Correlation between gene mutation status and molecular subtypes
Liver Hepatocellular Carcinoma (Primary solid tumor)
15 July 2014  |  analyses__2014_07_15
Maintainer Information
Citation Information
doi:10.7908/C1X9292X
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1X9292X
Overview
Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 101 genes and 8 molecular subtypes across 202 patients, 8 significant findings detected with P value < 0.05 and Q value < 0.25.

  • TP53 mutation correlated to 'MRNASEQ_CNMF' and 'MIRSEQ_CHIERARCHICAL'.

  • CTNNB1 mutation correlated to 'METHLYATION_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • BAP1 mutation correlated to 'MRNASEQ_CNMF'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between mutation status of 101 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 8 significant findings detected.

Clinical
Features 		CN
CNMF 		METHLYATION
CNMF 		MRNASEQ
CNMF 		MRNASEQ
CHIERARCHICAL 		MIRSEQ
CNMF 		MIRSEQ
CHIERARCHICAL 		MIRSEQ
MATURE
CNMF 		MIRSEQ
MATURE
CHIERARCHICAL
nMutated (%) nWild-Type Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
CTNNB1 57 (28%) 145 0.00228
(1.00) 		0.00017
(0.136) 		1e-05
(0.00806) 		1e-05
(0.00806) 		0.218
(1.00) 		1e-05
(0.00806) 		0.00059
(0.471) 		1e-05
(0.00806)
TP53 65 (32%) 137 0.058
(1.00) 		0.451
(1.00) 		0.00025
(0.2) 		0.979
(1.00) 		0.00898
(1.00) 		1e-05
(0.00806) 		0.0296
(1.00) 		0.00238
(1.00)
BAP1 11 (5%) 191 0.732
(1.00) 		0.00168
(1.00) 		5e-05
(0.04) 		0.00095
(0.757) 		0.0212
(1.00) 		0.00099
(0.788) 		0.00323
(1.00) 		0.0332
(1.00)
ARID1A 25 (12%) 177 0.729
(1.00) 		0.891
(1.00) 		0.191
(1.00) 		0.41
(1.00) 		0.353
(1.00) 		0.0213
(1.00) 		0.452
(1.00) 		0.511
(1.00)
RB1 18 (9%) 184 0.0217
(1.00) 		0.00224
(1.00) 		0.0394
(1.00) 		0.0339
(1.00) 		0.34
(1.00) 		0.522
(1.00) 		0.0865
(1.00) 		0.311
(1.00)
AXIN1 12 (6%) 190 0.067
(1.00) 		0.692
(1.00) 		0.132
(1.00) 		0.0669
(1.00) 		0.144
(1.00) 		0.0475
(1.00) 		0.0116
(1.00) 		0.0764
(1.00)
KRTAP5-11 5 (2%) 197 0.534
(1.00) 		0.859
(1.00) 		0.489
(1.00) 		0.843
(1.00) 		0.451
(1.00) 		0.884
(1.00) 		0.657
(1.00) 		0.791
(1.00)
AHCTF1 13 (6%) 189 0.875
(1.00) 		0.614
(1.00) 		0.77
(1.00) 		0.329
(1.00) 		0.578
(1.00) 		0.102
(1.00) 		0.779
(1.00) 		0.558
(1.00)
GPATCH4 11 (5%) 191 0.0405
(1.00) 		0.855
(1.00) 		0.585
(1.00) 		0.635
(1.00) 		0.177
(1.00) 		0.122
(1.00) 		0.0436
(1.00) 		0.0617
(1.00)
CD207 8 (4%) 194 0.305
(1.00) 		0.185
(1.00) 		0.432
(1.00) 		0.691
(1.00) 		0.529
(1.00) 		0.568
(1.00) 		0.82
(1.00) 		0.557
(1.00)
EEF1A1 9 (4%) 193 1
(1.00) 		0.377
(1.00) 		0.173
(1.00) 		0.0256
(1.00) 		0.754
(1.00) 		0.589
(1.00) 		0.551
(1.00) 		0.606
(1.00)
CHIT1 8 (4%) 194 0.42
(1.00) 		1
(1.00) 		0.721
(1.00) 		0.715
(1.00) 		0.468
(1.00) 		0.418
(1.00) 		0.503
(1.00) 		0.85
(1.00)
PPIAL4G 7 (3%) 195 0.794
(1.00) 		0.324
(1.00) 		0.283
(1.00) 		0.269
(1.00) 		0.228
(1.00) 		0.123
(1.00) 		0.165
(1.00) 		0.111
(1.00)
ALB 24 (12%) 178 0.0362
(1.00) 		0.414
(1.00) 		0.621
(1.00) 		0.631
(1.00) 		0.881
(1.00) 		0.907
(1.00) 		0.327
(1.00) 		0.638
(1.00)
PABPC1 8 (4%) 194 0.274
(1.00) 		1
(1.00) 		0.322
(1.00) 		0.459
(1.00) 		0.668
(1.00) 		0.841
(1.00) 		0.933
(1.00) 		0.979
(1.00)
TREML2 6 (3%) 196 0.628
(1.00) 		1
(1.00) 		0.175
(1.00) 		0.0906
(1.00) 		0.449
(1.00) 		0.0316
(1.00) 		0.492
(1.00) 		0.0324
(1.00)
PRH2 6 (3%) 196 0.661
(1.00) 		0.874
(1.00) 		0.448
(1.00) 		0.866
(1.00) 		0.769
(1.00) 		0.859
(1.00) 		0.39
(1.00) 		0.971
(1.00)
MUC17 28 (14%) 174 0.865
(1.00) 		0.87
(1.00) 		0.663
(1.00) 		0.734
(1.00) 		0.635
(1.00) 		0.552
(1.00) 		0.84
(1.00) 		0.502
(1.00)
AZIN1 13 (6%) 189 0.318
(1.00) 		0.44
(1.00) 		0.0375
(1.00) 		0.388
(1.00) 		0.0276
(1.00) 		0.0152
(1.00) 		0.108
(1.00) 		0.00501
(1.00)
NBPF3 7 (3%) 195 0.267
(1.00) 		0.426
(1.00) 		0.0353
(1.00) 		0.864
(1.00) 		0.796
(1.00) 		0.587
(1.00) 		0.542
(1.00) 		0.825
(1.00)
BCLAF1 14 (7%) 188 0.829
(1.00) 		0.291
(1.00) 		0.679
(1.00) 		1
(1.00) 		0.883
(1.00) 		0.823
(1.00) 		0.535
(1.00) 		0.908
(1.00)
SCRN3 9 (4%) 193 0.346
(1.00) 		0.199
(1.00) 		0.731
(1.00) 		0.493
(1.00) 		0.688
(1.00) 		0.589
(1.00) 		0.33
(1.00) 		0.61
(1.00)
MUC6 25 (12%) 177 0.12
(1.00) 		0.0854
(1.00) 		0.532
(1.00) 		0.923
(1.00) 		0.588
(1.00) 		0.234
(1.00) 		0.436
(1.00) 		0.307
(1.00)
UGT2B28 11 (5%) 191 0.302
(1.00) 		0.225
(1.00) 		0.14
(1.00) 		0.13
(1.00) 		0.146
(1.00) 		0.142
(1.00) 		0.693
(1.00) 		0.293
(1.00)
CDHR5 11 (5%) 191 0.055
(1.00) 		0.111
(1.00) 		0.96
(1.00) 		0.664
(1.00) 		0.789
(1.00) 		0.805
(1.00) 		0.839
(1.00) 		0.89
(1.00)
KCTD3 6 (3%) 196 0.024
(1.00) 		0.376
(1.00) 		0.755
(1.00) 		0.657
(1.00) 		0.508
(1.00) 		0.383
(1.00) 		0.348
(1.00) 		0.309
(1.00)
CDC27 14 (7%) 188 0.534
(1.00) 		0.291
(1.00) 		0.054
(1.00) 		0.00473
(1.00) 		0.114
(1.00) 		0.0196
(1.00) 		0.119
(1.00) 		0.0577
(1.00)
CR1 19 (9%) 183 0.954
(1.00) 		0.861
(1.00) 		0.508
(1.00) 		0.442
(1.00) 		0.296
(1.00) 		0.316
(1.00) 		0.547
(1.00) 		0.758
