-bd/Cryptochr_C,pfam_DNA_photolyase_N,superfamily_Photolyase_FAD-bd/Cryptochr_C,superfamily_DNA_photolyase_N	-	no_errors	CRY2	HGNC	ENSG00000121671	tier1	-	-	37	0	0.00	23	11	32.35
CTNND1	0	genome.wustl.edu	37	11	57563062	57563062	+	Frame_Shift_Del	DEL	T	T	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	57563062	57563062	T	-	DEL	CTNND1	ENST00000399050	human	ensembl	74_37	+1	known	frame_shift_del	c.281	p.L95fs	0.992	NULL	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	CTNND1	HGNC	ENSG00000198561	tier1			35	0	0.00	37	2	5.13
DCAF12	0	genome.wustl.edu	37	9	34089557	34089557	+	Silent	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	34089557	34089557	G	T	SNP	DCAF12	ENST00000361264	human	ensembl	74_37	-1	known	silent	c.1056	p.I352	1.000	superfamily_WD40_repeat_dom,smart_WD40_repeat	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	DCAF12	HGNC	ENSG00000198876	tier1	-	-	50	0	0.00	45	22	32.84
DDHD1	0	genome.wustl.edu	37	14	53525283	53525283	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	14	53525283	53525283	C	T	SNP	DDHD1	ENST00000323669	human	ensembl	74_37	-1	known	missense	c.1904	p.R635H	1.000	pfam_DDHD,pfscan_DDHD	pfam_DDHD,pfscan_DDHD	-	no_errors	DDHD1	HGNC	ENSG00000100523	tier1	-	-	53	0	0.00	60	4	6.25
DFNB31	0	genome.wustl.edu	37	9	117186643	117186643	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	117186643	117186643	G	T	SNP	DFNB31	ENST00000362057	human	ensembl	74_37	-1	known	missense	c.1387	p.L463M	0.996	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	DFNB31	HGNC	ENSG00000095397				49	0	0.00	37	2	5.13
DGCR8	0	genome.wustl.edu	37	22	20094812	20094812	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	22	20094812	20094812	G	T	SNP	DGCR8	ENST00000351989	human	ensembl	74_37	+1	known	missense	c.2015	p.G672V	1.000	pfam_dsRNA-bd_dom,smart_dsRNA-bd_dom	pfam_dsRNA-bd_dom,superfamily_WW_dom,smart_WW_dom,smart_dsRNA-bd_dom,pfscan_WW_dom,pfscan_dsRNA-bd_dom	-	no_errors	DGCR8	HGNC	ENSG00000128191				67	0	0.00	51	4	7.27
DMRTB1	0	genome.wustl.edu	37	1	53927253	53927253	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	53927253	53927253	C	T	SNP	DMRTB1	ENST00000371445	human	ensembl	74_37	+1	known	missense	c.685	p.P229S	0.000	NULL	pfam_DM_DNA-bd,superfamily_DM_DNA-bd,smart_DM_DNA-bd,pfscan_DM_DNA-bd	-	no_errors	DMRTB1	HGNC	ENSG00000143006	tier1	-	-	30	0	0.00	22	4	15.38
ENPEP	0	genome.wustl.edu	37	4	111430828	111430828	+	Frame_Shift_Del	DEL	T	T	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	111430828	111430828	T	-	DEL	ENPEP	ENST00000265162	human	ensembl	74_37	+1	known	frame_shift_del	c.1059	p.F354fs	1.000	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	ENPEP	HGNC	ENSG00000138792	tier1			43	0	0.00	37	2	5.13
ENSG00000237027	0	genome.wustl.edu	37	6	90276680	90276680	+	RNA	SNP	C	C	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	90276680	90276680	C	G	SNP	ENSG00000237027	ENST00000425588	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.994	-	-	-	no_errors	RP11-16C18.3	Clone_based_vega_gene	ENSG00000237027	tier1	-	-	22	0	0.00	7	10	58.82
ENSG00000244567	0	genome.wustl.edu	37	2	208687115	208687115	+	RNA	SNP	A	A	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	208687115	208687115	A	C	SNP	ENSG00000244567	ENST00000343987	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AC096772.6	Clone_based_vega_gene	ENSG00000244567	tier1	-	-	113	0	0.00	48	29	37.66
ENTPD2	0	genome.wustl.edu	37	9	139944734	139944734	+	Splice_Site	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	139944734	139944734	A	G	SNP	ENTPD2	ENST00000355097	human	ensembl	74_37	-1	known	splice_site	c.1029+2	e6+2	1.000	-	-	-	no_errors	ENTPD2	HGNC	ENSG00000054179				48	0	0.00	39	4	9.30
FAM199X	0	genome.wustl.edu	37	X	103432909	103432909	+	Missense_Mutation	SNP	C	C	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	X	103432909	103432909	C	G	SNP	FAM199X	ENST00000493442	human	ensembl	74_37	+1	known	missense	c.918	p.N306K	1.000	NULL	NULL	-	no_errors	FAM199X	HGNC	ENSG00000123575	tier1	-	-	9	0	0.00	5	12	70.59
FAM20A	0	genome.wustl.edu	37	17	66537011	66537011	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	66537011	66537011	C	T	SNP	FAM20A	ENST00000592554	human	ensembl	74_37	-1	known	missense	c.1198	p.A400T	1.000	pfam_DUF1193	pfam_DUF1193	-	no_errors	FAM20A	HGNC	ENSG00000108950				45	0	0.00	75	4	5.06
FGG	0	genome.wustl.edu	37	4	155528020	155528020	+	Silent	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	155528020	155528020	G	A	SNP	FGG	ENST00000336098	human	ensembl	74_37	-1	known	silent	c.966	p.G322	0.007	pfam_Fibrinogen_a/b/g_C_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	pfam_Fibrinogen_a/b/g_C_dom,pfam_Fibrinogen_a/b/g_coil_dom,superfamily_Fibrinogen_a/b/g_C_dom,smart_Fibrinogen_a/b/g_C_dom	-	no_errors	FGG	HGNC	ENSG00000171557	tier1	rs146218442	-	43	0	0.00	10	13	56.52
FOXS1	0	genome.wustl.edu	37	20	30432392	30432392	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	20	30432392	30432392	G	-	DEL	FOXS1	ENST00000375978	human	ensembl	74_37	-1	known	frame_shift_del	c.954	p.C319fs	0.998	NULL	pfam_TF_fork_head,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head	-	no_errors	FOXS1	HGNC	ENSG00000179772	tier1			86	0	0.00	38	2	5.00
GGN	0	genome.wustl.edu	37	19	38876616	38876616	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	38876616	38876616	G	T	SNP	GGN	ENST00000334928	human	ensembl	74_37	-1	known	missense	c.1286	p.P429Q	0.003	NULL	NULL	-	no_errors	GGN	HGNC	ENSG00000179168				16	0	0.00	9	2	18.18
GLB1L3	0	genome.wustl.edu	37	11	134188557	134188557	+	Silent	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	134188557	134188557	A	G	SNP	GLB1L3	ENST00000431683	human	ensembl	74_37	+1	known	silent	c.1812	p.G604	0.012	superfamily_Galactose-bd-like,prints_Glycoside_Hdrlase_35	pfam_Glycoside_Hdrlase_35,pfam_Glyco_hydro_42_N,superfamily_Glycoside_hydrolase_SF,superfamily_Galactose-bd-like,prints_Glycoside_Hdrlase_35	-	no_errors	GLB1L3	HGNC	ENSG00000166105	tier1	-	-	48	0	0.00	33	17	34.00
