Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ABCA9	0	genome.wustl.edu	37	17	66992115	66992115	+	Missense_Mutation	SNP	T	T	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	66992115	66992115	T	G	SNP	ABCA9	ENST00000340001	human	ensembl	74_37	-1	known	missense	c.3476	p.Y1159S	0.001	NULL	pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCA9	HGNC	ENSG00000154258	tier1	-	-	62	0	0.00	52	8	13.33
ABCG2	0	genome.wustl.edu	37	4	89061143	89061143	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	89061143	89061143	G	A	SNP	ABCG2	ENST00000237612	human	ensembl	74_37	-1	known	missense	c.5	p.S2F	0.973	NULL	pfam_ABC_2_trans,pfam_ABC_transporter-like,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like	-	no_errors	ABCG2	HGNC	ENSG00000118777				30	0	0.00	26	2	7.14
ACACB	0	genome.wustl.edu	37	12	109610096	109610096	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	109610096	109610096	G	A	SNP	ACACB	ENST00000338432	human	ensembl	74_37	+1	known	nonsense	c.1052	p.W351*	1.000	pfam_CarbamoylP_synth_lsu_N,superfamily_PreATP-grasp_dom,pfscan_Biotin_carboxylation_dom	pfam_AcCoA_COase_cen,pfam_Carboxyl_trans,pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_CarbamoylP_synth_lsu_N,pfam_Biotin_COase_C,pfam_Biotin_lipoyl,superfamily_PreATP-grasp_dom,superfamily_Rudment_hybrid_motif,superfamily_Single_hybrid_motif,smart_Biotin_COase_C,pfscan_ATP-grasp,pfscan_Biotin_carboxylation_dom,pfscan_COA_CT_N,pfscan_COA_CT_C,pfscan_Biotin_lipoyl	-	no_errors	ACACB	HGNC	ENSG00000076555	tier1	-	-	51	0	0.00	56	4	6.67
ACSM3	0	genome.wustl.edu	37	16	20787204	20787204	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	16	20787204	20787204	G	T	SNP	ACSM3	ENST00000289416	human	ensembl	74_37	+1	known	missense	c.263	p.R88I	0.008	NULL	pfam_AMP-dep_Synth/Lig	-	no_errors	ACSM3	HGNC	ENSG00000005187				44	0	0.00	35	2	5.41
ACTA1	0	genome.wustl.edu	37	1	229567270	229567270	+	Silent	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	229567270	229567270	G	T	SNP	ACTA1	ENST00000366684	human	ensembl	74_37	-1	known	silent	c.1110	p.S370	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTA1	HGNC	ENSG00000143632	tier1	-	-	41	0	0.00	37	21	36.21
ADRA1A	0	genome.wustl.edu	37	8	26721840	26721840	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	8	26721840	26721840	C	T	SNP	ADRA1A	ENST00000380586	human	ensembl	74_37	-1	known	missense	c.647	p.R216Q	0.983	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_ADRA1A_rcpt,prints_GPCR_Rhodpsn,prints_ADR_fam	-	no_errors	ADRA1A	HGNC	ENSG00000120907	tier1	-	-	44	0	0.00	48	4	7.69
AGAP1	0	genome.wustl.edu	37	2	237032618	237032618	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	237032618	237032618	C	T	SNP	AGAP1	ENST00000304032	human	ensembl	74_37	+1	known	missense	c.2426	p.A809V	1.000	superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	pfam_ArfGAP,pfam_MIRO-like,pfam_Small_GTPase,pfam_Ankyrin_rpt,pfam_Pleckstrin_homology,superfamily_P-loop_NTPase,superfamily_Ankyrin_rpt-contain_dom,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Pleckstrin_homology,smart_ArfGAP,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Pleckstrin_homology,pfscan_ArfGAP,prints_ArfGAP,prints_Small_GTPase	-	no_errors	AGAP1	HGNC	ENSG00000157985	tier1	-	-	140	0	0.00	103	39	27.46
AGBL5	0	genome.wustl.edu	37	2	27275949	27275949	+	Silent	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	27275949	27275949	C	A	SNP	AGBL5	ENST00000360131	human	ensembl	74_37	+1	known	silent	c.123	p.A41	0.975	NULL	pfam_Peptidase_M14	-	no_errors	AGBL5	HGNC	ENSG00000084693	tier1	-	-	55	0	0.00	32	15	31.91
AGTR2	0	genome.wustl.edu	37	X	115304321	115304321	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	115304321	115304321	T	C	SNP	AGTR2	ENST00000371906	human	ensembl	74_37	+1	known	missense	c.788	p.L263P	0.999	pfam_GPCR_Rhodpsn,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,prints_ATII_AT2_rcpt,prints_GPCR_Rhodpsn,prints_ATII_rcpt,prints_Brdyknn_rcpt,prints_Chemokine_rcpt,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	AGTR2	HGNC	ENSG00000180772	tier1	-	-	23	0	0.00	24	9	27.27
AIM2	0	genome.wustl.edu	37	1	159032497	159032497	+	Silent	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	159032497	159032497	G	T	SNP	AIM2	ENST00000368130	human	ensembl	74_37	-1	known	silent	c.1017	p.A339	0.000	NULL	pfam_HIN200/IF120x,pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_NA-bd_OB-fold,pfscan_DAPIN,pfscan_HIN200/IF120x	-	no_errors	AIM2	HGNC	ENSG00000163568				43	0	0.00	68	4	5.56
ALDH4A1	0	genome.wustl.edu	37	1	19203999	19203999	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	19203999	19203999	C	A	SNP	ALDH4A1	ENST00000290597	human	ensembl	74_37	-1	known	missense	c.1048	p.A350S	0.999	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_1-pyrroline-5-COlate_DH	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH,tigrfam_1-pyrroline-5-COlate_DH	-	no_errors	ALDH4A1	HGNC	ENSG00000159423				33	0	0.00	30	2	6.25
AMPD2	0	genome.wustl.edu	37	1	110172511	110172511	+	Frame_Shift_Del	DEL	C	C	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	110172511	110172511	C	-	DEL	AMPD2	ENST00000256578	human	ensembl	74_37	+1	known	frame_shift_del	c.2118	p.N706fs	1.000	pfam_A/AMP_deaminase_dom,pirsf_AMP_deaminase,tigrfam_AMP_deaminase	pfam_A/AMP_deaminase_dom,pirsf_AMP_deaminase,tigrfam_AMP_deaminase	-	no_errors	AMPD2	HGNC	ENSG00000116337	tier1			91	0	0.00	87	25	22.32
AMY2B	0	genome.wustl.edu	37	1	104118225	104118225	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	104118225	104118225	C	T	SNP	AMY2B	ENST00000462971	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	AMY2B	HGNC	ENSG00000240038	tier1	-	-	40	0	0.00	35	14	28.57
ANKRD23	0	genome.wustl.edu	37	2	97508119	97508119	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	97508119	97508119	C	T	SNP	ANKRD23	ENST00000318357	human	ensembl	74_37	-1	known	missense	c.157	p.E53K	0.976	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ANKRD23	HGNC	ENSG00000163126	tier1	-	-	87	0	0.00	61	37	37.76
ANXA11	0	genome.wustl.edu	37	10	81918943	81918943	+	Nonsense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	81918943	81918943	C	A	SNP	ANXA11	ENST00000265447	human	ensembl	74_37	-1	known	nonsense	c.1189	p.E397*	1.000	pfam_Annexin_repeat,smart_Annexin_repeat,prints_AnnexinVII	pfam_Annexin_repeat,smart_Annexin_repeat,prints_Annexin,prints_AnnexinXI,prints_AnnexinVII	-	no_errors	ANXA11	HGNC	ENSG00000122359	tier1	-	-	29	0	0.00	27	4	12.90
ANXA11	0	genome.wustl.edu	37	10	81918942	81918942	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	81918942	81918942	T	A	SNP	ANXA11	ENST00000265447	human	ensembl	74_37	-1	known	missense	c.1190	p.E397V	1.000	pfam_Annexin_repeat,smart_Annexin_repeat,prints_AnnexinVII	pfam_Annexin_repeat,smart_Annexin_repeat,prints_Annexin,prints_AnnexinXI,prints_AnnexinVII	-	no_errors	ANXA11	HGNC	ENSG00000122359				28	0	0.00	26	3	10.34
APC	0	genome.wustl.edu	37	5	112175259	112175259	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	112175259	112175259	T	A	SNP	APC	ENST00000257430	human	ensembl	74_37	+1	known	missense	c.3968	p.V1323D	0.995	NULL	pfam_APC_basic_dom,pfam_EB1-bd,pfam_APC_Cys-rich_rpt,pfam_Armadillo,pfam_APC_dom,pfam_SAMP,pfam_APC_15aa_rpt,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	APC	HGNC	ENSG00000134982				39	0	0.00	34	2	5.56
APC	0	genome.wustl.edu	37	5	112175285	112175285	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	112175285	112175285	A	G	SNP	APC	ENST00000257430	human	ensembl	74_37	+1	known	missense	c.3994	p.T1332A	1.000	NULL	pfam_APC_basic_dom,pfam_EB1-bd,pfam_APC_Cys-rich_rpt,pfam_Armadillo,pfam_APC_dom,pfam_SAMP,pfam_APC_15aa_rpt,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	APC	HGNC	ENSG00000134982				39	0	0.00	34	2	5.56
APOB	0	genome.wustl.edu	37	2	21233395	21233395	+	Silent	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	21233395	21233395	C	A	SNP	APOB	ENST00000233242	human	ensembl	74_37	-1	known	silent	c.6345	p.L2115	0.025	NULL	pfam_Lipid_transpt_N,pfam_Vitellinogen_open_b-sht,pfam_ApoB100_C,pfam_Lipid_transpt_open_b-sht,superfamily_Lipid_transp_b-sht_shell,superfamily_Vitellinogen_superhlx,superfamily_ARM-type_fold,smart_Lipid_transpt_N,pfscan_Lipid_transpt_N	-	no_errors	APOB	HGNC	ENSG00000084674				32	0	0.00	32	2	5.88
ARHGAP28	0	genome.wustl.edu	37	18	6912058	6912058	+	Splice_Site	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	18	6912058	6912058	G	T	SNP	ARHGAP28	ENST00000314319	human	ensembl	74_37	+1	known	splice_site	c.1619-1	e16-1	1.000	-	-	-	no_errors	ARHGAP28	HGNC	ENSG00000088756				19	0	0.00	24	5	17.24
ARHGAP6	0	genome.wustl.edu	37	X	11206970	11206970	+	Nonsense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	11206970	11206970	C	A	SNP	ARHGAP6	ENST00000337414	human	ensembl	74_37	-1	known	nonsense	c.955	p.G319*	1.000	NULL	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP6	HGNC	ENSG00000047648	tier1	-	-	22	0	0.00	19	4	17.39
ARL6IP6	0	genome.wustl.edu	37	2	153577006	153577006	+	RNA	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	153577006	153577006	T	C	SNP	ARL6IP6	ENST00000463690	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	ARL6IP6	HGNC	ENSG00000177917	tier1	-	-	50	0	0.00	53	18	25.35
ATP10B	0	genome.wustl.edu	37	5	160049468	160049468	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	160049468	160049468	T	A	SNP	ATP10B	ENST00000327245	human	ensembl	74_37	-1	known	missense	c.1745	p.D582V	1.000	superfamily_HAD-like_dom,tigrfam_ATPase_P-typ_Plipid-transp	pfam_ATPase_P-typ_transduc_dom_A,pfam_HAD-like_dom,superfamily_HAD-like_dom,superfamily_ATPase_P-typ_cyto_domN,prints_Cation_transp_P_typ_ATPase,tigrfam_ATPase_P-typ_Plipid-transp,tigrfam_Cation_transp_P_typ_ATPase	-	no_errors	ATP10B	HGNC	ENSG00000118322	tier1	-	-	48	0	0.00	20	19	48.72
AXIN2	0	genome.wustl.edu	37	17	63532605	63532605	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	63532605	63532605	G	A	SNP	AXIN2	ENST00000307078	human	ensembl	74_37	-1	known	silent	c.1974	p.S658	0.713	NULL	pfam_DIX,pfam_RGS_dom,pfam_Axin_b-cat-bd,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,smart_DIX,pfscan_DIX,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	AXIN2	HGNC	ENSG00000168646	tier1	-	-	44	0	0.00	28	4	12.50
BIRC6	0	genome.wustl.edu	37	2	32661251	32661251	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	32661251	32661251	A	T	SNP	BIRC6	ENST00000421745	human	ensembl	74_37	+1	known	missense	c.3630	p.K1210N	1.000	NULL	pfam_DUF3643,pfam_UBQ-conjugat_E2,pfam_BIR,pfam_UEV_N,superfamily_UBQ-conjugating_enzyme/RWD,superfamily_Galactose-bd-like,superfamily_WD40_repeat_dom,smart_BIR,pfscan_BIR,pfscan_UBQ-conjugat_E2	-	no_errors	BIRC6	HGNC	ENSG00000115760	tier1	-	-	77	0	0.00	90	11	10.89