(1.00)
TCEAL6 4 (2%) 198 0.0383
(1.00) 		0.154
(1.00) 		0.0622
(1.00) 		0.786
(1.00) 		0.553
(1.00) 		0.274
(1.00) 		1
(1.00) 		0.38
(1.00)
LILRA6 11 (5%) 191 0.232
(1.00) 		0.208
(1.00) 		0.35
(1.00) 		0.0781
(1.00) 		0.117
(1.00) 		0.00605
(1.00) 		0.162
(1.00) 		0.0374
(1.00)
BIK 3 (1%) 199 0.351
(1.00) 		0.795
(1.00) 		0.716
(1.00) 		1
(1.00) 		0.253
(1.00) 		0.108
(1.00) 		0.226
(1.00) 		0.03
(1.00)
SRRM3 4 (2%) 198 0.0384
(1.00) 		0.155
(1.00) 		0.132
(1.00) 		0.315
(1.00) 		0.085
(1.00) 		0.0222
(1.00) 		0.868
(1.00) 		0.0301
(1.00)
MKI67 17 (8%) 185 1
(1.00) 		0.466
(1.00) 		0.553
(1.00) 		0.431
(1.00) 		0.948
(1.00) 		0.349
(1.00) 		0.168
(1.00) 		0.666
(1.00)
ALDH3B1 5 (2%) 197 0.0117
(1.00) 		0.074
(1.00) 		0.345
(1.00) 		1
(1.00) 		0.741
(1.00) 		0.407
(1.00) 		1
(1.00) 		0.538
(1.00)
POTEG 13 (6%) 189 0.0931
(1.00) 		0.472
(1.00) 		0.834
(1.00) 		0.419
(1.00) 		0.617
(1.00) 		0.327
(1.00) 		0.148
(1.00) 		0.337
(1.00)
ZNF658 8 (4%) 194 0.0114
(1.00) 		0.238
(1.00) 		0.437
(1.00) 		0.233
(1.00) 		1
(1.00) 		0.142
(1.00) 		0.8
(1.00) 		0.302
(1.00)
TCHH 22 (11%) 180 0.514
(1.00) 		0.0424
(1.00) 		0.658
(1.00) 		0.608
(1.00) 		1
(1.00) 		0.106
(1.00) 		0.844
(1.00) 		0.323
(1.00)
TMEM176A 4 (2%) 198 0.174
(1.00) 		0.154
(1.00) 		0.239
(1.00) 		1
(1.00) 		0.134
(1.00) 		0.682
(1.00) 		0.257
(1.00) 		0.935
(1.00)
RP1L1 21 (10%) 181 0.341
(1.00) 		0.061
(1.00) 		0.0109
(1.00) 		0.544
(1.00) 		0.67
(1.00) 		0.799
(1.00) 		0.329
(1.00) 		0.301
(1.00)
TSC2 15 (7%) 187 0.316
(1.00) 		0.0452
(1.00) 		0.472
(1.00) 		0.499
(1.00) 		0.837
(1.00) 		0.578
(1.00) 		0.604
(1.00) 		0.74
(1.00)
PRKDC 24 (12%) 178 0.887
(1.00) 		0.164
(1.00) 		0.625
(1.00) 		0.918
(1.00) 		1
(1.00) 		0.17
(1.00) 		0.689
(1.00) 		0.367
(1.00)
NRD1 11 (5%) 191 0.422
(1.00) 		0.924
(1.00) 		0.887
(1.00) 		0.177
(1.00) 		0.791
(1.00) 		0.144
(1.00) 		0.563
(1.00) 		0.0804
(1.00)
TAS2R20 4 (2%) 198 0.301
(1.00) 		0.278
(1.00) 		0.487
(1.00) 		0.0106
(1.00) 		0.836
(1.00) 		0.0829
(1.00) 		0.667
(1.00) 		0.539
(1.00)
PTEN 10 (5%) 192 0.188
(1.00) 		0.0982
(1.00) 		0.86
(1.00) 		0.824
(1.00) 		0.46
(1.00) 		0.829
(1.00) 		0.934
(1.00) 		0.81
(1.00)
CYFIP2 13 (6%) 189 0.766
(1.00) 		0.714
(1.00) 		0.657
(1.00) 		0.331
(1.00) 		0.186
(1.00) 		0.887
(1.00) 		0.311
(1.00) 		0.606
(1.00)
PRAMEF1 9 (4%) 193 1
(1.00) 		0.507
(1.00) 		0.285
(1.00) 		0.145
(1.00) 		0.579
(1.00) 		0.0206
(1.00) 		0.0642
(1.00) 		0.203
(1.00)
MST1 8 (4%) 194 0.421
(1.00) 		0.584
(1.00) 		0.636
(1.00) 		0.777
(1.00) 		0.819
(1.00) 		0.652
(1.00) 		0.965
(1.00) 		0.946
(1.00)
ZC3H7A 12 (6%) 190 0.258
(1.00) 		0.744
(1.00) 		0.71
(1.00) 		0.856
(1.00) 		0.243
(1.00) 		0.792
(1.00) 		0.252
(1.00) 		0.128
(1.00)
MLL3 30 (15%) 172 0.438
(1.00) 		0.494
(1.00) 		0.0177
(1.00) 		0.481
(1.00) 		0.907
(1.00) 		0.564
(1.00) 		0.149
(1.00) 		0.925
(1.00)
HNRNPCL1 11 (5%) 191 0.162
(1.00) 		0.925
(1.00) 		0.546
(1.00) 		0.761
(1.00) 		0.193
(1.00) 		0.327
(1.00) 		0.732
(1.00) 		0.848
(1.00)
TUBA3E 7 (3%) 195 0.795
(1.00) 		0.889
(1.00) 		0.122
(1.00) 		0.0658
(1.00) 		0.698
(1.00) 		0.00747
(1.00) 		0.219
(1.00) 		0.115
(1.00)
MUC21 16 (8%) 186 0.66
(1.00) 		1
(1.00) 		0.875
(1.00) 		0.439
(1.00) 		0.945
(1.00) 		0.734
(1.00) 		0.61
(1.00) 		0.662
(1.00)
HPS4 5 (2%) 197 0.175
(1.00) 		0.0566
(1.00) 		0.261
(1.00) 		0.105
(1.00) 		0.451
(1.00) 		0.239
(1.00) 		0.929
(1.00) 		0.885
(1.00)
OR2T4 14 (7%) 188 0.0162
(1.00) 		0.0546
(1.00) 		0.0532
(1.00) 		0.0128
(1.00) 		0.608
(1.00) 		0.215
(1.00) 		0.624
(1.00) 		0.167
(1.00)
SPDYE1 4 (2%) 198 0.235
(1.00) 		0.367
(1.00) 		0.491
(1.00) 		0.144
(1.00) 		0.453
(1.00) 		0.0425
(1.00) 		0.727
(1.00) 		0.454
(1.00)
COG2 6 (3%) 196 0.289
(1.00) 		0.118
(1.00) 		0.551
(1.00) 		0.844
(1.00) 		0.0742
(1.00) 		0.302
(1.00) 		0.523
(1.00) 		0.357
(1.00)
SEC63 10 (5%) 192 0.0535
(1.00) 		0.0886
(1.00) 		0.219
(1.00) 		0.713
(1.00) 		0.55
(1.00) 		0.16
(1.00) 		0.906
(1.00) 		0.934
(1.00)
LILRA3 5 (2%) 197 0.234
(1.00) 		0.213
(1.00) 		0.0226
(1.00) 		0.00464
(1.00) 		0.452
(1.00) 		0.00899
(1.00) 		0.139
(1.00) 		0.189
(1.00)
CYP2A6 6 (3%) 196 1
(1.00) 		0.172
(1.00) 		0.838
(1.00) 		0.0741
(1.00) 		1
(1.00) 		0.678
(1.00) 		0.562
(1.00) 		0.512
(1.00)
ZC3H11A 6 (3%) 196 0.373
(1.00) 		0.324
(1.00) 		0.216
(1.00) 		0.296
(1.00) 		0.883
(1.00) 		0.239
(1.00) 		0.862
(1.00) 		0.186
(1.00)
LCE4A 10 (5%) 192 0.222
(1.00) 		0.549
(1.00) 		0.453
(1.00) 		1
(1.00) 		0.844
(1.00) 		0.672
(1.00) 		0.0521
(1.00) 		0.934
(1.00)
ATXN3 6 (3%) 196 0.138
(1.00) 		0.33
(1.00) 		0.873
(1.00) 		0.866
(1.00) 		0.445
(1.00) 		0.887
(1.00) 		0.205
(1.00) 		0.837
(1.00)
GTF2IRD2B 5 (2%) 197 0.0648
(1.00) 		0.0728
(1.00) 		0.133
(1.00) 		0.315
(1.00) 		0.296
(1.00) 		0.113
(1.00) 		0.962
(1.00) 		0.159
(1.00)
QRICH2 19 (9%) 183 0.295
(1.00) 		0.352
(1.00) 		0.199
(1.00) 		0.214
(1.00) 		0.532
(1.00) 		0.173
(1.00) 		0.111
(1.00) 		0.465
(1.00)
PLAU 6 (3%) 196 0.507
(1.00) 		0.665
(1.00) 		0.31
(1.00) 		1
