Correlation between copy number variation genes (focal events) and selected clinical features
Uterine Corpus Endometrioid Carcinoma (Primary solid tumor)
23 September 2013  |  analyses__2013_09_23
Maintainer Information
Citation Information
doi:10.7908/C1HT2MP5
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): Correlation between copy number variation genes (focal events) and selected clinical features. Broad Institute of MIT and Harvard. doi:10.7908/C1HT2MP5
Overview
Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 98 focal events and 5 clinical features across 470 patients, 164 significant findings detected with Q value < 0.25.

  • AMP PEAK 1(1P35.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 2(1P34.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 4(1Q21.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 5(1Q22) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 7(2P24.3) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 8(2Q13) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 9(3P25.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 10(3P14.1) MUTATION ANALYSIS cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 11(3Q26.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 12(3Q26.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 13(4P16.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 14(5P15.33) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 15(5Q35.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 16(6P24.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 17(6Q25.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 18(7Q22.1) MUTATION ANALYSIS cnv correlated to 'Time to Death'.

  • AMP PEAK 19(8P11.21) MUTATION ANALYSIS cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 20(8Q24.21) MUTATION ANALYSIS cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 21(8Q24.21) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 22(9P24.2) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 23(9Q34.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 25(11P11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 26(11Q13.2) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 27(11Q14.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 28(12P12.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 29(12Q13.11) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 30(12Q13.2) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 31(13Q34) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 32(14Q24.3) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 33(15Q26.3) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 34(16P11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 35(17Q11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 36(17Q12) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 37(17Q25.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 38(18P11.31) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 39(18Q11.2) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 40(19P13.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 41(19P13.11) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 42(19Q12) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 43(20P13) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 44(20Q11.21) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 45(20Q13.12) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 46(20Q13.33) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • AMP PEAK 47(22Q12.2) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE' and 'COMPLETENESS.OF.RESECTION'.

  • DEL PEAK 1(1P36.11) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 3(2Q22.1) MUTATION ANALYSIS cnv correlated to 'Time to Death' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 4(2Q37.3) MUTATION ANALYSIS cnv correlated to 'AGE'.

  • DEL PEAK 5(3P14.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 6(3Q13.31) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 7(4P16.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 8(4P15.31) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 9(4Q22.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 10(4Q34.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 11(5Q11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 12(6Q26) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 13(7P22.3) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 14(7Q11.22) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 15(7Q31.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 16(7Q36.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 17(8P23.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 18(8P21.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 19(9P23) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 20(9Q21.2) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 21(9Q34.11) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 22(10Q23.31) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 23(11P15.5) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 24(11Q14.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 25(11Q25) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 26(12Q23.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 27(12Q24.33) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 28(13Q11) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 29(13Q14.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 30(14Q13.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 31(15Q15.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 32(15Q23) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 33(16P13.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 34(16Q21) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 35(16Q23.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 36(17P13.3) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 37(17P11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 38(17P11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 39(17Q11.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 40(17Q21.2) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 41(18Q23) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 42(19P13.3) MUTATION ANALYSIS cnv correlated to 'Time to Death',  'AGE', and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 43(19P12) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 44(19Q13.43) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 46(22Q12.1) MUTATION ANALYSIS cnv correlated to 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 47(22Q13.31) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 48(22Q13.32) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

  • DEL PEAK 49(XP21.1) MUTATION ANALYSIS cnv correlated to 'AGE' and 'HISTOLOGICAL.TYPE'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 98 focal events and 5 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 164 significant findings detected.

