Correlation between gene mutation status and molecular subtypes

Adrenocortical Carcinoma (Primary solid tumor)

16 April 2014 | analyses__2014_04_16

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1H130KT

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 151 genes and 8 molecular subtypes across 91 patients, 2 significant findings detected with P value < 0.05 and Q value < 0.25.

CTNNB1 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 151 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 2 significant findings detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Chi-square test	Chi-square test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
CTNNB1	14 (15%)	77	0.435 (1.00)	0.0574 (1.00)	0.000193 (0.223)	3.12e-05 (0.0359)	0.000643 (0.739)	0.361 (1.00)	0.00645 (1.00)	0.251 (1.00)
CLIC6	11 (12%)	80	0.933 (1.00)	0.862 (1.00)	0.285 (1.00)	1 (1.00)	0.311 (1.00)	0.314 (1.00)	0.342 (1.00)	0.458 (1.00)
NMU	10 (11%)	81	0.151 (1.00)	0.442 (1.00)	0.137 (1.00)	0.112 (1.00)	0.15 (1.00)	0.407 (1.00)	0.299 (1.00)	0.788 (1.00)
LPPR2	6 (7%)	85	0.671 (1.00)	0.559 (1.00)	0.246 (1.00)	0.198 (1.00)	0.475 (1.00)	0.711 (1.00)	0.467 (1.00)	0.336 (1.00)
CHDH	6 (7%)	85	0.138 (1.00)	0.193 (1.00)	0.888 (1.00)	0.488 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
C4ORF32	9 (10%)	82	0.874 (1.00)	0.494 (1.00)	0.165 (1.00)	0.568 (1.00)	0.563 (1.00)	1 (1.00)	0.118 (1.00)	0.724 (1.00)
SYT8	14 (15%)	77	0.897 (1.00)	0.555 (1.00)	0.677 (1.00)	0.656 (1.00)	1 (1.00)	0.728 (1.00)	0.837 (1.00)	0.291 (1.00)
RINL	19 (21%)	72	0.0471 (1.00)	0.567 (1.00)	0.13 (1.00)	0.128 (1.00)	0.409 (1.00)	0.737 (1.00)	0.234 (1.00)	1 (1.00)
OBSCN	29 (32%)	62	0.527 (1.00)	0.494 (1.00)	0.223 (1.00)	0.802 (1.00)	0.256 (1.00)	0.762 (1.00)	0.208 (1.00)	0.599 (1.00)
MAP1S	9 (10%)	82	0.305 (1.00)	0.254 (1.00)	0.174 (1.00)	1 (1.00)	0.9 (1.00)	0.878 (1.00)	0.808 (1.00)	0.788 (1.00)
GPRIN2	11 (12%)	80	0.576 (1.00)	0.746 (1.00)	0.734 (1.00)	0.181 (1.00)	0.468 (1.00)	0.275 (1.00)	0.331 (1.00)	0.376 (1.00)
ATP9B	5 (5%)	86	0.853 (1.00)	0.292 (1.00)	0.804 (1.00)	0.861 (1.00)	1 (1.00)	1 (1.00)	0.703 (1.00)	1 (1.00)
RREB1	11 (12%)	80	0.0932 (1.00)	0.606 (1.00)	0.547 (1.00)	0.352 (1.00)	1 (1.00)	0.444 (1.00)	0.89 (1.00)	0.601 (1.00)
IDUA	15 (16%)	76	0.25 (1.00)	0.517 (1.00)	0.489 (1.00)	0.672 (1.00)	0.15 (1.00)	1 (1.00)	0.253 (1.00)	1 (1.00)
RGS9BP	11 (12%)	80	0.351 (1.00)	0.715 (1.00)	1 (1.00)	0.821 (1.00)	0.451 (1.00)	0.79 (1.00)	0.685 (1.00)	0.799 (1.00)
WDR34	11 (12%)	80	0.753 (1.00)	0.823 (1.00)	0.965 (1.00)	0.634 (1.00)	0.617 (1.00)	0.239 (1.00)	0.906 (1.00)	0.178 (1.00)
NOTCH2	12 (13%)	79	0.333 (1.00)	0.573 (1.00)	1 (1.00)	0.644 (1.00)	0.11 (1.00)	0.877 (1.00)	0.181 (1.00)	0.458 (1.00)
TMEM189	12 (13%)	79	0.188 (1.00)	0.854 (1.00)	0.319 (1.00)	0.0878 (1.00)	0.306 (1.00)	0.692 (1.00)	0.376 (1.00)	0.554 (1.00)
TAF5	12 (13%)	79	0.408 (1.00)	0.666 (1.00)	1 (1.00)	0.499 (1.00)	0.393 (1.00)	0.0703 (1.00)	0.187 (1.00)	0.11 (1.00)
LRP11	9 (10%)	82	0.00701 (1.00)	0.373 (1.00)	1 (1.00)	0.549 (1.00)	0.594 (1.00)	0.64 (1.00)	0.679 (1.00)	1 (1.00)
FPGS	14 (15%)	77	0.262 (1.00)	0.515 (1.00)	0.0636 (1.00)	1 (1.00)	0.64 (1.00)	1 (1.00)	0.363 (1.00)	1 (1.00)
BAG1	6 (7%)	85	0.956 (1.00)	0.359 (1.00)	0.626 (1.00)	0.728 (1.00)	0.346 (1.00)	0.0804 (1.00)	0.186 (1.00)	0.163 (1.00)
FZD1	6 (7%)	85	0.424 (1.00)	0.333 (1.00)	0.612 (1.00)	0.113 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
TOR3A	25 (27%)	66	0.674 (1.00)	0.0628 (1.00)	0.447 (1.00)	0.0295 (1.00)	0.887 (1.00)	0.221 (1.00)	0.925 (1.00)	0.447 (1.00)
TMEM200C	6 (7%)	85	0.652 (1.00)	0.333 (1.00)	0.0137 (1.00)	0.358 (1.00)	1 (1.00)	1 (1.00)	0.597 (1.00)	1 (1.00)
ZNF517	33 (36%)	58	0.59 (1.00)	0.962 (1.00)	0.688 (1.00)	0.857 (1.00)	0.519 (1.00)	1 (1.00)	0.66 (1.00)	1 (1.00)
DMRT1	5 (5%)	86	0.635 (1.00)	0.24 (1.00)	0.21 (1.00)	0.0922 (1.00)	0.0209 (1.00)	0.00222 (1.00)	0.0623 (1.00)	0.00318 (1.00)
GLTPD2	19 (21%)	72	0.339 (1.00)	0.962 (1.00)	0.955 (1.00)	0.683 (1.00)	0.477 (1.00)	0.515 (1.00)	0.721 (1.00)	0.849 (1.00)
SEMA5B	16 (18%)	75	0.191 (1.00)	0.637 (1.00)	0.114 (1.00)	0.314 (1.00)	0.78 (1.00)	0.826 (1.00)	1 (1.00)	0.83 (1.00)
TNIP2	7 (8%)	84	0.589 (1.00)	0.293 (1.00)	0.708 (1.00)	0.597 (1.00)	0.846 (1.00)	0.303 (1.00)	1 (1.00)	0.213 (1.00)
HHIPL1	14 (15%)	77	0.134 (1.00)	0.961 (1.00)	0.314 (1.00)	0.845 (1.00)	0.0149 (1.00)	0.0376 (1.00)	0.0212 (1.00)	0.124 (1.00)
HECTD2	7 (8%)	84	0.746 (1.00)	0.388 (1.00)	0.392 (1.00)	0.415 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	1 (1.00)
ADAD2	15 (16%)	76	0.138 (1.00)	0.141 (1.00)	0.889 (1.00)	0.25 (1.00)	0.578 (1.00)	0.567 (1.00)	0.628 (1.00)	0.638 (1.00)
ZFPM1	48 (53%)	43	0.225 (1.00)	0.903 (1.00)	0.916 (1.00)	0.838 (1.00)	0.829 (1.00)	0.225 (1.00)	0.548 (1.00)	0.413 (1.00)
CLDN23	13 (14%)	78	0.207 (1.00)	0.361 (1.00)	0.0204 (1.00)	0.15 (1.00)	0.137 (1.00)	0.303 (1.00)	0.147 (1.00)	0.509 (1.00)
CCDC105	11 (12%)	80	0.0641 (1.00)	0.00159 (1.00)	0.882 (1.00)	0.121 (1.00)	0.363 (1.00)	0.0204 (1.00)	0.279 (1.00)	0.0166 (1.00)
DMKN	3 (3%)	88	0.688 (1.00)	0.333 (1.00)	0.612 (1.00)	0.113 (1.00)	0.00708 (1.00)	1 (1.00)	0.0103 (1.00)	1 (1.00)
NOL9	12 (13%)	79	0.469 (1.00)	0.647 (1.00)	0.295 (1.00)	0.225 (1.00)	0.812 (1.00)	0.692 (1.00)	0.903 (1.00)	0.554 (1.00)
C19ORF10	10 (11%)	81	0.638 (1.00)	0.16 (1.00)	0.124 (1.00)	0.00708 (1.00)	0.237 (1.00)	0.757 (1.00)	0.105 (1.00)	0.764 (1.00)
ZNF598	19 (21%)	72	0.427 (1.00)	0.414 (1.00)	0.777 (1.00)	0.93 (1.00)	0.787 (1.00)	0.836 (1.00)	0.68 (1.00)	0.638 (1.00)
THEM4	14 (15%)	77	0.00763 (1.00)	0.251 (1.00)	0.97 (1.00)	0.917 (1.00)	0.484 (1.00)	0.141 (1.00)	0.762 (1.00)	0.0872 (1.00)
LRIG1	32 (35%)	59	0.533 (1.00)	0.731 (1.00)	0.656 (1.00)	0.707 (1.00)	0.296 (1.00)	0.818 (1.00)	0.902 (1.00)	0.631 (1.00)
MUC5B	25 (27%)	66	0.759 (1.00)	0.248 (1.00)	0.337 (1.00)	0.291 (1.00)	0.655 (1.00)	0.927 (1.00)	0.485 (1.00)	0.873 (1.00)
CTGF	6 (7%)	85	0.632 (1.00)	0.397 (1.00)	0.754 (1.00)	0.728 (1.00)	0.277 (1.00)	0.199 (1.00)	0.423 (1.00)	0.163 (1.00)
AMDHD1	18 (20%)	73	0.0677 (1.00)	0.896 (1.00)	0.563 (1.00)	0.652 (1.00)	0.273 (1.00)	0.294 (1.00)	0.0186 (1.00)	0.394 (1.00)
RNF149	7 (8%)	84	0.768 (1.00)	0.56 (1.00)	0.888 (1.00)	0.762 (1.00)	0.0871 (1.00)	0.123 (1.00)	0.146 (1.00)	0.141 (1.00)
MSH3	5 (5%)	86	0.00899 (1.00)	0.592 (1.00)	0.0701 (1.00)	0.684 (1.00)	0.132 (1.00)	0.342 (1.00)	0.182 (1.00)	0.192 (1.00)
ALPPL2	8 (9%)	83	0.907 (1.00)	0.121 (1.00)	0.339 (1.00)	0.365 (1.00)	0.703 (1.00)	0.258 (1.00)	0.8 (1.00)	0.281 (1.00)
SNED1	7 (8%)	84	0.671 (1.00)	0.623 (1.00)	0.547 (1.00)	0.711 (1.00)	0.0417 (1.00)	0.862 (1.00)	0.0706 (1.00)	0.865 (1.00)
NOXA1	5 (5%)	86	0.284 (1.00)	0.371 (1.00)	0.347 (1.00)	0.258 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
OPRD1	26 (29%)	65	0.24 (1.00)	0.832 (1.00)	0.646 (1.00)	0.759 (1.00)	0.465 (1.00)	0.466 (1.00)	0.695 (1.00)	0.629 (1.00)
CCDC102A	26 (29%)	65	0.587 (1.00)	0.864 (1.00)	0.908 (1.00)	0.82 (1.00)	0.544 (1.00)	0.586 (1.00)	0.677 (1.00)	0.385 (1.00)
KCTD3	8 (9%)	83	0.11 (1.00)	0.0699 (1.00)	0.686 (1.00)	0.488 (1.00)	1 (1.00)	0.711 (1.00)	1 (1.00)	0.612 (1.00)
C1ORF106	16 (18%)	75	0.9 (1.00)	0.439 (1.00)	0.518 (1.00)	0.816 (1.00)	1 (1.00)	0.537 (1.00)	0.749 (1.00)	0.634 (1.00)
KCNK17	19 (21%)	72	0.135 (1.00)	0.0959 (1.00)	0.201 (1.00)	0.0117 (1.00)	1 (1.00)	0.278 (1.00)	0.881 (1.00)	0.497 (1.00)
LACTB	27 (30%)	64	0.0645 (1.00)	0.343 (1.00)	0.906 (1.00)	1 (1.00)	0.571 (1.00)	0.708 (1.00)	0.485 (1.00)	0.858 (1.00)
TRIOBP	24 (26%)	67	0.713 (1.00)	0.709 (1.00)	0.775 (1.00)	0.406 (1.00)	1 (1.00)	0.794 (1.00)	0.94 (1.00)	1 (1.00)
SARM1	14 (15%)	77	0.0196 (1.00)	0.471 (1.00)	0.836 (1.00)	0.908 (1.00)	0.468 (1.00)	0.615 (1.00)	0.331 (1.00)	0.0591 (1.00)
ERCC2	19 (21%)	72	0.0188 (1.00)	0.229 (1.00)	0.107 (1.00)	0.00307 (1.00)	0.166 (1.00)	0.0678 (1.00)	0.077 (1.00)	0.0388 (1.00)
NEFH	10 (11%)	81	0.167 (1.00)	0.382 (1.00)	0.234 (1.00)	1 (1.00)	0.491 (1.00)	0.661 (1.00)	0.625 (1.00)	0.764 (1.00)
KBTBD13	15 (16%)	76	0.344 (1.00)	0.467 (1.00)	0.765 (1.00)	0.101 (1.00)	0.731 (1.00)	0.737 (1.00)	0.493 (1.00)	0.859 (1.00)
IRX3	21 (23%)	70	0.315 (1.00)	0.538 (1.00)	0.241 (1.00)	0.456 (1.00)	0.307 (1.00)	0.766 (1.00)	0.141 (1.00)	1 (1.00)
MUC2	18 (20%)	73	0.829 (1.00)	0.0845 (1.00)	0.098 (1.00)	0.0889 (1.00)	0.179 (1.00)	0.0271 (1.00)	0.114 (1.00)	0.0432 (1.00)
GARS	35 (38%)	56	0.284 (1.00)	0.562 (1.00)	0.548 (1.00)	0.154 (1.00)	0.173 (1.00)	0.0436 (1.00)	0.123 (1.00)	0.0908 (1.00)
UQCRFS1	12 (13%)	79	0.885 (1.00)	0.429 (1.00)	0.822 (1.00)	0.544 (1.00)	0.36 (1.00)	0.0717 (1.00)	0.328 (1.00)	0.0653 (1.00)
ATXN1	14 (15%)	77	0.661 (1.00)	0.178 (1.00)	0.677 (1.00)	0.845 (1.00)	0.833 (1.00)	0.899 (1.00)	0.917 (1.00)	0.904 (1.00)
ZNF628	10 (11%)	81	0.0739 (1.00)	0.368 (1.00)	0.0703 (1.00)	0.059 (1.00)	0.0417 (1.00)	0.446 (1.00)	0.0433 (1.00)	0.406 (1.00)
DSPP	13 (14%)	78	0.694 (1.00)	0.175 (1.00)	0.867 (1.00)	0.917 (1.00)	0.833 (1.00)	0.586 (1.00)	0.448 (1.00)	0.492 (1.00)
ASPDH	19 (21%)	72	0.289 (1.00)	0.674 (1.00)	0.0774 (1.00)	0.0874 (1.00)	0.174 (1.00)	0.00171 (1.00)	0.0539 (1.00)	0.00136 (1.00)
CSGALNACT2	5 (5%)	86	0.312 (1.00)	0.0371 (1.00)	0.626 (1.00)	0.264 (1.00)	0.125 (1.00)	0.248 (1.00)	0.186 (1.00)	0.325 (1.00)
TPO	21 (23%)	70	0.297 (1.00)	0.102 (1.00)	0.25 (1.00)	0.249 (1.00)	0.276 (1.00)	1 (1.00)	0.172 (1.00)	0.705 (1.00)
KRTAP4-5	7 (8%)	84	0.262 (1.00)	0.115 (1.00)	0.722 (1.00)	0.88 (1.00)	0.855 (1.00)	0.306 (1.00)	0.547 (1.00)	0.336 (1.00)
GLTSCR2	8 (9%)	83	0.504 (1.00)	0.173 (1.00)	0.217 (1.00)	0.711 (1.00)	0.297 (1.00)	0.216 (1.00)	0.0706 (1.00)	0.342 (1.00)
PANK2	15 (16%)	76	0.725 (1.00)	0.802 (1.00)	0.779 (1.00)	0.724 (1.00)	1 (1.00)	0.748 (1.00)	1 (1.00)	0.509 (1.00)
RNF39	7 (8%)	84	0.416 (1.00)	0.139 (1.00)	0.0334 (1.00)	0.00798 (1.00)	0.0544 (1.00)	0.64 (1.00)	0.145 (1.00)	0.645 (1.00)
MAL2	23 (25%)	68	0.275 (1.00)	0.782 (1.00)	0.0202 (1.00)	1 (1.00)	0.425 (1.00)	0.687 (1.00)	0.782 (1.00)	0.849 (1.00)
ZAR1	19 (21%)	72	0.252 (1.00)	0.634 (1.00)	0.543 (1.00)	0.602 (1.00)	0.281 (1.00)	1 (1.00)	0.542 (1.00)	0.849 (1.00)
C16ORF3	8 (9%)	83	0.734 (1.00)	0.00275 (1.00)	0.43 (1.00)	1 (1.00)	0.656 (1.00)	1 (1.00)	0.645 (1.00)	1 (1.00)
KRTAP5-5	7 (8%)	84	0.505 (1.00)	0.564 (1.00)	0.515 (1.00)	1 (1.00)	0.591 (1.00)	0.537 (1.00)	0.703 (1.00)	0.834 (1.00)
CRIPAK	17 (19%)	74	0.378 (1.00)	0.566 (1.00)	0.163 (1.00)	0.815 (1.00)	0.87 (1.00)	1 (1.00)	0.705 (1.00)	1 (1.00)
C14ORF180	4 (4%)	87	0.626 (1.00)	0.0794 (1.00)	0.537 (1.00)	0.621 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.249 (1.00)
SPERT	5 (5%)	86	0.463 (1.00)	0.592 (1.00)	0.0316 (1.00)	0.128 (1.00)	0.132 (1.00)	0.342 (1.00)	0.182 (1.00)	0.192 (1.00)
TP53	17 (19%)	74	0.0173 (1.00)	0.519 (1.00)	0.00344 (1.00)	0.115 (1.00)	0.00268 (1.00)	0.07 (1.00)	0.00936 (1.00)	0.0373 (1.00)
B3GNT6	4 (4%)	87	0.32 (1.00)
BHLHE22	10 (11%)	81	0.0312 (1.00)	0.27 (1.00)	0.00963 (1.00)	0.3 (1.00)	0.684 (1.00)	0.89 (1.00)	0.831 (1.00)	1 (1.00)
RGMB	10 (11%)	81	0.186 (1.00)	0.831 (1.00)	0.935 (1.00)	0.363 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	1 (1.00)
APOE	8 (9%)	83	0.0848 (1.00)	0.342 (1.00)	0.124 (1.00)	0.471 (1.00)	0.297 (1.00)	0.446 (1.00)	0.0706 (1.00)	0.406 (1.00)
PCGF6	4 (4%)	87	0.497 (1.00)
MEN1	8 (9%)	83	0.384 (1.00)	0.0105 (1.00)	0.165 (1.00)	0.014 (1.00)	0.491 (1.00)	0.375 (1.00)	0.625 (1.00)	0.332 (1.00)
LZTR1	7 (8%)	84	0.241 (1.00)	0.305 (1.00)	0.055 (1.00)	0.44 (1.00)	0.213 (1.00)	0.152 (1.00)	0.358 (1.00)	0.553 (1.00)
RASIP1	11 (12%)	80	0.337 (1.00)	0.735 (1.00)	0.0442 (1.00)	0.155 (1.00)	0.0118 (1.00)	0.211 (1.00)	0.00128 (1.00)	0.199 (1.00)
ZC3H12D	6 (7%)	85	0.0274 (1.00)	0.864 (1.00)	0.804 (1.00)	0.32 (1.00)	0.422 (1.00)	0.303 (1.00)	0.499 (1.00)	0.063 (1.00)
TSC22D2	11 (12%)	80	0.372 (1.00)	0.275 (1.00)	0.936 (1.00)	0.694 (1.00)	1 (1.00)	0.514 (1.00)	1 (1.00)	0.465 (1.00)
COQ2	7 (8%)	84	0.081 (1.00)	0.691 (1.00)	0.528 (1.00)	0.488 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.724 (1.00)
DLEU7	6 (7%)	85	0.218 (1.00)	0.788 (1.00)	0.536 (1.00)	0.21 (1.00)	0.409 (1.00)	1 (1.00)	0.444 (1.00)	1 (1.00)
FAM46A	4 (4%)	87	0.709 (1.00)	0.874 (1.00)	0.877 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
JMJD4	6 (7%)	85	0.634 (1.00)	0.177 (1.00)	0.331 (1.00)	0.44 (1.00)	0.846 (1.00)	0.822 (1.00)	1 (1.00)	0.834 (1.00)
DOK7	7 (8%)	84	0.609 (1.00)	0.373 (1.00)	1 (1.00)	1 (1.00)	0.882 (1.00)	0.0198 (1.00)	0.771 (1.00)	0.02 (1.00)
KNDC1	16 (18%)	75	0.775 (1.00)	0.0847 (1.00)	0.554 (1.00)	0.601 (1.00)	0.593 (1.00)	0.588 (1.00)	0.588 (1.00)	0.724 (1.00)
SIX6	3 (3%)	88	0.00409 (1.00)	0.0715 (1.00)	0.00478 (1.00)	0.0202 (1.00)	0.3 (1.00)	0.526 (1.00)	0.315 (1.00)	0.384 (1.00)
PDCD6	5 (5%)	86	0.0684 (1.00)	0.482 (1.00)	0.348 (1.00)	0.379 (1.00)	0.422 (1.00)	0.822 (1.00)	0.499 (1.00)	0.553 (1.00)
HNRNPCL1	4 (4%)	87	0.292 (1.00)
ATP6V0E2	4 (4%)	87	0.724 (1.00)	0.725 (1.00)	0.638 (1.00)	0.467 (1.00)	0.0883 (1.00)	0.435 (1.00)	0.133 (1.00)	0.455 (1.00)
HES3	7 (8%)	84	0.505 (1.00)	0.794 (1.00)	0.515 (1.00)	0.44 (1.00)	0.166 (1.00)	1 (1.00)	0.299 (1.00)	1 (1.00)
AATK	9 (10%)	82	0.518 (1.00)	0.32 (1.00)	0.725 (1.00)	0.279 (1.00)	1 (1.00)	0.862 (1.00)	1 (1.00)	0.747 (1.00)
FANK1	4 (4%)	87	0.863 (1.00)	0.496 (1.00)	0.877 (1.00)	0.781 (1.00)	0.781 (1.00)	0.229 (1.00)	0.796 (1.00)	0.249 (1.00)
FEZ2	5 (5%)	86	0.809 (1.00)	0.982 (1.00)	0.485 (1.00)	0.506 (1.00)	0.277 (1.00)	0.537 (1.00)	0.423 (1.00)	0.163 (1.00)
HSD17B1	5 (5%)	86	0.809 (1.00)	0.246 (1.00)	1 (1.00)	0.176 (1.00)	0.591 (1.00)	1 (1.00)	0.703 (1.00)	0.432 (1.00)
PRKAR1A	7 (8%)	84	0.609 (1.00)	0.794 (1.00)	0.0594 (1.00)	0.471 (1.00)	0.523 (1.00)	0.64 (1.00)	0.219 (1.00)	0.645 (1.00)
ATOH8	4 (4%)	87	0.626 (1.00)	0.7 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.229 (1.00)	1 (1.00)	0.249 (1.00)
BTBD11	9 (10%)	82	0.498 (1.00)	0.872 (1.00)	0.267 (1.00)	0.278 (1.00)	0.703 (1.00)	0.877 (1.00)	0.8 (1.00)	0.875 (1.00)
KANK3	6 (7%)	85	0.0378 (1.00)	0.532 (1.00)	0.048 (1.00)	0.0108 (1.00)	0.0573 (1.00)	1 (1.00)	0.101 (1.00)	1 (1.00)
PAQR4	3 (3%)	88	0.872 (1.00)	0.874 (1.00)	0.877 (1.00)	1 (1.00)	0.781 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
NOM1	7 (8%)	84	0.768 (1.00)	0.691 (1.00)	0.615 (1.00)	0.88 (1.00)	0.855 (1.00)	1 (1.00)	0.547 (1.00)	1 (1.00)
PLIN5	6 (7%)	85	0.152 (1.00)	0.505 (1.00)	0.888 (1.00)	0.488 (1.00)	0.326 (1.00)	0.0402 (1.00)	0.146 (1.00)	0.0391 (1.00)
CD320	5 (5%)	86	0.72 (1.00)	0.564 (1.00)	0.708 (1.00)	1 (1.00)	0.213 (1.00)	0.152 (1.00)	0.0756 (1.00)	0.128 (1.00)
AVL9	6 (7%)	85	0.25 (1.00)	0.381 (1.00)	0.908 (1.00)	0.813 (1.00)	1 (1.00)	0.591 (1.00)	1 (1.00)	0.617 (1.00)
ASB16	10 (11%)	81	0.808 (1.00)	0.947 (1.00)	0.555 (1.00)	0.88 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
SCRT1	6 (7%)	85	0.616 (1.00)	0.345 (1.00)	0.761 (1.00)	1 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.724 (1.00)
FOXQ1	4 (4%)	87	0.0765 (1.00)	0.0866 (1.00)	1 (1.00)	0.781 (1.00)	0.586 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
NPTX1	6 (7%)	85	0.101 (1.00)	0.494 (1.00)	0.615 (1.00)	0.313 (1.00)	0.398 (1.00)	0.306 (1.00)	0.399 (1.00)	0.0522 (1.00)
ZNF285	3 (3%)	88	0.526 (1.00)
PTPLA	6 (7%)	85	0.243 (1.00)	0.359 (1.00)	0.708 (1.00)	0.597 (1.00)	1 (1.00)	1 (1.00)	0.703 (1.00)	1 (1.00)
PRSS27	4 (4%)	87	0.439 (1.00)	0.592 (1.00)	0.261 (1.00)	0.128 (1.00)	0.185 (1.00)	1 (1.00)	0.254 (1.00)	1 (1.00)
LRRN4	4 (4%)	87	0.838 (1.00)	0.51 (1.00)	0.76 (1.00)	1 (1.00)	0.409 (1.00)	0.342 (1.00)	0.444 (1.00)	1 (1.00)
EP400	4 (4%)	87	0.872 (1.00)	0.725 (1.00)	0.448 (1.00)	0.684 (1.00)	1 (1.00)	0.786 (1.00)	1 (1.00)	1 (1.00)
LTK	4 (4%)	87	0.863 (1.00)
CCDC96	4 (4%)	87	0.103 (1.00)	0.592 (1.00)	1 (1.00)	0.684 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)
PCMTD1	4 (4%)	87	0.257 (1.00)	0.21 (1.00)	0.348 (1.00)	0.379 (1.00)	1 (1.00)	0.786 (1.00)	1 (1.00)	1 (1.00)
GLI3	8 (9%)	83	0.731 (1.00)	0.217 (1.00)	0.643 (1.00)	0.146 (1.00)	0.346 (1.00)	0.64 (1.00)	0.589 (1.00)	1 (1.00)
MN1	9 (10%)	82	0.767 (1.00)	0.264 (1.00)	0.882 (1.00)	0.898 (1.00)	0.393 (1.00)	0.258 (1.00)	0.267 (1.00)	0.281 (1.00)
C9ORF66	7 (8%)	84	0.51 (1.00)	0.947 (1.00)	0.761 (1.00)	0.488 (1.00)	0.563 (1.00)	1 (1.00)	0.752 (1.00)	0.724 (1.00)
MADCAM1	5 (5%)	86	0.0541 (1.00)	0.864 (1.00)	0.348 (1.00)	0.379 (1.00)	0.422 (1.00)	0.303 (1.00)	0.499 (1.00)	0.213 (1.00)
BMP8A	3 (3%)	88	0.387 (1.00)	0.661 (1.00)	1 (1.00)	0.781 (1.00)	1 (1.00)	1 (1.00)	0.597 (1.00)	0.538 (1.00)
ODF3L2	3 (3%)	88	0.872 (1.00)	0.661 (1.00)	0.775 (1.00)	0.781 (1.00)	0.781 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
QRICH2	4 (4%)	87	0.724 (1.00)	0.635 (1.00)	0.288 (1.00)	0.561 (1.00)	0.816 (1.00)	0.591 (1.00)	0.677 (1.00)	0.617 (1.00)
KRTAP10-7	5 (5%)	86	0.694 (1.00)	0.359 (1.00)	0.804 (1.00)	0.861 (1.00)	0.0163 (1.00)	0.199 (1.00)	0.0264 (1.00)	0.267 (1.00)
IDI1	5 (5%)	86	0.573 (1.00)	0.564 (1.00)	0.667 (1.00)	0.861 (1.00)	1 (1.00)	0.407 (1.00)	0.845 (1.00)	0.432 (1.00)
IER5	3 (3%)	88	0.237 (1.00)
PRR21	6 (7%)	85	0.585 (1.00)	0.684 (1.00)	0.754 (1.00)	0.728 (1.00)	1 (1.00)	0.537 (1.00)	0.845 (1.00)	0.834 (1.00)
ARRDC4	7 (8%)	84	0.465 (1.00)	0.334 (1.00)	0.329 (1.00)	0.165 (1.00)	0.563 (1.00)	0.711 (1.00)	0.752 (1.00)	0.612 (1.00)
RNF135	4 (4%)	87	0.709 (1.00)	0.344 (1.00)	0.296 (1.00)	0.621 (1.00)	0.781 (1.00)	0.703 (1.00)	0.796 (1.00)	0.72 (1.00)
DAXX	4 (4%)	87	0.0325 (1.00)	0.21 (1.00)	0.261 (1.00)	0.0362 (1.00)	0.409 (1.00)	1 (1.00)	0.444 (1.00)	1 (1.00)
VARS	8 (9%)	83	0.749 (1.00)	0.931 (1.00)	0.227 (1.00)	0.278 (1.00)	0.311 (1.00)	1 (1.00)	0.158 (1.00)	0.68 (1.00)
GPR20	4 (4%)	87	0.626 (1.00)	0.7 (1.00)	0.249 (1.00)	1 (1.00)	0.434 (1.00)	1 (1.00)	0.597 (1.00)	1 (1.00)
SAMD11	3 (3%)	88	0.433 (1.00)
DMWD	4 (4%)	87	0.254 (1.00)	0.788 (1.00)	0.38 (1.00)	0.813 (1.00)	1 (1.00)	1 (1.00)	0.254 (1.00)	1 (1.00)
KISS1R	3 (3%)	88	0.872 (1.00)
PLEC	17 (19%)	74	0.534 (1.00)	0.75 (1.00)	0.222 (1.00)	0.76 (1.00)	0.689 (1.00)	0.537 (1.00)	1 (1.00)	0.634 (1.00)
FAM110C	3 (3%)	88	0.723 (1.00)	0.7 (1.00)	0.465 (1.00)	0.468 (1.00)	1 (1.00)	0.229 (1.00)	1 (1.00)	0.249 (1.00)
RCCD1	5 (5%)	86	0.694 (1.00)	0.371 (1.00)	0.403 (1.00)	0.621 (1.00)	0.781 (1.00)	1 (1.00)	0.796 (1.00)	0.538 (1.00)