(1.00) 		0.882
(1.00) 		0.764
(1.00) 		0.883
(1.00) 		0.915
(1.00)
MAPKAPK2 4 (2%) 198 0.454
(1.00) 		0.689
(1.00) 		0.803
(1.00) 		1
(1.00) 		0.454
(1.00) 		0.769
(1.00) 		0.83
(1.00) 		0.146
(1.00)
NAP1L1 6 (3%) 196 0.505
(1.00) 		1
(1.00) 		0.134
(1.00) 		0.672
(1.00) 		0.339
(1.00) 		0.859
(1.00) 		0.728
(1.00) 		0.56
(1.00)
FAM118A 4 (2%) 198 0.682
(1.00) 		0.817
(1.00) 		0.532
(1.00) 		0.675
(1.00) 		0.369
(1.00) 		0.599
(1.00) 		0.217
(1.00) 		1
(1.00)
SLC7A6OS 4 (2%) 198 1
(1.00) 		1
(1.00) 		0.0375
(1.00) 		0.41
(1.00) 		0.291
(1.00) 		0.725
(1.00) 		0.389
(1.00) 		0.573
(1.00)
NBPF10 12 (6%) 190 0.204
(1.00) 		0.745
(1.00) 		1
(1.00) 		1
(1.00) 		0.558
(1.00) 		0.505
(1.00) 		0.526
(1.00) 		0.764
(1.00)
ZXDC 6 (3%) 196 1
(1.00) 		0.205
(1.00) 		0.236
(1.00) 		0.422
(1.00) 		0.00862
(1.00) 		0.0371
(1.00) 		0.124
(1.00) 		0.0647
(1.00)
TAS2R30 8 (4%) 194 1
(1.00) 		0.898
(1.00) 		0.536
(1.00) 		0.898
(1.00) 		0.742
(1.00) 		1
(1.00) 		0.152
(1.00) 		0.978
(1.00)
KRTAP10-2 7 (3%) 195 0.38
(1.00) 		0.702
(1.00) 		0.317
(1.00) 		0.269
(1.00) 		0.897
(1.00) 		0.0013
(1.00) 		0.103
(1.00) 		0.139
(1.00)
PPA2 4 (2%) 198 0.684
(1.00) 		0.581
(1.00) 		0.801
(1.00) 		1
(1.00) 		1
(1.00) 		0.6
(1.00) 		0.284
(1.00) 		0.454
(1.00)
SEPT2 7 (3%) 195 0.265
(1.00) 		0.285
(1.00) 		0.503
(1.00) 		0.295
(1.00) 		0.698
(1.00) 		0.585
(1.00) 		0.816
(1.00) 		0.467
(1.00)
DRD3 5 (2%) 197 0.627
(1.00) 		0.0726
(1.00) 		0.0385
(1.00) 		0.531
(1.00) 		0.00703
(1.00) 		0.314
(1.00) 		0.134
(1.00) 		0.356
(1.00)
PSRC1 4 (2%) 198 0.562
(1.00) 		0.369
(1.00) 		0.0418
(1.00) 		0.682
(1.00) 		0.319
(1.00) 		0.935
(1.00)
KRTAP10-9 3 (1%) 199 0.472
(1.00) 		0.612
(1.00) 		0.349
(1.00) 		0.0915
(1.00) 		1
(1.00) 		0.0432
(1.00) 		0.431
(1.00) 		0.629
(1.00)
SPATA12 6 (3%) 196 0.878
(1.00) 		1
(1.00) 		0.855
(1.00) 		1
(1.00) 		0.658
(1.00) 		0.859
(1.00) 		0.845
(1.00) 		0.68
(1.00)
GPR112 15 (7%) 187 0.528
(1.00) 		0.451
(1.00) 		0.533
(1.00) 		0.477
(1.00) 		0.488
(1.00) 		0.393
(1.00) 		0.162
(1.00) 		0.181
(1.00)
CLTCL1 16 (8%) 186 0.355
(1.00) 		0.377
(1.00) 		0.709
(1.00) 		0.6
(1.00) 		0.745
(1.00) 		0.0843
(1.00) 		0.826
(1.00) 		0.291
(1.00)
OR2A14 5 (2%) 197 0.626
(1.00) 		0.215
(1.00) 		0.805
(1.00) 		1
(1.00) 		1
(1.00) 		0.363
(1.00) 		0.587
(1.00) 		0.536
(1.00)
OR4C16 7 (3%) 195 0.0925
(1.00) 		0.127
(1.00) 		0.0197
(1.00) 		0.0336
(1.00) 		0.896
(1.00) 		0.00339
(1.00) 		0.756
(1.00) 		0.0788
(1.00)
GBP1 8 (4%) 194 0.277
(1.00) 		0.73
(1.00) 		0.842
(1.00) 		0.369
(1.00) 		0.743
(1.00) 		0.477
(1.00) 		0.832
(1.00) 		0.61
(1.00)
OR6B3 5 (2%) 197 0.736
(1.00) 		0.859
(1.00) 		0.767
(1.00) 		0.418
(1.00) 		0.116
(1.00) 		0.205
(1.00) 		0.781
(1.00) 		0.0763
(1.00)
OR2T27 10 (5%) 192 0.773
(1.00) 		0.0109
(1.00) 		0.265
(1.00) 		0.545
(1.00) 		0.354
(1.00) 		0.162
(1.00) 		0.512
(1.00) 		0.231
(1.00)
RAET1E 5 (2%) 197 0.849
(1.00) 		0.323
(1.00) 		0.182
(1.00) 		0.0332
(1.00) 		0.743
(1.00) 		0.0187
(1.00) 		0.551
(1.00) 		0.204
(1.00)
SHROOM1 5 (2%) 197 0.629
(1.00) 		0.861
(1.00) 		1
(1.00) 		1
(1.00) 		1
(1.00) 		0.26
(1.00) 		0.899
(1.00) 		0.0773
(1.00)
OR52I2 6 (3%) 196 0.764
(1.00) 		1
(1.00) 		0.344
(1.00) 		0.164
(1.00) 		0.768
(1.00) 		0.048
(1.00) 		0.295
(1.00) 		0.339
(1.00)
OR13C2 4 (2%) 198 0.173
(1.00) 		0.203
(1.00) 		0.0849
(1.00) 		0.0706
(1.00) 		0.453
(1.00) 		0.136
(1.00) 		0.67
(1.00) 		0.138
(1.00)
LIPC 6 (3%) 196 0.879
(1.00) 		1
(1.00) 		0.119
(1.00) 		0.747
(1.00) 		0.243
(1.00) 		0.969
(1.00) 		0.33
(1.00) 		0.972
(1.00)
FAM22F 4 (2%) 198 0.173
(1.00) 		0.0114
(1.00) 		0.0342
(1.00) 		0.0413
(1.00) 		0.18
(1.00) 		0.825
(1.00) 		0.00101
(0.803) 		0.302
(1.00)
GLRX3 4 (2%) 198 0.299
(1.00) 		0.368
(1.00) 		0.114
(1.00) 		0.0213
(1.00) 		0.451
(1.00) 		0.00792
(1.00) 		0.286
(1.00) 		0.201
(1.00)
HOXA4 5 (2%) 197 0.851
(1.00) 		0.388
(1.00) 		0.931
(1.00) 		0.844
(1.00) 		0.293
(1.00) 		0.0847
(1.00) 		0.393
(1.00) 		0.206
(1.00)
DENND4B 9 (4%) 193 0.383
(1.00) 		0.198
(1.00) 		0.0519
(1.00) 		0.217
(1.00) 		0.375
(1.00) 		0.223
(1.00) 		0.476
(1.00) 		0.38
(1.00)
ESX1 6 (3%) 196 0.879
(1.00) 		0.664
(1.00) 		0.157
(1.00) 		0.196
(1.00) 		0.881
(1.00) 		0.256
(1.00) 		0.128
(1.00) 		0.135
(1.00)
SLFN12L 6 (3%) 196 1
(1.00) 		0.282
(1.00) 		0.433
(1.00) 		0.843
(1.00) 		0.883
(1.00) 		0.813
(1.00) 		0.456
(1.00) 		0.916
(1.00)
FKBP4 5 (2%) 197 0.534
(1.00) 		0.384
(1.00) 		0.345
(1.00) 		0.247
(1.00) 		0.847
(1.00) 		0.554
(1.00) 		0.279
(1.00) 		0.431
(1.00)
AQP7 9 (4%) 193 0.911
(1.00) 		0.0226
(1.00) 		0.163
(1.00) 		0.449
(1.00) 		0.169
(1.00) 		0.233
(1.00) 		0.606
(1.00) 		0.152
(1.00)
MAP4K5 10 (5%) 192 0.384
(1.00) 		0.919
(1.00) 		0.55
(1.00) 		1
(1.00) 		1
(1.00) 		0.373
(1.00) 		0.607
(1.00) 		0.634
(1.00)
BCL11A 7 (3%) 195 0.795
(1.00) 		0.483
(1.00) 		0.755
(1.00) 		0.0733
(1.00) 		0.00489
(1.00) 		0.189
(1.00) 		0.303
(1.00) 		0.134
(1.00)
'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.058 (Fisher's exact test), Q value = 1