Clinical
Features 		Time
to
Death 		AGE HISTOLOGICAL
TYPE 		RADIATIONS
RADIATION
REGIMENINDICATION 		COMPLETENESS
OF
RESECTION
nCNV (%) nWild-Type logrank test t-test Fisher's exact test Fisher's exact test Fisher's exact test
AMP PEAK 32(14Q24 3) MUTATION ANALYSIS 54 (11%) 416 0.000704
(0.231) 		0.000179
(0.0629) 		8.71e-13
(3.79e-10) 		0.0811
(1.00) 		0.74
(1.00)
AMP PEAK 36(17Q12) MUTATION ANALYSIS 62 (13%) 408 0.000339
(0.116) 		4.66e-05
(0.017) 		1.19e-19
(5.5e-17) 		1
(1.00) 		0.115
(1.00)
AMP PEAK 42(19Q12) MUTATION ANALYSIS 94 (20%) 376 0.000294
(0.101) 		2.62e-09
(1.08e-06) 		2.16e-38
(1.05e-35) 		0.372
(1.00) 		0.225
(1.00)
AMP PEAK 44(20Q11 21) MUTATION ANALYSIS 118 (25%) 352 0.000368
(0.126) 		6.22e-08
(2.47e-05) 		5.04e-25
(2.41e-22) 		0.0453
(1.00) 		0.0386
(1.00)
DEL PEAK 13(7P22 3) MUTATION ANALYSIS 64 (14%) 406 0.000434
(0.147) 		6.1e-05
(0.022) 		1.18e-14
(5.16e-12) 		0.373
(1.00) 		0.172
(1.00)
DEL PEAK 20(9Q21 2) MUTATION ANALYSIS 104 (22%) 366 0.000763
(0.25) 		3.62e-11
(1.53e-08) 		3.28e-20
(1.53e-17) 		0.269
(1.00) 		0.188
(1.00)
DEL PEAK 42(19P13 3) MUTATION ANALYSIS 131 (28%) 339 3.7e-05
(0.0135) 		7.8e-12
(3.35e-09) 		1.91e-54
(9.35e-52) 		0.141
(1.00) 		0.00351
(0.999)
AMP PEAK 1(1P35 2) MUTATION ANALYSIS 47 (10%) 423 0.125
(1.00) 		0.000674
(0.223) 		1.46e-11
(6.24e-09) 		1
(1.00) 		0.927
(1.00)
AMP PEAK 2(1P34 2) MUTATION ANALYSIS 59 (13%) 411 0.0564
(1.00) 		0.000435
(0.147) 		1.38e-16
(6.17e-14) 		0.282
(1.00) 		0.0608
(1.00)
AMP PEAK 4(1Q21 3) MUTATION ANALYSIS 209 (44%) 261 0.0605
(1.00) 		2.17e-05
(0.00801) 		0.000464
(0.157) 		0.414
(1.00) 		0.581
(1.00)
AMP PEAK 5(1Q22) MUTATION ANALYSIS 222 (47%) 248 0.00901
(1.00) 		6.12e-07
(0.000238) 		1.22e-06
(0.000469) 		0.359
(1.00) 		0.286
(1.00)
AMP PEAK 8(2Q13) MUTATION ANALYSIS 100 (21%) 370 0.00227
(0.68) 		0.000279
(0.0968) 		4.96e-18
(2.26e-15) 		0.535
(1.00) 		0.157
(1.00)
AMP PEAK 9(3P25 1) MUTATION ANALYSIS 66 (14%) 404 0.0474
(1.00) 		0.00018
(0.0631) 		1.77e-10
(7.4e-08) 		0.106
(1.00) 		0.6
(1.00)
AMP PEAK 10(3P14 1) MUTATION ANALYSIS 50 (11%) 420 0.000607
(0.201) 		0.0117
(1.00) 		0.000285
(0.0983) 		0.046
(1.00) 		0.383
(1.00)
AMP PEAK 11(3Q26 2) MUTATION ANALYSIS 143 (30%) 327 0.0058
(1.00) 		1.18e-10
(4.93e-08) 		7.81e-27
(3.78e-24) 		0.0772
(1.00) 		0.141
(1.00)
AMP PEAK 12(3Q26 2) MUTATION ANALYSIS 135 (29%) 335 0.00631
(1.00) 		2.05e-08
(8.27e-06) 		1.48e-26
(7.13e-24) 		0.0911
(1.00) 		0.0969
(1.00)
AMP PEAK 13(4P16 3) MUTATION ANALYSIS 43 (9%) 427 0.32
(1.00) 		1.79e-05
(0.00665) 		2.76e-12
(1.19e-09) 		0.597
(1.00) 		0.424
(1.00)
AMP PEAK 15(5Q35 3) MUTATION ANALYSIS 44 (9%) 426 0.315
(1.00) 		0.000282
(0.0975) 		2.19e-09
(9.07e-07) 		0.225
(1.00) 		0.305
(1.00)
AMP PEAK 16(6P24 2) MUTATION ANALYSIS 92 (20%) 378 0.233
(1.00) 		1.92e-06
(0.000732) 		1.17e-19
(5.41e-17) 		0.199
(1.00) 		0.617
(1.00)
AMP PEAK 19(8P11 21) MUTATION ANALYSIS 140 (30%) 330 0.000523
(0.175) 		0.3
(1.00) 		1.45e-07
(5.68e-05) 		0.0257
(1.00) 		0.00289
(0.846)
AMP PEAK 20(8Q24 21) MUTATION ANALYSIS 177 (38%) 293 0.00056
(0.187) 		0.457
(1.00) 		5.59e-14
(2.45e-11) 		0.0154
(1.00) 		0.0468
(1.00)
AMP PEAK 23(9Q34 3) MUTATION ANALYSIS 33 (7%) 437 0.0067
(1.00) 		0.000194
(0.0676) 		6.89e-07
(0.000268) 		0.843
(1.00) 		0.35
(1.00)
AMP PEAK 25(11P11 2) MUTATION ANALYSIS 42 (9%) 428 0.00405
(1.00) 		5.04e-05
(0.0182) 		6.02e-10
(2.51e-07) 		0.858
(1.00) 		0.41
(1.00)
AMP PEAK 31(13Q34) MUTATION ANALYSIS 48 (10%) 422 0.882
(1.00) 		1.47e-06
(0.000566) 		1.98e-13
(8.65e-11) 		0.867
(1.00) 		0.0706
(1.00)
AMP PEAK 34(16P11 2) MUTATION ANALYSIS 53 (11%) 417 0.00381
(1.00) 		5e-05
(0.0181) 		6.29e-14
(2.75e-11) 		0.75
(1.00) 		0.115
(1.00)
AMP PEAK 35(17Q11 2) MUTATION ANALYSIS 60 (13%) 410 0.00615
(1.00) 		0.000516
(0.173) 		4.96e-20
(2.3e-17) 		0.544
(1.00) 		0.00096
(0.306)
AMP PEAK 37(17Q25 1) MUTATION ANALYSIS 84 (18%) 386 0.00579
(1.00) 		7.77e-05
(0.0278) 		6.71e-17
(3.03e-14) 		0.598
(1.00) 		0.154
(1.00)
AMP PEAK 38(18P11 31) MUTATION ANALYSIS 75 (16%) 395 0.0723
(1.00) 		0.000173
(0.0607) 		1.47e-21
(6.94e-19) 		0.0372
(1.00) 		0.00499
(1.00)
AMP PEAK 40(19P13 2) MUTATION ANALYSIS 76 (16%) 394 0.145
(1.00) 		3.11e-11
(1.32e-08) 		3.37e-20
(1.57e-17) 		0.213
(1.00) 		0.528
(1.00)
AMP PEAK 41(19P13 11) MUTATION ANALYSIS 78 (17%) 392 0.0643
(1.00) 		1.01e-10
(4.27e-08) 		3.08e-23
(1.47e-20) 		0.0543
(1.00) 		0.183
(1.00)
AMP PEAK 43(20P13) MUTATION ANALYSIS 96 (20%) 374 0.188
(1.00) 		2.23e-05
(0.00824) 		1.19e-12
(5.15e-10) 		0.167
(1.00) 		0.136
(1.00)
AMP PEAK 45(20Q13 12) MUTATION ANALYSIS 125 (27%) 345 0.00773
(1.00) 		1.54e-08
(6.25e-06) 		2.09e-23
(1e-20) 		0.00568
(1.00) 		0.0238
(1.00)
AMP PEAK 46(20Q13 33) MUTATION ANALYSIS 121 (26%) 349 0.0243
(1.00) 		7.89e-08
(3.13e-05) 		1.09e-18
(5.03e-16) 		0.00341
(0.979) 		0.0152
(1.00)
AMP PEAK 47(22Q12 2) MUTATION ANALYSIS 52 (11%) 418 0.0071
(1.00) 		0.00148
(0.459) 		1.42e-20
(6.66e-18) 		0.143
(1.00) 		0.000681
(0.224)
DEL PEAK 1(1P36 11) MUTATION ANALYSIS 68 (14%) 402 0.022
(1.00) 		1.6e-05
(0.00599) 		1.58e-15
(7.04e-13) 		0.562
(1.00) 		0.0347
(1.00)
DEL PEAK 3(2Q22 1) MUTATION ANALYSIS 42 (9%) 428 1.16e-10
(4.88e-08) 		0.00526
(1.00) 		8.59e-09
(3.5e-06) 		0.00365
(1.00) 		0.00891
(1.00)
DEL PEAK 5(3P14 2) MUTATION ANALYSIS 65 (14%) 405 0.26
(1.00) 		0.000129
(0.046) 		3.02e-16
(1.35e-13) 		0.186
(1.00) 		0.593
(1.00)
DEL PEAK 7(4P16 3) MUTATION ANALYSIS 75 (16%) 395 0.00335
(0.967) 		8.5e-05
(0.0304) 		4.35e-17
(1.97e-14) 		0.265
(1.00) 		0.744
(1.00)
DEL PEAK 8(4P15 31) MUTATION ANALYSIS 77 (16%) 393 0.00411
(1.00) 		3.51e-05
(0.0129) 		6.46e-17
(2.92e-14) 		0.0542
(1.00) 		0.236
(1.00)
DEL PEAK 9(4Q22 1) MUTATION ANALYSIS 85 (18%) 385 0.00575
(1.00) 		4.86e-06
(0.00185) 		1.68e-26
(8.08e-24) 		0.185
(1.00) 		0.0306
(1.00)
DEL PEAK 10(4Q34 3) MUTATION ANALYSIS 105 (22%) 365 0.0149
(1.00) 		6e-06
(0.00226) 		1.95e-27
(9.47e-25) 		0.223
(1.00) 		0.0514
(1.00)
DEL PEAK 11(5Q11 2) MUTATION ANALYSIS 90 (19%) 380 0.0149
(1.00) 		6.22e-05
(0.0224) 		2.4e-25
(1.15e-22) 		0.365
(1.00) 		0.564
(1.00)
DEL PEAK 14(7Q11 22) MUTATION ANALYSIS 37 (8%) 433 0.88
(1.00) 		2.65e-05
(0.00973) 		2.72e-08
(1.09e-05) 		0.449
(1.00) 		0.679
(1.00)
DEL PEAK 15(7Q31 1) MUTATION ANALYSIS 46 (10%) 424 0.0815
(1.00) 		7.14e-07
(0.000276) 		2.99e-18
(1.36e-15) 		1
(1.00) 		0.235
(1.00)
DEL PEAK 16(7Q36 1) MUTATION ANALYSIS 56 (12%) 414 0.0182
(1.00) 		1.22e-09
(5.09e-07) 		3.46e-21
(1.63e-18) 		0.755
(1.00) 		0.131
(1.00)
DEL PEAK 17(8P23 2) MUTATION ANALYSIS 96 (20%) 374 0.00547
(1.00) 		0.000249
(0.0868) 		5.28e-30
(2.57e-27) 		0.259
(1.00) 		0.0147
(1.00)
DEL PEAK 18(8P21 2) MUTATION ANALYSIS 94 (20%) 376 0.0207
(1.00) 		7.73e-06
(0.0029) 		1.67e-37
(8.14e-35) 		0.372
(1.00) 		0.0565
(1.00)
DEL PEAK 21(9Q34 11) MUTATION ANALYSIS 109 (23%) 361 0.00548
(1.00) 		3.8e-08
(1.52e-05) 		1.39e-18
(6.36e-16) 		0.335
(1.00) 		0.286
(1.00)
DEL PEAK 23(11P15 5) MUTATION ANALYSIS 83 (18%) 387 0.0144
(1.00) 		1.52e-06
(0.000581) 		1.14e-18
(5.24e-16) 		0.0443
(1.00) 		0.0648
(1.00)
DEL PEAK 24(11Q14 1) MUTATION ANALYSIS 57 (12%) 413 0.0654
(1.00) 		1.76e-05
(0.00658) 		2.63e-15
(1.16e-12) 		0.35
(1.00) 		0.647
(1.00)
DEL PEAK 25(11Q25) MUTATION ANALYSIS 78 (17%) 392 0.00135
(0.424) 		0.000599
(0.199) 		1.31e-16
(5.89e-14) 		0.00924
(1.00) 		0.329
(1.00)
DEL PEAK 27(12Q24 33) MUTATION ANALYSIS 52 (11%) 418 0.121
(1.00) 		6.99e-05
(0.0251) 		3.41e-15
(1.51e-12) 		0.0726
(1.00) 		0.00968
(1.00)
DEL PEAK 29(13Q14 2) MUTATION ANALYSIS 83 (18%) 387 0.00224
(0.672) 		0.000395
(0.135) 		2.98e-07
(0.000116) 		0.0443
(1.00) 		0.333
(1.00)
DEL PEAK 31(15Q15 1) MUTATION ANALYSIS 115 (24%) 355 0.00116
(0.366) 		5.86e-08
(2.33e-05) 		3.86e-23
(1.83e-20) 		0.0332
(1.00) 		0.0333
(1.00)
DEL PEAK 32(15Q23) MUTATION ANALYSIS 96 (20%) 374 0.0376
(1.00) 		2e-05
(0.00743) 		4.74e-23
(2.25e-20) 		0.102
(1.00) 		0.307
(1.00)
DEL PEAK 33(16P13 3) MUTATION ANALYSIS 73 (16%) 397 0.0146
(1.00) 		1.81e-07
(7.11e-05) 		4.39e-20
(2.04e-17) 		0.325
(1.00) 		0.0616
(1.00)
DEL PEAK 34(16Q21) MUTATION ANALYSIS 129 (27%) 341 0.0382
(1.00) 		8.28e-09
(3.4e-06) 		3.09e-23
(1.47e-20) 		0.173
(1.00) 		0.101
(1.00)
DEL PEAK 35(16Q23 1) MUTATION ANALYSIS 139 (30%) 331 0.0047
(1.00) 		2.1e-07
(8.21e-05) 		1.28e-26
(6.18e-24) 		0.315
(1.00) 		0.00362
(1.00)
DEL PEAK 36(17P13 3) MUTATION ANALYSIS 100 (21%) 370 0.00201
(0.61) 		0.000146
(0.0519) 		1.62e-20
(7.58e-18) 		0.172
(1.00) 		0.248
(1.00)
DEL PEAK 37(17P11 2) MUTATION ANALYSIS 107 (23%) 363 0.00134
(0.422) 		8.51e-07
(0.000328) 		4.43e-27
(2.15e-24) 		0.182
(1.00) 		0.554
(1.00)
DEL PEAK 38(17P11 2) MUTATION ANALYSIS 100 (21%) 370 0.000894
(0.289) 		5.01e-06
(0.0019) 		1.04e-19
(4.81e-17) 		0.264
(1.00) 		0.712
(1.00)
DEL PEAK 39(17Q11 2) MUTATION ANALYSIS 86 (18%) 384 0.0438
(1.00) 		7.05e-06
(0.00265) 		2.11e-11
(9.01e-09) 		0.148
(1.00) 		0.173
(1.00)
DEL PEAK 40(17Q21 2) MUTATION ANALYSIS 91 (19%) 379 0.0036
(1.00) 		2.47e-05
(0.00909) 		6.67e-15
(2.93e-12) 		0.123
(1.00) 		0.124
(1.00)
DEL PEAK 47(22Q13 31) MUTATION ANALYSIS 112 (24%) 358 0.000949
(0.304) 		8.3e-09
(3.4e-06) 		4.94e-22
(2.33e-19) 		0.0945
(1.00) 		0.732
(1.00)
DEL PEAK 48(22Q13 32) MUTATION ANALYSIS 117 (25%) 353 0.000906
(0.291) 		1.05e-07
(4.14e-05) 		3.46e-22
(1.64e-19) 		0.0251
(1.00) 		0.354
(1.00)
DEL PEAK 49(XP21 1) MUTATION ANALYSIS 74 (16%) 396 0.000789
(0.257) 		0.000163
(0.0576) 		1.99e-15
(8.82e-13) 		0.162
(1.00) 		0.119
(1.00)
AMP PEAK 7(2P24 3) MUTATION ANALYSIS 104 (22%) 366 0.00339
(0.975) 		0.0182
(1.00) 		1.88e-11
(8.03e-09) 		0.0192
(1.00) 		0.726
(1.00)
AMP PEAK 14(5P15 33) MUTATION ANALYSIS 73 (16%) 397 0.00388
(1.00) 		0.0021
(0.633) 		1.92e-18
(8.75e-16) 		0.325
(1.00) 		0.0652
(1.00)
AMP PEAK 17(6Q25 1) MUTATION ANALYSIS 70 (15%) 400 0.278
(1.00) 		0.0263
(1.00) 		5.31e-06
(0.00201) 		0.668
(1.00) 		0.283
(1.00)
AMP PEAK 18(7Q22 1) MUTATION ANALYSIS 76 (16%) 394 0.000598
(0.199) 		0.0414
(1.00) 		0.00308
(0.899) 		0.128
(1.00) 		0.498
(1.00)
AMP PEAK 21(8Q24 21) MUTATION ANALYSIS 186 (40%) 284 0.0013
(0.41) 		0.176
(1.00) 		1.84e-15
(8.18e-13) 		0.00659
(1.00) 		0.00156
(0.481)
AMP PEAK 22(9P24 2) MUTATION ANALYSIS 53 (11%) 417 0.00203
(0.615) 		0.00435
(1.00) 		3.25e-09
(1.34e-06) 		0.199
(1.00) 		0.454
(1.00)
AMP PEAK 26(11Q13 2) MUTATION ANALYSIS 62 (13%) 408 0.00595
(1.00) 		0.00262
(0.772) 		2.31e-08
(9.29e-06) 		1
(1.00) 		0.114
(1.00)
AMP PEAK 27(11Q14 1) MUTATION ANALYSIS 46 (10%) 424 0.00104
(0.329) 		0.0103
(1.00) 		2.34e-09
(9.68e-07) 		0.307
(1.00) 		0.376
(1.00)
AMP PEAK 28(12P12 1) MUTATION ANALYSIS 73 (16%) 397 0.568
(1.00) 		0.194
(1.00) 		8.31e-09
(3.4e-06) 		0.673
(1.00) 		0.293
(1.00)
AMP PEAK 29(12Q13 11) MUTATION ANALYSIS 73 (16%) 397 0.802
(1.00) 		0.696
(1.00) 		4.93e-09
(2.03e-06) 		0.205
(1.00) 		0.248
(1.00)
AMP PEAK 30(12Q13 2) MUTATION ANALYSIS 81 (17%) 389 0.99
(1.00) 		0.0992
(1.00) 		5.02e-08
(2e-05) 		0.0585
(1.00) 		0.0692
(1.00)
AMP PEAK 33(15Q26 3) MUTATION ANALYSIS 31 (7%) 439 0.106
(1.00) 		0.0363
(1.00) 		0.000148
(0.0523) 		0.149
(1.00) 		0.0075
(1.00)
AMP PEAK 39(18Q11 2) MUTATION ANALYSIS 59 (13%) 411 0.0247
(1.00) 		0.00179
(0.547) 		1.93e-16
(8.63e-14) 		0.442
(1.00) 		0.0331
(1.00)
DEL PEAK 4(2Q37 3) MUTATION ANALYSIS 46 (10%) 424 0.116
(1.00) 		0.000477
(0.161) 		0.000804
(0.261) 		0.172
(1.00) 		0.0715
(1.00)
DEL PEAK 6(3Q13 31) MUTATION ANALYSIS 25 (5%) 445 0.988
(1.00) 		0.00775
(1.00) 		1.67e-06
(0.000639) 		0.373
(1.00) 		0.812
(1.00)
DEL PEAK 12(6Q26) MUTATION ANALYSIS 41 (9%) 429 0.361
(1.00) 		0.00247
(0.732) 		3.5e-11
(1.48e-08) 		0.858
(1.00) 		0.971
(1.00)
DEL PEAK 19(9P23) MUTATION ANALYSIS 58 (12%) 412 0.464
(1.00) 		0.0024
(0.714) 		1.21e-11
(5.19e-09) 		0.165
(1.00) 		0.158
(1.00)
DEL PEAK 22(10Q23 31) MUTATION ANALYSIS 62 (13%) 408 0.0355
(1.00) 		0.00313
(0.911) 		1.03e-08
(4.19e-06) 		0.023
(1.00) 		0.129
(1.00)
DEL PEAK 26(12Q23 1) MUTATION ANALYSIS 40 (9%) 430 0.00423
(1.00) 		0.00352
(0.999) 		1.51e-12
(6.52e-10) 		0.273
(1.00) 		0.0192
(1.00)
DEL PEAK 28(13Q11) MUTATION ANALYSIS 78 (17%) 392 0.00219
(0.659) 		0.0014
(0.437) 		9.14e-13
(3.96e-10) 		0.0995
(1.00) 		0.14
(1.00)
DEL PEAK 30(14Q13 1) MUTATION ANALYSIS 59 (13%) 411 0.00246
(0.732) 		0.00467
(1.00) 		8.22e-11
(3.47e-08) 		0.645
(1.00) 		0.927
(1.00)
DEL PEAK 41(18Q23) MUTATION ANALYSIS 81 (17%) 389 0.0038
(1.00) 		0.00267
(0.785) 		1.02e-16
(4.6e-14) 		0.00186
(0.566) 		0.0077
(1.00)
DEL PEAK 43(19P12) MUTATION ANALYSIS 43 (9%) 427 0.00734
(1.00) 		0.0494
(1.00) 		1.99e-08
(8.05e-06) 		0.157
(1.00) 		0.268
(1.00)
DEL PEAK 44(19Q13 43) MUTATION ANALYSIS 54 (11%) 416 0.00313
(0.911) 		0.0014
(0.436) 		3.29e-17
(1.5e-14) 		0.75
(1.00) 		0.051
(1.00)
DEL PEAK 46(22Q12 1) MUTATION ANALYSIS 77 (16%) 393 0.192
(1.00) 		0.00105
(0.333) 		1.29e-07
(5.09e-05) 		0.0542
(1.00) 		0.752
(1.00)
AMP PEAK 3(1P22 3) MUTATION ANALYSIS 79 (17%) 391 0.426
(1.00) 		0.00178
(0.547) 		0.00923
(1.00) 		0.892
(1.00) 		0.411
(1.00)
AMP PEAK 6(1Q42 3) MUTATION ANALYSIS 196 (42%) 274 0.235
(1.00) 		0.00166
(0.512) 		0.073
(1.00) 		0.536
(1.00) 		0.728
(1.00)
AMP PEAK 24(10Q22 2) MUTATION ANALYSIS 127 (27%) 343 0.283
(1.00) 		0.456
(1.00) 		0.033
(1.00) 		0.646
(1.00) 		0.502
(1.00)
AMP PEAK 48(XP11 23) MUTATION ANALYSIS 78 (17%) 392 0.225
(1.00) 		0.152
(1.00) 		0.00733
(1.00) 		0.0203
(1.00) 		0.437
(1.00)
AMP PEAK 49(XQ28) MUTATION ANALYSIS 78 (17%) 392 0.00415
(1.00) 		0.125
(1.00) 		0.000797
(0.259) 		1
(1.00) 		0.143
(1.00)
DEL PEAK 2(2P25 3) MUTATION ANALYSIS 23 (5%) 447 0.0172
(1.00) 		0.104
(1.00) 		0.00439
(1.00) 		0.101
(1.00) 		0.232
(1.00)
DEL PEAK 45(20P12 1) MUTATION ANALYSIS 29 (6%) 441 0.00344
(0.983) 		0.167
(1.00) 		0.000905
(0.291) 		0.675
(1.00) 		0.0861
(1.00)
'AMP PEAK 1(1P35.2) MUTATION STATUS' versus 'AGE'

