Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	ensembl_gene_id	tier	title	header	normal_ref_reads	normal_var_reads	normal_VAF	tumor_ref_reads	tumor_var_reads	tumor_VAF
ABCC2	0	genome.wustl.edu	37	10	101554170	101554170	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	10	101554170	101554170	A	T	SNP	ABCC2	ENST00000370449	human	ensembl	74_37	+1	known	missense	c.577	p.N193Y	1.000	tigrfam_Multidrug-R_assoc	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,tigrfam_Multidrug-R_assoc	-	no_errors	ABCC2	HGNC	ENSG00000023839	tier1	-	-	38	0	0.00	60	4	6.25
ABI2	0	genome.wustl.edu	37	2	204240780	204240780	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	204240780	204240780	G	A	SNP	ABI2	ENST00000431886	human	ensembl	74_37	+1	known	missense	c.319	p.A107T	0.040	pfscan_T_SNARE_dom	pfscan_T_SNARE_dom	-	no_errors	ABI2	HGNC	ENSG00000138443	tier1	-	-	45	0	0.00	37	4	9.76
ACVR1	0	genome.wustl.edu	37	2	158617468	158617468	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	158617468	158617468	G	A	SNP	ACVR1	ENST00000263640	human	ensembl	74_37	-1	known	silent	c.1188	p.F396	0.920	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_TGF_beta_rcpt_GS,pfam_Activin_rcpt,superfamily_Kinase-like_dom,smart_TGF_beta_rcpt_GS,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_TGFB_receptor,pfscan_Prot_kinase_dom	-	no_errors	ACVR1	HGNC	ENSG00000115170	tier1	-	-	47	0	0.00	40	9	18.37
ACVR2B	0	genome.wustl.edu	37	3	38519461	38519461	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	38519461	38519461	G	C	SNP	ACVR2B	ENST00000352511	human	ensembl	74_37	+1	known	missense	c.370	p.V124L	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Activin_rcpt,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,prints_TGFB_receptor	-	no_errors	ACVR2B	HGNC	ENSG00000114739	tier1	-	-	36	0	0.00	16	5	23.81
ADH1C	0	genome.wustl.edu	37	4	100273840	100273840	+	RNA	DEL	C	C	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	100273840	100273840	C	-	DEL	ADH1C	ENST00000505942	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.196	-	-	-	no_errors	ADH1C	HGNC	ENSG00000248144	tier1			77	0	0.00	50	8	13.79
ADORA1	0	genome.wustl.edu	37	1	203134554	203134554	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	203134554	203134554	C	T	SNP	ADORA1	ENST00000309502	human	ensembl	74_37	+1	known	silent	c.507	p.C169	0.946	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Adenosn_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Adenosn_rcpt,prints_GPCR_Rhodpsn,prints_Adeno_A1_rcpt	-	no_errors	ADORA1	HGNC	ENSG00000163485	tier1	-	-	55	0	0.00	37	29	43.94
AFF1	0	genome.wustl.edu	37	4	88011154	88011154	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	88011154	88011154	C	T	SNP	AFF1	ENST00000395146	human	ensembl	74_37	+1	known	missense	c.1123	p.P375S	1.000	pfam_TF_AF4/FMR2	pfam_TF_AF4/FMR2	-	no_errors	AFF1	HGNC	ENSG00000172493				49	0	0.00	52	3	5.45
AIM1L	0	genome.wustl.edu	37	1	26670703	26670703	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	26670703	26670703	C	T	SNP	AIM1L	ENST00000374207	human	ensembl	74_37	-1	known	missense	c.481	p.G161R	0.000	NULL	superfamily_PDZ	-	no_errors	AIM1L	HGNC	ENSG00000176092	tier1	-	-	61	0	0.00	47	17	26.56
ANKS1B	0	genome.wustl.edu	37	12	99139573	99139573	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	99139573	99139573	G	A	SNP	ANKS1B	ENST00000549493	human	ensembl	74_37	-1	known	missense	c.1477	p.P493S	1.000	NULL	pfam_SAM_type1,pfam_PTB/PI_dom,pfam_SAM_2,pfam_PTB,superfamily_SAM/pointed,smart_SAM,smart_PTB/PI_dom,pfscan_PTB/PI_dom,pfscan_SAM	-	no_errors	ANKS1B	HGNC	ENSG00000185046	tier1	-	-	24	0	0.00	31	5	13.89
AOX1	0	genome.wustl.edu	37	2	201473840	201473840	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	201473840	201473840	C	T	SNP	AOX1	ENST00000374700	human	ensembl	74_37	+1	known	silent	c.1041	p.S347	0.001	pfam_Mopterin_DH_FAD-bd,superfamily_FAD-bd_2,pirsf_Ald_Oxase/xanthine_DH,tigrfam_Aldehyde_oxidase	pfam_AldOxase/xan_DH_Mopterin-bd,pfam_Mopterin_DH_FAD-bd,pfam_Ald_Oxase/Xan_DH_a/b,pfam_2Fe-2S-bd,pfam_CO_DH_flav_C,pfam_2Fe-2S_ferredoxin-type,superfamily_AldOxase/xan_DH_Mopterin-bd,superfamily_FAD-bd_2,superfamily_Ald_Oxase/Xan_DH_a/b,superfamily_2Fe-2S-bd,superfamily_CO_DH_flav_C,superfamily_2Fe-2S_ferredoxin-type,pirsf_Ald_Oxase/xanthine_DH,pfscan_2Fe-2S_ferredoxin-type,tigrfam_Aldehyde_oxidase	-	no_errors	AOX1	HGNC	ENSG00000138356	tier1	-	-	35	0	0.00	22	13	37.14
APEH	0	genome.wustl.edu	37	3	49713608	49713608	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	49713608	49713608	G	A	SNP	APEH	ENST00000296456	human	ensembl	74_37	+1	known	missense	c.562	p.D188N	0.863	NULL	pfam_Peptidase_S9,pfam_AB_hydrolase_1,pfam_Dienelactn_hydro	-	no_errors	APEH	HGNC	ENSG00000164062	tier1	-	-	42	0	0.00	10	12	54.55
APOBEC3G	0	genome.wustl.edu	37	22	39482536	39482536	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	22	39482536	39482536	G	A	SNP	APOBEC3G	ENST00000407997	human	ensembl	74_37	+1	known	missense	c.988	p.E330K	0.000	pfam_APOBEC_C,superfamily_Cytidine_deaminase-like	pfam_APOBEC_N,pfam_APOBEC_C,superfamily_Cytidine_deaminase-like	-	no_errors	APOBEC3G	HGNC	ENSG00000239713				55	0	0.00	42	3	6.67
ARID4B	0	genome.wustl.edu	37	1	235335957	235335957	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	235335957	235335957	G	A	SNP	ARID4B	ENST00000264183	human	ensembl	74_37	-1	known	missense	c.3787	p.R1263C	1.000	NULL	pfam_RBB1NT,pfam_ARID/BRIGHT_DNA-bd,pfam_Tudor-knot,superfamily_ARID/BRIGHT_DNA-bd,superfamily_Chromodomain-like,smart_Tudor,smart_ARID/BRIGHT_DNA-bd,pfscan_ARID/BRIGHT_DNA-bd	-	no_errors	ARID4B	HGNC	ENSG00000054267				41	0	0.00	42	3	6.67
ARPC2	0	genome.wustl.edu	37	2	219081926	219081926	+	RNA	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	219081926	219081926	A	G	SNP	ARPC2	ENST00000478612	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.976	-	-	-	no_errors	ARPC2	HGNC	ENSG00000163466	tier1	-	-	8	0	0.00	12	4	25.00
ASIC5	0	genome.wustl.edu	37	4	156784805	156784805	+	Frame_Shift_Del	DEL	G	G	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	156784805	156784805	G	-	DEL	ASIC5	ENST00000537611	human	ensembl	74_37	-1	known	frame_shift_del	c.142	p.H48fs	1.000	pfam_Na+channel_ASC	pfam_Na+channel_ASC,prints_Na+channel_ASC	-	no_errors	ASIC5	HGNC	ENSG00000256394	tier1			66	0	0.00	40	18	31.03
ASMT	0	genome.wustl.edu	37	X	1743260	1743260	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	X	1743260	1743260	C	T	SNP	ASMT	ENST00000381241	human	ensembl	74_37	+1	known	missense	c.343	p.R115W	0.980	pfam_O_MeTrfase_2,pirsf_COMT	pfam_O_MeTrfase_2,pirsf_COMT	-	no_errors	ASMT	HGNC	ENSG00000196433	tier1	-	-	81	0	0.00	46	22	32.35
ASTN1	0	genome.wustl.edu	37	1	176852059	176852059	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	176852059	176852059	G	A	SNP	ASTN1	ENST00000367654	human	ensembl	74_37	-1	known	missense	c.3322	p.P1108S	1.000	superfamily_Fibronectin_type3,pfscan_Fibronectin_type3	superfamily_Fibronectin_type3,smart_EG-like_dom,smart_MACPF,pfscan_Fibronectin_type3	-	no_errors	ASTN1	HGNC	ENSG00000152092	tier1	-	-	56	0	0.00	55	4	6.78
BAZ1B	0	genome.wustl.edu	37	7	72873971	72873971	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	72873971	72873971	G	A	SNP	BAZ1B	ENST00000339594	human	ensembl	74_37	-1	known	silent	c.3327	p.L1109	0.406	superfamily_ARM-type_fold	pfam_WSTF_Acf1_Cbp146,pfam_Bromodomain,pfam_Znf_PHD-finger,superfamily_Bromodomain,superfamily_Znf_FYVE_PHD,superfamily_ARM-type_fold,smart_DDT_dom_subgr,smart_Znf_PHD,smart_Bromodomain,pfscan_WSTF_Acf1_Cbp146,pfscan_Znf_PHD-finger,pfscan_Znf_RING,pfscan_DDT_dom_superfamily,pfscan_Bromodomain,prints_Bromodomain	-	no_errors	BAZ1B	HGNC	ENSG00000009954	tier1	-	-	43	0	0.00	55	4	6.78
BICC1	0	genome.wustl.edu	37	10	60273032	60273032	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	10	60273032	60273032	C	T	SNP	BICC1	ENST00000373886	human	ensembl	74_37	+1	known	silent	c.129	p.S43	1.000	NULL	pfam_KH_dom_type_1,pfam_SAM_type1,pfam_SAM_2,superfamily_SAM/pointed,smart_KH_dom,smart_SAM,pfscan_SAM,pfscan_KH_dom_type_1	-	no_errors	BICC1	HGNC	ENSG00000122870	tier1	-	-	53	0	0.00	48	4	7.69
BNIPL	0	genome.wustl.edu	37	1	151016187	151016187	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	151016187	151016187	C	T	SNP	BNIPL	ENST00000368931	human	ensembl	74_37	+1	known	missense	c.835	p.R279C	0.949	pfam_CRAL-TRIO_dom,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom	pfam_Bcl2-/adenovirus-E1B,pfam_CRAL-TRIO_dom,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom	-	no_errors	BNIPL	HGNC	ENSG00000163141	tier1	rs150118714	-	32	0	0.00	28	9	24.32
BPIFC	0	genome.wustl.edu	37	22	32810404	32810404	+	Silent	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	22	32810404	32810404	A	G	SNP	BPIFC	ENST00000300399	human	ensembl	74_37	-1	known	silent	c.1410	p.L470	0.997	pfam_Lipid-bd_serum_glycop_C,superfamily_Bactericidal_perm-incr_a/b_dom,smart_Lipid-bd_serum_glycop_C	pfam_Lipid-bd_serum_glycop_N,pfam_Lipid-bd_serum_glycop_C,superfamily_Bactericidal_perm-incr_a/b_dom,smart_Lipid-bd_serum_glycop_N,smart_Lipid-bd_serum_glycop_C	-	no_errors	BPIFC	HGNC	ENSG00000184459	tier1	-	-	62	0	0.00	71	4	5.33
BRI3	0	genome.wustl.edu	37	7	97920515	97920515	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	97920515	97920515	G	C	SNP	BRI3	ENST00000297290	human	ensembl	74_37	+1	known	missense	c.338	p.R113T	1.000	pfam_Brain_I3	pfam_Brain_I3	-	no_errors	BRI3	HGNC	ENSG00000164713	tier1	-	-	44	0	0.00	31	28	47.46
BRINP3	0	genome.wustl.edu	37	1	190067356	190067356	+	Nonsense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	190067356	190067356	G	T	SNP	BRINP3	ENST00000367462	human	ensembl	74_37	-1	known	nonsense	c.2093	p.S698*	1.000	NULL	pfam_MACPF,smart_MACPF	-	no_errors	BRINP3	HGNC	ENSG00000162670	tier1	-	-	38	0	0.00	30	7	18.92
BTN3A1	0	genome.wustl.edu	37	6	26406256	26406256	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	26406256	26406256	A	C	SNP	BTN3A1	ENST00000289361	human	ensembl	74_37	+1	known	missense	c.205	p.S69R	0.000	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_SPRY_rcpt,pfam_Ig_V-set,pfam_CD80_C2-set,superfamily_ConA-like_lec_gl_sf,smart_Ig_sub,smart_Ig_V-set_subgr,smart_PRY,smart_SPla/RYanodine_receptor_subgr,prints_Butyrophylin,pfscan_B30.2/SPRY,pfscan_Ig-like_dom	-	no_errors	BTN3A1	HGNC	ENSG00000026950				42	0	0.00	14	16	53.33
BTN3A2	0	genome.wustl.edu	37	6	26368912	26368912	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	26368912	26368912	A	C	SNP	BTN3A2	ENST00000356386	human	ensembl	74_37	+1	known	missense	c.205	p.S69R	0.000	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_V-set_subgr,pfscan_Ig-like_dom	-	no_errors	BTN3A2	HGNC	ENSG00000186470	tier1	-	-	142	0	0.00	108	19	14.96
C12orf4	0	genome.wustl.edu	37	12	4600369	4600369	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	4600369	4600369	G	A	SNP	C12orf4	ENST00000261250	human	ensembl	74_37	-1	known	missense	c.1472	p.A491V	1.000	pfam_DUF2362	pfam_DUF2362	-	no_errors	C12orf4	HGNC	ENSG00000047621	tier1	-	-	58	0	0.00	55	12	17.91
C2CD3	0	genome.wustl.edu	37	11	73881821	73881821	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	73881821	73881821	C	A	SNP	C2CD3	ENST00000334126	human	ensembl	74_37	-1	known	missense	c.17	p.G6V	0.553	NULL	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom	-	no_errors	C2CD3	HGNC	ENSG00000168014	tier1	-	-	52	0	0.00	54	15	21.74
C9orf24	0	genome.wustl.edu	37	9	34379061	34379061	+	RNA	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	34379061	34379061	G	A	SNP	C9orf24	ENST00000481295	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	C9orf24	HGNC	ENSG00000164972	tier1	-	-	42	0	0.00	27	4	12.90