Table S1.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TP53 MUTATED 16 19 29
TP53 WILD-TYPE 33 60 39
'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S2.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TP53 MUTATED 33 16 16
TP53 WILD-TYPE 58 45 34
'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00025 (Fisher's exact test), Q value = 0.2

Table S3.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TP53 MUTATED 7 21 16 8 11
TP53 WILD-TYPE 29 10 42 27 26

Figure S1.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S4.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TP53 MUTATED 23 28 12
TP53 WILD-TYPE 52 57 25
'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00898 (Fisher's exact test), Q value = 1

Table S5.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TP53 MUTATED 24 23 17
TP53 WILD-TYPE 24 53 56

Figure S2.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S6.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TP53 MUTATED 15 22 11 14 2
TP53 WILD-TYPE 9 31 62 12 19

Figure S3.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0296 (Fisher's exact test), Q value = 1

Table S7.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TP53 MUTATED 11 10 20 16 7
TP53 WILD-TYPE 15 24 20 44 30

Figure S4.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00238 (Fisher's exact test), Q value = 1

Table S8.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TP53 MUTATED 14 17 14 16 3
TP53 WILD-TYPE 9 29 21 55 19

Figure S5.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00228 (Fisher's exact test), Q value = 1

Table S9.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CTNNB1 MUTATED 24 19 14
CTNNB1 WILD-TYPE 25 60 54

Figure S6.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00017 (Fisher's exact test), Q value = 0.14

Table S10.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CTNNB1 MUTATED 39 10 8
CTNNB1 WILD-TYPE 52 51 42

Figure S7.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S11.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CTNNB1 MUTATED 5 5 10 4 33
CTNNB1 WILD-TYPE 31 26 48 31 4

Figure S8.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S12.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CTNNB1 MUTATED 8 16 33
CTNNB1 WILD-TYPE 67 69 4

Figure S9.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S13.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CTNNB1 MUTATED 12 27 17
CTNNB1 WILD-TYPE 36 49 56
'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S14.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CTNNB1 MUTATED 8 9 11 10 18
CTNNB1 WILD-TYPE 16 44 62 16 3