GOLGB1	0	genome.wustl.edu	37	3	121400679	121400679	+	Silent	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	121400679	121400679	A	G	SNP	GOLGB1	ENST00000340645	human	ensembl	74_37	-1	known	silent	c.8713	p.L2905	1.000	NULL	superfamily_Prefoldin,superfamily_STAT_TF_coiled-coil,smart_Leu_zip_homeo	-	no_errors	GOLGB1	HGNC	ENSG00000173230	tier1	-	-	50	0	0.00	33	22	40.00
GPR75-ASB3	0	genome.wustl.edu	37	2	53990717	53990717	+	RNA	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	53990717	53990717	C	A	SNP	GPR75-ASB3	ENST00000414369	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	GPR75-ASB3	HGNC	ENSG00000115239	tier1	-	-	62	0	0.00	34	4	10.53
GPRIN2	0	genome.wustl.edu	37	10	46999668	46999668	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	46999668	46999668	C	T	SNP	GPRIN2	ENST00000374314	human	ensembl	74_37	+1	known	missense	c.788	p.A263V	0.993	NULL	NULL	-	no_errors	GPRIN2	HGNC	ENSG00000204175	tier1	-	-	33	0	0.00	14	6	30.00
GRHL2	0	genome.wustl.edu	37	8	102555638	102555638	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	102555638	102555638	C	T	SNP	GRHL2	ENST00000251808	human	ensembl	74_37	+1	known	missense	c.190	p.L64F	1.000	NULL	pfam_CP2	-	no_errors	GRHL2	HGNC	ENSG00000083307	tier1	-	-	43	0	0.00	21	30	58.82
GTPBP10	0	genome.wustl.edu	37	7	89984453	89984453	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	89984453	89984453	G	A	SNP	GTPBP10	ENST00000222511	human	ensembl	74_37	+1	known	missense	c.373	p.G125S	1.000	pfam_GTP1_OBG_dom,superfamily_GTP1_OBG_dom,pirsf_GTP-bd_Obg/CgtA	pfam_GTP_binding_domain,pfam_GTP1_OBG_dom,pfam_Fe2_transport_prot_B_N,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,superfamily_GTP1_OBG_dom,pirsf_GTP-bd_Obg/CgtA,prints_GTP_binding_domain	-	no_errors	GTPBP10	HGNC	ENSG00000105793				76	0	0.00	54	3	5.26
HMGXB4	0	genome.wustl.edu	37	22	35661543	35661544	+	Frame_Shift_Ins	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	22	35661543	35661544	-	A	INS	HMGXB4	ENST00000216106	human	ensembl	74_37	+1	known	frame_shift_ins	c.1162_1163	p.K392fs	1.000:1.000	superfamily_HMG_box_dom	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	HMGXB4	HGNC	ENSG00000100281	tier1			11	0	0.00	13	3	18.75
HS3ST1	0	genome.wustl.edu	37	4	11400816	11400816	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	11400816	11400816	G	A	SNP	HS3ST1	ENST00000002596	human	ensembl	74_37	-1	known	missense	c.814	p.R272W	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	HS3ST1	HGNC	ENSG00000002587	tier1	-	-	47	0	0.00	29	5	14.71
HTR1E	0	genome.wustl.edu	37	6	87725923	87725923	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	87725923	87725923	C	T	SNP	HTR1E	ENST00000305344	human	ensembl	74_37	+1	known	missense	c.871	p.R291C	0.569	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_5HT_rcpt	-	no_errors	HTR1E	HGNC	ENSG00000168830	tier1	-	-	72	0	0.00	40	13	24.53
HYAL2	0	genome.wustl.edu	37	3	50357378	50357378	+	Silent	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	50357378	50357378	G	A	SNP	HYAL2	ENST00000357750	human	ensembl	74_37	-1	known	silent	c.543	p.F181	0.000	pfam_Hyaluronidase,superfamily_Glycoside_hydrolase_SF,pirsf_Hyaluronidase	pfam_Hyaluronidase,superfamily_Glycoside_hydrolase_SF,pirsf_Hyaluronidase,prints_Hyaluronidase	-	no_errors	HYAL2	HGNC	ENSG00000068001				27	0	0.00	21	2	8.70
IFNLR1	0	genome.wustl.edu	37	1	24488008	24488008	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	24488008	24488008	G	-	DEL	IFNLR1	ENST00000374418	human	ensembl	74_37	-1	known	frame_shift_del	c.534	p.R179fs	0.000	NULL	superfamily_Fibronectin_type3	-	no_errors	IFNLR1	HGNC	ENSG00000185436	tier1			49	0	0.00	24	3	11.11
IMMP2L	0	genome.wustl.edu	37	7	111161482	111161482	+	Missense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	111161482	111161482	C	A	SNP	IMMP2L	ENST00000331762	human	ensembl	74_37	-1	known	missense	c.22	p.V8L	0.988	NULL	pfam_Peptidase_S24_S26,superfamily_Peptidase_S24_S26A/B/C,prints_Pept_S26A_signal_pept_1,tigrfam_Pept_S26A_signal_pept_1	-	no_errors	IMMP2L	HGNC	ENSG00000184903	tier1	-	-	35	0	0.00	17	11	39.29
INTS7	0	genome.wustl.edu	37	1	212148519	212148519	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	212148519	212148519	C	T	SNP	INTS7	ENST00000440600	human	ensembl	74_37	-1	known	missense	c.1657	p.A553T	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	INTS7	HGNC	ENSG00000143493				20	0	0.00	34	4	10.53
ITGAL	0	genome.wustl.edu	37	16	30484186	30484186	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	16	30484186	30484186	G	A	SNP	ITGAL	ENST00000356798	human	ensembl	74_37	+1	known	missense	c.28	p.A10T	0.000	NULL	pfam_Integrin_alpha-2,pfam_VWF_A,pfam_FG-GAP,pfam_Integrin_alpha_C_CS,smart_Int_alpha_beta-p,smart_VWF_A,prints_Integrin_alpha,pfscan_VWF_A	-	no_errors	ITGAL	HGNC	ENSG00000005844	tier1	-	-	49	0	0.00	61	4	6.15
ITPA	0	genome.wustl.edu	37	20	3194687	3194687	+	Silent	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	20	3194687	3194687	G	A	SNP	ITPA	ENST00000380113	human	ensembl	74_37	+1	known	silent	c.246	p.G82	0.694	pfam_Ham1p-like,tigrfam_Ham1p-like	pfam_Ham1p-like,tigrfam_Ham1p-like	-	no_errors	ITPA	HGNC	ENSG00000125877	tier1	-	-	82	0	0.00	26	35	56.45
JAKMIP3	0	genome.wustl.edu	37	10	133978235	133978235	+	Frame_Shift_Del	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	133978235	133978235	A	-	DEL	JAKMIP3	ENST00000298622	human	ensembl	74_37	+1	known	frame_shift_del	c.2480	p.K828fs	1.000	NULL	NULL	-	no_errors	JAKMIP3	HGNC	ENSG00000188385	tier1			22	0	0.00	12	2	14.29
KBTBD7	0	genome.wustl.edu	37	13	41767331	41767331	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	13	41767331	41767331	G	A	SNP	KBTBD7	ENST00000379483	human	ensembl	74_37	-1	known	missense	c.1063	p.P355S	1.000	pirsf_Kelch-like_gigaxonin	pfam_BTB_POZ,pfam_BACK,pfam_Kelch_1,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like	-	no_errors	KBTBD7	HGNC	ENSG00000120696	tier1	-	-	54	0	0.00	40	6	13.04