P value = 0.000674 (t-test), Q value = 0.22

Table S1.  Gene #1: 'AMP PEAK 1(1P35.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 1(1P35.2) MUTATED 47 68.5 (9.4)
AMP PEAK 1(1P35.2) WILD-TYPE 422 63.2 (11.4)

Figure S1.  Get High-res Image Gene #1: 'AMP PEAK 1(1P35.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 1(1P35.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.46e-11 (Fisher's exact test), Q value = 6.2e-09

Table S2.  Gene #1: 'AMP PEAK 1(1P35.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 1(1P35.2) MUTATED 15 4 28
AMP PEAK 1(1P35.2) WILD-TYPE 344 14 65

Figure S2.  Get High-res Image Gene #1: 'AMP PEAK 1(1P35.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 2(1P34.2) MUTATION STATUS' versus 'AGE'

P value = 0.000435 (t-test), Q value = 0.15

Table S3.  Gene #2: 'AMP PEAK 2(1P34.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 2(1P34.2) MUTATED 59 68.4 (10.2)
AMP PEAK 2(1P34.2) WILD-TYPE 410 63.1 (11.3)

Figure S3.  Get High-res Image Gene #2: 'AMP PEAK 2(1P34.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 2(1P34.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.38e-16 (Fisher's exact test), Q value = 6.2e-14

Table S4.  Gene #2: 'AMP PEAK 2(1P34.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 2(1P34.2) MUTATED 17 6 36
AMP PEAK 2(1P34.2) WILD-TYPE 342 12 57

Figure S4.  Get High-res Image Gene #2: 'AMP PEAK 2(1P34.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus 'AGE'

P value = 2.17e-05 (t-test), Q value = 0.008

Table S5.  Gene #4: 'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 4(1Q21.3) MUTATED 209 66.2 (10.5)
AMP PEAK 4(1Q21.3) WILD-TYPE 260 61.8 (11.5)

Figure S5.  Get High-res Image Gene #4: 'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 0.000464 (Fisher's exact test), Q value = 0.16

Table S6.  Gene #4: 'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 4(1Q21.3) MUTATED 143 8 58
AMP PEAK 4(1Q21.3) WILD-TYPE 216 10 35

Figure S6.  Get High-res Image Gene #4: 'AMP PEAK 4(1Q21.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 5(1Q22) MUTATION STATUS' versus 'AGE'

P value = 6.12e-07 (t-test), Q value = 0.00024

Table S7.  Gene #5: 'AMP PEAK 5(1Q22) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 5(1Q22) MUTATED 222 66.5 (10.5)
AMP PEAK 5(1Q22) WILD-TYPE 247 61.3 (11.4)

Figure S7.  Get High-res Image Gene #5: 'AMP PEAK 5(1Q22) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 5(1Q22) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.22e-06 (Fisher's exact test), Q value = 0.00047

Table S8.  Gene #5: 'AMP PEAK 5(1Q22) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 5(1Q22) MUTATED 148 8 66
AMP PEAK 5(1Q22) WILD-TYPE 211 10 27

Figure S8.  Get High-res Image Gene #5: 'AMP PEAK 5(1Q22) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 7(2P24.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.88e-11 (Fisher's exact test), Q value = 8e-09

Table S9.  Gene #7: 'AMP PEAK 7(2P24.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 7(2P24.3) MUTATED 52 6 46
AMP PEAK 7(2P24.3) WILD-TYPE 307 12 47

Figure S9.  Get High-res Image Gene #7: 'AMP PEAK 7(2P24.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 8(2Q13) MUTATION STATUS' versus 'AGE'

P value = 0.000279 (t-test), Q value = 0.097

Table S10.  Gene #8: 'AMP PEAK 8(2Q13) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 8(2Q13) MUTATED 99 67.1 (9.4)
AMP PEAK 8(2Q13) WILD-TYPE 370 62.9 (11.6)

Figure S10.  Get High-res Image Gene #8: 'AMP PEAK 8(2Q13) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 8(2Q13) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.96e-18 (Fisher's exact test), Q value = 2.3e-15

Table S11.  Gene #8: 'AMP PEAK 8(2Q13) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 8(2Q13) MUTATED 43 4 53
AMP PEAK 8(2Q13) WILD-TYPE 316 14 40

Figure S11.  Get High-res Image Gene #8: 'AMP PEAK 8(2Q13) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 9(3P25.1) MUTATION STATUS' versus 'AGE'

P value = 0.00018 (t-test), Q value = 0.063

Table S12.  Gene #9: 'AMP PEAK 9(3P25.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 9(3P25.1) MUTATED 66 68.7 (10.9)
AMP PEAK 9(3P25.1) WILD-TYPE 403 63.0 (11.2)

Figure S12.  Get High-res Image Gene #9: 'AMP PEAK 9(3P25.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 9(3P25.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.77e-10 (Fisher's exact test), Q value = 7.4e-08

Table S13.  Gene #9: 'AMP PEAK 9(3P25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 9(3P25.1) MUTATED 30 1 35
AMP PEAK 9(3P25.1) WILD-TYPE 329 17 58

Figure S13.  Get High-res Image Gene #9: 'AMP PEAK 9(3P25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 10(3P14.1) MUTATION STATUS' versus 'Time to Death'

P value = 0.000607 (logrank test), Q value = 0.2

Table S14.  Gene #10: 'AMP PEAK 10(3P14.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 10(3P14.1) MUTATED 49 13 0.1 - 191.8 (17.9)
AMP PEAK 10(3P14.1) WILD-TYPE 418 43 0.0 - 185.8 (21.0)

Figure S14.  Get High-res Image Gene #10: 'AMP PEAK 10(3P14.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 10(3P14.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 0.000285 (Fisher's exact test), Q value = 0.098

Table S15.  Gene #10: 'AMP PEAK 10(3P14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 10(3P14.1) MUTATED 27 2 21
AMP PEAK 10(3P14.1) WILD-TYPE 332 16 72