Figure S10.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00059 (Fisher's exact test), Q value = 0.47

Table S15.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CTNNB1 MUTATED 8 3 11 28 6
CTNNB1 WILD-TYPE 18 31 29 32 31

Figure S11.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S16.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CTNNB1 MUTATED 8 7 8 16 17
CTNNB1 WILD-TYPE 15 39 27 55 5

Figure S12.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S17.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ARID1A MUTATED 7 8 9
ARID1A WILD-TYPE 42 71 59
'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S18.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ARID1A MUTATED 12 8 5
ARID1A WILD-TYPE 79 53 45
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S19.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ARID1A MUTATED 1 4 6 6 7
ARID1A WILD-TYPE 35 27 52 29 30
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S20.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ARID1A MUTATED 8 9 7
ARID1A WILD-TYPE 67 76 30
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S21.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ARID1A MUTATED 9 9 7
ARID1A WILD-TYPE 39 67 66
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0213 (Fisher's exact test), Q value = 1

Table S22.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ARID1A MUTATED 5 5 5 8 2
ARID1A WILD-TYPE 19 48 68 18 19

Figure S13.  Get High-res Image Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S23.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ARID1A MUTATED 6 3 6 7 3
ARID1A WILD-TYPE 20 31 34 53 34
'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S24.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ARID1A MUTATED 5 5 6 7 2
ARID1A WILD-TYPE 18 41 29 64 20
'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0217 (Fisher's exact test), Q value = 1

Table S25.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RB1 MUTATED 1 5 11
RB1 WILD-TYPE 48 74 57

Figure S14.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00224 (Fisher's exact test), Q value = 1

Table S26.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RB1 MUTATED 5 12 1
RB1 WILD-TYPE 86 49 49

Figure S15.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0394 (Fisher's exact test), Q value = 1

Table S27.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RB1 MUTATED 2 3 6 7 0
RB1 WILD-TYPE 34 28 52 28 37

Figure S16.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0339 (Fisher's exact test), Q value = 1

Table S28.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RB1 MUTATED 12 5 1
RB1 WILD-TYPE 63 80 36

Figure S17.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S29.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RB1 MUTATED 2 9 6
RB1 WILD-TYPE 46 67 67
'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S30.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RB1 MUTATED 1 5 9 2 0
RB1 WILD-TYPE 23 48 64 24 21
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 1

Table S31.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RB1 MUTATED 2 4 1 3 7
RB1 WILD-TYPE 24 30 39 57 30
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S32.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RB1 MUTATED 1 3 3 10 0
RB1 WILD-TYPE 22 43 32 61 22
'AXIN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.067 (Fisher's exact test), Q value = 1

Table S33.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AXIN1 MUTATED 2 2 8
AXIN1 WILD-TYPE 47 77 60
'AXIN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S34.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AXIN1 MUTATED 5 5 2
AXIN1 WILD-TYPE 86 56 48
'AXIN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S35.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AXIN1 MUTATED 2 1 4 5 0
AXIN1 WILD-TYPE 34 30 54 30 37
'AXIN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0669 (Fisher's exact test), Q value = 1

Table S36.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AXIN1 MUTATED 8 4 0
AXIN1 WILD-TYPE 67 81 37
'AXIN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S37.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AXIN1 MUTATED 0 6 5
AXIN1 WILD-TYPE 48 70 68
'AXIN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0475 (Fisher's exact test), Q value = 1

Table S38.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AXIN1 MUTATED 1 0 7 3 0
AXIN1 WILD-TYPE 23 53 66 23 21

Figure S18.  Get High-res Image Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'AXIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0116 (Fisher's exact test), Q value = 1

Table S39.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AXIN1 MUTATED 4 0 0 6 1
AXIN1 WILD-TYPE 22 34 40 54 36

Figure S19.  Get High-res Image Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'AXIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0764 (Fisher's exact test), Q value = 1

Table S40.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AXIN1 MUTATED 1 0 5 4 1
AXIN1 WILD-TYPE 22 46 30 67 21
'KRTAP5-11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S41.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP5-11 MUTATED 1 1 3
KRTAP5-11 WILD-TYPE 48 78 65
'KRTAP5-11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S42.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP5-11 MUTATED 3 1 1
KRTAP5-11 WILD-TYPE 88 60 49
'KRTAP5-11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S43.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP5-11 MUTATED 1 1 3 0 0
KRTAP5-11 WILD-TYPE 35 30 55 35 37
'KRTAP5-11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S44.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP5-11 MUTATED 2 3 0
KRTAP5-11 WILD-TYPE 73 82 37
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S45.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP5-11 MUTATED 0 3 2
KRTAP5-11 WILD-TYPE 48 73 71
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S46.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP5-11 MUTATED 0 2 3 0 0
KRTAP5-11 WILD-TYPE 24 51 70 26 21
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S47.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP5-11 MUTATED 0 1 0 3 1
KRTAP5-11 WILD-TYPE 26 33 40 57 36
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S48.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP5-11 MUTATED 0 2 0 3 0
KRTAP5-11 WILD-TYPE 23 44 35 68 22
'AHCTF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S49.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AHCTF1 MUTATED 4 5 4
AHCTF1 WILD-TYPE 45 74 64
'AHCTF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S50.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AHCTF1 MUTATED 8 3 2
AHCTF1 WILD-TYPE 83 58 48
'AHCTF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S51.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AHCTF1 MUTATED 1 2 4 2 4
AHCTF1 WILD-TYPE 35 29 54 33 33
'AHCTF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S52.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AHCTF1 MUTATED 3 6 4
AHCTF1 WILD-TYPE 72 79 33
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S53.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AHCTF1 MUTATED 4 6 3
AHCTF1 WILD-TYPE 44 70 70
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S54.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AHCTF1 MUTATED 2 4 2 1 4
AHCTF1 WILD-TYPE 22 49 71 25 17
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S55.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AHCTF1 MUTATED 2 1 2 6 2
AHCTF1 WILD-TYPE 24 33 38 54 35
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S56.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AHCTF1 MUTATED 2 3 1 4 3
AHCTF1 WILD-TYPE 21 43 34 67 19
'GPATCH4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0405 (Fisher's exact test), Q value = 1

Table S57.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GPATCH4 MUTATED 3 1 7
GPATCH4 WILD-TYPE 46 78 61

Figure S20.  Get High-res Image Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'GPATCH4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S58.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GPATCH4 MUTATED 6 3 2
GPATCH4 WILD-TYPE 85 58 48
'GPATCH4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S59.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GPATCH4 MUTATED 3 3 2 1 1
GPATCH4 WILD-TYPE 33 28 56 34 36
'GPATCH4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S60.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GPATCH4 MUTATED 3 6 1
GPATCH4 WILD-TYPE 72 79 36
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S61.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GPATCH4 MUTATED 5 2 4
GPATCH4 WILD-TYPE 43 74 69
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S62.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GPATCH4 MUTATED 4 3 4 0 0
GPATCH4 WILD-TYPE 20 50 69 26 21
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0436 (Fisher's exact test), Q value = 1

Table S63.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GPATCH4 MUTATED 2 3 5 1 0
GPATCH4 WILD-TYPE 24 31 35 59 37