BPIFA2	0	genome.wustl.edu	37	20	31767414	31767414	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	31767414	31767414	G	T	SNP	BPIFA2	ENST00000253362	human	ensembl	74_37	+1	known	missense	c.650	p.C217F	0.144	pfam_Lipid-bd_serum_glycop_N,superfamily_Bactericidal_perm-incr_a/b_dom	pfam_Lipid-bd_serum_glycop_N,superfamily_Bactericidal_perm-incr_a/b_dom	-	no_errors	BPIFA2	HGNC	ENSG00000131050				45	0	0.00	59	4	6.35
C12orf50	0	genome.wustl.edu	37	12	88388500	88388500	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	88388500	88388500	T	A	SNP	C12orf50	ENST00000298699	human	ensembl	74_37	-1	known	missense	c.502	p.T168S	1.000	NULL	NULL	-	no_errors	C12orf50	HGNC	ENSG00000165805	tier1	-	-	67	0	0.00	69	4	5.48
CADM1	0	genome.wustl.edu	37	11	115049492	115049492	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	115049492	115049492	G	A	SNP	CADM1	ENST00000452722	human	ensembl	74_37	-1	known	missense	c.1082	p.S361F	1.000	NULL	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,pfam_CD80_C2-set,smart_Ig_sub,smart_Ig_sub2,smart_Neurexin-like,pfscan_Ig-like_dom	-	no_errors	CADM1	HGNC	ENSG00000182985	tier1	-	-	38	0	0.00	30	6	16.67
CBX6	0	genome.wustl.edu	37	22	39262318	39262318	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	22	39262318	39262318	T	C	SNP	CBX6	ENST00000407418	human	ensembl	74_37	-1	known	missense	c.1135	p.T379A	1.000	NULL	pfam_Chromo_domain,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,pfscan_Chromo_domain/shadow,prints_Chromo_dom_subgr	-	no_errors	CBX6	HGNC	ENSG00000183741	tier1	-	-	86	0	0.00	70	4	5.41
CCDC109B	0	genome.wustl.edu	37	4	110606473	110606473	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	110606473	110606473	C	G	SNP	CCDC109B	ENST00000394650	human	ensembl	74_37	+1	known	missense	c.883	p.Q295E	0.000	pfam_Coiled-coil-dom_prot_109_C	pfam_Coiled-coil-dom_prot_109_C	-	no_errors	CCDC109B	HGNC	ENSG00000005059	tier1	-	-	49	0	0.00	36	4	10.00
CCDC110	0	genome.wustl.edu	37	4	186380437	186380437	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	186380437	186380437	A	T	SNP	CCDC110	ENST00000307588	human	ensembl	74_37	-1	known	missense	c.1304	p.L435Q	0.825	NULL	superfamily_4_helix_cytokine-like_core	-	no_errors	CCDC110	HGNC	ENSG00000168491				29	0	0.00	31	3	8.82
CCDC169	0	genome.wustl.edu	37	13	36869957	36869957	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	36869957	36869957	T	C	SNP	CCDC169	ENST00000239859	human	ensembl	74_37	-1	known	missense	c.121	p.K41E	0.997	NULL	NULL	-	no_errors	CCDC169	HGNC	ENSG00000242715				60	0	0.00	52	4	7.14
CCDC37	0	genome.wustl.edu	37	3	126155278	126155278	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	126155278	126155278	G	T	SNP	CCDC37	ENST00000506204	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	CCDC37	HGNC	ENSG00000163885	tier1	-	-	37	0	0.00	34	4	10.53
CCDC74A	0	genome.wustl.edu	37	2	132287653	132287653	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	132287653	132287653	C	G	SNP	CCDC74A	ENST00000467992	human	ensembl	74_37	+1	known	missense	c.103	p.H35D	0.000	NULL	NULL	-	no_errors	CCDC74A	HGNC	ENSG00000163040				70	0	0.00	90	5	5.26
CCNYL2	0	genome.wustl.edu	37	10	42965691	42965691	+	RNA	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	42965691	42965691	T	C	SNP	CCNYL2	ENST00000483242	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CCNYL2	HGNC	ENSG00000182632	tier1	-	-	52	0	0.00	46	8	14.81
CD3E	0	genome.wustl.edu	37	11	118175687	118175687	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	118175687	118175687	G	T	SNP	CD3E	ENST00000361763	human	ensembl	74_37	+1	known	missense	c.20	p.W7L	0.997	NULL	pfam_Phos_immunorcpt_sig_ITAM,smart_Ig_sub2,smart_Phos_immunorcpt_sig_ITAM,pfscan_Phos_immunorcpt_sig_ITAM	-	no_errors	CD3E	HGNC	ENSG00000198851	tier1	-	-	41	0	0.00	39	4	9.30
CEBPZ	0	genome.wustl.edu	37	2	37428939	37428939	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	37428939	37428939	T	C	SNP	CEBPZ	ENST00000234170	human	ensembl	74_37	-1	known	missense	c.3133	p.T1045A	0.001	NULL	pfam_CCAAT-binding_factor,superfamily_ARM-type_fold	-	no_errors	CEBPZ	HGNC	ENSG00000115816	tier1	-	-	47	0	0.00	47	23	32.86
CENPJ	0	genome.wustl.edu	37	13	25480757	25480757	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	25480757	25480757	C	T	SNP	CENPJ	ENST00000381884	human	ensembl	74_37	-1	known	silent	c.1419	p.L473	0.017	NULL	pfam_Tcp10_C_dom	-	no_errors	CENPJ	HGNC	ENSG00000151849				32	0	0.00	39	4	9.30
CHCHD6	0	genome.wustl.edu	37	3	126423151	126423151	+	RNA	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	126423151	126423151	T	C	SNP	CHCHD6	ENST00000514908	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.055	-	-	-	no_errors	CHCHD6	HGNC	ENSG00000159685	tier1	-	-	43	0	0.00	42	5	10.64
CHST10	0	genome.wustl.edu	37	2	101010094	101010094	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	101010094	101010094	G	A	SNP	CHST10	ENST00000542617	human	ensembl	74_37	-1	known	silent	c.828	p.N276	1.000	pfam_Sulfotransferase,superfamily_P-loop_NTPase	pfam_Sulfotransferase,superfamily_P-loop_NTPase	-	no_errors	CHST10	HGNC	ENSG00000115526				31	0	0.00	32	4	11.11
CIC	0	genome.wustl.edu	37	19	42791176	42791177	+	Frame_Shift_Ins	INS	-	-	TGTT			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	42791176	42791177	-	TGTT	INS	CIC	ENST00000575354	human	ensembl	74_37	+1	known	frame_shift_ins	c.236_237	p.A81fs	0.970:0.968	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	CIC	HGNC	ENSG00000079432	tier1			84	0	0.00	49	25	33.78
CLDN15	0	genome.wustl.edu	37	7	100877648	100877648	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	100877648	100877648	G	A	SNP	CLDN15	ENST00000308344	human	ensembl	74_37	-1	known	missense	c.293	p.A98V	0.306	pfam_PMP22/EMP/MP20/Claudin,prints_Claudin	pfam_PMP22/EMP/MP20/Claudin,prints_Claudin,prints_Claudin15	-	no_errors	CLDN15	HGNC	ENSG00000106404	tier1	-	-	42	0	0.00	47	4	7.84
CLEC4A	0	genome.wustl.edu	37	12	8276480	8276480	+	Silent	SNP	T	T	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	8276480	8276480	T	G	SNP	CLEC4A	ENST00000229332	human	ensembl	74_37	+1	known	silent	c.6	p.T2	0.001	NULL	pfam_C-type_lectin,superfamily_C-type_lectin_fold,smart_C-type_lectin,pfscan_C-type_lectin,prints_AntifreezeII	-	no_errors	CLEC4A	HGNC	ENSG00000111729	tier1	-	-	37	0	0.00	18	27	60.00
CMYA5	0	genome.wustl.edu	37	5	79030465	79030465	+	Silent	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	79030465	79030465	A	G	SNP	CMYA5	ENST00000446378	human	ensembl	74_37	+1	known	silent	c.5877	p.Q1959	0.031	NULL	pfam_Fibronectin_type3,pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_B30.2/SPRY,pfscan_Fibronectin_type3	-	no_errors	CMYA5	HGNC	ENSG00000164309	tier1	-	-	23	0	0.00	18	10	35.71
CNNM4	0	genome.wustl.edu	37	2	97427122	97427122	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	97427122	97427122	C	A	SNP	CNNM4	ENST00000377075	human	ensembl	74_37	+1	known	missense	c.386	p.S129Y	0.998	NULL	pfam_DUF21,pfam_CBS_dom,superfamily_cNMP-bd-like,pfscan_cNMP-bd_dom	-	no_errors	CNNM4	HGNC	ENSG00000158158	tier1	-	-	25	0	0.00	18	7	28.00
CNOT2	0	genome.wustl.edu	37	12	70738008	70738008	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	70738008	70738008	T	C	SNP	CNOT2	ENST00000229195	human	ensembl	74_37	+1	known	missense	c.1391	p.L464P	1.000	pfam_NOT	pfam_NOT	-	no_errors	CNOT2	HGNC	ENSG00000111596	tier1	-	-	46	0	0.00	57	8	12.31
CNTNAP1	0	genome.wustl.edu	37	17	40842780	40842780	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	40842780	40842780	C	T	SNP	CNTNAP1	ENST00000264638	human	ensembl	74_37	+1	known	missense	c.1879	p.R627W	0.246	superfamily_Fibrinogen_a/b/g_C_dom	pfam_Laminin_G,pfam_Coagulation_fac_5/8-C_type_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Galactose-bd-like,superfamily_Fibrinogen_a/b/g_C_dom,smart_Coagulation_fac_5/8-C_type_dom,smart_Laminin_G,smart_Neurexin-like,pfscan_EG-like_dom,pfscan_Coagulation_fac_5/8-C_type_dom,pfscan_Laminin_G	-	no_errors	CNTNAP1	HGNC	ENSG00000108797				34	0	0.00	39	3	6.82
COL4A2	0	genome.wustl.edu	37	13	111077333	111077333	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	111077333	111077333	G	A	SNP	COL4A2	ENST00000360467	human	ensembl	74_37	+1	known	missense	c.349	p.D117N	0.998	pfam_Collagen	pfam_Collagen,pfam_Collagen_VI_NC,superfamily_C-type_lectin_fold,smart_Collagen_VI_NC	-	no_errors	COL4A2	HGNC	ENSG00000134871				74	0	0.00	58	4	6.45
CPED1	0	genome.wustl.edu	37	7	120782104	120782104	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	120782104	120782104	A	G	SNP	CPED1	ENST00000310396	human	ensembl	74_37	+1	known	missense	c.1964	p.E655G	0.017	NULL	NULL	-	no_errors	CPED1	HGNC	ENSG00000106034	tier1	-	-	73	0	0.00	89	8	8.16
CROCCP2	0	genome.wustl.edu	37	1	16945227	16945227	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	16945227	16945227	G	T	SNP	CROCCP2	ENST00000412962	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	CROCCP2	HGNC	ENSG00000215908	tier1	rs9728628	-	17	0	0.00	13	4	23.53
CROCCP2	0	genome.wustl.edu	37	1	16946164	16946164	+	RNA	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	16946164	16946164	A	G	SNP	CROCCP2	ENST00000412962	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.012	-	-	-	no_errors	CROCCP2	HGNC	ENSG00000215908	tier1	rs59600364	-	14	0	0.00	17	6	26.09
CTNND2	0	genome.wustl.edu	37	5	10973545	10973545	+	RNA	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	10973545	10973545	G	A	SNP	CTNND2	ENST00000495388	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.924	-	-	-	no_errors	CTNND2	HGNC	ENSG00000169862	tier1	-	-	53	0	0.00	93	15	13.89
DCAF17	0	genome.wustl.edu	37	2	172305295	172305295	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	172305295	172305295	G	T	SNP	DCAF17	ENST00000375255	human	ensembl	74_37	+1	known	missense	c.426	p.E142D	1.000	NULL	NULL	-	no_errors	DCAF17	HGNC	ENSG00000115827	tier1	-	-	85	0	0.00	60	7	10.45
DCAF17	0	genome.wustl.edu	37	2	172305296	172305296	+	Nonsense_Mutation	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	172305296	172305296	A	T	SNP	DCAF17	ENST00000375255	human	ensembl	74_37	+1	known	nonsense	c.427	p.K143*	1.000	NULL	NULL	-	no_errors	DCAF17	HGNC	ENSG00000115827	tier1	-	-	85	0	0.00	60	8	11.76
DGKB	0	genome.wustl.edu	37	7	14652969	14652969	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	14652969	14652969	C	T	SNP	DGKB	ENST00000258767	human	ensembl	74_37	-1	known	missense	c.1357	p.E453K	1.000	pfam_Diacylglycerol_kinase_cat_dom,smart_Diacylglycerol_kinase_cat_dom	pfam_Diacylglycerol_kin_accessory,pfam_Diacylglycerol_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,smart_EF_hand_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Diacylglycerol_kinase_cat_dom,smart_Diacylglycerol_kin_accessory,pfscan_EF_hand_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd	-	no_errors	DGKB	HGNC	ENSG00000136267	tier1	-	-	83	0	0.00	117	17	12.69