KDM6A	0	genome.wustl.edu	37	X	44941834	44941834	+	Missense_Mutation	SNP	A	A	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	X	44941834	44941834	A	T	SNP	KDM6A	ENST00000382899	human	ensembl	74_37	+1	known	missense	c.3179	p.K1060I	1.000	NULL	pfam_JmjC_dom,pfam_TPR_1,smart_TPR_repeat,smart_JmjC_dom,pfscan_JmjC_dom,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	KDM6A	HGNC	ENSG00000147050	tier1	-	-	60	0	0.00	8	32	80.00
KIAA0196	0	genome.wustl.edu	37	8	126061249	126061249	+	Missense_Mutation	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	126061249	126061249	T	C	SNP	KIAA0196	ENST00000318410	human	ensembl	74_37	-1	known	missense	c.2378	p.K793R	1.000	pfam_WASH_strumpellin	pfam_WASH_strumpellin,superfamily_Ig_E-set	-	no_errors	KIAA0196	HGNC	ENSG00000164961	tier1	-	-	48	0	0.00	40	11	21.57
KITLG	0	genome.wustl.edu	37	12	88910245	88910245	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	12	88910245	88910245	C	T	SNP	KITLG	ENST00000228280	human	ensembl	74_37	-1	known	missense	c.386	p.S129N	0.011	pfam_SCF,superfamily_4_helix_cytokine-like_core,pirsf_SCF	pfam_SCF,superfamily_4_helix_cytokine-like_core,pirsf_SCF	-	no_errors	KITLG	HGNC	ENSG00000049130	tier1	-	-	80	0	0.00	43	22	33.85
KLHL3	0	genome.wustl.edu	37	5	136957467	136957468	+	RNA	DEL	AC	AC	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	AC	AC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	136957467	136957468	AC	-	DEL	KLHL3	ENST00000506873	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.424:0.441	-	-	-	no_errors	KLHL3	HGNC	ENSG00000146021	tier1			19	0	0.00	14	5	26.32
KLHL8	0	genome.wustl.edu	37	4	88097982	88097982	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	88097982	88097982	G	A	SNP	KLHL8	ENST00000273963	human	ensembl	74_37	-1	known	missense	c.1135	p.H379Y	1.000	pfam_Kelch_1,smart_Kelch_1,pirsf_Kelch-like_gigaxonin	pfam_Kelch_1,pfam_BACK,pfam_Kelch_2,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like	-	no_errors	KLHL8	HGNC	ENSG00000145332				44	0	0.00	26	2	7.14
KLK2	0	genome.wustl.edu	37	19	51379818	51379818	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	51379818	51379818	G	A	SNP	KLK2	ENST00000595316	human	ensembl	74_37	+1	known	missense	c.137	p.R46H	0.002	NULL	NULL	-	no_errors	KLK2	HGNC	ENSG00000167751	tier1	-	-	21	0	0.00	26	11	29.73
KMT2D	0	genome.wustl.edu	37	12	49433518	49433518	+	Nonsense_Mutation	SNP	T	T	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	12	49433518	49433518	T	A	SNP	KMT2D	ENST00000301067	human	ensembl	74_37	-1	known	nonsense	c.8035	p.K2679*	1.000	NULL	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2D	HGNC	ENSG00000167548				30	0	0.00	17	3	15.00
LDLRAP1	0	genome.wustl.edu	37	1	25881428	25881428	+	Frame_Shift_Del	DEL	C	C	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	25881428	25881428	C	-	DEL	LDLRAP1	ENST00000374338	human	ensembl	74_37	+1	known	frame_shift_del	c.309	p.T104fs	0.996	pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pfscan_PTB/PI_dom	pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pfscan_PTB/PI_dom	-	no_errors	LDLRAP1	HGNC	ENSG00000157978	tier1			35	0	0.00	11	2	15.38
LOC101929290	0	genome.wustl.edu	37	8	11177526	11177526	+	RNA	DEL	T	T	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	11177526	11177526	T	-	DEL	LOC101929290	ENST00000498997	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	AF131216.6	Clone_based_vega_gene	ENSG00000246477	tier1			15	0	0.00	9	4	30.77
LRP8	0	genome.wustl.edu	37	1	53715213	53715214	+	Frame_Shift_Ins	INS	-	-	AA			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	53715213	53715214	-	AA	INS	LRP8	ENST00000306052	human	ensembl	74_37	-1	known	frame_shift_ins	c.2692_2691	p.D897fs	1.000:1.000	NULL	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,pfam_EGF-like_Ca-bd_dom,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP8	HGNC	ENSG00000157193	tier1			31	0	0.00	25	10	28.57
LRRC66	0	genome.wustl.edu	37	4	52862198	52862198	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	52862198	52862198	C	T	SNP	LRRC66	ENST00000343457	human	ensembl	74_37	-1	known	silent	c.990	p.T330	0.000	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC66	HGNC	ENSG00000188993				15	0	0.00	21	2	8.70
MAP3K2	0	genome.wustl.edu	37	2	128075818	128075818	+	Missense_Mutation	SNP	T	T	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	128075818	128075818	T	A	SNP	MAP3K2	ENST00000344908	human	ensembl	74_37	-1	known	missense	c.1121	p.Y374F	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_OPR_PB1,superfamily_Kinase-like_dom,smart_OPR_PB1,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP3K2	HGNC	ENSG00000169967	tier1	-	-	57	0	0.00	22	16	42.11
MAP3K4	0	genome.wustl.edu	37	6	161508782	161508782	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	161508782	161508782	G	T	SNP	MAP3K4	ENST00000392142	human	ensembl	74_37	+1	known	missense	c.2619	p.K873N	0.008	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP3K4	HGNC	ENSG00000085511	tier1	-	-	37	0	0.00	37	4	9.76
MAP4	0	genome.wustl.edu	37	3	47963311	47963311	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	47963311	47963311	G	A	SNP	MAP4	ENST00000360240	human	ensembl	74_37	-1	known	missense	c.473	p.A158V	0.012	NULL	pfam_MAP_tubulin-bd_rpt	-	no_errors	MAP4	HGNC	ENSG00000047849				37	0	0.00	30	2	6.25
MCHR1	0	genome.wustl.edu	37	22	41077184	41077184	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	22	41077184	41077184	G	A	SNP	MCHR1	ENST00000249016	human	ensembl	74_37	+1	known	missense	c.521	p.G174D	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_MCH1_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_MCH1_rcpt,prints_MCH_rcpt,prints_GPCR_Rhodpsn	-	no_errors	MCHR1	HGNC	ENSG00000128285	tier1	-	-	48	0	0.00	24	13	35.14