'CLIC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.933 (Chi-square test), Q value = 1

Table S1. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CLIC6 MUTATED	5	3	1	1	1
CLIC6 WILD-TYPE	27	20	14	9	8

'CLIC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.862 (Chi-square test), Q value = 1

Table S2. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CLIC6 MUTATED	1	1	2	3	1
CLIC6 WILD-TYPE	17	10	19	15	10

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CLIC6 MUTATED	2	2	0	4
CLIC6 WILD-TYPE	22	12	17	19

'CLIC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CLIC6 MUTATED	2	4	2
CLIC6 WILD-TYPE	21	29	20

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CLIC6 MUTATED	2	3	3
CLIC6 WILD-TYPE	35	13	23

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CLIC6 MUTATED	3	2	3
CLIC6 WILD-TYPE	23	8	40

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CLIC6 MUTATED	2	3	3
CLIC6 WILD-TYPE	36	15	20

'CLIC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'CLIC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CLIC6 MUTATED	3	2	3
CLIC6 WILD-TYPE	38	9	24

'NMU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.151 (Chi-square test), Q value = 1

Table S9. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NMU MUTATED	3	2	4	0	0
NMU WILD-TYPE	29	21	11	10	9

'NMU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.442 (Chi-square test), Q value = 1

Table S10. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NMU MUTATED	1	2	4	2	0
NMU WILD-TYPE	17	9	17	16	11

'NMU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NMU MUTATED	1	4	1	2
NMU WILD-TYPE	23	10	16	21

'NMU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NMU MUTATED	1	2	5
NMU WILD-TYPE	22	31	17

'NMU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NMU MUTATED	7	1	1
NMU WILD-TYPE	30	15	25

'NMU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NMU MUTATED	2	0	7
NMU WILD-TYPE	24	10	36

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NMU MUTATED	7	1	1
NMU WILD-TYPE	31	17	22

'NMU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'NMU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NMU MUTATED	6	1	2
NMU WILD-TYPE	35	10	25

'LPPR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Chi-square test), Q value = 1

Table S17. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LPPR2 MUTATED	1	1	2	1	1
LPPR2 WILD-TYPE	31	22	13	9	8

'LPPR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.559 (Chi-square test), Q value = 1

Table S18. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LPPR2 MUTATED	0	1	3	1	1
LPPR2 WILD-TYPE	18	10	18	17	10

'LPPR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 1

Table S19. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LPPR2 MUTATED	0	1	2	3
LPPR2 WILD-TYPE	24	13	15	20

'LPPR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 1

Table S20. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LPPR2 MUTATED	0	3	3
LPPR2 WILD-TYPE	23	30	19

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LPPR2 MUTATED	4	0	2
LPPR2 WILD-TYPE	33	16	24

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LPPR2 MUTATED	1	1	4
LPPR2 WILD-TYPE	25	9	39

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LPPR2 MUTATED	4	0	2
LPPR2 WILD-TYPE	34	18	21

'LPPR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'LPPR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LPPR2 MUTATED	3	2	1
LPPR2 WILD-TYPE	38	9	26

'CHDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Chi-square test), Q value = 1

Table S25. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CHDH MUTATED	1	0	3	1	1
CHDH WILD-TYPE	31	23	12	9	8

'CHDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.193 (Chi-square test), Q value = 1

Table S26. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CHDH MUTATED	0	1	3	0	2
CHDH WILD-TYPE	18	10	18	18	9

'CHDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S27. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CHDH MUTATED	1	1	2	2
CHDH WILD-TYPE	23	13	15	21

'CHDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S28. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CHDH MUTATED	1	2	3
CHDH WILD-TYPE	22	31	19

'CHDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S29. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	34	15	24

'CHDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S30. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CHDH MUTATED	2	1	3
CHDH WILD-TYPE	24	9	40

'CHDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	35	17	21

'CHDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'CHDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CHDH MUTATED	3	1	2
CHDH WILD-TYPE	38	10	25

'C4ORF32 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S33. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C4ORF32 MUTATED	4	1	2	1	1
C4ORF32 WILD-TYPE	28	22	13	9	8

'C4ORF32 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S34. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C4ORF32 MUTATED	3	0	1	1	1
C4ORF32 WILD-TYPE	15	11	20	17	10

'C4ORF32 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S35. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C4ORF32 MUTATED	4	1	1	0
C4ORF32 WILD-TYPE	20	13	16	23

'C4ORF32 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S36. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C4ORF32 MUTATED	3	2	1
C4ORF32 WILD-TYPE	20	31	21

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S37. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C4ORF32 MUTATED	3	2	1
C4ORF32 WILD-TYPE	34	14	25

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S38. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C4ORF32 MUTATED	2	0	4
C4ORF32 WILD-TYPE	24	10	39

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S39. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C4ORF32 MUTATED	3	3	0
C4ORF32 WILD-TYPE	35	15	23

'C4ORF32 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'C4ORF32 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C4ORF32 MUTATED	3	0	3
C4ORF32 WILD-TYPE	38	11	24

'SYT8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.897 (Chi-square test), Q value = 1

Table S41. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SYT8 MUTATED	5	5	2	1	1
SYT8 WILD-TYPE	27	18	13	9	8

'SYT8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.555 (Chi-square test), Q value = 1

Table S42. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SYT8 MUTATED	1	3	3	3	1
SYT8 WILD-TYPE	17	8	18	15	10

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S43. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SYT8 MUTATED	2	3	2	4
SYT8 WILD-TYPE	22	11	15	19

'SYT8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S44. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SYT8 MUTATED	2	5	4
SYT8 WILD-TYPE	21	28	18

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S45. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SYT8 MUTATED	5	2	4
SYT8 WILD-TYPE	32	14	22

'SYT8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S46. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SYT8 MUTATED	4	2	5
SYT8 WILD-TYPE	22	8	38

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S47. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SYT8 MUTATED	5	2	4
SYT8 WILD-TYPE	33	16	19

'SYT8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S48. Gene #6: 'SYT8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SYT8 MUTATED	4	3	4
SYT8 WILD-TYPE	37	8	23

'RINL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0471 (Chi-square test), Q value = 1

Table S49. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RINL MUTATED	12	2	3	2	0
RINL WILD-TYPE	20	21	12	8	9

Figure S1. Get High-res Image Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'RINL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.567 (Chi-square test), Q value = 1

Table S50. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RINL MUTATED	6	2	4	3	1
RINL WILD-TYPE	12	9	17	15	10

'RINL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S51. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RINL MUTATED	8	4	2	2
RINL WILD-TYPE	16	10	15	21

'RINL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S52. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RINL MUTATED	8	4	4
RINL WILD-TYPE	15	29	18

'RINL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S53. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RINL MUTATED	9	4	3
RINL WILD-TYPE	28	12	23

'RINL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S54. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RINL MUTATED	5	1	10
RINL WILD-TYPE	21	9	33

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S55. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RINL MUTATED	9	5	2
RINL WILD-TYPE	29	13	21

'RINL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S56. Gene #7: 'RINL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RINL MUTATED	8	2	6
RINL WILD-TYPE	33	9	21

'OBSCN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.527 (Chi-square test), Q value = 1

Table S57. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
OBSCN MUTATED	12	8	2	4	3
OBSCN WILD-TYPE	20	15	13	6	6

'OBSCN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S58. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
OBSCN MUTATED	5	6	5	6	4
OBSCN WILD-TYPE	13	5	16	12	7

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S59. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
OBSCN MUTATED	10	3	8	5
OBSCN WILD-TYPE	14	11	9	18

'OBSCN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S60. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
OBSCN MUTATED	8	12	6
OBSCN WILD-TYPE	15	21	16

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S61. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
OBSCN MUTATED	10	8	8
OBSCN WILD-TYPE	27	8	18

'OBSCN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S62. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
OBSCN MUTATED	10	3	13
OBSCN WILD-TYPE	16	7	30

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S63. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
OBSCN MUTATED	10	9	7
OBSCN WILD-TYPE	28	9	16

'OBSCN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S64. Gene #8: 'OBSCN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
OBSCN MUTATED	12	3	11
OBSCN WILD-TYPE	29	8	16

'MAP1S MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Chi-square test), Q value = 1

Table S65. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MAP1S MUTATED	1	2	3	1	2
MAP1S WILD-TYPE	31	21	12	9	7

'MAP1S MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.254 (Chi-square test), Q value = 1

Table S66. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MAP1S MUTATED	1	3	2	3	0
MAP1S WILD-TYPE	17	8	19	15	11

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S67. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MAP1S MUTATED	2	3	0	4
MAP1S WILD-TYPE	22	11	17	19

'MAP1S MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S68. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MAP1S MUTATED	3	4	2
MAP1S WILD-TYPE	20	29	20

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S69. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MAP1S MUTATED	5	1	3
MAP1S WILD-TYPE	32	15	23

'MAP1S MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S70. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MAP1S MUTATED	2	1	6
MAP1S WILD-TYPE	24	9	37

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S71. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MAP1S MUTATED	5	1	3
MAP1S WILD-TYPE	33	17	20

'MAP1S MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S72. Gene #9: 'MAP1S MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MAP1S MUTATED	6	1	2
MAP1S WILD-TYPE	35	10	25

'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.576 (Chi-square test), Q value = 1

Table S73. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GPRIN2 MUTATED	3	3	3	2	0
GPRIN2 WILD-TYPE	29	20	12	8	9

'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.746 (Chi-square test), Q value = 1

Table S74. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GPRIN2 MUTATED	2	1	4	1	1
GPRIN2 WILD-TYPE	16	10	17	17	10

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S75. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GPRIN2 MUTATED	2	2	3	2
GPRIN2 WILD-TYPE	22	12	14	21

'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S76. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GPRIN2 MUTATED	2	2	5
GPRIN2 WILD-TYPE	21	31	17

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S77. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GPRIN2 MUTATED	3	3	3
GPRIN2 WILD-TYPE	34	13	23

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.275 (Fisher's exact test), Q value = 1

Table S78. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GPRIN2 MUTATED	5	1	3
GPRIN2 WILD-TYPE	21	9	40

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S79. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GPRIN2 MUTATED	3	4	2
GPRIN2 WILD-TYPE	35	14	21

'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S80. Gene #10: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GPRIN2 MUTATED	3	1	5
GPRIN2 WILD-TYPE	38	10	22

'ATP9B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.853 (Chi-square test), Q value = 1

Table S81. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATP9B MUTATED	1	1	1	1	1
ATP9B WILD-TYPE	31	22	14	9	8

'ATP9B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Chi-square test), Q value = 1

Table S82. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATP9B MUTATED	0	1	3	0	1
ATP9B WILD-TYPE	18	10	18	18	10

'ATP9B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S83. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATP9B MUTATED	1	1	2	1
ATP9B WILD-TYPE	23	13	15	22

'ATP9B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S84. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATP9B MUTATED	1	2	2
ATP9B WILD-TYPE	22	31	20

'ATP9B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S85. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATP9B MUTATED	2	1	2
ATP9B WILD-TYPE	35	15	24

'ATP9B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S86. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATP9B MUTATED	2	0	3
ATP9B WILD-TYPE	24	10	40

'ATP9B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S87. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATP9B MUTATED	2	2	1
ATP9B WILD-TYPE	36	16	22

'ATP9B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S88. Gene #11: 'ATP9B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATP9B MUTATED	3	0	2
ATP9B WILD-TYPE	38	11	25

'RREB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0932 (Chi-square test), Q value = 1

Table S89. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RREB1 MUTATED	8	1	1	0	1
RREB1 WILD-TYPE	24	22	14	10	8

'RREB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Chi-square test), Q value = 1

Table S90. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RREB1 MUTATED	3	2	1	1	1
RREB1 WILD-TYPE	15	9	20	17	10

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S91. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RREB1 MUTATED	4	1	1	1
RREB1 WILD-TYPE	20	13	16	22

'RREB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S92. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RREB1 MUTATED	4	2	1
RREB1 WILD-TYPE	19	31	21

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S93. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RREB1 MUTATED	4	1	3
RREB1 WILD-TYPE	33	15	23

'RREB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S94. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RREB1 MUTATED	2	2	4
RREB1 WILD-TYPE	24	8	39

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S95. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RREB1 MUTATED	4	1	3
RREB1 WILD-TYPE	34	17	20

'RREB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S96. Gene #12: 'RREB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RREB1 MUTATED	4	2	2
RREB1 WILD-TYPE	37	9	25

'IDUA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.25 (Chi-square test), Q value = 1

Table S97. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IDUA MUTATED	9	2	1	2	1
IDUA WILD-TYPE	23	21	14	8	8

'IDUA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.517 (Chi-square test), Q value = 1

Table S98. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IDUA MUTATED	4	1	4	3	0
IDUA WILD-TYPE	14	10	17	15	11

'IDUA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S99. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IDUA MUTATED	6	2	2	2
IDUA WILD-TYPE	18	12	15	21

'IDUA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S100. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IDUA MUTATED	5	4	3
IDUA WILD-TYPE	18	29	19

'IDUA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S101. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IDUA MUTATED	5	5	2
IDUA WILD-TYPE	32	11	24

'IDUA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S102. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IDUA MUTATED	4	1	7
IDUA WILD-TYPE	22	9	36

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S103. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IDUA MUTATED	5	5	2
IDUA WILD-TYPE	33	13	21

'IDUA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S104. Gene #13: 'IDUA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IDUA MUTATED	6	2	4
IDUA WILD-TYPE	35	9	23

'RGS9BP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.351 (Chi-square test), Q value = 1

Table S105. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RGS9BP MUTATED	3	3	2	3	0
RGS9BP WILD-TYPE	29	20	13	7	9

'RGS9BP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.715 (Chi-square test), Q value = 1

Table S106. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RGS9BP MUTATED	3	1	4	1	1
RGS9BP WILD-TYPE	15	10	17	17	10

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S107. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RGS9BP MUTATED	3	1	2	3
RGS9BP WILD-TYPE	21	13	15	20

'RGS9BP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S108. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RGS9BP MUTATED	3	3	3
RGS9BP WILD-TYPE	20	30	19

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S109. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RGS9BP MUTATED	3	3	4
RGS9BP WILD-TYPE	34	13	22

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S110. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RGS9BP MUTATED	3	2	5
RGS9BP WILD-TYPE	23	8	38

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S111. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RGS9BP MUTATED	4	2	4
RGS9BP WILD-TYPE	34	16	19

'RGS9BP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S112. Gene #14: 'RGS9BP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RGS9BP MUTATED	5	2	3
RGS9BP WILD-TYPE	36	9	24

'WDR34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.753 (Chi-square test), Q value = 1

Table S113. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
WDR34 MUTATED	3	2	2	2	2
WDR34 WILD-TYPE	29	21	13	8	7

'WDR34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Chi-square test), Q value = 1

Table S114. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
WDR34 MUTATED	2	2	3	1	2
WDR34 WILD-TYPE	16	9	18	17	9

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S115. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
WDR34 MUTATED	4	1	2	3
WDR34 WILD-TYPE	20	13	15	20

'WDR34 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S116. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
WDR34 MUTATED	4	3	3
WDR34 WILD-TYPE	19	30	19

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S117. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
WDR34 MUTATED	6	2	2
WDR34 WILD-TYPE	31	14	24

'WDR34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S118. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
WDR34 MUTATED	1	2	7
WDR34 WILD-TYPE	25	8	36

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S119. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
WDR34 MUTATED	6	2	2
WDR34 WILD-TYPE	32	16	21

