Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
AACS	0	genome.wustl.edu	37	12	125591780	125591780	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	125591780	125591780	C	G	SNP	AACS	ENST00000316519	human	ensembl	74_37	+1	known	missense	c.881	p.T294R	0.994	pfam_AMP-dep_Synth/Lig,tigrfam_Acac_CoA_synth	pfam_AMP-dep_Synth/Lig,tigrfam_Acac_CoA_synth	-	no_errors	AACS	HGNC	ENSG00000081760	tier1	-	-	44	0	0.00	18	17	48.57
ACAA2	0	genome.wustl.edu	37	18	47311700	47311700	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	47311700	47311700	G	T	SNP	ACAA2	ENST00000285093	human	ensembl	74_37	-1	known	missense	c.976	p.Q326K	1.000	pfam_Thiolase_C,superfamily_Thiolase-like,pirsf_Thiolase,tigrfam_Thiolase	pfam_Thiolase_N,pfam_Thiolase_C,superfamily_Thiolase-like,pirsf_Thiolase,tigrfam_Thiolase	-	no_errors	ACAA2	HGNC	ENSG00000167315	tier1	-	-	17	0	0.00	17	7	29.17
ADCK5	0	genome.wustl.edu	37	8	145616197	145616197	+	Nonsense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	145616197	145616197	G	T	SNP	ADCK5	ENST00000308860	human	ensembl	74_37	+1	known	nonsense	c.484	p.E162*	0.998	NULL	pfam_UbiB_dom,superfamily_Kinase-like_dom	-	no_errors	ADCK5	HGNC	ENSG00000173137				36	0	0.00	33	2	5.71
ADCY9	0	genome.wustl.edu	37	16	4027490	4027490	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	4027490	4027490	G	T	SNP	ADCY9	ENST00000294016	human	ensembl	74_37	-1	known	missense	c.2821	p.P941T	0.999	NULL	pfam_A/G_cyclase,superfamily_A/G_cyclase,smart_A/G_cyclase,pfscan_A/G_cyclase	-	no_errors	ADCY9	HGNC	ENSG00000162104	tier1	-	-	42	0	0.00	43	4	8.51
AHNAK2	0	genome.wustl.edu	37	14	105406708	105406708	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	105406708	105406708	G	A	SNP	AHNAK2	ENST00000333244	human	ensembl	74_37	-1	known	missense	c.15080	p.A5027V	0.001	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHNAK2	HGNC	ENSG00000185567	tier1	-	-	40	0	0.00	51	4	7.27
AKAP3	0	genome.wustl.edu	37	12	4737281	4737281	+	Silent	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	4737281	4737281	G	T	SNP	AKAP3	ENST00000228850	human	ensembl	74_37	-1	known	silent	c.787	p.R263	0.007	pfam_AKAP_110_C,smart_AKAP_110	pfam_AKAP_110_C,pfam_RII_binding_1,smart_AKAP_110	-	no_errors	AKAP3	HGNC	ENSG00000111254	tier1	-	-	39	0	0.00	19	9	32.14
AKAP4	0	genome.wustl.edu	37	X	49958407	49958407	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	X	49958407	49958407	C	T	SNP	AKAP4	ENST00000358526	human	ensembl	74_37	-1	known	silent	c.957	p.Q319	0.261	pfam_AKAP_110_C,smart_AKAP_110	pfam_AKAP_110_C,pfam_RII_binding_1,smart_AKAP_110	-	no_errors	AKAP4	HGNC	ENSG00000147081	tier1	-	-	25	0	0.00	19	9	32.14
AMPH	0	genome.wustl.edu	37	7	38468255	38468255	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	38468255	38468255	G	A	SNP	AMPH	ENST00000471913	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AMPH	HGNC	ENSG00000078053	tier1	-	-	48	0	0.00	54	13	19.40
ANKRD31	0	genome.wustl.edu	37	5	74442625	74442625	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	74442625	74442625	G	C	SNP	ANKRD31	ENST00000274361	human	ensembl	74_37	-1	known	missense	c.2611	p.H871D	0.000	superfamily_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD31	HGNC	ENSG00000145700	tier1	-	-	59	0	0.00	78	23	22.77
ANKRD50	0	genome.wustl.edu	37	4	125591662	125591662	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	125591662	125591662	C	A	SNP	ANKRD50	ENST00000504087	human	ensembl	74_37	-1	known	missense	c.2770	p.G924W	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD50	HGNC	ENSG00000151458				35	0	0.00	38	2	5.00
ANO6	0	genome.wustl.edu	37	12	45741883	45741883	+	Missense_Mutation	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	45741883	45741883	A	G	SNP	ANO6	ENST00000425752	human	ensembl	74_37	+1	known	missense	c.418	p.M140V	1.000	NULL	pfam_Anoctamin	-	no_errors	ANO6	HGNC	ENSG00000177119	tier1	-	-	30	0	0.00	19	16	45.71
AOC2	0	genome.wustl.edu	37	17	40997280	40997280	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	40997280	40997280	C	T	SNP	AOC2	ENST00000253799	human	ensembl	74_37	+1	known	missense	c.637	p.R213C	0.000	pfam_Cu_amine_oxidase_N3,superfamily_Cu_amine_oxidase_N-reg,prints_Cu_amine_oxidase	pfam_Cu_amine_oxidase_C,pfam_Cu_amine_oxidase_N3,pfam_Cu_amine_oxidase_N2,superfamily_Cu_amine_oxidase_C,superfamily_Cu_amine_oxidase_N-reg,prints_Cu_amine_oxidase	-	no_errors	AOC2	HGNC	ENSG00000131480				12	0	0.00	26	2	7.14
APOL5	0	genome.wustl.edu	37	22	36122366	36122366	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	22	36122366	36122366	G	T	SNP	APOL5	ENST00000249044	human	ensembl	74_37	+1	known	missense	c.251	p.R84L	0.000	pfam_ApoL	pfam_ApoL	-	no_errors	APOL5	HGNC	ENSG00000128313				11	0	0.00	18	2	10.00
ASXL3	0	genome.wustl.edu	37	18	31319196	31319196	+	Nonsense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	31319196	31319196	G	T	SNP	ASXL3	ENST00000269197	human	ensembl	74_37	+1	known	nonsense	c.1828	p.E610*	1.000	NULL	superfamily_Znf_FYVE_PHD	-	no_errors	ASXL3	HGNC	ENSG00000141431	tier1	-	-	14	0	0.00	13	9	40.91
ATCAY	0	genome.wustl.edu	37	19	3902495	3902495	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	3902495	3902495	G	C	SNP	ATCAY	ENST00000301260	human	ensembl	74_37	+1	known	missense	c.88	p.E30Q	1.000	NULL	pfam_Bcl2-/adenovirus-E1B,pfam_CRAL-TRIO_dom,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom	-	no_errors	ATCAY	HGNC	ENSG00000167654				29	0	0.00	29	4	12.12
ATF7IP2	0	genome.wustl.edu	37	16	10567798	10567798	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	10567798	10567798	G	T	SNP	ATF7IP2	ENST00000356427	human	ensembl	74_37	+1	known	missense	c.1501	p.D501Y	0.413	NULL	superfamily_Fibronectin_type3	-	no_errors	ATF7IP2	HGNC	ENSG00000166669	tier1	-	-	64	0	0.00	59	4	6.35
ATG2B	0	genome.wustl.edu	37	14	96752109	96752109	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	96752109	96752109	G	A	SNP	ATG2B	ENST00000359933	human	ensembl	74_37	-1	known	missense	c.6220	p.R2074C	1.000	pfam_Autophagy-rel_C	pfam_Autophagy-rel_C	-	no_errors	ATG2B	HGNC	ENSG00000066739	tier1	-	-	15	0	0.00	13	13	50.00
ATP5J2-PTCD1	0	genome.wustl.edu	37	7	99021462	99021462	+	Frame_Shift_Del	DEL	G	G	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	99021462	99021462	G	0	DEL	ATP5J2-PTCD1	ENST00000413834	human	ensembl	74_37	-1	known	frame_shift_del	c.2003	p.P668fs	0.938	NULL	pfam_Pentatricopeptide_repeat,pfam_F1F0-ATPsyn_F_prd,tigrfam_Pentatricopeptide_repeat	-	no_errors	ATP5J2-PTCD1	HGNC	ENSG00000248919				59	0	0.00	89	8	8.25
ATP9A	0	genome.wustl.edu	37	20	50244141	50244141	+	Nonsense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	50244141	50244141	C	A	SNP	ATP9A	ENST00000338821	human	ensembl	74_37	-1	known	nonsense	c.1843	p.E615*	1.000	pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP9A	HGNC	ENSG00000054793	tier1	-	-	42	0	0.00	44	4	8.33
AXIN2	0	genome.wustl.edu	37	17	63533733	63533735	+	In_Frame_Del	DEL	TGG	TGG	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	TGG	TGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	63533733	63533735	TGG	-	DEL	AXIN2	ENST00000307078	human	ensembl	74_37	-1	known	in_frame_del	c.1421_1419	p.H474in_frame_del	0.471:0.843:0.868	NULL	pfam_DIX,pfam_RGS_dom,pfam_Axin_b-cat-bd,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,smart_DIX,pfscan_DIX,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	AXIN2	HGNC	ENSG00000168646	tier1			24	0	0.00	24	2	7.69
B3GNT6	0	genome.wustl.edu	37	11	76751188	76751188	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	76751188	76751188	C	T	SNP	B3GNT6	ENST00000533140	human	ensembl	74_37	+1	known	missense	c.593	p.T198M	1.000	pfam_Glyco_trans_31	pfam_Glyco_trans_31	-	no_errors	B3GNT6	HGNC	ENSG00000198488	tier1	-	-	42	0	0.00	38	4	9.52
BCL9L	0	genome.wustl.edu	37	11	118772974	118772974	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	118772974	118772974	G	C	SNP	BCL9L	ENST00000334801	human	ensembl	74_37	-1	known	missense	c.1478	p.P493R	0.944	NULL	pfam_BCL9_beta-catenin-bd_dom	-	no_errors	BCL9L	HGNC	ENSG00000186174				23	0	0.00	20	4	16.67
BDP1	0	genome.wustl.edu	37	5	70810788	70810788	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	70810788	70810788	G	T	SNP	BDP1	ENST00000358731	human	ensembl	74_37	+1	known	missense	c.4488	p.M1496I	0.004	NULL	superfamily_Homeodomain-like,smart_SANT/Myb	-	no_errors	BDP1	HGNC	ENSG00000145734	tier1	-	-	18	0	0.00	22	7	24.14
BMS1P8	0	genome.wustl.edu	37	16	33490487	33490487	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	33490487	33490487	C	T	SNP	BMS1P8	ENST00000567036	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.985	-	-	-	no_errors	BMS1P8	HGNC	ENSG00000260518	tier1	-	-	19	0	0.00	14	9	39.13
BOC	0	genome.wustl.edu	37	3	112998245	112998245	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	112998245	112998245	G	T	SNP	BOC	ENST00000273395	human	ensembl	74_37	+1	known	missense	c.1966	p.A656S	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	BOC	HGNC	ENSG00000144857	tier1	-	-	30	0	0.00	28	4	12.50
BRI3	0	genome.wustl.edu	37	7	97921978	97921978	+	Silent	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	97921978	97921978	G	T	SNP	BRI3	ENST00000539286	human	ensembl	74_37	+1	known	silent	c.273	p.T91	0.000	NULL	pfam_Brain_I3	-	no_errors	BRI3	HGNC	ENSG00000164713	tier1	-	-	30	0	0.00	52	4	7.14
C10orf82	0	genome.wustl.edu	37	10	118424288	118424288	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	118424288	118424288	G	C	SNP	C10orf82	ENST00000588184	human	ensembl	74_37	-1	known	missense	c.445	p.L149V	0.066	NULL	NULL	-	no_errors	C10orf82	HGNC	ENSG00000165863	tier1	-	-	38	0	0.00	45	11	19.64
C17orf112	0	genome.wustl.edu	37	17	51063835	51063835	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	51063835	51063835	C	T	SNP	C17orf112	ENST00000441889	human	ensembl	74_37	+1	putative	silent	c.79	p.L27	0.016	NULL	NULL	-	no_errors	C17orf112	HGNC	ENSG00000227011	tier1	-	-	32	0	0.00	29	18	38.30
C1orf65	0	genome.wustl.edu	37	1	223568089	223568089	+	Silent	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	223568089	223568089	G	C	SNP	C1orf65	ENST00000366875	human	ensembl	74_37	+1	known	silent	c.1272	p.L424	0.001	NULL	NULL	-	no_errors	C1orf65	HGNC	ENSG00000178395	tier1	-	-	9	0	0.00	15	4	21.05
C4orf22	0	genome.wustl.edu	37	4	81504291	81504291	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	81504291	81504291	C	T	SNP	C4orf22	ENST00000508675	human	ensembl	74_37	+1	known	missense	c.287	p.T96M	1.000	NULL	NULL	-	no_errors	C4orf22	HGNC	ENSG00000197826				38	0	0.00	28	2	6.67
CACNA1C	0	genome.wustl.edu	37	12	2690840	2690840	+	Silent	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	2690840	2690840	C	G	SNP	CACNA1C	ENST00000399634	human	ensembl	74_37	+1	known	silent	c.1980	p.L660	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCC_L_a1csu,prints_VDCCAlpha1,prints_VDCC_L_a1su	-	no_errors	CACNA1C	HGNC	ENSG00000151067	tier1	-	-	71	0	0.00	46	28	37.84
CAMSAP1	0	genome.wustl.edu	37	9	138703425	138703425	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	138703425	138703425	G	A	SNP	CAMSAP1	ENST00000409386	human	ensembl	74_37	-1	known	silent	c.4572	p.I1524	1.000	pfam_CKK_domain,superfamily_PRC_barrel-like	pfam_CKK_domain,pfam_CAMSAP_CH,pfam_CH-domain,superfamily_PRC_barrel-like,superfamily_CH-domain	-	no_errors	CAMSAP1	HGNC	ENSG00000130559				41	0	0.00	29	3	9.38