MCM3AP	0	genome.wustl.edu	37	21	47703581	47703581	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	21	47703581	47703581	C	T	SNP	MCM3AP	ENST00000291688	human	ensembl	74_37	-1	known	missense	c.1391	p.R464H	0.980	NULL	pfam_SAC3/GANP/Nin1/mts3/eIF-3-p25	-	no_errors	MCM3AP	HGNC	ENSG00000160294				38	0	0.00	34	2	5.56
MDN1	0	genome.wustl.edu	37	6	90393001	90393001	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	90393001	90393001	G	-	DEL	MDN1	ENST00000369393	human	ensembl	74_37	-1	known	frame_shift_del	c.11952	p.C3985fs	0.990	pirsf_Midasin	pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-3,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_AAA+_ATPase,smart_VWF_A,pirsf_Midasin,pfscan_VWF_A	-	no_errors	MDN1	HGNC	ENSG00000112159	tier1			33	0	0.00	27	2	6.90
MIR99A	0	genome.wustl.edu	37	21	17911455	17911455	+	RNA	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	21	17911455	17911455	G	A	SNP	MIR99A	ENST00000384906	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.969	-	-	-	no_errors	MIR99A	HGNC	ENSG00000207638				52	0	0.00	55	4	6.78
MKLN1	0	genome.wustl.edu	37	7	131172442	131172442	+	Missense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	131172442	131172442	C	A	SNP	MKLN1	ENST00000352689	human	ensembl	74_37	+1	known	missense	c.2163	p.S721R	1.000	NULL	pfam_Muskelin_N,pfam_Kelch_1,pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_LisH_dimerisation,pfscan_LisH_dimerisation,pfscan_CTLH_C	-	no_errors	MKLN1	HGNC	ENSG00000128585	tier1	-	-	70	0	0.00	44	4	8.33
MLH3	0	genome.wustl.edu	37	14	75513750	75513750	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	14	75513750	75513750	G	T	SNP	MLH3	ENST00000355774	human	ensembl	74_37	-1	known	missense	c.2609	p.S870Y	0.094	NULL	pfam_MutL_C,pfam_DNA_mismatch_repair_C,pfam_HATPase_ATP-bd,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,superfamily_WW_dom,smart_MutL_C	-	no_errors	MLH3	HGNC	ENSG00000119684	tier1	-	-	28	0	0.00	17	3	15.00
MOG	0	genome.wustl.edu	37	6	29627100	29627100	+	Splice_Site	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	29627100	29627100	G	T	SNP	MOG	ENST00000376903	human	ensembl	74_37	+1	known	splice_site	c.89-1	e2-1	0.998	-	-	-	no_errors	MOG	HGNC	ENSG00000204655	tier1	-	-	29	0	0.00	18	3	14.29
MROH2B	0	genome.wustl.edu	37	5	41051168	41051168	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	41051168	41051168	G	T	SNP	MROH2B	ENST00000399564	human	ensembl	74_37	-1	known	missense	c.1255	p.H419N	0.000	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	MROH2B	HGNC	ENSG00000171495	tier1	-	-	56	0	0.00	29	19	39.58
MTM1	0	genome.wustl.edu	37	X	149818273	149818273	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	X	149818273	149818273	C	T	SNP	MTM1	ENST00000370396	human	ensembl	74_37	+1	known	missense	c.952	p.R318W	1.000	NULL	pfam_Myotubularin-like_Pase_dom,pfam_GRAM,smart_GRAM,smart_Tyr_Pase_cat,pfscan_Tyr/Dual-sp_Pase	-	no_errors	MTM1	HGNC	ENSG00000171100	tier1	-	-	38	0	0.00	69	5	6.76
MUC5B	0	genome.wustl.edu	37	11	1265736	1265736	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	1265736	1265736	C	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.7635	p.S2545	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	-	-	33	0	0.00	11	7	38.89
MUC6	0	genome.wustl.edu	37	11	1017187	1017187	+	Missense_Mutation	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	1017187	1017187	T	C	SNP	MUC6	ENST00000421673	human	ensembl	74_37	-1	known	missense	c.5614	p.M1872V	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_Cys_knot_C,pfscan_Cys_knot_C	-	no_errors	MUC6	HGNC	ENSG00000184956	tier1	-	-	455	0	0.00	296	16	5.11
MYO1B	0	genome.wustl.edu	37	2	192280957	192280957	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	192280957	192280957	G	T	SNP	MYO1B	ENST00000304164	human	ensembl	74_37	+1	known	missense	c.3276	p.E1092D	0.998	pfam_Myosin_tail_2	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO1B	HGNC	ENSG00000128641	tier1	-	-	51	0	0.00	23	16	41.03
MYO1F	0	genome.wustl.edu	37	19	8587367	8587367	+	Missense_Mutation	SNP	C	C	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	8587367	8587367	C	G	SNP	MYO1F	ENST00000338257	human	ensembl	74_37	-1	known	missense	c.3114	p.Q1038H	1.000	superfamily_SH3_domain	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,pfam_SH3_domain,pfam_SH3_2,superfamily_P-loop_NTPase,superfamily_SH3_domain,smart_Myosin_head_motor_dom,smart_SH3_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_SH3_domain,prints_Myosin_head_motor_dom,prints_SH3_domain	-	no_errors	MYO1F	HGNC	ENSG00000142347	tier1	-	-	46	0	0.00	26	15	36.59
MYO1G	0	genome.wustl.edu	37	7	45015193	45015193	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	45015193	45015193	G	T	SNP	MYO1G	ENST00000258787	human	ensembl	74_37	-1	known	missense	c.454	p.R152S	1.000	pfam_Myosin_head_motor_dom,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO1G	HGNC	ENSG00000136286	tier1	-	-	41	0	0.00	25	4	13.79
NAPRT1	0	genome.wustl.edu	37	8	144659490	144659491	+	Frame_Shift_Ins	INS	-	-	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	144659490	144659491	-	T	INS	NAPRT1	ENST00000276844	human	ensembl	74_37	-1	known	frame_shift_ins	c.517_516	p.A172fs	0.971:0.015	pfam_Nic_PRibTrfase-Fam,superfamily_Quinolinate_PRibosylTrfase_C,pirsf_Nic_PRibTrfase-Fam,tigrfam_Nic_PRibTrfase_pncB	pfam_Nic_PRibTrfase-Fam,superfamily_Quinolinate_PRibosylTrfase_C,pirsf_Nic_PRibTrfase-Fam,tigrfam_Nic_PRibTrfase_pncB	-	no_errors	NAPRT1	HGNC	ENSG00000147813	tier1			42	0	0.00	22	4	15.38
NAPRT1	0	genome.wustl.edu	37	8	144659491	144659492	+	Frame_Shift_Ins	INS	-	-	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	144659491	144659492	-	G	INS	NAPRT1	ENST00000276844	human	ensembl	74_37	-1	known	frame_shift_ins	c.516_515	p.A173fs	0.015:0.852	pfam_Nic_PRibTrfase-Fam,superfamily_Quinolinate_PRibosylTrfase_C,pirsf_Nic_PRibTrfase-Fam,tigrfam_Nic_PRibTrfase_pncB	pfam_Nic_PRibTrfase-Fam,superfamily_Quinolinate_PRibosylTrfase_C,pirsf_Nic_PRibTrfase-Fam,tigrfam_Nic_PRibTrfase_pncB	-	no_errors	NAPRT1	HGNC	ENSG00000147813	tier1			42	0	0.00	22	4	15.38