'WDR34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S120. Gene #15: 'WDR34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
WDR34 MUTATED	7	2	1
WDR34 WILD-TYPE	34	9	26

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S121. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOTCH2 MUTATED	7	1	1	2	1
NOTCH2 WILD-TYPE	25	22	14	8	8

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.573 (Chi-square test), Q value = 1

Table S122. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOTCH2 MUTATED	1	1	3	3	0
NOTCH2 WILD-TYPE	17	10	18	15	11

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S123. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOTCH2 MUTATED	3	1	2	2
NOTCH2 WILD-TYPE	21	13	15	21

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S124. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOTCH2 MUTATED	1	4	3
NOTCH2 WILD-TYPE	22	29	19

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S125. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOTCH2 MUTATED	3	4	1
NOTCH2 WILD-TYPE	34	12	25

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S126. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOTCH2 MUTATED	2	1	5
NOTCH2 WILD-TYPE	24	9	38

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S127. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOTCH2 MUTATED	3	4	1
NOTCH2 WILD-TYPE	35	14	22

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S128. Gene #16: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOTCH2 MUTATED	3	2	3
NOTCH2 WILD-TYPE	38	9	24

'TMEM189 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Chi-square test), Q value = 1

Table S129. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TMEM189 MUTATED	6	1	2	3	0
TMEM189 WILD-TYPE	26	22	13	7	9

'TMEM189 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.854 (Chi-square test), Q value = 1

Table S130. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TMEM189 MUTATED	2	2	3	1	1
TMEM189 WILD-TYPE	16	9	18	17	10

'TMEM189 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S131. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TMEM189 MUTATED	4	3	1	1
TMEM189 WILD-TYPE	20	11	16	22

'TMEM189 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0878 (Fisher's exact test), Q value = 1

Table S132. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TMEM189 MUTATED	5	1	3
TMEM189 WILD-TYPE	18	32	19

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S133. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TMEM189 MUTATED	5	3	1
TMEM189 WILD-TYPE	32	13	25

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S134. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TMEM189 MUTATED	3	0	6
TMEM189 WILD-TYPE	23	10	37

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S135. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TMEM189 MUTATED	5	3	1
TMEM189 WILD-TYPE	33	15	22

'TMEM189 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S136. Gene #17: 'TMEM189 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TMEM189 MUTATED	6	0	3
TMEM189 WILD-TYPE	35	11	24

'TAF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.408 (Chi-square test), Q value = 1

Table S137. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TAF5 MUTATED	7	2	2	0	1
TAF5 WILD-TYPE	25	21	13	10	8

'TAF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.666 (Chi-square test), Q value = 1

Table S138. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TAF5 MUTATED	2	3	2	2	2
TAF5 WILD-TYPE	16	8	19	16	9

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S139. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TAF5 MUTATED	4	2	2	3
TAF5 WILD-TYPE	20	12	15	20

'TAF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S140. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TAF5 MUTATED	5	4	2
TAF5 WILD-TYPE	18	29	20

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S141. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TAF5 MUTATED	4	4	3
TAF5 WILD-TYPE	33	12	23

'TAF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0703 (Fisher's exact test), Q value = 1

Table S142. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TAF5 MUTATED	7	0	4
TAF5 WILD-TYPE	19	10	39

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 1

Table S143. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TAF5 MUTATED	4	5	2
TAF5 WILD-TYPE	34	13	21

'TAF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.11 (Fisher's exact test), Q value = 1

Table S144. Gene #18: 'TAF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TAF5 MUTATED	3	1	7
TAF5 WILD-TYPE	38	10	20

'LRP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00701 (Chi-square test), Q value = 1

Table S145. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRP11 MUTATED	1	2	1	4	0
LRP11 WILD-TYPE	31	21	14	6	9

Figure S2. Get High-res Image Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'LRP11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.373 (Chi-square test), Q value = 1

Table S146. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRP11 MUTATED	1	0	4	1	1
LRP11 WILD-TYPE	17	11	17	17	10

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S147. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRP11 MUTATED	2	1	2	2
LRP11 WILD-TYPE	22	13	15	21

'LRP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S148. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRP11 MUTATED	2	2	3
LRP11 WILD-TYPE	21	31	19

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S149. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRP11 MUTATED	4	2	1
LRP11 WILD-TYPE	33	14	25

'LRP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S150. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRP11 MUTATED	2	0	5
LRP11 WILD-TYPE	24	10	38

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S151. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRP11 MUTATED	4	2	1
LRP11 WILD-TYPE	34	16	22

'LRP11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S152. Gene #19: 'LRP11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRP11 MUTATED	4	1	2
LRP11 WILD-TYPE	37	10	25

'FPGS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Chi-square test), Q value = 1

Table S153. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FPGS MUTATED	2	4	4	3	1
FPGS WILD-TYPE	30	19	11	7	8

'FPGS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.515 (Chi-square test), Q value = 1

Table S154. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FPGS MUTATED	1	1	5	2	2
FPGS WILD-TYPE	17	10	16	16	9

'FPGS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0636 (Fisher's exact test), Q value = 1

Table S155. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FPGS MUTATED	2	4	0	5
FPGS WILD-TYPE	22	10	17	18

'FPGS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S156. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FPGS MUTATED	3	5	3
FPGS WILD-TYPE	20	28	19

'FPGS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S157. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FPGS MUTATED	4	2	5
FPGS WILD-TYPE	33	14	21

'FPGS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S158. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FPGS MUTATED	4	1	6
FPGS WILD-TYPE	22	9	37

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S159. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FPGS MUTATED	5	1	5
FPGS WILD-TYPE	33	17	18

'FPGS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S160. Gene #20: 'FPGS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FPGS MUTATED	6	1	4
FPGS WILD-TYPE	35	10	23

'BAG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.956 (Chi-square test), Q value = 1

Table S161. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BAG1 MUTATED	2	1	1	1	1
BAG1 WILD-TYPE	30	22	14	9	8

'BAG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S162. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BAG1 MUTATED	1	0	3	0	1
BAG1 WILD-TYPE	17	11	18	18	10

'BAG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S163. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BAG1 MUTATED	1	0	2	2
BAG1 WILD-TYPE	23	14	15	21

'BAG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S164. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BAG1 MUTATED	1	3	1
BAG1 WILD-TYPE	22	30	21

'BAG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S165. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BAG1 MUTATED	1	1	3
BAG1 WILD-TYPE	36	15	23

'BAG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0804 (Fisher's exact test), Q value = 1

Table S166. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BAG1 MUTATED	2	2	1
BAG1 WILD-TYPE	24	8	42

'BAG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S167. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BAG1 MUTATED	1	1	3
BAG1 WILD-TYPE	37	17	20

'BAG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S168. Gene #21: 'BAG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BAG1 MUTATED	1	2	2
BAG1 WILD-TYPE	40	9	25

'FZD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.424 (Chi-square test), Q value = 1

Table S169. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FZD1 MUTATED	3	0	2	1	0
FZD1 WILD-TYPE	29	23	13	9	9

'FZD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S170. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FZD1 MUTATED	0	1	2	0	0
FZD1 WILD-TYPE	18	10	19	18	11

'FZD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S171. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FZD1 MUTATED	1	1	1	0
FZD1 WILD-TYPE	23	13	16	23

'FZD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S172. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FZD1 MUTATED	1	0	2
FZD1 WILD-TYPE	22	33	20

'FZD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S173. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	34	16	26

'FZD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S174. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FZD1 MUTATED	0	0	3
FZD1 WILD-TYPE	26	10	40

'FZD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S175. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	35	18	23

'FZD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S176. Gene #22: 'FZD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FZD1 MUTATED	3	0	0
FZD1 WILD-TYPE	38	11	27

'TOR3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.674 (Chi-square test), Q value = 1

Table S177. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TOR3A MUTATED	10	4	4	4	2
TOR3A WILD-TYPE	22	19	11	6	7

'TOR3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0628 (Chi-square test), Q value = 1

Table S178. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TOR3A MUTATED	3	0	8	8	3
TOR3A WILD-TYPE	15	11	13	10	8

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S179. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TOR3A MUTATED	4	4	6	8
TOR3A WILD-TYPE	20	10	11	15

'TOR3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0295 (Fisher's exact test), Q value = 1

Table S180. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TOR3A MUTATED	2	13	7
TOR3A WILD-TYPE	21	20	15

Figure S3. Get High-res Image Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S181. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TOR3A MUTATED	10	4	8
TOR3A WILD-TYPE	27	12	18

'TOR3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 1

Table S182. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TOR3A MUTATED	10	1	11
TOR3A WILD-TYPE	16	9	32

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S183. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TOR3A MUTATED	10	5	7
TOR3A WILD-TYPE	28	13	16

'TOR3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S184. Gene #23: 'TOR3A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TOR3A MUTATED	10	2	10
TOR3A WILD-TYPE	31	9	17

'TMEM200C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.652 (Chi-square test), Q value = 1

Table S185. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TMEM200C MUTATED	3	0	1	1	1
TMEM200C WILD-TYPE	29	23	14	9	8

'TMEM200C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S186. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TMEM200C MUTATED	0	0	2	0	1
TMEM200C WILD-TYPE	18	11	19	18	10

'TMEM200C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0137 (Fisher's exact test), Q value = 1

Table S187. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TMEM200C MUTATED	0	0	3	0
TMEM200C WILD-TYPE	24	14	14	23

Figure S4. Get High-res Image Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TMEM200C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S188. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TMEM200C MUTATED	0	1	2
TMEM200C WILD-TYPE	23	32	20

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S189. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TMEM200C MUTATED	2	0	1
TMEM200C WILD-TYPE	35	16	25

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S190. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TMEM200C MUTATED	1	0	2
TMEM200C WILD-TYPE	25	10	41

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S191. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TMEM200C MUTATED	2	1	0
TMEM200C WILD-TYPE	36	17	23

'TMEM200C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S192. Gene #24: 'TMEM200C MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TMEM200C MUTATED	2	0	1
TMEM200C WILD-TYPE	39	11	26

'ZNF517 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.59 (Chi-square test), Q value = 1

Table S193. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF517 MUTATED	14	9	6	2	2
ZNF517 WILD-TYPE	18	14	9	8	7

'ZNF517 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Chi-square test), Q value = 1

Table S194. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF517 MUTATED	7	3	7	6	3
ZNF517 WILD-TYPE	11	8	14	12	8

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S195. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF517 MUTATED	9	6	5	6
ZNF517 WILD-TYPE	15	8	12	17

'ZNF517 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S196. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF517 MUTATED	8	10	8
ZNF517 WILD-TYPE	15	23	14

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S197. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF517 MUTATED	12	7	7
ZNF517 WILD-TYPE	25	9	19

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S198. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF517 MUTATED	9	3	14
ZNF517 WILD-TYPE	17	7	29

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S199. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF517 MUTATED	13	7	6
ZNF517 WILD-TYPE	25	11	17

'ZNF517 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S200. Gene #25: 'ZNF517 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF517 MUTATED	13	4	9
ZNF517 WILD-TYPE	28	7	18

'DMRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.635 (Chi-square test), Q value = 1

Table S201. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMRT1 MUTATED	1	2	0	1	1
DMRT1 WILD-TYPE	31	21	15	9	8

'DMRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.24 (Chi-square test), Q value = 1

Table S202. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMRT1 MUTATED	0	0	1	1	2
DMRT1 WILD-TYPE	18	11	20	17	9

'DMRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S203. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMRT1 MUTATED	0	0	2	2
DMRT1 WILD-TYPE	24	14	15	21

'DMRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0922 (Fisher's exact test), Q value = 1

Table S204. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMRT1 MUTATED	0	4	0
DMRT1 WILD-TYPE	23	29	22

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0209 (Fisher's exact test), Q value = 1

Table S205. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMRT1 MUTATED	0	0	4
DMRT1 WILD-TYPE	37	16	22

Figure S5. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00222 (Fisher's exact test), Q value = 1

Table S206. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMRT1 MUTATED	1	3	0
DMRT1 WILD-TYPE	25	7	43

Figure S6. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0623 (Fisher's exact test), Q value = 1

Table S207. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMRT1 MUTATED	0	1	3
DMRT1 WILD-TYPE	38	17	20

'DMRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00318 (Fisher's exact test), Q value = 1

Table S208. Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMRT1 MUTATED	0	3	1
DMRT1 WILD-TYPE	41	8	26

Figure S7. Get High-res Image Gene #26: 'DMRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GLTPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.339 (Chi-square test), Q value = 1

Table S209. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLTPD2 MUTATED	7	2	4	4	2
GLTPD2 WILD-TYPE	25	21	11	6	7

'GLTPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.962 (Chi-square test), Q value = 1

Table S210. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLTPD2 MUTATED	3	2	5	4	3
GLTPD2 WILD-TYPE	15	9	16	14	8

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.955 (Fisher's exact test), Q value = 1

Table S211. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLTPD2 MUTATED	6	3	3	5
GLTPD2 WILD-TYPE	18	11	14	18

'GLTPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S212. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLTPD2 MUTATED	5	6	6
GLTPD2 WILD-TYPE	18	27	16

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S213. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLTPD2 MUTATED	8	5	4
GLTPD2 WILD-TYPE	29	11	22

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S214. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLTPD2 MUTATED	4	3	10
GLTPD2 WILD-TYPE	22	7	33

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S215. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLTPD2 MUTATED	8	5	4
GLTPD2 WILD-TYPE	30	13	19

'GLTPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S216. Gene #27: 'GLTPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLTPD2 MUTATED	9	3	5
GLTPD2 WILD-TYPE	32	8	22

'SEMA5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Chi-square test), Q value = 1

Table S217. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SEMA5B MUTATED	10	2	2	1	1
SEMA5B WILD-TYPE	22	21	13	9	8

'SEMA5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.637 (Chi-square test), Q value = 1

Table S218. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SEMA5B MUTATED	4	1	2	4	1
SEMA5B WILD-TYPE	14	10	19	14	10

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S219. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SEMA5B MUTATED	6	3	0	3
SEMA5B WILD-TYPE	18	11	17	20

'SEMA5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S220. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SEMA5B MUTATED	6	4	2
SEMA5B WILD-TYPE	17	29	20

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S221. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SEMA5B MUTATED	6	3	3
SEMA5B WILD-TYPE	31	13	23

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S222. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SEMA5B MUTATED	5	1	6
SEMA5B WILD-TYPE	21	9	37

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S223. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SEMA5B MUTATED	6	3	3
SEMA5B WILD-TYPE	32	15	20

'SEMA5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S224. Gene #28: 'SEMA5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SEMA5B MUTATED	6	1	5
SEMA5B WILD-TYPE	35	10	22

'TNIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.589 (Chi-square test), Q value = 1

Table S225. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TNIP2 MUTATED	4	1	0	1	1
TNIP2 WILD-TYPE	28	22	15	9	8

'TNIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.293 (Chi-square test), Q value = 1

Table S226. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TNIP2 MUTATED	1	2	2	0	0
TNIP2 WILD-TYPE	17	9	19	18	11

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S227. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TNIP2 MUTATED	2	0	2	1
TNIP2 WILD-TYPE	22	14	15	22

'TNIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S228. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TNIP2 MUTATED	2	1	2
TNIP2 WILD-TYPE	21	32	20

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S229. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TNIP2 MUTATED	3	1	1
TNIP2 WILD-TYPE	34	15	25

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S230. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TNIP2 MUTATED	0	1	4
TNIP2 WILD-TYPE	26	9	39

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TNIP2 MUTATED	3	1	1
TNIP2 WILD-TYPE	35	17	22

'TNIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S232. Gene #29: 'TNIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TNIP2 MUTATED	4	1	0
TNIP2 WILD-TYPE	37	10	27

'HHIPL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.134 (Chi-square test), Q value = 1

Table S233. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HHIPL1 MUTATED	6	1	4	3	0
HHIPL1 WILD-TYPE	26	22	11	7	9

'HHIPL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.961 (Chi-square test), Q value = 1

Table S234. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HHIPL1 MUTATED	2	1	3	3	2
HHIPL1 WILD-TYPE	16	10	18	15	9

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S235. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HHIPL1 MUTATED	5	3	2	1
HHIPL1 WILD-TYPE	19	11	15	22

'HHIPL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S236. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HHIPL1 MUTATED	3	4	4
HHIPL1 WILD-TYPE	20	29	18

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0149 (Fisher's exact test), Q value = 1

Table S237. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HHIPL1 MUTATED	9	2	0
HHIPL1 WILD-TYPE	28	14	26

Figure S8. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0376 (Fisher's exact test), Q value = 1

Table S238. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HHIPL1 MUTATED	1	0	10
HHIPL1 WILD-TYPE	25	10	33

Figure S9. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S239. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HHIPL1 MUTATED	9	2	0
HHIPL1 WILD-TYPE	29	16	23

Figure S10. Get High-res Image Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'HHIPL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S240. Gene #30: 'HHIPL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HHIPL1 MUTATED	9	0	2
HHIPL1 WILD-TYPE	32	11	25

'HECTD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.746 (Chi-square test), Q value = 1

Table S241. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HECTD2 MUTATED	3	1	2	1	0
HECTD2 WILD-TYPE	29	22	13	9	9

'HECTD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Chi-square test), Q value = 1

Table S242. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HECTD2 MUTATED	3	0	2	1	0
HECTD2 WILD-TYPE	15	11	19	17	11

'HECTD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S243. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HECTD2 MUTATED	3	2	0	1
HECTD2 WILD-TYPE	21	12	17	22

'HECTD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.415 (Fisher's exact test), Q value = 1

Table S244. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HECTD2 MUTATED	3	1	2
HECTD2 WILD-TYPE	20	32	20

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S245. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HECTD2 MUTATED	3	2	1
HECTD2 WILD-TYPE	34	14	25

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S246. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HECTD2 MUTATED	2	1	3
HECTD2 WILD-TYPE	24	9	40

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S247. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HECTD2 MUTATED	3	2	1
HECTD2 WILD-TYPE	35	16	22

'HECTD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S248. Gene #31: 'HECTD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HECTD2 MUTATED	3	1	2
HECTD2 WILD-TYPE	38	10	25

'ADAD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Chi-square test), Q value = 1

Table S249. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ADAD2 MUTATED	5	1	5	3	1
ADAD2 WILD-TYPE	27	22	10	7	8

'ADAD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.141 (Chi-square test), Q value = 1

Table S250. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ADAD2 MUTATED	1	0	6	3	3
ADAD2 WILD-TYPE	17	11	15	15	8

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S251. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ADAD2 MUTATED	3	3	3	4
ADAD2 WILD-TYPE	21	11	14	19

'ADAD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S252. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ADAD2 MUTATED	2	5	6
ADAD2 WILD-TYPE	21	28	16

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S253. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ADAD2 MUTATED	5	4	4
ADAD2 WILD-TYPE	32	12	22

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S254. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ADAD2 MUTATED	6	1	6
ADAD2 WILD-TYPE	20	9	37

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S255. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ADAD2 MUTATED	5	4	4
ADAD2 WILD-TYPE	33	14	19

'ADAD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S256. Gene #32: 'ADAD2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ADAD2 MUTATED	6	1	6
ADAD2 WILD-TYPE	35	10	21

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.435 (Chi-square test), Q value = 1

Table S257. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CTNNB1 MUTATED	7	2	3	2	0
CTNNB1 WILD-TYPE	25	21	12	8	9

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0574 (Chi-square test), Q value = 1

Table S258. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CTNNB1 MUTATED	5	4	2	0	2
CTNNB1 WILD-TYPE	13	7	19	18	9

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.000193 (Fisher's exact test), Q value = 0.22

Table S259. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CTNNB1 MUTATED	8	5	0	0
CTNNB1 WILD-TYPE	16	9	17	23

Figure S11. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 3.12e-05 (Fisher's exact test), Q value = 0.036

Table S260. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CTNNB1 MUTATED	10	0	3
CTNNB1 WILD-TYPE	13	33	19

Figure S12. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.000643 (Fisher's exact test), Q value = 0.74

Table S261. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CTNNB1 MUTATED	6	7	0
CTNNB1 WILD-TYPE	31	9	26

Figure S13. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S262. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CTNNB1 MUTATED	4	0	9
CTNNB1 WILD-TYPE	22	10	34

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00645 (Fisher's exact test), Q value = 1

Table S263. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CTNNB1 MUTATED	7	6	0
CTNNB1 WILD-TYPE	31	12	23

Figure S14. Get High-res Image Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.251 (Fisher's exact test), Q value = 1

Table S264. Gene #33: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CTNNB1 MUTATED	9	0	4
CTNNB1 WILD-TYPE	32	11	23

'ZFPM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.225 (Chi-square test), Q value = 1

Table S265. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZFPM1 MUTATED	19	10	8	8	3
ZFPM1 WILD-TYPE	13	13	7	2	6

'ZFPM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.903 (Chi-square test), Q value = 1

Table S266. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZFPM1 MUTATED	10	6	9	10	5
ZFPM1 WILD-TYPE	8	5	12	8	6

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S267. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZFPM1 MUTATED	13	6	9	12
ZFPM1 WILD-TYPE	11	8	8	11

'ZFPM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S268. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZFPM1 MUTATED	13	16	11
ZFPM1 WILD-TYPE	10	17	11

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S269. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZFPM1 MUTATED	19	9	12
ZFPM1 WILD-TYPE	18	7	14

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S270. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZFPM1 MUTATED	16	3	21
ZFPM1 WILD-TYPE	10	7	22

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S271. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZFPM1 MUTATED	19	11	10
ZFPM1 WILD-TYPE	19	7	13

'ZFPM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S272. Gene #34: 'ZFPM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZFPM1 MUTATED	20	4	16
ZFPM1 WILD-TYPE	21	7	11

'CLDN23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.207 (Chi-square test), Q value = 1

Table S273. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CLDN23 MUTATED	3	5	2	0	3
CLDN23 WILD-TYPE	29	18	13	10	6

'CLDN23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.361 (Chi-square test), Q value = 1

Table S274. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CLDN23 MUTATED	1	3	2	3	3
CLDN23 WILD-TYPE	17	8	19	15	8

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S275. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CLDN23 MUTATED	1	2	1	8
CLDN23 WILD-TYPE	23	12	16	15

Figure S15. Get High-res Image Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CLDN23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S276. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CLDN23 MUTATED	3	8	1
CLDN23 WILD-TYPE	20	25	21

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 1

Table S277. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CLDN23 MUTATED	3	2	7
CLDN23 WILD-TYPE	34	14	19

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S278. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CLDN23 MUTATED	4	3	5
CLDN23 WILD-TYPE	22	7	38

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 1

Table S279. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CLDN23 MUTATED	3	3	6
CLDN23 WILD-TYPE	35	15	17

'CLDN23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S280. Gene #35: 'CLDN23 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CLDN23 MUTATED	5	3	4
CLDN23 WILD-TYPE	36	8	23

'CCDC105 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0641 (Chi-square test), Q value = 1

Table S281. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC105 MUTATED	3	2	2	4	0
CCDC105 WILD-TYPE	29	21	13	6	9

'CCDC105 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00159 (Chi-square test), Q value = 1

Table S282. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC105 MUTATED	1	5	1	0	3
CCDC105 WILD-TYPE	17	6	20	18	8

Figure S16. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S283. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC105 MUTATED	4	2	2	2
CCDC105 WILD-TYPE	20	12	15	21

'CCDC105 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S284. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC105 MUTATED	6	2	2
CCDC105 WILD-TYPE	17	31	20

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S285. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC105 MUTATED	7	1	2
CCDC105 WILD-TYPE	30	15	24

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0204 (Fisher's exact test), Q value = 1

Table S286. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC105 MUTATED	0	1	9
CCDC105 WILD-TYPE	26	9	34

Figure S17. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S287. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC105 MUTATED	7	2	1
CCDC105 WILD-TYPE	31	16	22

'CCDC105 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0166 (Fisher's exact test), Q value = 1