CACNA1E	0	genome.wustl.edu	37	1	181680102	181680103	+	Frame_Shift_Del	DEL	AG	AG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	AG	AG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	181680102	181680103	AG	-	DEL	CACNA1E	ENST00000367573	human	ensembl	74_37	+1	known	frame_shift_del	c.1068_1069	p.R360fs	1.000:1.000	prints_VDCCAlpha1	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_hand_dom,prints_VDCCAlpha1,prints_VDCC_R_a1su	-	no_errors	CACNA1E	HGNC	ENSG00000198216	tier1			46	0	0.00	44	3	6.38
CAND2	0	genome.wustl.edu	37	3	12858877	12858877	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	12858877	12858877	C	T	SNP	CAND2	ENST00000456430	human	ensembl	74_37	+1	known	missense	c.2446	p.P816S	1.000	superfamily_ARM-type_fold	pfam_TATA-bd_TIP120,pfam_HEAT,superfamily_ARM-type_fold	-	no_errors	CAND2	HGNC	ENSG00000144712	tier1	-	-	63	0	0.00	36	17	32.08
CCR9	0	genome.wustl.edu	37	3	45943064	45943064	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	45943064	45943064	G	A	SNP	CCR9	ENST00000357632	human	ensembl	74_37	+1	known	missense	c.784	p.V262I	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Chemokine_CCR9,prints_Chemokine_rcpt,prints_Chemokine_CCR7,prints_ATII_rcpt,prints_Chemokine_CCRL1,prints_Chemokine_CXCR4	-	no_errors	CCR9	HGNC	ENSG00000173585	tier1	rs202070482	-	46	0	0.00	28	11	28.21
CD207	0	genome.wustl.edu	37	2	71058196	71058196	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	71058196	71058196	G	T	SNP	CD207	ENST00000410009	human	ensembl	74_37	-1	known	silent	c.972	p.V324	0.000	NULL	pfam_C-type_lectin,superfamily_C-type_lectin_fold,smart_C-type_lectin,pfscan_C-type_lectin	-	no_errors	CD207	HGNC	ENSG00000116031	tier1	-	-	71	0	0.00	69	5	6.76
CD320	0	genome.wustl.edu	37	19	8367714	8367714	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	8367714	8367714	G	T	SNP	CD320	ENST00000301458	human	ensembl	74_37	-1	known	missense	c.653	p.S218Y	0.000	NULL	pfam_LDrepeatLR_classA_rpt,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,pfscan_LDrepeatLR_classA_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	CD320	HGNC	ENSG00000167775	tier1	-	-	63	0	0.00	27	4	12.90
CD47	0	genome.wustl.edu	37	3	107762288	107762289	+	RNA	INS	-	-	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	107762288	107762289	-	A	INS	CD47	ENST00000471694	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002:0.021	-	-	-	no_errors	CD47	HGNC	ENSG00000196776	tier1			43	0	0.00	20	4	16.67
CDH18	0	genome.wustl.edu	37	5	19591263	19591263	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	19591263	19591263	G	T	SNP	CDH18	ENST00000274170	human	ensembl	74_37	-1	known	missense	c.902	p.A301D	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH18	HGNC	ENSG00000145526				41	0	0.00	28	2	6.67
CDK10	0	genome.wustl.edu	37	16	89762095	89762095	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	89762095	89762095	C	A	SNP	CDK10	ENST00000353379	human	ensembl	74_37	+1	known	missense	c.1078	p.P360T	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDK10	HGNC	ENSG00000185324	tier1	-	-	97	0	0.00	65	46	41.44
CDKN2A	0	genome.wustl.edu	37	9	21974744	21974744	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	21974744	21974744	A	G	SNP	CDKN2A	ENST00000446177	human	ensembl	74_37	-1	known	missense	c.83	p.V28A	1.000	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	superfamily_Ankyrin_rpt-contain_dom,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	CDKN2A	HGNC	ENSG00000147889				23	0	0.00	9	7	43.75
CEP290	0	genome.wustl.edu	37	12	88487680	88487681	+	Frame_Shift_Ins	INS	-	-	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	88487680	88487681	-	T	INS	CEP290	ENST00000309041	human	ensembl	74_37	-1	known	frame_shift_ins	c.3182_3181	p.I1061fs	1.000:1.000	NULL	NULL	-	no_errors	CEP290	HGNC	ENSG00000198707	tier1			60	0	0.00	37	2	5.13
CLEC18B	0	genome.wustl.edu	37	16	74455135	74455136	+	Frame_Shift_Ins	INS	-	-	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	74455135	74455136	-	C	INS	CLEC18B	ENST00000339953	human	ensembl	74_37	-1	known	frame_shift_ins	c.34_33	p.H11fs	0.004:0.003	NULL	pfam_CAP_domain,pfam_C-type_lectin,superfamily_CAP_domain,superfamily_C-type_lectin_fold,smart_Allrgn_V5/Tpx1,smart_EG-like_dom,smart_C-type_lectin,pfscan_EG-like_dom,pfscan_C-type_lectin,prints_Allrgn_V5/Tpx1	-	no_errors	CLEC18B	HGNC	ENSG00000140839	tier1			166	0	0.00	92	35	27.56
CLN3	0	genome.wustl.edu	37	16	28488869	28488869	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	28488869	28488869	G	A	SNP	CLN3	ENST00000359984	human	ensembl	74_37	-1	known	missense	c.1285	p.P429S	1.000	pfam_Battenin_disease_Cln3,superfamily_MFS_dom_general_subst_transpt,pirsf_Battenin_disease_Cln3_subgr,prints_Battenin_disease_Cln3	pfam_Battenin_disease_Cln3,superfamily_MFS_dom_general_subst_transpt,pirsf_Battenin_disease_Cln3_subgr,prints_Battenin_disease_Cln3	-	no_errors	CLN3	HGNC	ENSG00000188603				23	0	0.00	25	3	10.71
CLSTN2	0	genome.wustl.edu	37	3	140284997	140284999	+	In_Frame_Del	DEL	GAG	GAG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	GAG	GAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	140284997	140284999	GAG	-	DEL	CLSTN2	ENST00000458420	human	ensembl	74_37	+1	known	in_frame_del	c.2770_2772	p.E927in_frame_del	0.989:0.994:0.995	NULL	pfam_Cadherin,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CLSTN2	HGNC	ENSG00000158258	tier1			52	0	0.00	31	2	6.06
COL4A5	0	genome.wustl.edu	37	X	107924125	107924125	+	Silent	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	X	107924125	107924125	A	G	SNP	COL4A5	ENST00000328300	human	ensembl	74_37	+1	known	silent	c.4026	p.G1342	1.000	pfam_Collagen	pfam_Collagen,pfam_Collagen_VI_NC,superfamily_C-type_lectin_fold,smart_Collagen_VI_NC	-	no_errors	COL4A5	HGNC	ENSG00000188153	tier1	-	-	32	0	0.00	38	4	9.30
COX7A2	0	genome.wustl.edu	37	6	75953544	75953544	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	75953544	75953544	C	T	SNP	COX7A2	ENST00000370081	human	ensembl	74_37	-1	known	missense	c.3	p.M1I	0.079	NULL	pfam_Cyt_c_oxidase_su7a,superfamily_Cyt_c_oxidase_su7a	-	no_errors	COX7A2	HGNC	ENSG00000112695	tier1	-	-	61	0	0.00	71	4	5.33
CSF1R	0	genome.wustl.edu	37	5	149459879	149459879	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	149459879	149459879	C	T	SNP	CSF1R	ENST00000286301	human	ensembl	74_37	-1	known	missense	c.328	p.V110M	0.000	pirsf_Tyr_kinase_CSF1/PDGF_rcpt	pirsf_Tyr_kinase_CSF1/PDGF_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Immunoglobulin,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	CSF1R	HGNC	ENSG00000182578	tier1	-	-	17	0	0.00	21	5	19.23
CSF3	0	genome.wustl.edu	37	17	38173192	38173193	+	Frame_Shift_Del	DEL	CG	CG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	CG	CG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	38173192	38173193	CG	-	DEL	CSF3	ENST00000225474	human	ensembl	74_37	+1	known	frame_shift_del	c.604_605	p.R202fs	0.998:0.993	pfam_IL-6/IL-23/GCSF/MGF,superfamily_4_helix_cytokine-like_core,smart_IL-6/IL-23/GCSF/MGF,pirsf_IL-6/IL-23/GCSF/MGF,prints_IL-6/IL-23/GCSF/MGF	pfam_IL-6/IL-23/GCSF/MGF,superfamily_4_helix_cytokine-like_core,smart_IL-6/IL-23/GCSF/MGF,pirsf_IL-6/IL-23/GCSF/MGF,prints_IL-6/IL-23/GCSF/MGF	-	no_errors	CSF3	HGNC	ENSG00000108342	tier1			49	0	0.00	403	84	17.25
CSMD2	0	genome.wustl.edu	37	1	34080136	34080136	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	34080136	34080136	C	A	SNP	CSMD2	ENST00000373381	human	ensembl	74_37	-1	known	missense	c.6101	p.C2034F	1.000	pfam_CUB_dom,superfamily_CUB_dom,smart_CUB_dom,pfscan_CUB_dom	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD2	HGNC	ENSG00000121904	tier1	-	-	64	0	0.00	25	26	50.98
CSMD3	0	genome.wustl.edu	37	8	113256779	113256779	+	Missense_Mutation	SNP	T	T	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	113256779	113256779	T	G	SNP	CSMD3	ENST00000297405	human	ensembl	74_37	-1	known	missense	c.10246	p.T3416P	1.000	pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Sushi_SCR_CCP	pfam_CUB_dom,pfam_Sushi_SCR_CCP,superfamily_CUB_dom,superfamily_Sushi_SCR_CCP,smart_CUB_dom,smart_Sushi_SCR_CCP,pfscan_CUB_dom,pfscan_Sushi_SCR_CCP	-	no_errors	CSMD3	HGNC	ENSG00000164796	tier1	-	-	59	0	0.00	52	9	14.75
CWC22	0	genome.wustl.edu	37	2	180851528	180851528	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	180851528	180851528	C	T	SNP	CWC22	ENST00000295749	human	ensembl	74_37	-1	known	missense	c.100	p.E34K	0.160	NULL	pfam_MIF4G-like_typ-3,pfam_Initiation_fac_eIF4g_MI,superfamily_ARM-type_fold,smart_MIF4G-like_typ-3,smart_Initiation_fac_eIF4g_MI	-	no_errors	CWC22	HGNC	ENSG00000163510	tier1	-	-	40	0	0.00	52	4	7.14
CYB5D1	0	genome.wustl.edu	37	17	7762921	7762921	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	7762921	7762921	G	T	SNP	CYB5D1	ENST00000332439	human	ensembl	74_37	+1	known	silent	c.678	p.T226	0.544	NULL	pfam_Cyt_B5-like_heme/steroid-bd,superfamily_Cyt_B5-like_heme/steroid-bd,pfscan_Cyt_B5-like_heme/steroid-bd	-	no_errors	CYB5D1	HGNC	ENSG00000182224	tier1	-	-	40	0	0.00	18	3	14.29
DAK	0	genome.wustl.edu	37	11	61105513	61105513	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	61105513	61105513	G	A	SNP	DAK	ENST00000394900	human	ensembl	74_37	+1	known	missense	c.104	p.R35H	1.000	pfam_Dak1,tigrfam_DhaK_ATP	pfam_Dak1,pfam_DhaL_dom,superfamily_DhaL_dom,tigrfam_DhaK_ATP	-	no_errors	DAK	HGNC	ENSG00000149476				18	0	0.00	17	3	15.00
DDX60	0	genome.wustl.edu	37	4	169229302	169229302	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	169229302	169229302	A	-	DEL	DDX60	ENST00000393743	human	ensembl	74_37	-1	known	frame_shift_del	c.119	p.L40fs	0.999	NULL	pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_Helicase/UvrB_dom,pfam_Helicase_C,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DDX60	HGNC	ENSG00000137628	tier1			60	0	0.00	39	4	9.30
DNM1P47	0	genome.wustl.edu	37	15	102304772	102304772	+	RNA	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	102304772	102304772	T	C	SNP	DNM1P47	ENST00000561463	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.984	-	-	-	no_errors	DNM1P47	HGNC	ENSG00000259660				48	0	0.00	42	4	8.70
DOCK4	0	genome.wustl.edu	37	7	111381677	111381677	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	111381677	111381677	G	T	SNP	DOCK4	ENST00000428084	human	ensembl	74_37	-1	known	missense	c.4838	p.P1613H	1.000	NULL	pfam_DOCK_C,pfam_SH3_2,superfamily_SH3_domain,superfamily_Rho_GTPase_activation_prot,superfamily_C2_dom,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	DOCK4	HGNC	ENSG00000128512	tier1	-	-	27	0	0.00	35	4	10.26
DST	0	genome.wustl.edu	37	6	56420335	56420335	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	56420335	56420335	C	T	SNP	DST	ENST00000370754	human	ensembl	74_37	-1	known	missense	c.14851	p.A4951T	1.000	superfamily_ABC1_TM_dom,smart_Spectrin/alpha-actinin	pfam_Spectrin_repeat,pfam_Plectin_repeat,pfam_CH-domain,pfam_GAS2_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_GAS2_dom,superfamily_ABC1_TM_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Plectin_repeat,smart_EF_hand_dom,smart_GAS2_dom,pfscan_CH-domain,pfscan_EF_hand_dom	-	no_errors	DST	HGNC	ENSG00000151914				36	0	0.00	45	4	8.16
DUOX2	0	genome.wustl.edu	37	15	45391892	45391892	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	45391892	45391892	C	T	SNP	DUOX2	ENST00000389039	human	ensembl	74_37	-1	known	missense	c.3383	p.R1128H	1.000	pfam_Fe3_Rdtase_TM_dom	pfam_Haem_peroxidase_animal,pfam_Fe_red_NAD-bd_6,pfam_FAD-bd_8,pfam_Fe3_Rdtase_TM_dom,pfam_EF_hand_dom,superfamily_Haem_peroxidase,superfamily_Riboflavin_synthase-like_b-brl,smart_EF_hand_dom,pfscan_EF_hand_dom,pfscan_Haem_peroxidase_animal,prints_Haem_peroxidase_animal_subgr,prints_Recoverin	-	no_errors	DUOX2	HGNC	ENSG00000140279	tier1	-	-	41	0	0.00	38	4	9.52
DUSP10	0	genome.wustl.edu	37	1	221875156	221875157	+	RNA	INS	-	-	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	221875156	221875157	-	A	INS	DUSP10	ENST00000468085	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002:0.000	-	-	-	no_errors	DUSP10	HGNC	ENSG00000143507	tier1			21	0	0.00	20	2	9.09