NBPF10	0	genome.wustl.edu	37	1	145304458	145304458	+	Missense_Mutation	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	145304458	145304458	A	G	SNP	NBPF10	ENST00000342960	human	ensembl	74_37	+1	known	missense	c.1391	p.K464R	0.001	pfam_NBPF_dom	pfam_NBPF_dom	-	no_errors	NBPF10	HGNC	ENSG00000163386	tier1	-	-	305	0	0.00	361	91	20.09
NCOA3	0	genome.wustl.edu	37	20	46277770	46277770	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	20	46277770	46277770	G	A	SNP	NCOA3	ENST00000371998	human	ensembl	74_37	+1	known	missense	c.3568	p.A1190T	1.000	pirsf_Nuclear_rcpt_coactivator	pfam_Nuc_rcpt_coact_Ncoa-typ,pfam_SRC-1,pfam_PAS_fold,superfamily_PAS,superfamily_Nuc_rcpt_coact,superfamily_bHLH_dom,smart_bHLH_dom,smart_PAS,pirsf_Nuclear_rcpt_coactivator,pfscan_PAS,pfscan_bHLH_dom	-	no_errors	NCOA3	HGNC	ENSG00000124151				26	0	0.00	32	2	5.88
NET1	0	genome.wustl.edu	37	10	5494811	5494811	+	RNA	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	5494811	5494811	A	-	DEL	NET1	ENST00000486354	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	NET1	HGNC	ENSG00000173848	tier1			37	0	0.00	31	4	11.43
NFE2L2	0	genome.wustl.edu	37	2	178098957	178098957	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	178098957	178098957	G	A	SNP	NFE2L2	ENST00000397062	human	ensembl	74_37	-1	known	missense	c.88	p.L30F	1.000	NULL	pfam_bZIP,superfamily_TF_DNA-bd,superfamily_Serpin_dom,smart_bZIP,pfscan_bZIP	-	no_errors	NFE2L2	HGNC	ENSG00000116044				56	0	0.00	41	13	24.07
NIT2	0	genome.wustl.edu	37	3	100058768	100058768	+	Missense_Mutation	SNP	A	A	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	100058768	100058768	A	T	SNP	NIT2	ENST00000394140	human	ensembl	74_37	+1	known	missense	c.236	p.Y79F	1.000	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	pfam_C-N_Hydrolase,superfamily_C-N_Hydrolase,pfscan_C-N_Hydrolase	-	no_errors	NIT2	HGNC	ENSG00000114021	tier1	-	-	66	0	0.00	62	54	46.55
NTRK2	0	genome.wustl.edu	37	9	87635245	87635245	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	87635245	87635245	G	A	SNP	NTRK2	ENST00000277120	human	ensembl	74_37	+1	known	missense	c.2297	p.G766D	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_LRR-contain_N,superfamily_Kinase-like_dom,smart_LRR-contain_N,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_Tyr_kinase_NGF_rcpt,prints_Tyr_kin_neurotrophic_rcpt_2	-	no_errors	NTRK2	HGNC	ENSG00000148053				28	0	0.00	43	3	6.52
NUP205	0	genome.wustl.edu	37	7	135261145	135261145	+	Silent	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	135261145	135261145	A	G	SNP	NUP205	ENST00000285968	human	ensembl	74_37	+1	known	silent	c.471	p.T157	0.116	pfam_Nup186/Nup192/Nup205	pfam_Nup186/Nup192/Nup205	-	no_errors	NUP205	HGNC	ENSG00000155561				73	0	0.00	68	4	5.56
OR5H6	0	genome.wustl.edu	37	3	97983602	97983602	+	Silent	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	97983602	97983602	T	C	SNP	OR5H6	ENST00000383696	human	ensembl	74_37	+1	known	silent	c.474	p.I158	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5H6	HGNC	ENSG00000230301	tier1	rs75354046	-	77	0	0.00	134	10	6.94
PCNXL4	0	genome.wustl.edu	37	14	60592519	60592519	+	Missense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	14	60592519	60592519	C	A	SNP	PCNXL4	ENST00000404681	human	ensembl	74_37	+1	known	missense	c.3245	p.S1082Y	1.000	pfam_Pecanex	pfam_Pecanex	-	no_errors	PCNXL4	HGNC	ENSG00000126773				43	0	0.00	20	2	9.09
POLN	0	genome.wustl.edu	37	4	2073729	2073729	+	RNA	DEL	C	C	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	2073729	2073729	C	-	DEL	POLN	ENST00000503371	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	POLN	HGNC	ENSG00000130997	tier1			67	0	0.00	36	2	5.26
POLR2J3	0	genome.wustl.edu	37	7	102182057	102182057	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	102182057	102182057	C	T	SNP	POLR2J3	ENST00000486319	human	ensembl	74_37	-1	known	missense	c.280	p.G94R	0.986	NULL	superfamily_RBP11-like_dimer	-	no_errors	POLR2J3	HGNC	ENSG00000168255	tier1	-	-	59	0	0.00	35	6	14.29
PPP1R10	0	genome.wustl.edu	37	6	30573700	30573700	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	30573700	30573700	G	A	SNP	PPP1R10	ENST00000376511	human	ensembl	74_37	-1	known	missense	c.853	p.P285S	1.000	NULL	pfam_TFIIS_N,pfam_Znf_CCCH,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub,smart_Znf_CCCH	-	no_errors	PPP1R10	HGNC	ENSG00000204569				94	0	0.00	76	4	5.00
PRKDC	0	genome.wustl.edu	37	8	48733437	48733437	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	48733437	48733437	G	A	SNP	PRKDC	ENST00000314191	human	ensembl	74_37	-1	known	missense	c.9176	p.S3059F	0.998	pfam_PIK-rel_kinase_FAT,pfscan_PIK_FAT	pfam_NUC194,pfam_PIK-rel_kinase_FAT,pfam_PI3/4_kinase_cat_dom,pfam_FATC,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_PI3/4_kinase_cat_dom,pfscan_PIK_FAT,pfscan_FATC,pfscan_PI3/4_kinase_cat_dom	-	no_errors	PRKDC	HGNC	ENSG00000253729	tier1	-	-	58	0	0.00	60	24	28.57
PRMT2	0	genome.wustl.edu	37	21	48069656	48069656	+	Missense_Mutation	SNP	G	G	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	21	48069656	48069656	G	C	SNP	PRMT2	ENST00000397628	human	ensembl	74_37	+1	putative	missense	c.659	p.R220T	0.747	NULL	pfam_SH3_domain,pfam_SH3_2,pfam_Small_mtfrase_dom,pfam_Ribosomal-L11_MeTrfase_PrmA,pfam_tRNA_Trfase_Trm5/Tyw2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain,prints_SH3_domain	-	no_errors	PRMT2	HGNC	ENSG00000160310	tier1	-	-	45	0	0.00	40	30	42.86
PRR3	0	genome.wustl.edu	37	6	30531428	30531428	+	RNA	DEL	T	T	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	30531428	30531428	T	-	DEL	PRR3	ENST00000481741	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	PRR3	HGNC	ENSG00000204576	tier1			27	0	0.00	24	3	11.11
PTER	0	genome.wustl.edu	37	10	16553247	16553247	+	Missense_Mutation	SNP	T	T	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	16553247	16553247	T	G	SNP	PTER	ENST00000298942	human	ensembl	74_37	+1	known	missense	c.1042	p.F348V	1.000	NULL	pfam_Aryldialkylphosphatase,pfam_TatD_family	-	no_errors	PTER	HGNC	ENSG00000165983	tier1	-	-	41	0	0.00	18	21	53.85