Figure S15.  Get High-res Image Gene #10: 'AMP PEAK 10(3P14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus 'AGE'

P value = 1.18e-10 (t-test), Q value = 4.9e-08

Table S16.  Gene #11: 'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 11(3Q26.2) MUTATED 143 68.5 (9.5)
AMP PEAK 11(3Q26.2) WILD-TYPE 326 61.7 (11.4)

Figure S16.  Get High-res Image Gene #11: 'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 7.81e-27 (Fisher's exact test), Q value = 3.8e-24

Table S17.  Gene #11: 'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 11(3Q26.2) MUTATED 64 7 72
AMP PEAK 11(3Q26.2) WILD-TYPE 295 11 21

Figure S17.  Get High-res Image Gene #11: 'AMP PEAK 11(3Q26.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus 'AGE'

P value = 2.05e-08 (t-test), Q value = 8.3e-06

Table S18.  Gene #12: 'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 12(3Q26.2) MUTATED 135 68.0 (9.6)
AMP PEAK 12(3Q26.2) WILD-TYPE 334 62.0 (11.5)

Figure S18.  Get High-res Image Gene #12: 'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.48e-26 (Fisher's exact test), Q value = 7.1e-24

Table S19.  Gene #12: 'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 12(3Q26.2) MUTATED 59 6 70
AMP PEAK 12(3Q26.2) WILD-TYPE 300 12 23

Figure S19.  Get High-res Image Gene #12: 'AMP PEAK 12(3Q26.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 13(4P16.3) MUTATION STATUS' versus 'AGE'

P value = 1.79e-05 (t-test), Q value = 0.0067

Table S20.  Gene #13: 'AMP PEAK 13(4P16.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 13(4P16.3) MUTATED 43 70.2 (9.2)
AMP PEAK 13(4P16.3) WILD-TYPE 426 63.1 (11.3)

Figure S20.  Get High-res Image Gene #13: 'AMP PEAK 13(4P16.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 13(4P16.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.76e-12 (Fisher's exact test), Q value = 1.2e-09

Table S21.  Gene #13: 'AMP PEAK 13(4P16.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 13(4P16.3) MUTATED 13 1 29
AMP PEAK 13(4P16.3) WILD-TYPE 346 17 64

Figure S21.  Get High-res Image Gene #13: 'AMP PEAK 13(4P16.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 14(5P15.33) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.92e-18 (Fisher's exact test), Q value = 8.8e-16

Table S22.  Gene #14: 'AMP PEAK 14(5P15.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 14(5P15.33) MUTATED 25 3 45
AMP PEAK 14(5P15.33) WILD-TYPE 334 15 48

Figure S22.  Get High-res Image Gene #14: 'AMP PEAK 14(5P15.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus 'AGE'

P value = 0.000282 (t-test), Q value = 0.097

Table S23.  Gene #15: 'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 15(5Q35.3) MUTATED 44 69.8 (10.7)
AMP PEAK 15(5Q35.3) WILD-TYPE 425 63.1 (11.2)

Figure S23.  Get High-res Image Gene #15: 'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.19e-09 (Fisher's exact test), Q value = 9.1e-07

Table S24.  Gene #15: 'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 15(5Q35.3) MUTATED 16 2 26
AMP PEAK 15(5Q35.3) WILD-TYPE 343 16 67

Figure S24.  Get High-res Image Gene #15: 'AMP PEAK 15(5Q35.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 16(6P24.2) MUTATION STATUS' versus 'AGE'

P value = 1.92e-06 (t-test), Q value = 0.00073

Table S25.  Gene #16: 'AMP PEAK 16(6P24.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 16(6P24.2) MUTATED 92 68.6 (10.3)
AMP PEAK 16(6P24.2) WILD-TYPE 377 62.6 (11.2)

Figure S25.  Get High-res Image Gene #16: 'AMP PEAK 16(6P24.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 16(6P24.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.17e-19 (Fisher's exact test), Q value = 5.4e-17

Table S26.  Gene #16: 'AMP PEAK 16(6P24.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 16(6P24.2) MUTATED 36 4 52
AMP PEAK 16(6P24.2) WILD-TYPE 323 14 41

Figure S26.  Get High-res Image Gene #16: 'AMP PEAK 16(6P24.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 17(6Q25.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 5.31e-06 (Fisher's exact test), Q value = 0.002

Table S27.  Gene #17: 'AMP PEAK 17(6Q25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 17(6Q25.1) MUTATED 38 2 30
AMP PEAK 17(6Q25.1) WILD-TYPE 321 16 63

Figure S27.  Get High-res Image Gene #17: 'AMP PEAK 17(6Q25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 18(7Q22.1) MUTATION STATUS' versus 'Time to Death'

P value = 0.000598 (logrank test), Q value = 0.2

Table S28.  Gene #18: 'AMP PEAK 18(7Q22.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 18(7Q22.1) MUTATED 75 16 0.0 - 125.4 (15.4)
AMP PEAK 18(7Q22.1) WILD-TYPE 392 40 0.1 - 191.8 (23.3)

Figure S28.  Get High-res Image Gene #18: 'AMP PEAK 18(7Q22.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 19(8P11.21) MUTATION STATUS' versus 'Time to Death'

P value = 0.000523 (logrank test), Q value = 0.18

Table S29.  Gene #19: 'AMP PEAK 19(8P11.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 19(8P11.21) MUTATED 139 26 0.0 - 125.4 (17.9)
AMP PEAK 19(8P11.21) WILD-TYPE 328 30 0.1 - 191.8 (23.4)

Figure S29.  Get High-res Image Gene #19: 'AMP PEAK 19(8P11.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 19(8P11.21) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.45e-07 (Fisher's exact test), Q value = 5.7e-05

Table S30.  Gene #19: 'AMP PEAK 19(8P11.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 19(8P11.21) MUTATED 84 6 50
AMP PEAK 19(8P11.21) WILD-TYPE 275 12 43

Figure S30.  Get High-res Image Gene #19: 'AMP PEAK 19(8P11.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus 'Time to Death'

P value = 0.00056 (logrank test), Q value = 0.19

Table S31.  Gene #20: 'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 20(8Q24.21) MUTATED 176 31 0.0 - 191.8 (17.8)
AMP PEAK 20(8Q24.21) WILD-TYPE 291 25 0.1 - 185.8 (23.9)

Figure S31.  Get High-res Image Gene #20: 'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 5.59e-14 (Fisher's exact test), Q value = 2.4e-11

Table S32.  Gene #20: 'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 20(8Q24.21) MUTATED 102 8 67
AMP PEAK 20(8Q24.21) WILD-TYPE 257 10 26

Figure S32.  Get High-res Image Gene #20: 'AMP PEAK 20(8Q24.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 21(8Q24.21) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.84e-15 (Fisher's exact test), Q value = 8.2e-13

Table S33.  Gene #21: 'AMP PEAK 21(8Q24.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 21(8Q24.21) MUTATED 108 7 71
AMP PEAK 21(8Q24.21) WILD-TYPE 251 11 22

Figure S33.  Get High-res Image Gene #21: 'AMP PEAK 21(8Q24.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 22(9P24.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.25e-09 (Fisher's exact test), Q value = 1.3e-06

Table S34.  Gene #22: 'AMP PEAK 22(9P24.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 22(9P24.2) MUTATED 22 2 29
AMP PEAK 22(9P24.2) WILD-TYPE 337 16 64

Figure S34.  Get High-res Image Gene #22: 'AMP PEAK 22(9P24.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus 'AGE'

P value = 0.000194 (t-test), Q value = 0.068

Table S35.  Gene #23: 'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 23(9Q34.3) MUTATED 33 69.7 (8.4)
AMP PEAK 23(9Q34.3) WILD-TYPE 436 63.3 (11.4)

Figure S35.  Get High-res Image Gene #23: 'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.89e-07 (Fisher's exact test), Q value = 0.00027

Table S36.  Gene #23: 'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 23(9Q34.3) MUTATED 12 4 17
AMP PEAK 23(9Q34.3) WILD-TYPE 347 14 76

Figure S36.  Get High-res Image Gene #23: 'AMP PEAK 23(9Q34.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 25(11P11.2) MUTATION STATUS' versus 'AGE'

P value = 5.04e-05 (t-test), Q value = 0.018

Table S37.  Gene #25: 'AMP PEAK 25(11P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 25(11P11.2) MUTATED 42 70.0 (9.4)
AMP PEAK 25(11P11.2) WILD-TYPE 427 63.2 (11.3)

Figure S37.  Get High-res Image Gene #25: 'AMP PEAK 25(11P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 25(11P11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.02e-10 (Fisher's exact test), Q value = 2.5e-07

Table S38.  Gene #25: 'AMP PEAK 25(11P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 25(11P11.2) MUTATED 14 3 25
AMP PEAK 25(11P11.2) WILD-TYPE 345 15 68

Figure S38.  Get High-res Image Gene #25: 'AMP PEAK 25(11P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 26(11Q13.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.31e-08 (Fisher's exact test), Q value = 9.3e-06

Table S39.  Gene #26: 'AMP PEAK 26(11Q13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 26(11Q13.2) MUTATED 29 2 31
AMP PEAK 26(11Q13.2) WILD-TYPE 330 16 62

Figure S39.  Get High-res Image Gene #26: 'AMP PEAK 26(11Q13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 27(11Q14.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.34e-09 (Fisher's exact test), Q value = 9.7e-07

Table S40.  Gene #27: 'AMP PEAK 27(11Q14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 27(11Q14.1) MUTATED 19 0 27
AMP PEAK 27(11Q14.1) WILD-TYPE 340 18 66

Figure S40.  Get High-res Image Gene #27: 'AMP PEAK 27(11Q14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 28(12P12.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 8.31e-09 (Fisher's exact test), Q value = 3.4e-06

Table S41.  Gene #28: 'AMP PEAK 28(12P12.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 28(12P12.1) MUTATED 36 2 35
AMP PEAK 28(12P12.1) WILD-TYPE 323 16 58

Figure S41.  Get High-res Image Gene #28: 'AMP PEAK 28(12P12.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 29(12Q13.11) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.93e-09 (Fisher's exact test), Q value = 2e-06

Table S42.  Gene #29: 'AMP PEAK 29(12Q13.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 29(12Q13.11) MUTATED 35 3 35
AMP PEAK 29(12Q13.11) WILD-TYPE 324 15 58

Figure S42.  Get High-res Image Gene #29: 'AMP PEAK 29(12Q13.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 30(12Q13.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 5.02e-08 (Fisher's exact test), Q value = 2e-05

Table S43.  Gene #30: 'AMP PEAK 30(12Q13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 30(12Q13.2) MUTATED 42 3 36
AMP PEAK 30(12Q13.2) WILD-TYPE 317 15 57

Figure S43.  Get High-res Image Gene #30: 'AMP PEAK 30(12Q13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 31(13Q34) MUTATION STATUS' versus 'AGE'

P value = 1.47e-06 (t-test), Q value = 0.00057

Table S44.  Gene #31: 'AMP PEAK 31(13Q34) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 31(13Q34) MUTATED 48 69.7 (7.8)
AMP PEAK 31(13Q34) WILD-TYPE 421 63.1 (11.4)

Figure S44.  Get High-res Image Gene #31: 'AMP PEAK 31(13Q34) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 31(13Q34) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.98e-13 (Fisher's exact test), Q value = 8.6e-11

Table S45.  Gene #31: 'AMP PEAK 31(13Q34) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 31(13Q34) MUTATED 14 3 31
AMP PEAK 31(13Q34) WILD-TYPE 345 15 62