Table S288. Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC105 MUTATED	9	1	0
CCDC105 WILD-TYPE	32	10	27

Figure S18. Get High-res Image Gene #36: 'CCDC105 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'DMKN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.688 (Chi-square test), Q value = 1

Table S289. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMKN MUTATED	1	1	0	1	0
DMKN WILD-TYPE	31	22	15	9	9

'DMKN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.333 (Chi-square test), Q value = 1

Table S290. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMKN MUTATED	0	1	2	0	0
DMKN WILD-TYPE	18	10	19	18	11

'DMKN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S291. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMKN MUTATED	1	1	1	0
DMKN WILD-TYPE	23	13	16	23

'DMKN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S292. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMKN MUTATED	1	0	2
DMKN WILD-TYPE	22	33	20

'DMKN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00708 (Fisher's exact test), Q value = 1

Table S293. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	37	13	26

Figure S19. Get High-res Image Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S294. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMKN MUTATED	1	0	2
DMKN WILD-TYPE	25	10	41

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0103 (Fisher's exact test), Q value = 1

Table S295. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMKN MUTATED	0	3	0
DMKN WILD-TYPE	38	15	23

Figure S20. Get High-res Image Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'DMKN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S296. Gene #37: 'DMKN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMKN MUTATED	2	0	1
DMKN WILD-TYPE	39	11	26

'NOL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.469 (Chi-square test), Q value = 1

Table S297. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOL9 MUTATED	5	2	1	3	1
NOL9 WILD-TYPE	27	21	14	7	8

'NOL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.647 (Chi-square test), Q value = 1

Table S298. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOL9 MUTATED	3	2	2	2	0
NOL9 WILD-TYPE	15	9	19	16	11

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S299. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOL9 MUTATED	5	0	2	2
NOL9 WILD-TYPE	19	14	15	21

'NOL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S300. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	18	31	20

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S301. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	32	14	24

'NOL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S302. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOL9 MUTATED	3	0	6
NOL9 WILD-TYPE	23	10	37

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S303. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOL9 MUTATED	5	2	2
NOL9 WILD-TYPE	33	16	21

'NOL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S304. Gene #38: 'NOL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOL9 MUTATED	6	0	3
NOL9 WILD-TYPE	35	11	24

'C19ORF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Chi-square test), Q value = 1

Table S305. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C19ORF10 MUTATED	4	2	1	2	0
C19ORF10 WILD-TYPE	28	21	14	8	9

'C19ORF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.16 (Chi-square test), Q value = 1

Table S306. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C19ORF10 MUTATED	4	1	3	0	0
C19ORF10 WILD-TYPE	14	10	18	18	11

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S307. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C19ORF10 MUTATED	3	3	2	0
C19ORF10 WILD-TYPE	21	11	15	23

'C19ORF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00708 (Fisher's exact test), Q value = 1

Table S308. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C19ORF10 MUTATED	3	0	5
C19ORF10 WILD-TYPE	20	33	17

Figure S21. Get High-res Image Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 1

Table S309. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C19ORF10 MUTATED	4	3	1
C19ORF10 WILD-TYPE	33	13	25

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S310. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C19ORF10 MUTATED	3	0	5
C19ORF10 WILD-TYPE	23	10	38

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S311. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C19ORF10 MUTATED	5	3	0
C19ORF10 WILD-TYPE	33	15	23

'C19ORF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S312. Gene #39: 'C19ORF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C19ORF10 MUTATED	5	0	3
C19ORF10 WILD-TYPE	36	11	24

'ZNF598 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Chi-square test), Q value = 1

Table S313. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF598 MUTATED	8	3	2	4	2
ZNF598 WILD-TYPE	24	20	13	6	7

'ZNF598 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.414 (Chi-square test), Q value = 1

Table S314. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF598 MUTATED	3	0	3	5	2
ZNF598 WILD-TYPE	15	11	18	13	9

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S315. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF598 MUTATED	5	1	3	4
ZNF598 WILD-TYPE	19	13	14	19

'ZNF598 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S316. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF598 MUTATED	4	6	3
ZNF598 WILD-TYPE	19	27	19

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S317. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF598 MUTATED	5	3	5
ZNF598 WILD-TYPE	32	13	21

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S318. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF598 MUTATED	5	1	7
ZNF598 WILD-TYPE	21	9	36

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S319. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF598 MUTATED	5	3	5
ZNF598 WILD-TYPE	33	15	18

'ZNF598 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S320. Gene #40: 'ZNF598 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF598 MUTATED	6	1	6
ZNF598 WILD-TYPE	35	10	21

'THEM4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00763 (Chi-square test), Q value = 1

Table S321. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
THEM4 MUTATED	4	0	3	5	2
THEM4 WILD-TYPE	28	23	12	5	7

Figure S22. Get High-res Image Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'THEM4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.251 (Chi-square test), Q value = 1

Table S322. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
THEM4 MUTATED	1	3	3	1	3
THEM4 WILD-TYPE	17	8	18	17	8

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.97 (Fisher's exact test), Q value = 1

Table S323. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
THEM4 MUTATED	3	2	3	3
THEM4 WILD-TYPE	21	12	14	20

'THEM4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S324. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
THEM4 MUTATED	4	4	3
THEM4 WILD-TYPE	19	29	19

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S325. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
THEM4 MUTATED	6	3	2
THEM4 WILD-TYPE	31	13	24

'THEM4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S326. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
THEM4 MUTATED	1	2	8
THEM4 WILD-TYPE	25	8	35

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S327. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
THEM4 MUTATED	6	3	2
THEM4 WILD-TYPE	32	15	21

'THEM4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0872 (Fisher's exact test), Q value = 1

Table S328. Gene #41: 'THEM4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
THEM4 MUTATED	7	3	1
THEM4 WILD-TYPE	34	8	26

'LRIG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.533 (Chi-square test), Q value = 1

Table S329. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRIG1 MUTATED	12	5	7	4	4
LRIG1 WILD-TYPE	20	18	8	6	5

'LRIG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.731 (Chi-square test), Q value = 1

Table S330. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRIG1 MUTATED	6	5	8	6	2
LRIG1 WILD-TYPE	12	6	13	12	9

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S331. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRIG1 MUTATED	9	6	4	7
LRIG1 WILD-TYPE	15	8	13	16

'LRIG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S332. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRIG1 MUTATED	9	11	6
LRIG1 WILD-TYPE	14	22	16

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S333. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRIG1 MUTATED	12	8	7
LRIG1 WILD-TYPE	25	8	19

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S334. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRIG1 MUTATED	8	4	15
LRIG1 WILD-TYPE	18	6	28

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S335. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRIG1 MUTATED	13	7	7
LRIG1 WILD-TYPE	25	11	16

'LRIG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S336. Gene #42: 'LRIG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRIG1 MUTATED	14	5	8
LRIG1 WILD-TYPE	27	6	19

'MUC5B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.759 (Chi-square test), Q value = 1

Table S337. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MUC5B MUTATED	7	6	4	3	4
MUC5B WILD-TYPE	25	17	11	7	5

'MUC5B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.248 (Chi-square test), Q value = 1

Table S338. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MUC5B MUTATED	3	3	7	4	6
MUC5B WILD-TYPE	15	8	14	14	5

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S339. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MUC5B MUTATED	5	4	8	6
MUC5B WILD-TYPE	19	10	9	17

'MUC5B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S340. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MUC5B MUTATED	4	11	8
MUC5B WILD-TYPE	19	22	14

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S341. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MUC5B MUTATED	9	5	9
MUC5B WILD-TYPE	28	11	17

'MUC5B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S342. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MUC5B MUTATED	8	3	12
MUC5B WILD-TYPE	18	7	31

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S343. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MUC5B MUTATED	9	7	7
MUC5B WILD-TYPE	29	11	16

'MUC5B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S344. Gene #43: 'MUC5B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MUC5B MUTATED	11	3	9
MUC5B WILD-TYPE	30	8	18

'CTGF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.632 (Chi-square test), Q value = 1

Table S345. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CTGF MUTATED	3	2	0	0	1
CTGF WILD-TYPE	29	21	15	10	8

'CTGF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.397 (Chi-square test), Q value = 1

Table S346. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CTGF MUTATED	0	1	1	1	2
CTGF WILD-TYPE	18	10	20	17	9

'CTGF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S347. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CTGF MUTATED	2	1	0	2
CTGF WILD-TYPE	22	13	17	21

'CTGF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S348. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CTGF MUTATED	1	3	1
CTGF WILD-TYPE	22	30	21

'CTGF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S349. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	36	14	24

'CTGF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S350. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	25	8	41

'CTGF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S351. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	37	16	21

'CTGF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S352. Gene #44: 'CTGF MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CTGF MUTATED	1	2	2
CTGF WILD-TYPE	40	9	25

'AMDHD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0677 (Chi-square test), Q value = 1

Table S353. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AMDHD1 MUTATED	8	2	2	5	1
AMDHD1 WILD-TYPE	24	21	13	5	8

'AMDHD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.896 (Chi-square test), Q value = 1

Table S354. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AMDHD1 MUTATED	2	2	5	3	2
AMDHD1 WILD-TYPE	16	9	16	15	9

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S355. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AMDHD1 MUTATED	5	3	4	2
AMDHD1 WILD-TYPE	19	11	13	21

'AMDHD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S356. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AMDHD1 MUTATED	3	6	5
AMDHD1 WILD-TYPE	20	27	17

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 1

Table S357. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AMDHD1 MUTATED	6	5	3
AMDHD1 WILD-TYPE	31	11	23

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 1

Table S358. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AMDHD1 MUTATED	6	0	8
AMDHD1 WILD-TYPE	20	10	35

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0186 (Fisher's exact test), Q value = 1

Table S359. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AMDHD1 MUTATED	6	7	1
AMDHD1 WILD-TYPE	32	11	22

Figure S23. Get High-res Image Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'AMDHD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S360. Gene #45: 'AMDHD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AMDHD1 MUTATED	6	1	7
AMDHD1 WILD-TYPE	35	10	20

'RNF149 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Chi-square test), Q value = 1

Table S361. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF149 MUTATED	2	3	1	1	0
RNF149 WILD-TYPE	30	20	14	9	9

'RNF149 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.56 (Chi-square test), Q value = 1

Table S362. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF149 MUTATED	1	0	2	1	2
RNF149 WILD-TYPE	17	11	19	17	9

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S363. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF149 MUTATED	1	1	2	2
RNF149 WILD-TYPE	23	13	15	21

'RNF149 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S364. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	22	30	20

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0871 (Fisher's exact test), Q value = 1

Table S365. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	36	13	24

'RNF149 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S366. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF149 MUTATED	4	1	1
RNF149 WILD-TYPE	22	9	42

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S367. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF149 MUTATED	1	3	2
RNF149 WILD-TYPE	37	15	21

'RNF149 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S368. Gene #46: 'RNF149 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF149 MUTATED	1	1	4
RNF149 WILD-TYPE	40	10	23

'MSH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00899 (Chi-square test), Q value = 1

Table S369. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MSH3 MUTATED	1	0	1	3	0
MSH3 WILD-TYPE	31	23	14	7	9

Figure S24. Get High-res Image Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'MSH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S370. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MSH3 MUTATED	1	0	2	0	1
MSH3 WILD-TYPE	17	11	19	18	10

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0701 (Fisher's exact test), Q value = 1

Table S371. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MSH3 MUTATED	1	0	3	0
MSH3 WILD-TYPE	23	14	14	23

'MSH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S372. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MSH3 MUTATED	1	1	2
MSH3 WILD-TYPE	22	32	20

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S373. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	33	16	26

'MSH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S374. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MSH3 MUTATED	0	0	4
MSH3 WILD-TYPE	26	10	39

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S375. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	34	18	23

'MSH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S376. Gene #47: 'MSH3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MSH3 MUTATED	4	0	0
MSH3 WILD-TYPE	37	11	27

'ALPPL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.907 (Chi-square test), Q value = 1

Table S377. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ALPPL2 MUTATED	3	1	2	1	1
ALPPL2 WILD-TYPE	29	22	13	9	8

'ALPPL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.121 (Chi-square test), Q value = 1

Table S378. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ALPPL2 MUTATED	4	0	0	2	2
ALPPL2 WILD-TYPE	14	11	21	16	9

'ALPPL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S379. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ALPPL2 MUTATED	4	1	0	3
ALPPL2 WILD-TYPE	20	13	17	20

'ALPPL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.365 (Fisher's exact test), Q value = 1

Table S380. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ALPPL2 MUTATED	4	3	1
ALPPL2 WILD-TYPE	19	30	21

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S381. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ALPPL2 MUTATED	5	1	2
ALPPL2 WILD-TYPE	32	15	24

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S382. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ALPPL2 MUTATED	1	2	5
ALPPL2 WILD-TYPE	25	8	38

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S383. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ALPPL2 MUTATED	5	1	2
ALPPL2 WILD-TYPE	33	17	21

'ALPPL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S384. Gene #48: 'ALPPL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ALPPL2 MUTATED	5	2	1
ALPPL2 WILD-TYPE	36	9	26

'SNED1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Chi-square test), Q value = 1

Table S385. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SNED1 MUTATED	4	1	1	0	1
SNED1 WILD-TYPE	28	22	14	10	8

'SNED1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.623 (Chi-square test), Q value = 1

Table S386. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SNED1 MUTATED	2	2	2	1	0
SNED1 WILD-TYPE	16	9	19	17	11

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S387. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SNED1 MUTATED	4	1	1	1
SNED1 WILD-TYPE	20	13	16	22

'SNED1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S388. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SNED1 MUTATED	3	2	2
SNED1 WILD-TYPE	20	31	20

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0417 (Fisher's exact test), Q value = 1

Table S389. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SNED1 MUTATED	2	4	1
SNED1 WILD-TYPE	35	12	25

Figure S25. Get High-res Image Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'SNED1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S390. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SNED1 MUTATED	3	1	3
SNED1 WILD-TYPE	23	9	40

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S391. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SNED1 MUTATED	2	4	1
SNED1 WILD-TYPE	36	14	22

'SNED1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S392. Gene #49: 'SNED1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SNED1 MUTATED	3	1	3
SNED1 WILD-TYPE	38	10	24

'NOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.284 (Chi-square test), Q value = 1

Table S393. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOXA1 MUTATED	3	0	2	0	0
NOXA1 WILD-TYPE	29	23	13	10	9

'NOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.371 (Chi-square test), Q value = 1

Table S394. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOXA1 MUTATED	2	0	1	0	0
NOXA1 WILD-TYPE	16	11	20	18	11

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 1

Table S395. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOXA1 MUTATED	2	1	0	0
NOXA1 WILD-TYPE	22	13	17	23

'NOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S396. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOXA1 MUTATED	2	0	1
NOXA1 WILD-TYPE	21	33	21

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S397. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	34	16	26

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S398. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOXA1 MUTATED	0	0	3
NOXA1 WILD-TYPE	26	10	40

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S399. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	35	18	23

'NOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S400. Gene #50: 'NOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOXA1 MUTATED	3	0	0
NOXA1 WILD-TYPE	38	11	27

'OPRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.24 (Chi-square test), Q value = 1

Table S401. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
OPRD1 MUTATED	12	6	4	4	0
OPRD1 WILD-TYPE	20	17	11	6	9

'OPRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.832 (Chi-square test), Q value = 1

Table S402. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
OPRD1 MUTATED	6	2	6	4	4
OPRD1 WILD-TYPE	12	9	15	14	7

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S403. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
OPRD1 MUTATED	8	5	3	6
OPRD1 WILD-TYPE	16	9	14	17

'OPRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S404. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
OPRD1 MUTATED	7	8	7
OPRD1 WILD-TYPE	16	25	15

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S405. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
OPRD1 MUTATED	12	5	5
OPRD1 WILD-TYPE	25	11	21

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S406. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
OPRD1 MUTATED	8	1	13
OPRD1 WILD-TYPE	18	9	30

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S407. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
OPRD1 MUTATED	12	5	5
OPRD1 WILD-TYPE	26	13	18

'OPRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S408. Gene #51: 'OPRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
OPRD1 MUTATED	11	2	9
OPRD1 WILD-TYPE	30	9	18

'CCDC102A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.587 (Chi-square test), Q value = 1

Table S409. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC102A MUTATED	9	8	2	4	3
CCDC102A WILD-TYPE	23	15	13	6	6

'CCDC102A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S410. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC102A MUTATED	4	3	8	5	3
CCDC102A WILD-TYPE	14	8	13	13	8

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S411. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC102A MUTATED	6	5	5	7
CCDC102A WILD-TYPE	18	9	12	16

'CCDC102A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S412. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC102A MUTATED	6	11	6
CCDC102A WILD-TYPE	17	22	16

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S413. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC102A MUTATED	11	3	9
CCDC102A WILD-TYPE	26	13	17

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S414. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC102A MUTATED	8	4	11
CCDC102A WILD-TYPE	18	6	32

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S415. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC102A MUTATED	11	4	8
CCDC102A WILD-TYPE	27	14	15

'CCDC102A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.385 (Fisher's exact test), Q value = 1

Table S416. Gene #52: 'CCDC102A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC102A MUTATED	10	5	8
CCDC102A WILD-TYPE	31	6	19

'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.11 (Chi-square test), Q value = 1

Table S417. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KCTD3 MUTATED	2	1	2	3	0
KCTD3 WILD-TYPE	30	22	13	7	9

'KCTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0699 (Chi-square test), Q value = 1

Table S418. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KCTD3 MUTATED	0	0	2	1	3
KCTD3 WILD-TYPE	18	11	19	17	8

'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S419. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KCTD3 MUTATED	1	2	1	2
KCTD3 WILD-TYPE	23	12	16	21

'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S420. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KCTD3 MUTATED	1	2	3
KCTD3 WILD-TYPE	22	31	19

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S421. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KCTD3 MUTATED	3	1	2
KCTD3 WILD-TYPE	34	15	24

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S422. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KCTD3 MUTATED	1	1	4
KCTD3 WILD-TYPE	25	9	39

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S423. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KCTD3 MUTATED	3	1	2
KCTD3 WILD-TYPE	35	17	21

'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S424. Gene #53: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KCTD3 MUTATED	4	1	1
KCTD3 WILD-TYPE	37	10	26

'C1ORF106 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.9 (Chi-square test), Q value = 1

Table S425. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C1ORF106 MUTATED	7	3	3	2	1
C1ORF106 WILD-TYPE	25	20	12	8	8

'C1ORF106 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.439 (Chi-square test), Q value = 1

Table S426. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C1ORF106 MUTATED	3	1	4	2	4
C1ORF106 WILD-TYPE	15	10	17	16	7

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S427. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C1ORF106 MUTATED	6	3	3	2
C1ORF106 WILD-TYPE	18	11	14	21

'C1ORF106 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S428. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C1ORF106 MUTATED	5	6	3
C1ORF106 WILD-TYPE	18	27	19

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S429. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C1ORF106 MUTATED	7	3	4
C1ORF106 WILD-TYPE	30	13	22

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S430. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C1ORF106 MUTATED	4	3	7
C1ORF106 WILD-TYPE	22	7	36

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S431. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C1ORF106 MUTATED	7	4	3
C1ORF106 WILD-TYPE	31	14	20

'C1ORF106 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S432. Gene #54: 'C1ORF106 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C1ORF106 MUTATED	7	3	4
C1ORF106 WILD-TYPE	34	8	23

'KCNK17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.135 (Chi-square test), Q value = 1

Table S433. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KCNK17 MUTATED	4	3	5	3	4
KCNK17 WILD-TYPE	28	20	10	7	5

'KCNK17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0959 (Chi-square test), Q value = 1

Table S434. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KCNK17 MUTATED	3	3	9	2	1
KCNK17 WILD-TYPE	15	8	12	16	10

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S435. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KCNK17 MUTATED	3	5	6	4
KCNK17 WILD-TYPE	21	9	11	19

'KCNK17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0117 (Fisher's exact test), Q value = 1

Table S436. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KCNK17 MUTATED	2	6	10
KCNK17 WILD-TYPE	21	27	12

Figure S26. Get High-res Image Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S437. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KCNK17 MUTATED	8	4	6
KCNK17 WILD-TYPE	29	12	20

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S438. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KCNK17 MUTATED	4	4	10
KCNK17 WILD-TYPE	22	6	33

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S439. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KCNK17 MUTATED	8	5	5
KCNK17 WILD-TYPE	30	13	18

'KCNK17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S440. Gene #55: 'KCNK17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KCNK17 MUTATED	9	4	5
KCNK17 WILD-TYPE	32	7	22

'LACTB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0645 (Chi-square test), Q value = 1

Table S441. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LACTB MUTATED	8	6	3	7	3
LACTB WILD-TYPE	24	17	12	3	6

'LACTB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Chi-square test), Q value = 1

Table S442. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LACTB MUTATED	3	5	5	5	5
LACTB WILD-TYPE	15	6	16	13	6

'LACTB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S443. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LACTB MUTATED	8	3	5	7
LACTB WILD-TYPE	16	11	12	16

'LACTB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S444. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LACTB MUTATED	7	10	6
LACTB WILD-TYPE	16	23	16

'LACTB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S445. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LACTB MUTATED	9	6	8
LACTB WILD-TYPE	28	10	18

'LACTB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S446. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LACTB MUTATED	7	4	12
LACTB WILD-TYPE	19	6	31

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S447. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LACTB MUTATED	9	7	7
LACTB WILD-TYPE	29	11	16

'LACTB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S448. Gene #56: 'LACTB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LACTB MUTATED	11	4	8
LACTB WILD-TYPE	30	7	19

'TRIOBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.713 (Chi-square test), Q value = 1

Table S449. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TRIOBP MUTATED	10	5	5	3	1
TRIOBP WILD-TYPE	22	18	10	7	8

'TRIOBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S450. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TRIOBP MUTATED	6	2	4	4	4
TRIOBP WILD-TYPE	12	9	17	14	7

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S451. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TRIOBP MUTATED	7	4	4	4
TRIOBP WILD-TYPE	17	10	13	19

'TRIOBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S452. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TRIOBP MUTATED	7	9	3
TRIOBP WILD-TYPE	16	24	19

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S453. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TRIOBP MUTATED	9	4	7
TRIOBP WILD-TYPE	28	12	19

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S454. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TRIOBP MUTATED	7	3	10
TRIOBP WILD-TYPE	19	7	33

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S455. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TRIOBP MUTATED	9	5	6
TRIOBP WILD-TYPE	29	13	17

'TRIOBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #57: 'TRIOBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TRIOBP MUTATED	10	3	7
TRIOBP WILD-TYPE	31	8	20

'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0196 (Chi-square test), Q value = 1

Table S457. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SARM1 MUTATED	8	1	0	4	1
SARM1 WILD-TYPE	24	22	15	6	8

Figure S27. Get High-res Image Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SARM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.471 (Chi-square test), Q value = 1

Table S458. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SARM1 MUTATED	0	2	3	3	1
SARM1 WILD-TYPE	18	9	18	15	10

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S459. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SARM1 MUTATED	3	1	3	2
SARM1 WILD-TYPE	21	13	14	21

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S460. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SARM1 MUTATED	2	4	3
SARM1 WILD-TYPE	21	29	19

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S461. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SARM1 MUTATED	3	3	3
SARM1 WILD-TYPE	34	13	23

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S462. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SARM1 MUTATED	3	2	4
SARM1 WILD-TYPE	23	8	39

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S463. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SARM1 MUTATED	3	4	2
SARM1 WILD-TYPE	35	14	21

'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0591 (Fisher's exact test), Q value = 1

Table S464. Gene #58: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SARM1 MUTATED	2	3	4
SARM1 WILD-TYPE	39	8	23

'ERCC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0188 (Chi-square test), Q value = 1

Table S465. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ERCC2 MUTATED	5	3	7	4	0
ERCC2 WILD-TYPE	27	20	8	6	9