DUSP12	0	genome.wustl.edu	37	1	161719712	161719712	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	161719712	161719712	G	A	SNP	DUSP12	ENST00000367943	human	ensembl	74_37	+1	known	missense	c.121	p.A41T	0.988	pfam_Dual-sp_phosphatase_cat-dom,smart_Dual-sp_phosphatase_subgr_cat,pirsf_DUSP12,pfscan_Dual-sp_phosphatase_subgr_cat	pfam_Dual-sp_phosphatase_cat-dom,smart_Dual-sp_phosphatase_subgr_cat,pirsf_DUSP12,pfscan_Znf_C2H2,pfscan_Tyr/Dual-sp_Pase,pfscan_Dual-sp_phosphatase_subgr_cat	-	no_errors	DUSP12	HGNC	ENSG00000081721	tier1	-	-	61	0	0.00	73	5	6.41
EFR3B	0	genome.wustl.edu	37	2	25358396	25358396	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	25358396	25358396	C	T	SNP	EFR3B	ENST00000403714	human	ensembl	74_37	+1	known	missense	c.1372	p.R458C	1.000	superfamily_ARM-type_fold	superfamily_ARM-type_fold	-	no_errors	EFR3B	HGNC	ENSG00000084710				36	0	0.00	31	2	6.06
EHMT1	0	genome.wustl.edu	37	9	140710455	140710455	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	140710455	140710455	C	T	SNP	EHMT1	ENST00000460843	human	ensembl	74_37	+1	known	silent	c.3315	p.C1105	1.000	pfam_Pre-SET_dom,smart_Pre-SET_Zn-bd_sub,pfscan_Pre-SET_dom	pfam_Ankyrin_rpt,pfam_SET_dom,pfam_Pre-SET_dom,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Pre-SET_Zn-bd_sub,smart_SET_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_SET_dom,pfscan_Pre-SET_dom,prints_Ankyrin_rpt	-	no_errors	EHMT1	HGNC	ENSG00000181090				51	0	0.00	77	5	6.02
ENSG00000212857	0	genome.wustl.edu	37	GL000212.1	65028	65028	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	GL000212.1	65028	65028	G	A	SNP	ENSG00000212857	ENST00000391545	human	ensembl	74_37	+1	known	silent	c.777	p.T259	NULL	NULL	NULL	-	no_errors	AL356585.1	Clone_based_ensembl_gene	ENSG00000212857	tier1	-	-	73	0	0.00	30	22	41.51
ENSG00000232274	0	genome.wustl.edu	37	1	143189125	143189125	+	RNA	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	143189125	143189125	G	A	SNP	ENSG00000232274	ENST00000447389	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.014	-	-	-	no_errors	RP11-782C8.2	Clone_based_vega_gene	ENSG00000232274	tier1	rs201126579	-	14	0	0.00	14	6	30.00
ENSG00000255532	0	genome.wustl.edu	37	11	49401015	49401015	+	RNA	SNP	T	T	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	49401015	49401015	T	A	SNP	ENSG00000255532	ENST00000529081	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	CTD-2026G22.1	Clone_based_vega_gene	ENSG00000255532	tier1	-	-	73	0	0.00	73	4	5.19
ENSG00000259647	0	genome.wustl.edu	37	15	30297722	30297722	+	RNA	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	30297722	30297722	G	A	SNP	ENSG00000259647	ENST00000561392	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-143J24.1	Clone_based_vega_gene	ENSG00000259647	tier1	-	-	34	0	0.00	12	4	25.00
EPS8L3	0	genome.wustl.edu	37	1	110294817	110294817	+	Splice_Site	SNP	T	T	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	110294817	110294817	T	G	SNP	EPS8L3	ENST00000369805	human	ensembl	74_37	-1	known	splice_site	c.1239-2	e14-2	0.000	-	-	-	no_errors	EPS8L3	HGNC	ENSG00000198758	tier1	-	-	68	0	0.00	45	5	10.00
EXOC6	0	genome.wustl.edu	37	10	94714402	94714402	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	10	94714402	94714402	C	T	SNP	EXOC6	ENST00000371547	human	ensembl	74_37	+1	known	silent	c.1590	p.D530	0.997	pfam_Sec15,pirsf_Sec15	pfam_Sec15,pirsf_Sec15	-	no_errors	EXOC6	HGNC	ENSG00000138190	tier1	rs146699258	-	77	0	0.00	54	10	15.62
EXOSC2	0	genome.wustl.edu	37	9	133574844	133574844	+	RNA	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	133574844	133574844	C	G	SNP	EXOSC2	ENST00000463488	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	EXOSC2	HGNC	ENSG00000130713	tier1	-	-	31	0	0.00	10	28	73.68
FAM124A	0	genome.wustl.edu	37	13	51854620	51854620	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	13	51854620	51854620	G	A	SNP	FAM124A	ENST00000280057	human	ensembl	74_37	+1	known	missense	c.977	p.G326D	0.000	NULL	NULL	-	no_errors	FAM124A	HGNC	ENSG00000150510	tier1	-	-	39	0	0.00	71	22	23.66
FAT3	0	genome.wustl.edu	37	11	92568181	92568181	+	Silent	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	92568181	92568181	C	A	SNP	FAT3	ENST00000298047	human	ensembl	74_37	+1	known	silent	c.10017	p.P3339	0.007	superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT3	HGNC	ENSG00000165323	tier1	-	-	50	0	0.00	31	13	29.55
FBXL16	0	genome.wustl.edu	37	16	747263	747265	+	In_Frame_Del	DEL	TGG	TGG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	TGG	TGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	747263	747265	TGG	-	DEL	FBXL16	ENST00000324361	human	ensembl	74_37	-1	known	in_frame_del	c.143_141	p.CQ47in_frame_delW	1.000:1.000:1.000	NULL	superfamily_F-box_dom,smart_Leu-rich_rpt_Cys-con_subtyp	-	no_errors	FBXL16	HGNC	ENSG00000127585	tier1			8	0	0.00	2	3	60.00
FCRL4	0	genome.wustl.edu	37	1	157545291	157545291	+	RNA	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	157545291	157545291	C	T	SNP	FCRL4	ENST00000448509	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	FCRL4	HGNC	ENSG00000163518	tier1	-	-	29	0	0.00	16	7	30.43
FOXI3	0	genome.wustl.edu	37	2	88751690	88751690	+	RNA	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	88751690	88751690	G	A	SNP	FOXI3	ENST00000398142	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	FOXI3	HGNC	ENSG00000214336				18	0	0.00	35	5	12.50
FPR1	0	genome.wustl.edu	37	19	52249969	52249969	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	52249969	52249969	G	A	SNP	FPR1	ENST00000304748	human	ensembl	74_37	-1	known	silent	c.279	p.F93	0.889	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Formyl_pep_rcpt,prints_GPCR_Rhodpsn,prints_Anphylx_rcpt	-	no_errors	FPR1	HGNC	ENSG00000171051	tier1	-	-	75	0	0.00	38	31	44.93
FRMD5	0	genome.wustl.edu	37	15	44184264	44184264	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	44184264	44184264	C	T	SNP	FRMD5	ENST00000417257	human	ensembl	74_37	-1	known	missense	c.643	p.V215M	1.000	pfscan_FERM_domain	pfam_FERM_N,pfam_FERM_central,pfam_FERM-adjacent,pfam_FERM_PH-like_C,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain,prints_Band_41_fam,prints_Ez/rad/moesin_like	-	no_errors	FRMD5	HGNC	ENSG00000171877	tier1	-	-	16	0	0.00	4	5	55.56
FUT1	0	genome.wustl.edu	37	19	49254520	49254520	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	49254520	49254520	G	A	SNP	FUT1	ENST00000310160	human	ensembl	74_37	-1	known	missense	c.19	p.R7C	0.003	NULL	pfam_Glyco_trans_11	-	no_errors	FUT1	HGNC	ENSG00000174951				28	0	0.00	24	2	7.69
GABRB3	0	genome.wustl.edu	37	15	26866507	26866507	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	26866507	26866507	G	A	SNP	GABRB3	ENST00000299267	human	ensembl	74_37	-1	known	missense	c.415	p.R139C	1.000	pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,tigrfam_Neur_channel	pfam_Neurotrans-gated_channel_TM,pfam_Neur_chan_lig-bd,superfamily_Neur_chan_lig-bd,superfamily_Neurotrans-gated_channel_TM,prints_GABAA_rcpt,prints_GABAAb_rcpt,prints_Neur_channel,prints_GABBAg_rcpt,tigrfam_Neur_channel	-	no_errors	GABRB3	HGNC	ENSG00000166206	tier1	-	-	32	0	0.00	34	11	24.44
GAREM	0	genome.wustl.edu	37	18	29867784	29867784	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	18	29867784	29867784	G	T	SNP	GAREM	ENST00000269209	human	ensembl	74_37	-1	known	missense	c.776	p.P259Q	0.997	NULL	superfamily_SAM/pointed	-	no_errors	GAREM	HGNC	ENSG00000141441	tier1	-	-	37	0	0.00	42	4	8.70
GARNL3	0	genome.wustl.edu	37	9	130155584	130155584	+	RNA	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	130155584	130155584	T	C	SNP	GARNL3	ENST00000496711	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.972	-	-	-	no_errors	GARNL3	HGNC	ENSG00000136895	tier1	-	-	57	0	0.00	52	4	7.14
GPR32	0	genome.wustl.edu	37	19	51274851	51274851	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	51274851	51274851	A	C	SNP	GPR32	ENST00000270590	human	ensembl	74_37	+1	known	missense	c.994	p.T332P	0.018	prints_Formyl_pep_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Formyl_pep_rcpt	-	no_errors	GPR32	HGNC	ENSG00000142511	tier1	rs201404376	-	60	0	0.00	50	5	9.09
GRID2	0	genome.wustl.edu	37	4	94145855	94145855	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	94145855	94145855	A	C	SNP	GRID2	ENST00000282020	human	ensembl	74_37	+1	known	missense	c.1054	p.S352R	0.995	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_Iontro_glu_rcpt,pfam_ANF_lig-bd_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRID2	HGNC	ENSG00000152208	tier1	-	-	32	0	0.00	27	13	32.50
GRIN2A	0	genome.wustl.edu	37	16	9923301	9923301	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	9923301	9923301	C	T	SNP	GRIN2A	ENST00000330684	human	ensembl	74_37	-1	known	silent	c.1986	p.V662	1.000	pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,smart_Iontro_glu_rcpt	pfam_NMDAR2_C,pfam_Iontro_glu_rcpt,pfam_SBP_bac_3,pfam_Glu_rcpt_Glu/Gly-bd,pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I,smart_Iontro_glu_rcpt,smart_Glu_rcpt_Glu/Gly-bd,prints_NMDA_rcpt	-	no_errors	GRIN2A	HGNC	ENSG00000183454	tier1	-	-	71	0	0.00	46	14	23.33
GSTM3	0	genome.wustl.edu	37	1	110282849	110282849	+	RNA	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	110282849	110282849	A	G	SNP	GSTM3	ENST00000488824	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	GSTM3	HGNC	ENSG00000134202	tier1	-	-	28	0	0.00	14	6	30.00
GTDC1	0	genome.wustl.edu	37	2	144764923	144764923	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	144764923	144764923	T	C	SNP	GTDC1	ENST00000344850	human	ensembl	74_37	-1	known	missense	c.701	p.E234G	0.000	NULL	pfam_GlycosylTrfase_1_N,pfam_Glyco_trans_1	-	no_errors	GTDC1	HGNC	ENSG00000121964	tier1	-	-	58	0	0.00	40	8	16.67
HAVCR2	0	genome.wustl.edu	37	5	156535950	156535950	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	156535950	156535950	C	T	SNP	HAVCR2	ENST00000307851	human	ensembl	74_37	-1	known	silent	c.45	p.L15	0.091	pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	HAVCR2	HGNC	ENSG00000135077	tier1	-	-	78	0	0.00	78	6	7.14
HECTD4	0	genome.wustl.edu	37	12	112690234	112690234	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	112690234	112690234	G	T	SNP	HECTD4	ENST00000377560	human	ensembl	74_37	-1	known	silent	c.3030	p.R1010	1.000	NULL	pfam_HECT,superfamily_HECT,superfamily_ConA-like_lec_gl_sf,smart_HECT,pfscan_HECT	-	no_errors	HECTD4	HGNC	ENSG00000173064	tier1	-	-	38	0	0.00	35	10	22.22
HLA-DRB5	0	genome.wustl.edu	37	6	32487265	32487265	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	32487265	32487265	C	G	SNP	HLA-DRB5	ENST00000374975	human	ensembl	74_37	-1	known	missense	c.534	p.Q178H	0.000	pfam_Ig_C1-set,smart_Ig_C1-set,pfscan_Ig-like_dom	pfam_MHC_II_b_N,pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_MHC_II_b_N,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	HLA-DRB5	HGNC	ENSG00000198502	tier1	rs139485758	-	15	0	0.00	11	5	31.25
HPS5	0	genome.wustl.edu	37	11	18320503	18320503	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	18320503	18320503	C	T	SNP	HPS5	ENST00000349215	human	ensembl	74_37	-1	known	missense	c.1000	p.A334T	1.000	pirsf_BLOC-2_complex_Hps5_subunit	superfamily_WD40_repeat_dom,pirsf_BLOC-2_complex_Hps5_subunit	-	no_errors	HPS5	HGNC	ENSG00000110756	tier1	-	-	45	0	0.00	43	4	8.51
HSF1	0	genome.wustl.edu	37	8	145537251	145537251	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	145537251	145537251	G	T	SNP	HSF1	ENST00000528838	human	ensembl	74_37	+1	known	missense	c.1197	p.Q399H	1.000	pfam_Vert_HSTF_C	pfam_Vert_HSTF_C,pfam_HSF_DNA-bd,smart_HSF_DNA-bd,prints_HSF_DNA-bd	-	no_errors	HSF1	HGNC	ENSG00000185122				23	0	0.00	45	4	8.16