DHX8	0	genome.wustl.edu	37	17	41601024	41601024	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	41601024	41601024	A	G	SNP	DHX8	ENST00000262415	human	ensembl	74_37	+1	known	missense	c.3472	p.T1158A	1.000	pfam_DUF1605,superfamily_P-loop_NTPase	pfam_Helicase-assoc_dom,pfam_DUF1605,pfam_Rbsml_prot_S1_RNA-bd_dom,pfam_Helicase_C,pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,superfamily_NA-bd_OB-fold,smart_RNA-binding_domain_S1,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Helicase-assoc_dom,pfscan_Rbsml_prot_S1_RNA-bd_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DHX8	HGNC	ENSG00000067596	tier1	-	-	61	0	0.00	66	14	17.50
DNAH14	0	genome.wustl.edu	37	1	225237932	225237932	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	225237932	225237932	C	A	SNP	DNAH14	ENST00000430092	human	ensembl	74_37	+1	known	missense	c.1933	p.Q645K	0.999	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,superfamily_P-loop_NTPase,superfamily_Tautomerase/MIF_sf,smart_AAA+_ATPase	-	no_errors	DNAH14	HGNC	ENSG00000185842	tier1	-	-	61	0	0.00	58	67	53.60
DNAH5	0	genome.wustl.edu	37	5	13870950	13870950	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	13870950	13870950	G	C	SNP	DNAH5	ENST00000265104	human	ensembl	74_37	-1	known	missense	c.3760	p.R1254G	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DNAH5	HGNC	ENSG00000039139	tier1	-	-	75	0	0.00	114	32	21.92
DPYD-AS1	0	genome.wustl.edu	37	1	97771865	97771865	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	97771865	97771865	G	T	SNP	DPYD-AS1	ENST00000422980	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	DPYD-AS1	HGNC	ENSG00000232878	tier1	-	-	45	0	0.00	36	16	30.77
DROSHA	0	genome.wustl.edu	37	5	31424578	31424578	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	31424578	31424578	C	G	SNP	DROSHA	ENST00000344624	human	ensembl	74_37	-1	known	missense	c.3217	p.D1073H	1.000	superfamily_RNase_III_dom,smart_RNase_III_dom	pfam_RNase_III_dom,pfam_dsRNA-bd_dom,superfamily_RNase_III_dom,smart_RNase_III_dom,smart_dsRNA-bd_dom,pfscan_dsRNA-bd_dom,pfscan_RNase_III_dom	-	no_errors	DROSHA	HGNC	ENSG00000113360	tier1	-	-	47	0	0.00	94	9	8.74
DTHD1	0	genome.wustl.edu	37	4	36345331	36345331	+	Frame_Shift_Del	DEL	T	T	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	36345331	36345331	T	-	DEL	DTHD1	ENST00000456874	human	ensembl	74_37	+1	known	frame_shift_del	c.2231	p.L744fs	1.000	pfam_Death_domain,superfamily_DEATH-like_dom,pfscan_Death_domain	pfam_Death_domain,superfamily_DEATH-like_dom,pfscan_Death_domain	-	no_errors	DTHD1	HGNC	ENSG00000197057	tier1			26	0	0.00	10	7	41.18
DUS3L	0	genome.wustl.edu	37	19	5788046	5788046	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	5788046	5788046	A	G	SNP	DUS3L	ENST00000309061	human	ensembl	74_37	-1	known	missense	c.1084	p.F362L	1.000	pfam_tRNA_hU_synthase	pfam_tRNA_hU_synthase	-	no_errors	DUS3L	HGNC	ENSG00000141994	tier1	-	-	55	0	0.00	28	32	53.33
DYTN	0	genome.wustl.edu	37	2	207557996	207557996	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	207557996	207557996	G	T	SNP	DYTN	ENST00000452335	human	ensembl	74_37	-1	known	missense	c.883	p.L295I	0.387	NULL	pfam_EF-hand_dom_typ2,pfam_EF-hand_dom_typ1,pfam_Znf_ZZ,smart_Znf_ZZ,pfscan_Znf_ZZ	-	no_errors	DYTN	HGNC	ENSG00000232125				34	0	0.00	32	2	5.88
DZIP1	0	genome.wustl.edu	37	13	96282275	96282275	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	96282275	96282275	C	T	SNP	DZIP1	ENST00000347108	human	ensembl	74_37	-1	known	missense	c.778	p.A260T	0.262	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	DZIP1	HGNC	ENSG00000134874	tier1	-	-	43	0	0.00	46	4	8.00
EFNB3	0	genome.wustl.edu	37	17	7611541	7611541	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	7611541	7611541	C	T	SNP	EFNB3	ENST00000226091	human	ensembl	74_37	+1	known	missense	c.388	p.R130C	0.986	pfam_Ephrin,superfamily_Cupredoxin,prints_Ephrin	pfam_Ephrin,superfamily_Cupredoxin,prints_Ephrin	-	no_errors	EFNB3	HGNC	ENSG00000108947	tier1	-	-	47	0	0.00	50	4	7.41
EIF4A1	0	genome.wustl.edu	37	17	7479902	7479902	+	Frame_Shift_Del	DEL	G	G	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	7479902	7479902	G	-	DEL	EIF4A1	ENST00000293831	human	ensembl	74_37	+1	known	frame_shift_del	c.406	p.G137fs	1.000	pfam_DNA/RNA_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_RNA_helicase_DEAD_Q_motif	-	no_errors	EIF4A1	HGNC	ENSG00000161960	tier1			35	0	0.00	31	2	6.06
ELTD1	0	genome.wustl.edu	37	1	79383662	79383662	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	79383662	79383662	C	T	SNP	ELTD1	ENST00000370742	human	ensembl	74_37	-1	known	missense	c.1535	p.G512D	1.000	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	pfam_GPCR_2_secretin-like,pfam_DUF3497,pfam_GPS_dom,pfam_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_GPS_dom,pfscan_EG-like_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	-	no_errors	ELTD1	HGNC	ENSG00000162618				12	0	0.00	24	2	7.69
EMILIN3	0	genome.wustl.edu	37	20	39990470	39990470	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	39990470	39990470	A	G	SNP	EMILIN3	ENST00000332312	human	ensembl	74_37	-1	known	missense	c.1739	p.L580P	0.299	NULL	pfam_EMI_domain,pfscan_EMI_domain	-	no_errors	EMILIN3	HGNC	ENSG00000183798				33	0	0.00	37	4	9.76
EMR1	0	genome.wustl.edu	37	19	6937659	6937659	+	Silent	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	6937659	6937659	G	T	SNP	EMR1	ENST00000312053	human	ensembl	74_37	+1	known	silent	c.2655	p.T885	0.971	NULL	pfam_GPCR_2_secretin-like,pfam_EGF-like_Ca-bd_dom,pfam_GPS_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_GPS_dom,pfscan_EG-like_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_GPCR_2_EMR1_rcpt,prints_GPCR_2_secretin-like	-	no_errors	EMR1	HGNC	ENSG00000174837				24	0	0.00	29	4	12.12
ENSG00000221346	0	genome.wustl.edu	37	1	47968307	47968307	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	47968307	47968307	G	T	SNP	ENSG00000221346	ENST00000408419	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.002	-	-	-	no_errors	AL356458.1	Clone_based_ensembl_gene	ENSG00000221346	tier1	-	-	43	0	0.00	50	4	7.41
ENSG00000222899	0	genome.wustl.edu	37	14	27396981	27396981	+	RNA	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	27396981	27396981	T	A	SNP	ENSG00000222899	ENST00000410967	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.000	-	-	-	no_errors	AL110292.1	Clone_based_ensembl_gene	ENSG00000222899	tier1	-	-	200	0	0.00	133	70	34.48
ENSG00000244227	0	genome.wustl.edu	37	3	167638415	167638415	+	RNA	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	167638415	167638415	G	A	SNP	ENSG00000244227	ENST00000459923	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.092	-	-	-	no_errors	RP11-298O21.5	Clone_based_vega_gene	ENSG00000244227	tier1	-	-	71	0	0.00	64	25	28.09
EPSTI1	0	genome.wustl.edu	37	13	43537397	43537397	+	Silent	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	43537397	43537397	T	C	SNP	EPSTI1	ENST00000313640	human	ensembl	74_37	-1	known	silent	c.483	p.R161	1.000	NULL	NULL	-	no_errors	EPSTI1	HGNC	ENSG00000133106	tier1	rs150771459	-	85	0	0.00	66	9	12.00
EVL	0	genome.wustl.edu	37	14	100599115	100599115	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	100599115	100599115	T	C	SNP	EVL	ENST00000392920	human	ensembl	74_37	+1	known	missense	c.899	p.M300T	0.984	pirsf_Vasodilator_phosphoprotein	pfam_WH1/EVH1,pfam_VASP_tetra,smart_WH1/EVH1,pirsf_Vasodilator_phosphoprotein,pfscan_WH1/EVH1	-	no_errors	EVL	HGNC	ENSG00000196405	tier1	-	-	61	0	0.00	26	18	40.00
EXD2	0	genome.wustl.edu	37	14	69701736	69701736	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	69701736	69701736	G	A	SNP	EXD2	ENST00000312994	human	ensembl	74_37	+1	known	missense	c.1037	p.G346D	1.000	NULL	pfam_3'-5'_exonuclease_dom,superfamily_RNaseH-like_dom,smart_3'-5'_exonuclease_dom	-	no_errors	EXD2	HGNC	ENSG00000081177	tier1	-	-	37	0	0.00	33	4	10.81
FABP6	0	genome.wustl.edu	37	5	159640768	159640768	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	159640768	159640768	G	A	SNP	FABP6	ENST00000393980	human	ensembl	74_37	+1	known	missense	c.77	p.C26Y	0.000	NULL	superfamily_Calycin-like,prints_Fatty_acid-bd	-	no_errors	FABP6	HGNC	ENSG00000170231				45	0	0.00	37	2	5.13
FAM151A	0	genome.wustl.edu	37	1	55075032	55075032	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	55075032	55075032	A	G	SNP	FAM151A	ENST00000302250	human	ensembl	74_37	-1	known	missense	c.1667	p.L556P	0.997	pfam_DUF2181	pfam_DUF2181	-	no_errors	FAM151A	HGNC	ENSG00000162391				39	0	0.00	51	4	7.27
FAR1	0	genome.wustl.edu	37	11	13729559	13729559	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	13729559	13729559	C	T	SNP	FAR1	ENST00000354817	human	ensembl	74_37	+1	known	missense	c.478	p.R160C	1.000	pfam_Male_sterile_NAD-bd,pfam_Epimerase_deHydtase	pfam_Male_sterile_NAD-bd,pfam_FAR,pfam_Epimerase_deHydtase	-	no_errors	FAR1	HGNC	ENSG00000197601	tier1	-	-	55	0	0.00	63	4	5.97
FARP1	0	genome.wustl.edu	37	13	99083388	99083388	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	99083388	99083388	G	C	SNP	FARP1	ENST00000376586	human	ensembl	74_37	+1	known	missense	c.1997	p.R666T	0.733	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,pfscan_DH-domain	pfam_DH-domain,pfam_Pleckstrin_homology,pfam_FERM_PH-like_C,pfam_FERM_N,pfam_FERM-adjacent,pfam_FERM_central,superfamily_DH-domain,superfamily_FERM_central,smart_Band_41_domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_FERM_domain,pfscan_Pleckstrin_homology,pfscan_DH-domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	FARP1	HGNC	ENSG00000152767	tier1	-	-	36	0	0.00	17	11	39.29
FCRL5	0	genome.wustl.edu	37	1	157485719	157485719	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	157485719	157485719	G	T	SNP	FCRL5	ENST00000462218	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	FCRL5	HGNC	ENSG00000143297	tier1	-	-	19	0	0.00	12	10	45.45
FMO3	0	genome.wustl.edu	37	1	171086361	171086361	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	171086361	171086361	G	A	SNP	FMO3	ENST00000367755	human	ensembl	74_37	+1	known	missense	c.1378	p.E460K	0.996	pfam_Flavin_mOase-like,pirsf_DiMe-aniline_mOase	pfam_Flavin_mOase-like,pfam_Pyr_nucl-diS_OxRdtase_FAD/NAD,pirsf_DiMe-aniline_mOase,prints_Flavin_mOase,prints_Flavin_mOase_3,prints_Flavin_mOase_1,prints_Flavin_mOase_2	-	no_errors	FMO3	HGNC	ENSG00000007933	tier1	-	-	36	0	0.00	31	14	31.11