Figure S28. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ERCC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.229 (Chi-square test), Q value = 1

Table S466. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ERCC2 MUTATED	5	4	7	1	2
ERCC2 WILD-TYPE	13	7	14	17	9

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S467. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ERCC2 MUTATED	7	6	4	2
ERCC2 WILD-TYPE	17	8	13	21

'ERCC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00307 (Fisher's exact test), Q value = 1

Table S468. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ERCC2 MUTATED	8	2	9
ERCC2 WILD-TYPE	15	31	13

Figure S29. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S469. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ERCC2 MUTATED	12	4	3
ERCC2 WILD-TYPE	25	12	23

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0678 (Fisher's exact test), Q value = 1

Table S470. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ERCC2 MUTATED	5	0	14
ERCC2 WILD-TYPE	21	10	29

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.077 (Fisher's exact test), Q value = 1

Table S471. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ERCC2 MUTATED	13	4	2
ERCC2 WILD-TYPE	25	14	21

'ERCC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0388 (Fisher's exact test), Q value = 1

Table S472. Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ERCC2 MUTATED	14	0	5
ERCC2 WILD-TYPE	27	11	22

Figure S30. Get High-res Image Gene #59: 'ERCC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Chi-square test), Q value = 1

Table S473. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NEFH MUTATED	6	1	3	0	0
NEFH WILD-TYPE	26	22	12	10	9

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.382 (Chi-square test), Q value = 1

Table S474. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NEFH MUTATED	3	0	2	3	0
NEFH WILD-TYPE	15	11	19	15	11

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S475. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NEFH MUTATED	4	2	0	1
NEFH WILD-TYPE	20	12	17	22

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S476. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NEFH MUTATED	2	3	2
NEFH WILD-TYPE	21	30	20

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S477. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NEFH MUTATED	5	2	1
NEFH WILD-TYPE	32	14	25

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S478. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NEFH MUTATED	2	0	6
NEFH WILD-TYPE	24	10	37

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S479. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NEFH MUTATED	5	2	1
NEFH WILD-TYPE	33	16	22

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S480. Gene #60: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NEFH MUTATED	5	0	3
NEFH WILD-TYPE	36	11	24

'KBTBD13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.344 (Chi-square test), Q value = 1

Table S481. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KBTBD13 MUTATED	6	6	1	2	0
KBTBD13 WILD-TYPE	26	17	14	8	9

'KBTBD13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.467 (Chi-square test), Q value = 1

Table S482. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KBTBD13 MUTATED	3	2	2	4	4
KBTBD13 WILD-TYPE	15	9	19	14	7

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S483. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KBTBD13 MUTATED	6	2	2	5
KBTBD13 WILD-TYPE	18	12	15	18

'KBTBD13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.101 (Fisher's exact test), Q value = 1

Table S484. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KBTBD13 MUTATED	6	8	1
KBTBD13 WILD-TYPE	17	25	21

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S485. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	30	14	20

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S486. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KBTBD13 MUTATED	6	2	7
KBTBD13 WILD-TYPE	20	8	36

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S487. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	31	16	17

'KBTBD13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S488. Gene #61: 'KBTBD13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KBTBD13 MUTATED	7	2	6
KBTBD13 WILD-TYPE	34	9	21

'IRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.315 (Chi-square test), Q value = 1

Table S489. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IRX3 MUTATED	10	2	5	2	2
IRX3 WILD-TYPE	22	21	10	8	7

'IRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.538 (Chi-square test), Q value = 1

Table S490. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IRX3 MUTATED	2	3	5	3	4
IRX3 WILD-TYPE	16	8	16	15	7

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 1

Table S491. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IRX3 MUTATED	7	5	2	3
IRX3 WILD-TYPE	17	9	15	20

'IRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S492. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IRX3 MUTATED	6	5	6
IRX3 WILD-TYPE	17	28	16

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S493. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IRX3 MUTATED	9	5	3
IRX3 WILD-TYPE	28	11	23

'IRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S494. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IRX3 MUTATED	6	1	10
IRX3 WILD-TYPE	20	9	33

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S495. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IRX3 MUTATED	9	6	2
IRX3 WILD-TYPE	29	12	21

'IRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S496. Gene #62: 'IRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IRX3 MUTATED	9	2	6
IRX3 WILD-TYPE	32	9	21

'MUC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.829 (Chi-square test), Q value = 1

Table S497. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MUC2 MUTATED	5	4	3	2	3
MUC2 WILD-TYPE	27	19	12	8	6

'MUC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0845 (Chi-square test), Q value = 1

Table S498. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MUC2 MUTATED	0	2	7	4	1
MUC2 WILD-TYPE	18	9	14	14	10

'MUC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.098 (Fisher's exact test), Q value = 1

Table S499. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MUC2 MUTATED	1	4	5	4
MUC2 WILD-TYPE	23	10	12	19

'MUC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0889 (Fisher's exact test), Q value = 1

Table S500. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MUC2 MUTATED	1	7	6
MUC2 WILD-TYPE	22	26	16

'MUC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S501. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MUC2 MUTATED	4	5	5
MUC2 WILD-TYPE	33	11	21

'MUC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0271 (Fisher's exact test), Q value = 1

Table S502. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MUC2 MUTATED	9	1	4
MUC2 WILD-TYPE	17	9	39

Figure S31. Get High-res Image Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'MUC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S503. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MUC2 MUTATED	4	6	4
MUC2 WILD-TYPE	34	12	19

'MUC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 1

Table S504. Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MUC2 MUTATED	4	1	9
MUC2 WILD-TYPE	37	10	18

Figure S32. Get High-res Image Gene #63: 'MUC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.284 (Chi-square test), Q value = 1

Table S505. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GARS MUTATED	12	6	6	5	6
GARS WILD-TYPE	20	17	9	5	3

'GARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.562 (Chi-square test), Q value = 1

Table S506. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GARS MUTATED	5	2	9	7	5
GARS WILD-TYPE	13	9	12	11	6

'GARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S507. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GARS MUTATED	8	3	7	10
GARS WILD-TYPE	16	11	10	13

'GARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S508. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GARS MUTATED	6	16	6
GARS WILD-TYPE	17	17	16

'GARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S509. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GARS MUTATED	10	5	13
GARS WILD-TYPE	27	11	13

'GARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0436 (Fisher's exact test), Q value = 1

Table S510. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GARS MUTATED	13	5	10
GARS WILD-TYPE	13	5	33

Figure S33. Get High-res Image Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S511. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GARS MUTATED	10	6	12
GARS WILD-TYPE	28	12	11

'GARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0908 (Fisher's exact test), Q value = 1

Table S512. Gene #64: 'GARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GARS MUTATED	10	5	13
GARS WILD-TYPE	31	6	14

'UQCRFS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.885 (Chi-square test), Q value = 1

Table S513. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
UQCRFS1 MUTATED	4	2	3	1	1
UQCRFS1 WILD-TYPE	28	21	12	9	8

'UQCRFS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.429 (Chi-square test), Q value = 1

Table S514. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
UQCRFS1 MUTATED	4	1	5	1	1
UQCRFS1 WILD-TYPE	14	10	16	17	10

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S515. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
UQCRFS1 MUTATED	4	2	3	2
UQCRFS1 WILD-TYPE	20	12	14	21

'UQCRFS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S516. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
UQCRFS1 MUTATED	4	3	4
UQCRFS1 WILD-TYPE	19	30	18

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S517. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
UQCRFS1 MUTATED	8	1	3
UQCRFS1 WILD-TYPE	29	15	23

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0717 (Fisher's exact test), Q value = 1

Table S518. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
UQCRFS1 MUTATED	1	3	8
UQCRFS1 WILD-TYPE	25	7	35

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S519. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
UQCRFS1 MUTATED	8	1	3
UQCRFS1 WILD-TYPE	30	17	20

'UQCRFS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0653 (Fisher's exact test), Q value = 1

Table S520. Gene #65: 'UQCRFS1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
UQCRFS1 MUTATED	8	3	1
UQCRFS1 WILD-TYPE	33	8	26

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S521. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATXN1 MUTATED	5	4	3	0	2
ATXN1 WILD-TYPE	27	19	12	10	7

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.178 (Chi-square test), Q value = 1

Table S522. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATXN1 MUTATED	1	4	2	2	2
ATXN1 WILD-TYPE	17	7	19	16	9

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S523. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATXN1 MUTATED	2	3	3	3
ATXN1 WILD-TYPE	22	11	14	20

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S524. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATXN1 MUTATED	3	4	4
ATXN1 WILD-TYPE	20	29	18

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S525. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATXN1 MUTATED	5	3	3
ATXN1 WILD-TYPE	32	13	23

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S526. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATXN1 MUTATED	3	1	7
ATXN1 WILD-TYPE	23	9	36

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S527. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATXN1 MUTATED	5	3	3
ATXN1 WILD-TYPE	33	15	20

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S528. Gene #66: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATXN1 MUTATED	7	1	3
ATXN1 WILD-TYPE	34	10	24

'ZNF628 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0739 (Chi-square test), Q value = 1

Table S529. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF628 MUTATED	7	1	0	2	0
ZNF628 WILD-TYPE	25	22	15	8	9

'ZNF628 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Chi-square test), Q value = 1

Table S530. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZNF628 MUTATED	3	2	1	1	0
ZNF628 WILD-TYPE	15	9	20	17	11

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0703 (Fisher's exact test), Q value = 1

Table S531. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZNF628 MUTATED	5	1	1	0
ZNF628 WILD-TYPE	19	13	16	23

'ZNF628 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.059 (Fisher's exact test), Q value = 1

Table S532. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZNF628 MUTATED	5	1	1
ZNF628 WILD-TYPE	18	32	21

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0417 (Fisher's exact test), Q value = 1

Table S533. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZNF628 MUTATED	2	4	1
ZNF628 WILD-TYPE	35	12	25

Figure S34. Get High-res Image Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S534. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZNF628 MUTATED	4	0	3
ZNF628 WILD-TYPE	22	10	40

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0433 (Fisher's exact test), Q value = 1

Table S535. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZNF628 MUTATED	3	4	0
ZNF628 WILD-TYPE	35	14	23

Figure S35. Get High-res Image Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'ZNF628 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S536. Gene #67: 'ZNF628 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZNF628 MUTATED	3	0	4
ZNF628 WILD-TYPE	38	11	23

'DSPP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S537. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DSPP MUTATED	5	4	3	1	0
DSPP WILD-TYPE	27	19	12	9	9

'DSPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.175 (Chi-square test), Q value = 1

Table S538. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DSPP MUTATED	1	4	2	3	1
DSPP WILD-TYPE	17	7	19	15	10

'DSPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S539. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DSPP MUTATED	3	3	2	3
DSPP WILD-TYPE	21	11	15	20

'DSPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.917 (Fisher's exact test), Q value = 1

Table S540. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DSPP MUTATED	4	4	3
DSPP WILD-TYPE	19	29	19

'DSPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.833 (Fisher's exact test), Q value = 1

Table S541. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DSPP MUTATED	5	3	3
DSPP WILD-TYPE	32	13	23

'DSPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S542. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DSPP MUTATED	4	0	7
DSPP WILD-TYPE	22	10	36

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S543. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DSPP MUTATED	5	4	2
DSPP WILD-TYPE	33	14	21

'DSPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S544. Gene #68: 'DSPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DSPP MUTATED	7	0	4
DSPP WILD-TYPE	34	11	23

'ASPDH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.289 (Chi-square test), Q value = 1

Table S545. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ASPDH MUTATED	7	4	4	4	0
ASPDH WILD-TYPE	25	19	11	6	9

'ASPDH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.674 (Chi-square test), Q value = 1

Table S546. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ASPDH MUTATED	3	3	6	2	2
ASPDH WILD-TYPE	15	8	15	16	9

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0774 (Fisher's exact test), Q value = 1

Table S547. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ASPDH MUTATED	6	3	6	1
ASPDH WILD-TYPE	18	11	11	22

'ASPDH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0874 (Fisher's exact test), Q value = 1

Table S548. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ASPDH MUTATED	6	3	7
ASPDH WILD-TYPE	17	30	15

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S549. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ASPDH MUTATED	11	2	3
ASPDH WILD-TYPE	26	14	23

'ASPDH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00171 (Fisher's exact test), Q value = 1

Table S550. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ASPDH MUTATED	0	3	13
ASPDH WILD-TYPE	26	7	30

Figure S36. Get High-res Image Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0539 (Fisher's exact test), Q value = 1

Table S551. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ASPDH MUTATED	12	1	3
ASPDH WILD-TYPE	26	17	20

'ASPDH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00136 (Fisher's exact test), Q value = 1

Table S552. Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ASPDH MUTATED	13	3	0
ASPDH WILD-TYPE	28	8	27

Figure S37. Get High-res Image Gene #69: 'ASPDH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.312 (Chi-square test), Q value = 1

Table S553. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CSGALNACT2 MUTATED	1	3	0	0	1
CSGALNACT2 WILD-TYPE	31	20	15	10	8

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0371 (Chi-square test), Q value = 1

Table S554. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CSGALNACT2 MUTATED	1	0	1	0	3
CSGALNACT2 WILD-TYPE	17	11	20	18	8

Figure S38. Get High-res Image Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S555. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CSGALNACT2 MUTATED	1	0	2	2
CSGALNACT2 WILD-TYPE	23	14	15	21

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S556. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CSGALNACT2 MUTATED	1	4	0
CSGALNACT2 WILD-TYPE	22	29	22

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 1

Table S557. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CSGALNACT2 MUTATED	1	0	4
CSGALNACT2 WILD-TYPE	36	16	22

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 1

Table S558. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CSGALNACT2 MUTATED	3	1	1
CSGALNACT2 WILD-TYPE	23	9	42

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S559. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CSGALNACT2 MUTATED	1	1	3
CSGALNACT2 WILD-TYPE	37	17	20

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S560. Gene #70: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CSGALNACT2 MUTATED	1	1	3
CSGALNACT2 WILD-TYPE	40	10	24

'TPO MUTATION STATUS' versus 'CN_CNMF'

P value = 0.297 (Chi-square test), Q value = 1

Table S561. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TPO MUTATED	11	3	2	2	3
TPO WILD-TYPE	21	20	13	8	6

'TPO MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.102 (Chi-square test), Q value = 1

Table S562. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TPO MUTATED	5	5	1	5	2
TPO WILD-TYPE	13	6	20	13	9

'TPO MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 1

Table S563. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TPO MUTATED	9	3	2	4
TPO WILD-TYPE	15	11	15	19

'TPO MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S564. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TPO MUTATED	8	7	3
TPO WILD-TYPE	15	26	19

'TPO MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S565. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TPO MUTATED	8	6	4
TPO WILD-TYPE	29	10	22

'TPO MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S566. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TPO MUTATED	6	2	10
TPO WILD-TYPE	20	8	33

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S567. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TPO MUTATED	8	7	3
TPO WILD-TYPE	30	11	20

'TPO MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S568. Gene #71: 'TPO MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TPO MUTATED	8	3	7
TPO WILD-TYPE	33	8	20

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.262 (Chi-square test), Q value = 1

Table S569. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP4-5 MUTATED	2	4	0	0	1
KRTAP4-5 WILD-TYPE	30	19	15	10	8

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.115 (Chi-square test), Q value = 1

Table S570. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP4-5 MUTATED	1	3	1	1	0
KRTAP4-5 WILD-TYPE	17	8	20	17	11

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.722 (Fisher's exact test), Q value = 1

Table S571. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP4-5 MUTATED	2	0	2	2
KRTAP4-5 WILD-TYPE	22	14	15	21

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S572. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP4-5 MUTATED	2	3	1
KRTAP4-5 WILD-TYPE	21	30	21

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S573. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP4-5 MUTATED	2	1	3
KRTAP4-5 WILD-TYPE	35	15	23

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S574. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP4-5 MUTATED	1	2	3
KRTAP4-5 WILD-TYPE	25	8	40

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S575. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP4-5 MUTATED	2	1	3
KRTAP4-5 WILD-TYPE	36	17	20

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S576. Gene #72: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP4-5 MUTATED	3	2	1
KRTAP4-5 WILD-TYPE	38	9	26

'GLTSCR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.504 (Chi-square test), Q value = 1

Table S577. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLTSCR2 MUTATED	5	1	1	1	0
GLTSCR2 WILD-TYPE	27	22	14	9	9

'GLTSCR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.173 (Chi-square test), Q value = 1

Table S578. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLTSCR2 MUTATED	4	0	2	1	0
GLTSCR2 WILD-TYPE	14	11	19	17	11

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S579. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLTSCR2 MUTATED	4	1	2	0
GLTSCR2 WILD-TYPE	20	13	15	23

'GLTSCR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S580. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLTSCR2 MUTATED	3	2	2
GLTSCR2 WILD-TYPE	20	31	20

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 1

Table S581. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLTSCR2 MUTATED	2	3	2
GLTSCR2 WILD-TYPE	35	13	24

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S582. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLTSCR2 MUTATED	4	1	2
GLTSCR2 WILD-TYPE	22	9	41

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S583. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLTSCR2 MUTATED	2	4	1
GLTSCR2 WILD-TYPE	36	14	22

'GLTSCR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S584. Gene #73: 'GLTSCR2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLTSCR2 MUTATED	2	1	4
GLTSCR2 WILD-TYPE	39	10	23

'PANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S585. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PANK2 MUTATED	7	2	2	2	2
PANK2 WILD-TYPE	25	21	13	8	7

'PANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.802 (Chi-square test), Q value = 1

Table S586. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PANK2 MUTATED	3	1	2	4	2
PANK2 WILD-TYPE	15	10	19	14	9

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S587. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PANK2 MUTATED	5	1	2	4
PANK2 WILD-TYPE	19	13	15	19

'PANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S588. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PANK2 MUTATED	4	6	2
PANK2 WILD-TYPE	19	27	20

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PANK2 MUTATED	6	2	4
PANK2 WILD-TYPE	31	14	22

'PANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S590. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PANK2 MUTATED	3	2	7
PANK2 WILD-TYPE	23	8	36

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S591. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PANK2 MUTATED	6	3	3
PANK2 WILD-TYPE	32	15	20

'PANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S592. Gene #74: 'PANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PANK2 MUTATED	5	3	4
PANK2 WILD-TYPE	36	8	23

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.416 (Chi-square test), Q value = 1

Table S593. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF39 MUTATED	2	1	2	2	0
RNF39 WILD-TYPE	30	22	13	8	9

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Chi-square test), Q value = 1

Table S594. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF39 MUTATED	1	2	4	0	0
RNF39 WILD-TYPE	17	9	17	18	11

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0334 (Fisher's exact test), Q value = 1

Table S595. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF39 MUTATED	1	2	4	0
RNF39 WILD-TYPE	23	12	13	23

Figure S39. Get High-res Image Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00798 (Fisher's exact test), Q value = 1

Table S596. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF39 MUTATED	2	0	5
RNF39 WILD-TYPE	21	33	17

Figure S40. Get High-res Image Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0544 (Fisher's exact test), Q value = 1

Table S597. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF39 MUTATED	4	3	0
RNF39 WILD-TYPE	33	13	26

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S598. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF39 MUTATED	2	0	5
RNF39 WILD-TYPE	24	10	38

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S599. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF39 MUTATED	4	3	0
RNF39 WILD-TYPE	34	15	23

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S600. Gene #75: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF39 MUTATED	5	0	2
RNF39 WILD-TYPE	36	11	25

'MAL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.275 (Chi-square test), Q value = 1

Table S601. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MAL2 MUTATED	7	8	6	1	1
MAL2 WILD-TYPE	25	15	9	9	8

'MAL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.782 (Chi-square test), Q value = 1

Table S602. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MAL2 MUTATED	3	3	3	5	3
MAL2 WILD-TYPE	15	8	18	13	8

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0202 (Fisher's exact test), Q value = 1

Table S603. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MAL2 MUTATED	5	6	0	6
MAL2 WILD-TYPE	19	8	17	17

Figure S41. Get High-res Image Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MAL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S604. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MAL2 MUTATED	5	7	5
MAL2 WILD-TYPE	18	26	17

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S605. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MAL2 MUTATED	6	5	6
MAL2 WILD-TYPE	31	11	20

'MAL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S606. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MAL2 MUTATED	7	2	8
MAL2 WILD-TYPE	19	8	35

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S607. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MAL2 MUTATED	7	4	6
MAL2 WILD-TYPE	31	14	17

'MAL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S608. Gene #76: 'MAL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MAL2 MUTATED	8	2	7
MAL2 WILD-TYPE	33	9	20

'ZAR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.252 (Chi-square test), Q value = 1

Table S609. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZAR1 MUTATED	6	5	1	3	4
ZAR1 WILD-TYPE	26	18	14	7	5

'ZAR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.634 (Chi-square test), Q value = 1

Table S610. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZAR1 MUTATED	3	3	3	4	4
ZAR1 WILD-TYPE	15	8	18	14	7

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S611. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZAR1 MUTATED	6	1	4	6
ZAR1 WILD-TYPE	18	13	13	17

'ZAR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S612. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZAR1 MUTATED	6	8	3
ZAR1 WILD-TYPE	17	25	19

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S613. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZAR1 MUTATED	9	1	7
ZAR1 WILD-TYPE	28	15	19

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S614. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZAR1 MUTATED	6	2	9
ZAR1 WILD-TYPE	20	8	34

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S615. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZAR1 MUTATED	9	2	6
ZAR1 WILD-TYPE	29	16	17

'ZAR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S616. Gene #77: 'ZAR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZAR1 MUTATED	8	3	6
ZAR1 WILD-TYPE	33	8	21

'C16ORF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.734 (Chi-square test), Q value = 1

Table S617. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C16ORF3 MUTATED	3	3	0	1	1
C16ORF3 WILD-TYPE	29	20	15	9	8

'C16ORF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00275 (Chi-square test), Q value = 1

Table S618. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C16ORF3 MUTATED	0	4	1	0	1
C16ORF3 WILD-TYPE	18	7	20	18	10

Figure S42. Get High-res Image Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S619. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C16ORF3 MUTATED	1	1	3	1
C16ORF3 WILD-TYPE	23	13	14	22

'C16ORF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S620. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	21	31	20

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S621. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	35	14	24

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S622. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C16ORF3 MUTATED	2	1	3
C16ORF3 WILD-TYPE	24	9	40

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S623. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C16ORF3 MUTATED	2	2	2
C16ORF3 WILD-TYPE	36	16	21

'C16ORF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S624. Gene #78: 'C16ORF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C16ORF3 MUTATED	3	1	2
C16ORF3 WILD-TYPE	38	10	25

'KRTAP5-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S625. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP5-5 MUTATED	3	1	1	2	0
KRTAP5-5 WILD-TYPE	29	22	14	8	9

'KRTAP5-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S626. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP5-5 MUTATED	2	0	1	2	0
KRTAP5-5 WILD-TYPE	16	11	20	16	11

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S627. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP5-5 MUTATED	3	1	0	1
KRTAP5-5 WILD-TYPE	21	13	17	22

'KRTAP5-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S628. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	21	31	21

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S629. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	35	14	25

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S630. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP5-5 MUTATED	2	1	2
KRTAP5-5 WILD-TYPE	24	9	41

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S631. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP5-5 MUTATED	2	2	1
KRTAP5-5 WILD-TYPE	36	16	22

'KRTAP5-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S632. Gene #79: 'KRTAP5-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP5-5 MUTATED	2	1	2
KRTAP5-5 WILD-TYPE	39	10	25

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.378 (Chi-square test), Q value = 1

Table S633. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CRIPAK MUTATED	4	5	2	4	2
CRIPAK WILD-TYPE	28	18	13	6	7

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.566 (Chi-square test), Q value = 1

Table S634. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CRIPAK MUTATED	3	2	4	2	4
CRIPAK WILD-TYPE	15	9	17	16	7