HYDIN	0	genome.wustl.edu	37	16	71220807	71220808	+	Frame_Shift_Ins	INS	-	-	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	71220807	71220808	-	T	INS	HYDIN	ENST00000538248	human	ensembl	74_37	-1	known	frame_shift_ins	c.73_72	p.L24fs	0.140:0.169	NULL	superfamily_PapD-like	-	no_errors	HYDIN	HGNC	ENSG00000157423	tier1			34	0	0.00	33	3	8.33
IGF2R	0	genome.wustl.edu	37	6	160523575	160523575	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	160523575	160523575	C	T	SNP	IGF2R	ENST00000356956	human	ensembl	74_37	+1	known	silent	c.6867	p.P2289	0.007	NULL	pfam_CIMR,pfam_FN_type2_col-bd,superfamily_Man6P_isomerase_rcpt-bd_dom,superfamily_Kringle-like,smart_FN_type2_col-bd,pfscan_FN_type2_col-bd	-	no_errors	IGF2R	HGNC	ENSG00000197081	tier1	rs149900660	-	55	0	0.00	31	21	40.38
IL22RA1	0	genome.wustl.edu	37	1	24447325	24447325	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	24447325	24447325	G	T	SNP	IL22RA1	ENST00000270800	human	ensembl	74_37	-1	novel	silent	c.1695	p.G565	0.987	NULL	pfam_Interferon_alpha/beta_rcpt_bsu,superfamily_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL22RA1	HGNC	ENSG00000142677	tier1	-	-	36	0	0.00	29	12	29.27
IL31RA	0	genome.wustl.edu	37	5	55212740	55212740	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	55212740	55212740	C	T	SNP	IL31RA	ENST00000447346	human	ensembl	74_37	+1	known	missense	c.2087	p.P696L	0.004	NULL	pfam_Fibronectin_type3,pfam_IL-6_rcpt_alpha-bd,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	IL31RA	HGNC	ENSG00000164509				39	0	0.00	36	3	7.69
INTU	0	genome.wustl.edu	37	4	128564917	128564917	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	128564917	128564917	A	-	DEL	INTU	ENST00000335251	human	ensembl	74_37	+1	known	frame_shift_del	c.388	p.N132fs	1.000	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	INTU	HGNC	ENSG00000164066	tier1			44	0	0.00	31	2	6.06
IRF2BP2	0	genome.wustl.edu	37	1	234744487	234744487	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	234744487	234744487	G	A	SNP	IRF2BP2	ENST00000366609	human	ensembl	74_37	-1	novel	missense	c.754	p.R252C	0.052	pfam_Interferon_reg_fac2-bd1_2_Znf	pfam_Interferon_reg_fac2-bd1_2_Znf	-	no_errors	IRF2BP2	HGNC	ENSG00000168264	tier1	-	-	9	0	0.00	3	7	70.00
IZUMO4	0	genome.wustl.edu	37	19	2097670	2097670	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	2097670	2097670	C	T	SNP	IZUMO4	ENST00000395296	human	ensembl	74_37	+1	known	missense	c.457	p.R153C	0.000	NULL	NULL	-	no_errors	IZUMO4	HGNC	ENSG00000099840	tier1	-	-	19	0	0.00	12	6	33.33
JARID2	0	genome.wustl.edu	37	6	15513490	15513490	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	15513490	15513490	G	A	SNP	JARID2	ENST00000341776	human	ensembl	74_37	+1	known	missense	c.3287	p.R1096H	1.000	NULL	pfam_JmjC_dom,pfam_ARID/BRIGHT_DNA-bd,pfam_TF_JmjN,pfam_Znf_C5HC2,superfamily_ARID/BRIGHT_DNA-bd,smart_TF_JmjN,smart_ARID/BRIGHT_DNA-bd,smart_JmjC_dom,pfscan_TF_JmjN,pfscan_JmjC_dom,pfscan_ARID/BRIGHT_DNA-bd	-	no_errors	JARID2	HGNC	ENSG00000008083				34	0	0.00	21	2	8.70
KAT2B	0	genome.wustl.edu	37	3	20136842	20136842	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	20136842	20136842	C	A	SNP	KAT2B	ENST00000263754	human	ensembl	74_37	+1	known	missense	c.518	p.T173N	1.000	pirsf_Hist_acetylase_PCAF,pfam_PCAF_N	pirsf_Hist_acetylase_PCAF,pfam_PCAF_N,pfam_Bromodomain,pfam_GNAT_dom,superfamily_Bromodomain,superfamily_Acyl_CoA_acyltransferase,smart_Bromodomain,prints_Bromodomain,pfscan_Bromodomain,pfscan_GNAT_dom	-	no_errors	KAT2B	HGNC	ENSG00000114166	tier1	-	-	66	0	0.00	33	10	23.26
KIAA1024	0	genome.wustl.edu	37	15	79749285	79749285	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	79749285	79749285	A	C	SNP	KIAA1024	ENST00000305428	human	ensembl	74_37	+1	known	missense	c.796	p.N266H	1.000	NULL	pfam_UPF0258	-	no_errors	KIAA1024	HGNC	ENSG00000169330	tier1	-	-	24	0	0.00	17	3	15.00
KIAA1755	0	genome.wustl.edu	37	20	36845807	36845807	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	36845807	36845807	C	T	SNP	KIAA1755	ENST00000279024	human	ensembl	74_37	-1	known	missense	c.2749	p.G917R	0.000	NULL	superfamily_CRAL-TRIO_dom	-	no_errors	KIAA1755	HGNC	ENSG00000149633	tier1	-	-	60	0	0.00	73	4	5.19
KLHL23	0	genome.wustl.edu	37	2	170592353	170592353	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	170592353	170592353	A	T	SNP	KLHL23	ENST00000272797	human	ensembl	74_37	+1	known	missense	c.829	p.I277L	1.000	pfam_Kelch_1,smart_Kelch_1,pirsf_Kelch-like_gigaxonin	pfam_Kelch_1,pfam_BTB_POZ,pfam_BACK,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like	-	no_errors	KLHL23	HGNC	ENSG00000213160	tier1	-	-	42	0	0.00	38	20	34.48
KLK12	0	genome.wustl.edu	37	19	51532672	51532672	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	51532672	51532672	T	A	SNP	KLK12	ENST00000250351	human	ensembl	74_37	-1	known	missense	c.633	p.Q211H	0.999	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	KLK12	HGNC	ENSG00000186474	tier1	-	-	51	0	0.00	38	15	28.30
KRTAP10-5	0	genome.wustl.edu	37	21	46000435	46000435	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	21	46000435	46000435	G	A	SNP	KRTAP10-5	ENST00000400372	human	ensembl	74_37	-1	known	silent	c.21	p.S7	0.777	NULL	NULL	-	no_errors	KRTAP10-5	HGNC	ENSG00000241123	tier1	-	-	149	0	0.00	79	34	30.09
LAMC1	0	genome.wustl.edu	37	1	183077522	183077522	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	183077522	183077522	G	T	SNP	LAMC1	ENST00000258341	human	ensembl	74_37	+1	known	missense	c.835	p.D279Y	1.000	pfam_Laminin_N,smart_Laminin_N,pfscan_Laminin_N	pfam_Laminin_N,pfam_EGF_laminin,pfam_Laminin_B_type_IV,smart_Laminin_N,smart_EGF_laminin,smart_EG-like_dom,smart_Laminin_B_subgr,pfscan_Laminin_B_type_IV,pfscan_EGF_laminin,pfscan_Laminin_N	-	no_errors	LAMC1	HGNC	ENSG00000135862	tier1	-	-	91	0	0.00	92	16	14.81
LINC00326	0	genome.wustl.edu	37	6	133421320	133421320	+	RNA	SNP	T	T	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	133421320	133421320	T	A	SNP	LINC00326	ENST00000434443	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.011	-	-	-	no_errors	LINC00326	HGNC	ENSG00000231023	tier1	-	-	59	0	0.00	56	4	6.67
LINGO2	0	genome.wustl.edu	37	9	27950666	27950666	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	27950666	27950666	G	T	SNP	LINGO2	ENST00000308675	human	ensembl	74_37	-1	known	missense	c.4	p.L2I	1.000	NULL	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Ig_V-set,pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LINGO2	HGNC	ENSG00000174482				35	0	0.00	25	2	7.41
LOC100996870	0	genome.wustl.edu	37	9	66466650	66466650	+	RNA	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	66466650	66466650	G	C	SNP	LOC100996870	ENST00000424345	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.105	-	-	-	no_errors	RP11-262H14.1	Clone_based_vega_gene	ENSG00000238113	tier1	rs1133399	-	12	0	0.00	3	4	57.14
LOC643406	0	genome.wustl.edu	37	20	5454483	5454483	+	RNA	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	5454483	5454483	G	A	SNP	LOC643406	ENST00000430097	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP5-828H9.1	Clone_based_vega_gene	ENSG00000230563	tier1	rs201294214	-	69	0	0.00	42	20	32.26
LPIN3	0	genome.wustl.edu	37	20	39980508	39980508	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	39980508	39980508	G	T	SNP	LPIN3	ENST00000373257	human	ensembl	74_37	+1	known	missense	c.1150	p.D384Y	1.000	NULL	pfam_LNS2,pfam_Lipin_N,superfamily_HAD-like_dom,smart_LNS2	-	no_errors	LPIN3	HGNC	ENSG00000132793	tier1	-	-	55	0	0.00	26	15	36.59
LRFN2	0	genome.wustl.edu	37	6	40400534	40400534	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	40400534	40400534	G	T	SNP	LRFN2	ENST00000338305	human	ensembl	74_37	-1	known	missense	c.319	p.L107I	1.000	smart_Leu-rich_rpt_typical-subtyp	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	LRFN2	HGNC	ENSG00000156564				33	0	0.00	27	2	6.90
LRRC17	0	genome.wustl.edu	37	7	102575006	102575006	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	102575006	102575006	G	A	SNP	LRRC17	ENST00000339431	human	ensembl	74_37	+1	known	missense	c.646	p.E216K	0.059	NULL	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C	-	no_errors	LRRC17	HGNC	ENSG00000128606				71	0	0.00	85	7	7.61
LRRC53	0	genome.wustl.edu	37	1	74946499	74946499	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	74946499	74946499	G	A	SNP	LRRC53	ENST00000294635	human	ensembl	74_37	-1	novel	missense	c.242	p.T81M	0.004	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC53	HGNC	ENSG00000162621	tier1	-	-	32	0	0.00	12	7	36.84
LRRN3	0	genome.wustl.edu	37	7	110762973	110762973	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	110762973	110762973	G	A	SNP	LRRN3	ENST00000308478	human	ensembl	74_37	+1	known	missense	c.145	p.E49K	1.000	pfam_LRR-contain_N,smart_LRR-contain_N	pfam_Ig_I-set,pfam_Leu-rich_rpt,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_LRR-contain_N,superfamily_Fibronectin_type3,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	LRRN3	HGNC	ENSG00000173114	tier1	-	-	43	0	0.00	36	4	10.00
LY75	0	genome.wustl.edu	37	2	160711447	160711447	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	160711447	160711447	C	T	SNP	LY75	ENST00000554112	human	ensembl	74_37	-1	known	missense	c.2387	p.R796H	0.000	NULL	pfam_C-type_lectin,pfam_FN_type2_col-bd,superfamily_C-type_lectin_fold,superfamily_Ricin_B_lectin,superfamily_Kringle-like,smart_Ricin_B_lectin,smart_FN_type2_col-bd,smart_C-type_lectin,pfscan_FN_type2_col-bd,pfscan_C-type_lectin,pfscan_Ricin_B_lectin	-	no_errors	LY75	HGNC	ENSG00000054219				31	0	0.00	41	4	8.89
MAN2B1	0	genome.wustl.edu	37	19	12768292	12768292	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	12768292	12768292	G	A	SNP	MAN2B1	ENST00000456935	human	ensembl	74_37	-1	known	missense	c.1387	p.R463C	0.530	pfam_Glyco_hydro_38_cen_dom,smart_Glyco_hydro_38_cen_dom	pfam_Glyco_hydro_38_C,pfam_Glyco_hydro_38_N,pfam_Glyco_hydro_38_cen_dom,superfamily_Gal_mutarotase_SF_dom,superfamily_Glyco_hydro/deAcase_b/a-brl,smart_Glyco_hydro_38_cen_dom	-	no_errors	MAN2B1	HGNC	ENSG00000104774	tier1	-	-	29	0	0.00	13	4	23.53
MAP3K11	0	genome.wustl.edu	37	11	65375494	65375494	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	65375494	65375494	C	T	SNP	MAP3K11	ENST00000309100	human	ensembl	74_37	-1	known	missense	c.968	p.R323H	1.000	pirsf_MAPKKK9/10/11,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_MAPKKK9/10/11,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_SH3_2,pfam_SH3_domain,superfamily_Kinase-like_dom,superfamily_SH3_domain,smart_SH3_domain,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_SH3_domain,pfscan_SH3_domain,pfscan_Prot_kinase_dom	-	no_errors	MAP3K11	HGNC	ENSG00000173327	tier1	-	-	33	0	0.00	33	4	10.81
MAP4K2	0	genome.wustl.edu	37	11	64557073	64557073	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	64557073	64557073	G	T	SNP	MAP4K2	ENST00000294066	human	ensembl	74_37	-1	known	missense	c.2399	p.P800H	1.000	smart_Citron	pfam_Prot_kinase_dom,pfam_Citron,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_Citron,pfscan_Prot_kinase_dom	-	no_errors	MAP4K2	HGNC	ENSG00000168067				60	0	0.00	68	4	5.56
MBTD1	0	genome.wustl.edu	37	17	49270349	49270349	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	49270349	49270349	C	G	SNP	MBTD1	ENST00000415868	human	ensembl	74_37	-1	known	missense	c.1484	p.G495A	1.000	smart_Mbt,pfscan_Mbt	pfam_Mbt,smart_Mbt,pfscan_Mbt,pfscan_Znf_FCS	-	no_errors	MBTD1	HGNC	ENSG00000011258	tier1	-	-	23	0	0.00	51	13	20.31
MDC1	0	genome.wustl.edu	37	6	30675997	30675997	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	30675997	30675997	C	T	SNP	MDC1	ENST00000376406	human	ensembl	74_37	-1	known	missense	c.2359	p.G787R	0.000	NULL	pfam_FHA_dom,superfamily_BRCT_dom,superfamily_SMAD_FHA_domain,smart_FHA_dom,pfscan_BRCT_dom,pfscan_FHA_dom	-	no_errors	MDC1	HGNC	ENSG00000137337	tier1	rs148637924	-	100	0	0.00	52	50	48.54