CAPN6	0	genome.wustl.edu	37	X	110489963	110489963	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	X	110489963	110489963	C	T	SNP	CAPN6	ENST00000324068	human	ensembl	74_37	-1	known	missense	c.1768	p.D590N	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom	pfam_Peptidase_C2_calpain_cat,pfam_Calpain_domain_III,pfam_C2_dom,superfamily_Calpain_domain_III,superfamily_C2_dom,smart_Peptidase_C2_calpain_cat,smart_Calpain_III,smart_C2_dom,pfscan_Peptidase_C2_calpain_cat,prints_Calpain_cysteine_protease	-	no_errors	CAPN6	HGNC	ENSG00000077274				9	0	0.00	8	3	27.27
CASP14	0	genome.wustl.edu	37	19	15164590	15164590	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	15164590	15164590	G	T	SNP	CASP14	ENST00000221740	human	ensembl	74_37	+1	known	missense	c.224	p.R75L	0.201	pfam_Pept_C14_caspase,smart_Pept_C14A_p45_core,pfscan_Pept_C14_ICE_p20	pfam_Pept_C14_caspase,smart_Pept_C14A_p45_core,pfscan_Pept_C14_p10,pfscan_Pept_C14_ICE_p20,prints_Pept_C14A_p45_core	-	no_errors	CASP14	HGNC	ENSG00000105141				38	0	0.00	31	2	6.06
CATSPERD	0	genome.wustl.edu	37	19	5724873	5724873	+	Silent	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	5724873	5724873	G	C	SNP	CATSPERD	ENST00000381624	human	ensembl	74_37	+1	known	silent	c.126	p.G42	0.995	NULL	superfamily_WD40_repeat_dom	-	no_errors	CATSPERD	HGNC	ENSG00000174898	tier1	-	-	46	0	0.00	53	7	11.67
CCDC148	0	genome.wustl.edu	37	2	159107284	159107284	+	Frame_Shift_Del	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	159107284	159107284	T	-	DEL	CCDC148	ENST00000283233	human	ensembl	74_37	-1	known	frame_shift_del	c.1251	p.I418fs	0.032	NULL	NULL	-	no_errors	CCDC148	HGNC	ENSG00000153237	tier1			26	0	0.00	23	2	8.00
CD247	0	genome.wustl.edu	37	1	167404209	167404210	+	RNA	INS	-	-	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	167404209	167404210	-	T	INS	CD247	ENST00000483825	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	CD247	HGNC	ENSG00000198821	tier1			19	0	0.00	19	4	17.39
CDC73	0	genome.wustl.edu	37	1	193218912	193218912	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	193218912	193218912	G	T	SNP	CDC73	ENST00000367435	human	ensembl	74_37	+1	known	missense	c.1470	p.Q490H	1.000	pfam_RNA_pol_access_fac_Cdc73	pfam_RNA_pol_access_fac_Cdc73	-	no_errors	CDC73	HGNC	ENSG00000134371				56	0	0.00	66	4	5.71
CDH22	0	genome.wustl.edu	37	20	44815563	44815563	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	44815563	44815563	C	A	SNP	CDH22	ENST00000372262	human	ensembl	74_37	-1	known	missense	c.1447	p.A483S	0.996	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,superfamily_MFS_dom_general_subst_transpt,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH22	HGNC	ENSG00000149654				38	0	0.00	30	2	6.25
CDH6	0	genome.wustl.edu	37	5	31323263	31323263	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	31323263	31323263	G	A	SNP	CDH6	ENST00000265071	human	ensembl	74_37	+1	known	missense	c.2221	p.E741K	1.000	pfam_Cadherin_cytoplasmic-dom	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH6	HGNC	ENSG00000113361	tier1	-	-	33	0	0.00	22	9	29.03
CEACAM8	0	genome.wustl.edu	37	19	43087409	43087409	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	43087409	43087409	C	T	SNP	CEACAM8	ENST00000244336	human	ensembl	74_37	-1	known	missense	c.1039	p.A347T	0.007	NULL	pfam_Ig_V-set,pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	CEACAM8	HGNC	ENSG00000124469	tier1	-	-	38	0	0.00	35	4	10.26
CHD7	0	genome.wustl.edu	37	8	61777889	61777889	+	Silent	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	61777889	61777889	C	G	SNP	CHD7	ENST00000423902	human	ensembl	74_37	+1	known	silent	c.8391	p.P2797	1.000	NULL	pfam_SNF2_N,pfam_BRK_domain,pfam_Chromo_domain,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,smart_BRK_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow	-	no_errors	CHD7	HGNC	ENSG00000171316	tier1	-	-	18	0	0.00	11	6	35.29
CHPF2	0	genome.wustl.edu	37	7	150935679	150935679	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	150935679	150935679	G	A	SNP	CHPF2	ENST00000035307	human	ensembl	74_37	+1	known	missense	c.2231	p.R744H	1.000	pfam_Chond_GalNAc	pfam_Chond_GalNAc,pfam_Fringe-like	-	no_errors	CHPF2	HGNC	ENSG00000033100				24	0	0.00	22	3	12.00
CHRNB3	0	genome.wustl.edu	37	8	42587155	42587155	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	42587155	42587155	C	A	SNP	CHRNB3	ENST00000289957	human	ensembl	74_37	+1	known	missense	c.705	p.F235L	1.000	superfamily_Neurotrans-gated_channel_TM,prints_Neur_channel,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_Nicotinic_acetylcholine_rcpt,prints_Neur_channel,tigrfam_Neur_channel	-	no_errors	CHRNB3	HGNC	ENSG00000147432	tier1	-	-	60	0	0.00	280	24	7.82
CHST13	0	genome.wustl.edu	37	3	126261328	126261328	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	126261328	126261328	C	T	SNP	CHST13	ENST00000319340	human	ensembl	74_37	+1	known	silent	c.933	p.I311	1.000	pfam_Sulfotransferase	pfam_Sulfotransferase	-	no_errors	CHST13	HGNC	ENSG00000180767	tier1	-	-	23	0	0.00	41	6	12.77
CLASP2	0	genome.wustl.edu	37	3	33602361	33602361	+	Frame_Shift_Del	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	33602361	33602361	T	-	DEL	CLASP2	ENST00000399362	human	ensembl	74_37	-1	known	frame_shift_del	c.2890	p.M964fs	1.000	superfamily_ARM-type_fold	pfam_CLASP_N_dom,pfam_HEAT,superfamily_ARM-type_fold,pfscan_HEAT_type_2	-	no_errors	CLASP2	HGNC	ENSG00000163539	tier1			60	0	0.00	30	2	6.25
CLK1	0	genome.wustl.edu	37	2	201719347	201719347	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	201719347	201719347	C	G	SNP	CLK1	ENST00000321356	human	ensembl	74_37	-1	known	missense	c.1212	p.Q404H	1.000	pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CLK1	HGNC	ENSG00000013441	tier1	-	-	47	0	0.00	52	4	7.14
CLTCL1	0	genome.wustl.edu	37	22	19222152	19222152	+	Silent	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	22	19222152	19222152	C	A	SNP	CLTCL1	ENST00000263200	human	ensembl	74_37	-1	known	silent	c.1047	p.L349	1.000	pfam_Clathrin_H-chain_linker_core,superfamily_ARM-type_fold,pirsf_Clathrin_heavy_chain	pfam_Clathrin_H-chain/VPS_repeat,pfam_Clathrin_H-chain_propeller_rpt,pfam_Clathrin_H-chain_linker_core,superfamily_Clathrin_H-chain_propeller_N,superfamily_ARM-type_fold,smart_Clathrin_H-chain/VPS_repeat,pirsf_Clathrin_heavy_chain	-	no_errors	CLTCL1	HGNC	ENSG00000070371	tier1	-	-	30	0	0.00	47	4	7.84
COBL	0	genome.wustl.edu	37	7	51096641	51096641	+	Nonsense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	51096641	51096641	G	A	SNP	COBL	ENST00000395542	human	ensembl	74_37	-1	known	nonsense	c.2398	p.R800*	0.735	NULL	pfam_Cordon-bleu_ubiquitin_domain,pfam_WH2_dom,smart_WH2_dom,pfscan_WH2_dom	-	no_errors	COBL	HGNC	ENSG00000106078				18	0	0.00	48	3	5.88
COL11A1	0	genome.wustl.edu	37	1	103440440	103440440	+	Splice_Site	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	103440440	103440440	C	A	SNP	COL11A1	ENST00000358392	human	ensembl	74_37	-1	known	splice_site	c.2791-1	e36-1	1.000	-	-	-	no_errors	COL11A1	HGNC	ENSG00000060718				26	0	0.00	26	2	7.14
COL9A1	0	genome.wustl.edu	37	6	70978510	70978510	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	70978510	70978510	C	T	SNP	COL9A1	ENST00000357250	human	ensembl	74_37	-1	known	missense	c.1284	p.M428I	1.000	pfam_Collagen	pfam_Collagen,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G	-	no_errors	COL9A1	HGNC	ENSG00000112280				13	0	0.00	27	4	12.90
COPE	0	genome.wustl.edu	37	19	19030112	19030112	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	19030112	19030112	C	T	SNP	COPE	ENST00000262812	human	ensembl	74_37	-1	known	missense	c.46	p.V16I	0.981	pfam_Coatomer_esu,pirsf_Coatomer_esu	pfam_Coatomer_esu,pirsf_Coatomer_esu	-	no_errors	COPE	HGNC	ENSG00000105669				57	0	0.00	66	5	7.04
CRISP1	0	genome.wustl.edu	37	6	49825077	49825077	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	49825077	49825077	C	T	SNP	CRISP1	ENST00000335847	human	ensembl	74_37	-1	known	missense	c.37	p.A13T	0.002	superfamily_CAP_domain	pfam_Cysteine_rich_secretory,pfam_CAP_domain,superfamily_CAP_domain,smart_Allrgn_V5/Tpx1,prints_Allrgn_V5/Tpx1,prints_V5_allergen	-	no_errors	CRISP1	HGNC	ENSG00000124812	tier1	-	-	27	0	0.00	31	6	16.22
CSHL1	0	genome.wustl.edu	37	17	61987321	61987321	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	61987321	61987321	C	T	SNP	CSHL1	ENST00000561003	human	ensembl	74_37	-1	novel	silent	c.423	p.G141	0.005	NULL	pfam_Somatotropin,superfamily_4_helix_cytokine-like_core	-	no_errors	CSHL1	HGNC	ENSG00000204414	tier1	-	-	104	0	0.00	110	14	11.29
CXADRP3	0	genome.wustl.edu	37	18	14478264	14478264	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	14478264	14478264	G	A	SNP	CXADRP3	ENST00000581457	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.687	-	-	-	no_errors	CXADRP3	HGNC	ENSG00000265766				42	0	0.00	62	4	6.06
CYP4Z1	0	genome.wustl.edu	37	1	47534433	47534433	+	Missense_Mutation	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	47534433	47534433	A	G	SNP	CYP4Z1	ENST00000334194	human	ensembl	74_37	+1	known	missense	c.317	p.Q106R	0.447	pfam_Cyt_P450,superfamily_Cyt_P450	pfam_Cyt_P450,superfamily_Cyt_P450,prints_Cyt_P450_E_grp-I,prints_Cyt_P450_E_grp-IV,prints_Cyt_P450,prints_Cyt_P450_E_grp-II	-	no_errors	CYP4Z1	HGNC	ENSG00000186160	tier1	-	-	119	0	0.00	90	5	5.26
CYP4Z2P	0	genome.wustl.edu	37	1	47325354	47325354	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	47325354	47325354	G	A	SNP	CYP4Z2P	ENST00000505841	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.965	-	-	-	no_errors	CYP4Z2P	HGNC	ENSG00000154198				38	0	0.00	40	3	6.98
DACT2	0	genome.wustl.edu	37	6	168709234	168709234	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	168709234	168709234	G	A	SNP	DACT2	ENST00000366795	human	ensembl	74_37	-1	known	silent	c.1203	p.G401	0.000	NULL	NULL	-	no_errors	DACT2	HGNC	ENSG00000164488				44	0	0.00	21	4	16.00
DDX58	0	genome.wustl.edu	37	9	32459470	32459470	+	Nonsense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	32459470	32459470	G	A	SNP	DDX58	ENST00000379883	human	ensembl	74_37	-1	known	nonsense	c.2380	p.Q794*	0.141	superfamily_P-loop_NTPase	pfam_RIG-I_C-RD,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase/UvrB_dom,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_DEATH-like_dom,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DDX58	HGNC	ENSG00000107201	tier1	-	-	96	0	0.00	59	194	76.38
DMKN	0	genome.wustl.edu	37	19	35994206	35994206	+	RNA	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	35994206	35994206	T	-	DEL	DMKN	ENST00000474992	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	DMKN	HGNC	ENSG00000161249	tier1			97	0	0.00	84	33	28.21
DNAH3	0	genome.wustl.edu	37	16	21139069	21139069	+	Nonsense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	21139069	21139069	G	A	SNP	DNAH3	ENST00000261383	human	ensembl	74_37	-1	known	nonsense	c.1147	p.Q383*	0.030	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_Prefoldin,smart_AAA+_ATPase	-	no_errors	DNAH3	HGNC	ENSG00000158486	tier1	-	-	56	0	0.00	39	9	18.37
DNAH9	0	genome.wustl.edu	37	17	11622754	11622754	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	11622754	11622754	G	A	SNP	DNAH9	ENST00000262442	human	ensembl	74_37	+1	known	missense	c.5656	p.A1886T	1.000	superfamily_P-loop_NTPase,smart_AAA+_ATPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH9	HGNC	ENSG00000007174				45	0	0.00	26	2	7.14