FOXJ1	0	genome.wustl.edu	37	17	74134094	74134094	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	74134094	74134094	C	T	SNP	FOXJ1	ENST00000322957	human	ensembl	74_37	-1	known	silent	c.606	p.A202	0.653	pfam_TF_fork_head,smart_TF_fork_head,pfscan_TF_fork_head	pfam_TF_fork_head,smart_TF_fork_head,prints_TF_fork_head,pfscan_TF_fork_head	-	no_errors	FOXJ1	HGNC	ENSG00000129654	tier1	-	-	66	0	0.00	50	8	13.79
FRAS1	0	genome.wustl.edu	37	4	79460559	79460559	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	79460559	79460559	G	A	SNP	FRAS1	ENST00000264895	human	ensembl	74_37	+1	known	missense	c.11410	p.D3804N	1.000	NULL	pfam_Calx_beta,pfam_VWF_C,superfamily_Growth_fac_rcpt_N_dom,superfamily_Cadherin-like,smart_VWC_out,smart_VWF_C,smart_Furin_repeat,smart_EG-like_dom,smart_Calx_beta,pfscan_VWF_C	-	no_errors	FRAS1	HGNC	ENSG00000138759	tier1	-	-	33	0	0.00	13	11	45.83
FREM2	0	genome.wustl.edu	37	13	39452315	39452315	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	39452315	39452315	C	A	SNP	FREM2	ENST00000280481	human	ensembl	74_37	+1	known	missense	c.8716	p.L2906M	1.000	NULL	pfam_Calx_beta,superfamily_Cadherin-like,smart_Calx_beta	-	no_errors	FREM2	HGNC	ENSG00000150893	tier1	-	-	54	0	0.00	73	4	5.13
FRMPD4	0	genome.wustl.edu	37	X	12734448	12734448	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	12734448	12734448	A	G	SNP	FRMPD4	ENST00000380682	human	ensembl	74_37	+1	known	missense	c.1870	p.S624G	0.122	NULL	pfam_FERM_central,pfam_PDZ,superfamily_FERM_central,superfamily_PDZ,smart_PDZ,smart_Band_41_domain,pfscan_FERM_domain,pfscan_PDZ,pfscan_WW_dom	-	no_errors	FRMPD4	HGNC	ENSG00000169933				14	0	0.00	4	7	63.64
FSIP2	0	genome.wustl.edu	37	2	186620970	186620970	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	186620970	186620970	C	G	SNP	FSIP2	ENST00000343098	human	ensembl	74_37	+1	known	missense	c.1310	p.P437R	0.012	NULL	NULL	-	no_errors	FSIP2	HGNC	ENSG00000188738	tier1	-	-	51	0	0.00	48	10	17.24
FTH1P10	0	genome.wustl.edu	37	5	17354553	17354553	+	RNA	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	17354553	17354553	G	A	SNP	FTH1P10	ENST00000401830	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.006	-	-	-	no_errors	FTH1P10	HGNC	ENSG00000223361	tier1	-	-	61	0	0.00	51	24	31.58
FTO	0	genome.wustl.edu	37	16	53967949	53967949	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	16	53967949	53967949	G	C	SNP	FTO	ENST00000471389	human	ensembl	74_37	+1	known	missense	c.1292	p.R431T	1.000	NULL	NULL	-	no_errors	FTO	HGNC	ENSG00000140718	tier1	-	-	84	0	0.00	30	32	51.61
GABRA6	0	genome.wustl.edu	37	5	161115980	161115980	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	161115980	161115980	G	A	SNP	GABRA6	ENST00000274545	human	ensembl	74_37	+1	known	missense	c.251	p.R84H	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,prints_Neur_channel,tigrfam_Neur_channel	pfam_Neur_chan_lig-bd,pfam_Neurotrans-gated_channel_TM,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAAa_rcpt,prints_GABAA_rcpt,prints_GABBAa6_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRA6	HGNC	ENSG00000145863				55	0	0.00	45	3	6.25
GABRB3	0	genome.wustl.edu	37	15	26806324	26806324	+	Splice_Site	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	15	26806324	26806324	C	A	SNP	GABRB3	ENST00000299267	human	ensembl	74_37	-1	known	splice_site	c.836-1	e8-1	1.000	-	-	-	no_errors	GABRB3	HGNC	ENSG00000166206				38	0	0.00	52	3	5.45
GBAP1	0	genome.wustl.edu	37	1	155185406	155185406	+	RNA	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	155185406	155185406	A	T	SNP	GBAP1	ENST00000368374	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	GBAP1	HGNC	ENSG00000160766	tier1	-	-	65	0	0.00	66	7	9.59
GCFC2	0	genome.wustl.edu	37	2	75921495	75921495	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	75921495	75921495	G	C	SNP	GCFC2	ENST00000321027	human	ensembl	74_37	-1	known	missense	c.892	p.Q298E	0.018	NULL	pfam_GCFC_dom	-	no_errors	GCFC2	HGNC	ENSG00000005436	tier1	-	-	72	0	0.00	85	10	10.53
GNN	0	genome.wustl.edu	37	12	104283269	104283269	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	104283269	104283269	C	T	SNP	GNN	ENST00000548520	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.094	-	-	-	no_errors	RP11-642P15.1	Clone_based_vega_gene	ENSG00000214198	tier1	-	-	34	0	0.00	32	9	21.95
GRIA2	0	genome.wustl.edu	37	4	158254480	158254480	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	158254480	158254480	A	C	SNP	GRIA2	ENST00000264426	human	ensembl	74_37	+1	known	missense	c.1130	p.E377A	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_Iontro_glu_rcpt,pfam_ANF_lig-bd_rcpt,pfam_Glu_rcpt_Glu/Gly-bd,pfam_SBP_bac_3,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIA2	HGNC	ENSG00000120251	tier1	-	-	98	0	0.00	47	28	37.33
HGD	0	genome.wustl.edu	37	3	120365861	120365861	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	120365861	120365861	C	T	SNP	HGD	ENST00000283871	human	ensembl	74_37	-1	known	missense	c.508	p.G170S	1.000	pfam_Homogentis_dOase,superfamily_RmlC_Cupin,tigrfam_Homogentis_dOase	pfam_Homogentis_dOase,superfamily_RmlC_Cupin,tigrfam_Homogentis_dOase	-	no_errors	HGD	HGNC	ENSG00000113924	tier1	-	-	38	0	0.00	56	20	26.32
HK3	0	genome.wustl.edu	37	5	176308099	176308099	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	176308099	176308099	C	T	SNP	HK3	ENST00000292432	human	ensembl	74_37	-1	known	missense	c.2747	p.R916H	1.000	pfam_Hexokinase_C	pfam_Hexokinase_C,pfam_Hexokinase_N,prints_Hexokinase	-	no_errors	HK3	HGNC	ENSG00000160883	tier1	-	-	48	0	0.00	22	30	57.69
HMGXB3	0	genome.wustl.edu	37	5	149389760	149389760	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	149389760	149389760	C	T	SNP	HMGXB3	ENST00000502717	human	ensembl	74_37	+1	known	silent	c.399	p.I133	1.000	NULL	pfam_HMG_box_dom,superfamily_HMG_box_dom,smart_HMG_box_dom,pfscan_HMG_box_dom	-	no_errors	HMGXB3	HGNC	ENSG00000113716	tier1	-	-	44	0	0.00	51	4	7.27
HNRNPR	0	genome.wustl.edu	37	1	23636857	23636857	+	RNA	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	23636857	23636857	A	T	SNP	HNRNPR	ENST00000476660	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	HNRNPR	HGNC	ENSG00000125944	tier1	-	-	37	0	0.00	24	15	38.46
HOXD12	0	genome.wustl.edu	37	2	176964615	176964615	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	176964615	176964615	T	C	SNP	HOXD12	ENST00000406506	human	ensembl	74_37	+1	known	missense	c.86	p.L29P	1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa	-	no_errors	HOXD12	HGNC	ENSG00000170178	tier1	-	-	27	0	0.00	10	3	23.08
IL22RA1	0	genome.wustl.edu	37	1	24460793	24460793	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	24460793	24460793	G	A	SNP	IL22RA1	ENST00000270800	human	ensembl	74_37	-1	novel	missense	c.439	p.R147C	0.000	pfam_Interferon_alpha/beta_rcpt_bsu	pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL22RA1	HGNC	ENSG00000142677	tier1	-	-	49	0	0.00	37	21	36.21
ILK	0	genome.wustl.edu	37	11	6631755	6631755	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	6631755	6631755	C	T	SNP	ILK	ENST00000299421	human	ensembl	74_37	+1	known	silent	c.1272	p.L424	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Integrin-linked_kinase,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ankyrin_rpt,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Integrin-linked_kinase,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	ILK	HGNC	ENSG00000166333	tier1	-	-	45	0	0.00	51	15	22.73
INPP5K	0	genome.wustl.edu	37	17	1399635	1399635	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	1399635	1399635	G	T	SNP	INPP5K	ENST00000421807	human	ensembl	74_37	-1	known	missense	c.1163	p.S388Y	0.995	NULL	pfam_Endo/exonuclease/phosphatase,superfamily_Endo/exonuclease/phosphatase,smart_IPPc	-	no_errors	INPP5K	HGNC	ENSG00000132376	tier1	-	-	64	0	0.00	62	4	6.06
IRS4	0	genome.wustl.edu	37	X	107977530	107977530	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	107977530	107977530	G	A	SNP	IRS4	ENST00000372129	human	ensembl	74_37	-1	known	missense	c.2045	p.A682V	0.969	NULL	pfam_Insln_rcpt_S1,smart_Pleckstrin_homology,smart_Insln_rcpt_S1,pfscan_Pleckstrin_homology,pfscan_Insln_rcpt_S1,prints_Insln_rcpt_S1	-	no_errors	IRS4	HGNC	ENSG00000133124	tier1	-	-	51	0	0.00	52	4	7.14
ITGB4	0	genome.wustl.edu	37	17	73726332	73726332	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	73726332	73726332	G	C	SNP	ITGB4	ENST00000200181	human	ensembl	74_37	+1	known	missense	c.749	p.G250A	1.000	pirsf_Integrin_bsu-4,pfam_Integrin_bsu_N,smart_Integrin_bsu_N,prints_Integrin_bsu	pirsf_Integrin_bsu-4,pfam_Integrin_bsu_N,pfam_Fibronectin_type3,pfam_Calx_beta,pfam_Integrin_bsu_tail,pfam_EGF_extracell,superfamily_Fibronectin_type3,superfamily_Integrin_bsu_tail,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,smart_Calx_beta,smart_Fibronectin_type3,prints_Integrin_bsu,pfscan_Fibronectin_type3	-	no_errors	ITGB4	HGNC	ENSG00000132470	tier1	-	-	63	0	0.00	78	12	13.33
KCNA4	0	genome.wustl.edu	37	11	30034735	30034735	+	RNA	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	30034735	30034735	G	A	SNP	KCNA4	ENST00000526518	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.002	-	-	-	no_errors	KCNA4	HGNC	ENSG00000182255	tier1	-	-	75	0	0.00	64	4	5.88
KCNH7	0	genome.wustl.edu	37	2	163302673	163302673	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	163302673	163302673	A	G	SNP	KCNH7	ENST00000332142	human	ensembl	74_37	-1	known	missense	c.1409	p.F470S	1.000	pfam_Ion_trans_dom,prints_K_chnl_volt-dep_EAG/ELK/ERG	pfam_Ion_trans_dom,pfam_cNMP-bd_dom,pfam_2pore_dom_K_chnl_dom,pfam_PAS_fold_3,superfamily_cNMP-bd-like,superfamily_PAS,smart_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ERG,pfscan_cNMP-bd_dom,tigrfam_PAS	-	no_errors	KCNH7	HGNC	ENSG00000184611				28	0	0.00	30	2	6.25
KIAA0319	0	genome.wustl.edu	37	6	24588968	24588968	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	6	24588968	24588968	T	C	SNP	KIAA0319	ENST00000378214	human	ensembl	74_37	-1	known	missense	c.847	p.S283G	0.087	NULL	pfam_PKD/REJ-like,superfamily_PKD_dom,smart_MANSC_N,smart_Fibronectin_type3,smart_PKD/Chitinase_dom,pfscan_MANSC,pfscan_PKD_dom	-	no_errors	KIAA0319	HGNC	ENSG00000137261	tier1	-	-	40	0	0.00	46	29	38.67
KIAA1731	0	genome.wustl.edu	37	11	93416746	93416746	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	93416746	93416746	G	C	SNP	KIAA1731	ENST00000411936	human	ensembl	74_37	+1	known	missense	c.787	p.E263Q	1.000	NULL	NULL	-	no_errors	KIAA1731	HGNC	ENSG00000166004	tier1	-	-	33	0	0.00	34	9	20.93