MDH1B	0	genome.wustl.edu	37	2	207613753	207613753	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	207613753	207613753	A	T	SNP	MDH1B	ENST00000374412	human	ensembl	74_37	-1	known	missense	c.1207	p.L403M	0.001	pfam_Lactate/malate_DH_C,superfamily_Lactate_DH/Glyco_Ohase_4_C	pfam_Lactate/malate_DH_C,superfamily_Lactate_DH/Glyco_Ohase_4_C	-	no_errors	MDH1B	HGNC	ENSG00000138400				49	0	0.00	57	4	6.56
MEFV	0	genome.wustl.edu	37	16	3299561	3299561	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	3299561	3299561	C	T	SNP	MEFV	ENST00000219596	human	ensembl	74_37	-1	known	missense	c.1130	p.R377H	0.002	pfam_Znf_B-box,smart_Znf_B-box,pfscan_Znf_B-box	pfam_DAPIN,pfam_SPRY_rcpt,pfam_Znf_B-box,superfamily_ConA-like_lec_gl_sf,superfamily_DEATH-like_dom,smart_Znf_B-box,smart_PRY,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_DAPIN,pfscan_Znf_B-box,prints_Butyrophylin	-	no_errors	MEFV	HGNC	ENSG00000103313	tier1	rs144998416	-	80	0	0.00	40	19	32.20
MEGF6	0	genome.wustl.edu	37	1	3413291	3413291	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	3413291	3413291	C	T	SNP	MEGF6	ENST00000356575	human	ensembl	74_37	-1	known	missense	c.3670	p.G1224R	0.942	superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF_laminin	pfam_EGF_laminin,pfam_EGF-like_Ca-bd_dom,superfamily_Growth_fac_rcpt_N_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_EGF_laminin,pfscan_EG-like_dom,pfscan_EMI_domain	-	no_errors	MEGF6	HGNC	ENSG00000162591	tier1	-	-	35	0	0.00	10	20	66.67
METAP2	0	genome.wustl.edu	37	12	95877035	95877037	+	In_Frame_Del	DEL	AAG	AAG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	AAG	AAG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	95877035	95877037	AAG	-	DEL	METAP2	ENST00000323666	human	ensembl	74_37	+1	known	in_frame_del	c.304_306	p.K105in_frame_del	1.000:1.000:1.000	NULL	pfam_Pept_M24_structural-domain,superfamily_Pept_M24_structural-domain,prints_Pept_M24_MAP,tigrfam_Pept_M24A_MAP2	-	no_errors	METAP2	HGNC	ENSG00000111142	tier1			51	0	0.00	33	2	5.71
MIR3139	0	genome.wustl.edu	37	4	144264666	144264666	+	RNA	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	144264666	144264666	C	T	SNP	MIR3139	ENST00000579145	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	MIR3139	HGNC	ENSG00000265623	tier1	-	-	63	0	0.00	49	19	27.54
MMP16	0	genome.wustl.edu	37	8	89339336	89339336	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	89339336	89339336	C	G	SNP	MMP16	ENST00000286614	human	ensembl	74_37	-1	known	missense	c.100	p.V34L	1.000	pirsf_Pept_M10A_Metazoans	pirsf_Pept_M10A_Metazoans,pfam_Hemopexin-like_repeat,pfam_Pept_M10_metallopeptidase,pfam_Pept_M10A_metallopeptidase_C,pfam_Peptidoglycan-bd-like,superfamily_Hemopexin-like_dom,superfamily_Peptidoglycan-bd-like,smart_Peptidase_Metallo,smart_Hemopexin-like_repeat,prints_Pept_M10A	-	no_errors	MMP16	HGNC	ENSG00000156103	tier1	-	-	41	0	0.00	36	13	26.53
MND1	0	genome.wustl.edu	37	4	154279649	154279649	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	154279649	154279649	C	T	SNP	MND1	ENST00000240488	human	ensembl	74_37	+1	known	missense	c.151	p.L51F	0.996	pfam_Mnd1,pfam_BlaI_family,pirsf_Mnd1	pfam_Mnd1,pfam_BlaI_family,pirsf_Mnd1	-	no_errors	MND1	HGNC	ENSG00000121211	tier1	-	-	37	0	0.00	15	19	55.88
MPHOSPH9	0	genome.wustl.edu	37	12	123637124	123637124	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	123637124	123637124	G	T	SNP	MPHOSPH9	ENST00000302349	human	ensembl	74_37	-1	known	missense	c.3043	p.H1015N	0.006	NULL	superfamily_Prefoldin	-	no_errors	MPHOSPH9	HGNC	ENSG00000051825	tier1	-	-	24	0	0.00	23	4	14.81
MRC2	0	genome.wustl.edu	37	17	60742136	60742136	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	60742136	60742136	G	C	SNP	MRC2	ENST00000303375	human	ensembl	74_37	+1	known	missense	c.346	p.A116P	1.000	superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	pfam_C-type_lectin,pfam_FN_type2_col-bd,pfam_Herpes_UL45-like,superfamily_C-type_lectin_fold,superfamily_Ricin_B_lectin,superfamily_Kringle-like,smart_Ricin_B_lectin,smart_FN_type2_col-bd,smart_C-type_lectin,pfscan_FN_type2_col-bd,pfscan_C-type_lectin,pfscan_Ricin_B_lectin,prints_AntifreezeII	-	no_errors	MRC2	HGNC	ENSG00000011028				24	0	0.00	43	5	10.42
MRPL16	0	genome.wustl.edu	37	11	59574020	59574020	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	59574020	59574020	C	T	SNP	MRPL16	ENST00000300151	human	ensembl	74_37	-1	known	missense	c.556	p.A186T	0.998	pfam_Ribosomal_L10e/L16,superfamily_Ribosomal_L10e/L16	pfam_Ribosomal_L10e/L16,superfamily_Ribosomal_L10e/L16,prints_Ribosomal_L16	-	no_errors	MRPL16	HGNC	ENSG00000166902	tier1	-	-	61	0	0.00	47	11	18.97
MRPL3	0	genome.wustl.edu	37	3	131217123	131217124	+	Splice_Site	INS	-	-	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	131217123	131217124	-	A	INS	MRPL3	ENST00000264995	human	ensembl	74_37	-1	known	splice_site_ins	c.370-3_370-2	e4-2	0.998:0.911	-	-	-	no_errors	MRPL3	HGNC	ENSG00000114686	tier1			46	0	0.00	20	2	9.09
MSH6	0	genome.wustl.edu	37	2	48026147	48026147	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	48026147	48026147	C	T	SNP	MSH6	ENST00000234420	human	ensembl	74_37	+1	known	missense	c.1025	p.A342V	0.996	pirsf_DNA_mismatch_repair_Msh6	pfam_DNA_mismatch_repair_MutS_C,pfam_DNA_mismatch_repair_MutS-lik_N,pfam_DNA_mismatch_repair_MutS_core,pfam_PWWP_dom,pfam_DNA_mismatch_repair_MutS_clamp,pfam_DNA_mmatch_repair_MutS_con_dom,superfamily_DNA_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_DNA_mismatch_repair_MutS_N,superfamily_DNA_mmatch_repair_MutS_con_dom,smart_PWWP_dom,smart_DNA_mismatch_repair_MutS_core,smart_DNA_mismatch_repair_MutS_C,pirsf_DNA_mismatch_repair_Msh6,pfscan_PWWP_dom	-	no_errors	MSH6	HGNC	ENSG00000116062	tier1	-	-	37	0	0.00	50	4	7.41
MTSS1	0	genome.wustl.edu	37	8	125716370	125716370	+	Splice_Site	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	125716370	125716370	C	T	SNP	MTSS1	ENST00000518547	human	ensembl	74_37	-1	known	splice_site	c.134+1	e2+1	1.000	-	-	-	no_errors	MTSS1	HGNC	ENSG00000170873	tier1	-	-	39	0	0.00	13	17	56.67
MYCBP2	0	genome.wustl.edu	37	13	77739439	77739439	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	13	77739439	77739439	A	G	SNP	MYCBP2	ENST00000407578	human	ensembl	74_37	-1	known	missense	c.6428	p.I2143T	1.000	superfamily_ARM-type_fold	pfam_PHR,pfam_Reg_chr_condens,pfam_Filamin/ABP280_repeat-like,superfamily_RCC1/BLIP-II,superfamily_Galactose-bd-like,superfamily_Ig_E-set,superfamily_ARM-type_fold,smart_Znf_RING,pfscan_Filamin/ABP280_repeat-like,pfscan_Znf_RING,pfscan_Reg_chr_condens,prints_Reg_chr_condens	-	no_errors	MYCBP2	HGNC	ENSG00000005810	tier1	-	-	35	0	0.00	54	20	27.03
MYOM1	0	genome.wustl.edu	37	18	3134771	3134771	+	Nonsense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	18	3134771	3134771	G	T	SNP	MYOM1	ENST00000356443	human	ensembl	74_37	-1	known	nonsense	c.2261	p.S754*	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	MYOM1	HGNC	ENSG00000101605				51	0	0.00	48	3	5.88
NAPSA	0	genome.wustl.edu	37	19	50861893	50861893	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	50861893	50861893	C	T	SNP	NAPSA	ENST00000253719	human	ensembl	74_37	-1	known	missense	c.1180	p.A394T	0.295	pfam_Aspartic_peptidase,superfamily_Peptidase_aspartic_dom	pfam_Aspartic_peptidase,superfamily_Peptidase_aspartic_dom,prints_Aspartic_peptidase	-	no_errors	NAPSA	HGNC	ENSG00000131400	tier1	-	-	64	0	0.00	38	38	50.00
NBPF3	0	genome.wustl.edu	37	1	21807427	21807427	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	21807427	21807427	G	T	SNP	NBPF3	ENST00000318249	human	ensembl	74_37	+1	known	missense	c.1386	p.M462I	0.000	NULL	pfam_NBPF_dom	-	no_errors	NBPF3	HGNC	ENSG00000142794				30	0	0.00	25	2	7.41
NCBP1	0	genome.wustl.edu	37	9	100407403	100407403	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	100407403	100407403	G	A	SNP	NCBP1	ENST00000375147	human	ensembl	74_37	+1	known	missense	c.386	p.R129H	1.000	pfam_MIF4G-like_typ-3,superfamily_ARM-type_fold,smart_MIF4G-like_typ-3	pfam_MIF4G-like_typ-2,pfam_MIF4G-like_typ-1,pfam_MIF4G-like_typ-3,superfamily_ARM-type_fold,smart_MIF4G-like_typ-3	-	no_errors	NCBP1	HGNC	ENSG00000136937	tier1	-	-	96	0	0.00	84	5	5.62
NCOA6	0	genome.wustl.edu	37	20	33345407	33345407	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	33345407	33345407	G	A	SNP	NCOA6	ENST00000359003	human	ensembl	74_37	-1	known	nonsense	c.1144	p.Q382*	1.000	NULL	NULL	-	no_errors	NCOA6	HGNC	ENSG00000198646				64	0	0.00	58	4	6.45
NES	0	genome.wustl.edu	37	1	156646866	156646866	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	156646866	156646866	C	T	SNP	NES	ENST00000368223	human	ensembl	74_37	-1	known	missense	c.191	p.R64Q	0.987	pfam_IF	pfam_IF	-	no_errors	NES	HGNC	ENSG00000132688	tier1	-	-	34	0	0.00	24	9	27.27
NFATC4	0	genome.wustl.edu	37	14	24838902	24838902	+	Frame_Shift_Del	DEL	G	G	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	14	24838902	24838902	G	-	DEL	NFATC4	ENST00000413692	human	ensembl	74_37	+1	known	frame_shift_del	c.487	p.G164fs	0.035	NULL	pfam_RHD,pfam_IPT,superfamily_p53-like_TF_DNA-bd,superfamily_Ig_E-set,smart_IPT,pfscan_RHD,prints_NFAT	-	no_errors	NFATC4	HGNC	ENSG00000100968	tier1			18	0	0.00	26	2	7.14
NFATC4	0	genome.wustl.edu	37	14	24841738	24841738	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	14	24841738	24841738	C	T	SNP	NFATC4	ENST00000413692	human	ensembl	74_37	+1	known	missense	c.1477	p.R493W	1.000	pfam_RHD,superfamily_p53-like_TF_DNA-bd,pfscan_RHD	pfam_RHD,pfam_IPT,superfamily_p53-like_TF_DNA-bd,superfamily_Ig_E-set,smart_IPT,pfscan_RHD,prints_NFAT	-	no_errors	NFATC4	HGNC	ENSG00000100968	tier1	-	-	41	0	0.00	31	20	39.22
NIPBL	0	genome.wustl.edu	37	5	37020560	37020560	+	Splice_Site	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	37020560	37020560	G	T	SNP	NIPBL	ENST00000282516	human	ensembl	74_37	+1	known	splice_site	c.5011-1	e25-1	1.000	-	-	-	no_errors	NIPBL	HGNC	ENSG00000164190				59	0	0.00	53	3	5.36
NKX2-4	0	genome.wustl.edu	37	20	21377967	21377967	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	21377967	21377967	T	C	SNP	NKX2-4	ENST00000351817	human	ensembl	74_37	-1	known	missense	c.71	p.Y24C	1.000	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom,prints_Homeobox_metazoa	-	no_errors	NKX2-4	HGNC	ENSG00000125816	tier1	-	-	24	0	0.00	29	17	36.96
NLRP5	0	genome.wustl.edu	37	19	56538278	56538278	+	Splice_Site	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	56538278	56538278	G	T	SNP	NLRP5	ENST00000390649	human	ensembl	74_37	+1	known	splice_site	c.680-1	e7-1	0.001	-	-	-	no_errors	NLRP5	HGNC	ENSG00000171487	tier1	-	-	26	0	0.00	36	4	10.00
NPEPPS	0	genome.wustl.edu	37	17	45608675	45608675	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	45608675	45608675	G	T	SNP	NPEPPS	ENST00000322157	human	ensembl	74_37	+1	known	silent	c.9	p.L3	1.000	NULL	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	NPEPPS	HGNC	ENSG00000141279	tier1	-	-	25	0	0.00	45	10	18.18
NPFFR1	0	genome.wustl.edu	37	10	72015106	72015106	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	10	72015106	72015106	C	T	SNP	NPFFR1	ENST00000277942	human	ensembl	74_37	-1	novel	silent	c.900	p.A300	1.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_NPFF_rcpt_1,prints_NPFF_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	NPFFR1	HGNC	ENSG00000148734	tier1	-	-	13	0	0.00	9	10	52.63
NUMA1	0	genome.wustl.edu	37	11	71718357	71718357	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	71718357	71718357	G	A	SNP	NUMA1	ENST00000393695	human	ensembl	74_37	-1	known	missense	c.5341	p.R1781W	1.000	NULL	superfamily_Prefoldin	-	no_errors	NUMA1	HGNC	ENSG00000137497	tier1	-	-	30	0	0.00	24	11	30.56