DNAJB8	0	genome.wustl.edu	37	3	128181534	128181534	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	128181534	128181534	G	A	SNP	DNAJB8	ENST00000319153	human	ensembl	74_37	-1	known	silent	c.555	p.S185	0.997	NULL	pfam_DnaJ_domain,superfamily_DnaJ_domain,smart_DnaJ_domain,pfscan_DnaJ_domain,prints_DnaJ_domain	-	no_errors	DNAJB8	HGNC	ENSG00000179407	tier1	-	-	38	0	0.00	61	10	14.08
DNAJC15	0	genome.wustl.edu	37	13	43659934	43659934	+	Silent	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	13	43659934	43659934	A	G	SNP	DNAJC15	ENST00000379221	human	ensembl	74_37	+1	known	silent	c.342	p.T114	1.000	pfam_DnaJ_domain,superfamily_DnaJ_domain,smart_DnaJ_domain,pfscan_DnaJ_domain	pfam_DnaJ_domain,superfamily_DnaJ_domain,smart_DnaJ_domain,pfscan_DnaJ_domain	-	no_errors	DNAJC15	HGNC	ENSG00000120675	tier1	-	-	24	0	0.00	18	4	18.18
DPY19L2P2	0	genome.wustl.edu	37	7	102920598	102920598	+	RNA	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	102920598	102920598	A	G	SNP	DPY19L2P2	ENST00000312132	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.504	-	-	-	no_errors	DPY19L2P2	HGNC	ENSG00000170629	tier1	-	-	43	0	0.00	29	9	23.68
DSC3	0	genome.wustl.edu	37	18	28604445	28604445	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	28604445	28604445	C	T	SNP	DSC3	ENST00000360428	human	ensembl	74_37	-1	known	silent	c.645	p.A215	0.001	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,pfam_Cadherin_pro_dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin,prints_Cadherin/Desmocollin,prints_Desmosomal_cadherin	-	no_errors	DSC3	HGNC	ENSG00000134762				22	0	0.00	26	2	7.14
EFCAB6	0	genome.wustl.edu	37	22	44178174	44178174	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	22	44178174	44178174	C	T	SNP	EFCAB6	ENST00000262726	human	ensembl	74_37	-1	known	missense	c.25	p.D9N	0.001	NULL	pfam_EF_hand_Ca-bd_contain_6,smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	EFCAB6	HGNC	ENSG00000186976	tier1	-	-	57	0	0.00	49	16	24.62
EHBP1	0	genome.wustl.edu	37	2	63220713	63220713	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	63220713	63220713	C	T	SNP	EHBP1	ENST00000263991	human	ensembl	74_37	+1	known	missense	c.2995	p.R999C	1.000	NULL	pfam_DUF3585,pfam_CH-domain,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	EHBP1	HGNC	ENSG00000115504				11	0	0.00	14	2	12.50
ELAVL2	0	genome.wustl.edu	37	9	23731092	23731092	+	Nonsense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	23731092	23731092	G	T	SNP	ELAVL2	ENST00000380117	human	ensembl	74_37	-1	known	nonsense	c.261	p.Y87*	1.000	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,tigrfam_ELAD_HUD_SF	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom,prints_Hud_Sxl_RNA,tigrfam_ELAD_HUD_SF	-	no_errors	ELAVL2	HGNC	ENSG00000107105	tier1	-	-	66	0	0.00	31	4	11.43
ENSG00000215993	0	genome.wustl.edu	37	12	43685366	43685366	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	43685366	43685366	C	T	SNP	ENSG00000215993	ENST00000401174	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.001	-	-	-	no_errors	AC079603.1	Clone_based_ensembl_gene	ENSG00000215993	tier1	-	-	81	0	0.00	44	33	42.86
ENSG00000222031	0	genome.wustl.edu	37	2	151857851	151857851	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	151857851	151857851	G	A	SNP	ENSG00000222031	ENST00000409243	human	ensembl	74_37	-1	putative	silent	c.267	p.P89	0.001	NULL	NULL	-	no_errors	AC023469.1	Clone_based_vega_gene	ENSG00000222031	tier1	-	-	92	0	0.00	70	15	17.65
ENSG00000231817	0	genome.wustl.edu	37	13	47040077	47040077	+	RNA	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	13	47040077	47040077	A	G	SNP	ENSG00000231817	ENST00000594153	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.239	-	-	-	no_errors	RP11-189B4.6	Clone_based_vega_gene	ENSG00000231817	tier1	rs7319803	-	13	0	0.00	8	15	65.22
ENSG00000231817	0	genome.wustl.edu	37	13	47040087	47040087	+	RNA	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	13	47040087	47040087	C	A	SNP	ENSG00000231817	ENST00000594153	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.060	-	-	-	no_errors	RP11-189B4.6	Clone_based_vega_gene	ENSG00000231817	tier1	rs74755458	-	13	0	0.00	7	14	66.67
ENSG00000245156	0	genome.wustl.edu	37	11	66039507	66039507	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	66039507	66039507	G	A	SNP	ENSG00000245156	ENST00000501708	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-867G23.3	Clone_based_vega_gene	ENSG00000245156	tier1	-	-	9	0	0.00	10	4	28.57
ENSG00000261238	0	genome.wustl.edu	37	16	51183171	51183171	+	RNA	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	51183171	51183171	T	-	DEL	ENSG00000261238	ENST00000570060	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.007	-	-	-	no_errors	AC009166.5	Clone_based_vega_gene	ENSG00000261238	tier1			9	0	0.00	9	4	30.77
ENSG00000266527	0	genome.wustl.edu	37	17	26206315	26206315	+	RNA	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	26206315	26206315	A	G	SNP	ENSG00000266527	ENST00000581901	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.049	-	-	-	no_errors	RP11-138P22.1	Clone_based_vega_gene	ENSG00000266527	tier1	-	-	10	0	0.00	8	4	33.33
ENSG00000270726	0	genome.wustl.edu	37	X	155252801	155252801	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	X	155252801	155252801	G	A	SNP	ENSG00000270726	ENST00000285718	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	AJ271736.10	Clone_based_vega_gene	ENSG00000270726				107	0	0.00	60	4	6.25
ERP44	0	genome.wustl.edu	37	9	102744932	102744932	+	Frame_Shift_Del	DEL	A	A	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	102744932	102744932	A	-	DEL	ERP44	ENST00000262455	human	ensembl	74_37	-1	known	frame_shift_del	c.1183	p.Y395fs	1.000	NULL	pfam_Thioredoxin_domain,pfam_Calsequestrin,superfamily_Thioredoxin-like_fold	-	no_errors	ERP44	HGNC	ENSG00000023318	tier1			26	0	0.00	20	14	41.18
ESRRG	0	genome.wustl.edu	37	1	216896593	216896593	+	Nonsense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	216896593	216896593	C	A	SNP	ESRRG	ENST00000408911	human	ensembl	74_37	-1	known	nonsense	c.49	p.E17*	1.000	NULL	pfam_Nucl_hrmn_rcpt_lig-bd_core,pfam_Znf_hrmn_rcpt,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt,prints_Znf_hrmn_rcpt,prints_Retinoic_acid_rcpt	-	no_errors	ESRRG	HGNC	ENSG00000196482	tier1	-	-	34	0	0.00	25	13	34.21
FAM135A	0	genome.wustl.edu	37	6	71245981	71245981	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	71245981	71245981	G	T	SNP	FAM135A	ENST00000418814	human	ensembl	74_37	+1	known	missense	c.3984	p.L1328F	1.000	pfam_DUF676_lipase-like,pfam_PGAP1-like,pfam_LACT/PDAT_acylTrfase	pfam_DUF676_lipase-like,pfam_DUF3657,pfam_PGAP1-like,pfam_LACT/PDAT_acylTrfase	-	no_errors	FAM135A	HGNC	ENSG00000082269	tier1	-	-	47	0	0.00	72	4	5.26
FBXW4	0	genome.wustl.edu	37	10	103386257	103386257	+	RNA	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	103386257	103386257	T	-	DEL	FBXW4	ENST00000470093	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	FBXW4	HGNC	ENSG00000107829	tier1			24	0	0.00	12	2	14.29
FMO3	0	genome.wustl.edu	37	1	171086308	171086308	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	171086308	171086308	G	T	SNP	FMO3	ENST00000367755	human	ensembl	74_37	+1	known	missense	c.1325	p.G442V	1.000	pfam_Flavin_mOase-like,pirsf_DiMe-aniline_mOase,prints_Flavin_mOase_2	pfam_Flavin_mOase-like,pfam_Pyr_nucl-diS_OxRdtase_FAD/NAD,pirsf_DiMe-aniline_mOase,prints_Flavin_mOase,prints_Flavin_mOase_3,prints_Flavin_mOase_1,prints_Flavin_mOase_2	-	no_errors	FMO3	HGNC	ENSG00000007933				24	0	0.00	36	2	5.26
FSCN3	0	genome.wustl.edu	37	7	127238588	127238589	+	Frame_Shift_Ins	INS	-	-	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	127238588	127238589	-	G	INS	FSCN3	ENST00000265825	human	ensembl	74_37	+1	known	frame_shift_ins	c.1060_1061	p.R356fs	0.039:0.000	pfam_Fascin-domain,superfamily_Actin_cross-linking	pfam_Fascin-domain,superfamily_Actin_cross-linking	-	no_errors	FSCN3	HGNC	ENSG00000106328	tier1			23	0	0.00	28	2	6.67
FSIP2	0	genome.wustl.edu	37	2	186671724	186671724	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	186671724	186671724	G	A	SNP	FSIP2	ENST00000343098	human	ensembl	74_37	+1	known	missense	c.17958	p.M5986I	0.000	NULL	NULL	-	no_errors	FSIP2	HGNC	ENSG00000188738	tier1	-	-	21	0	0.00	31	6	16.22
GBP1P1	0	genome.wustl.edu	37	1	89885842	89885842	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	89885842	89885842	C	T	SNP	GBP1P1	ENST00000513638	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	GBP1P1	HGNC	ENSG00000225492	tier1	-	-	53	0	0.00	30	9	23.08
GCC2	0	genome.wustl.edu	37	2	109092295	109092295	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	109092295	109092295	G	A	SNP	GCC2	ENST00000309863	human	ensembl	74_37	+1	known	missense	c.3049	p.E1017K	1.000	NULL	pfam_GRIP,superfamily_GRIP,superfamily_tRNA-bd_arm,smart_GRIP,pfscan_GRIP	-	no_errors	GCC2	HGNC	ENSG00000135968	tier1	-	-	31	0	0.00	31	5	13.89
GLI3	0	genome.wustl.edu	37	7	42018223	42018223	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	42018223	42018223	G	A	SNP	GLI3	ENST00000395925	human	ensembl	74_37	-1	known	missense	c.1622	p.T541M	1.000	pfscan_Znf_C2H2	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLI3	HGNC	ENSG00000106571	tier1	-	-	47	0	0.00	44	4	8.33
GLOD4	0	genome.wustl.edu	37	17	679087	679087	+	Nonsense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	679087	679087	C	A	SNP	GLOD4	ENST00000301328	human	ensembl	74_37	-1	known	nonsense	c.379	p.E127*	0.997	NULL	NULL	-	no_errors	GLOD4	HGNC	ENSG00000167699				48	0	0.00	54	3	5.26
GOLGA8I	0	genome.wustl.edu	37	15	23257105	23257105	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	23257105	23257105	G	A	SNP	GOLGA8I	ENST00000450802	human	ensembl	74_37	+1	known	silent	c.96	p.A32	0.127	NULL	NULL	-	no_errors	GOLGA8I	HGNC	ENSG00000153666	tier1	rs200507088	-	39	0	0.00	7	3	30.00
GREB1	0	genome.wustl.edu	37	2	11742612	11742612	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	11742612	11742612	C	T	SNP	GREB1	ENST00000234142	human	ensembl	74_37	+1	known	silent	c.2610	p.L870	0.890	NULL	superfamily_P-loop_NTPase	-	no_errors	GREB1	HGNC	ENSG00000196208	tier1	-	-	86	0	0.00	94	20	17.39
GRIA4	0	genome.wustl.edu	37	11	105804513	105804513	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	105804513	105804513	C	G	SNP	GRIA4	ENST00000282499	human	ensembl	74_37	+1	known	missense	c.2112	p.F704L	1.000	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,smart_Iontro_glu_rcpt	pfam_ANF_lig-bd_rcpt,pfam_Iontro_glu_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIA4	HGNC	ENSG00000152578				38	0	0.00	22	4	15.38
GRIP1	0	genome.wustl.edu	37	12	66932939	66932939	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	66932939	66932939	G	A	SNP	GRIP1	ENST00000359742	human	ensembl	74_37	-1	known	missense	c.337	p.R113C	1.000	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	GRIP1	HGNC	ENSG00000155974	tier1	-	-	53	0	0.00	96	7	6.80
HAUS6	0	genome.wustl.edu	37	9	19096745	19096745	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	19096745	19096745	G	T	SNP	HAUS6	ENST00000380502	human	ensembl	74_37	-1	known	missense	c.151	p.R51S	1.000	NULL	NULL	-	no_errors	HAUS6	HGNC	ENSG00000147874				70	0	0.00	37	2	5.13
HBB	0	genome.wustl.edu	37	11	5248189	5248189	+	Silent	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	5248189	5248189	C	A	SNP	HBB	ENST00000335295	human	ensembl	74_37	-1	known	silent	c.63	p.V21	0.004	pfam_Globin,superfamily_Globin-like,pfscan_Globin	pfam_Globin,superfamily_Globin-like,pfscan_Globin,prints_Haemoglobin_b	-	no_errors	HBB	HGNC	ENSG00000244734	tier1	-	-	46	0	0.00	38	11	22.45