KIRREL	0	genome.wustl.edu	37	1	158063493	158063493	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	158063493	158063493	C	T	SNP	KIRREL	ENST00000368173	human	ensembl	74_37	+1	known	missense	c.1708	p.R570W	1.000	NULL	pfam_Ig_I-set,pfam_Ig_V-set,pfam_Immunoglobulin,pfam_CD80_C2-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	KIRREL	HGNC	ENSG00000183853	tier1	-	-	36	0	0.00	31	7	18.42
KLC1	0	genome.wustl.edu	37	14	104123994	104123994	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	104123994	104123994	G	A	SNP	KLC1	ENST00000334553	human	ensembl	74_37	+1	known	missense	c.373	p.A125T	1.000	pfam_Rabaptin_Rab5-bd_dom,prints_Kinesin_light	pfam_Rabaptin_Rab5-bd_dom,pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Kinesin_light	-	no_errors	KLC1	HGNC	ENSG00000126214	tier1	-	-	54	0	0.00	54	4	6.90
KLHDC7A	0	genome.wustl.edu	37	1	18809629	18809629	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	18809629	18809629	C	T	SNP	KLHDC7A	ENST00000400664	human	ensembl	74_37	+1	known	silent	c.2154	p.C718	0.998	NULL	pfam_Kelch_1,smart_Kelch_1	-	no_errors	KLHDC7A	HGNC	ENSG00000179023				45	0	0.00	51	3	5.56
KMT2C	0	genome.wustl.edu	37	7	151962134	151962134	+	Nonsense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	151962134	151962134	G	T	SNP	KMT2C	ENST00000355193	human	ensembl	74_37	-1	known	nonsense	c.1173	p.C391*	1.000	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_Znf_RING,pfscan_Znf_PHD-finger	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2C	HGNC	ENSG00000055609	tier1	rs146238849	-	145	0	0.00	117	9	7.14
KMT2C	0	genome.wustl.edu	37	7	151962168	151962168	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	151962168	151962168	C	A	SNP	KMT2C	ENST00000355193	human	ensembl	74_37	-1	known	missense	c.1139	p.R380L	1.000	superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_Znf_RING,pfscan_Znf_PHD-finger,pfscan_Znf_RING	pfam_Znf_PHD-finger,pfam_SET_dom,pfam_FYrich_C,pfam_FYrich_N,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Znf_RING,smart_HMG_box_dom,smart_FYrich_N,smart_FYrich_C,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_Znf_DHHC_palmitoyltrfase,pfscan_Znf_PHD-finger,pfscan_Znf_RING	-	no_errors	KMT2C	HGNC	ENSG00000055609	tier1	rs138908625	-	183	0	0.00	169	16	8.65
KNDC1	0	genome.wustl.edu	37	10	135015007	135015007	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	135015007	135015007	A	G	SNP	KNDC1	ENST00000368572	human	ensembl	74_37	+1	known	missense	c.2998	p.K1000E	0.951	NULL	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,superfamily_Kinase-like_dom,smart_KIND,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	KNDC1	HGNC	ENSG00000171798	tier1	-	-	51	0	0.00	55	4	6.78
LIFR	0	genome.wustl.edu	37	5	38490352	38490352	+	Nonsense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	38490352	38490352	C	A	SNP	LIFR	ENST00000263409	human	ensembl	74_37	-1	known	nonsense	c.2107	p.G703*	1.000	superfamily_Fibronectin_type3	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	LIFR	HGNC	ENSG00000113594	tier1	-	-	89	0	0.00	143	15	9.49
LINC00612	0	genome.wustl.edu	37	12	9208308	9208308	+	RNA	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	9208308	9208308	A	G	SNP	LINC00612	ENST00000538094	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	LINC00612	HGNC	ENSG00000214851	tier1	-	-	58	0	0.00	31	28	47.46
LLGL1	0	genome.wustl.edu	37	17	18137986	18137986	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	18137986	18137986	A	G	SNP	LLGL1	ENST00000316843	human	ensembl	74_37	+1	known	missense	c.874	p.N292D	1.000	pfam_LLGL2,superfamily_WD40_repeat_dom	pfam_LLGL2,pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,prints_Lethal2_giant	-	no_errors	LLGL1	HGNC	ENSG00000131899	tier1	-	-	74	0	0.00	61	25	29.07
LMTK3	0	genome.wustl.edu	37	19	49002994	49002994	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	49002994	49002994	C	T	SNP	LMTK3	ENST00000270238	human	ensembl	74_37	-1	known	silent	c.1419	p.P473	0.935	smart_Ser/Thr_dual-sp_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	LMTK3	HGNC	ENSG00000142235				37	0	0.00	42	3	6.67
LOC100128317	0	genome.wustl.edu	37	7	81218218	81218218	+	RNA	SNP	A	A	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	81218218	81218218	A	C	SNP	LOC100128317	ENST00000413944	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.787	-	-	-	no_errors	AC010091.1	Clone_based_vega_gene	ENSG00000233491	tier1	-	-	38	0	0.00	47	10	17.54
LOC101927795	0	genome.wustl.edu	37	2	201676577	201676577	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	201676577	201676577	C	T	SNP	LOC101927795	ENST00000447972	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.998	-	-	-	no_errors	AC007163.6	Clone_based_vega_gene	ENSG00000230408	tier1	-	-	59	0	0.00	54	10	15.62
LOC101930657	0	genome.wustl.edu	37	1	745347	745347	+	RNA	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	745347	745347	T	C	SNP	LOC101930657	ENST00000412115	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	RP11-206L10.9	Clone_based_vega_gene	ENSG00000237491	tier1	-	-	25	0	0.00	29	9	23.68
LOC440905	0	genome.wustl.edu	37	2	130808123	130808124	+	RNA	INS	-	-	CT			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	130808123	130808124	-	CT	INS	LOC440905	ENST00000325390	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.180:0.170	-	-	-	no_errors	AC018865.8	Clone_based_vega_gene	ENSG00000180178	tier1			12	0	0.00	5	2	28.57
LRRIQ1	0	genome.wustl.edu	37	12	85492759	85492759	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	85492759	85492759	A	T	SNP	LRRIQ1	ENST00000393217	human	ensembl	74_37	+1	known	missense	c.3196	p.I1066F	0.000	NULL	pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,smart_IQ_motif_EF-hand-BS,smart_Leu-rich_rpt_typical-subtyp,pfscan_IQ_motif_EF-hand-BS	-	no_errors	LRRIQ1	HGNC	ENSG00000133640	tier1	-	-	34	0	0.00	54	8	12.90
LTBP1	0	genome.wustl.edu	37	2	33413734	33413734	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	33413734	33413734	C	A	SNP	LTBP1	ENST00000354476	human	ensembl	74_37	+1	known	missense	c.1517	p.P506Q	0.971	NULL	pfam_EGF-like_Ca-bd_dom,pfam_TB_dom,pfam_EG-like_dom,superfamily_TB_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	LTBP1	HGNC	ENSG00000049323	tier1	-	-	45	0	0.00	31	19	38.00
MALAT1	0	genome.wustl.edu	37	11	65271488	65271488	+	RNA	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	65271488	65271488	G	C	SNP	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1	-	-	31	0	0.00	15	12	44.44
MASP1	0	genome.wustl.edu	37	3	186953887	186953887	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	186953887	186953887	G	T	SNP	MASP1	ENST00000296280	human	ensembl	74_37	-1	known	missense	c.1772	p.A591D	1.000	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_CUB_dom,pfam_Sushi_SCR_CCP,pfam_EGF-like_Ca-bd_dom,superfamily_Trypsin-like_Pept_dom,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_EGF-like_Ca-bd_dom,smart_Sushi_SCR_CCP,smart_Peptidase_S1,prints_Peptidase_S1A,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP,pfscan_Peptidase_S1	-	no_errors	MASP1	HGNC	ENSG00000127241	tier1	-	-	21	0	0.00	22	8	26.67
MT-RNR2	0	genome.wustl.edu	37	MT	2928	2928	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	MT	2928	2928	C	T	SNP	MT-RNR2	ENST00000387347	human	ensembl	74_37	+1	known	rna	NULL	NULL	NULL	-	-	-	no_errors	MT-RNR2	HGNC	ENSG00000210082	tier1	-	-	119	0	0.00	37	180	82.95
MTIF2	0	genome.wustl.edu	37	2	55490859	55490859	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	55490859	55490859	C	T	SNP	MTIF2	ENST00000263629	human	ensembl	74_37	-1	known	missense	c.136	p.A46T	0.004	NULL	pfam_EF_GTP-bd_dom,pfam_TIF_IF2_dom3,pfam_Transl_elong_EFTu/EF1A_2,pfam_MIRO-like,pfam_GTP_binding_domain,pfam_Small_GTPase,pfam_SRP_receptor_beta_su,superfamily_P-loop_NTPase,superfamily_TIF_IF2_dom3,superfamily_Transl_B-barrel,tigrfam_Small_GTP-bd_dom	-	no_errors	MTIF2	HGNC	ENSG00000085760	tier1	-	-	51	0	0.00	54	4	6.90
MUC12	0	genome.wustl.edu	37	7	100644340	100644340	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	100644340	100644340	G	A	SNP	MUC12	ENST00000536621	human	ensembl	74_37	+1	known	missense	c.10496	p.G3499D	0.001	NULL	pfam_SEA_dom	-	no_errors	MUC12	HGNC	ENSG00000205277	tier1	-	-	107	0	0.00	85	19	18.27
MUC19	0	genome.wustl.edu	37	12	40919410	40919410	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	40919410	40919410	C	T	SNP	MUC19	ENST00000474954	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MUC19	HGNC	ENSG00000205592	tier1	-	-	86	0	0.00	59	44	41.90
MYBPC3	0	genome.wustl.edu	37	11	47362785	47362785	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	47362785	47362785	G	A	SNP	MYBPC3	ENST00000399249	human	ensembl	74_37	-1	known	silent	c.1801	p.L601	1.000	pfam_Ig_I-set,smart_Ig_sub	pfam_Ig_I-set,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	MYBPC3	HGNC	ENSG00000134571	tier1	-	-	37	0	0.00	25	10	28.57
MYT1	0	genome.wustl.edu	37	20	62871250	62871250	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	62871250	62871250	G	A	SNP	MYT1	ENST00000536311	human	ensembl	74_37	+1	known	silent	c.3312	p.P1104	0.018	NULL	pfam_Myelin_TF,pfam_Znf_C2HC	-	no_errors	MYT1	HGNC	ENSG00000196132	tier1	rs149774713	-	68	0	0.00	53	6	10.17
NAV3	0	genome.wustl.edu	37	12	78392116	78392116	+	Splice_Site	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	78392116	78392116	G	T	SNP	NAV3	ENST00000397909	human	ensembl	74_37	+1	known	splice_site	c.741-1	e7-1	1.000	-	-	-	no_errors	NAV3	HGNC	ENSG00000067798	tier1	-	-	27	0	0.00	19	14	42.42
NCL	0	genome.wustl.edu	37	2	232320317	232320317	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	232320317	232320317	G	A	SNP	NCL	ENST00000322723	human	ensembl	74_37	-1	known	silent	c.1851	p.F617	1.000	pfam_RRM_dom,smart_RRM_dom_euk,smart_RRM_dom,pfscan_RRM_dom	pfam_RRM_dom,smart_RRM_dom,smart_RRM_dom_euk,pfscan_RRM_dom	-	no_errors	NCL	HGNC	ENSG00000115053				20	0	0.00	22	2	8.33
NCOA6	0	genome.wustl.edu	37	20	33330742	33330742	+	Silent	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	33330742	33330742	T	C	SNP	NCOA6	ENST00000359003	human	ensembl	74_37	-1	known	silent	c.3318	p.G1106	1.000	NULL	NULL	-	no_errors	NCOA6	HGNC	ENSG00000198646	tier1	-	-	50	0	0.00	63	4	5.97
NDST1	0	genome.wustl.edu	37	5	149900924	149900924	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	149900924	149900924	C	T	SNP	NDST1	ENST00000261797	human	ensembl	74_37	+1	known	silent	c.108	p.Y36	1.000	pfam_Heparan_SO4_deacetylase	pfam_Heparan_SO4_deacetylase,pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	NDST1	HGNC	ENSG00000070614	tier1	-	-	51	0	0.00	39	17	30.36