ODAM	0	genome.wustl.edu	37	4	71062422	71062422	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	71062422	71062422	G	A	SNP	ODAM	ENST00000396094	human	ensembl	74_37	+1	known	missense	c.65	p.R22H	0.005	NULL	NULL	-	no_errors	ODAM	HGNC	ENSG00000109205	tier1	-	-	58	0	0.00	46	13	22.03
ODF3L2	0	genome.wustl.edu	37	19	464039	464039	+	Silent	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	464039	464039	C	A	SNP	ODF3L2	ENST00000315489	human	ensembl	74_37	-1	known	silent	c.675	p.L225	1.000	pfam_SHIPPO-rpt	pfam_SHIPPO-rpt	-	no_errors	ODF3L2	HGNC	ENSG00000181781	tier1	-	-	33	0	0.00	13	7	35.00
OR10A4	0	genome.wustl.edu	37	11	6898665	6898665	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	6898665	6898665	C	A	SNP	OR10A4	ENST00000379829	human	ensembl	74_37	+1	known	missense	c.787	p.P263T	0.631	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10A4	HGNC	ENSG00000170782	tier1	-	-	27	0	0.00	13	9	40.91
OR10K1	0	genome.wustl.edu	37	1	158435970	158435970	+	Silent	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	158435970	158435970	T	C	SNP	OR10K1	ENST00000289451	human	ensembl	74_37	+1	known	silent	c.619	p.L207	0.211	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10K1	HGNC	ENSG00000173285	tier1	-	-	66	0	0.00	53	12	18.46
OR6B2	0	genome.wustl.edu	37	2	240969167	240969167	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	240969167	240969167	C	T	SNP	OR6B2	ENST00000402971	human	ensembl	74_37	-1	known	missense	c.680	p.R227H	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6B2	HGNC	ENSG00000182083	tier1	-	-	37	0	0.00	36	6	13.95
OR6K6	0	genome.wustl.edu	37	1	158725236	158725236	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	158725236	158725236	C	T	SNP	OR6K6	ENST00000368144	human	ensembl	74_37	+1	known	missense	c.631	p.P211S	0.915	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR6K6	HGNC	ENSG00000180433	tier1	-	-	36	0	0.00	21	8	27.59
OTC	0	genome.wustl.edu	37	X	38268008	38268008	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	X	38268008	38268008	A	T	SNP	OTC	ENST00000039007	human	ensembl	74_37	+1	known	missense	c.677	p.D226V	1.000	pfam_Asp_carbamoyltransf_Asp/Orn-bd,superfamily_Asp/Orn_carbamoylTrfase,tigrfam_Orn/put_carbamltrans	pfam_Asp_carbamoyltransf_Asp/Orn-bd,pfam_Asp/Orn_carbamoyltranf_P-bd,superfamily_Asp/Orn_carbamoylTrfase,prints_Orn/put_carbamltrans,prints_Asp/Orn_carbamoylTrfase,prints_Asp_carbamoyltransf,tigrfam_Orn/put_carbamltrans	-	no_errors	OTC	HGNC	ENSG00000036473	tier1	-	-	89	0	0.00	40	26	39.39
PACS1	0	genome.wustl.edu	37	11	66006623	66006623	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	66006623	66006623	C	T	SNP	PACS1	ENST00000320580	human	ensembl	74_37	+1	known	silent	c.2304	p.D768	0.086	pfam_Phosphofurin_acidic_CS-1	pfam_Phosphofurin_acidic_CS-1	-	no_errors	PACS1	HGNC	ENSG00000175115	tier1	-	-	48	0	0.00	43	17	28.33
PARP8	0	genome.wustl.edu	37	5	49962737	49962738	+	RNA	INS	-	-	CCT			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	49962737	49962738	-	CCT	INS	PARP8	ENST00000513414	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.994:0.991	-	-	-	no_errors	PARP8	HGNC	ENSG00000151883	tier1			33	0	0.00	28	4	12.50
PARVA	0	genome.wustl.edu	37	11	12495472	12495472	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	12495472	12495472	T	C	SNP	PARVA	ENST00000334956	human	ensembl	74_37	+1	known	missense	c.359	p.V120A	0.937	superfamily_CH-domain	pfam_CH-domain,superfamily_CH-domain,smart_CH-domain,pfscan_CH-domain	-	no_errors	PARVA	HGNC	ENSG00000197702				54	0	0.00	61	4	6.15
PAX7	0	genome.wustl.edu	37	1	19029767	19029767	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	19029767	19029767	G	C	SNP	PAX7	ENST00000375375	human	ensembl	74_37	+1	known	missense	c.1132	p.V378L	0.999	pfam_Pax7	pfam_Paired_dom,pfam_Homeobox_dom,pfam_Pax7,superfamily_Homeodomain-like,smart_Paired_dom,smart_Homeobox_dom,prints_Paired_dom,pfscan_Homeobox_dom,pfscan_Paired_dom	-	no_errors	PAX7	HGNC	ENSG00000009709	tier1	-	-	70	0	0.00	63	4	5.97
PCDHA10	0	genome.wustl.edu	37	5	140236457	140236457	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	140236457	140236457	A	T	SNP	PCDHA10	ENST00000307360	human	ensembl	74_37	+1	known	missense	c.824	p.E275V	0.983	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA10	HGNC	ENSG00000250120	tier1	-	-	16	0	0.00	18	7	28.00
PCDHA8	0	genome.wustl.edu	37	5	140222186	140222186	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	140222186	140222186	C	G	SNP	PCDHA8	ENST00000531613	human	ensembl	74_37	+1	known	missense	c.1280	p.A427G	0.951	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA8	HGNC	ENSG00000204962				46	0	0.00	57	6	9.52
PCDHA8	0	genome.wustl.edu	37	5	140222187	140222187	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	140222187	140222187	G	A	SNP	PCDHA8	ENST00000531613	human	ensembl	74_37	+1	known	silent	c.1281	p.A427	0.003	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,prints_Cadherin,pfscan_Cadherin	-	no_errors	PCDHA8	HGNC	ENSG00000204962				45	0	0.00	58	5	7.94
PCDHGA6	0	genome.wustl.edu	37	5	140755355	140755355	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	140755355	140755355	A	T	SNP	PCDHGA6	ENST00000517434	human	ensembl	74_37	+1	known	missense	c.1705	p.T569S	0.622	superfamily_Cadherin-like	pfam_Cadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDHGA6	HGNC	ENSG00000253731	tier1	-	-	126	0	0.00	28	73	72.28
PDE4DIP	0	genome.wustl.edu	37	1	144930759	144930759	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	144930759	144930759	G	T	SNP	PDE4DIP	ENST00000313431	human	ensembl	74_37	-1	known	missense	c.950	p.S317Y	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	PDE4DIP	HGNC	ENSG00000178104	tier1	-	-	81	0	0.00	83	5	5.68
PDE6B	0	genome.wustl.edu	37	4	661763	661765	+	In_Frame_Del	DEL	AGG	AGG	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	AGG	AGG					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	661763	661765	AGG	-	DEL	PDE6B	ENST00000496514	human	ensembl	74_37	+1	known	in_frame_del	c.2471_2473	p.E828in_frame_del	1.000:1.000:1.000	NULL	pfam_PDEase_catalytic_dom,pfam_GAF,smart_GAF,smart_HD/PDEase_dom,prints_PDEase	-	no_errors	PDE6B	HGNC	ENSG00000133256	tier1			23	0	0.00	14	3	17.65
PDZRN3	0	genome.wustl.edu	37	3	73453349	73453349	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	73453349	73453349	C	T	SNP	PDZRN3	ENST00000263666	human	ensembl	74_37	-1	known	silent	c.1116	p.K372	1.000	NULL	pfam_PDZ,pfam_Znf_C3HC4_RING-type,superfamily_PDZ,superfamily_TRAF-like,smart_Znf_RING,smart_PDZ,pfscan_PDZ,pfscan_Znf_RING,pfscan_Znf_TRAF	-	no_errors	PDZRN3	HGNC	ENSG00000121440	tier1	-	-	67	0	0.00	29	17	36.96
PIK3R1	0	genome.wustl.edu	37	5	67522599	67522600	+	In_Frame_Ins	INS	-	-	AAT			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	67522599	67522600	-	AAT	INS	PIK3R1	ENST00000396611	human	ensembl	74_37	+1	known	in_frame_ins	c.96_97	p.33in_frame_insN	1.000:1.000	pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	pfam_SH2,pfam_RhoGAP_dom,pfam_SH3_2,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_Guanylate-bd_C,smart_SH3_domain,smart_RhoGAP_dom,smart_SH2,pfscan_SH2,pfscan_SH3_domain,pfscan_RhoGAP_dom,prints_PI3kinase_P85,prints_SH2	-	no_errors	PIK3R1	HGNC	ENSG00000145675	tier1			89	0	0.00	36	14	28.00
PLIN3	0	genome.wustl.edu	37	19	4839272	4839273	+	Frame_Shift_Del	DEL	GT	GT	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	GT	GT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	4839272	4839273	GT	-	DEL	PLIN3	ENST00000221957	human	ensembl	74_37	-1	known	frame_shift_del	c.1237_1236	p.P413fs	1.000:0.003	pirsf_Perilipin	pfam_Perilipin,pirsf_Perilipin	-	no_errors	PLIN3	HGNC	ENSG00000105355	tier1			83	0	0.00	35	22	38.60
POLD2	0	genome.wustl.edu	37	7	44155474	44155474	+	Silent	SNP	T	T	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	44155474	44155474	T	A	SNP	POLD2	ENST00000406581	human	ensembl	74_37	-1	known	silent	c.1038	p.G346	0.954	pfam_DNA_pol_alpha/epsilon_bsu	pfam_DNA_pol_alpha/epsilon_bsu	-	no_errors	POLD2	HGNC	ENSG00000106628	tier1	-	-	41	0	0.00	22	20	47.62
PRAMEF5	0	genome.wustl.edu	37	1	13365910	13365910	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	13365910	13365910	A	C	SNP	PRAMEF5	ENST00000376168	human	ensembl	74_37	+1	known	missense	c.354	p.E118D	0.028	NULL	NULL	-	no_errors	PRAMEF5	HGNC	ENSG00000204502	tier1	-	-	69	0	0.00	43	17	28.33
PRDM10	0	genome.wustl.edu	37	11	129788514	129788514	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	129788514	129788514	G	A	SNP	PRDM10	ENST00000358825	human	ensembl	74_37	-1	known	missense	c.2146	p.R716C	0.904	NULL	pfam_Znf_C2H2,pfam_Znf_C2H2_jaz,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	PRDM10	HGNC	ENSG00000170325	tier1	-	-	60	0	0.00	58	17	22.67
PRIM2	0	genome.wustl.edu	37	6	57393103	57393103	+	RNA	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	57393103	57393103	T	C	SNP	PRIM2	ENST00000550475	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	PRIM2	HGNC	ENSG00000146143	tier1	-	-	87	0	0.00	68	13	16.05
PSD4	0	genome.wustl.edu	37	2	113940951	113940951	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	113940951	113940951	G	T	SNP	PSD4	ENST00000245796	human	ensembl	74_37	+1	known	missense	c.918	p.L306F	0.028	NULL	pfam_Sec7_dom,pfam_Pleckstrin_homology,superfamily_Sec7_dom,smart_Sec7_dom,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_Sec7_dom,prints_PH_dom-spectrin-type	-	no_errors	PSD4	HGNC	ENSG00000125637	tier1	-	-	36	0	0.00	55	4	6.78
PTPRD	0	genome.wustl.edu	37	9	8500768	8500768	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	8500768	8500768	C	T	SNP	PTPRD	ENST00000356435	human	ensembl	74_37	-1	known	missense	c.2114	p.R705Q	1.000	superfamily_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRD	HGNC	ENSG00000153707				74	0	0.00	45	3	6.25
PTPRD	0	genome.wustl.edu	37	9	8733794	8733794	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	8733794	8733794	C	T	SNP	PTPRD	ENST00000356435	human	ensembl	74_37	-1	known	missense	c.50	p.R17H	0.733	NULL	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,pfam_Ig_I-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRD	HGNC	ENSG00000153707				30	0	0.00	28	2	6.67
PTRH2	0	genome.wustl.edu	37	17	57756899	57756899	+	RNA	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	57756899	57756899	T	C	SNP	PTRH2	ENST00000587935	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.029	-	-	-	no_errors	PTRH2	HGNC	ENSG00000141378	tier1	-	-	34	0	0.00	50	10	16.39
RAD21L1	0	genome.wustl.edu	37	20	1234974	1234974	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	1234974	1234974	G	A	SNP	RAD21L1	ENST00000409241	human	ensembl	74_37	+1	known	missense	c.1544	p.R515Q	0.993	pfam_Rad21/Rec8_C_eu	pfam_Rad21_Rec8_N,pfam_Rad21/Rec8_C_eu	-	no_errors	RAD21L1	HGNC	ENSG00000244588				40	0	0.00	45	4	8.16
RAG2	0	genome.wustl.edu	37	11	36615695	36615695	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	36615695	36615695	G	T	SNP	RAG2	ENST00000311485	human	ensembl	74_37	-1	known	silent	c.24	p.V8	0.058	pfam_RAG2	pfam_RAG2,superfamily_Gal_Oxase/kelch_b-propeller,superfamily_Znf_FYVE_PHD	-	no_errors	RAG2	HGNC	ENSG00000175097				47	0	0.00	28	2	6.67
RANBP6	0	genome.wustl.edu	37	9	6012712	6012712	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	6012712	6012712	C	T	SNP	RANBP6	ENST00000259569	human	ensembl	74_37	-1	known	missense	c.2896	p.A966T	1.000	superfamily_ARM-type_fold	pfam_HEAT,superfamily_ARM-type_fold	-	no_errors	RANBP6	HGNC	ENSG00000137040	tier1	-	-	42	0	0.00	22	3	12.00
RBBP6	0	genome.wustl.edu	37	16	24578657	24578657	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	24578657	24578657	G	T	SNP	RBBP6	ENST00000319715	human	ensembl	74_37	+1	known	missense	c.1783	p.A595S	1.000	NULL	pfam_DWNN_domain,pfam_Ubox_domain,pfam_Znf_CCHC,superfamily_Znf_CCHC,smart_Znf_CCHC,smart_Znf_RING,pfscan_Znf_RING,pfscan_Znf_CCHC	-	no_errors	RBBP6	HGNC	ENSG00000122257				81	0	0.00	70	4	5.41