HDGF	0	genome.wustl.edu	37	1	156714052	156714052	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	156714052	156714052	C	T	SNP	HDGF	ENST00000368206	human	ensembl	74_37	-1	known	missense	c.440	p.G147D	1.000	NULL	pfam_PWWP_dom	-	no_errors	HDGF	HGNC	ENSG00000143321	tier1	-	-	48	0	0.00	44	4	8.33
HELLS	0	genome.wustl.edu	37	10	96331163	96331163	+	Frame_Shift_Del	DEL	A	A	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	96331163	96331163	A	-	DEL	HELLS	ENST00000371332	human	ensembl	74_37	+1	known	frame_shift_del	c.454	p.N154fs	1.000	NULL	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	HELLS	HGNC	ENSG00000119969	tier1			55	0	0.00	36	3	7.69
HEMGN	0	genome.wustl.edu	37	9	100693387	100693387	+	Missense_Mutation	SNP	A	A	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	100693387	100693387	A	T	SNP	HEMGN	ENST00000259456	human	ensembl	74_37	-1	known	missense	c.290	p.V97E	0.000	NULL	NULL	-	no_errors	HEMGN	HGNC	ENSG00000136929				36	0	0.00	42	4	5.63
HIST1H3G	0	genome.wustl.edu	37	6	26271561	26271561	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	26271561	26271561	G	A	SNP	HIST1H3G	ENST00000305910	human	ensembl	74_37	-1	known	missense	c.52	p.R18C	0.998	superfamily_Histone-fold,prints_Histone_H3	pfam_Histone_core_D,superfamily_Histone-fold,smart_Histone_H3,prints_Histone_H3	-	no_errors	HIST1H3G	HGNC	ENSG00000256018	tier1	-	-	59	0	0.00	46	15	24.59
HK2	0	genome.wustl.edu	37	2	75115128	75115128	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	75115128	75115128	C	T	SNP	HK2	ENST00000290573	human	ensembl	74_37	+1	known	missense	c.2318	p.S773L	1.000	pfam_Hexokinase_C	pfam_Hexokinase_C,pfam_Hexokinase_N,prints_Hexokinase	-	no_errors	HK2	HGNC	ENSG00000159399	tier1	-	-	34	0	0.00	19	15	44.12
HMGN1	0	genome.wustl.edu	37	21	40720242	40720242	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	21	40720242	40720242	C	T	SNP	HMGN1	ENST00000380749	human	ensembl	74_37	-1	known	silent	c.102	p.A34	0.759	pfam_HMGN_fam,smart_HMGN_fam,prints_HMGN_fam	pfam_HMGN_fam,smart_HMGN_fam,prints_HMGN_fam	-	no_errors	HMGN1	HGNC	ENSG00000205581	tier1	-	-	31	0	0.00	9	13	59.09
HSP90AA1	0	genome.wustl.edu	37	14	102552699	102552699	+	Nonsense_Mutation	SNP	T	T	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	102552699	102552699	T	A	SNP	HSP90AA1	ENST00000557234	human	ensembl	74_37	-1	known	nonsense	c.172	p.R58*	1.000	NULL	NULL	-	no_errors	HSP90AA1	HGNC	ENSG00000080824	tier1	-	-	22	0	0.00	19	13	40.62
HTT	0	genome.wustl.edu	37	4	3134324	3134324	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	3134324	3134324	G	A	SNP	HTT	ENST00000355072	human	ensembl	74_37	+1	known	missense	c.2272	p.D758N	1.000	superfamily_ARM-type_fold	pfam_Huntingtin_middle-repeat,pfam_HEAT,superfamily_ARM-type_fold,prints_Huntingtin	-	no_errors	HTT	HGNC	ENSG00000197386	tier1	-	-	37	0	0.00	19	5	20.83
IFT122	0	genome.wustl.edu	37	3	129195640	129195641	+	Frame_Shift_Ins	INS	-	-	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	129195640	129195641	-	A	INS	IFT122	ENST00000296266	human	ensembl	74_37	+1	known	frame_shift_ins	c.1296_1297	p.V433fs	1.000:1.000	NULL	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	IFT122	HGNC	ENSG00000163913	tier1			21	0	0.00	24	2	7.69
IGSF8	0	genome.wustl.edu	37	1	160062078	160062078	+	Missense_Mutation	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	160062078	160062078	T	C	SNP	IGSF8	ENST00000314485	human	ensembl	74_37	-1	known	missense	c.1720	p.M574V	1.000	NULL	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	IGSF8	HGNC	ENSG00000162729	tier1	-	-	26	0	0.00	19	14	42.42
INF2	0	genome.wustl.edu	37	14	105185166	105185166	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	105185166	105185166	C	T	SNP	INF2	ENST00000481338	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	INF2	HGNC	ENSG00000203485	tier1	-	-	75	0	0.00	90	5	5.26
INHBA	0	genome.wustl.edu	37	7	41730069	41730069	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	41730069	41730069	C	T	SNP	INHBA	ENST00000242208	human	ensembl	74_37	-1	known	missense	c.460	p.E154K	0.955	pfam_TGF-b_N	pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C,prints_Inhibin_betaA,prints_Inhibin_asu	-	no_errors	INHBA	HGNC	ENSG00000122641	tier1	-	-	20	0	0.00	14	9	39.13
ITGA8	0	genome.wustl.edu	37	10	15655758	15655758	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	15655758	15655758	G	T	SNP	ITGA8	ENST00000378076	human	ensembl	74_37	-1	known	missense	c.1454	p.P485Q	0.995	pfam_Integrin_alpha-2,smart_Int_alpha_beta-p,prints_Integrin_alpha	pfam_Integrin_alpha-2,pfam_FG-GAP,pfam_Integrin_alpha_C_CS,smart_Int_alpha_beta-p,prints_Integrin_alpha	-	no_errors	ITGA8	HGNC	ENSG00000077943				27	0	0.00	38	2	5.00
JAM3	0	genome.wustl.edu	37	11	134014150	134014150	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	134014150	134014150	C	T	SNP	JAM3	ENST00000529443	human	ensembl	74_37	+1	known	missense	c.406	p.R136C	0.995	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,pfam_CD80_C2-set,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	JAM3	HGNC	ENSG00000166086	tier1	-	-	46	0	0.00	27	12	30.77
KIAA0430	0	genome.wustl.edu	37	16	15719495	15719495	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	15719495	15719495	G	T	SNP	KIAA0430	ENST00000396368	human	ensembl	74_37	-1	known	missense	c.1687	p.R563S	1.000	pfam_Limkain_b1_cons_dom,smart_RRM_dom	pfam_Limkain_b1_cons_dom,pfam_NYN_limkain-b1,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	KIAA0430	HGNC	ENSG00000166783				57	0	0.00	71	4	5.26
KIAA1407	0	genome.wustl.edu	37	3	113697807	113697807	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	113697807	113697807	C	T	SNP	KIAA1407	ENST00000295878	human	ensembl	74_37	-1	known	silent	c.2358	p.T786	0.508	NULL	NULL	-	no_errors	KIAA1407	HGNC	ENSG00000163617				66	0	0.00	40	3	6.98
KIAA1468	0	genome.wustl.edu	37	18	59947599	59947599	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	59947599	59947599	C	A	SNP	KIAA1468	ENST00000398130	human	ensembl	74_37	+1	known	missense	c.2974	p.L992I	1.000	superfamily_ARM-type_fold	superfamily_ARM-type_fold,smart_LisH_dimerisation,pfscan_HEAT_type_2,pfscan_LisH_dimerisation	-	no_errors	KIAA1468	HGNC	ENSG00000134444	tier1	-	-	55	0	0.00	59	4	6.35
KIF11	0	genome.wustl.edu	37	10	94373192	94373192	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	94373192	94373192	G	T	SNP	KIF11	ENST00000260731	human	ensembl	74_37	+1	known	missense	c.848	p.R283L	1.000	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom	pfam_Kinesin_motor_dom,superfamily_P-loop_NTPase,smart_Kinesin_motor_dom,pfscan_Kinesin_motor_dom,prints_Kinesin_motor_dom	-	no_errors	KIF11	HGNC	ENSG00000138160	tier1	-	-	68	0	0.00	72	5	6.49
KIR2DL1	0	genome.wustl.edu	37	19	55286739	55286739	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	55286739	55286739	G	A	SNP	KIR2DL1	ENST00000336077	human	ensembl	74_37	+1	known	missense	c.493	p.E165K	0.002	pfam_Immunoglobulin,smart_Ig_sub	pfam_Immunoglobulin,smart_Ig_sub	-	no_errors	KIR2DL1	HGNC	ENSG00000125498	tier1	-	-	106	0	0.00	128	31	19.50
KLHDC4	0	genome.wustl.edu	37	16	87790005	87790005	+	Frame_Shift_Del	DEL	T	T	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	87790005	87790005	T	-	DEL	KLHDC4	ENST00000270583	human	ensembl	74_37	-1	known	frame_shift_del	c.270	p.T91fs	1.000	NULL	pfam_Kelch_2,pfam_Kelch_1	-	no_errors	KLHDC4	HGNC	ENSG00000104731	tier1			18	0	0.00	25	2	7.41
LEPR	0	genome.wustl.edu	37	1	66067198	66067198	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	66067198	66067198	C	T	SNP	LEPR	ENST00000349533	human	ensembl	74_37	+1	known	missense	c.1118	p.A373V	1.000	pfam_IgC2-like_lig-bd,pfscan_Ig-like_dom	pfam_IgC2-like_lig-bd,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	LEPR	HGNC	ENSG00000116678	tier1	-	-	55	0	0.00	14	28	66.67
LEPRE1	0	genome.wustl.edu	37	1	43218270	43218270	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	43218270	43218270	G	A	SNP	LEPRE1	ENST00000236040	human	ensembl	74_37	-1	known	missense	c.1411	p.R471W	1.000	smart_Pro_4_hyd_alph	pfam_Oxoglu/Fe-dep_dioxygenase,smart_Pro_4_hyd_alph	-	no_errors	LEPRE1	HGNC	ENSG00000117385	tier1	rs147230023	-	27	0	0.00	23	3	11.54
LNPEP	0	genome.wustl.edu	37	5	96341827	96341827	+	Silent	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	96341827	96341827	G	T	SNP	LNPEP	ENST00000231368	human	ensembl	74_37	+1	known	silent	c.1836	p.L612	0.998	NULL	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	LNPEP	HGNC	ENSG00000113441	tier1	-	-	51	0	0.00	43	4	8.51
LOC100134259	0	genome.wustl.edu	37	2	47083029	47083032	+	RNA	DEL	TATG	TATG	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	TATG	TATG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	47083029	47083032	TATG	-	DEL	LOC100134259	ENST00000495449	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004:0.001:0.001:0.000	-	-	-	no_errors	AC016722.2	Clone_based_vega_gene	ENSG00000239332	tier1			11	0	0.00	16	9	36.00
LOC101927746	0	genome.wustl.edu	37	7	100953991	100953991	+	RNA	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	100953991	100953991	C	A	SNP	LOC101927746	ENST00000419422	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.035	-	-	-	no_errors	RP11-132A1.4	Clone_based_vega_gene	ENSG00000232445	tier1	-	-	44	0	0.00	39	4	9.30
LOC388906	0	genome.wustl.edu	37	22	42670129	42670129	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	22	42670129	42670129	C	T	SNP	LOC388906	ENST00000332965	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	Z83851.3	Clone_based_vega_gene	ENSG00000182057	tier1	-	-	24	0	0.00	33	6	15.00
LRP10	0	genome.wustl.edu	37	14	23345472	23345472	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	23345472	23345472	C	A	SNP	LRP10	ENST00000359591	human	ensembl	74_37	+1	known	missense	c.1315	p.R439S	1.000	superfamily_LDrepeatLR_classA_rpt	pfam_LDrepeatLR_classA_rpt,pfam_CUB_dom,superfamily_CUB_dom,superfamily_LDrepeatLR_classA_rpt,smart_CUB_dom,smart_LDrepeatLR_classA_rpt,pfscan_CUB_dom,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP10	HGNC	ENSG00000197324	tier1	-	-	11	0	0.00	19	4	17.39
LRP2	0	genome.wustl.edu	37	2	170096091	170096091	+	Missense_Mutation	SNP	A	A	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	170096091	170096091	A	T	SNP	LRP2	ENST00000263816	human	ensembl	74_37	-1	known	missense	c.4240	p.S1414T	1.000	superfamily_Growth_fac_rcpt_N_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,superfamily_TIL_dom,smart_LDrepeatLR_classA_rpt,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP2	HGNC	ENSG00000081479	tier1	-	-	40	0	0.00	19	40	67.80
LRRC14B	0	genome.wustl.edu	37	5	191776	191776	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	191776	191776	C	T	SNP	LRRC14B	ENST00000328278	human	ensembl	74_37	+1	novel	silent	c.123	p.S41	1.000	NULL	NULL	-	no_errors	LRRC14B	HGNC	ENSG00000185028	tier1	-	-	40	0	0.00	56	4	6.67
LRRC37A3	0	genome.wustl.edu	37	17	62893154	62893154	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	62893154	62893154	C	T	SNP	LRRC37A3	ENST00000319651	human	ensembl	74_37	-1	known	silent	c.222	p.A74	0.000	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC37A3	HGNC	ENSG00000176809				48	0	0.00	77	6	7.23
LUC7L	0	genome.wustl.edu	37	16	240027	240027	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	240027	240027	C	T	SNP	LUC7L	ENST00000293872	human	ensembl	74_37	-1	known	missense	c.914	p.R305H	1.000	NULL	pfam_Luc7-rel	-	no_errors	LUC7L	HGNC	ENSG00000007392				62	0	0.00	53	4	7.02