NPM1	0	genome.wustl.edu	37	5	170817096	170817096	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	170817096	170817096	G	C	SNP	NPM1	ENST00000296930	human	ensembl	74_37	+1	known	missense	c.100	p.D34H	1.000	superfamily_Nucleoplasmin_core_dom	superfamily_Nucleoplasmin_core_dom	-	no_errors	NPM1	HGNC	ENSG00000181163	tier1	-	-	82	0	0.00	41	10	19.23
NRXN3	0	genome.wustl.edu	37	14	80158529	80158529	+	Silent	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	80158529	80158529	T	C	SNP	NRXN3	ENST00000554738	human	ensembl	74_37	+1	known	silent	c.3597	p.N1199	1.000	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	NRXN3	HGNC	ENSG00000021645	tier1	-	-	39	0	0.00	11	11	50.00
NUDT16	0	genome.wustl.edu	37	3	131102146	131102146	+	Silent	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	131102146	131102146	T	C	SNP	NUDT16	ENST00000521288	human	ensembl	74_37	+1	known	silent	c.549	p.S183	0.378	superfamily_NUDIX_hydrolase_dom-like	pfam_NUDIX_hydrolase_dom,superfamily_NUDIX_hydrolase_dom-like	-	no_errors	NUDT16	HGNC	ENSG00000198585	tier1	-	-	40	0	0.00	58	4	6.45
NUPR1	0	genome.wustl.edu	37	16	28549406	28549406	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	16	28549406	28549406	C	T	SNP	NUPR1	ENST00000324873	human	ensembl	74_37	-1	known	silent	c.183	p.G61	1.000	pfam_Nuclear_phosphoprot_p8_DNA-bd	pfam_Nuclear_phosphoprot_p8_DNA-bd	-	no_errors	NUPR1	HGNC	ENSG00000176046	tier1	-	-	31	0	0.00	36	5	12.20
OR5AR1	0	genome.wustl.edu	37	11	56431333	56431333	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	56431333	56431333	C	T	SNP	OR5AR1	ENST00000302969	human	ensembl	74_37	+1	known	missense	c.172	p.P58S	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5AR1	HGNC	ENSG00000172459	tier1	-	-	67	0	0.00	54	16	22.86
OR5H2	0	genome.wustl.edu	37	3	98002101	98002101	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	98002101	98002101	G	A	SNP	OR5H2	ENST00000355273	human	ensembl	74_37	+1	known	missense	c.370	p.A124T	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5H2	HGNC	ENSG00000197938	tier1	-	-	48	0	0.00	57	4	6.56
OR6B2	0	genome.wustl.edu	37	2	240968939	240968939	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	240968939	240968939	T	C	SNP	OR6B2	ENST00000402971	human	ensembl	74_37	-1	known	missense	c.908	p.K303R	0.018	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6B2	HGNC	ENSG00000182083	tier1	-	-	61	0	0.00	56	4	6.67
OR8G5	0	genome.wustl.edu	37	11	124135465	124135465	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	124135465	124135465	C	T	SNP	OR8G5	ENST00000524943	human	ensembl	74_37	+1	known	missense	c.743	p.T248I	0.002	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8G5	HGNC	ENSG00000255298	tier1	-	-	98	0	0.00	97	34	25.95
PARP4	0	genome.wustl.edu	37	13	25016071	25016072	+	Frame_Shift_Del	DEL	TT	TT	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	TT	TT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	25016071	25016072	TT	-	DEL	PARP4	ENST00000381989	human	ensembl	74_37	-1	known	frame_shift_del	c.3579_3578	p.K1193fs	0.338:0.838	NULL	pfam_Poly(ADP-ribose)pol_cat_dom,pfam_VIT,pfam_VWF_A,pfam_BRCT_dom,superfamily_Poly(ADP-ribose)pol_reg_dom,superfamily_BRCT_dom,smart_BRCT_dom,smart_VIT,smart_VWF_A,pfscan_BRCT_dom,pfscan_VWF_A,pfscan_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_reg_dom	-	no_errors	PARP4	HGNC	ENSG00000102699	tier1			42	0	0.00	31	5	13.89
PCDHGB1	0	genome.wustl.edu	37	5	140729955	140729955	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	140729955	140729955	C	T	SNP	PCDHGB1	ENST00000523390	human	ensembl	74_37	+1	known	missense	c.128	p.S43L	0.998	pfam_Cadherin_N,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHGB1	HGNC	ENSG00000254221	tier1	-	-	76	0	0.00	34	15	30.61
PHF19	0	genome.wustl.edu	37	9	123625142	123625142	+	RNA	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	9	123625142	123625142	C	T	SNP	PHF19	ENST00000467266	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PHF19	HGNC	ENSG00000119403	tier1	-	-	12	0	0.00	14	7	33.33
PHKA2	0	genome.wustl.edu	37	X	18954191	18954191	+	Nonsense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	18954191	18954191	G	C	SNP	PHKA2	ENST00000379942	human	ensembl	74_37	-1	known	nonsense	c.1119	p.Y373*	0.986	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	pfam_Glyco_hydro_15,superfamily_6-hairpin_glycosidase-like	-	no_errors	PHKA2	HGNC	ENSG00000044446	tier1	-	-	18	0	0.00	8	6	42.86
PIGO	0	genome.wustl.edu	37	9	35092618	35092618	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	9	35092618	35092618	C	T	SNP	PIGO	ENST00000341666	human	ensembl	74_37	-1	known	silent	c.1266	p.P422	0.884	NULL	pfam_Phosphodiest/P_Trfase,pfam_Metalloenzyme,pfam_Sulfatase,superfamily_Alkaline_phosphatase_core	-	no_errors	PIGO	HGNC	ENSG00000165282				27	0	0.00	19	2	9.52
PIKFYVE	0	genome.wustl.edu	37	2	209150489	209150489	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	209150489	209150489	T	C	SNP	PIKFYVE	ENST00000264380	human	ensembl	74_37	+1	known	missense	c.653	p.L218S	1.000	superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,pfscan_Znf_FYVE-rel	pfam_PInositol-4-P-5-kinase_core,pfam_Cpn60/TCP-1,pfam_DEP_dom,pfam_Znf_FYVE,superfamily_GroEL-like_apical_dom,superfamily_Znf_FYVE_PHD,smart_Znf_FYVE,smart_DEP_dom,smart_PInositol-4P-5-kinase_core_sub,pfscan_DEP_dom,pfscan_Znf_FYVE-rel	-	no_errors	PIKFYVE	HGNC	ENSG00000115020	tier1	-	-	40	0	0.00	52	13	20.00
PKD1L2	0	genome.wustl.edu	37	16	81219257	81219257	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	16	81219257	81219257	G	A	SNP	PKD1L2	ENST00000337114	human	ensembl	74_37	-1	known	missense	c.1837	p.R613C	0.000	pfam_PKD/REJ-like,pfscan_REJ-like	pfam_Lectin_gal-bd_dom,pfam_C-type_lectin,pfam_PKD/REJ-like,superfamily_C-type_lectin_fold,superfamily_Coatomer/clathrin_app_Ig-like,superfamily_PKD_dom,smart_C-type_lectin,pfscan_C-type_lectin,pfscan_Lectin_gal-bd_dom,pfscan_REJ-like	-	no_errors	PKD1L2	HGNC	ENSG00000166473	tier1	rs199529211	-	73	0	0.00	47	42	47.19
PLXNA2	0	genome.wustl.edu	37	1	208218548	208218548	+	Frame_Shift_Del	DEL	T	T	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	208218548	208218548	T	-	DEL	PLXNA2	ENST00000367033	human	ensembl	74_37	-1	known	frame_shift_del	c.3503	p.N1168fs	1.000	pfam_IPT,superfamily_Ig_E-set,smart_IPT	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_Semap_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLXNA2	HGNC	ENSG00000076356	tier1			31	0	0.00	25	3	10.71
POLD1	0	genome.wustl.edu	37	19	50905960	50905960	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	50905960	50905960	G	C	SNP	POLD1	ENST00000440232	human	ensembl	74_37	+1	known	missense	c.932	p.R311P	0.992	pfam_DNA-dir_DNA_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_DNA-dir_DNA_pol_B	pfam_DNA-dir_DNA_pol_B_multi_dom,pfam_DNA-dir_DNA_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_DNA-dir_DNA_pol_B,prints_DNA-dir_DNA_pol_B,tigrfam_DNA-dir_DNA_pol_B_pol2	-	no_errors	POLD1	HGNC	ENSG00000062822	tier1	-	-	39	0	0.00	38	7	15.56
POU4F2	0	genome.wustl.edu	37	4	147561259	147561261	+	In_Frame_Del	DEL	CAC	CAC	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	CAC	CAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	147561259	147561261	CAC	-	DEL	POU4F2	ENST00000281321	human	ensembl	74_37	+1	known	in_frame_del	c.529_531	p.H180in_frame_del	1.000:1.000:0.999	NULL	pfam_POU_specific,pfam_Homeobox_dom,superfamily_Lambda_DNA-bd_dom,superfamily_Homeodomain-like,smart_POU_specific,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_POU_specific,prints_POU	-	no_errors	POU4F2	HGNC	ENSG00000151615	tier1			52	0	0.00	29	2	6.45
PRAMEF5	0	genome.wustl.edu	37	1	13365855	13365855	+	Missense_Mutation	SNP	T	T	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	13365855	13365855	T	G	SNP	PRAMEF5	ENST00000376168	human	ensembl	74_37	+1	known	missense	c.299	p.L100R	0.003	NULL	NULL	-	no_errors	PRAMEF5	HGNC	ENSG00000204502				130	0	0.00	68	7	9.33
PRAMEF6	0	genome.wustl.edu	37	1	13001384	13001384	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	13001384	13001384	A	C	SNP	PRAMEF6	ENST00000355096	human	ensembl	74_37	-1	known	missense	c.299	p.L100R	0.007	NULL	NULL	-	no_errors	PRAMEF6	HGNC	ENSG00000232423				214	0	0.00	167	16	8.70
PROS1	0	genome.wustl.edu	37	3	93593094	93593094	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	93593094	93593094	A	T	SNP	PROS1	ENST00000394236	human	ensembl	74_37	-1	known	missense	c.2026	p.S676T	0.065	NULL	pfam_Laminin_G,pfam_EGF-like_Ca-bd_dom,pfam_GLA_domain,pfam_EG-like_dom,superfamily_ConA-like_lec_gl_sf,superfamily_GLA_domain,smart_GLA_domain,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_GLA_domain,pfscan_Laminin_G,prints_GLA_domain	-	no_errors	PROS1	HGNC	ENSG00000184500	tier1	-	-	80	0	0.00	109	22	16.79
PTCHD3	0	genome.wustl.edu	37	10	27702567	27702567	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	27702567	27702567	C	T	SNP	PTCHD3	ENST00000438700	human	ensembl	74_37	-1	known	missense	c.613	p.E205K	0.004	pfam_Patched	pfam_Patched,pfscan_SSD	-	no_errors	PTCHD3	HGNC	ENSG00000182077				20	0	0.00	34	2	5.56
RAD17	0	genome.wustl.edu	37	5	68692375	68692376	+	Splice_Site	INS	-	-	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	68692375	68692376	-	A	INS	RAD17	ENST00000380774	human	ensembl	74_37	+1	known	splice_site_ins	c.1605+2_1605+1	e13+2	1.000:0.992	-	-	-	no_errors	RAD17	HGNC	ENSG00000152942	tier1			17	0	0.00	16	5	23.81
RANBP1	0	genome.wustl.edu	37	22	20109826	20109826	+	Silent	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	22	20109826	20109826	C	G	SNP	RANBP1	ENST00000331821	human	ensembl	74_37	+1	known	silent	c.192	p.L64	0.833	pfam_Ran_bind_dom,smart_Ran_bind_dom,pfscan_Ran_bind_dom	pfam_Ran_bind_dom,smart_Ran_bind_dom,pfscan_Ran_bind_dom	-	no_errors	RANBP1	HGNC	ENSG00000099901	tier1	-	-	27	0	0.00	22	12	34.29
RAPGEF2	0	genome.wustl.edu	37	4	160189325	160189325	+	Silent	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	160189325	160189325	C	A	SNP	RAPGEF2	ENST00000264431	human	ensembl	74_37	+1	known	silent	c.18	p.I6	0.999	NULL	pfam_RasGRF_CDC25,pfam_Ras-assoc,pfam_Ras-like_Gua-exchang_fac_N,pfam_PDZ,pfam_cNMP-bd_dom,superfamily_Ras_GEF_dom,superfamily_PDZ,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_Ras-like_Gua-exchang_fac_N,smart_PDZ,smart_Ras-assoc,smart_RasGRF_CDC25,pfscan_cNMP-bd_dom,pfscan_PDZ,pfscan_Ras-assoc,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	RAPGEF2	HGNC	ENSG00000109756	tier1	-	-	49	0	0.00	63	5	7.35