Figure S45.  Get High-res Image Gene #31: 'AMP PEAK 31(13Q34) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus 'Time to Death'

P value = 0.000704 (logrank test), Q value = 0.23

Table S46.  Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 32(14Q24.3) MUTATED 54 14 0.1 - 125.4 (18.1)
AMP PEAK 32(14Q24.3) WILD-TYPE 413 42 0.0 - 191.8 (20.9)

Figure S46.  Get High-res Image Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus 'AGE'

P value = 0.000179 (t-test), Q value = 0.063

Table S47.  Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 32(14Q24.3) MUTATED 54 68.6 (9.4)
AMP PEAK 32(14Q24.3) WILD-TYPE 415 63.1 (11.4)

Figure S47.  Get High-res Image Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 8.71e-13 (Fisher's exact test), Q value = 3.8e-10

Table S48.  Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 32(14Q24.3) MUTATED 18 4 32
AMP PEAK 32(14Q24.3) WILD-TYPE 341 14 61

Figure S48.  Get High-res Image Gene #32: 'AMP PEAK 32(14Q24.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 33(15Q26.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 0.000148 (Fisher's exact test), Q value = 0.052

Table S49.  Gene #33: 'AMP PEAK 33(15Q26.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 33(15Q26.3) MUTATED 15 0 16
AMP PEAK 33(15Q26.3) WILD-TYPE 344 18 77

Figure S49.  Get High-res Image Gene #33: 'AMP PEAK 33(15Q26.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 34(16P11.2) MUTATION STATUS' versus 'AGE'

P value = 5e-05 (t-test), Q value = 0.018

Table S50.  Gene #34: 'AMP PEAK 34(16P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 34(16P11.2) MUTATED 53 68.8 (8.6)
AMP PEAK 34(16P11.2) WILD-TYPE 416 63.1 (11.4)

Figure S50.  Get High-res Image Gene #34: 'AMP PEAK 34(16P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 34(16P11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.29e-14 (Fisher's exact test), Q value = 2.7e-11

Table S51.  Gene #34: 'AMP PEAK 34(16P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 34(16P11.2) MUTATED 17 2 34
AMP PEAK 34(16P11.2) WILD-TYPE 342 16 59

Figure S51.  Get High-res Image Gene #34: 'AMP PEAK 34(16P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus 'AGE'

P value = 0.000516 (t-test), Q value = 0.17

Table S52.  Gene #35: 'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 35(17Q11.2) MUTATED 60 67.8 (9.0)
AMP PEAK 35(17Q11.2) WILD-TYPE 409 63.2 (11.5)

Figure S52.  Get High-res Image Gene #35: 'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.96e-20 (Fisher's exact test), Q value = 2.3e-17

Table S53.  Gene #35: 'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 35(17Q11.2) MUTATED 15 5 40
AMP PEAK 35(17Q11.2) WILD-TYPE 344 13 53

Figure S53.  Get High-res Image Gene #35: 'AMP PEAK 35(17Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 36(17Q12) MUTATION STATUS' versus 'Time to Death'

P value = 0.000339 (logrank test), Q value = 0.12

Table S54.  Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 36(17Q12) MUTATED 61 14 0.1 - 97.4 (16.9)
AMP PEAK 36(17Q12) WILD-TYPE 406 42 0.0 - 191.8 (22.6)

Figure S54.  Get High-res Image Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 36(17Q12) MUTATION STATUS' versus 'AGE'

P value = 4.66e-05 (t-test), Q value = 0.017

Table S55.  Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 36(17Q12) MUTATED 62 68.8 (9.6)
AMP PEAK 36(17Q12) WILD-TYPE 407 63.0 (11.3)

Figure S55.  Get High-res Image Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 36(17Q12) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.19e-19 (Fisher's exact test), Q value = 5.5e-17

Table S56.  Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 36(17Q12) MUTATED 17 3 42
AMP PEAK 36(17Q12) WILD-TYPE 342 15 51

Figure S56.  Get High-res Image Gene #36: 'AMP PEAK 36(17Q12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus 'AGE'

P value = 7.77e-05 (t-test), Q value = 0.028

Table S57.  Gene #37: 'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 37(17Q25.1) MUTATED 84 67.8 (9.6)
AMP PEAK 37(17Q25.1) WILD-TYPE 385 62.9 (11.4)

Figure S57.  Get High-res Image Gene #37: 'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.71e-17 (Fisher's exact test), Q value = 3e-14

Table S58.  Gene #37: 'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 37(17Q25.1) MUTATED 32 8 44
AMP PEAK 37(17Q25.1) WILD-TYPE 327 10 49

Figure S58.  Get High-res Image Gene #37: 'AMP PEAK 37(17Q25.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 38(18P11.31) MUTATION STATUS' versus 'AGE'

P value = 0.000173 (t-test), Q value = 0.061

Table S59.  Gene #38: 'AMP PEAK 38(18P11.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 38(18P11.31) MUTATED 75 67.7 (9.3)
AMP PEAK 38(18P11.31) WILD-TYPE 394 63.0 (11.5)

Figure S59.  Get High-res Image Gene #38: 'AMP PEAK 38(18P11.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 38(18P11.31) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.47e-21 (Fisher's exact test), Q value = 6.9e-19

Table S60.  Gene #38: 'AMP PEAK 38(18P11.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 38(18P11.31) MUTATED 23 4 48
AMP PEAK 38(18P11.31) WILD-TYPE 336 14 45

Figure S60.  Get High-res Image Gene #38: 'AMP PEAK 38(18P11.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 39(18Q11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.93e-16 (Fisher's exact test), Q value = 8.6e-14

Table S61.  Gene #39: 'AMP PEAK 39(18Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 39(18Q11.2) MUTATED 18 3 38
AMP PEAK 39(18Q11.2) WILD-TYPE 341 15 55

Figure S61.  Get High-res Image Gene #39: 'AMP PEAK 39(18Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 40(19P13.2) MUTATION STATUS' versus 'AGE'

P value = 3.11e-11 (t-test), Q value = 1.3e-08

Table S62.  Gene #40: 'AMP PEAK 40(19P13.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 40(19P13.2) MUTATED 76 70.7 (8.7)
AMP PEAK 40(19P13.2) WILD-TYPE 393 62.4 (11.3)

Figure S62.  Get High-res Image Gene #40: 'AMP PEAK 40(19P13.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 40(19P13.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.37e-20 (Fisher's exact test), Q value = 1.6e-17

Table S63.  Gene #40: 'AMP PEAK 40(19P13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 40(19P13.2) MUTATED 24 7 45
AMP PEAK 40(19P13.2) WILD-TYPE 335 11 48

Figure S63.  Get High-res Image Gene #40: 'AMP PEAK 40(19P13.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 41(19P13.11) MUTATION STATUS' versus 'AGE'

P value = 1.01e-10 (t-test), Q value = 4.3e-08

Table S64.  Gene #41: 'AMP PEAK 41(19P13.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 41(19P13.11) MUTATED 78 70.7 (9.1)
AMP PEAK 41(19P13.11) WILD-TYPE 391 62.4 (11.2)

Figure S64.  Get High-res Image Gene #41: 'AMP PEAK 41(19P13.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 41(19P13.11) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.08e-23 (Fisher's exact test), Q value = 1.5e-20

Table S65.  Gene #41: 'AMP PEAK 41(19P13.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 41(19P13.11) MUTATED 23 6 49
AMP PEAK 41(19P13.11) WILD-TYPE 336 12 44

Figure S65.  Get High-res Image Gene #41: 'AMP PEAK 41(19P13.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 42(19Q12) MUTATION STATUS' versus 'Time to Death'

P value = 0.000294 (logrank test), Q value = 0.1

Table S66.  Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 42(19Q12) MUTATED 94 20 0.0 - 125.4 (17.3)
AMP PEAK 42(19Q12) WILD-TYPE 373 36 0.1 - 191.8 (23.0)

Figure S66.  Get High-res Image Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 42(19Q12) MUTATION STATUS' versus 'AGE'

P value = 2.62e-09 (t-test), Q value = 1.1e-06

Table S67.  Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 42(19Q12) MUTATED 94 69.2 (8.8)
AMP PEAK 42(19Q12) WILD-TYPE 375 62.4 (11.5)

Figure S67.  Get High-res Image Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 42(19Q12) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.16e-38 (Fisher's exact test), Q value = 1.1e-35

Table S68.  Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 42(19Q12) MUTATED 21 9 64
AMP PEAK 42(19Q12) WILD-TYPE 338 9 29

Figure S68.  Get High-res Image Gene #42: 'AMP PEAK 42(19Q12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 43(20P13) MUTATION STATUS' versus 'AGE'

P value = 2.23e-05 (t-test), Q value = 0.0082

Table S69.  Gene #43: 'AMP PEAK 43(20P13) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 43(20P13) MUTATED 96 68.3 (11.4)
AMP PEAK 43(20P13) WILD-TYPE 373 62.6 (11.0)

Figure S69.  Get High-res Image Gene #43: 'AMP PEAK 43(20P13) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 43(20P13) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.19e-12 (Fisher's exact test), Q value = 5.1e-10

Table S70.  Gene #43: 'AMP PEAK 43(20P13) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 43(20P13) MUTATED 46 4 46
AMP PEAK 43(20P13) WILD-TYPE 313 14 47

Figure S70.  Get High-res Image Gene #43: 'AMP PEAK 43(20P13) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus 'Time to Death'

P value = 0.000368 (logrank test), Q value = 0.13

Table S71.  Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
AMP PEAK 44(20Q11.21) MUTATED 117 23 0.0 - 149.5 (15.4)
AMP PEAK 44(20Q11.21) WILD-TYPE 350 33 0.1 - 191.8 (23.3)

Figure S71.  Get High-res Image Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus 'AGE'

P value = 6.22e-08 (t-test), Q value = 2.5e-05

Table S72.  Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 44(20Q11.21) MUTATED 118 68.3 (9.9)
AMP PEAK 44(20Q11.21) WILD-TYPE 351 62.2 (11.3)

Figure S72.  Get High-res Image Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 5.04e-25 (Fisher's exact test), Q value = 2.4e-22

Table S73.  Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 44(20Q11.21) MUTATED 48 6 64
AMP PEAK 44(20Q11.21) WILD-TYPE 311 12 29

Figure S73.  Get High-res Image Gene #44: 'AMP PEAK 44(20Q11.21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus 'AGE'

P value = 1.54e-08 (t-test), Q value = 6.3e-06

Table S74.  Gene #45: 'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 45(20Q13.12) MUTATED 125 68.5 (10.2)
AMP PEAK 45(20Q13.12) WILD-TYPE 344 62.1 (11.2)

Figure S74.  Get High-res Image Gene #45: 'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.09e-23 (Fisher's exact test), Q value = 1e-20

Table S75.  Gene #45: 'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 45(20Q13.12) MUTATED 54 7 64
AMP PEAK 45(20Q13.12) WILD-TYPE 305 11 29

Figure S75.  Get High-res Image Gene #45: 'AMP PEAK 45(20Q13.12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus 'AGE'

P value = 7.89e-08 (t-test), Q value = 3.1e-05

Table S76.  Gene #46: 'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
AMP PEAK 46(20Q13.33) MUTATED 121 68.4 (10.4)
AMP PEAK 46(20Q13.33) WILD-TYPE 348 62.2 (11.2)

Figure S76.  Get High-res Image Gene #46: 'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.09e-18 (Fisher's exact test), Q value = 5e-16