LZTS2	0	genome.wustl.edu	37	10	102763412	102763412	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	102763412	102763412	C	A	SNP	LZTS2	ENST00000370220	human	ensembl	74_37	+1	known	missense	c.557	p.P186H	1.000	NULL	NULL	-	no_errors	LZTS2	HGNC	ENSG00000107816				33	0	0.00	33	2	5.71
MAP3K8	0	genome.wustl.edu	37	10	30749675	30749675	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	30749675	30749675	C	T	SNP	MAP3K8	ENST00000263056	human	ensembl	74_37	+1	known	silent	c.1314	p.L438	0.153	superfamily_Kinase-like_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP3K8	HGNC	ENSG00000107968				11	0	0.00	17	3	15.00
MAPK8	0	genome.wustl.edu	37	10	49628338	49628338	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	49628338	49628338	C	T	SNP	MAPK8	ENST00000360332	human	ensembl	74_37	+1	known	silent	c.591	p.I197	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_MAPK_JNK	-	no_errors	MAPK8	HGNC	ENSG00000107643				31	0	0.00	35	3	7.89
MATR3	0	genome.wustl.edu	37	5	138661312	138661312	+	Nonsense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	138661312	138661312	G	T	SNP	MATR3	ENST00000361059	human	ensembl	74_37	+1	known	nonsense	c.2332	p.E778*	1.000	NULL	smart_Znf_U1,smart_RRM_dom,pfscan_Znf_C2H2_matrin,pfscan_RRM_dom	-	no_errors	MATR3	HGNC	ENSG00000015479	tier1	-	-	23	0	0.00	14	3	17.65
MDN1	0	genome.wustl.edu	37	6	90398430	90398430	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	90398430	90398430	C	T	SNP	MDN1	ENST00000369393	human	ensembl	74_37	-1	known	silent	c.11121	p.V3707	0.326	pirsf_Midasin	pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-3,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_AAA+_ATPase,smart_VWF_A,pirsf_Midasin,pfscan_VWF_A	-	no_errors	MDN1	HGNC	ENSG00000112159	tier1	-	-	21	0	0.00	11	7	38.89
MDN1	0	genome.wustl.edu	37	6	90453354	90453354	+	Missense_Mutation	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	90453354	90453354	T	C	SNP	MDN1	ENST00000369393	human	ensembl	74_37	-1	known	missense	c.4258	p.M1420V	1.000	pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pirsf_Midasin	pfam_ATPase_dyneun-rel_AAA,pfam_ATPase_AAA-3,superfamily_P-loop_NTPase,superfamily_ARM-type_fold,smart_AAA+_ATPase,smart_VWF_A,pirsf_Midasin,pfscan_VWF_A	-	no_errors	MDN1	HGNC	ENSG00000112159				50	0	0.00	28	2	6.67
MED14	0	genome.wustl.edu	37	X	40513746	40513746	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	X	40513746	40513746	G	A	SNP	MED14	ENST00000324817	human	ensembl	74_37	-1	known	silent	c.4161	p.I1387	0.999	NULL	pfam_Mediator_Med14	-	no_errors	MED14	HGNC	ENSG00000180182	tier1	-	-	18	0	0.00	23	8	25.81
MED25	0	genome.wustl.edu	37	19	50334095	50334095	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	50334095	50334095	C	A	SNP	MED25	ENST00000312865	human	ensembl	74_37	+1	known	missense	c.1052	p.A351D	0.994	pfam_Mediator_Med25_SD1	pfam_Mediator_Med25_VWA,pfam_Mediator_Med25,pfam_Mediator_Med25_SD1,pfam_Mediator_Med25_NR-box	-	no_errors	MED25	HGNC	ENSG00000104973				12	0	0.00	15	4	21.05
MEPE	0	genome.wustl.edu	37	4	88767807	88767807	+	RNA	DEL	A	A	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	88767807	88767807	A	-	DEL	MEPE	ENST00000508016	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MEPE	HGNC	ENSG00000152595	tier1			28	0	0.00	20	2	9.09
MFAP1	0	genome.wustl.edu	37	15	44105232	44105233	+	Frame_Shift_Ins	INS	-	-	TTCC			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	44105232	44105233	-	TTCC	INS	MFAP1	ENST00000267812	human	ensembl	74_37	-1	known	frame_shift_ins	c.840_839	p.V281fs	1.000:1.000	pfam_MFAP1_C	pfam_MFAP1_C	-	no_errors	MFAP1	HGNC	ENSG00000140259	tier1			64	0	0.00	44	21	32.31
MGAM	0	genome.wustl.edu	37	7	141778736	141778736	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	7	141778736	141778736	C	T	SNP	MGAM	ENST00000475668	human	ensembl	74_37	+1	putative	silent	c.5775	p.A1925	0.000	superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	MGAM	HGNC	ENSG00000257335	tier1	-	-	88	0	0.00	54	34	38.64
MLLT4	0	genome.wustl.edu	37	6	168363200	168363200	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	168363200	168363200	C	A	SNP	MLLT4	ENST00000366806	human	ensembl	74_37	+1	known	missense	c.4900	p.R1634S	0.999	NULL	pfam_Ras-assoc,pfam_Dil_domain,pfam_PDZ,pfam_FHA_dom,superfamily_PDZ,superfamily_SMAD_FHA_domain,smart_Ras-assoc,smart_FHA_dom,smart_PDZ,pfscan_Dilute,pfscan_PDZ,pfscan_Ras-assoc	-	no_errors	MLLT4	HGNC	ENSG00000130396				41	0	0.00	36	3	7.69
MMP26	0	genome.wustl.edu	37	11	5009484	5009484	+	Missense_Mutation	SNP	T	T	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	5009484	5009484	T	G	SNP	MMP26	ENST00000300762	human	ensembl	74_37	+1	known	missense	c.43	p.C15G	0.198	NULL	pfam_Pept_M10_metallopeptidase,superfamily_Peptidoglycan-bd-like,smart_Peptidase_Metallo,prints_Pept_M10A	-	no_errors	MMP26	HGNC	ENSG00000167346	tier1	-	-	52	0	0.00	32	28	46.67
MMS19	0	genome.wustl.edu	37	10	99218606	99218606	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	99218606	99218606	C	T	SNP	MMS19	ENST00000370782	human	ensembl	74_37	-1	known	missense	c.3016	p.D1006N	1.000	superfamily_ARM-type_fold	pfam_Tscrpt_C,superfamily_ARM-type_fold	-	no_errors	MMS19	HGNC	ENSG00000155229	tier1	-	-	33	0	0.00	26	13	33.33
MON2	0	genome.wustl.edu	37	12	62902072	62902072	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	62902072	62902072	G	A	SNP	MON2	ENST00000393630	human	ensembl	74_37	+1	known	missense	c.796	p.E266K	1.000	superfamily_ARM-type_fold	pfam_DUF1981_Sec7_assoc,superfamily_ARM-type_fold	-	no_errors	MON2	HGNC	ENSG00000061987	tier1	-	-	45	0	0.00	77	16	17.20
MPG	0	genome.wustl.edu	37	16	135510	135510	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	135510	135510	G	A	SNP	MPG	ENST00000219431	human	ensembl	74_37	+1	known	missense	c.631	p.D211N	1.000	pfam_PurDNA_glycsylse,superfamily_Formyl_transferase_C-like,tigrfam_PurDNA_glycsylse	pfam_PurDNA_glycsylse,superfamily_Formyl_transferase_C-like,tigrfam_PurDNA_glycsylse	-	no_errors	MPG	HGNC	ENSG00000103152	tier1	-	-	56	0	0.00	55	13	19.12
MRPL19	0	genome.wustl.edu	37	2	75881943	75881943	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	75881943	75881943	G	A	SNP	MRPL19	ENST00000393909	human	ensembl	74_37	+1	known	missense	c.557	p.S186N	0.996	pfam_Ribosomal_L19,superfamily_Translation_prot_SH3-like	pfam_Ribosomal_L19,superfamily_Translation_prot_SH3-like,prints_Ribosomal_L19	-	no_errors	MRPL19	HGNC	ENSG00000115364	tier1	-	-	42	0	0.00	40	4	9.09
MRPL4	0	genome.wustl.edu	37	19	10370426	10370426	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	10370426	10370426	C	T	SNP	MRPL4	ENST00000253099	human	ensembl	74_37	+1	known	silent	c.873	p.S291	0.311	NULL	pfam_Ribosomal_L4/L1e,superfamily_Ribosomal_L4_dom,tigrfam_Ribosomal_L4/L1e_bac-type	-	no_errors	MRPL4	HGNC	ENSG00000105364	tier1	rs147343809	-	43	0	0.00	31	17	34.69
MRPL50	0	genome.wustl.edu	37	9	104160850	104160850	+	Missense_Mutation	SNP	T	T	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	104160850	104160850	T	A	SNP	MRPL50	ENST00000374865	human	ensembl	74_37	-1	known	missense	c.25	p.I9F	0.000	NULL	pfam_Ribosomal_L50_mt	-	no_errors	MRPL50	HGNC	ENSG00000136897	tier1	-	-	37	0	0.00	31	13	29.55
MVP	0	genome.wustl.edu	37	16	29859260	29859260	+	Nonsense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	29859260	29859260	C	T	SNP	MVP	ENST00000357402	human	ensembl	74_37	+1	known	nonsense	c.2632	p.Q878*	0.000	NULL	pfam_Vault_N,pfam_MVP_shoulder	-	no_errors	MVP	HGNC	ENSG00000013364	tier1	-	-	48	0	0.00	50	4	7.41
MYB	0	genome.wustl.edu	37	6	135515008	135515008	+	Missense_Mutation	SNP	A	A	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	135515008	135515008	A	C	SNP	MYB	ENST00000341911	human	ensembl	74_37	+1	known	missense	c.795	p.L265F	1.000	NULL	pfam_C-myb_C,pfam_SANT/Myb,pfam_Tscrpt_reg_Wos2-domain,superfamily_Homeodomain-like,smart_SANT/Myb,pfscan_Myb-like_dom	-	no_errors	MYB	HGNC	ENSG00000118513	tier1	-	-	67	0	0.00	40	16	28.57
MYO1D	0	genome.wustl.edu	37	17	30821801	30821801	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	30821801	30821801	G	A	SNP	MYO1D	ENST00000318217	human	ensembl	74_37	-1	known	silent	c.2997	p.F999	1.000	pfam_Myosin_tail_2	pfam_Myosin_head_motor_dom,pfam_Myosin_tail_2,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO1D	HGNC	ENSG00000176658				33	0	0.00	55	5	8.33
MYO5C	0	genome.wustl.edu	37	15	52513403	52513403	+	Missense_Mutation	SNP	T	T	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	52513403	52513403	T	G	SNP	MYO5C	ENST00000261839	human	ensembl	74_37	-1	known	missense	c.3677	p.Q1226P	1.000	NULL	pfam_Myosin_head_motor_dom,pfam_Dil_domain,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,pfscan_Dilute,pfscan_IQ_motif_EF-hand-BS,prints_Myosin_head_motor_dom	-	no_errors	MYO5C	HGNC	ENSG00000128833	tier1	-	-	59	0	0.00	57	20	25.97
NBPF4	0	genome.wustl.edu	37	1	108769358	108769358	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	108769358	108769358	C	T	SNP	NBPF4	ENST00000415641	human	ensembl	74_37	-1	known	silent	c.1818	p.P606	0.000	NULL	pfam_NBPF_dom	-	no_errors	NBPF4	HGNC	ENSG00000196427	tier1	-	-	17	0	0.00	4	2	33.33
NOTCH4	0	genome.wustl.edu	37	6	32187428	32187428	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	32187428	32187428	C	A	SNP	NOTCH4	ENST00000375023	human	ensembl	74_37	-1	known	missense	c.1451	p.C484F	1.000	pirsf_Notch,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pirsf_Notch,pfam_EG-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd_dom,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_4,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301				69	0	0.00	48	3	5.88
NPHS1	0	genome.wustl.edu	37	19	36339270	36339270	+	Silent	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	36339270	36339270	G	T	SNP	NPHS1	ENST00000378910	human	ensembl	74_37	-1	known	silent	c.1200	p.S400	0.972	pfam_CD80_C2-set,smart_Ig_sub,pfscan_Ig-like_dom	pfam_CD80_C2-set,pfam_Ig_I-set,pfam_Ig_V-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	NPHS1	HGNC	ENSG00000161270				25	0	0.00	38	2	5.00
NUF2	0	genome.wustl.edu	37	1	163310159	163310159	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	163310159	163310159	G	T	SNP	NUF2	ENST00000497990	human	ensembl	74_37	+1	known	missense	c.608	p.C203F	0.246	NULL	pfam_Kinetochore_Nuf2	-	no_errors	NUF2	HGNC	ENSG00000143228	tier1	-	-	53	0	0.00	60	4	6.25
NUP107	0	genome.wustl.edu	37	12	69109443	69109443	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	69109443	69109443	G	A	SNP	NUP107	ENST00000229179	human	ensembl	74_37	+1	known	missense	c.1006	p.D336N	1.000	pfam_Nup84_Nup100	pfam_Nup84_Nup100	-	no_errors	NUP107	HGNC	ENSG00000111581	tier1	-	-	59	0	0.00	195	103	34.56
OR4C16	0	genome.wustl.edu	37	11	55339864	55339864	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	55339864	55339864	G	C	SNP	OR4C16	ENST00000314634	human	ensembl	74_37	+1	known	missense	c.261	p.K87N	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4C16	HGNC	ENSG00000181935	tier1	-	-	53	0	0.00	48	16	25.00
OR4K2	0	genome.wustl.edu	37	14	20345270	20345270	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	20345270	20345270	C	T	SNP	OR4K2	ENST00000298642	human	ensembl	74_37	+1	known	silent	c.844	p.L282	0.003	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR4K2	HGNC	ENSG00000165762				37	0	0.00	33	3	8.33