RDX	0	genome.wustl.edu	37	11	110128868	110128868	+	Missense_Mutation	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	110128868	110128868	T	C	SNP	RDX	ENST00000530749	human	ensembl	74_37	-1	known	missense	c.514	p.I172V	1.000	pirsf_ERM,pfam_FERM_central,superfamily_FERM_central,smart_Band_41_domain,prints_Ez/rad/moesin_like,pfscan_FERM_domain	pirsf_ERM,pfam_ERM_C_dom,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,superfamily_Moesin_tail,superfamily_Adenylate_cyclase-assoc_CAP_N,smart_Band_41_domain,prints_Ez/rad/moesin_like,prints_Band_41_fam,pfscan_FERM_domain	-	no_errors	RDX	HGNC	ENSG00000137710				29	0	0.00	32	3	8.57
RELN	0	genome.wustl.edu	37	7	103138602	103138602	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	103138602	103138602	G	A	SNP	RELN	ENST00000424685	human	ensembl	74_37	-1	known	missense	c.8765	p.A2922V	0.997	superfamily_Sialidases	pfam_EGF_extracell,pfam_Reeler_dom,pfam_BNR_rpt,superfamily_Sialidases,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,pfscan_EG-like_dom,pfscan_Reeler_dom	-	no_errors	RELN	HGNC	ENSG00000189056	tier1	-	-	53	0	0.00	66	4	5.71
RGS21	0	genome.wustl.edu	37	1	192321288	192321288	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	192321288	192321288	C	T	SNP	RGS21	ENST00000417209	human	ensembl	74_37	+1	known	missense	c.200	p.A67V	0.995	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS21	HGNC	ENSG00000253148				41	0	0.00	48	3	5.88
RNF165	0	genome.wustl.edu	37	18	44036483	44036483	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	18	44036483	44036483	C	T	SNP	RNF165	ENST00000269439	human	ensembl	74_37	+1	known	missense	c.925	p.R309C	1.000	pfam_Znf_C3HC4_RING-type,smart_Znf_RING-CH,smart_Znf_RING,pfscan_Znf_RING	pfam_Znf_C3HC4_RING-type,smart_Znf_RING-CH,smart_Znf_RING,pfscan_Znf_RING	-	no_errors	RNF165	HGNC	ENSG00000141622				32	0	0.00	11	7	38.89
RNF214	0	genome.wustl.edu	37	11	117152314	117152314	+	Splice_Site	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	11	117152314	117152314	A	T	SNP	RNF214	ENST00000300650	human	ensembl	74_37	+1	known	splice_site	c.1237-2	e9-2	0.989	-	-	-	no_errors	RNF214	HGNC	ENSG00000167257				41	0	0.00	33	2	5.56
RNFT2	0	genome.wustl.edu	37	12	117289549	117289549	+	Frame_Shift_Del	DEL	A	A	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	117289549	117289549	A	-	DEL	RNFT2	ENST00000319176	human	ensembl	74_37	+1	putative	frame_shift_del	c.766	p.K259fs	0.003	NULL	NULL	-	no_errors	RNFT2	HGNC	ENSG00000135119	tier1			24	0	0.00	21	2	8.70
ROBO1	0	genome.wustl.edu	37	3	78689016	78689016	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	3	78689016	78689016	G	A	SNP	ROBO1	ENST00000464233	human	ensembl	74_37	-1	known	missense	c.2915	p.A972V	0.253	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	ROBO1	HGNC	ENSG00000169855	tier1	-	-	24	0	0.00	14	4	22.22
RPS5	0	genome.wustl.edu	37	19	58904526	58904526	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	58904526	58904526	G	A	SNP	RPS5	ENST00000196551	human	ensembl	74_37	+1	known	missense	c.292	p.E98K	1.000	pfam_Ribosomal_S7_dom,superfamily_Ribosomal_S7_dom,tigrfam_Ribosomal_S5/S7_euk/arc	pfam_Ribosomal_S7_dom,superfamily_Ribosomal_S7_dom,tigrfam_Ribosomal_S5/S7_euk/arc	-	no_errors	RPS5	HGNC	ENSG00000083845				40	0	0.00	38	2	5.00
RPS8	0	genome.wustl.edu	37	1	45243860	45243860	+	RNA	DEL	T	T	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	45243860	45243860	T	-	DEL	RPS8	ENST00000484599	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RPS8	HGNC	ENSG00000142937	tier1			26	0	0.00	19	2	9.52
SAMD9L	0	genome.wustl.edu	37	7	92762790	92762791	+	Frame_Shift_Ins	INS	-	-	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	92762790	92762791	-	T	INS	SAMD9L	ENST00000318238	human	ensembl	74_37	-1	known	frame_shift_ins	c.2495_2494	p.T832fs	0.170:0.145	superfamily_P-loop_NTPase	superfamily_SAM/pointed,superfamily_P-loop_NTPase,pfscan_SAM	-	no_errors	SAMD9L	HGNC	ENSG00000177409	tier1			57	0	0.00	47	23	32.86
SASH1	0	genome.wustl.edu	37	6	148792635	148792635	+	Silent	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	148792635	148792635	A	C	SNP	SASH1	ENST00000367467	human	ensembl	74_37	+1	known	silent	c.510	p.S170	0.999	NULL	pfam_rSAM/SH3_domain-containing,pfam_SAM_2,pfam_SAM_type1,pfam_SH3_2,superfamily_SAM/pointed,superfamily_SH3_domain,smart_SH3_domain,smart_SAM,pfscan_SAM	-	no_errors	SASH1	HGNC	ENSG00000111961	tier1	-	-	73	0	0.00	47	23	32.86
SCN9A	0	genome.wustl.edu	37	2	167084183	167084183	+	Silent	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	167084183	167084183	A	G	SNP	SCN9A	ENST00000303354	human	ensembl	74_37	-1	known	silent	c.4260	p.V1420	0.769	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,smart_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN9A	HGNC	ENSG00000169432	tier1	-	-	47	0	0.00	28	28	50.00
SCNM1	0	genome.wustl.edu	37	1	151139677	151139677	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	151139677	151139677	G	A	SNP	SCNM1	ENST00000368905	human	ensembl	74_37	+1	known	missense	c.292	p.E98K	0.367	NULL	NULL	-	no_errors	SCNM1	HGNC	ENSG00000163156	tier1	-	-	35	0	0.00	31	8	20.51
SLC14A1	0	genome.wustl.edu	37	18	43329755	43329755	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	18	43329755	43329755	G	T	SNP	SLC14A1	ENST00000415427	human	ensembl	74_37	+1	known	missense	c.1177	p.A393S	0.383	pfam_Urea_transporter	pfam_Urea_transporter	-	no_errors	SLC14A1	HGNC	ENSG00000141469				51	0	0.00	32	3	8.57
SLC16A1	0	genome.wustl.edu	37	1	113464612	113464612	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	113464612	113464612	C	T	SNP	SLC16A1	ENST00000369626	human	ensembl	74_37	-1	known	missense	c.361	p.G121S	1.000	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt	-	no_errors	SLC16A1	HGNC	ENSG00000155380	tier1	-	-	37	0	0.00	27	3	10.00
SLC16A2	0	genome.wustl.edu	37	X	73751298	73751298	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	X	73751298	73751298	A	T	SNP	SLC16A2	ENST00000276033	human	ensembl	74_37	+1	known	missense	c.1752	p.R584S	0.985	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC16A2	HGNC	ENSG00000147100	tier1	-	-	27	0	0.00	21	4	16.00
SLC22A2	0	genome.wustl.edu	37	6	160677677	160677677	+	Missense_Mutation	SNP	C	C	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	160677677	160677677	C	G	SNP	SLC22A2	ENST00000366953	human	ensembl	74_37	-1	known	missense	c.487	p.G163R	0.990	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Orgcat_transp	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Orgcat_transp	-	no_errors	SLC22A2	HGNC	ENSG00000112499				48	0	0.00	32	2	5.88
SLC4A8	0	genome.wustl.edu	37	12	51845973	51845973	+	Nonsense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	51845973	51845973	G	T	SNP	SLC4A8	ENST00000453097	human	ensembl	74_37	+1	known	nonsense	c.343	p.E115*	1.000	superfamily_PTrfase/Anion_transptr	pfam_HCO3_transpt_C,pfam_Band3_cytoplasmic_dom,superfamily_PTrfase/Anion_transptr,prints_HCO3_transpt_euk,prints_Na/HCO3_transpt,tigrfam_HCO3_transpt_euk	-	no_errors	SLC4A8	HGNC	ENSG00000050438				40	0	0.00	40	3	6.98
SLC5A11	0	genome.wustl.edu	37	16	24921729	24921729	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	24921729	24921729	C	T	SNP	SLC5A11	ENST00000347898	human	ensembl	74_37	+1	known	missense	c.1753	p.P585S	0.000	NULL	pfam_Na/solute_symporter,pfscan_Na/solute_symporter,tigrfam_Na/solute_symporter_subgr	-	no_errors	SLC5A11	HGNC	ENSG00000158865				53	0	0.00	45	3	6.25
SLCO3A1	0	genome.wustl.edu	37	15	92706461	92706462	+	RNA	DEL	AC	AC	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	AC	AC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	92706461	92706462	AC	-	DEL	SLCO3A1	ENST00000555549	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	SLCO3A1	HGNC	ENSG00000176463	tier1			37	0	0.00	24	2	7.69
SNAP25	0	genome.wustl.edu	37	20	10287918	10287918	+	RNA	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	20	10287918	10287918	A	T	SNP	SNAP25	ENST00000495883	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SNAP25	HGNC	ENSG00000132639	tier1	-	-	69	0	0.00	50	12	19.35
SNAPIN	0	genome.wustl.edu	37	1	153631933	153631933	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	153631933	153631933	G	T	SNP	SNAPIN	ENST00000368685	human	ensembl	74_37	+1	known	missense	c.200	p.R67L	0.990	pirsf_Snapin	pirsf_Snapin	-	no_errors	SNAPIN	HGNC	ENSG00000143553				32	0	0.00	38	3	7.32
SPAG17	0	genome.wustl.edu	37	1	118539321	118539321	+	Missense_Mutation	SNP	A	A	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	118539321	118539321	A	T	SNP	SPAG17	ENST00000336338	human	ensembl	74_37	-1	known	missense	c.4822	p.L1608M	0.000	NULL	NULL	-	no_errors	SPAG17	HGNC	ENSG00000155761	tier1	-	-	26	0	0.00	9	10	52.63
SPATA31D1	0	genome.wustl.edu	37	9	84608742	84608742	+	Missense_Mutation	SNP	A	A	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	84608742	84608742	A	C	SNP	SPATA31D1	ENST00000344803	human	ensembl	74_37	+1	known	missense	c.3357	p.Q1119H	0.001	NULL	NULL	-	no_errors	SPATA31D1	HGNC	ENSG00000214929	tier1	-	-	44	0	0.00	39	13	25.00
SPTA1	0	genome.wustl.edu	37	1	158618411	158618411	+	Missense_Mutation	SNP	T	T	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	158618411	158618411	T	A	SNP	SPTA1	ENST00000368147	human	ensembl	74_37	-1	known	missense	c.3602	p.K1201M	1.000	pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin	pfam_Spectrin_repeat,pfam_EF-hand_Ca_insen,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_Spectrin/alpha-actinin,smart_SH3_domain,pfscan_EF_hand_dom,pfscan_SH3_domain,prints_Spectrin_alpha_SH3	-	no_errors	SPTA1	HGNC	ENSG00000163554	tier1	-	-	23	0	0.00	28	4	12.50
SRP68	0	genome.wustl.edu	37	17	74036995	74036995	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	74036995	74036995	G	A	SNP	SRP68	ENST00000307877	human	ensembl	74_37	-1	known	missense	c.1589	p.A530V	1.000	NULL	NULL	-	no_errors	SRP68	HGNC	ENSG00000167881				59	0	0.00	58	4	6.45
STAB2	0	genome.wustl.edu	37	12	104111582	104111582	+	Missense_Mutation	SNP	A	A	G			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	104111582	104111582	A	G	SNP	STAB2	ENST00000388887	human	ensembl	74_37	+1	known	missense	c.4646	p.D1549G	0.983	smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pfam_FAS1_domain,pfam_Link,superfamily_C-type_lectin_fold,superfamily_FAS1_domain,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF_laminin,smart_EGF-like_Ca-bd_dom,smart_FAS1_domain,smart_Link,pfscan_EG-like_dom,pfscan_FAS1_domain,pfscan_Link	-	no_errors	STAB2	HGNC	ENSG00000136011	tier1	-	-	54	0	0.00	43	16	27.12
STAT3	0	genome.wustl.edu	37	17	40491335	40491335	+	Silent	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	40491335	40491335	C	A	SNP	STAT3	ENST00000264657	human	ensembl	74_37	-1	known	silent	c.465	p.V155	0.757	pfam_STAT_TF_alpha,superfamily_STAT_TF_coiled-coil	pfam_STAT_TF_DNA-bd,pfam_STAT_TF_alpha,pfam_STAT_TF_prot_interaction,pfam_SH2,superfamily_p53-like_TF_DNA-bd,superfamily_STAT_TF_coiled-coil,superfamily_STAT_TF_prot_interaction,smart_STAT_TF_prot_interaction,pfscan_SH2	-	no_errors	STAT3	HGNC	ENSG00000168610	tier1	-	-	22	0	0.00	50	14	21.88
TARS2	0	genome.wustl.edu	37	1	150463878	150463878	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	150463878	150463878	G	T	SNP	TARS2	ENST00000369064	human	ensembl	74_37	+1	known	missense	c.521	p.R174L	0.070	superfamily_Thr/Ala-tRNA-synth_IIc_edit,tigrfam_Thr-tRNA-ligase_IIa	pfam_aa-tRNA-synt_IIb_cons-dom,pfam_Anticodon-bd,pfam_TGS,pfam_tRNA_SAD,superfamily_Thr/Ala-tRNA-synth_IIc_edit,superfamily_Anticodon-bd,superfamily_TGS-like,smart_tRNA_SAD,pfscan_aa-tRNA-synth_II,prints_Thr-tRNA-ligase_IIa,tigrfam_Thr-tRNA-ligase_IIa	-	no_errors	TARS2	HGNC	ENSG00000143374	tier1	-	-	43	0	0.00	55	4	6.78