Table S77.  Gene #46: 'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 46(20Q13.33) MUTATED 56 6 59
AMP PEAK 46(20Q13.33) WILD-TYPE 303 12 34

Figure S77.  Get High-res Image Gene #46: 'AMP PEAK 46(20Q13.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.42e-20 (Fisher's exact test), Q value = 6.7e-18

Table S78.  Gene #47: 'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
AMP PEAK 47(22Q12.2) MUTATED 11 2 39
AMP PEAK 47(22Q12.2) WILD-TYPE 348 16 54

Figure S78.  Get High-res Image Gene #47: 'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus 'COMPLETENESS.OF.RESECTION'

P value = 0.000681 (Fisher's exact test), Q value = 0.22

Table S79.  Gene #47: 'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

nPatients R0 R1 R2 RX
ALL 324 24 16 26
AMP PEAK 47(22Q12.2) MUTATED 28 2 7 5
AMP PEAK 47(22Q12.2) WILD-TYPE 296 22 9 21

Figure S79.  Get High-res Image Gene #47: 'AMP PEAK 47(22Q12.2) MUTATION STATUS' versus Clinical Feature #5: 'COMPLETENESS.OF.RESECTION'

'DEL PEAK 1(1P36.11) MUTATION STATUS' versus 'AGE'

P value = 1.6e-05 (t-test), Q value = 0.006

Table S80.  Gene #50: 'DEL PEAK 1(1P36.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 1(1P36.11) MUTATED 68 68.9 (9.8)
DEL PEAK 1(1P36.11) WILD-TYPE 401 62.9 (11.3)

Figure S80.  Get High-res Image Gene #50: 'DEL PEAK 1(1P36.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 1(1P36.11) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.58e-15 (Fisher's exact test), Q value = 7e-13

Table S81.  Gene #50: 'DEL PEAK 1(1P36.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 1(1P36.11) MUTATED 24 4 40
DEL PEAK 1(1P36.11) WILD-TYPE 335 14 53

Figure S81.  Get High-res Image Gene #50: 'DEL PEAK 1(1P36.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus 'Time to Death'

P value = 1.16e-10 (logrank test), Q value = 4.9e-08

Table S82.  Gene #52: 'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
DEL PEAK 3(2Q22.1) MUTATED 42 15 0.1 - 125.4 (9.8)
DEL PEAK 3(2Q22.1) WILD-TYPE 425 41 0.0 - 191.8 (23.3)

Figure S82.  Get High-res Image Gene #52: 'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 8.59e-09 (Fisher's exact test), Q value = 3.5e-06

Table S83.  Gene #52: 'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 3(2Q22.1) MUTATED 16 1 25
DEL PEAK 3(2Q22.1) WILD-TYPE 343 17 68

Figure S83.  Get High-res Image Gene #52: 'DEL PEAK 3(2Q22.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 4(2Q37.3) MUTATION STATUS' versus 'AGE'

P value = 0.000477 (t-test), Q value = 0.16

Table S84.  Gene #53: 'DEL PEAK 4(2Q37.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 4(2Q37.3) MUTATED 46 68.3 (8.4)
DEL PEAK 4(2Q37.3) WILD-TYPE 423 63.3 (11.5)

Figure S84.  Get High-res Image Gene #53: 'DEL PEAK 4(2Q37.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 5(3P14.2) MUTATION STATUS' versus 'AGE'

P value = 0.000129 (t-test), Q value = 0.046

Table S85.  Gene #54: 'DEL PEAK 5(3P14.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 5(3P14.2) MUTATED 65 67.8 (8.4)
DEL PEAK 5(3P14.2) WILD-TYPE 404 63.1 (11.6)

Figure S85.  Get High-res Image Gene #54: 'DEL PEAK 5(3P14.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 5(3P14.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.02e-16 (Fisher's exact test), Q value = 1.3e-13

Table S86.  Gene #54: 'DEL PEAK 5(3P14.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 5(3P14.2) MUTATED 21 6 38
DEL PEAK 5(3P14.2) WILD-TYPE 338 12 55

Figure S86.  Get High-res Image Gene #54: 'DEL PEAK 5(3P14.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 6(3Q13.31) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.67e-06 (Fisher's exact test), Q value = 0.00064

Table S87.  Gene #55: 'DEL PEAK 6(3Q13.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 6(3Q13.31) MUTATED 8 1 16
DEL PEAK 6(3Q13.31) WILD-TYPE 351 17 77

Figure S87.  Get High-res Image Gene #55: 'DEL PEAK 6(3Q13.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 7(4P16.3) MUTATION STATUS' versus 'AGE'

P value = 8.5e-05 (t-test), Q value = 0.03

Table S88.  Gene #56: 'DEL PEAK 7(4P16.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 7(4P16.3) MUTATED 75 67.9 (9.3)
DEL PEAK 7(4P16.3) WILD-TYPE 394 63.0 (11.5)

Figure S88.  Get High-res Image Gene #56: 'DEL PEAK 7(4P16.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 7(4P16.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.35e-17 (Fisher's exact test), Q value = 2e-14

Table S89.  Gene #56: 'DEL PEAK 7(4P16.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 7(4P16.3) MUTATED 27 4 44
DEL PEAK 7(4P16.3) WILD-TYPE 332 14 49

Figure S89.  Get High-res Image Gene #56: 'DEL PEAK 7(4P16.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 8(4P15.31) MUTATION STATUS' versus 'AGE'

P value = 3.51e-05 (t-test), Q value = 0.013

Table S90.  Gene #57: 'DEL PEAK 8(4P15.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 8(4P15.31) MUTATED 77 68.1 (9.4)
DEL PEAK 8(4P15.31) WILD-TYPE 392 62.9 (11.4)

Figure S90.  Get High-res Image Gene #57: 'DEL PEAK 8(4P15.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 8(4P15.31) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.46e-17 (Fisher's exact test), Q value = 2.9e-14

Table S91.  Gene #57: 'DEL PEAK 8(4P15.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 8(4P15.31) MUTATED 29 3 45
DEL PEAK 8(4P15.31) WILD-TYPE 330 15 48

Figure S91.  Get High-res Image Gene #57: 'DEL PEAK 8(4P15.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus 'AGE'

P value = 4.86e-06 (t-test), Q value = 0.0018

Table S92.  Gene #58: 'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 9(4Q22.1) MUTATED 85 68.3 (9.2)
DEL PEAK 9(4Q22.1) WILD-TYPE 384 62.8 (11.5)

Figure S92.  Get High-res Image Gene #58: 'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.68e-26 (Fisher's exact test), Q value = 8.1e-24

Table S93.  Gene #58: 'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 9(4Q22.1) MUTATED 25 5 55
DEL PEAK 9(4Q22.1) WILD-TYPE 334 13 38

Figure S93.  Get High-res Image Gene #58: 'DEL PEAK 9(4Q22.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus 'AGE'

P value = 6e-06 (t-test), Q value = 0.0023

Table S94.  Gene #59: 'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 10(4Q34.3) MUTATED 105 68.0 (10.2)
DEL PEAK 10(4Q34.3) WILD-TYPE 364 62.6 (11.3)

Figure S94.  Get High-res Image Gene #59: 'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.95e-27 (Fisher's exact test), Q value = 9.5e-25

Table S95.  Gene #59: 'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 10(4Q34.3) MUTATED 37 6 62
DEL PEAK 10(4Q34.3) WILD-TYPE 322 12 31

Figure S95.  Get High-res Image Gene #59: 'DEL PEAK 10(4Q34.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus 'AGE'

P value = 6.22e-05 (t-test), Q value = 0.022

Table S96.  Gene #60: 'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 11(5Q11.2) MUTATED 90 67.8 (10.1)
DEL PEAK 11(5Q11.2) WILD-TYPE 379 62.8 (11.4)

Figure S96.  Get High-res Image Gene #60: 'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.4e-25 (Fisher's exact test), Q value = 1.2e-22

Table S97.  Gene #60: 'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 11(5Q11.2) MUTATED 31 2 57
DEL PEAK 11(5Q11.2) WILD-TYPE 328 16 36

Figure S97.  Get High-res Image Gene #60: 'DEL PEAK 11(5Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 12(6Q26) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.5e-11 (Fisher's exact test), Q value = 1.5e-08

Table S98.  Gene #61: 'DEL PEAK 12(6Q26) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 12(6Q26) MUTATED 12 3 26
DEL PEAK 12(6Q26) WILD-TYPE 347 15 67

Figure S98.  Get High-res Image Gene #61: 'DEL PEAK 12(6Q26) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 13(7P22.3) MUTATION STATUS' versus 'Time to Death'

P value = 0.000434 (logrank test), Q value = 0.15

Table S99.  Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
DEL PEAK 13(7P22.3) MUTATED 63 15 0.0 - 97.7 (18.2)
DEL PEAK 13(7P22.3) WILD-TYPE 404 41 0.1 - 191.8 (21.8)

Figure S99.  Get High-res Image Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'DEL PEAK 13(7P22.3) MUTATION STATUS' versus 'AGE'

P value = 6.1e-05 (t-test), Q value = 0.022

Table S100.  Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 13(7P22.3) MUTATED 63 68.8 (10.1)
DEL PEAK 13(7P22.3) WILD-TYPE 406 63.0 (11.3)

Figure S100.  Get High-res Image Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 13(7P22.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.18e-14 (Fisher's exact test), Q value = 5.2e-12

Table S101.  Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 13(7P22.3) MUTATED 22 5 37
DEL PEAK 13(7P22.3) WILD-TYPE 337 13 56

Figure S101.  Get High-res Image Gene #62: 'DEL PEAK 13(7P22.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus 'AGE'

P value = 2.65e-05 (t-test), Q value = 0.0097

Table S102.  Gene #63: 'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 14(7Q11.22) MUTATED 37 71.1 (9.8)
DEL PEAK 14(7Q11.22) WILD-TYPE 432 63.1 (11.2)

Figure S102.  Get High-res Image Gene #63: 'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.72e-08 (Fisher's exact test), Q value = 1.1e-05

Table S103.  Gene #63: 'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 14(7Q11.22) MUTATED 13 2 22
DEL PEAK 14(7Q11.22) WILD-TYPE 346 16 71

Figure S103.  Get High-res Image Gene #63: 'DEL PEAK 14(7Q11.22) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus 'AGE'

P value = 7.14e-07 (t-test), Q value = 0.00028

Table S104.  Gene #64: 'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 15(7Q31.1) MUTATED 46 70.2 (7.9)
DEL PEAK 15(7Q31.1) WILD-TYPE 423 63.1 (11.4)

Figure S104.  Get High-res Image Gene #64: 'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.99e-18 (Fisher's exact test), Q value = 1.4e-15

Table S105.  Gene #64: 'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 15(7Q31.1) MUTATED 9 3 34
DEL PEAK 15(7Q31.1) WILD-TYPE 350 15 59

Figure S105.  Get High-res Image Gene #64: 'DEL PEAK 15(7Q31.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus 'AGE'

P value = 1.22e-09 (t-test), Q value = 5.1e-07

Table S106.  Gene #65: 'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 16(7Q36.1) MUTATED 56 71.4 (8.5)
DEL PEAK 16(7Q36.1) WILD-TYPE 413 62.7 (11.2)

Figure S106.  Get High-res Image Gene #65: 'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.46e-21 (Fisher's exact test), Q value = 1.6e-18

Table S107.  Gene #65: 'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 16(7Q36.1) MUTATED 12 4 40
DEL PEAK 16(7Q36.1) WILD-TYPE 347 14 53