PTPLA	0	genome.wustl.edu	37	10	17646048	17646049	+	Splice_Site	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	17646048	17646049	-	A	INS	PTPLA	ENST00000361271	human	ensembl	74_37	-1	known	splice_site_ins	c.258-3_258-2	e2-2	1.000:0.005	-	-	-	no_errors	PTPLA	HGNC	ENSG00000165996	tier1			30	0	0.00	25	2	7.41
PTPRQ	0	genome.wustl.edu	37	12	80982225	80982225	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	12	80982225	80982225	C	T	SNP	PTPRQ	ENST00000266688	human	ensembl	74_37	+1	known	missense	c.4591	p.P1531S	1.000	superfamily_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Tyr_Pase_rcpt/non-rcpt,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRQ	HGNC	ENSG00000139304	tier1	-	-	33	0	0.00	24	3	11.11
PTTG1IP	0	genome.wustl.edu	37	21	46276194	46276196	+	In_Frame_Del	DEL	GCA	GCA	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	GCA	GCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	21	46276194	46276196	GCA	-	DEL	PTTG1IP	ENST00000330938	human	ensembl	74_37	-1	known	in_frame_del	c.363_361	p.C121in_frame_del	1.000:1.000:1.000	NULL	smart_Plexin-like_fold	-	no_errors	PTTG1IP	HGNC	ENSG00000183255	tier1			40	0	0.00	42	3	6.67
PUM1	0	genome.wustl.edu	37	1	31418206	31418206	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	31418206	31418206	G	A	SNP	PUM1	ENST00000426105	human	ensembl	74_37	-1	known	missense	c.2981	p.A994V	1.000	superfamily_ARM-type_fold,smart_Pumilio_RNA-bd_rpt,pfscan_Pumilio_RNA-bd_rpt	pfam_Pumilio_RNA-bd_rpt,superfamily_ARM-type_fold,smart_Pumilio_RNA-bd_rpt,pfscan_Pumilio_RNA-bd_rpt	-	no_errors	PUM1	HGNC	ENSG00000134644				50	0	0.00	38	2	5.00
RAB32	0	genome.wustl.edu	37	6	146870631	146870632	+	Frame_Shift_Ins	INS	-	-	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	146870631	146870632	-	T	INS	RAB32	ENST00000367495	human	ensembl	74_37	+1	known	frame_shift_ins	c.282_283	p.Y94fs	0.036:0.999	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_Gtr1_RagA,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_Gtr1_RagA,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RAB32	HGNC	ENSG00000118508	tier1			86	0	0.00	49	24	32.88
RAB36	0	genome.wustl.edu	37	22	23503091	23503091	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	22	23503091	23503091	C	T	SNP	RAB36	ENST00000263116	human	ensembl	74_37	+1	known	silent	c.843	p.S281	1.000	pfam_Small_GTPase,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_Gtr1_RagA,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RAB36	HGNC	ENSG00000100228				38	0	0.00	29	3	9.38
RAB3C	0	genome.wustl.edu	37	5	58021834	58021834	+	Silent	SNP	A	A	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	58021834	58021834	A	C	SNP	RAB3C	ENST00000282878	human	ensembl	74_37	+1	known	silent	c.258	p.T86	1.000	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_Gtr1_RagA,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_Gtr1_RagA,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RAB3C	HGNC	ENSG00000152932	tier1	-	-	31	0	0.00	18	22	55.00
REV3L	0	genome.wustl.edu	37	6	111654555	111654555	+	Missense_Mutation	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	111654555	111654555	T	C	SNP	REV3L	ENST00000358835	human	ensembl	74_37	-1	known	missense	c.7696	p.M2566V	1.000	pfam_DNA-dir_DNA_pol_B_multi_dom,smart_DNA-dir_DNA_pol_B	pfam_DNA-dir_DNA_pol_B_multi_dom,pfam_DNA-dir_DNA_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_DNA-dir_DNA_pol_B,prints_DNA-dir_DNA_pol_B	-	no_errors	REV3L	HGNC	ENSG00000009413	tier1	-	-	53	0	0.00	40	15	27.27
RS1	0	genome.wustl.edu	37	X	18665389	18665389	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	X	18665389	18665389	C	T	SNP	RS1	ENST00000379984	human	ensembl	74_37	-1	known	missense	c.248	p.C83Y	1.000	pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	-	no_errors	RS1	HGNC	ENSG00000102104	tier1	-	-	44	0	0.00	31	4	11.43
S100PBP	0	genome.wustl.edu	37	1	33292385	33292385	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	33292385	33292385	C	T	SNP	S100PBP	ENST00000373475	human	ensembl	74_37	+1	known	missense	c.685	p.P229S	0.009	NULL	NULL	-	no_errors	S100PBP	HGNC	ENSG00000116497	tier1	-	-	29	0	0.00	27	4	12.90
SCAI	0	genome.wustl.edu	37	9	127765857	127765857	+	RNA	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	9	127765857	127765857	A	-	DEL	SCAI	ENST00000487795	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.025	-	-	-	no_errors	SCAI	HGNC	ENSG00000173611	tier1			24	0	0.00	47	4	7.84
SCD	0	genome.wustl.edu	37	10	102107836	102107838	+	In_Frame_Del	DEL	ACC	ACC	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	ACC	ACC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	10	102107836	102107838	ACC	-	DEL	SCD	ENST00000370355	human	ensembl	74_37	+1	known	in_frame_del	c.43_45	p.T18in_frame_del	0.998:0.990:0.094	NULL	pfam_Fatty_acid_desaturase-1,prints_Fatty_acid_desaturase-1_core	-	no_errors	SCD	HGNC	ENSG00000099194	tier1			20	0	0.00	25	2	7.41
SCN4A	0	genome.wustl.edu	37	17	62022996	62022996	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	62022996	62022996	C	T	SNP	SCN4A	ENST00000435607	human	ensembl	74_37	-1	known	silent	c.3444	p.V1148	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfscan_IQ_motif_EF-hand-BS,prints_Na_channel_a4su,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN4A	HGNC	ENSG00000007314	tier1	-	-	36	0	0.00	6	14	70.00
SEC14L1	0	genome.wustl.edu	37	17	75210142	75210142	+	RNA	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	75210142	75210142	G	A	SNP	SEC14L1	ENST00000588721	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.284	-	-	-	no_errors	SEC14L1	HGNC	ENSG00000129657	tier1	-	-	43	0	0.00	23	21	47.73