OSBPL1A	0	genome.wustl.edu	37	18	21897350	21897350	+	Frame_Shift_Del	DEL	A	A	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	21897350	21897350	A	-	DEL	OSBPL1A	ENST00000319481	human	ensembl	74_37	-1	known	frame_shift_del	c.747	p.F249fs	1.000	smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_Oxysterol-bd,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Pleckstrin_homology,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Pleckstrin_homology,prints_Ankyrin_rpt	-	no_errors	OSBPL1A	HGNC	ENSG00000141447	tier1			31	0	0.00	31	2	6.06
OSMR	0	genome.wustl.edu	37	5	38885478	38885478	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	38885478	38885478	C	A	SNP	OSMR	ENST00000274276	human	ensembl	74_37	+1	known	missense	c.731	p.S244Y	1.000	superfamily_Fibronectin_type3	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	OSMR	HGNC	ENSG00000145623				37	0	0.00	32	2	5.88
OVGP1	0	genome.wustl.edu	37	1	111957458	111957458	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	111957458	111957458	C	T	SNP	OVGP1	ENST00000369732	human	ensembl	74_37	-1	known	silent	c.1665	p.E555	0.015	NULL	pfam_Glyco_hydro18cat,superfamily_Glycoside_hydrolase_SF,smart_Chitinase_II	-	no_errors	OVGP1	HGNC	ENSG00000085465	tier1	-	-	39	0	0.00	29	7	19.44
PCDH9	0	genome.wustl.edu	37	13	66878818	66878818	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	13	66878818	66878818	G	T	SNP	PCDH9	ENST00000377865	human	ensembl	74_37	-1	known	missense	c.3683	p.A1228D	0.990	NULL	pfam_Cadherin,pfam_Protocadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH9	HGNC	ENSG00000184226	tier1	-	-	29	0	0.00	25	6	19.35
PCDHA3	0	genome.wustl.edu	37	5	140181370	140181371	+	Frame_Shift_Ins	INS	-	-	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	140181370	140181371	-	A	INS	PCDHA3	ENST00000522353	human	ensembl	74_37	+1	known	frame_shift_ins	c.588_589	p.N198fs	0.860:0.987	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA3	HGNC	ENSG00000255408	tier1			20	0	0.00	22	3	12.00
PCDHA5	0	genome.wustl.edu	37	5	140203783	140203783	+	Missense_Mutation	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	140203783	140203783	T	C	SNP	PCDHA5	ENST00000378126	human	ensembl	74_37	+1	known	missense	c.2423	p.L808P	0.000	NULL	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA5	HGNC	ENSG00000204965				10	0	0.00	15	2	11.76
PDE3A	0	genome.wustl.edu	37	12	20523043	20523043	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	20523043	20523043	G	A	SNP	PDE3A	ENST00000359062	human	ensembl	74_37	+1	known	silent	c.825	p.L275	0.011	NULL	pfam_PDEase_catalytic_dom,smart_HD/PDEase_dom	-	no_errors	PDE3A	HGNC	ENSG00000172572				12	0	0.00	20	4	16.67
PENK	0	genome.wustl.edu	37	8	57358447	57358447	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	57358447	57358447	C	T	SNP	PENK	ENST00000314922	human	ensembl	74_37	-1	known	silent	c.66	p.V22	0.000	pfam_Opioid_neupept,prints_Proenkphlin_A	pfam_Opioid_neupept,prints_Proenkphlin_A,prints_Opioid_neupept	-	no_errors	PENK	HGNC	ENSG00000181195	tier1	rs149051933	-	29	0	0.00	12	11	47.83
PES1	0	genome.wustl.edu	37	22	30973103	30973103	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	22	30973103	30973103	G	T	SNP	PES1	ENST00000354694	human	ensembl	74_37	-1	known	missense	c.1697	p.A566E	0.998	NULL	pfam_Pescadillo,pfam_BRCT_dom,superfamily_BRCT_dom,smart_BRCT_dom,pfscan_BRCT_dom	-	no_errors	PES1	HGNC	ENSG00000100029	tier1	-	-	45	0	0.00	75	4	5.06
PGR	0	genome.wustl.edu	37	11	100922294	100922294	+	Nonsense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	100922294	100922294	G	A	SNP	PGR	ENST00000325455	human	ensembl	74_37	-1	known	nonsense	c.2218	p.R740*	1.000	superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Nucl_hrmn_rcpt_lig-bd_core,prints_Str_hrmn_rcpt	pfam_Progest_rcpt,pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Progest_rcpt,prints_Znf_hrmn_rcpt,prints_Str_hrmn_rcpt	-	no_errors	PGR	HGNC	ENSG00000082175	tier1	-	-	13	0	0.00	4	9	69.23
PHF13	0	genome.wustl.edu	37	1	6681626	6681626	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	6681626	6681626	C	T	SNP	PHF13	ENST00000377648	human	ensembl	74_37	+1	known	missense	c.832	p.R278W	1.000	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD	-	no_errors	PHF13	HGNC	ENSG00000116273				51	0	0.00	30	2	6.25
PIGQ	0	genome.wustl.edu	37	16	633575	633575	+	Missense_Mutation	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	633575	633575	T	C	SNP	PIGQ	ENST00000026218	human	ensembl	74_37	+1	known	missense	c.2224	p.S742P	0.000	NULL	pfam_GlcNAc_Gpi1	-	no_errors	PIGQ	HGNC	ENSG00000007541	tier1	-	-	34	0	0.00	46	4	8.00
PLAG1	0	genome.wustl.edu	37	8	57079116	57079116	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	57079116	57079116	C	G	SNP	PLAG1	ENST00000316981	human	ensembl	74_37	-1	known	missense	c.1189	p.D397H	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	PLAG1	HGNC	ENSG00000181690	tier1	-	-	34	0	0.00	20	23	53.49
PLCE1	0	genome.wustl.edu	37	10	96005983	96005983	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	96005983	96005983	C	A	SNP	PLCE1	ENST00000260766	human	ensembl	74_37	+1	known	missense	c.2701	p.P901T	0.910	NULL	pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLipase_C_Pinositol-sp_Y,pfam_Ras-assoc,pfam_RasGRF_CDC25,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_Ras_GEF_dom,superfamily_C2_dom,smart_RasGRF_CDC25,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,smart_Ras-assoc,pfscan_C2_dom,pfscan_Ras-assoc,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y,pfscan_RasGRF_CDC25,prints_Pinositol_PLipase_C	-	no_errors	PLCE1	HGNC	ENSG00000138193				25	0	0.00	46	4	8.00
PLD5	0	genome.wustl.edu	37	1	242687455	242687455	+	Missense_Mutation	SNP	T	T	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	242687455	242687455	T	G	SNP	PLD5	ENST00000536534	human	ensembl	74_37	-1	known	missense	c.124	p.S42R	1.000	NULL	smart_PLipase_D/transphosphatidylase	-	no_errors	PLD5	HGNC	ENSG00000180287	tier1	-	-	83	0	0.00	61	40	39.22
PLEKHH2	0	genome.wustl.edu	37	2	43971084	43971084	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	43971084	43971084	C	T	SNP	PLEKHH2	ENST00000282406	human	ensembl	74_37	+1	known	missense	c.3511	p.P1171S	1.000	smart_Band_41_domain,pfscan_FERM_domain	pfam_Pleckstrin_homology,pfam_MyTH4_dom,pfam_FERM_central,superfamily_FERM_central,smart_Pleckstrin_homology,smart_MyTH4_dom,smart_Band_41_domain,pfscan_FERM_domain,pfscan_MyTH4_dom,pfscan_Pleckstrin_homology	-	no_errors	PLEKHH2	HGNC	ENSG00000152527				13	0	0.00	17	4	19.05
PLXDC2	0	genome.wustl.edu	37	10	20568869	20568869	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	20568869	20568869	G	A	SNP	PLXDC2	ENST00000377238	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	PLXDC2	HGNC	ENSG00000120594	tier1	-	-	18	0	0.00	11	8	42.11
PPARGC1A	0	genome.wustl.edu	37	4	23815983	23815983	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	23815983	23815983	G	A	SNP	PPARGC1A	ENST00000264867	human	ensembl	74_37	-1	known	missense	c.1123	p.R375W	1.000	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	PPARGC1A	HGNC	ENSG00000109819				16	0	0.00	15	2	11.76
PPFIA2	0	genome.wustl.edu	37	12	81760937	81760937	+	Missense_Mutation	SNP	G	G	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	81760937	81760937	G	C	SNP	PPFIA2	ENST00000549396	human	ensembl	74_37	-1	known	missense	c.1495	p.Q499E	1.000	NULL	pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_SAM,pfscan_SAM	-	no_errors	PPFIA2	HGNC	ENSG00000139220	tier1	-	-	99	0	0.00	27	57	67.06
PPIP5K2	0	genome.wustl.edu	37	5	102465376	102465376	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	102465376	102465376	C	T	SNP	PPIP5K2	ENST00000358359	human	ensembl	74_37	+1	known	missense	c.83	p.A28V	1.000	NULL	pfam_His_Pase_superF_clade-2	-	no_errors	PPIP5K2	HGNC	ENSG00000145725	tier1	-	-	24	0	0.00	8	3	27.27
PPM1K	0	genome.wustl.edu	37	4	89198310	89198310	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	89198310	89198310	G	T	SNP	PPM1K	ENST00000608933	human	ensembl	74_37	-1	known	missense	c.526	p.R176S	1.000	pfam_PP2C-like_dom,superfamily_PP2C-like_dom,smart_PP2C-like_dom	pfam_PP2C-like_dom,superfamily_PP2C-like_dom,smart_PP2C-like_dom	-	no_errors	PPM1K	HGNC	ENSG00000163644				55	0	0.00	30	3	9.09
PRC1	0	genome.wustl.edu	37	15	91525181	91525181	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	91525181	91525181	C	G	SNP	PRC1	ENST00000394249	human	ensembl	74_37	-1	known	missense	c.298	p.E100Q	1.000	pfam_MAP65_Ase1_PRC1	pfam_MAP65_Ase1_PRC1	-	no_errors	PRC1	HGNC	ENSG00000198901	tier1	-	-	40	0	0.00	49	11	18.33
PRR12	0	genome.wustl.edu	37	19	50102744	50102744	+	Silent	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	50102744	50102744	C	G	SNP	PRR12	ENST00000418929	human	ensembl	74_37	+1	novel	silent	c.3894	p.L1298	0.858	NULL	NULL	-	no_errors	PRR12	HGNC	ENSG00000126464	tier1	-	-	49	0	0.00	57	21	26.92
PSD3	0	genome.wustl.edu	37	8	18490287	18490287	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	18490287	18490287	G	A	SNP	PSD3	ENST00000440756	human	ensembl	74_37	-1	known	missense	c.2252	p.S751L	0.980	NULL	pfam_Sec7_dom,pfam_Pleckstrin_homology,superfamily_Sec7_dom,smart_Sec7_dom,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_Sec7_dom	-	no_errors	PSD3	HGNC	ENSG00000156011	tier1	-	-	57	0	0.00	23	9	28.12
PSMG1	0	genome.wustl.edu	37	21	40551903	40551904	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	AG	AG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	21	40551903	40551904	AG	-	DEL	PSMG1	ENST00000331573	human	ensembl	74_37	-1	known	frame_shift_del	c.403_402	p.C135fs	0.986:0.079	pirsf_Proteasome_assmbl_chp_1	pirsf_Proteasome_assmbl_chp_1	-	no_errors	PSMG1	HGNC	ENSG00000183527	tier1			25	0	0.00	24	2	7.69
PTPRD	0	genome.wustl.edu	37	9	8484252	8484252	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	8484252	8484252	C	T	SNP	PTPRD	ENST00000356435	human	ensembl	74_37	-1	known	missense	c.3280	p.G1094R	1.000	superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRD	HGNC	ENSG00000153707	tier1	-	-	61	0	0.00	34	19	35.85
RALGAPA2	0	genome.wustl.edu	37	20	20563841	20563841	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	20563841	20563841	C	A	SNP	RALGAPA2	ENST00000202677	human	ensembl	74_37	-1	known	missense	c.2560	p.G854C	1.000	NULL	pfam_Rap_GAP_dom,superfamily_ARM-type_fold,pfscan_Rap_GAP_dom	-	no_errors	RALGAPA2	HGNC	ENSG00000188559	tier1	-	-	49	0	0.00	35	12	25.53
RAP1GAP	0	genome.wustl.edu	37	1	21934815	21934815	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	21934815	21934815	G	T	SNP	RAP1GAP	ENST00000290101	human	ensembl	74_37	-1	known	missense	c.1379	p.T460K	1.000	pfam_Rap_GAP_dom,pfscan_Rap_GAP_dom	pfam_Rap_GAP_dom,pfam_GoLoco_motif,smart_GoLoco_motif,pfscan_GoLoco_motif,pfscan_Rap_GAP_dom	-	no_errors	RAP1GAP	HGNC	ENSG00000076864				30	0	0.00	34	2	5.56
RBMY1A1	0	genome.wustl.edu	37	Y	23702662	23702662	+	Splice_Site	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	Y	23702662	23702662	G	A	SNP	RBMY1A1	ENST00000303902	human	ensembl	74_37	+1	known	splice_site	c.391+1	e3+1	0.474	-	-	-	no_errors	RBMY1A1	HGNC	ENSG00000234414	tier1	-	-	298	0	0.00	127	17	11.81
RSU1	0	genome.wustl.edu	37	10	16796955	16796955	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	16796955	16796955	G	A	SNP	RSU1	ENST00000345264	human	ensembl	74_37	-1	known	silent	c.315	p.F105	0.999	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	RSU1	HGNC	ENSG00000148484	tier1	-	-	69	0	0.00	58	12	16.90
RUFY3	0	genome.wustl.edu	37	4	71634361	71634361	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	71634361	71634361	G	A	SNP	RUFY3	ENST00000417478	human	ensembl	74_37	+1	known	missense	c.859	p.E287K	1.000	pfscan_Run	pfam_Run,superfamily_Prefoldin,smart_Run,pfscan_Run	-	no_errors	RUFY3	HGNC	ENSG00000018189	tier1	-	-	71	0	0.00	25	20	44.44