Figure S21.  Get High-res Image Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 1

Table S64.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GPATCH4 MUTATED 4 3 0 4 0
GPATCH4 WILD-TYPE 19 43 35 67 22
'CD207 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S65.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CD207 MUTATED 4 2 2
CD207 WILD-TYPE 45 77 66
'CD207 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S66.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CD207 MUTATED 6 2 0
CD207 WILD-TYPE 85 59 50
'CD207 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S67.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CD207 MUTATED 0 2 1 2 2
CD207 WILD-TYPE 36 29 57 33 35
'CD207 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S68.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CD207 MUTATED 3 2 2
CD207 WILD-TYPE 72 83 35
'CD207 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S69.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CD207 MUTATED 3 2 3
CD207 WILD-TYPE 45 74 70
'CD207 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S70.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CD207 MUTATED 1 1 3 1 2
CD207 WILD-TYPE 23 52 70 25 19
'CD207 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S71.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CD207 MUTATED 0 2 2 2 2
CD207 WILD-TYPE 26 32 38 58 35
'CD207 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S72.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CD207 MUTATED 1 1 2 2 2
CD207 WILD-TYPE 22 45 33 69 20
'EEF1A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S73.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
EEF1A1 MUTATED 2 4 3
EEF1A1 WILD-TYPE 47 75 65
'EEF1A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S74.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
EEF1A1 MUTATED 6 1 2
EEF1A1 WILD-TYPE 85 60 48
'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S75.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
EEF1A1 MUTATED 1 0 5 0 3
EEF1A1 WILD-TYPE 35 31 53 35 34
'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S76.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
EEF1A1 MUTATED 0 6 3
EEF1A1 WILD-TYPE 75 79 34

Figure S22.  Get High-res Image Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S77.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
EEF1A1 MUTATED 1 4 4
EEF1A1 WILD-TYPE 47 72 69
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S78.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
EEF1A1 MUTATED 1 3 3 0 2
EEF1A1 WILD-TYPE 23 50 70 26 19
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S79.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
EEF1A1 MUTATED 0 2 1 5 1
EEF1A1 WILD-TYPE 26 32 39 55 36
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S80.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
EEF1A1 MUTATED 1 3 1 2 2
EEF1A1 WILD-TYPE 22 43 34 69 20
'BAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S81.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BAP1 MUTATED 2 6 3
BAP1 WILD-TYPE 47 73 65
'BAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00168 (Fisher's exact test), Q value = 1

Table S82.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BAP1 MUTATED 0 7 4
BAP1 WILD-TYPE 91 54 46

Figure S23.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'BAP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.04

Table S83.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BAP1 MUTATED 7 0 0 4 0
BAP1 WILD-TYPE 29 31 58 31 37

Figure S24.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'BAP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00095 (Fisher's exact test), Q value = 0.76

Table S84.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BAP1 MUTATED 10 1 0
BAP1 WILD-TYPE 65 84 37

Figure S25.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S85.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BAP1 MUTATED 0 3 8
BAP1 WILD-TYPE 48 73 65

Figure S26.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00099 (Fisher's exact test), Q value = 0.79

Table S86.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BAP1 MUTATED 0 0 11 0 0
BAP1 WILD-TYPE 24 53 62 26 21

Figure S27.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00323 (Fisher's exact test), Q value = 1

Table S87.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BAP1 MUTATED 1 2 0 1 7
BAP1 WILD-TYPE 25 32 40 59 30

Figure S28.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0332 (Fisher's exact test), Q value = 1

Table S88.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BAP1 MUTATED 0 0 4 7 0
BAP1 WILD-TYPE 23 46 31 64 22

Figure S29.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CHIT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S89.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CHIT1 MUTATED 3 4 1
CHIT1 WILD-TYPE 46 75 67
'CHIT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S90.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CHIT1 MUTATED 4 2 2
CHIT1 WILD-TYPE 87 59 48
'CHIT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S91.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CHIT1 MUTATED 1 0 4 1 2
CHIT1 WILD-TYPE 35 31 54 34 35
'CHIT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S92.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CHIT1 MUTATED 2 4 2
CHIT1 WILD-TYPE 73 81 35
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S93.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CHIT1 MUTATED 1 5 2
CHIT1 WILD-TYPE 47 71 71
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S94.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CHIT1 MUTATED 0 3 3 0 2
CHIT1 WILD-TYPE 24 50 70 26 19
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S95.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CHIT1 MUTATED 1 2 0 4 1
CHIT1 WILD-TYPE 25 32 40 56 36
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S96.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CHIT1 MUTATED 0 3 1 3 1
CHIT1 WILD-TYPE 23 43 34 68 21
'PPIAL4G MUTATION STATUS' versus 'CN_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S97.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PPIAL4G MUTATED 2 2 3
PPIAL4G WILD-TYPE 47 77 65
'PPIAL4G MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S98.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PPIAL4G MUTATED 4 3 0
PPIAL4G WILD-TYPE 87 58 50
'PPIAL4G MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 1

Table S99.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PPIAL4G MUTATED 0 0 2 2 3
PPIAL4G WILD-TYPE 36 31 56 33 34
'PPIAL4G MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S100.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PPIAL4G MUTATED 2 2 3
PPIAL4G WILD-TYPE 73 83 34
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S101.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PPIAL4G MUTATED 1 5 1
PPIAL4G WILD-TYPE 47 71 72
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S102.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PPIAL4G MUTATED 0 2 2 0 3
PPIAL4G WILD-TYPE 24 51 71 26 18
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S103.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PPIAL4G MUTATED 1 0 0 5 1
PPIAL4G WILD-TYPE 25 34 40 55 36
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S104.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PPIAL4G MUTATED 0 2 1 1 3
PPIAL4G WILD-TYPE 23 44 34 70 19
'ALB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S105.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ALB MUTATED 11 7 5
ALB WILD-TYPE 38 72 63

Figure S30.  Get High-res Image Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ALB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S106.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ALB MUTATED 14 5 5
ALB WILD-TYPE 77 56 45
'ALB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S107.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ALB MUTATED 2 5 8 4 3
ALB WILD-TYPE 34 26 50 31 34
'ALB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S108.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ALB MUTATED 7 12 3
ALB WILD-TYPE 68 73 34
'ALB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S109.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ALB MUTATED 6 9 7
ALB WILD-TYPE 42 67 66
'ALB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S110.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ALB MUTATED 4 5 8 3 2
ALB WILD-TYPE 20 48 65 23 19
'ALB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S111.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ALB MUTATED 1 2 6 10 3
ALB WILD-TYPE 25 32 34 50 34
'ALB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S112.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ALB MUTATED 4 3 5 8 2
ALB WILD-TYPE 19 43 30 63 20
'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S113.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PABPC1 MUTATED 0 4 4
PABPC1 WILD-TYPE 49 75 64
'PABPC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S114.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PABPC1 MUTATED 4 2 2
PABPC1 WILD-TYPE 87 59 48
'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S115.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PABPC1 MUTATED 1 3 2 2 0
PABPC1 WILD-TYPE 35 28 56 33 37
'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S116.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PABPC1 MUTATED 5 2 1
PABPC1 WILD-TYPE 70 83 36
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S117.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PABPC1 MUTATED 2 2 4
PABPC1 WILD-TYPE 46 74 69
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S118.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PABPC1 MUTATED 1 2 3 2 0
PABPC1 WILD-TYPE 23 51 70 24 21
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S119.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PABPC1 MUTATED 1 2 1 3 1
PABPC1 WILD-TYPE 25 32 39 57 36
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S120.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PABPC1 MUTATED 1 2 2 3 0
PABPC1 WILD-TYPE 22 44 33 68 22
'TREML2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S121.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TREML2 MUTATED 2 1 2
TREML2 WILD-TYPE 47 78 66
'TREML2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S122.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TREML2 MUTATED 3 2 1
TREML2 WILD-TYPE 88 59 49
'TREML2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S123.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TREML2 MUTATED 0 0 4 0 2
TREML2 WILD-TYPE 36 31 54 35 35
'TREML2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0906 (Fisher's exact test), Q value = 1