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S635. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CRIPAK MUTATED	5	0	5	5
CRIPAK WILD-TYPE	19	14	12	18

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S636. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CRIPAK MUTATED	5	7	3
CRIPAK WILD-TYPE	18	26	19

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S637. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	29	14	21

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S638. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CRIPAK MUTATED	5	2	8
CRIPAK WILD-TYPE	21	8	35

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S639. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	30	16	18

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S640. Gene #80: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CRIPAK MUTATED	8	2	5
CRIPAK WILD-TYPE	33	9	22

'C14ORF180 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S641. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C14ORF180 MUTATED	2	0	1	1	0
C14ORF180 WILD-TYPE	30	23	14	9	9

'C14ORF180 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0794 (Chi-square test), Q value = 1

Table S642. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C14ORF180 MUTATED	0	0	0	1	2
C14ORF180 WILD-TYPE	18	11	21	17	9

'C14ORF180 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S643. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C14ORF180 MUTATED	0	1	1	1
C14ORF180 WILD-TYPE	24	13	16	22

'C14ORF180 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S644. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C14ORF180 MUTATED	0	2	1
C14ORF180 WILD-TYPE	23	31	21

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S645. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C14ORF180 MUTATED	3	0	0
C14ORF180 WILD-TYPE	34	16	26

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S646. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C14ORF180 MUTATED	0	0	3
C14ORF180 WILD-TYPE	26	10	40

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S647. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C14ORF180 MUTATED	3	0	0
C14ORF180 WILD-TYPE	35	18	23

'C14ORF180 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S648. Gene #81: 'C14ORF180 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C14ORF180 MUTATED	2	1	0
C14ORF180 WILD-TYPE	39	10	27

'SPERT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.463 (Chi-square test), Q value = 1

Table S649. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SPERT MUTATED	1	2	2	0	0
SPERT WILD-TYPE	31	21	13	10	9

'SPERT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S650. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SPERT MUTATED	0	1	2	1	0
SPERT WILD-TYPE	18	10	19	17	11

'SPERT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 1

Table S651. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SPERT MUTATED	0	1	3	0
SPERT WILD-TYPE	24	13	14	23

Figure S43. Get High-res Image Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SPERT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S652. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SPERT MUTATED	0	1	3
SPERT WILD-TYPE	23	32	19

'SPERT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S653. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	33	16	26

'SPERT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S654. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SPERT MUTATED	0	0	4
SPERT WILD-TYPE	26	10	39

'SPERT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S655. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	34	18	23

'SPERT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.192 (Fisher's exact test), Q value = 1

Table S656. Gene #82: 'SPERT MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SPERT MUTATED	4	0	0
SPERT WILD-TYPE	37	11	27

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0173 (Chi-square test), Q value = 1

Table S657. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TP53 MUTATED	5	1	5	5	1
TP53 WILD-TYPE	27	22	10	5	8

Figure S44. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.519 (Chi-square test), Q value = 1

Table S658. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TP53 MUTATED	3	3	6	2	1
TP53 WILD-TYPE	15	8	15	16	10

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00344 (Fisher's exact test), Q value = 1

Table S659. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TP53 MUTATED	4	4	7	0
TP53 WILD-TYPE	20	10	10	23

Figure S45. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S660. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TP53 MUTATED	5	3	7
TP53 WILD-TYPE	18	30	15

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00268 (Fisher's exact test), Q value = 1

Table S661. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TP53 MUTATED	10	5	0
TP53 WILD-TYPE	27	11	26

Figure S46. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.07 (Fisher's exact test), Q value = 1

Table S662. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TP53 MUTATED	3	0	12
TP53 WILD-TYPE	23	10	31

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00936 (Fisher's exact test), Q value = 1

Table S663. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TP53 MUTATED	10	5	0
TP53 WILD-TYPE	28	13	23

Figure S47. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0373 (Fisher's exact test), Q value = 1

Table S664. Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TP53 MUTATED	12	0	3
TP53 WILD-TYPE	29	11	24

Figure S48. Get High-res Image Gene #83: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'B3GNT6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.32 (Chi-square test), Q value = 1

Table S665. Gene #84: 'B3GNT6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
B3GNT6 MUTATED	3	0	0	1	0
B3GNT6 WILD-TYPE	29	23	15	9	9

'BHLHE22 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0312 (Chi-square test), Q value = 1

Table S666. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BHLHE22 MUTATED	2	3	5	0	0
BHLHE22 WILD-TYPE	30	20	10	10	9

Figure S49. Get High-res Image Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'BHLHE22 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.27 (Chi-square test), Q value = 1

Table S667. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BHLHE22 MUTATED	0	3	3	3	1
BHLHE22 WILD-TYPE	18	8	18	15	10

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00963 (Fisher's exact test), Q value = 1

Table S668. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BHLHE22 MUTATED	0	5	2	3
BHLHE22 WILD-TYPE	24	9	15	20

Figure S50. Get High-res Image Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'BHLHE22 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S669. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BHLHE22 MUTATED	2	3	5
BHLHE22 WILD-TYPE	21	30	17

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S670. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BHLHE22 MUTATED	4	3	3
BHLHE22 WILD-TYPE	33	13	23

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S671. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BHLHE22 MUTATED	4	1	5
BHLHE22 WILD-TYPE	22	9	38

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S672. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BHLHE22 MUTATED	4	3	3
BHLHE22 WILD-TYPE	34	15	20

'BHLHE22 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S673. Gene #85: 'BHLHE22 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BHLHE22 MUTATED	5	1	4
BHLHE22 WILD-TYPE	36	10	23

'RGMB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.186 (Chi-square test), Q value = 1

Table S674. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RGMB MUTATED	4	2	4	0	0
RGMB WILD-TYPE	28	21	11	10	9

'RGMB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.831 (Chi-square test), Q value = 1

Table S675. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RGMB MUTATED	2	0	2	1	1
RGMB WILD-TYPE	16	11	19	17	10

'RGMB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S676. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RGMB MUTATED	2	1	2	1
RGMB WILD-TYPE	22	13	15	22

'RGMB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S677. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RGMB MUTATED	2	1	3
RGMB WILD-TYPE	21	32	19

'RGMB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S678. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RGMB MUTATED	3	2	1
RGMB WILD-TYPE	34	14	25

'RGMB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S679. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RGMB MUTATED	2	1	3
RGMB WILD-TYPE	24	9	40

'RGMB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S680. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RGMB MUTATED	3	2	1
RGMB WILD-TYPE	35	16	22

'RGMB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S681. Gene #86: 'RGMB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RGMB MUTATED	3	1	2
RGMB WILD-TYPE	38	10	25

'APOE MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0848 (Chi-square test), Q value = 1

Table S682. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
APOE MUTATED	1	3	1	3	0
APOE WILD-TYPE	31	20	14	7	9

'APOE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.342 (Chi-square test), Q value = 1

Table S683. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
APOE MUTATED	1	0	3	3	0
APOE WILD-TYPE	17	11	18	15	11

'APOE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S684. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
APOE MUTATED	2	0	4	1
APOE WILD-TYPE	22	14	13	22

'APOE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S685. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
APOE MUTATED	1	3	3
APOE WILD-TYPE	22	30	19

'APOE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 1

Table S686. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
APOE MUTATED	2	3	2
APOE WILD-TYPE	35	13	24

'APOE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S687. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
APOE MUTATED	4	0	3
APOE WILD-TYPE	22	10	40

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S688. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
APOE MUTATED	2	4	1
APOE WILD-TYPE	36	14	22

'APOE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S689. Gene #87: 'APOE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
APOE MUTATED	3	0	4
APOE WILD-TYPE	38	11	23

'PCGF6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.497 (Chi-square test), Q value = 1

Table S690. Gene #88: 'PCGF6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PCGF6 MUTATED	3	1	0	0	0
PCGF6 WILD-TYPE	29	22	15	10	9

'MEN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.384 (Chi-square test), Q value = 1

Table S691. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MEN1 MUTATED	1	1	2	2	1
MEN1 WILD-TYPE	31	22	13	8	8

'MEN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0105 (Chi-square test), Q value = 1

Table S692. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MEN1 MUTATED	0	3	5	0	0
MEN1 WILD-TYPE	18	8	16	18	11

Figure S51. Get High-res Image Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S693. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MEN1 MUTATED	1	2	4	1
MEN1 WILD-TYPE	23	12	13	22

'MEN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.014 (Fisher's exact test), Q value = 1

Table S694. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MEN1 MUTATED	1	1	6
MEN1 WILD-TYPE	22	32	16

Figure S52. Get High-res Image Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S695. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MEN1 MUTATED	5	2	1
MEN1 WILD-TYPE	32	14	25

'MEN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S696. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MEN1 MUTATED	1	1	6
MEN1 WILD-TYPE	25	9	37

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S697. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MEN1 MUTATED	5	2	1
MEN1 WILD-TYPE	33	16	22

'MEN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S698. Gene #89: 'MEN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MEN1 MUTATED	6	1	1
MEN1 WILD-TYPE	35	10	26

'LZTR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.241 (Chi-square test), Q value = 1

Table S699. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LZTR1 MUTATED	5	0	1	1	0
LZTR1 WILD-TYPE	27	23	14	9	9

'LZTR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.305 (Chi-square test), Q value = 1

Table S700. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LZTR1 MUTATED	3	0	1	1	0
LZTR1 WILD-TYPE	15	11	20	17	11

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 1

Table S701. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LZTR1 MUTATED	4	1	0	0
LZTR1 WILD-TYPE	20	13	17	23

'LZTR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S702. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LZTR1 MUTATED	3	1	1
LZTR1 WILD-TYPE	20	32	21

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S703. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LZTR1 MUTATED	4	1	0
LZTR1 WILD-TYPE	33	15	26

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S704. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LZTR1 MUTATED	0	0	5
LZTR1 WILD-TYPE	26	10	38

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S705. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LZTR1 MUTATED	4	1	0
LZTR1 WILD-TYPE	34	17	23

'LZTR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S706. Gene #90: 'LZTR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LZTR1 MUTATED	4	0	1
LZTR1 WILD-TYPE	37	11	26

'RASIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.337 (Chi-square test), Q value = 1

Table S707. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RASIP1 MUTATED	4	2	4	0	1
RASIP1 WILD-TYPE	28	21	11	10	8

'RASIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.735 (Chi-square test), Q value = 1

Table S708. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RASIP1 MUTATED	3	2	4	1	1
RASIP1 WILD-TYPE	15	9	17	17	10

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 1

Table S709. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RASIP1 MUTATED	4	4	3	0
RASIP1 WILD-TYPE	20	10	14	23

Figure S53. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 1

Table S710. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RASIP1 MUTATED	4	2	5
RASIP1 WILD-TYPE	19	31	17

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0118 (Fisher's exact test), Q value = 1

Table S711. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RASIP1 MUTATED	4	6	1
RASIP1 WILD-TYPE	33	10	25

Figure S54. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S712. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RASIP1 MUTATED	6	0	5
RASIP1 WILD-TYPE	20	10	38

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00128 (Fisher's exact test), Q value = 1

Table S713. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RASIP1 MUTATED	4	7	0
RASIP1 WILD-TYPE	34	11	23

Figure S55. Get High-res Image Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'RASIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S714. Gene #91: 'RASIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RASIP1 MUTATED	5	0	6
RASIP1 WILD-TYPE	36	11	21

'ZC3H12D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0274 (Chi-square test), Q value = 1

Table S715. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZC3H12D MUTATED	2	0	1	3	0
ZC3H12D WILD-TYPE	30	23	14	7	9

Figure S56. Get High-res Image Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ZC3H12D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S716. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ZC3H12D MUTATED	1	0	2	1	1
ZC3H12D WILD-TYPE	17	11	19	17	10

'ZC3H12D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S717. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ZC3H12D MUTATED	1	1	2	1
ZC3H12D WILD-TYPE	23	13	15	22

'ZC3H12D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S718. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ZC3H12D MUTATED	1	1	3
ZC3H12D WILD-TYPE	22	32	19

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S719. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ZC3H12D MUTATED	4	0	1
ZC3H12D WILD-TYPE	33	16	25

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S720. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ZC3H12D MUTATED	0	1	4
ZC3H12D WILD-TYPE	26	9	39

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S721. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ZC3H12D MUTATED	4	0	1
ZC3H12D WILD-TYPE	34	18	22

'ZC3H12D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 1

Table S722. Gene #92: 'ZC3H12D MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ZC3H12D MUTATED	3	2	0
ZC3H12D WILD-TYPE	38	9	27

'TSC22D2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.372 (Chi-square test), Q value = 1

Table S723. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
TSC22D2 MUTATED	4	1	2	3	1
TSC22D2 WILD-TYPE	28	22	13	7	8

'TSC22D2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.275 (Chi-square test), Q value = 1

Table S724. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
TSC22D2 MUTATED	2	0	5	1	2
TSC22D2 WILD-TYPE	16	11	16	17	9

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S725. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
TSC22D2 MUTATED	3	1	3	3
TSC22D2 WILD-TYPE	21	13	14	20

'TSC22D2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S726. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
TSC22D2 MUTATED	2	4	4
TSC22D2 WILD-TYPE	21	29	18

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S727. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
TSC22D2 MUTATED	5	2	3
TSC22D2 WILD-TYPE	32	14	23

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S728. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
TSC22D2 MUTATED	3	0	7
TSC22D2 WILD-TYPE	23	10	36

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S729. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
TSC22D2 MUTATED	5	2	3
TSC22D2 WILD-TYPE	33	16	20

'TSC22D2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S730. Gene #93: 'TSC22D2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
TSC22D2 MUTATED	6	0	4
TSC22D2 WILD-TYPE	35	11	23

'COQ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.081 (Chi-square test), Q value = 1

Table S731. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
COQ2 MUTATED	1	1	1	3	1
COQ2 WILD-TYPE	31	22	14	7	8

'COQ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Chi-square test), Q value = 1

Table S732. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
COQ2 MUTATED	1	1	1	1	2
COQ2 WILD-TYPE	17	10	20	17	9

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S733. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
COQ2 MUTATED	1	2	2	1
COQ2 WILD-TYPE	23	12	15	22

'COQ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S734. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
COQ2 MUTATED	1	2	3
COQ2 WILD-TYPE	22	31	19

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S735. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
COQ2 MUTATED	3	2	1
COQ2 WILD-TYPE	34	14	25

'COQ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S736. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
COQ2 MUTATED	3	0	3
COQ2 WILD-TYPE	23	10	40

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S737. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
COQ2 MUTATED	3	2	1
COQ2 WILD-TYPE	35	16	22

'COQ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S738. Gene #94: 'COQ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
COQ2 MUTATED	3	0	3
COQ2 WILD-TYPE	38	11	24

'DLEU7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.218 (Chi-square test), Q value = 1

Table S739. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DLEU7 MUTATED	4	0	2	0	0
DLEU7 WILD-TYPE	28	23	13	10	9

'DLEU7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.788 (Chi-square test), Q value = 1

Table S740. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DLEU7 MUTATED	1	1	1	0	1
DLEU7 WILD-TYPE	17	10	20	18	10

'DLEU7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S741. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DLEU7 MUTATED	2	1	1	0
DLEU7 WILD-TYPE	22	13	16	23

'DLEU7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S742. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DLEU7 MUTATED	2	0	2
DLEU7 WILD-TYPE	21	33	20

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S743. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DLEU7 MUTATED	3	1	0
DLEU7 WILD-TYPE	34	15	26

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S744. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DLEU7 MUTATED	1	0	3
DLEU7 WILD-TYPE	25	10	40

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S745. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DLEU7 MUTATED	3	1	0
DLEU7 WILD-TYPE	35	17	23

'DLEU7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S746. Gene #95: 'DLEU7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DLEU7 MUTATED	3	0	1
DLEU7 WILD-TYPE	38	11	26

'FAM46A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S747. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FAM46A MUTATED	1	2	1	0	0
FAM46A WILD-TYPE	31	21	14	10	9

'FAM46A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S748. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FAM46A MUTATED	1	0	1	1	0
FAM46A WILD-TYPE	17	11	20	17	11

'FAM46A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S749. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FAM46A MUTATED	1	1	0	1
FAM46A WILD-TYPE	23	13	17	22

'FAM46A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S750. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FAM46A MUTATED	1	1	1
FAM46A WILD-TYPE	22	32	21

'FAM46A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S751. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	35	16	25

'FAM46A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S752. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FAM46A MUTATED	1	0	2
FAM46A WILD-TYPE	25	10	41

'FAM46A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S753. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	36	18	22

'FAM46A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S754. Gene #96: 'FAM46A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FAM46A MUTATED	2	0	1
FAM46A WILD-TYPE	39	11	26

'JMJD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.634 (Chi-square test), Q value = 1

Table S755. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
JMJD4 MUTATED	2	2	2	0	0
JMJD4 WILD-TYPE	30	21	13	10	9

'JMJD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.177 (Chi-square test), Q value = 1

Table S756. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
JMJD4 MUTATED	3	0	2	0	0
JMJD4 WILD-TYPE	15	11	19	18	11

'JMJD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S757. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
JMJD4 MUTATED	3	1	1	0
JMJD4 WILD-TYPE	21	13	16	23

'JMJD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S758. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	20	32	21

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S759. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	34	15	25

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S760. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
JMJD4 MUTATED	1	1	3
JMJD4 WILD-TYPE	25	9	40

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S761. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	35	17	22

'JMJD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S762. Gene #97: 'JMJD4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
JMJD4 MUTATED	3	1	1
JMJD4 WILD-TYPE	38	10	26

'DOK7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Chi-square test), Q value = 1

Table S763. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DOK7 MUTATED	2	1	1	2	1
DOK7 WILD-TYPE	30	22	14	8	8

'DOK7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.373 (Chi-square test), Q value = 1

Table S764. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DOK7 MUTATED	1	0	4	1	1
DOK7 WILD-TYPE	17	11	17	17	10

'DOK7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S765. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DOK7 MUTATED	2	1	2	2
DOK7 WILD-TYPE	22	13	15	21

'DOK7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S766. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DOK7 MUTATED	2	3	2
DOK7 WILD-TYPE	21	30	20

'DOK7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S767. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DOK7 MUTATED	3	1	3
DOK7 WILD-TYPE	34	15	23

'DOK7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0198 (Fisher's exact test), Q value = 1

Table S768. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DOK7 MUTATED	0	3	4
DOK7 WILD-TYPE	26	7	39

Figure S57. Get High-res Image Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'DOK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S769. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DOK7 MUTATED	3	1	3
DOK7 WILD-TYPE	35	17	20

'DOK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.02 (Fisher's exact test), Q value = 1

Table S770. Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DOK7 MUTATED	4	3	0
DOK7 WILD-TYPE	37	8	27

Figure S58. Get High-res Image Gene #98: 'DOK7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'KNDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.775 (Chi-square test), Q value = 1

Table S771. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KNDC1 MUTATED	4	4	3	3	2
KNDC1 WILD-TYPE	28	19	12	7	7

'KNDC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0847 (Chi-square test), Q value = 1

Table S772. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KNDC1 MUTATED	1	2	4	2	5
KNDC1 WILD-TYPE	17	9	17	16	6

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S773. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KNDC1 MUTATED	3	4	2	5
KNDC1 WILD-TYPE	21	10	15	18

'KNDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S774. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KNDC1 MUTATED	3	8	3
KNDC1 WILD-TYPE	20	25	19

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S775. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KNDC1 MUTATED	5	3	6
KNDC1 WILD-TYPE	32	13	20

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S776. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KNDC1 MUTATED	6	2	6
KNDC1 WILD-TYPE	20	8	37

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S777. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KNDC1 MUTATED	5	4	5
KNDC1 WILD-TYPE	33	14	18

'KNDC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S778. Gene #99: 'KNDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KNDC1 MUTATED	6	2	6
KNDC1 WILD-TYPE	35	9	21

'SIX6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00409 (Chi-square test), Q value = 1

Table S779. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SIX6 MUTATED	0	0	3	0	0
SIX6 WILD-TYPE	32	23	12	10	9

Figure S59. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SIX6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0715 (Chi-square test), Q value = 1

Table S780. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SIX6 MUTATED	0	0	3	0	0
SIX6 WILD-TYPE	18	11	18	18	11

'SIX6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00478 (Fisher's exact test), Q value = 1

Table S781. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SIX6 MUTATED	0	3	0	0
SIX6 WILD-TYPE	24	11	17	23

Figure S60. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SIX6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0202 (Fisher's exact test), Q value = 1

Table S782. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SIX6 MUTATED	0	0	3
SIX6 WILD-TYPE	23	33	19

Figure S61. Get High-res Image Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'SIX6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 1

Table S783. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	34	16	26

'SIX6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S784. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SIX6 MUTATED	0	0	3
SIX6 WILD-TYPE	26	10	40

'SIX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S785. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	35	18	23

'SIX6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S786. Gene #100: 'SIX6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SIX6 MUTATED	3	0	0
SIX6 WILD-TYPE	38	11	27

'PDCD6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0684 (Chi-square test), Q value = 1

Table S787. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PDCD6 MUTATED	0	1	3	1	0
PDCD6 WILD-TYPE	32	22	12	9	9

'PDCD6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.482 (Chi-square test), Q value = 1

Table S788. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PDCD6 MUTATED	1	0	1	1	2
PDCD6 WILD-TYPE	17	11	20	17	9

'PDCD6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S789. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PDCD6 MUTATED	0	1	2	1
PDCD6 WILD-TYPE	24	13	15	22

'PDCD6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S790. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PDCD6 MUTATED	0	2	2
PDCD6 WILD-TYPE	23	31	20

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S791. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	33	16	25

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S792. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PDCD6 MUTATED	1	0	4
PDCD6 WILD-TYPE	25	10	39

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S793. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	34	18	22

'PDCD6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S794. Gene #101: 'PDCD6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PDCD6 MUTATED	4	0	1
PDCD6 WILD-TYPE	37	11	26

'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.292 (Chi-square test), Q value = 1

Table S795. Gene #102: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HNRNPCL1 MUTATED	3	0	0	0	1
HNRNPCL1 WILD-TYPE	29	23	15	10	8

'ATP6V0E2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Chi-square test), Q value = 1

Table S796. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATP6V0E2 MUTATED	2	1	0	1	0
ATP6V0E2 WILD-TYPE	30	22	15	9	9

'ATP6V0E2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S797. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATP6V0E2 MUTATED	1	0	2	1	0
ATP6V0E2 WILD-TYPE	17	11	19	17	11

'ATP6V0E2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S798. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATP6V0E2 MUTATED	1	0	2	1
ATP6V0E2 WILD-TYPE	23	14	15	22

'ATP6V0E2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S799. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATP6V0E2 MUTATED	1	3	0
ATP6V0E2 WILD-TYPE	22	30	22

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0883 (Fisher's exact test), Q value = 1

Table S800. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATP6V0E2 MUTATED	0	1	3
ATP6V0E2 WILD-TYPE	37	15	23

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S801. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATP6V0E2 MUTATED	2	1	1
ATP6V0E2 WILD-TYPE	24	9	42

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S802. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATP6V0E2 MUTATED	1	0	3
ATP6V0E2 WILD-TYPE	37	18	20

'ATP6V0E2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S803. Gene #103: 'ATP6V0E2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATP6V0E2 MUTATED	1	1	2
ATP6V0E2 WILD-TYPE	40	10	25

'HES3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S804. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HES3 MUTATED	3	1	1	2	0
HES3 WILD-TYPE	29	22	14	8	9

'HES3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.794 (Chi-square test), Q value = 1

Table S805. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HES3 MUTATED	2	0	1	1	1
HES3 WILD-TYPE	16	11	20	17	10

'HES3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S806. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HES3 MUTATED	3	1	0	1
HES3 WILD-TYPE	21	13	17	22