SENP6	0	genome.wustl.edu	37	6	76388386	76388386	+	Missense_Mutation	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	76388386	76388386	A	G	SNP	SENP6	ENST00000370014	human	ensembl	74_37	+1	known	missense	c.1936	p.I646V	0.988	NULL	pfam_Peptidase_C48,pfscan_Peptidase_C48	-	no_errors	SENP6	HGNC	ENSG00000112701	tier1	-	-	63	0	0.00	31	20	39.22
SLCO6A1	0	genome.wustl.edu	37	5	101735276	101735276	+	Silent	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	101735276	101735276	G	T	SNP	SLCO6A1	ENST00000379807	human	ensembl	74_37	-1	known	silent	c.1797	p.I599	0.000	pfam_OA_transporter,superfamily_MFS_dom_general_subst_transpt,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,tigrfam_OA_transporter	-	no_errors	SLCO6A1	HGNC	ENSG00000205359				48	0	0.00	44	3	6.38
SOGA2	0	genome.wustl.edu	37	18	8793003	8793004	+	Frame_Shift_Ins	INS	-	-	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	18	8793003	8793004	-	C	INS	SOGA2	ENST00000359865	human	ensembl	74_37	+1	known	frame_shift_ins	c.1895_1896	p.V635fs	0.026:0.015	NULL	pfam_SOGA	-	no_errors	SOGA2	HGNC	ENSG00000168502	tier1			24	0	0.00	23	12	34.29
SOWAHD	0	genome.wustl.edu	37	X	118893519	118893519	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	X	118893519	118893519	C	T	SNP	SOWAHD	ENST00000343905	human	ensembl	74_37	+1	known	missense	c.889	p.R297W	0.001	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	SOWAHD	HGNC	ENSG00000187808	tier1	-	-	17	0	0.00	24	10	29.41
SPATA16	0	genome.wustl.edu	37	3	172835311	172835311	+	Nonsense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	172835311	172835311	C	A	SNP	SPATA16	ENST00000351008	human	ensembl	74_37	-1	known	nonsense	c.211	p.E71*	1.000	NULL	NULL	-	no_errors	SPATA16	HGNC	ENSG00000144962	tier1	-	-	65	0	0.00	69	22	24.18
STAMBP	0	genome.wustl.edu	37	2	74072312	74072312	+	Missense_Mutation	SNP	T	T	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	74072312	74072312	T	C	SNP	STAMBP	ENST00000339566	human	ensembl	74_37	+1	known	missense	c.298	p.F100L	1.000	NULL	pfam_JAB_MPN_dom,smart_JAB_MPN_dom	-	no_errors	STAMBP	HGNC	ENSG00000124356	tier1	-	-	55	0	0.00	28	20	41.67
SYT11	0	genome.wustl.edu	37	1	155838231	155838231	+	Silent	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	155838231	155838231	G	T	SNP	SYT11	ENST00000368324	human	ensembl	74_37	+1	known	silent	c.510	p.P170	0.129	superfamily_C2_dom,prints_Synaptotagmin	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom,prints_Synaptotagmin	-	no_errors	SYT11	HGNC	ENSG00000132718				22	0	0.00	36	4	10.00
TAF1D	0	genome.wustl.edu	37	11	93466281	93466281	+	RNA	SNP	T	T	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	11	93466281	93466281	T	A	SNP	TAF1D	ENST00000530089	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TAF1D	HGNC	ENSG00000166012	tier1	-	-	86	0	0.00	39	31	44.29
TDRD3	0	genome.wustl.edu	37	13	61034813	61034813	+	RNA	SNP	T	T	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	13	61034813	61034813	T	G	SNP	TDRD3	ENST00000463109	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.274	-	-	-	no_errors	TDRD3	HGNC	ENSG00000083544	tier1	-	-	24	0	0.00	12	7	36.84
TGIF1	0	genome.wustl.edu	37	18	3456685	3456685	+	Missense_Mutation	SNP	A	A	G			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	18	3456685	3456685	A	G	SNP	TGIF1	ENST00000551402	human	ensembl	74_37	+1	putative	missense	c.350	p.K117R	0.000	NULL	superfamily_Homeodomain-like,smart_Homeobox_dom	-	no_errors	TGIF1	HGNC	ENSG00000177426				20	0	0.00	17	8	32.00
TJAP1	0	genome.wustl.edu	37	6	43469320	43469320	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	6	43469320	43469320	G	A	SNP	TJAP1	ENST00000372445	human	ensembl	74_37	+1	known	missense	c.185	p.R62H	1.000	NULL	NULL	-	no_errors	TJAP1	HGNC	ENSG00000137221	tier1	-	-	24	0	0.00	12	10	45.45
TP53	0	genome.wustl.edu	37	17	7578176	7578176	+	Splice_Site	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	17	7578176	7578176	C	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	splice_site	c.672+1	e5+1	1.000	-	-	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	44	0	0.00	7	27	79.41
TRMT10C	0	genome.wustl.edu	37	3	101284009	101284009	+	Frame_Shift_Del	DEL	A	A	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	3	101284009	101284009	A	-	DEL	TRMT10C	ENST00000309922	human	ensembl	74_37	+1	known	frame_shift_del	c.384	p.K131fs	0.514	NULL	pfam_tRNA_m1G_MeTrfase	-	no_errors	TRMT10C	HGNC	ENSG00000174173	tier1			18	0	0.00	28	3	9.68
TTC37	0	genome.wustl.edu	37	5	94803579	94803579	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	5	94803579	94803579	C	T	SNP	TTC37	ENST00000358746	human	ensembl	74_37	-1	known	silent	c.4611	p.E1537	1.000	NULL	pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom	-	no_errors	TTC37	HGNC	ENSG00000198677				22	0	0.00	32	2	5.88
TTN	0	genome.wustl.edu	37	2	179647001	179647001	+	Silent	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	2	179647001	179647001	G	A	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	silent	c.3318	p.G1106	0.021	pfam_Ig_I-set,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	rs141768043	-	30	0	0.00	23	14	37.84
UBR4	0	genome.wustl.edu	37	1	19487548	19487548	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	19487548	19487548	G	A	SNP	UBR4	ENST00000375267	human	ensembl	74_37	-1	known	missense	c.5269	p.R1757C	1.000	superfamily_ARM-type_fold	superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_Znf_N-recognin_met,pfscan_Znf_N-recognin	-	no_errors	UBR4	HGNC	ENSG00000127481				33	0	0.00	28	2	6.67
ULK3	0	genome.wustl.edu	37	15	75132906	75132906	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	15	75132906	75132906	G	-	DEL	ULK3	ENST00000440863	human	ensembl	74_37	-1	known	frame_shift_del	c.546	p.E183fs	0.002	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_MIT,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_MIT,pfscan_Prot_kinase_dom	-	no_errors	ULK3	HGNC	ENSG00000140474	tier1			18	0	0.00	17	2	10.53