RYR2	0	genome.wustl.edu	37	1	237991692	237991692	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	237991692	237991692	G	T	SNP	RYR2	ENST00000360064	human	ensembl	74_37	+1	known	missense	c.14620	p.D4874Y	1.000	NULL	pfam_Ca-rel_channel,pfam_Ryanodine_rcpt,pfam_Ryanrecept_TM4-6,pfam_SPRY_rcpt,pfam_Ins145_P3_rcpt,pfam_MIR_motif,pfam_RIH_assoc-dom,pfam_Ion_trans_dom,superfamily_MIR_motif,superfamily_ConA-like_lec_gl_sf,smart_MIR_motif,smart_SPla/RYanodine_receptor_subgr,prints_Ryan_recept,pfscan_B30.2/SPRY,pfscan_EF_hand_dom,pfscan_MIR_motif	-	no_errors	RYR2	HGNC	ENSG00000198626	tier1	-	-	48	0	0.00	42	4	8.70
SCAP	0	genome.wustl.edu	37	3	47462508	47462508	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	47462508	47462508	G	A	SNP	SCAP	ENST00000320017	human	ensembl	74_37	-1	known	missense	c.472	p.L158F	1.000	NULL	NULL	-	no_errors	SCAP	HGNC	ENSG00000114650	tier1	-	-	17	0	0.00	11	5	31.25
SDF2	0	genome.wustl.edu	37	17	26988906	26988906	+	RNA	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	26988906	26988906	C	G	SNP	SDF2	ENST00000585428	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SDF2	HGNC	ENSG00000132581	tier1	-	-	26	0	0.00	13	8	38.10
SEC22B	0	genome.wustl.edu	37	1	145116193	145116193	+	RNA	DEL	G	G	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	145116193	145116193	G	-	DEL	SEC22B	ENST00000453618	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.031	-	-	-	no_errors	SEC22B	HGNC	ENSG00000223380	tier1			30	0	0.00	43	8	15.69
SEMA4B	0	genome.wustl.edu	37	15	90771613	90771613	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	90771613	90771613	G	A	SNP	SEMA4B	ENST00000332496	human	ensembl	74_37	+1	known	missense	c.2252	p.G751E	0.997	NULL	pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom	-	no_errors	SEMA4B	HGNC	ENSG00000185033	tier1	-	-	24	0	0.00	23	15	39.47
SERPINB13	0	genome.wustl.edu	37	18	61264278	61264278	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	61264278	61264278	C	G	SNP	SERPINB13	ENST00000344731	human	ensembl	74_37	+1	known	missense	c.857	p.P286R	1.000	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	-	no_errors	SERPINB13	HGNC	ENSG00000197641	tier1	-	-	50	0	0.00	30	22	42.31
SETD1B	0	genome.wustl.edu	37	12	122247572	122247572	+	Missense_Mutation	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	122247572	122247572	T	C	SNP	SETD1B	ENST00000267197	human	ensembl	74_37	+1	known	missense	c.721	p.S241P	0.942	NULL	pfam_COMPASS_Set1_N-SET,pfam_SET_dom,pfam_RRM_dom,smart_RRM_dom,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_RRM_dom	-	no_errors	SETD1B	HGNC	ENSG00000139718	tier1	-	-	36	0	0.00	27	4	12.90
SI	0	genome.wustl.edu	37	3	164786915	164786915	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	164786915	164786915	G	A	SNP	SI	ENST00000264382	human	ensembl	74_37	-1	known	silent	c.324	p.F108	0.226	pfam_P_trefoil,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	SI	HGNC	ENSG00000090402	tier1	-	-	52	0	0.00	82	11	11.83
SKIDA1	0	genome.wustl.edu	37	10	21805721	21805723	+	In_Frame_Del	DEL	TGG	TGG	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	TGG	TGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	21805721	21805723	TGG	-	DEL	SKIDA1	ENST00000449193	human	ensembl	74_37	-1	known	in_frame_del	c.1031_1029	p.H347in_frame_del	1.000:1.000:1.000	NULL	pfam_Transform_Ski,superfamily_DNA-bd_dom_put	-	no_errors	SKIDA1	HGNC	ENSG00000180592	tier1			59	0	0.00	57	7	10.94
SLAIN2	0	genome.wustl.edu	37	4	48384732	48384732	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	48384732	48384732	C	A	SNP	SLAIN2	ENST00000264313	human	ensembl	74_37	+1	known	missense	c.1010	p.P337H	1.000	NULL	NULL	-	no_errors	SLAIN2	HGNC	ENSG00000109171	tier1	-	-	35	0	0.00	12	3	20.00
SLC10A5	0	genome.wustl.edu	37	8	82606673	82606673	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	82606673	82606673	G	A	SNP	SLC10A5	ENST00000518568	human	ensembl	74_37	-1	known	missense	c.535	p.L179F	1.000	pfam_BilAc/Na_symport	pfam_BilAc/Na_symport	-	no_errors	SLC10A5	HGNC	ENSG00000253598	tier1	-	-	15	0	0.00	13	5	27.78
SLC23A2	0	genome.wustl.edu	37	20	4913292	4913292	+	RNA	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	4913292	4913292	C	T	SNP	SLC23A2	ENST00000468355	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	SLC23A2	HGNC	ENSG00000089057	tier1	-	-	9	0	0.00	8	5	38.46
SLC25A44	0	genome.wustl.edu	37	1	156180847	156180848	+	RNA	INS	-	-	TG			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	1	156180847	156180848	-	TG	INS	SLC25A44	ENST00000469537	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.081:0.000	-	-	-	no_errors	SLC25A44	HGNC	ENSG00000160785	tier1			17	0	0.00	20	2	9.09
SLC46A2	0	genome.wustl.edu	37	9	115651961	115651961	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	115651961	115651961	C	T	SNP	SLC46A2	ENST00000374228	human	ensembl	74_37	-1	known	missense	c.1001	p.S334N	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,prints_Tet-R_TetA/multi-R_MdtG	-	no_errors	SLC46A2	HGNC	ENSG00000119457				22	0	0.00	45	4	8.16
SLC4A11	0	genome.wustl.edu	37	20	3211194	3211194	+	Frame_Shift_Del	DEL	A	A	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	3211194	3211194	A	-	DEL	SLC4A11	ENST00000380059	human	ensembl	74_37	-1	known	frame_shift_del	c.1511	p.F504fs	1.000	pfam_HCO3_transpt_C	pfam_HCO3_transpt_C,pfam_PTS_EIIA_type-2_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk	-	no_errors	SLC4A11	HGNC	ENSG00000088836	tier1			17	0	0.00	20	2	9.09
SMOC1	0	genome.wustl.edu	37	14	70477552	70477552	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	70477552	70477552	C	T	SNP	SMOC1	ENST00000361956	human	ensembl	74_37	+1	known	missense	c.746	p.P249L	1.000	pfam_Thyroglobulin_1,superfamily_Thyroglobulin_1,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	pfam_Thyroglobulin_1,pfam_SPARC/Testican_Ca-bd-dom,pfam_Kazal_dom,superfamily_Thyroglobulin_1,smart_Kazal_dom,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1	-	no_errors	SMOC1	HGNC	ENSG00000198732				31	0	0.00	44	3	6.38
SNAI1	0	genome.wustl.edu	37	20	48600834	48600834	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	20	48600834	48600834	G	A	SNP	SNAI1	ENST00000244050	human	ensembl	74_37	+1	known	missense	c.556	p.G186R	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	SNAI1	HGNC	ENSG00000124216	tier1	-	-	34	0	0.00	23	5	17.86
SNORD115-1	0	genome.wustl.edu	37	15	25415878	25415878	+	RNA	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	25415878	25415878	G	A	SNP	SNORD115-1	ENST00000364961	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	SNORD115-1	HGNC	ENSG00000201831	tier1	-	-	57	0	0.00	41	9	18.00
SOS1	0	genome.wustl.edu	37	2	39249845	39249845	+	Missense_Mutation	SNP	T	T	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	39249845	39249845	T	A	SNP	SOS1	ENST00000402219	human	ensembl	74_37	-1	known	missense	c.1724	p.Y575F	1.000	superfamily_Ras_GEF_dom	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_DH-domain,pfam_Pleckstrin_homology,pfam_Histone_core_D,superfamily_Ras_GEF_dom,superfamily_Histone-fold,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_Pleckstrin_homology,pfscan_DH-domain,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	SOS1	HGNC	ENSG00000115904				39	0	0.00	49	3	5.77
SPICE1	0	genome.wustl.edu	37	3	113187975	113187975	+	Nonsense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	113187975	113187975	G	T	SNP	SPICE1	ENST00000295872	human	ensembl	74_37	-1	known	nonsense	c.722	p.S241*	0.023	NULL	NULL	-	no_errors	SPICE1	HGNC	ENSG00000163611	tier1	-	-	51	0	0.00	27	10	27.03
SPOPL	0	genome.wustl.edu	37	2	139326574	139326574	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	139326574	139326574	C	A	SNP	SPOPL	ENST00000280098	human	ensembl	74_37	+1	known	missense	c.1103	p.A368E	1.000	NULL	pfam_BTB_POZ,pfam_MATH,superfamily_TRAF-like,superfamily_BTB/POZ_fold,smart_MATH,smart_BTB/POZ-like,pfscan_BTB/POZ-like,pfscan_MATH	-	no_errors	SPOPL	HGNC	ENSG00000144228				42	0	0.00	34	2	5.56
SPTY2D1	0	genome.wustl.edu	37	11	18637589	18637589	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	18637589	18637589	G	T	SNP	SPTY2D1	ENST00000336349	human	ensembl	74_37	-1	known	missense	c.232	p.H78N	1.000	NULL	pfam_Chromatin_SPT2,smart_Chromatin_SPT2	-	no_errors	SPTY2D1	HGNC	ENSG00000179119				53	0	0.00	47	4	7.84
SRGAP1	0	genome.wustl.edu	37	12	64456779	64456779	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	64456779	64456779	G	A	SNP	SRGAP1	ENST00000355086	human	ensembl	74_37	+1	known	missense	c.884	p.R295K	1.000	NULL	pfam_RhoGAP_dom,pfam_FCH_dom,pfam_SH3_domain,pfam_SH3_2,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_Fuc/Ara_isomerase_C,smart_FCH_dom,smart_RhoGAP_dom,smart_SH3_domain,pfscan_FCH_dom,pfscan_SH3_domain,pfscan_RhoGAP_dom	-	no_errors	SRGAP1	HGNC	ENSG00000196935	tier1	-	-	58	0	0.00	65	13	16.67
TANC1	0	genome.wustl.edu	37	2	160087164	160087165	+	Frame_Shift_Ins	INS	-	-	GC			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	160087164	160087165	-	GC	INS	TANC1	ENST00000263635	human	ensembl	74_37	+1	known	frame_shift_ins	c.5227_5228	p.W1744fs	0.129:0.681	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,smart_Ankyrin_rpt,smart_TPR_repeat,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Ankyrin_rpt	-	no_errors	TANC1	HGNC	ENSG00000115183	tier1			25	0	0.00	27	4	12.90
TBCCD1	0	genome.wustl.edu	37	3	186281915	186281915	+	Silent	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	186281915	186281915	G	T	SNP	TBCCD1	ENST00000338733	human	ensembl	74_37	-1	known	silent	c.204	p.A68	0.528	NULL	pfam_Tubulin-bd_cofactor_C_dom,superfamily_Adenylate_cyclase-assoc_CAP_C,smart_CARP_motif	-	no_errors	TBCCD1	HGNC	ENSG00000113838				27	0	0.00	73	4	5.19
TENM2	0	genome.wustl.edu	37	5	167675195	167675195	+	Frame_Shift_Del	DEL	C	C	-			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	167675195	167675195	C	-	DEL	TENM2	ENST00000518659	human	ensembl	74_37	+1	known	frame_shift_del	c.7251	p.L2419fs	1.000	tigrfam_Rhs_assc_core	pfam_Ten_N,pfam_EGF_extracell,superfamily_CarboxyPept-like_regulatory,superfamily_Quino_amine_DH_bsu,superfamily_ConA-like_lec_gl_sf,superfamily_Cytokine_IL1-like,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core	-	no_errors	TENM2	HGNC	ENSG00000145934	tier1			28	0	0.00	27	3	10.00
TET2	0	genome.wustl.edu	37	4	106157695	106157695	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	4	106157695	106157695	C	A	SNP	TET2	ENST00000380013	human	ensembl	74_37	+1	known	missense	c.2596	p.Q866K	1.000	NULL	NULL	-	no_errors	TET2	HGNC	ENSG00000168769				22	0	0.00	12	2	14.29
TET3	0	genome.wustl.edu	37	2	74327953	74327953	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	74327953	74327953	C	T	SNP	TET3	ENST00000409262	human	ensembl	74_37	+1	known	silent	c.3633	p.P1211	0.780	NULL	NULL	-	no_errors	TET3	HGNC	ENSG00000187605				20	0	0.00	32	4	11.11
TFAP2B	0	genome.wustl.edu	37	6	50805745	50805745	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	50805745	50805745	G	T	SNP	TFAP2B	ENST00000263046	human	ensembl	74_37	+1	known	missense	c.906	p.L302F	1.000	pfam_TF_AP2_C,prints_TF_AP2_C	pfam_TF_AP2_C,prints_TF_AP2_beta,prints_TF_AP2_C	-	no_errors	TFAP2B	HGNC	ENSG00000008196	tier1	-	-	40	0	0.00	42	4	8.51