'HES3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S807. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HES3 MUTATED	3	1	1
HES3 WILD-TYPE	20	32	21

'HES3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 1

Table S808. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HES3 MUTATED	3	2	0
HES3 WILD-TYPE	34	14	26

'HES3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S809. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HES3 MUTATED	2	0	3
HES3 WILD-TYPE	24	10	40

'HES3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S810. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HES3 MUTATED	3	2	0
HES3 WILD-TYPE	35	16	23

'HES3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S811. Gene #104: 'HES3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HES3 MUTATED	3	0	2
HES3 WILD-TYPE	38	11	25

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.518 (Chi-square test), Q value = 1

Table S812. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AATK MUTATED	1	4	2	1	1
AATK WILD-TYPE	31	19	13	9	8

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.32 (Chi-square test), Q value = 1

Table S813. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AATK MUTATED	1	1	4	0	1
AATK WILD-TYPE	17	10	17	18	10

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S814. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AATK MUTATED	1	2	2	2
AATK WILD-TYPE	23	12	15	21

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S815. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AATK MUTATED	1	2	4
AATK WILD-TYPE	22	31	18

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S816. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AATK MUTATED	4	1	2
AATK WILD-TYPE	33	15	24

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S817. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AATK MUTATED	3	0	4
AATK WILD-TYPE	23	10	39

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S818. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AATK MUTATED	4	1	2
AATK WILD-TYPE	34	17	21

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S819. Gene #105: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AATK MUTATED	4	0	3
AATK WILD-TYPE	37	11	24

'FANK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.863 (Chi-square test), Q value = 1

Table S820. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FANK1 MUTATED	2	1	1	0	0
FANK1 WILD-TYPE	30	22	14	10	9

'FANK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.496 (Chi-square test), Q value = 1

Table S821. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FANK1 MUTATED	0	1	0	1	1
FANK1 WILD-TYPE	18	10	21	17	10

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S822. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FANK1 MUTATED	1	1	0	1
FANK1 WILD-TYPE	23	13	17	22

'FANK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S823. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FANK1 MUTATED	1	2	0
FANK1 WILD-TYPE	22	31	22

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S824. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	36	15	25

'FANK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S825. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FANK1 MUTATED	0	1	2
FANK1 WILD-TYPE	26	9	41

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S826. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FANK1 MUTATED	1	1	1
FANK1 WILD-TYPE	37	17	22

'FANK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S827. Gene #106: 'FANK1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FANK1 MUTATED	2	1	0
FANK1 WILD-TYPE	39	10	27

'FEZ2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.809 (Chi-square test), Q value = 1

Table S828. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FEZ2 MUTATED	2	2	1	0	0
FEZ2 WILD-TYPE	30	21	14	10	9

'FEZ2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.982 (Chi-square test), Q value = 1

Table S829. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FEZ2 MUTATED	1	1	1	1	1
FEZ2 WILD-TYPE	17	10	20	17	10

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S830. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FEZ2 MUTATED	1	1	0	3
FEZ2 WILD-TYPE	23	13	17	20

'FEZ2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S831. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FEZ2 MUTATED	2	3	0
FEZ2 WILD-TYPE	21	30	22

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S832. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	36	14	24

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S833. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FEZ2 MUTATED	2	1	2
FEZ2 WILD-TYPE	24	9	41

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S834. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	37	16	21

'FEZ2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S835. Gene #107: 'FEZ2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FEZ2 MUTATED	1	2	2
FEZ2 WILD-TYPE	40	9	25

'HSD17B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.809 (Chi-square test), Q value = 1

Table S836. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
HSD17B1 MUTATED	2	2	1	0	0
HSD17B1 WILD-TYPE	30	21	14	10	9

'HSD17B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.246 (Chi-square test), Q value = 1

Table S837. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
HSD17B1 MUTATED	0	0	1	3	1
HSD17B1 WILD-TYPE	18	11	20	15	10

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S838. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
HSD17B1 MUTATED	2	1	1	1
HSD17B1 WILD-TYPE	22	13	16	22

'HSD17B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 1

Table S839. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
HSD17B1 MUTATED	0	4	1
HSD17B1 WILD-TYPE	23	29	21

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S840. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
HSD17B1 MUTATED	2	2	1
HSD17B1 WILD-TYPE	35	14	25

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S841. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
HSD17B1 MUTATED	2	0	3
HSD17B1 WILD-TYPE	24	10	40

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S842. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
HSD17B1 MUTATED	2	2	1
HSD17B1 WILD-TYPE	36	16	22

'HSD17B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S843. Gene #108: 'HSD17B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
HSD17B1 MUTATED	2	0	3
HSD17B1 WILD-TYPE	39	11	24

'PRKAR1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Chi-square test), Q value = 1

Table S844. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRKAR1A MUTATED	2	1	1	2	1
PRKAR1A WILD-TYPE	30	22	14	8	8

'PRKAR1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.794 (Chi-square test), Q value = 1

Table S845. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRKAR1A MUTATED	1	1	2	1	2
PRKAR1A WILD-TYPE	17	10	19	17	9

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 1

Table S846. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRKAR1A MUTATED	2	1	4	0
PRKAR1A WILD-TYPE	22	13	13	23

'PRKAR1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S847. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRKAR1A MUTATED	1	3	3
PRKAR1A WILD-TYPE	22	30	19

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S848. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRKAR1A MUTATED	5	1	1
PRKAR1A WILD-TYPE	32	15	25

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S849. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRKAR1A MUTATED	2	0	5
PRKAR1A WILD-TYPE	24	10	38

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S850. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRKAR1A MUTATED	5	2	0
PRKAR1A WILD-TYPE	33	16	23

'PRKAR1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S851. Gene #109: 'PRKAR1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRKAR1A MUTATED	5	0	2
PRKAR1A WILD-TYPE	36	11	25

'ATOH8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S852. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ATOH8 MUTATED	2	0	1	1	0
ATOH8 WILD-TYPE	30	23	14	9	9

'ATOH8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S853. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ATOH8 MUTATED	0	0	1	1	1
ATOH8 WILD-TYPE	18	11	20	17	10

'ATOH8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S854. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ATOH8 MUTATED	1	0	1	1
ATOH8 WILD-TYPE	23	14	16	22

'ATOH8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S855. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ATOH8 MUTATED	1	1	1
ATOH8 WILD-TYPE	22	32	21

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S856. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ATOH8 MUTATED	2	0	1
ATOH8 WILD-TYPE	35	16	25

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S857. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ATOH8 MUTATED	0	1	2
ATOH8 WILD-TYPE	26	9	41

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S858. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ATOH8 MUTATED	2	0	1
ATOH8 WILD-TYPE	36	18	22

'ATOH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S859. Gene #110: 'ATOH8 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ATOH8 MUTATED	2	1	0
ATOH8 WILD-TYPE	39	10	27

'BTBD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.498 (Chi-square test), Q value = 1

Table S860. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BTBD11 MUTATED	2	3	3	1	0
BTBD11 WILD-TYPE	30	20	12	9	9

'BTBD11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S861. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BTBD11 MUTATED	2	1	2	1	2
BTBD11 WILD-TYPE	16	10	19	17	9

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S862. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BTBD11 MUTATED	1	1	4	2
BTBD11 WILD-TYPE	23	13	13	21

'BTBD11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S863. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BTBD11 MUTATED	1	3	4
BTBD11 WILD-TYPE	22	30	18

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S864. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	32	15	24

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S865. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BTBD11 MUTATED	2	1	5
BTBD11 WILD-TYPE	24	9	38

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S866. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	33	17	21

'BTBD11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S867. Gene #111: 'BTBD11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BTBD11 MUTATED	5	1	2
BTBD11 WILD-TYPE	36	10	25

'KANK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0378 (Chi-square test), Q value = 1

Table S868. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KANK3 MUTATED	0	1	3	2	0
KANK3 WILD-TYPE	32	22	12	8	9

Figure S62. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KANK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.532 (Chi-square test), Q value = 1

Table S869. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KANK3 MUTATED	2	0	2	0	1
KANK3 WILD-TYPE	16	11	19	18	10

'KANK3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.048 (Fisher's exact test), Q value = 1

Table S870. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KANK3 MUTATED	1	3	1	0
KANK3 WILD-TYPE	23	11	16	23

Figure S63. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'KANK3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0108 (Fisher's exact test), Q value = 1

Table S871. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KANK3 MUTATED	1	0	4
KANK3 WILD-TYPE	22	33	18

Figure S64. Get High-res Image Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'KANK3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0573 (Fisher's exact test), Q value = 1

Table S872. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KANK3 MUTATED	2	3	0
KANK3 WILD-TYPE	35	13	26

'KANK3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S873. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KANK3 MUTATED	2	0	3
KANK3 WILD-TYPE	24	10	40

'KANK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 1

Table S874. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KANK3 MUTATED	2	3	0
KANK3 WILD-TYPE	36	15	23

'KANK3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S875. Gene #112: 'KANK3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KANK3 MUTATED	3	0	2
KANK3 WILD-TYPE	38	11	25

'PAQR4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S876. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PAQR4 MUTATED	1	1	1	0	0
PAQR4 WILD-TYPE	31	22	14	10	9

'PAQR4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Chi-square test), Q value = 1

Table S877. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PAQR4 MUTATED	1	0	1	1	0
PAQR4 WILD-TYPE	17	11	20	17	11

'PAQR4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S878. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PAQR4 MUTATED	1	1	0	1
PAQR4 WILD-TYPE	23	13	17	22

'PAQR4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S879. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PAQR4 MUTATED	1	1	1
PAQR4 WILD-TYPE	22	32	21

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S880. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PAQR4 MUTATED	1	1	1
PAQR4 WILD-TYPE	36	15	25

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S881. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PAQR4 MUTATED	1	0	2
PAQR4 WILD-TYPE	25	10	41

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S882. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PAQR4 MUTATED	2	0	1
PAQR4 WILD-TYPE	36	18	22

'PAQR4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S883. Gene #113: 'PAQR4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PAQR4 MUTATED	2	0	1
PAQR4 WILD-TYPE	39	11	26

'NOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.768 (Chi-square test), Q value = 1

Table S884. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NOM1 MUTATED	2	3	1	1	0
NOM1 WILD-TYPE	30	20	14	9	9

'NOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.691 (Chi-square test), Q value = 1

Table S885. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NOM1 MUTATED	1	1	1	1	2
NOM1 WILD-TYPE	17	10	20	17	9

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S886. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NOM1 MUTATED	2	0	1	3
NOM1 WILD-TYPE	22	14	16	20

'NOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S887. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NOM1 MUTATED	2	3	1
NOM1 WILD-TYPE	21	30	21

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S888. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	35	15	23

'NOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S889. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	24	9	40

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S890. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NOM1 MUTATED	2	1	3
NOM1 WILD-TYPE	36	17	20

'NOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S891. Gene #114: 'NOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NOM1 MUTATED	3	1	2
NOM1 WILD-TYPE	38	10	25

'PLIN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.152 (Chi-square test), Q value = 1

Table S892. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PLIN5 MUTATED	1	4	0	1	0
PLIN5 WILD-TYPE	31	19	15	9	9

'PLIN5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.505 (Chi-square test), Q value = 1

Table S893. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PLIN5 MUTATED	1	2	1	2	0
PLIN5 WILD-TYPE	17	9	20	16	11

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S894. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PLIN5 MUTATED	1	1	2	2
PLIN5 WILD-TYPE	23	13	15	21

'PLIN5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S895. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PLIN5 MUTATED	1	2	3
PLIN5 WILD-TYPE	22	31	19

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S896. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PLIN5 MUTATED	1	2	3
PLIN5 WILD-TYPE	36	14	23

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0402 (Fisher's exact test), Q value = 1

Table S897. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PLIN5 MUTATED	5	0	1
PLIN5 WILD-TYPE	21	10	42

Figure S65. Get High-res Image Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S898. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PLIN5 MUTATED	1	3	2
PLIN5 WILD-TYPE	37	15	21

'PLIN5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0391 (Fisher's exact test), Q value = 1

Table S899. Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PLIN5 MUTATED	1	0	5
PLIN5 WILD-TYPE	40	11	22

Figure S66. Get High-res Image Gene #115: 'PLIN5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CD320 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.72 (Chi-square test), Q value = 1

Table S900. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CD320 MUTATED	3	1	1	0	0
CD320 WILD-TYPE	29	22	14	10	9

'CD320 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S901. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CD320 MUTATED	2	0	1	2	0
CD320 WILD-TYPE	16	11	20	16	11

'CD320 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S902. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CD320 MUTATED	2	0	2	1
CD320 WILD-TYPE	22	14	15	22

'CD320 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S903. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CD320 MUTATED	2	2	1
CD320 WILD-TYPE	21	31	21

'CD320 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S904. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CD320 MUTATED	4	1	0
CD320 WILD-TYPE	33	15	26

'CD320 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S905. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CD320 MUTATED	0	0	5
CD320 WILD-TYPE	26	10	38

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0756 (Fisher's exact test), Q value = 1

Table S906. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CD320 MUTATED	5	0	0
CD320 WILD-TYPE	33	18	23

'CD320 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S907. Gene #116: 'CD320 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CD320 MUTATED	5	0	0
CD320 WILD-TYPE	36	11	27

'AVL9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.25 (Chi-square test), Q value = 1

Table S908. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
AVL9 MUTATED	2	2	0	0	2
AVL9 WILD-TYPE	30	21	15	10	7

'AVL9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.381 (Chi-square test), Q value = 1

Table S909. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
AVL9 MUTATED	2	1	0	0	1
AVL9 WILD-TYPE	16	10	21	18	10

'AVL9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S910. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
AVL9 MUTATED	2	0	1	1
AVL9 WILD-TYPE	22	14	16	22

'AVL9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S911. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	21	32	21

'AVL9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S912. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	35	15	25

'AVL9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S913. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
AVL9 MUTATED	1	1	2
AVL9 WILD-TYPE	25	9	41

'AVL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S914. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	36	17	22

'AVL9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S915. Gene #117: 'AVL9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
AVL9 MUTATED	2	1	1
AVL9 WILD-TYPE	39	10	26

'ASB16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.808 (Chi-square test), Q value = 1

Table S916. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ASB16 MUTATED	3	3	1	1	2
ASB16 WILD-TYPE	29	20	14	9	7

'ASB16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.947 (Chi-square test), Q value = 1

Table S917. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ASB16 MUTATED	2	1	1	1	1
ASB16 WILD-TYPE	16	10	20	17	10

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S918. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ASB16 MUTATED	2	1	0	3
ASB16 WILD-TYPE	22	13	17	20

'ASB16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S919. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ASB16 MUTATED	2	3	1
ASB16 WILD-TYPE	21	30	21

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S920. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	34	15	24

'ASB16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S921. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ASB16 MUTATED	2	1	3
ASB16 WILD-TYPE	24	9	40

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S922. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	35	17	21

'ASB16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S923. Gene #118: 'ASB16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ASB16 MUTATED	3	1	2
ASB16 WILD-TYPE	38	10	25

'SCRT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.616 (Chi-square test), Q value = 1

Table S924. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SCRT1 MUTATED	1	2	2	1	0
SCRT1 WILD-TYPE	31	21	13	9	9

'SCRT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.345 (Chi-square test), Q value = 1

Table S925. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
SCRT1 MUTATED	3	0	1	2	0
SCRT1 WILD-TYPE	15	11	20	16	11

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S926. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
SCRT1 MUTATED	2	2	1	1
SCRT1 WILD-TYPE	22	12	16	22

'SCRT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S927. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
SCRT1 MUTATED	2	2	2
SCRT1 WILD-TYPE	21	31	20

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S928. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
SCRT1 MUTATED	3	2	1
SCRT1 WILD-TYPE	34	14	25

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S929. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
SCRT1 MUTATED	3	0	3
SCRT1 WILD-TYPE	23	10	40

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S930. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
SCRT1 MUTATED	3	2	1
SCRT1 WILD-TYPE	35	16	22

'SCRT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S931. Gene #119: 'SCRT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
SCRT1 MUTATED	3	0	3
SCRT1 WILD-TYPE	38	11	24

'FOXQ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0765 (Chi-square test), Q value = 1

Table S932. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FOXQ1 MUTATED	1	0	0	2	1
FOXQ1 WILD-TYPE	31	23	15	8	8

'FOXQ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0866 (Chi-square test), Q value = 1

Table S933. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FOXQ1 MUTATED	0	0	1	0	2
FOXQ1 WILD-TYPE	18	11	20	18	9

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S934. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FOXQ1 MUTATED	1	0	1	1
FOXQ1 WILD-TYPE	23	14	16	22

'FOXQ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S935. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FOXQ1 MUTATED	1	2	0
FOXQ1 WILD-TYPE	22	31	22

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S936. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FOXQ1 MUTATED	1	0	2
FOXQ1 WILD-TYPE	36	16	24

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S937. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FOXQ1 MUTATED	2	0	1
FOXQ1 WILD-TYPE	24	10	42

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S938. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FOXQ1 MUTATED	1	1	1
FOXQ1 WILD-TYPE	37	17	22

'FOXQ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S939. Gene #120: 'FOXQ1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FOXQ1 MUTATED	1	0	2
FOXQ1 WILD-TYPE	40	11	25

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.101 (Chi-square test), Q value = 1

Table S940. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
NPTX1 MUTATED	5	0	0	0	1
NPTX1 WILD-TYPE	27	23	15	10	8

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Chi-square test), Q value = 1

Table S941. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
NPTX1 MUTATED	1	1	1	3	0
NPTX1 WILD-TYPE	17	10	20	15	11

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S942. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
NPTX1 MUTATED	2	0	1	3
NPTX1 WILD-TYPE	22	14	16	20

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 1

Table S943. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
NPTX1 MUTATED	2	4	0
NPTX1 WILD-TYPE	21	29	22

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S944. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
NPTX1 MUTATED	3	0	3
NPTX1 WILD-TYPE	34	16	23

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 1

Table S945. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
NPTX1 MUTATED	1	2	3
NPTX1 WILD-TYPE	25	8	40

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S946. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
NPTX1 MUTATED	3	0	3
NPTX1 WILD-TYPE	35	18	20

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0522 (Fisher's exact test), Q value = 1

Table S947. Gene #121: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
NPTX1 MUTATED	2	3	1
NPTX1 WILD-TYPE	39	8	26

'ZNF285 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.526 (Chi-square test), Q value = 1

Table S948. Gene #122: 'ZNF285 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ZNF285 MUTATED	1	2	0	0	0
ZNF285 WILD-TYPE	31	21	15	10	9

'PTPLA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.243 (Chi-square test), Q value = 1

Table S949. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PTPLA MUTATED	3	0	1	2	0
PTPLA WILD-TYPE	29	23	14	8	9

'PTPLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S950. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PTPLA MUTATED	1	1	3	0	0
PTPLA WILD-TYPE	17	10	18	18	11

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S951. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PTPLA MUTATED	2	0	2	1
PTPLA WILD-TYPE	22	14	15	22

'PTPLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S952. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PTPLA MUTATED	2	1	2
PTPLA WILD-TYPE	21	32	20

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S953. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PTPLA MUTATED	2	1	2
PTPLA WILD-TYPE	35	15	24

'PTPLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S954. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PTPLA MUTATED	2	0	3
PTPLA WILD-TYPE	24	10	40

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S955. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PTPLA MUTATED	2	2	1
PTPLA WILD-TYPE	36	16	22

'PTPLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S956. Gene #123: 'PTPLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PTPLA MUTATED	3	0	2
PTPLA WILD-TYPE	38	11	25

'PRSS27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.439 (Chi-square test), Q value = 1

Table S957. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRSS27 MUTATED	1	1	2	0	0
PRSS27 WILD-TYPE	31	22	13	10	9

'PRSS27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S958. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRSS27 MUTATED	0	1	2	1	0
PRSS27 WILD-TYPE	18	10	19	17	11

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S959. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRSS27 MUTATED	1	2	1	0
PRSS27 WILD-TYPE	23	12	16	23

'PRSS27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S960. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRSS27 MUTATED	0	1	3
PRSS27 WILD-TYPE	23	32	19

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S961. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRSS27 MUTATED	2	2	0
PRSS27 WILD-TYPE	35	14	26

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S962. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRSS27 MUTATED	1	0	3
PRSS27 WILD-TYPE	25	10	40

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S963. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRSS27 MUTATED	2	2	0
PRSS27 WILD-TYPE	36	16	23

'PRSS27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S964. Gene #124: 'PRSS27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRSS27 MUTATED	2	0	2
PRSS27 WILD-TYPE	39	11	25

'LRRN4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.838 (Chi-square test), Q value = 1

Table S965. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LRRN4 MUTATED	1	1	1	1	0
LRRN4 WILD-TYPE	31	22	14	9	9

'LRRN4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.51 (Chi-square test), Q value = 1

Table S966. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
LRRN4 MUTATED	0	0	1	2	1
LRRN4 WILD-TYPE	18	11	20	16	10

'LRRN4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S967. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
LRRN4 MUTATED	2	1	0	1
LRRN4 WILD-TYPE	22	13	17	22

'LRRN4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S968. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
LRRN4 MUTATED	1	2	1
LRRN4 WILD-TYPE	22	31	21

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S969. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
LRRN4 MUTATED	3	1	0
LRRN4 WILD-TYPE	34	15	26

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S970. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
LRRN4 MUTATED	0	0	4
LRRN4 WILD-TYPE	26	10	39

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S971. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
LRRN4 MUTATED	3	1	0
LRRN4 WILD-TYPE	35	17	23

'LRRN4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S972. Gene #125: 'LRRN4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
LRRN4 MUTATED	3	0	1
LRRN4 WILD-TYPE	38	11	26

'EP400 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S973. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
EP400 MUTATED	1	1	1	0	0
EP400 WILD-TYPE	31	22	14	10	9

'EP400 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.725 (Chi-square test), Q value = 1

Table S974. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
EP400 MUTATED	1	0	2	1	0
EP400 WILD-TYPE	17	11	19	17	11

'EP400 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S975. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
EP400 MUTATED	1	2	0	1
EP400 WILD-TYPE	23	12	17	22

'EP400 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S976. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
EP400 MUTATED	1	1	2
EP400 WILD-TYPE	22	32	20

'EP400 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S977. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
EP400 MUTATED	2	1	1
EP400 WILD-TYPE	35	15	25

'EP400 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S978. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
EP400 MUTATED	2	0	2
EP400 WILD-TYPE	24	10	41

'EP400 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S979. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
EP400 MUTATED	2	1	1
EP400 WILD-TYPE	36	17	22

'EP400 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S980. Gene #126: 'EP400 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
EP400 MUTATED	2	0	2
EP400 WILD-TYPE	39	11	25

'LTK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.863 (Chi-square test), Q value = 1

Table S981. Gene #127: 'LTK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
LTK MUTATED	2	1	1	0	0
LTK WILD-TYPE	30	22	14	10	9

'CCDC96 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.103 (Chi-square test), Q value = 1

Table S982. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
CCDC96 MUTATED	0	1	1	2	0
CCDC96 WILD-TYPE	32	22	14	8	9

'CCDC96 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.592 (Chi-square test), Q value = 1

Table S983. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
CCDC96 MUTATED	0	0	2	1	1
CCDC96 WILD-TYPE	18	11	19	17	10

'CCDC96 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S984. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
CCDC96 MUTATED	1	1	1	1
CCDC96 WILD-TYPE	23	13	16	22

'CCDC96 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S985. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
CCDC96 MUTATED	1	1	2
CCDC96 WILD-TYPE	22	32	20

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S986. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
CCDC96 MUTATED	2	1	1
CCDC96 WILD-TYPE	35	15	25

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S987. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
CCDC96 MUTATED	1	0	3
CCDC96 WILD-TYPE	25	10	40

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S988. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
CCDC96 MUTATED	2	1	1
CCDC96 WILD-TYPE	36	17	22