Figure S107.  Get High-res Image Gene #65: 'DEL PEAK 16(7Q36.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 17(8P23.2) MUTATION STATUS' versus 'AGE'

P value = 0.000249 (t-test), Q value = 0.087

Table S108.  Gene #66: 'DEL PEAK 17(8P23.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 17(8P23.2) MUTATED 95 67.1 (9.4)
DEL PEAK 17(8P23.2) WILD-TYPE 374 62.9 (11.6)

Figure S108.  Get High-res Image Gene #66: 'DEL PEAK 17(8P23.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 17(8P23.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 5.28e-30 (Fisher's exact test), Q value = 2.6e-27

Table S109.  Gene #66: 'DEL PEAK 17(8P23.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 17(8P23.2) MUTATED 30 4 62
DEL PEAK 17(8P23.2) WILD-TYPE 329 14 31

Figure S109.  Get High-res Image Gene #66: 'DEL PEAK 17(8P23.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 18(8P21.2) MUTATION STATUS' versus 'AGE'

P value = 7.73e-06 (t-test), Q value = 0.0029

Table S110.  Gene #67: 'DEL PEAK 18(8P21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 18(8P21.2) MUTATED 94 67.9 (9.2)
DEL PEAK 18(8P21.2) WILD-TYPE 375 62.7 (11.5)

Figure S110.  Get High-res Image Gene #67: 'DEL PEAK 18(8P21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 18(8P21.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.67e-37 (Fisher's exact test), Q value = 8.1e-35

Table S111.  Gene #67: 'DEL PEAK 18(8P21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 18(8P21.2) MUTATED 23 5 66
DEL PEAK 18(8P21.2) WILD-TYPE 336 13 27

Figure S111.  Get High-res Image Gene #67: 'DEL PEAK 18(8P21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 19(9P23) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.21e-11 (Fisher's exact test), Q value = 5.2e-09

Table S112.  Gene #68: 'DEL PEAK 19(9P23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 19(9P23) MUTATED 22 3 33
DEL PEAK 19(9P23) WILD-TYPE 337 15 60

Figure S112.  Get High-res Image Gene #68: 'DEL PEAK 19(9P23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus 'Time to Death'

P value = 0.000763 (logrank test), Q value = 0.25

Table S113.  Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
DEL PEAK 20(9Q21.2) MUTATED 103 21 0.1 - 125.4 (16.9)
DEL PEAK 20(9Q21.2) WILD-TYPE 364 35 0.0 - 191.8 (23.1)

Figure S113.  Get High-res Image Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus 'AGE'

P value = 3.62e-11 (t-test), Q value = 1.5e-08

Table S114.  Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 20(9Q21.2) MUTATED 104 69.6 (9.2)
DEL PEAK 20(9Q21.2) WILD-TYPE 365 62.1 (11.3)

Figure S114.  Get High-res Image Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.28e-20 (Fisher's exact test), Q value = 1.5e-17

Table S115.  Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 20(9Q21.2) MUTATED 42 8 54
DEL PEAK 20(9Q21.2) WILD-TYPE 317 10 39

Figure S115.  Get High-res Image Gene #69: 'DEL PEAK 20(9Q21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus 'AGE'

P value = 3.8e-08 (t-test), Q value = 1.5e-05

Table S116.  Gene #70: 'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 21(9Q34.11) MUTATED 109 68.4 (9.1)
DEL PEAK 21(9Q34.11) WILD-TYPE 360 62.4 (11.5)

Figure S116.  Get High-res Image Gene #70: 'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.39e-18 (Fisher's exact test), Q value = 6.4e-16

Table S117.  Gene #70: 'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 21(9Q34.11) MUTATED 47 8 54
DEL PEAK 21(9Q34.11) WILD-TYPE 312 10 39

Figure S117.  Get High-res Image Gene #70: 'DEL PEAK 21(9Q34.11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 22(10Q23.31) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.03e-08 (Fisher's exact test), Q value = 4.2e-06

Table S118.  Gene #71: 'DEL PEAK 22(10Q23.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 22(10Q23.31) MUTATED 28 3 31
DEL PEAK 22(10Q23.31) WILD-TYPE 331 15 62

Figure S118.  Get High-res Image Gene #71: 'DEL PEAK 22(10Q23.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 23(11P15.5) MUTATION STATUS' versus 'AGE'

P value = 1.52e-06 (t-test), Q value = 0.00058

Table S119.  Gene #72: 'DEL PEAK 23(11P15.5) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 23(11P15.5) MUTATED 83 68.6 (9.3)
DEL PEAK 23(11P15.5) WILD-TYPE 386 62.7 (11.4)

Figure S119.  Get High-res Image Gene #72: 'DEL PEAK 23(11P15.5) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 23(11P15.5) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.14e-18 (Fisher's exact test), Q value = 5.2e-16

Table S120.  Gene #72: 'DEL PEAK 23(11P15.5) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 23(11P15.5) MUTATED 30 6 47
DEL PEAK 23(11P15.5) WILD-TYPE 329 12 46

Figure S120.  Get High-res Image Gene #72: 'DEL PEAK 23(11P15.5) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus 'AGE'

P value = 1.76e-05 (t-test), Q value = 0.0066

Table S121.  Gene #73: 'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 24(11Q14.1) MUTATED 57 69.0 (8.9)
DEL PEAK 24(11Q14.1) WILD-TYPE 412 63.0 (11.4)

Figure S121.  Get High-res Image Gene #73: 'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.63e-15 (Fisher's exact test), Q value = 1.2e-12

Table S122.  Gene #73: 'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 24(11Q14.1) MUTATED 17 6 34
DEL PEAK 24(11Q14.1) WILD-TYPE 342 12 59

Figure S122.  Get High-res Image Gene #73: 'DEL PEAK 24(11Q14.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 25(11Q25) MUTATION STATUS' versus 'AGE'

P value = 0.000599 (t-test), Q value = 0.2

Table S123.  Gene #74: 'DEL PEAK 25(11Q25) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 25(11Q25) MUTATED 78 67.6 (10.4)
DEL PEAK 25(11Q25) WILD-TYPE 391 63.0 (11.3)

Figure S123.  Get High-res Image Gene #74: 'DEL PEAK 25(11Q25) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 25(11Q25) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.31e-16 (Fisher's exact test), Q value = 5.9e-14

Table S124.  Gene #74: 'DEL PEAK 25(11Q25) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 25(11Q25) MUTATED 29 5 44
DEL PEAK 25(11Q25) WILD-TYPE 330 13 49

Figure S124.  Get High-res Image Gene #74: 'DEL PEAK 25(11Q25) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 26(12Q23.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.51e-12 (Fisher's exact test), Q value = 6.5e-10

Table S125.  Gene #75: 'DEL PEAK 26(12Q23.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 26(12Q23.1) MUTATED 11 1 28
DEL PEAK 26(12Q23.1) WILD-TYPE 348 17 65

Figure S125.  Get High-res Image Gene #75: 'DEL PEAK 26(12Q23.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus 'AGE'

P value = 6.99e-05 (t-test), Q value = 0.025

Table S126.  Gene #76: 'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 27(12Q24.33) MUTATED 52 68.9 (9.0)
DEL PEAK 27(12Q24.33) WILD-TYPE 417 63.1 (11.4)

Figure S126.  Get High-res Image Gene #76: 'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.41e-15 (Fisher's exact test), Q value = 1.5e-12

Table S127.  Gene #76: 'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 27(12Q24.33) MUTATED 16 1 35
DEL PEAK 27(12Q24.33) WILD-TYPE 343 17 58

Figure S127.  Get High-res Image Gene #76: 'DEL PEAK 27(12Q24.33) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 28(13Q11) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 9.14e-13 (Fisher's exact test), Q value = 4e-10

Table S128.  Gene #77: 'DEL PEAK 28(13Q11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 28(13Q11) MUTATED 34 3 41
DEL PEAK 28(13Q11) WILD-TYPE 325 15 52

Figure S128.  Get High-res Image Gene #77: 'DEL PEAK 28(13Q11) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus 'AGE'

P value = 0.000395 (t-test), Q value = 0.13

Table S129.  Gene #78: 'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 29(13Q14.2) MUTATED 83 67.5 (10.0)
DEL PEAK 29(13Q14.2) WILD-TYPE 386 63.0 (11.4)

Figure S129.  Get High-res Image Gene #78: 'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.98e-07 (Fisher's exact test), Q value = 0.00012

Table S130.  Gene #78: 'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 29(13Q14.2) MUTATED 44 4 35
DEL PEAK 29(13Q14.2) WILD-TYPE 315 14 58

Figure S130.  Get High-res Image Gene #78: 'DEL PEAK 29(13Q14.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 30(14Q13.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 8.22e-11 (Fisher's exact test), Q value = 3.5e-08

Table S131.  Gene #79: 'DEL PEAK 30(14Q13.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 30(14Q13.1) MUTATED 23 5 31
DEL PEAK 30(14Q13.1) WILD-TYPE 336 13 62

Figure S131.  Get High-res Image Gene #79: 'DEL PEAK 30(14Q13.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus 'AGE'

P value = 5.86e-08 (t-test), Q value = 2.3e-05

Table S132.  Gene #80: 'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 31(15Q15.1) MUTATED 115 68.4 (9.9)
DEL PEAK 31(15Q15.1) WILD-TYPE 354 62.2 (11.3)

Figure S132.  Get High-res Image Gene #80: 'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.86e-23 (Fisher's exact test), Q value = 1.8e-20

Table S133.  Gene #80: 'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 31(15Q15.1) MUTATED 47 7 61
DEL PEAK 31(15Q15.1) WILD-TYPE 312 11 32

Figure S133.  Get High-res Image Gene #80: 'DEL PEAK 31(15Q15.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 32(15Q23) MUTATION STATUS' versus 'AGE'

P value = 2e-05 (t-test), Q value = 0.0074

Table S134.  Gene #81: 'DEL PEAK 32(15Q23) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 32(15Q23) MUTATED 96 67.8 (9.7)
DEL PEAK 32(15Q23) WILD-TYPE 373 62.7 (11.4)

Figure S134.  Get High-res Image Gene #81: 'DEL PEAK 32(15Q23) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 32(15Q23) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.74e-23 (Fisher's exact test), Q value = 2.2e-20

Table S135.  Gene #81: 'DEL PEAK 32(15Q23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 32(15Q23) MUTATED 35 5 56
DEL PEAK 32(15Q23) WILD-TYPE 324 13 37

Figure S135.  Get High-res Image Gene #81: 'DEL PEAK 32(15Q23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 33(16P13.3) MUTATION STATUS' versus 'AGE'

P value = 1.81e-07 (t-test), Q value = 7.1e-05

Table S136.  Gene #82: 'DEL PEAK 33(16P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 33(16P13.3) MUTATED 73 69.3 (8.8)
DEL PEAK 33(16P13.3) WILD-TYPE 396 62.7 (11.4)

Figure S136.  Get High-res Image Gene #82: 'DEL PEAK 33(16P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 33(16P13.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.39e-20 (Fisher's exact test), Q value = 2e-17

Table S137.  Gene #82: 'DEL PEAK 33(16P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 33(16P13.3) MUTATED 23 4 46
DEL PEAK 33(16P13.3) WILD-TYPE 336 14 47

Figure S137.  Get High-res Image Gene #82: 'DEL PEAK 33(16P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 34(16Q21) MUTATION STATUS' versus 'AGE'