RASL11B	0	genome.wustl.edu	37	4	53729447	53729447	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	53729447	53729447	G	A	SNP	RASL11B	ENST00000248706	human	ensembl	74_37	+1	known	missense	c.155	p.R52Q	0.998	pfam_Small_GTPase,pfam_MIRO-like,pfam_Fe2_transport_prot_B_N,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Fe2_transport_prot_B_N,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	-	no_errors	RASL11B	HGNC	ENSG00000128045	tier1	-	-	69	0	0.00	55	4	6.78
RBM48	0	genome.wustl.edu	37	7	92163945	92163945	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	92163945	92163945	G	T	SNP	RBM48	ENST00000265732	human	ensembl	74_37	+1	known	missense	c.678	p.K226N	0.000	NULL	NULL	-	no_errors	RBM48	HGNC	ENSG00000127993				51	0	0.00	56	3	5.08
RGS2	0	genome.wustl.edu	37	1	192778269	192778269	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	192778269	192778269	G	A	SNP	RGS2	ENST00000235382	human	ensembl	74_37	+1	known	missense	c.68	p.G23D	0.061	NULL	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS2	HGNC	ENSG00000116741				71	0	0.00	66	4	5.71
RGSL1	0	genome.wustl.edu	37	1	182443066	182443066	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	182443066	182443066	G	T	SNP	RGSL1	ENST00000294854	human	ensembl	74_37	+1	known	missense	c.820	p.A274S	0.000	NULL	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam	-	no_errors	RGSL1	HGNC	ENSG00000121446	tier1	-	-	29	0	0.00	24	12	33.33
RNF167	0	genome.wustl.edu	37	17	4846522	4846522	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	4846522	4846522	C	T	SNP	RNF167	ENST00000262482	human	ensembl	74_37	+1	known	silent	c.519	p.Y173	1.000	NULL	pfam_Protease-assoc_domain,pfam_Znf_C3HC4_RING-type,smart_Znf_RING-CH,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF167	HGNC	ENSG00000108523	tier1	-	-	70	0	0.00	73	4	5.19
RSPH10B	0	genome.wustl.edu	37	7	6000459	6000459	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	6000459	6000459	C	T	SNP	RSPH10B	ENST00000337579	human	ensembl	74_37	-1	known	missense	c.436	p.V146M	0.000	pfam_MORN,smart_MORN	pfam_MORN,smart_MORN	-	no_errors	RSPH10B	HGNC	ENSG00000155026	tier1	-	-	48	0	0.00	49	31	38.75
S1PR1	0	genome.wustl.edu	37	1	101704654	101704654	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	101704654	101704654	C	T	SNP	S1PR1	ENST00000305352	human	ensembl	74_37	+1	known	silent	c.114	p.S38	0.021	prints_EDG1_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_EDG1_rcpt,prints_S1P_rcpt,prints_GPCR_Rhodpsn,prints_Melcrt_ACTH_rcpt	-	no_errors	S1PR1	HGNC	ENSG00000170989	tier1	-	-	61	0	0.00	30	14	31.82
SACS	0	genome.wustl.edu	37	13	23915230	23915230	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	13	23915230	23915230	G	A	SNP	SACS	ENST00000382292	human	ensembl	74_37	-1	known	missense	c.2785	p.R929C	0.995	NULL	pfam_HEPN,pfam_Ubiquitin_dom,superfamily_HATPase_ATP-bd,superfamily_DnaJ_domain,smart_HEPN,pfscan_HEPN,pfscan_DnaJ_domain,pfscan_Ubiquitin_supergroup	-	no_errors	SACS	HGNC	ENSG00000151835	tier1	-	-	39	0	0.00	32	12	27.27
SCAMP4	0	genome.wustl.edu	37	19	1917794	1917794	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	1917794	1917794	G	A	SNP	SCAMP4	ENST00000316097	human	ensembl	74_37	+1	known	missense	c.109	p.V37M	0.992	pfam_SCAMP	pfam_SCAMP	-	no_errors	SCAMP4	HGNC	ENSG00000227500				40	0	0.00	28	2	6.67
SERPINB11	0	genome.wustl.edu	37	18	61377452	61377452	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	18	61377452	61377452	G	A	SNP	SERPINB11	ENST00000538847	human	ensembl	74_37	+1	known	missense	c.25	p.V9I	0.003	pfam_Serpin_dom,superfamily_Serpin_dom	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	-	no_errors	SERPINB11	HGNC	ENSG00000206072	tier1	-	-	61	0	0.00	73	7	8.75
SETD1B	0	genome.wustl.edu	37	12	122257764	122257764	+	Silent	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	122257764	122257764	G	C	SNP	SETD1B	ENST00000267197	human	ensembl	74_37	+1	known	silent	c.3744	p.V1248	0.089	NULL	pfam_COMPASS_Set1_N-SET,pfam_SET_dom,pfam_RRM_dom,smart_RRM_dom,smart_SET_dom,smart_Post-SET_dom,pfscan_SET_dom,pfscan_Post-SET_dom,pfscan_RRM_dom	-	no_errors	SETD1B	HGNC	ENSG00000139718	tier1	-	-	80	0	0.00	47	32	40.51
SLC41A2	0	genome.wustl.edu	37	12	105198776	105198777	+	RNA	INS	-	-	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	105198776	105198777	-	A	INS	SLC41A2	ENST00000549713	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.757:0.849	-	-	-	no_errors	SLC41A2	HGNC	ENSG00000136052	tier1			36	0	0.00	36	4	10.00
SLC8A2	0	genome.wustl.edu	37	19	47960551	47960551	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	47960551	47960551	G	A	SNP	SLC8A2	ENST00000236877	human	ensembl	74_37	-1	known	missense	c.976	p.H326Y	1.000	tigrfam_Na_Ca_Ex	pfam_Calx_beta,pfam_NaCa_Exmemb,smart_Calx_beta,prints_Na_Ca_Ex,tigrfam_Na_Ca_Ex	-	no_errors	SLC8A2	HGNC	ENSG00000118160	tier1	-	-	13	0	0.00	5	10	66.67
SLCO1A2	0	genome.wustl.edu	37	12	21447016	21447016	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	12	21447016	21447016	C	G	SNP	SLCO1A2	ENST00000307378	human	ensembl	74_37	-1	known	missense	c.1300	p.D434H	0.000	pfam_OA_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	pfam_OA_transporter,pfam_MFS,pfam_Kazal_dom,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_OA_transporter	-	no_errors	SLCO1A2	HGNC	ENSG00000084453	tier1	-	-	47	0	0.00	17	18	51.43
SMARCA4	0	genome.wustl.edu	37	19	11152145	11152145	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	11152145	11152145	C	T	SNP	SMARCA4	ENST00000358026	human	ensembl	74_37	+1	known	missense	c.4429	p.R1477W	1.000	superfamily_Bromodomain	pfam_SNF2_N,pfam_Bromodomain,pfam_BRK_domain,pfam_Helicase/SANT-assoc_DNA-bd,pfam_Helicase_C,pfam_Gln-Leu-Gln_QLQ,superfamily_P-loop_NTPase,superfamily_Bromodomain,smart_Gln-Leu-Gln_QLQ,smart_HAS_subgr,smart_BRK_domain,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Bromodomain,prints_Bromodomain,pfscan_Helicase/SANT-assoc_DNA-bd,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Bromodomain	-	no_errors	SMARCA4	HGNC	ENSG00000127616	tier1	-	-	69	0	0.00	35	100	70.92
SRGAP3	0	genome.wustl.edu	37	3	9100060	9100060	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	9100060	9100060	C	A	SNP	SRGAP3	ENST00000383836	human	ensembl	74_37	-1	known	missense	c.898	p.D300Y	1.000	NULL	pfam_RhoGAP_dom,pfam_FCH_dom,pfam_SH3_domain,pfam_SH3_2,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,smart_FCH_dom,smart_RhoGAP_dom,smart_SH3_domain,pfscan_FCH_dom,pfscan_SH3_domain,pfscan_RhoGAP_dom	-	no_errors	SRGAP3	HGNC	ENSG00000196220	tier1	-	-	64	0	0.00	43	27	38.57
SRP54	0	genome.wustl.edu	37	14	35483965	35483965	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	35483965	35483965	A	G	SNP	SRP54	ENST00000216774	human	ensembl	74_37	+1	known	missense	c.902	p.E301G	1.000	superfamily_Signal_recog_particle_SRP54_M,tigrfam_SRP54_euk	pfam_SRP54_GTPase_dom,pfam_Signal_recog_particle_SRP54_M,pfam_Signal_recog_particl_SRP54_hlx,pfam_CobW/HypB/UreG_dom,pfam_CobQ/CobB/MinD/ParA_Nub-bd_dom,superfamily_P-loop_NTPase,superfamily_Signal_recog_particle_SRP54_M,superfamily_Signal_recog_particl_SRP54_hlx,smart_Signal_recog_particl_SRP54_hlx,smart_AAA+_ATPase,smart_SRP54_GTPase_dom,tigrfam_SRP54_euk	-	no_errors	SRP54	HGNC	ENSG00000100883	tier1	-	-	42	0	0.00	24	3	11.11
SRRM2	0	genome.wustl.edu	37	16	2812116	2812116	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	16	2812116	2812116	G	T	SNP	SRRM2	ENST00000301740	human	ensembl	74_37	+1	known	missense	c.1587	p.Q529H	0.986	NULL	pfam_mRNA_splic_Cwf21	-	no_errors	SRRM2	HGNC	ENSG00000167978				46	0	0.00	42	4	8.70
SUN5	0	genome.wustl.edu	37	20	31571644	31571644	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	31571644	31571644	G	T	SNP	SUN5	ENST00000356173	human	ensembl	74_37	-1	known	missense	c.1096	p.P366T	0.451	NULL	pfam_Sad1_UNC_C,superfamily_Galactose-bd-like	-	no_errors	SUN5	HGNC	ENSG00000167098	tier1	-	-	74	0	0.00	89	10	10.10
TACC2	0	genome.wustl.edu	37	10	123987479	123987479	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	10	123987479	123987479	C	T	SNP	TACC2	ENST00000334433	human	ensembl	74_37	+1	known	silent	c.7852	p.L2618	1.000	NULL	pfam_TACC	-	no_errors	TACC2	HGNC	ENSG00000138162				35	0	0.00	35	3	7.89
TANC1	0	genome.wustl.edu	37	2	160086369	160086369	+	Nonsense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	160086369	160086369	C	T	SNP	TANC1	ENST00000263635	human	ensembl	74_37	+1	known	nonsense	c.4432	p.Q1478*	0.569	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,superfamily_P-loop_NTPase,smart_Ankyrin_rpt,smart_TPR_repeat,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Ankyrin_rpt	-	no_errors	TANC1	HGNC	ENSG00000115183				26	0	0.00	19	3	13.64
TBCEL	0	genome.wustl.edu	37	11	120930683	120930683	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	120930683	120930683	C	G	SNP	TBCEL	ENST00000422003	human	ensembl	74_37	+1	known	missense	c.845	p.P282R	1.000	NULL	pfscan_Ubiquitin_supergroup	-	no_errors	TBCEL	HGNC	ENSG00000154114	tier1	-	-	72	0	0.00	65	20	23.53
TBX20	0	genome.wustl.edu	37	7	35284578	35284578	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	35284578	35284578	G	T	SNP	TBX20	ENST00000408931	human	ensembl	74_37	-1	known	missense	c.637	p.L213M	1.000	pfam_TF_T-box,superfamily_p53-like_TF_DNA-bd,smart_TF_T-box,pfscan_TF_T-box	pfam_TF_T-box,superfamily_p53-like_TF_DNA-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box	-	no_errors	TBX20	HGNC	ENSG00000164532	tier1	-	-	83	0	0.00	83	9	9.68
TC2N	0	genome.wustl.edu	37	14	92251624	92251624	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	92251624	92251624	C	T	SNP	TC2N	ENST00000340892	human	ensembl	74_37	-1	known	missense	c.1244	p.G415E	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	TC2N	HGNC	ENSG00000165929	tier1	-	-	56	0	0.00	53	4	7.02
TCF4	0	genome.wustl.edu	37	18	53017598	53017598	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	18	53017598	53017598	G	A	SNP	TCF4	ENST00000398339	human	ensembl	74_37	-1	known	missense	c.847	p.P283S	1.000	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	TCF4	HGNC	ENSG00000196628	tier1	-	-	45	0	0.00	59	4	6.35
TIGD2	0	genome.wustl.edu	37	4	90034819	90034819	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	90034819	90034819	A	-	DEL	TIGD2	ENST00000317005	human	ensembl	74_37	+1	known	frame_shift_del	c.694	p.K233fs	0.931	pfam_DDE_SF_endonuclease_CENPB-like	pfam_DDE_SF_endonuclease_CENPB-like,pfam_HTH_CenpB_DNA-bd_dom,pfam_HTH_Psq,superfamily_Homeodomain-like,smart_HTH_CenpB_DNA-bd_dom,pfscan_HTH_Psq	-	no_errors	TIGD2	HGNC	ENSG00000180346	tier1			43	0	0.00	28	2	6.67