'CCDC96 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S989. Gene #128: 'CCDC96 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
CCDC96 MUTATED	3	0	1
CCDC96 WILD-TYPE	38	11	26

'PCMTD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.257 (Chi-square test), Q value = 1

Table S990. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PCMTD1 MUTATED	0	2	0	1	0
PCMTD1 WILD-TYPE	32	21	15	9	9

'PCMTD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.21 (Chi-square test), Q value = 1

Table S991. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PCMTD1 MUTATED	0	0	3	1	0
PCMTD1 WILD-TYPE	18	11	18	17	11

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S992. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PCMTD1 MUTATED	0	1	2	1
PCMTD1 WILD-TYPE	24	13	15	22

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S993. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PCMTD1 MUTATED	0	2	2
PCMTD1 WILD-TYPE	23	31	20

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S994. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PCMTD1 MUTATED	2	1	1
PCMTD1 WILD-TYPE	35	15	25

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S995. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PCMTD1 MUTATED	2	0	2
PCMTD1 WILD-TYPE	24	10	41

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S996. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PCMTD1 MUTATED	2	1	1
PCMTD1 WILD-TYPE	36	17	22

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S997. Gene #129: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PCMTD1 MUTATED	2	0	2
PCMTD1 WILD-TYPE	39	11	25

'GLI3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.731 (Chi-square test), Q value = 1

Table S998. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GLI3 MUTATED	4	2	0	1	1
GLI3 WILD-TYPE	28	21	15	9	8

'GLI3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.217 (Chi-square test), Q value = 1

Table S999. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GLI3 MUTATED	2	0	0	3	2
GLI3 WILD-TYPE	16	11	21	15	9

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S1000. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GLI3 MUTATED	2	0	2	3
GLI3 WILD-TYPE	22	14	15	20

'GLI3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S1001. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GLI3 MUTATED	2	5	0
GLI3 WILD-TYPE	21	28	22

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S1002. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GLI3 MUTATED	5	0	2
GLI3 WILD-TYPE	32	16	24

'GLI3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S1003. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GLI3 MUTATED	2	0	5
GLI3 WILD-TYPE	24	10	38

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S1004. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GLI3 MUTATED	5	1	1
GLI3 WILD-TYPE	33	17	22

'GLI3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1005. Gene #130: 'GLI3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GLI3 MUTATED	4	1	2
GLI3 WILD-TYPE	37	10	25

'MN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.767 (Chi-square test), Q value = 1

Table S1006. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MN1 MUTATED	2	2	2	2	1
MN1 WILD-TYPE	30	21	13	8	8

'MN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.264 (Chi-square test), Q value = 1

Table S1007. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MN1 MUTATED	2	0	2	1	3
MN1 WILD-TYPE	16	11	19	17	8

'MN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S1008. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MN1 MUTATED	3	1	1	3
MN1 WILD-TYPE	21	13	16	20

'MN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S1009. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MN1 MUTATED	3	3	2
MN1 WILD-TYPE	20	30	20

'MN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S1010. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MN1 MUTATED	5	0	3
MN1 WILD-TYPE	32	16	23

'MN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S1011. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MN1 MUTATED	1	2	5
MN1 WILD-TYPE	25	8	38

'MN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S1012. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MN1 MUTATED	5	0	3
MN1 WILD-TYPE	33	18	20

'MN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.281 (Fisher's exact test), Q value = 1

Table S1013. Gene #131: 'MN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MN1 MUTATED	5	2	1
MN1 WILD-TYPE	36	9	26

'C9ORF66 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.51 (Chi-square test), Q value = 1

Table S1014. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
C9ORF66 MUTATED	1	3	2	1	0
C9ORF66 WILD-TYPE	31	20	13	9	9

'C9ORF66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.947 (Chi-square test), Q value = 1

Table S1015. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
C9ORF66 MUTATED	1	1	1	2	1
C9ORF66 WILD-TYPE	17	10	20	16	10

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1016. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
C9ORF66 MUTATED	2	2	1	1
C9ORF66 WILD-TYPE	22	12	16	22

'C9ORF66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S1017. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
C9ORF66 MUTATED	1	2	3
C9ORF66 WILD-TYPE	22	31	19

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S1018. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
C9ORF66 MUTATED	3	2	1
C9ORF66 WILD-TYPE	34	14	25

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1019. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
C9ORF66 MUTATED	2	0	4
C9ORF66 WILD-TYPE	24	10	39

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1020. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
C9ORF66 MUTATED	3	2	1
C9ORF66 WILD-TYPE	35	16	22

'C9ORF66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S1021. Gene #132: 'C9ORF66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
C9ORF66 MUTATED	3	0	3
C9ORF66 WILD-TYPE	38	11	24

'MADCAM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0541 (Chi-square test), Q value = 1

Table S1022. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
MADCAM1 MUTATED	0	2	3	0	0
MADCAM1 WILD-TYPE	32	21	12	10	9

'MADCAM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.864 (Chi-square test), Q value = 1

Table S1023. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
MADCAM1 MUTATED	1	0	2	1	1
MADCAM1 WILD-TYPE	17	11	19	17	10

'MADCAM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S1024. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
MADCAM1 MUTATED	0	1	2	1
MADCAM1 WILD-TYPE	24	13	15	22

'MADCAM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S1025. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
MADCAM1 MUTATED	0	2	2
MADCAM1 WILD-TYPE	23	31	20

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S1026. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
MADCAM1 MUTATED	4	0	1
MADCAM1 WILD-TYPE	33	16	25

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S1027. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
MADCAM1 MUTATED	0	1	4
MADCAM1 WILD-TYPE	26	9	39

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S1028. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
MADCAM1 MUTATED	4	0	1
MADCAM1 WILD-TYPE	34	18	22

'MADCAM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S1029. Gene #133: 'MADCAM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
MADCAM1 MUTATED	4	1	0
MADCAM1 WILD-TYPE	37	10	27

'BMP8A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.387 (Chi-square test), Q value = 1

Table S1030. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
BMP8A MUTATED	2	0	0	0	1
BMP8A WILD-TYPE	30	23	15	10	8

'BMP8A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S1031. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
BMP8A MUTATED	1	0	0	1	1
BMP8A WILD-TYPE	17	11	21	17	10

'BMP8A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1032. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
BMP8A MUTATED	1	0	1	1
BMP8A WILD-TYPE	23	14	16	22

'BMP8A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1033. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
BMP8A MUTATED	1	2	0
BMP8A WILD-TYPE	22	31	22

'BMP8A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1034. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
BMP8A MUTATED	2	0	1
BMP8A WILD-TYPE	35	16	25

'BMP8A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1035. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
BMP8A MUTATED	1	0	2
BMP8A WILD-TYPE	25	10	41

'BMP8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S1036. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
BMP8A MUTATED	2	1	0
BMP8A WILD-TYPE	36	17	23

'BMP8A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S1037. Gene #134: 'BMP8A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
BMP8A MUTATED	1	1	1
BMP8A WILD-TYPE	40	10	26

'ODF3L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S1038. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ODF3L2 MUTATED	1	1	1	0	0
ODF3L2 WILD-TYPE	31	22	14	10	9

'ODF3L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.661 (Chi-square test), Q value = 1

Table S1039. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ODF3L2 MUTATED	1	0	0	1	1
ODF3L2 WILD-TYPE	17	11	21	17	10

'ODF3L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S1040. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ODF3L2 MUTATED	2	0	0	1
ODF3L2 WILD-TYPE	22	14	17	22

'ODF3L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1041. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ODF3L2 MUTATED	1	2	0
ODF3L2 WILD-TYPE	22	31	22

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1042. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ODF3L2 MUTATED	1	1	1
ODF3L2 WILD-TYPE	36	15	25

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1043. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ODF3L2 MUTATED	2	0	1
ODF3L2 WILD-TYPE	24	10	42

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1044. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ODF3L2 MUTATED	1	1	1
ODF3L2 WILD-TYPE	37	17	22

'ODF3L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1045. Gene #135: 'ODF3L2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ODF3L2 MUTATED	1	0	2
ODF3L2 WILD-TYPE	40	11	25

'QRICH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Chi-square test), Q value = 1

Table S1046. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
QRICH2 MUTATED	2	1	0	1	0
QRICH2 WILD-TYPE	30	22	15	9	9

'QRICH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.635 (Chi-square test), Q value = 1

Table S1047. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
QRICH2 MUTATED	2	0	1	1	0
QRICH2 WILD-TYPE	16	11	20	17	11

'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S1048. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
QRICH2 MUTATED	2	0	2	0
QRICH2 WILD-TYPE	22	14	15	23

'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S1049. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
QRICH2 MUTATED	2	2	0
QRICH2 WILD-TYPE	21	31	22

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S1050. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
QRICH2 MUTATED	2	0	2
QRICH2 WILD-TYPE	35	16	24

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S1051. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
QRICH2 MUTATED	1	1	2
QRICH2 WILD-TYPE	25	9	41

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S1052. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
QRICH2 MUTATED	2	0	2
QRICH2 WILD-TYPE	36	18	21

'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S1053. Gene #136: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
QRICH2 MUTATED	2	1	1
QRICH2 WILD-TYPE	39	10	26

'KRTAP10-7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S1054. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KRTAP10-7 MUTATED	2	2	0	1	0
KRTAP10-7 WILD-TYPE	30	21	15	9	9

'KRTAP10-7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.359 (Chi-square test), Q value = 1

Table S1055. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
KRTAP10-7 MUTATED	0	1	3	1	0
KRTAP10-7 WILD-TYPE	18	10	18	17	11

'KRTAP10-7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S1056. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
KRTAP10-7 MUTATED	1	1	2	1
KRTAP10-7 WILD-TYPE	23	13	15	22

'KRTAP10-7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1057. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
KRTAP10-7 MUTATED	1	2	2
KRTAP10-7 WILD-TYPE	22	31	20

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0163 (Fisher's exact test), Q value = 1

Table S1058. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
KRTAP10-7 MUTATED	0	3	2
KRTAP10-7 WILD-TYPE	37	13	24

Figure S67. Get High-res Image Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S1059. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
KRTAP10-7 MUTATED	1	2	2
KRTAP10-7 WILD-TYPE	25	8	41

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0264 (Fisher's exact test), Q value = 1

Table S1060. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
KRTAP10-7 MUTATED	0	3	2
KRTAP10-7 WILD-TYPE	38	15	21

Figure S68. Get High-res Image Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'KRTAP10-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S1061. Gene #137: 'KRTAP10-7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
KRTAP10-7 MUTATED	2	2	1
KRTAP10-7 WILD-TYPE	39	9	26

'IDI1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Chi-square test), Q value = 1

Table S1062. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IDI1 MUTATED	2	1	2	0	0
IDI1 WILD-TYPE	30	22	13	10	9

'IDI1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.564 (Chi-square test), Q value = 1

Table S1063. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
IDI1 MUTATED	2	0	1	2	0
IDI1 WILD-TYPE	16	11	20	16	11

'IDI1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S1064. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
IDI1 MUTATED	1	2	1	1
IDI1 WILD-TYPE	23	12	16	22

'IDI1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1065. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
IDI1 MUTATED	1	2	2
IDI1 WILD-TYPE	22	31	20

'IDI1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1066. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
IDI1 MUTATED	2	1	2
IDI1 WILD-TYPE	35	15	24

'IDI1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S1067. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
IDI1 MUTATED	3	0	2
IDI1 WILD-TYPE	23	10	41

'IDI1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S1068. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
IDI1 MUTATED	2	1	2
IDI1 WILD-TYPE	36	17	21

'IDI1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S1069. Gene #138: 'IDI1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
IDI1 MUTATED	2	0	3
IDI1 WILD-TYPE	39	11	24

'IER5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.237 (Chi-square test), Q value = 1

Table S1070. Gene #139: 'IER5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
IER5 MUTATED	3	0	0	0	0
IER5 WILD-TYPE	29	23	15	10	9

'PRR21 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.585 (Chi-square test), Q value = 1

Table S1071. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PRR21 MUTATED	2	3	1	0	0
PRR21 WILD-TYPE	30	20	14	10	9

'PRR21 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.684 (Chi-square test), Q value = 1

Table S1072. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PRR21 MUTATED	0	1	1	2	1
PRR21 WILD-TYPE	18	10	20	16	10

'PRR21 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S1073. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PRR21 MUTATED	2	1	0	2
PRR21 WILD-TYPE	22	13	17	21

'PRR21 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S1074. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PRR21 MUTATED	1	3	1
PRR21 WILD-TYPE	22	30	21

'PRR21 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1075. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	35	15	24

'PRR21 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1076. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	24	9	41

'PRR21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S1077. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	36	17	21

'PRR21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S1078. Gene #140: 'PRR21 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PRR21 MUTATED	2	1	2
PRR21 WILD-TYPE	39	10	25

'ARRDC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.465 (Chi-square test), Q value = 1

Table S1079. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
ARRDC4 MUTATED	4	1	2	0	0
ARRDC4 WILD-TYPE	28	22	13	10	9

'ARRDC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.334 (Chi-square test), Q value = 1

Table S1080. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
ARRDC4 MUTATED	2	2	2	0	0
ARRDC4 WILD-TYPE	16	9	19	18	11

'ARRDC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S1081. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
ARRDC4 MUTATED	3	1	2	0
ARRDC4 WILD-TYPE	21	13	15	23

'ARRDC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S1082. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
ARRDC4 MUTATED	4	1	1
ARRDC4 WILD-TYPE	19	32	21

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S1083. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
ARRDC4 MUTATED	3	2	1
ARRDC4 WILD-TYPE	34	14	25

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S1084. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
ARRDC4 MUTATED	1	1	4
ARRDC4 WILD-TYPE	25	9	39

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1085. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
ARRDC4 MUTATED	3	2	1
ARRDC4 WILD-TYPE	35	16	22

'ARRDC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S1086. Gene #141: 'ARRDC4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
ARRDC4 MUTATED	4	1	1
ARRDC4 WILD-TYPE	37	10	26

'RNF135 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.709 (Chi-square test), Q value = 1

Table S1087. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RNF135 MUTATED	1	2	1	0	0
RNF135 WILD-TYPE	31	21	14	10	9

'RNF135 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.344 (Chi-square test), Q value = 1

Table S1088. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RNF135 MUTATED	1	0	0	2	0
RNF135 WILD-TYPE	17	11	21	16	11

'RNF135 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S1089. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RNF135 MUTATED	0	1	0	2
RNF135 WILD-TYPE	24	13	17	21

'RNF135 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S1090. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RNF135 MUTATED	0	2	1
RNF135 WILD-TYPE	23	31	21

'RNF135 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1091. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RNF135 MUTATED	1	1	1
RNF135 WILD-TYPE	36	15	25

'RNF135 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1092. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RNF135 MUTATED	2	0	1
RNF135 WILD-TYPE	24	10	42

'RNF135 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1093. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RNF135 MUTATED	1	1	1
RNF135 WILD-TYPE	37	17	22

'RNF135 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1094. Gene #142: 'RNF135 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RNF135 MUTATED	1	0	2
RNF135 WILD-TYPE	40	11	25

'DAXX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0325 (Chi-square test), Q value = 1

Table S1095. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DAXX MUTATED	1	0	3	0	0
DAXX WILD-TYPE	31	23	12	10	9

Figure S69. Get High-res Image Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'DAXX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.21 (Chi-square test), Q value = 1

Table S1096. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DAXX MUTATED	1	0	3	0	0
DAXX WILD-TYPE	17	11	18	18	11

'DAXX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S1097. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DAXX MUTATED	1	2	1	0
DAXX WILD-TYPE	23	12	16	23

'DAXX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S1098. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DAXX MUTATED	1	0	3
DAXX WILD-TYPE	22	33	19

Figure S70. Get High-res Image Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'DAXX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 1

Table S1099. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DAXX MUTATED	3	1	0
DAXX WILD-TYPE	34	15	26

'DAXX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1100. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DAXX MUTATED	1	0	3
DAXX WILD-TYPE	25	10	40

'DAXX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S1101. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DAXX MUTATED	3	1	0
DAXX WILD-TYPE	35	17	23

'DAXX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1102. Gene #143: 'DAXX MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DAXX MUTATED	3	0	1
DAXX WILD-TYPE	38	11	26

'VARS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.749 (Chi-square test), Q value = 1

Table S1103. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
VARS MUTATED	2	2	1	2	1
VARS WILD-TYPE	30	21	14	8	8

'VARS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.931 (Chi-square test), Q value = 1

Table S1104. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
VARS MUTATED	1	1	3	2	1
VARS WILD-TYPE	17	10	18	16	10

'VARS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S1105. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
VARS MUTATED	2	0	4	2
VARS WILD-TYPE	22	14	13	21

'VARS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S1106. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
VARS MUTATED	1	3	4
VARS WILD-TYPE	22	30	18

'VARS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S1107. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
VARS MUTATED	2	3	3
VARS WILD-TYPE	35	13	23

'VARS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1108. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
VARS MUTATED	3	1	4
VARS WILD-TYPE	23	9	39

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 1

Table S1109. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
VARS MUTATED	2	4	2
VARS WILD-TYPE	36	14	21

'VARS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S1110. Gene #144: 'VARS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
VARS MUTATED	3	1	4
VARS WILD-TYPE	38	10	23

'GPR20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Chi-square test), Q value = 1

Table S1111. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
GPR20 MUTATED	2	0	1	1	0
GPR20 WILD-TYPE	30	23	14	9	9

'GPR20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S1112. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
GPR20 MUTATED	1	0	1	0	1
GPR20 WILD-TYPE	17	11	20	18	10

'GPR20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S1113. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
GPR20 MUTATED	1	0	2	0
GPR20 WILD-TYPE	23	14	15	23

'GPR20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1114. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
GPR20 MUTATED	1	1	1
GPR20 WILD-TYPE	22	32	21

'GPR20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S1115. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
GPR20 MUTATED	2	1	0
GPR20 WILD-TYPE	35	15	26

'GPR20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1116. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
GPR20 MUTATED	1	0	2
GPR20 WILD-TYPE	25	10	41

'GPR20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S1117. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
GPR20 MUTATED	2	1	0
GPR20 WILD-TYPE	36	17	23

'GPR20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1118. Gene #145: 'GPR20 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
GPR20 MUTATED	2	0	1
GPR20 WILD-TYPE	39	11	26

'SAMD11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.433 (Chi-square test), Q value = 1

Table S1119. Gene #146: 'SAMD11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
SAMD11 MUTATED	2	0	0	1	0
SAMD11 WILD-TYPE	30	23	15	9	9

'DMWD MUTATION STATUS' versus 'CN_CNMF'

P value = 0.254 (Chi-square test), Q value = 1

Table S1120. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
DMWD MUTATED	1	0	2	0	1
DMWD WILD-TYPE	31	23	13	10	8

'DMWD MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.788 (Chi-square test), Q value = 1

Table S1121. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
DMWD MUTATED	1	1	1	0	1
DMWD WILD-TYPE	17	10	20	18	10

'DMWD MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1122. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
DMWD MUTATED	1	1	2	0
DMWD WILD-TYPE	23	13	15	23

'DMWD MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S1123. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
DMWD MUTATED	2	1	1
DMWD WILD-TYPE	21	32	21

'DMWD MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1124. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
DMWD MUTATED	2	1	1
DMWD WILD-TYPE	35	15	25

'DMWD MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1125. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
DMWD MUTATED	1	0	3
DMWD WILD-TYPE	25	10	40

'DMWD MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S1126. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
DMWD MUTATED	2	2	0
DMWD WILD-TYPE	36	16	23

'DMWD MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1127. Gene #147: 'DMWD MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
DMWD MUTATED	3	0	1
DMWD WILD-TYPE	38	11	26

'KISS1R MUTATION STATUS' versus 'CN_CNMF'

P value = 0.872 (Chi-square test), Q value = 1

Table S1128. Gene #148: 'KISS1R MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
KISS1R MUTATED	1	1	1	0	0
KISS1R WILD-TYPE	31	22	14	10	9

'PLEC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Chi-square test), Q value = 1

Table S1129. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
PLEC MUTATED	6	7	2	1	1
PLEC WILD-TYPE	26	16	13	9	8

'PLEC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.75 (Chi-square test), Q value = 1

Table S1130. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
PLEC MUTATED	4	3	2	3	2
PLEC WILD-TYPE	14	8	19	15	9

'PLEC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S1131. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
PLEC MUTATED	3	1	6	4
PLEC WILD-TYPE	21	13	11	19

'PLEC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S1132. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
PLEC MUTATED	3	7	4
PLEC WILD-TYPE	20	26	18

'PLEC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S1133. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
PLEC MUTATED	6	4	4
PLEC WILD-TYPE	31	12	22

'PLEC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1134. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
PLEC MUTATED	4	3	7
PLEC WILD-TYPE	22	7	36

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1135. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
PLEC MUTATED	7	3	4
PLEC WILD-TYPE	31	15	19

'PLEC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1136. Gene #149: 'PLEC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
PLEC MUTATED	7	3	4
PLEC WILD-TYPE	34	8	23

'FAM110C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.723 (Chi-square test), Q value = 1

Table S1137. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
FAM110C MUTATED	2	1	0	0	0
FAM110C WILD-TYPE	30	22	15	10	9

'FAM110C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.7 (Chi-square test), Q value = 1

Table S1138. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
FAM110C MUTATED	1	1	1	0	0
FAM110C WILD-TYPE	17	10	20	18	11

'FAM110C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S1139. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
FAM110C MUTATED	2	0	1	0
FAM110C WILD-TYPE	22	14	16	23

'FAM110C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S1140. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
FAM110C MUTATED	2	1	0
FAM110C WILD-TYPE	21	32	22

'FAM110C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1141. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
FAM110C MUTATED	2	0	1
FAM110C WILD-TYPE	35	16	25

'FAM110C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S1142. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
FAM110C MUTATED	0	1	2
FAM110C WILD-TYPE	26	9	41

'FAM110C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1143. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
FAM110C MUTATED	2	0	1
FAM110C WILD-TYPE	36	18	22

'FAM110C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 1

Table S1144. Gene #150: 'FAM110C MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
FAM110C MUTATED	2	1	0
FAM110C WILD-TYPE	39	10	27

'RCCD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.694 (Chi-square test), Q value = 1

Table S1145. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	32	23	15	10	9
RCCD1 MUTATED	2	2	0	1	0
RCCD1 WILD-TYPE	30	21	15	9	9

'RCCD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.371 (Chi-square test), Q value = 1

Table S1146. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	18	11	21	18	11
RCCD1 MUTATED	0	0	1	2	0
RCCD1 WILD-TYPE	18	11	20	16	11

'RCCD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1147. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	24	14	17	23
RCCD1 MUTATED	0	0	1	2
RCCD1 WILD-TYPE	24	14	16	21

'RCCD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S1148. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	23	33	22
RCCD1 MUTATED	0	2	1
RCCD1 WILD-TYPE	23	31	21

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1149. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	37	16	26
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	36	15	25

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1150. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	26	10	43
RCCD1 MUTATED	1	0	2
RCCD1 WILD-TYPE	25	10	41

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S1151. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	38	18	23
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	37	17	22

'RCCD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S1152. Gene #151: 'RCCD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	41	11	27
RCCD1 MUTATED	1	1	1
RCCD1 WILD-TYPE	40	10	26

Methods & Data

Input

Mutation data file = transformed.cor.cli.txt
Molecular subtypes file = ACC-TP.transferedmergedcluster.txt
Number of patients = 91
Number of significantly mutated genes = 151
Number of Molecular subtypes = 8
Exclude genes that fewer than K tumors have mutations, K = 3

Chi-square test

For multi-class clinical features (nominal or ordinal), Chi-square tests (Greenwood and Nikulin 1996) were used to estimate the P values using the 'chisq.test' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Greenwood and Nikulin, A guide to chi-squared testing, Wiley, New York. ISBN 047155779X (1996)

[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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