P value = 8.28e-09 (t-test), Q value = 3.4e-06

Table S138.  Gene #83: 'DEL PEAK 34(16Q21) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 34(16Q21) MUTATED 129 68.2 (9.4)
DEL PEAK 34(16Q21) WILD-TYPE 340 62.1 (11.5)

Figure S138.  Get High-res Image Gene #83: 'DEL PEAK 34(16Q21) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 34(16Q21) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.09e-23 (Fisher's exact test), Q value = 1.5e-20

Table S139.  Gene #83: 'DEL PEAK 34(16Q21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 34(16Q21) MUTATED 57 7 65
DEL PEAK 34(16Q21) WILD-TYPE 302 11 28

Figure S139.  Get High-res Image Gene #83: 'DEL PEAK 34(16Q21) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus 'AGE'

P value = 2.1e-07 (t-test), Q value = 8.2e-05

Table S140.  Gene #84: 'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 35(16Q23.1) MUTATED 139 67.6 (9.6)
DEL PEAK 35(16Q23.1) WILD-TYPE 330 62.1 (11.6)

Figure S140.  Get High-res Image Gene #84: 'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.28e-26 (Fisher's exact test), Q value = 6.2e-24

Table S141.  Gene #84: 'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 35(16Q23.1) MUTATED 62 6 71
DEL PEAK 35(16Q23.1) WILD-TYPE 297 12 22

Figure S141.  Get High-res Image Gene #84: 'DEL PEAK 35(16Q23.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 36(17P13.3) MUTATION STATUS' versus 'AGE'

P value = 0.000146 (t-test), Q value = 0.052

Table S142.  Gene #85: 'DEL PEAK 36(17P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 36(17P13.3) MUTATED 100 67.2 (9.4)
DEL PEAK 36(17P13.3) WILD-TYPE 369 62.8 (11.6)

Figure S142.  Get High-res Image Gene #85: 'DEL PEAK 36(17P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 36(17P13.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.62e-20 (Fisher's exact test), Q value = 7.6e-18

Table S143.  Gene #85: 'DEL PEAK 36(17P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 36(17P13.3) MUTATED 39 8 53
DEL PEAK 36(17P13.3) WILD-TYPE 320 10 40

Figure S143.  Get High-res Image Gene #85: 'DEL PEAK 36(17P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 37(17P11.2) MUTATION STATUS' versus 'AGE'

P value = 8.51e-07 (t-test), Q value = 0.00033

Table S144.  Gene #86: 'DEL PEAK 37(17P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 37(17P11.2) MUTATED 107 68.1 (9.6)
DEL PEAK 37(17P11.2) WILD-TYPE 362 62.5 (11.4)

Figure S144.  Get High-res Image Gene #86: 'DEL PEAK 37(17P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 37(17P11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.43e-27 (Fisher's exact test), Q value = 2.1e-24

Table S145.  Gene #86: 'DEL PEAK 37(17P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 37(17P11.2) MUTATED 38 8 61
DEL PEAK 37(17P11.2) WILD-TYPE 321 10 32

Figure S145.  Get High-res Image Gene #86: 'DEL PEAK 37(17P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 38(17P11.2) MUTATION STATUS' versus 'AGE'

P value = 5.01e-06 (t-test), Q value = 0.0019

Table S146.  Gene #87: 'DEL PEAK 38(17P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 38(17P11.2) MUTATED 100 67.9 (9.5)
DEL PEAK 38(17P11.2) WILD-TYPE 369 62.6 (11.5)

Figure S146.  Get High-res Image Gene #87: 'DEL PEAK 38(17P11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 38(17P11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.04e-19 (Fisher's exact test), Q value = 4.8e-17

Table S147.  Gene #87: 'DEL PEAK 38(17P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 38(17P11.2) MUTATED 40 7 53
DEL PEAK 38(17P11.2) WILD-TYPE 319 11 40

Figure S147.  Get High-res Image Gene #87: 'DEL PEAK 38(17P11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus 'AGE'

P value = 7.05e-06 (t-test), Q value = 0.0027

Table S148.  Gene #88: 'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 39(17Q11.2) MUTATED 86 68.3 (9.7)
DEL PEAK 39(17Q11.2) WILD-TYPE 383 62.7 (11.4)

Figure S148.  Get High-res Image Gene #88: 'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 2.11e-11 (Fisher's exact test), Q value = 9e-09

Table S149.  Gene #88: 'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 39(17Q11.2) MUTATED 40 5 41
DEL PEAK 39(17Q11.2) WILD-TYPE 319 13 52

Figure S149.  Get High-res Image Gene #88: 'DEL PEAK 39(17Q11.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus 'AGE'

P value = 2.47e-05 (t-test), Q value = 0.0091

Table S150.  Gene #89: 'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 40(17Q21.2) MUTATED 91 67.9 (9.9)
DEL PEAK 40(17Q21.2) WILD-TYPE 378 62.8 (11.4)

Figure S150.  Get High-res Image Gene #89: 'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 6.67e-15 (Fisher's exact test), Q value = 2.9e-12

Table S151.  Gene #89: 'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 40(17Q21.2) MUTATED 39 6 46
DEL PEAK 40(17Q21.2) WILD-TYPE 320 12 47

Figure S151.  Get High-res Image Gene #89: 'DEL PEAK 40(17Q21.2) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 41(18Q23) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.02e-16 (Fisher's exact test), Q value = 4.6e-14

Table S152.  Gene #90: 'DEL PEAK 41(18Q23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 41(18Q23) MUTATED 31 5 45
DEL PEAK 41(18Q23) WILD-TYPE 328 13 48

Figure S152.  Get High-res Image Gene #90: 'DEL PEAK 41(18Q23) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 42(19P13.3) MUTATION STATUS' versus 'Time to Death'

P value = 3.7e-05 (logrank test), Q value = 0.014

Table S153.  Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 467 56 0.0 - 191.8 (20.9)
DEL PEAK 42(19P13.3) MUTATED 130 27 0.0 - 125.4 (17.3)
DEL PEAK 42(19P13.3) WILD-TYPE 337 29 0.1 - 191.8 (23.3)

Figure S153.  Get High-res Image Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #1: 'Time to Death'

'DEL PEAK 42(19P13.3) MUTATION STATUS' versus 'AGE'

P value = 7.8e-12 (t-test), Q value = 3.4e-09

Table S154.  Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 42(19P13.3) MUTATED 131 68.9 (8.8)
DEL PEAK 42(19P13.3) WILD-TYPE 338 61.8 (11.5)

Figure S154.  Get High-res Image Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 42(19P13.3) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.91e-54 (Fisher's exact test), Q value = 9.4e-52

Table S155.  Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 42(19P13.3) MUTATED 37 8 86
DEL PEAK 42(19P13.3) WILD-TYPE 322 10 7

Figure S155.  Get High-res Image Gene #91: 'DEL PEAK 42(19P13.3) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 43(19P12) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.99e-08 (Fisher's exact test), Q value = 8e-06

Table S156.  Gene #92: 'DEL PEAK 43(19P12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 43(19P12) MUTATED 16 4 23
DEL PEAK 43(19P12) WILD-TYPE 343 14 70

Figure S156.  Get High-res Image Gene #92: 'DEL PEAK 43(19P12) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 44(19Q13.43) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.29e-17 (Fisher's exact test), Q value = 1.5e-14

Table S157.  Gene #93: 'DEL PEAK 44(19Q13.43) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 44(19Q13.43) MUTATED 14 4 36
DEL PEAK 44(19Q13.43) WILD-TYPE 345 14 57

Figure S157.  Get High-res Image Gene #93: 'DEL PEAK 44(19Q13.43) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 46(22Q12.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.29e-07 (Fisher's exact test), Q value = 5.1e-05

Table S158.  Gene #95: 'DEL PEAK 46(22Q12.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 46(22Q12.1) MUTATED 39 7 31
DEL PEAK 46(22Q12.1) WILD-TYPE 320 11 62

Figure S158.  Get High-res Image Gene #95: 'DEL PEAK 46(22Q12.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus 'AGE'

P value = 8.3e-09 (t-test), Q value = 3.4e-06

Table S159.  Gene #96: 'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 47(22Q13.31) MUTATED 112 68.7 (9.5)
DEL PEAK 47(22Q13.31) WILD-TYPE 357 62.2 (11.4)

Figure S159.  Get High-res Image Gene #96: 'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 4.94e-22 (Fisher's exact test), Q value = 2.3e-19

Table S160.  Gene #96: 'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 47(22Q13.31) MUTATED 46 7 59
DEL PEAK 47(22Q13.31) WILD-TYPE 313 11 34

Figure S160.  Get High-res Image Gene #96: 'DEL PEAK 47(22Q13.31) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus 'AGE'

P value = 1.05e-07 (t-test), Q value = 4.1e-05

Table S161.  Gene #97: 'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 48(22Q13.32) MUTATED 117 68.4 (10.1)
DEL PEAK 48(22Q13.32) WILD-TYPE 352 62.2 (11.3)

Figure S161.  Get High-res Image Gene #97: 'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 3.46e-22 (Fisher's exact test), Q value = 1.6e-19

Table S162.  Gene #97: 'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 48(22Q13.32) MUTATED 49 8 60
DEL PEAK 48(22Q13.32) WILD-TYPE 310 10 33

Figure S162.  Get High-res Image Gene #97: 'DEL PEAK 48(22Q13.32) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

'DEL PEAK 49(XP21.1) MUTATION STATUS' versus 'AGE'

P value = 0.000163 (t-test), Q value = 0.058

Table S163.  Gene #98: 'DEL PEAK 49(XP21.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

nPatients Mean (Std.Dev)
ALL 469 63.8 (11.3)
DEL PEAK 49(XP21.1) MUTATED 74 67.8 (9.4)
DEL PEAK 49(XP21.1) WILD-TYPE 395 63.0 (11.5)

Figure S163.  Get High-res Image Gene #98: 'DEL PEAK 49(XP21.1) MUTATION STATUS' versus Clinical Feature #2: 'AGE'

'DEL PEAK 49(XP21.1) MUTATION STATUS' versus 'HISTOLOGICAL.TYPE'

P value = 1.99e-15 (Fisher's exact test), Q value = 8.8e-13

Table S164.  Gene #98: 'DEL PEAK 49(XP21.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

nPatients ENDOMETRIOID ENDOMETRIAL ADENOCARCINOMA MIXED SEROUS AND ENDOMETRIOID SEROUS ENDOMETRIAL ADENOCARCINOMA
ALL 359 18 93
DEL PEAK 49(XP21.1) MUTATED 29 2 43
DEL PEAK 49(XP21.1) WILD-TYPE 330 16 50

Figure S164.  Get High-res Image Gene #98: 'DEL PEAK 49(XP21.1) MUTATION STATUS' versus Clinical Feature #3: 'HISTOLOGICAL.TYPE'

Methods & Data
Input

  • Copy number data file = transformed.cor.cli.txt

  • Clinical data file = UCEC-TP.clin.merged.picked.txt

  • Number of patients = 470

  • Number of significantly focal cnvs = 98

  • Number of selected clinical features = 5

  • Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Student's t-test analysis

For continuous numerical clinical features, two-tailed Student's t test with unequal variance (Lehmann and Romano 2005) was applied to compare the clinical values between tumors with and without gene mutations using 't.test' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Lehmann and Romano, Testing Statistical Hypotheses (3E ed.), New York: Springer. ISBN 0387988645 (2005)
[3] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[4] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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