UNC79	0	genome.wustl.edu	37	14	94155164	94155164	+	Frame_Shift_Del	DEL	C	C	-			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	14	94155164	94155164	C	-	DEL	UNC79	ENST00000553484	human	ensembl	74_37	+1	known	frame_shift_del	c.7246	p.S2418fs	1.000	NULL	superfamily_P-loop_NTPase,superfamily_ARM-type_fold	-	no_errors	UNC79	HGNC	ENSG00000133958	tier1			26	0	0.00	19	2	9.52
UTY	0	genome.wustl.edu	37	Y	15448217	15448218	+	Splice_Site	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	Y	15448217	15448218	0	A	INS	UTY	ENST00000382896	human	ensembl	74_37	-1	known	splice_site_ins	c.1906-3_1906-2	e17-2	0.999:0.923	-	-	-	no_errors	UTY	HGNC	ENSG00000183878				13	0	0.00	6	2	25.00
VN1R1	0	genome.wustl.edu	37	19	57967427	57967427	+	Missense_Mutation	SNP	T	T	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	57967427	57967427	T	A	SNP	VN1R1	ENST00000321039	human	ensembl	74_37	-1	known	missense	c.428	p.N143I	0.000	pfam_Vmron_rcpt_1,pfam_TAS2_rcpt,pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_Vmron_rcpt_1,pfam_TAS2_rcpt,pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Vmron_rcpt_1	-	no_errors	VN1R1	HGNC	ENSG00000178201	tier1	-	-	33	0	0.00	42	10	19.23
VPS13C	0	genome.wustl.edu	37	15	62147075	62147075	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	15	62147075	62147075	C	T	SNP	VPS13C	ENST00000261517	human	ensembl	74_37	-1	known	missense	c.11155	p.A3719T	0.997	NULL	pfam_VPSAP_dom,pfam_Autophagy-rel_C	-	no_errors	VPS13C	HGNC	ENSG00000129003	tier1	-	-	69	0	0.00	62	4	6.06
VWA8	0	genome.wustl.edu	37	13	42161713	42161713	+	Nonsense_Mutation	SNP	C	C	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	13	42161713	42161713	C	A	SNP	VWA8	ENST00000379310	human	ensembl	74_37	-1	known	nonsense	c.5206	p.E1736*	1.000	pfam_VWF_A,smart_VWF_A,pfscan_VWF_A	pfam_ATPase_dyneun-rel_AAA,pfam_VWF_A,superfamily_P-loop_NTPase,smart_AAA+_ATPase,smart_VWF_A,pfscan_VWF_A	-	no_errors	VWA8	HGNC	ENSG00000102763				65	0	0.00	48	4	7.69
VWF	0	genome.wustl.edu	37	12	6153592	6153592	+	Silent	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	12	6153592	6153592	G	T	SNP	VWF	ENST00000261405	human	ensembl	74_37	-1	known	silent	c.2307	p.P769	0.994	pirsf_VWF	pirsf_VWF,pfam_VWF_type-D,pfam_VWF_A,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_VWF_A,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_A,pfscan_VWF_C	-	no_errors	VWF	HGNC	ENSG00000110799	tier1	-	-	23	0	0.00	8	19	70.37
WNK1	0	genome.wustl.edu	37	12	970296	970297	+	Frame_Shift_Ins	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	12	970296	970297	-	A	INS	WNK1	ENST00000530271	human	ensembl	74_37	+1	known	frame_shift_ins	c.1738_1739	p.K584fs	1.000:1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Kinase_OSR1/WNK_CCT,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	WNK1	HGNC	ENSG00000060237	tier1			25	0	0.00	24	3	11.11
YTHDF3	0	genome.wustl.edu	37	8	64124416	64124417	+	RNA	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	8	64124416	64124417	-	A	INS	YTHDF3	ENST00000521674	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.016:0.010	-	-	-	no_errors	YTHDF3	HGNC	ENSG00000185728	tier1			31	0	0.00	40	7	14.89
ZBTB14	0	genome.wustl.edu	37	18	5291775	5291775	+	Nonsense_Mutation	SNP	A	A	C			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	18	5291775	5291775	A	C	SNP	ZBTB14	ENST00000357006	human	ensembl	74_37	-1	known	nonsense	c.432	p.Y144*	0.993	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB14	HGNC	ENSG00000198081	tier1	-	-	21	0	0.00	24	6	20.00
ZBTB7A	0	genome.wustl.edu	37	19	4054661	4054661	+	Silent	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	4054661	4054661	C	T	SNP	ZBTB7A	ENST00000322357	human	ensembl	74_37	-1	known	silent	c.570	p.A190	0.000	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB7A	HGNC	ENSG00000178951	tier1	-	-	169	0	0.00	61	41	40.20
ZNF439	0	genome.wustl.edu	37	19	11979137	11979137	+	Missense_Mutation	SNP	C	C	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	11979137	11979137	C	T	SNP	ZNF439	ENST00000304030	human	ensembl	74_37	+1	known	missense	c.1253	p.A418V	0.535	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF439	HGNC	ENSG00000171291	tier1	-	-	60	0	0.00	62	5	7.46
ZNF678	0	genome.wustl.edu	37	1	227842427	227842427	+	Missense_Mutation	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	1	227842427	227842427	G	A	SNP	ZNF678	ENST00000397097	human	ensembl	74_37	+1	known	missense	c.641	p.G214D	0.999	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF678	HGNC	ENSG00000181450				13	0	0.00	22	6	21.43
ZNF679	0	genome.wustl.edu	37	7	63726569	63726570	+	Frame_Shift_Ins	INS	-	-	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	63726569	63726570	-	A	INS	ZNF679	ENST00000255746	human	ensembl	74_37	+1	known	frame_shift_ins	c.558_559	p.Y188fs	0.332:0.014	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF679	HGNC	ENSG00000197123	tier1			80	0	0.00	50	19	27.54
ZNF732	0	genome.wustl.edu	37	4	265855	265855	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	4	265855	265855	G	T	SNP	ZNF732	ENST00000419098	human	ensembl	74_37	-1	known	missense	c.791	p.T264N	0.001	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF732	HGNC	ENSG00000186777	tier1	-	-	30	0	0.00	17	9	34.62
ZNF99	0	genome.wustl.edu	37	19	22939048	22939048	+	Missense_Mutation	SNP	G	G	T			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	19	22939048	22939048	G	T	SNP	ZNF99	ENST00000397104	human	ensembl	74_37	-1	known	missense	c.3073	p.L1025I	0.021	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF99	HGNC	ENSG00000213973				29	0	0.00	29	4	12.12
ZNHIT1	0	genome.wustl.edu	37	7	100867224	100867224	+	Silent	SNP	G	G	A			TCGA-IG-A625-01A-11D-A31U-09	TCGA-IG-A625-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	fff223fa-957e-4a24-a5b0-fd3f9efba397	e142853b-0d36-4f63-ba19-54b80ed65115	7	100867224	100867224	G	A	SNP	ZNHIT1	ENST00000305105	human	ensembl	74_37	+1	known	silent	c.450	p.L150	1.000	NULL	pfam_Znf_HIT,pfscan_Znf_HIT	-	no_errors	ZNHIT1	HGNC	ENSG00000106400	tier1	-	-	32	0	0.00	24	9	27.27