TIGD6	0	genome.wustl.edu	37	5	149375184	149375187	+	Frame_Shift_Del	DEL	GAAT	GAAT	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	GAAT	GAAT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	5	149375184	149375187	GAAT	-	DEL	TIGD6	ENST00000296736	human	ensembl	74_37	-1	known	frame_shift_del	c.728_725	p.H242fs	0.917:0.791:0.794:0.949	pfam_DDE_SF_endonuclease_CENPB-like	pfam_DDE_SF_endonuclease_CENPB-like,pfam_HTH_CenpB_DNA-bd_dom,pfam_HTH_Psq,superfamily_Homeodomain-like,smart_HTH_CenpB_DNA-bd_dom,pfscan_HTH_Psq	-	no_errors	TIGD6	HGNC	ENSG00000164296	tier1			49	0	0.00	49	13	20.97
TMED10	0	genome.wustl.edu	37	14	75601711	75601712	+	Splice_Site	INS	-	-	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	14	75601711	75601712	-	A	INS	TMED10	ENST00000303575	human	ensembl	74_37	-1	known	splice_site_ins	c.539-3_539-2	e5-2	1.000:0.961	-	-	-	no_errors	TMED10	HGNC	ENSG00000170348	tier1			35	0	0.00	32	4	11.11
TMEM132E	0	genome.wustl.edu	37	17	32953491	32953491	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	32953491	32953491	C	T	SNP	TMEM132E	ENST00000321639	human	ensembl	74_37	+1	known	missense	c.413	p.S138L	1.000	NULL	NULL	-	no_errors	TMEM132E	HGNC	ENSG00000181291	tier1	-	-	80	0	0.00	34	32	48.48
TMEM185B	0	genome.wustl.edu	37	2	120980160	120980160	+	Silent	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	120980160	120980160	G	C	SNP	TMEM185B	ENST00000426077	human	ensembl	74_37	-1	known	silent	c.393	p.V131	0.987	pfam_TM_Fragile-X-F-assoc	pfam_TM_Fragile-X-F-assoc	-	no_errors	TMEM185B	HGNC	ENSG00000226479	tier1	-	-	32	0	0.00	26	9	25.71
TMEM200C	0	genome.wustl.edu	37	18	5892004	5892004	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	18	5892004	5892004	G	C	SNP	TMEM200C	ENST00000383490	human	ensembl	74_37	-1	known	missense	c.59	p.P20R	0.958	pfam_DUF2371_TMEM200	pfam_DUF2371_TMEM200	-	no_errors	TMEM200C	HGNC	ENSG00000206432	tier1	-	-	44	0	0.00	51	7	12.07
TOP2B	0	genome.wustl.edu	37	3	25672379	25672379	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	25672379	25672379	C	T	SNP	TOP2B	ENST00000264331	human	ensembl	74_37	-1	known	missense	c.1318	p.A440T	1.000	pfam_Topo_IIA_bsu_dom2,smart_Topo_IIA	pfam_Topo_IIA_A/C,pfam_Topo_IIA_bsu_dom2,pfam_DTHCT,pfam_HATPase_ATP-bd,superfamily_Topo_IIA_like_dom,superfamily_HATPase_ATP-bd,superfamily_Ribosomal_S5_D2-typ_fold,smart_Topo_IIA,smart_Topo_IIA_A/C,prints_TopoII_euk,prints_Topo_IIA,prints_Transcrpt_fac_NFYB/HAP3	-	no_errors	TOP2B	HGNC	ENSG00000077097	tier1	-	-	42	0	0.00	24	27	52.94
TP53	0	genome.wustl.edu	37	17	7577106	7577106	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	17	7577106	7577106	G	C	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.832	p.P278A	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	rs17849781	-	31	0	0.00	21	22	51.16
TRAPPC9	0	genome.wustl.edu	37	8	141461322	141461322	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	8	141461322	141461322	G	A	SNP	TRAPPC9	ENST00000389328	human	ensembl	74_37	-1	known	nonsense	c.445	p.R149*	1.000	NULL	pfam_TRAPP_II_complex_Trs120	-	no_errors	TRAPPC9	HGNC	ENSG00000167632	tier1	-	-	23	0	0.00	27	23	46.00
TRIM26	0	genome.wustl.edu	37	6	30154080	30154082	+	In_Frame_Del	DEL	TCC	TCC	-			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	TCC	TCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	6	30154080	30154082	TCC	-	DEL	TRIM26	ENST00000437089	human	ensembl	74_37	-1	known	in_frame_del	c.1193_1191	p.E400in_frame_del	0.559:0.740:0.761	superfamily_ConA-like_lec_gl_sf,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM26	HGNC	ENSG00000234127	tier1			26	0	0.00	29	2	6.45
TRNT1	0	genome.wustl.edu	37	3	3179029	3179029	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	3179029	3179029	A	G	SNP	TRNT1	ENST00000251607	human	ensembl	74_37	+1	known	missense	c.234	p.I78M	0.999	pfam_PolA_pol_head_dom	pfam_PolA_pol_head_dom	-	no_errors	TRNT1	HGNC	ENSG00000072756				68	0	0.00	51	4	7.27
TRPC1	0	genome.wustl.edu	37	3	142511809	142511809	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	3	142511809	142511809	G	A	SNP	TRPC1	ENST00000476941	human	ensembl	74_37	+1	known	silent	c.1581	p.Q527	1.000	pfam_Ion_trans_dom,tigrfam_TRP_channel	pfam_TRP_dom,pfam_Ion_trans_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,prints_TRPC1_channel,prints_TRPC_channel,tigrfam_TRP_channel	-	no_errors	TRPC1	HGNC	ENSG00000144935	tier1	-	-	41	0	0.00	42	31	42.47
TTN	0	genome.wustl.edu	37	2	179428350	179428350	+	Silent	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	179428350	179428350	G	T	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	silent	c.74805	p.G24935	0.746	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	75	0	0.00	59	24	28.92
TUT1	0	genome.wustl.edu	37	11	62346473	62346473	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	11	62346473	62346473	C	T	SNP	TUT1	ENST00000308436	human	ensembl	74_37	-1	known	silent	c.834	p.S278	0.506	NULL	pfam_PAP_assoc,pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	TUT1	HGNC	ENSG00000149016				65	0	0.00	53	4	7.02
UBIAD1	0	genome.wustl.edu	37	1	11333870	11333870	+	Silent	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	11333870	11333870	G	A	SNP	UBIAD1	ENST00000376810	human	ensembl	74_37	+1	known	silent	c.282	p.V94	1.000	pfam_UbiA_prenyltransferase	pfam_UbiA_prenyltransferase	-	no_errors	UBIAD1	HGNC	ENSG00000120942	tier1	-	-	74	0	0.00	65	5	7.14
ULK4P3	0	genome.wustl.edu	37	15	30406189	30406189	+	RNA	SNP	G	G	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	15	30406189	30406189	G	T	SNP	ULK4P3	ENST00000566138	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.001	-	-	-	no_errors	ULK4P3	HGNC	ENSG00000178081	tier1	-	-	78	0	0.00	55	27	32.93
UNCX	0	genome.wustl.edu	37	7	1273157	1273157	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	1273157	1273157	C	A	SNP	UNCX	ENST00000316333	human	ensembl	74_37	+1	known	missense	c.276	p.D92E	1.000	superfamily_Homeodomain-like	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	UNCX	HGNC	ENSG00000164853	tier1	-	-	101	0	0.00	120	10	7.69
UTP3	0	genome.wustl.edu	37	4	71554761	71554761	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	71554761	71554761	G	A	SNP	UTP3	ENST00000254803	human	ensembl	74_37	+1	known	missense	c.367	p.V123M	0.003	NULL	pfam_Sas10_C_dom,pfam_Sas10/Utp3/C1D	-	no_errors	UTP3	HGNC	ENSG00000132467	tier1	-	-	35	0	0.00	24	4	14.29
WDR65	0	genome.wustl.edu	37	1	43664319	43664320	+	Splice_Site	INS	-	-	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	1	43664319	43664320	-	A	INS	WDR65	ENST00000528956	human	ensembl	74_37	+1	known	splice_site_ins	c.1428+2_1428+1	e7+2	1.000:0.995	-	-	-	no_errors	WDR65	HGNC	ENSG00000243710	tier1			31	0	0.00	65	9	12.16
XKR4	0	genome.wustl.edu	37	8	56436193	56436193	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	8	56436193	56436193	C	T	SNP	XKR4	ENST00000327381	human	ensembl	74_37	+1	known	missense	c.1360	p.R454C	1.000	pfam_Transport_prot_XK	pfam_Transport_prot_XK	-	no_errors	XKR4	HGNC	ENSG00000206579	tier1	-	-	57	0	0.00	53	22	29.33
XRCC2	0	genome.wustl.edu	37	7	152345900	152345900	+	Nonsense_Mutation	SNP	T	T	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	7	152345900	152345900	T	A	SNP	XRCC2	ENST00000359321	human	ensembl	74_37	-1	known	nonsense	c.670	p.R224*	0.996	superfamily_P-loop_NTPase	pfam_DNA_recomb/repair_Rad51_C,superfamily_P-loop_NTPase,pfscan_DNA_recomb_RecA/RadB_ATP-bd	-	no_errors	XRCC2	HGNC	ENSG00000196584	tier1	-	-	55	0	0.00	58	4	6.45
ZBTB7A	0	genome.wustl.edu	37	19	4048040	4048040	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	4048040	4048040	C	T	SNP	ZBTB7A	ENST00000322357	human	ensembl	74_37	-1	known	missense	c.1465	p.G489S	1.000	pfscan_Znf_C2H2	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB7A	HGNC	ENSG00000178951				30	0	0.00	21	3	12.50
ZDBF2	0	genome.wustl.edu	37	2	207174427	207174428	+	Frame_Shift_Ins	INS	-	-	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	2	207174427	207174428	-	A	INS	ZDBF2	ENST00000374423	human	ensembl	74_37	+1	known	frame_shift_ins	c.5175_5176	p.R1728fs	0.000:0.000	NULL	pfam_Znf_DBF,smart_Znf_DBF	-	no_errors	ZDBF2	HGNC	ENSG00000204186	tier1			29	0	0.00	27	2	6.90
ZFP14	0	genome.wustl.edu	37	19	36831606	36831606	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	36831606	36831606	C	T	SNP	ZFP14	ENST00000270001	human	ensembl	74_37	-1	known	silent	c.1122	p.G374	1.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZFP14	HGNC	ENSG00000142065	tier1	-	-	57	0	0.00	44	4	8.33
ZFP64	0	genome.wustl.edu	37	20	50701305	50701305	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	20	50701305	50701305	G	A	SNP	ZFP64	ENST00000361387	human	ensembl	74_37	-1	known	nonsense	c.1729	p.Q577*	0.994	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZFP64	HGNC	ENSG00000020256	tier1	-	-	33	0	0.00	33	4	10.81
ZMAT1	0	genome.wustl.edu	37	X	101186955	101186955	+	RNA	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	X	101186955	101186955	G	A	SNP	ZMAT1	ENST00000488347	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ZMAT1	HGNC	ENSG00000166432	tier1	-	-	10	0	0.00	4	4	50.00
ZNF160	0	genome.wustl.edu	37	19	53571879	53571879	+	Silent	SNP	A	A	G			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	53571879	53571879	A	G	SNP	ZNF160	ENST00000418871	human	ensembl	74_37	-1	known	silent	c.1908	p.L636	0.002	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF160	HGNC	ENSG00000170949	tier1	-	-	104	0	0.00	69	4	5.48
ZNF536	0	genome.wustl.edu	37	19	30936428	30936428	+	Silent	SNP	C	C	T			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	30936428	30936428	C	T	SNP	ZNF536	ENST00000355537	human	ensembl	74_37	+1	known	silent	c.1959	p.H653	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF536	HGNC	ENSG00000198597	tier1	-	-	105	0	0.00	54	30	35.71
ZNF70	0	genome.wustl.edu	37	22	24087105	24087105	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	22	24087105	24087105	G	A	SNP	ZNF70	ENST00000341976	human	ensembl	74_37	-1	known	nonsense	c.223	p.Q75*	0.143	NULL	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF70	HGNC	ENSG00000187792	tier1	-	-	65	0	0.00	69	4	5.48
ZNF876P	0	genome.wustl.edu	37	4	206477	206477	+	RNA	SNP	T	T	C			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	4	206477	206477	T	C	SNP	ZNF876P	ENST00000356347	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.003	-	-	-	no_errors	ZNF876P	HGNC	ENSG00000198155	tier1	-	-	91	0	0.00	44	21	32.31
ZSCAN5C	0	genome.wustl.edu	37	19	56720435	56720435	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-A8Q7-01A-11D-A37C-09	TCGA-VR-A8Q7-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	d7145197-3b67-4711-9569-3fee8911f214	b97bffec-210a-4795-a4f5-4711185cba7c	19	56720435	56720435	G	A	SNP	ZSCAN5C	ENST00000376267	human	ensembl	74_37	+1	known	missense	c.1357	p.A453T	0.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN5C	HGNC	ENSG00000204532	tier1	-	-	50	0	0.00	63	4	5.97