Table S124.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TREML2 MUTATED 0 4 2
TREML2 WILD-TYPE 75 81 35
'TREML2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S125.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TREML2 MUTATED 0 3 3
TREML2 WILD-TYPE 48 73 70
'TREML2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0316 (Fisher's exact test), Q value = 1

Table S126.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TREML2 MUTATED 0 0 3 0 3
TREML2 WILD-TYPE 24 53 70 26 18

Figure S31.  Get High-res Image Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S127.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TREML2 MUTATED 0 2 0 3 1
TREML2 WILD-TYPE 26 32 40 57 36
'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0324 (Fisher's exact test), Q value = 1

Table S128.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TREML2 MUTATED 0 0 0 3 3
TREML2 WILD-TYPE 23 46 35 68 19

Figure S32.  Get High-res Image Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PRH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S129.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRH2 MUTATED 2 3 1
PRH2 WILD-TYPE 47 76 67
'PRH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S130.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRH2 MUTATED 2 2 2
PRH2 WILD-TYPE 89 59 48
'PRH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S131.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRH2 MUTATED 0 2 1 2 1
PRH2 WILD-TYPE 36 29 57 33 36
'PRH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S132.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRH2 MUTATED 3 2 1
PRH2 WILD-TYPE 72 83 36
'PRH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S133.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRH2 MUTATED 2 2 2
PRH2 WILD-TYPE 46 74 71
'PRH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S134.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRH2 MUTATED 1 2 2 0 1
PRH2 WILD-TYPE 23 51 71 26 20
'PRH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S135.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRH2 MUTATED 2 0 2 1 1
PRH2 WILD-TYPE 24 34 38 59 36
'PRH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S136.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRH2 MUTATED 1 2 1 2 0
PRH2 WILD-TYPE 22 44 34 69 22
'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S137.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC17 MUTATED 7 12 8
MUC17 WILD-TYPE 42 67 60
'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S138.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC17 MUTATED 12 8 8
MUC17 WILD-TYPE 79 53 42
'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S139.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC17 MUTATED 6 3 6 7 5
MUC17 WILD-TYPE 30 28 52 28 32
'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S140.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC17 MUTATED 11 10 6
MUC17 WILD-TYPE 64 75 31
'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S141.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC17 MUTATED 5 13 10
MUC17 WILD-TYPE 43 63 63
'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S142.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC17 MUTATED 4 6 11 2 5
MUC17 WILD-TYPE 20 47 62 24 16
'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S143.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC17 MUTATED 4 4 4 9 7
MUC17 WILD-TYPE 22 30 36 51 30
'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S144.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC17 MUTATED 3 5 7 8 5
MUC17 WILD-TYPE 20 41 28 63 17
'AZIN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.318 (Fisher's exact test), Q value = 1

Table S145.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AZIN1 MUTATED 1 7 5
AZIN1 WILD-TYPE 48 72 63
'AZIN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S146.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AZIN1 MUTATED 8 2 3
AZIN1 WILD-TYPE 83 59 47
'AZIN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0375 (Fisher's exact test), Q value = 1

Table S147.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AZIN1 MUTATED 1 5 6 0 1
AZIN1 WILD-TYPE 35 26 52 35 36

Figure S33.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'AZIN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S148.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AZIN1 MUTATED 4 8 1
AZIN1 WILD-TYPE 71 77 36
'AZIN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0276 (Fisher's exact test), Q value = 1

Table S149.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AZIN1 MUTATED 6 6 1
AZIN1 WILD-TYPE 42 70 72

Figure S34.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'AZIN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0152 (Fisher's exact test), Q value = 1

Table S150.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AZIN1 MUTATED 5 5 1 1 1
AZIN1 WILD-TYPE 19 48 72 25 20

Figure S35.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'AZIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S151.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AZIN1 MUTATED 0 1 6 5 1
AZIN1 WILD-TYPE 26 33 34 55 36
'AZIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00501 (Fisher's exact test), Q value = 1

Table S152.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AZIN1 MUTATED 4 5 3 0 1
AZIN1 WILD-TYPE 19 41 32 71 21

Figure S36.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NBPF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S153.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NBPF3 MUTATED 3 1 3
NBPF3 WILD-TYPE 46 78 65
'NBPF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S154.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NBPF3 MUTATED 5 1 1
NBPF3 WILD-TYPE 86 60 49
'NBPF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0353 (Fisher's exact test), Q value = 1

Table S155.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NBPF3 MUTATED 2 3 0 0 1
NBPF3 WILD-TYPE 34 28 58 35 36

Figure S37.  Get High-res Image Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NBPF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S156.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NBPF3 MUTATED 3 2 1
NBPF3 WILD-TYPE 72 83 36
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S157.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NBPF3 MUTATED 2 2 3
NBPF3 WILD-TYPE 46 74 70
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S158.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NBPF3 MUTATED 1 1 2 2 1
NBPF3 WILD-TYPE 23 52 71 24 20
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S159.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NBPF3 MUTATED 0 3 1 2 1
NBPF3 WILD-TYPE 26 31 39 58 36
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S160.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NBPF3 MUTATED 1 1 2 2 1
NBPF3 WILD-TYPE 22 45 33 69 21
'BCLAF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S161.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BCLAF1 MUTATED 3 5 6
BCLAF1 WILD-TYPE 46 74 62
'BCLAF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S162.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BCLAF1 MUTATED 8 5 1
BCLAF1 WILD-TYPE 83 56 49
'BCLAF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S163.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BCLAF1 MUTATED 1 2 5 4 2
BCLAF1 WILD-TYPE 35 29 53 31 35
'BCLAF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S164.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BCLAF1 MUTATED 5 6 3
BCLAF1 WILD-TYPE 70 79 34
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S165.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BCLAF1 MUTATED 4 5 5
BCLAF1 WILD-TYPE 44 71 68
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S166.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BCLAF1 MUTATED 2 5 4 1 2
BCLAF1 WILD-TYPE 22 48 69 25 19
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S167.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BCLAF1 MUTATED 1 1 3 4 5
BCLAF1 WILD-TYPE 25 33 37 56 32
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S168.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BCLAF1 MUTATED 2 4 2 4 2
BCLAF1 WILD-TYPE 21 42 33 67 20
'SCRN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S169.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SCRN3 MUTATED 4 2 3
SCRN3 WILD-TYPE 45 77 65
'SCRN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S170.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SCRN3 MUTATED 7 1 1
SCRN3 WILD-TYPE 84 60 49
'SCRN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S171.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SCRN3 MUTATED 1 1 5 1 1
SCRN3 WILD-TYPE 35 30 53 34 36
'SCRN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S172.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SCRN3 MUTATED 2 6 1
SCRN3 WILD-TYPE 73 79 36
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S173.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SCRN3 MUTATED 3 4 2
SCRN3 WILD-TYPE 45 72 71
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S174.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SCRN3 MUTATED 1 3 3 0 2
SCRN3 WILD-TYPE 23 50 70 26 19
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S175.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SCRN3 MUTATED 0 2 3 4 0
SCRN3 WILD-TYPE 26 32 37 56 37
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S176.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SCRN3 MUTATED 1 3 1 2 2
SCRN3 WILD-TYPE 22 43 34 69 20
'MUC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S177.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC6 MUTATED 6 6 13
MUC6 WILD-TYPE 43 73 55
'MUC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0854 (Fisher's exact test), Q value = 1