TBC1D29	0	genome.wustl.edu	37	17	28887667	28887667	+	Silent	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	28887667	28887667	T	C	SNP	TBC1D29	ENST00000579181	human	ensembl	74_37	+1	known	silent	c.111	p.D37	1.000	superfamily_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	superfamily_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D29	HGNC	ENSG00000266733	tier1	rs78888987	-	79	0	0.00	62	6	8.82
TBX19	0	genome.wustl.edu	37	1	168269680	168269680	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	168269680	168269680	C	T	SNP	TBX19	ENST00000367821	human	ensembl	74_37	+1	known	missense	c.686	p.P229L	0.001	NULL	pfam_TF_T-box,superfamily_p53-like_TF_DNA-bd,smart_TF_T-box,pfscan_TF_T-box,prints_TF_T-box,prints_TF_Brachyury	-	no_errors	TBX19	HGNC	ENSG00000143178	tier1	-	-	35	0	0.00	35	10	22.22
TCTEX1D4	0	genome.wustl.edu	37	1	45272226	45272226	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	45272226	45272226	G	A	SNP	TCTEX1D4	ENST00000339355	human	ensembl	74_37	-1	known	nonsense	c.115	p.R39*	0.002	NULL	pfam_Tctex	-	no_errors	TCTEX1D4	HGNC	ENSG00000188396	tier1	-	-	31	0	0.00	22	10	31.25
TDP2	0	genome.wustl.edu	37	6	24666321	24666321	+	RNA	DEL	A	A	-			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	6	24666321	24666321	A	-	DEL	TDP2	ENST00000480495	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	TDP2	HGNC	ENSG00000111802	tier1			43	0	0.00	42	4	8.70
TEX15	0	genome.wustl.edu	37	8	30694786	30694786	+	Nonsense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	30694786	30694786	G	T	SNP	TEX15	ENST00000256246	human	ensembl	74_37	-1	known	nonsense	c.7865	p.S2622*	0.001	NULL	NULL	-	no_errors	TEX15	HGNC	ENSG00000133863				46	0	0.00	36	2	5.26
TMEM194A	0	genome.wustl.edu	37	12	57456971	57456971	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	57456971	57456971	G	A	SNP	TMEM194A	ENST00000300128	human	ensembl	74_37	-1	known	missense	c.911	p.A304V	0.998	pfam_TMEM194	pfam_TMEM194	-	no_errors	TMEM194A	HGNC	ENSG00000166881	tier1	-	-	48	0	0.00	29	27	48.21
TMEM67	0	genome.wustl.edu	37	8	94792886	94792886	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	8	94792886	94792886	C	T	SNP	TMEM67	ENST00000453321	human	ensembl	74_37	+1	known	silent	c.780	p.Y260	0.034	pfam_Meckelin	pfam_Meckelin,superfamily_Growth_fac_rcpt_N_dom	-	no_errors	TMEM67	HGNC	ENSG00000164953	tier1	-	-	50	0	0.00	56	30	34.88
TMOD2	0	genome.wustl.edu	37	15	52075011	52075011	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	15	52075011	52075011	G	A	SNP	TMOD2	ENST00000249700	human	ensembl	74_37	+1	known	missense	c.718	p.D240N	1.000	NULL	pfam_Tropomodulin	-	no_errors	TMOD2	HGNC	ENSG00000128872				32	0	0.00	33	3	8.33
TMPRSS11B	0	genome.wustl.edu	37	4	69094484	69094484	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	4	69094484	69094484	C	T	SNP	TMPRSS11B	ENST00000332644	human	ensembl	74_37	-1	known	missense	c.1065	p.M355I	0.333	pfam_Peptidase_S1,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pirsf_Pept_S1A_HAT/DESC1,pfscan_Peptidase_S1	pfam_Peptidase_S1,pfam_SEA_dom,superfamily_Trypsin-like_Pept_dom,smart_Peptidase_S1,pirsf_Pept_S1A_HAT/DESC1,pfscan_SEA_dom,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	TMPRSS11B	HGNC	ENSG00000185873	tier1	-	-	33	0	0.00	10	7	41.18
TNR	0	genome.wustl.edu	37	1	175372433	175372433	+	Silent	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	1	175372433	175372433	C	T	SNP	TNR	ENST00000263525	human	ensembl	74_37	-1	known	silent	c.819	p.K273	1.000	pfam_EGF_extracell,smart_EG-like_dom	pfam_Fibronectin_type3,pfam_Fibrinogen_a/b/g_C_dom,pfam_EGF_extracell,superfamily_Fibrinogen_a/b/g_C_dom,superfamily_Fibronectin_type3,smart_EG-like_dom,smart_Fibronectin_type3,smart_Fibrinogen_a/b/g_C_dom,pfscan_Fibronectin_type3	-	no_errors	TNR	HGNC	ENSG00000116147	tier1	-	-	34	0	0.00	26	12	31.58
TNS1	0	genome.wustl.edu	37	2	218700896	218700896	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	218700896	218700896	C	A	SNP	TNS1	ENST00000171887	human	ensembl	74_37	-1	known	missense	c.2671	p.A891S	0.997	NULL	pfam_PTB,pfam_Tensin_phosphatase_C2-dom,pfam_SH2,superfamily_C2_dom,smart_Tyr_Pase_cat,smart_SH2,smart_PTB/PI_dom,pfscan_SH2,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	TNS1	HGNC	ENSG00000079308	tier1	-	-	73	0	0.00	71	22	23.40
TP53	0	genome.wustl.edu	37	17	7577539	7577539	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	7577539	7577539	G	A	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.742	p.R248W	1.000	pfam_p53_DNA-bd,superfamily_p53-like_TF_DNA-bd,prints_p53_tumour_suppressor	pfam_p53_DNA-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_DNA-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	rs121912651	-	50	0	0.00	8	14	63.64
TPST1	0	genome.wustl.edu	37	7	65705856	65705856	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	7	65705856	65705856	G	A	SNP	TPST1	ENST00000304842	human	ensembl	74_37	+1	known	silent	c.444	p.K148	1.000	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	pfam_Sulfotransferase_dom,superfamily_P-loop_NTPase	-	no_errors	TPST1	HGNC	ENSG00000169902				35	0	0.00	27	2	6.90
TRIP10	0	genome.wustl.edu	37	19	6743720	6743720	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	6743720	6743720	C	T	SNP	TRIP10	ENST00000313244	human	ensembl	74_37	+1	known	missense	c.515	p.A172V	1.000	NULL	pfam_FCH_dom,pfam_SH3_domain,superfamily_SH3_domain,smart_FCH_dom,smart_SH3_domain,pfscan_FCH_dom,pfscan_SH3_domain	-	no_errors	TRIP10	HGNC	ENSG00000125733				76	0	0.00	51	4	7.27
TRPM3	0	genome.wustl.edu	37	9	73225653	73225653	+	Nonsense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	9	73225653	73225653	G	A	SNP	TRPM3	ENST00000423814	human	ensembl	74_37	-1	known	nonsense	c.2584	p.R862*	0.949	NULL	pfam_Ion_trans_dom	-	no_errors	TRPM3	HGNC	ENSG00000083067	tier1	-	-	66	0	0.00	75	17	18.48
TRPV2	0	genome.wustl.edu	37	17	16329551	16329551	+	Missense_Mutation	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	16329551	16329551	C	A	SNP	TRPV2	ENST00000338560	human	ensembl	74_37	+1	known	missense	c.1063	p.L355M	1.000	tigrfam_TRP_channel	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_TRPV1-4_channel,tigrfam_TRP_channel	-	no_errors	TRPV2	HGNC	ENSG00000187688	tier1	-	-	49	0	0.00	33	12	26.67
TSHZ3	0	genome.wustl.edu	37	19	31768189	31768189	+	Missense_Mutation	SNP	G	G	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	31768189	31768189	G	C	SNP	TSHZ3	ENST00000240587	human	ensembl	74_37	-1	known	missense	c.2510	p.S837W	1.000	NULL	superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	TSHZ3	HGNC	ENSG00000121297	tier1	-	-	27	0	0.00	19	12	38.71
TTC28-AS1	0	genome.wustl.edu	37	22	28388568	28388568	+	RNA	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	22	28388568	28388568	G	T	SNP	TTC28-AS1	ENST00000428584	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TTC28-AS1	HGNC	ENSG00000235954	tier1	-	-	48	0	0.00	35	24	40.68
TTN	0	genome.wustl.edu	37	2	179428956	179428956	+	Silent	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	179428956	179428956	G	A	SNP	TTN	ENST00000342992	human	ensembl	74_37	-1	known	silent	c.74199	p.G24733	1.000	pfam_Ig_I-set,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	TTN	HGNC	ENSG00000155657	tier1	-	-	40	0	0.00	33	4	10.81
UBE2O	0	genome.wustl.edu	37	17	74388061	74388061	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	74388061	74388061	C	T	SNP	UBE2O	ENST00000319380	human	ensembl	74_37	-1	known	missense	c.3080	p.G1027D	1.000	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	pfam_UBQ-conjugat_E2,superfamily_UBQ-conjugating_enzyme/RWD,pfscan_UBQ-conjugat_E2	-	no_errors	UBE2O	HGNC	ENSG00000175931	tier1	-	-	59	0	0.00	71	4	5.33
USP32P2	0	genome.wustl.edu	37	17	18417905	18417905	+	RNA	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	17	18417905	18417905	C	T	SNP	USP32P2	ENST00000412260	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	USP32P2	HGNC	ENSG00000233327	tier1	-	-	110	0	0.00	98	19	16.24
WNT7B	0	genome.wustl.edu	37	22	46345866	46345866	+	Missense_Mutation	SNP	G	G	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	22	46345866	46345866	G	A	SNP	WNT7B	ENST00000339464	human	ensembl	74_37	-1	known	missense	c.232	p.R78C	1.000	pfam_Wnt,smart_Wnt	pfam_Wnt,smart_Wnt,prints_Wnt,prints_Wnt7	-	no_errors	WNT7B	HGNC	ENSG00000188064	tier1	-	-	45	0	0.00	29	12	28.57
XRCC6BP1	0	genome.wustl.edu	37	12	58335569	58335569	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	12	58335569	58335569	C	T	SNP	XRCC6BP1	ENST00000300145	human	ensembl	74_37	+1	known	missense	c.85	p.P29S	1.000	NULL	pfam_Peptidase_M76_ATP23	-	no_errors	XRCC6BP1	HGNC	ENSG00000166896	tier1	-	-	89	0	0.00	60	24	28.57
YTHDC2	0	genome.wustl.edu	37	5	112903395	112903395	+	Silent	SNP	C	C	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	112903395	112903395	C	A	SNP	YTHDC2	ENST00000161863	human	ensembl	74_37	+1	known	silent	c.3093	p.P1031	1.000	pfam_DUF1605	pfam_YTH_domain,pfam_Helicase-assoc_dom,pfam_Helicase_C,pfam_DNA/RNA_helicase_DEAD/DEAH_N,pfam_DUF1605,pfam_R3H_ss-bd,superfamily_P-loop_NTPase,superfamily_Ankyrin_rpt-contain_dom,smart_R3H_ss-bd,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Helicase-assoc_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_R3H_ss-bd,pfscan_YTH_domain,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	YTHDC2	HGNC	ENSG00000047188				28	0	0.00	32	2	5.88
ZNF25	0	genome.wustl.edu	37	10	38246038	38246038	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	10	38246038	38246038	G	T	SNP	ZNF25	ENST00000302609	human	ensembl	74_37	-1	known	missense	c.148	p.H50N	0.000	superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF25	HGNC	ENSG00000175395				43	0	0.00	35	2	5.41
ZNF562	0	genome.wustl.edu	37	19	9763755	9763755	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	9763755	9763755	G	T	SNP	ZNF562	ENST00000448622	human	ensembl	74_37	-1	known	missense	c.1151	p.S384Y	0.000	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF562	HGNC	ENSG00000171466				92	0	0.00	40	4	9.09
ZNF608	0	genome.wustl.edu	37	5	123972613	123972614	+	RNA	INS	-	-	A			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	5	123972613	123972614	-	A	INS	ZNF608	ENST00000513985	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.291:0.200	-	-	-	no_errors	ZNF608	HGNC	ENSG00000168916	tier1			23	0	0.00	10	2	16.67
ZNF615	0	genome.wustl.edu	37	19	52497000	52497000	+	Silent	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	19	52497000	52497000	G	T	SNP	ZNF615	ENST00000594083	human	ensembl	74_37	-1	known	silent	c.1362	p.L454	0.010	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF615	HGNC	ENSG00000197619	tier1	-	-	59	0	0.00	30	13	30.23
ZNF638	0	genome.wustl.edu	37	2	71650383	71650383	+	Missense_Mutation	SNP	G	G	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	71650383	71650383	G	T	SNP	ZNF638	ENST00000264447	human	ensembl	74_37	+1	known	missense	c.3739	p.A1247S	0.998	NULL	pfam_RRM_dom,smart_Znf_U1,smart_Znf_C2H2-like,smart_RRM_dom,pfscan_Znf_C2H2_matrin,pfscan_RRM_dom	-	no_errors	ZNF638	HGNC	ENSG00000075292	tier1	-	-	41	0	0.00	45	4	8.16
ZNF668	0	genome.wustl.edu	37	16	31075398	31075398	+	Missense_Mutation	SNP	C	C	T			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	16	31075398	31075398	C	T	SNP	ZNF668	ENST00000426488	human	ensembl	74_37	-1	known	missense	c.452	p.R151H	0.994	smart_Znf_C2H2-like,pfscan_Znf_C2H2	pfam_Znf_C2H2,smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	ZNF668	HGNC	ENSG00000167394				28	0	0.00	23	5	17.86
ZNF804A	0	genome.wustl.edu	37	2	185803171	185803171	+	Silent	SNP	T	T	C			TCGA-VR-AA4D-01A-11D-A37C-09	TCGA-VR-AA4D-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	877fae34-7fbe-4e7b-8ada-ac5c7f4ab2a5	0802d748-b6aa-4262-a6fe-e6c0dc5161a6	2	185803171	185803171	T	C	SNP	ZNF804A	ENST00000302277	human	ensembl	74_37	+1	known	silent	c.3048	p.T1016	0.532	NULL	pfam_Znf_C2H2_jaz	-	no_errors	ZNF804A	HGNC	ENSG00000170396	tier1	-	-	27	0	0.00	23	15	39.47