TMEM249	0	genome.wustl.edu	37	8	145578374	145578374	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	8	145578374	145578374	G	A	SNP	TMEM249	ENST00000398633	human	ensembl	74_37	-1	known	silent	c.54	p.F18	0.716	NULL	NULL	-	no_errors	TMEM249	HGNC	ENSG00000214597	tier1	-	-	36	0	0.00	24	14	36.84
TNKS1BP1	0	genome.wustl.edu	37	11	57077682	57077682	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	11	57077682	57077682	G	A	SNP	TNKS1BP1	ENST00000358252	human	ensembl	74_37	-1	known	missense	c.2503	p.R835W	0.189	NULL	NULL	-	no_errors	TNKS1BP1	HGNC	ENSG00000149115				22	0	0.00	24	3	11.11
TNKS2	0	genome.wustl.edu	37	10	93604699	93604699	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	10	93604699	93604699	G	T	SNP	TNKS2	ENST00000371627	human	ensembl	74_37	+1	known	missense	c.2083	p.A695S	1.000	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_Ankyrin_rpt,pfam_Poly(ADP-ribose)pol_cat_dom,pfam_SAM_2,pfam_SAM_type1,superfamily_Ankyrin_rpt-contain_dom,superfamily_SAM/pointed,smart_Ankyrin_rpt,smart_SAM,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_SAM,pfscan_Poly(ADP-ribose)pol_cat_dom,prints_Ankyrin_rpt	-	no_errors	TNKS2	HGNC	ENSG00000107854				47	0	0.00	64	4	5.88
TOX3	0	genome.wustl.edu	37	16	52484196	52484196	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	52484196	52484196	G	T	SNP	TOX3	ENST00000219746	human	ensembl	74_37	-1	known	missense	c.671	p.A224D	0.996	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	TOX3	HGNC	ENSG00000103460	tier1	-	-	17	0	0.00	15	4	21.05
TP53	0	genome.wustl.edu	37	17	7578553	7578553	+	Missense_Mutation	SNP	T	T	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	17	7578553	7578553	T	G	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.377	p.Y126S	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	31	0	0.00	6	7	53.85
TSHR	0	genome.wustl.edu	37	14	81609998	81609998	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	81609998	81609998	G	A	SNP	TSHR	ENST00000298171	human	ensembl	74_37	+1	known	silent	c.1596	p.K532	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_TSH_rcpt,prints_Gphrmn_rcpt_fam,prints_GPCR_Rhodpsn,prints_FSH_rcpt,prints_LSH_rcpt	-	no_errors	TSHR	HGNC	ENSG00000165409	tier1	-	-	30	0	0.00	27	12	30.77
TTN	0	genome.wustl.edu	37	2	179399177	179399177	+	Silent	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	179399177	179399177	C	G	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	silent	c.94461	p.V31487	1.000	pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	19	0	0.00	19	7	26.92
TTN	0	genome.wustl.edu	37	2	179459077	179459077	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	179459077	179459077	C	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.50440	p.E16814K	1.000	superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	44	0	0.00	59	12	16.90
TTN	0	genome.wustl.edu	37	2	179393123	179393123	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	179393123	179393123	C	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	missense	c.99551	p.R33184H	1.000	pfam_Ig_I-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657				15	0	0.00	36	2	5.26
TXNRD1	0	genome.wustl.edu	37	12	104682792	104682792	+	Missense_Mutation	SNP	A	A	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	104682792	104682792	A	T	SNP	TXNRD1	ENST00000429002	human	ensembl	74_37	+1	known	missense	c.388	p.I130L	0.062	superfamily_Thioredoxin-like_fold	pfam_Pyr_nucl-diS_OxRdtase_FAD/NAD,pfam_Pyr_nucl-diS_OxRdtase_dimer,pfam_Pyr_OxRdtase_NAD-bd_dom,pfam_FAD_bind_dom,pfam_Glutaredoxin,superfamily_FAD/NAD-linked_Rdtase_dimer,superfamily_Thioredoxin-like_fold,prints_FAD_pyr_nucl-diS_OxRdtase,prints_Hg_reductase,prints_Pyridine_nuc-diS_OxRdtase_2,tigrfam_Thioredoxin/glutathione_Rdtase	-	no_errors	TXNRD1	HGNC	ENSG00000198431	tier1	-	-	36	0	0.00	9	17	65.38
TYMS	0	genome.wustl.edu	37	18	671442	671442	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	18	671442	671442	G	A	SNP	TYMS	ENST00000323274	human	ensembl	74_37	+1	known	silent	c.795	p.L265	0.938	pfam_Thymidylate_synthase,superfamily_Thymidate_synth/dCMP_Mease,tigrfam_Thymidylate_synthase	pfam_Thymidylate_synthase,superfamily_Thymidate_synth/dCMP_Mease,prints_Thymidylate_synthase,tigrfam_Thymidylate_synthase	-	no_errors	TYMS	HGNC	ENSG00000176890	tier1	-	-	71	0	0.00	76	7	8.43
UBE2G2	0	genome.wustl.edu	37	21	46207977	46207977	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	21	46207977	46207977	G	T	SNP	UBE2G2	ENST00000345496	human	ensembl	74_37	-1	known	missense	c.77	p.A26E	1.000	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	-	no_errors	UBE2G2	HGNC	ENSG00000184787	tier1	-	-	40	0	0.00	36	4	10.00
UNC13C	0	genome.wustl.edu	37	15	54308000	54308000	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	15	54308000	54308000	G	T	SNP	UNC13C	ENST00000260323	human	ensembl	74_37	+1	known	missense	c.2900	p.R967I	0.998	NULL	pfam_Munc13_subgr_dom-2,pfam_Ca-dep_secretion_activator,pfam_C2_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,prints_C2_dom	-	no_errors	UNC13C	HGNC	ENSG00000137766				32	0	0.00	21	2	8.70
VARS2	0	genome.wustl.edu	37	6	30888139	30888139	+	Silent	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	6	30888139	30888139	G	A	SNP	VARS2	ENST00000541562	human	ensembl	74_37	+1	known	silent	c.1413	p.K471	0.812	pfam_aa-tRNA-synth_Ia,superfamily_Val/Leu/Ile-tRNA-synth_edit,tigrfam_Valyl-tRNA_ligase	pfam_aa-tRNA-synth_Ia,pfam_V/L/I-tRNA-synth_anticodon-bd,pfam_Methionyl/Leucyl_tRNA_Synth,superfamily_Val/Leu/Ile-tRNA-synth_edit,superfamily_tRNAsynth_1a_anticodon-bd,prints_Valyl-tRNA_ligase,tigrfam_Valyl-tRNA_ligase	-	no_errors	VARS2	HGNC	ENSG00000137411	tier1	-	-	17	0	0.00	13	6	31.58
VCAN	0	genome.wustl.edu	37	5	82837230	82837230	+	Missense_Mutation	SNP	A	A	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	82837230	82837230	A	G	SNP	VCAN	ENST00000265077	human	ensembl	74_37	+1	known	missense	c.8408	p.N2803S	0.000	NULL	pfam_Link,pfam_C-type_lectin,pfam_Ig_V-set,pfam_EG-like_dom,pfam_Sushi_SCR_CCP,superfamily_C-type_lectin_fold,superfamily_Sushi_SCR_CCP,smart_Ig_sub,smart_Link,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_C-type_lectin,smart_Sushi_SCR_CCP,pfscan_EG-like_dom,pfscan_C-type_lectin,pfscan_Link,pfscan_Sushi_SCR_CCP,pfscan_Ig-like_dom,prints_Link	-	no_errors	VCAN	HGNC	ENSG00000038427	tier1	-	-	27	0	0.00	22	17	43.59
WBP4	0	genome.wustl.edu	37	13	41654920	41654920	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	13	41654920	41654920	G	A	SNP	WBP4	ENST00000379487	human	ensembl	74_37	+1	known	missense	c.895	p.E299K	1.000	NULL	pfam_WW_dom,pfam_Znf_U1-C,superfamily_WW_dom,smart_Znf_U1,smart_WW_dom,pfscan_WW_dom,pfscan_Znf_C2H2_matrin	-	no_errors	WBP4	HGNC	ENSG00000120688	tier1	-	-	42	0	0.00	32	4	11.11
WDR33	0	genome.wustl.edu	37	2	128520663	128520663	+	Missense_Mutation	SNP	G	G	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	128520663	128520663	G	A	SNP	WDR33	ENST00000322313	human	ensembl	74_37	-1	known	missense	c.697	p.R233C	1.000	superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,pfam_Collagen,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDR33	HGNC	ENSG00000136709				21	0	0.00	27	4	12.90
XPOT	0	genome.wustl.edu	37	12	64823865	64823865	+	Nonsense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	12	64823865	64823865	C	T	SNP	XPOT	ENST00000332707	human	ensembl	74_37	+1	known	nonsense	c.1774	p.Q592*	1.000	superfamily_ARM-type_fold	pfam_Exportin-1/Importin-b-like,pfam_Importin-beta_N,superfamily_ARM-type_fold,smart_Importin-beta_N	-	no_errors	XPOT	HGNC	ENSG00000184575	tier1	-	-	45	0	0.00	125	14	10.00
YEATS2	0	genome.wustl.edu	37	3	183495460	183495460	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	3	183495460	183495460	C	T	SNP	YEATS2	ENST00000305135	human	ensembl	74_37	+1	known	missense	c.2708	p.S903F	1.000	NULL	pfam_YEATS,pfscan_YEATS	-	no_errors	YEATS2	HGNC	ENSG00000163872				27	0	0.00	51	3	5.56
YWHAQ	0	genome.wustl.edu	37	2	9725328	9725328	+	RNA	SNP	T	T	C			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	9725328	9725328	T	C	SNP	YWHAQ	ENST00000474715	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.999	-	-	-	no_errors	YWHAQ	HGNC	ENSG00000134308	tier1	-	-	28	0	0.00	38	20	34.48
ZFYVE1	0	genome.wustl.edu	37	14	73436427	73436427	+	Silent	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	14	73436427	73436427	C	T	SNP	ZFYVE1	ENST00000553891	human	ensembl	74_37	-1	known	silent	c.2361	p.P787	0.964	NULL	pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,superfamily_P-loop_NTPase,superfamily_Growth_fac_rcpt_N_dom,smart_Znf_FYVE,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE1	HGNC	ENSG00000165861	tier1	-	-	54	0	0.00	54	4	6.90
ZFYVE16	0	genome.wustl.edu	37	5	79733702	79733702	+	Nonsense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	79733702	79733702	C	T	SNP	ZFYVE16	ENST00000338008	human	ensembl	74_37	+1	known	nonsense	c.1198	p.Q400*	0.016	pirsf_Znf_FYVE_SARA/endofin	pfam_DUF3480,pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pirsf_Znf_FYVE_SARA/endofin,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE16	HGNC	ENSG00000039319	tier1	-	-	21	0	0.00	34	11	24.44
ZFYVE16	0	genome.wustl.edu	37	5	79733788	79733788	+	Missense_Mutation	SNP	C	C	G			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	5	79733788	79733788	C	G	SNP	ZFYVE16	ENST00000338008	human	ensembl	74_37	+1	known	missense	c.1284	p.F428L	0.000	pirsf_Znf_FYVE_SARA/endofin	pfam_DUF3480,pfam_Znf_FYVE,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pirsf_Znf_FYVE_SARA/endofin,pfscan_Znf_FYVE-rel	-	no_errors	ZFYVE16	HGNC	ENSG00000039319	tier1	-	-	18	0	0.00	36	9	20.00
ZNF462	0	genome.wustl.edu	37	9	109686919	109686919	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	9	109686919	109686919	C	A	SNP	ZNF462	ENST00000457913	human	ensembl	74_37	+1	known	missense	c.726	p.N242K	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF462	HGNC	ENSG00000148143	tier1	-	-	17	0	0.00	23	24	51.06
ZNF469	0	genome.wustl.edu	37	16	88505440	88505440	+	Silent	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	16	88505440	88505440	C	A	SNP	ZNF469	ENST00000437464	human	ensembl	74_37	+1	known	silent	c.11478	p.P3826	0.001	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF469	HGNC	ENSG00000225614	tier1	-	-	24	0	0.00	39	9	18.75
ZNF534	0	genome.wustl.edu	37	19	52941771	52941771	+	Missense_Mutation	SNP	C	C	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	19	52941771	52941771	C	T	SNP	ZNF534	ENST00000332323	human	ensembl	74_37	+1	known	missense	c.1097	p.P366L	0.706	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF534	HGNC	ENSG00000198633	tier1	-	-	21	0	0.00	21	23	52.27
ZNF638	0	genome.wustl.edu	37	2	71635285	71635285	+	Missense_Mutation	SNP	C	C	A			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	71635285	71635285	C	A	SNP	ZNF638	ENST00000264447	human	ensembl	74_37	+1	known	missense	c.3169	p.Q1057K	1.000	NULL	pfam_RRM_dom,smart_Znf_U1,smart_Znf_C2H2-like,smart_RRM_dom,pfscan_Znf_C2H2_matrin,pfscan_RRM_dom	-	no_errors	ZNF638	HGNC	ENSG00000075292	tier1	-	-	45	0	0.00	38	4	9.52
ZNF804A	0	genome.wustl.edu	37	2	185803049	185803049	+	Missense_Mutation	SNP	G	G	T			TCGA-S8-A6BW-01A-11D-A31U-09	TCGA-S8-A6BW-10A-01D-A31U-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	db39105a-4a30-4485-a1d9-4b0b0f055efa	25fe2333-04a2-4bd5-9f40-108703ff4e45	2	185803049	185803049	G	T	SNP	ZNF804A	ENST00000302277	human	ensembl	74_37	+1	known	missense	c.2926	p.A976S	0.998	NULL	pfam_Znf_C2H2_jaz	-	no_errors	ZNF804A	HGNC	ENSG00000170396	tier1	-	-	24	0	0.00	20	5	20.00