Table S178.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC6 MUTATED 15 8 2
MUC6 WILD-TYPE 76 53 48
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S179.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC6 MUTATED 2 6 7 5 5
MUC6 WILD-TYPE 34 25 51 30 32
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S180.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC6 MUTATED 10 10 5
MUC6 WILD-TYPE 65 75 32
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S181.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC6 MUTATED 7 11 7
MUC6 WILD-TYPE 41 65 66
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S182.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC6 MUTATED 4 8 7 1 5
MUC6 WILD-TYPE 20 45 66 25 16
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S183.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC6 MUTATED 1 3 5 11 5
MUC6 WILD-TYPE 25 31 35 49 32
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S184.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC6 MUTATED 3 7 5 5 5
MUC6 WILD-TYPE 20 39 30 66 17
'UGT2B28 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S185.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
UGT2B28 MUTATED 5 3 3
UGT2B28 WILD-TYPE 44 76 65
'UGT2B28 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S186.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
UGT2B28 MUTATED 3 6 2
UGT2B28 WILD-TYPE 88 55 48
'UGT2B28 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S187.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
UGT2B28 MUTATED 1 1 1 4 4
UGT2B28 WILD-TYPE 35 30 57 31 33
'UGT2B28 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S188.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
UGT2B28 MUTATED 5 2 4
UGT2B28 WILD-TYPE 70 83 33
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S189.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
UGT2B28 MUTATED 0 6 5
UGT2B28 WILD-TYPE 48 70 68
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S190.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
UGT2B28 MUTATED 0 2 6 0 3
UGT2B28 WILD-TYPE 24 51 67 26 18
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S191.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
UGT2B28 MUTATED 1 1 1 5 3
UGT2B28 WILD-TYPE 25 33 39 55 34
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S192.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
UGT2B28 MUTATED 0 2 3 3 3
UGT2B28 WILD-TYPE 23 44 32 68 19
'CDHR5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 1

Table S193.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CDHR5 MUTATED 5 1 5
CDHR5 WILD-TYPE 44 78 63
'CDHR5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S194.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CDHR5 MUTATED 7 4 0
CDHR5 WILD-TYPE 84 57 50
'CDHR5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S195.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CDHR5 MUTATED 2 1 3 2 3
CDHR5 WILD-TYPE 34 30 55 33 34
'CDHR5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S196.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CDHR5 MUTATED 4 4 3
CDHR5 WILD-TYPE 71 81 34
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S197.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CDHR5 MUTATED 3 5 3
CDHR5 WILD-TYPE 45 71 70
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S198.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CDHR5 MUTATED 1 4 3 1 2
CDHR5 WILD-TYPE 23 49 70 25 19
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S199.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CDHR5 MUTATED 1 2 1 5 2
CDHR5 WILD-TYPE 25 32 39 55 35
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S200.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CDHR5 MUTATED 1 3 2 3 2
CDHR5 WILD-TYPE 22 43 33 68 20
'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.024 (Fisher's exact test), Q value = 1

Table S201.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KCTD3 MUTATED 1 0 5
KCTD3 WILD-TYPE 48 79 63

Figure S38.  Get High-res Image Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S202.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KCTD3 MUTATED 3 3 0
KCTD3 WILD-TYPE 88 58 50
'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S203.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KCTD3 MUTATED 0 1 2 1 2
KCTD3 WILD-TYPE 36 30 56 34 35
'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S204.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KCTD3 MUTATED 2 2 2
KCTD3 WILD-TYPE 73 83 35
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S205.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KCTD3 MUTATED 1 4 1
KCTD3 WILD-TYPE 47 72 72
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S206.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KCTD3 MUTATED 0 2 2 0 2
KCTD3 WILD-TYPE 24 51 71 26 19
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S207.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KCTD3 MUTATED 1 0 1 4 0
KCTD3 WILD-TYPE 25 34 39 56 37
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 1

Table S208.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KCTD3 MUTATED 0 2 0 2 2
KCTD3 WILD-TYPE 23 44 35 69 20
'CDC27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S209.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CDC27 MUTATED 5 4 5
CDC27 WILD-TYPE 44 75 63
'CDC27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S210.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CDC27 MUTATED 8 5 1
CDC27 WILD-TYPE 83 56 49
'CDC27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.054 (Fisher's exact test), Q value = 1

Table S211.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CDC27 MUTATED 1 2 1 5 5
CDC27 WILD-TYPE 35 29 57 30 32
'CDC27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00473 (Fisher's exact test), Q value = 1

Table S212.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CDC27 MUTATED 7 1 6
CDC27 WILD-TYPE 68 84 31

Figure S39.  Get High-res Image Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CDC27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S213.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CDC27 MUTATED 1 9 4
CDC27 WILD-TYPE 47 67 69
'CDC27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0196 (Fisher's exact test), Q value = 1

Table S214.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CDC27 MUTATED 1 1 4 3 5
CDC27 WILD-TYPE 23 52 69 23 16

Figure S40.  Get High-res Image Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S215.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CDC27 MUTATED 3 0 1 7 3
CDC27 WILD-TYPE 23 34 39 53 34
'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0577 (Fisher's exact test), Q value = 1

Table S216.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CDC27 MUTATED 1 1 3 4 5
CDC27 WILD-TYPE 22 45 32 67 17
'CR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S217.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CR1 MUTATED 5 7 7
CR1 WILD-TYPE 44 72 61
'CR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S218.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CR1 MUTATED 10 5 4
CR1 WILD-TYPE 81 56 46
'CR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S219.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CR1 MUTATED 3 2 7 1 5
CR1 WILD-TYPE 33 29 51 34 32
'CR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S220.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CR1 MUTATED 5 8 5
CR1 WILD-TYPE 70 77 32
'CR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S221.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CR1 MUTATED 6 9 4
CR1 WILD-TYPE 42 67 69
'CR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S222.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CR1 MUTATED 2 7 4 2 4
CR1 WILD-TYPE 22 46 69 24 17
'CR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S223.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CR1 MUTATED 3 1 3 8 4
CR1 WILD-TYPE 23 33 37 52 33
'CR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S224.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CR1 MUTATED 2 6 3 5 3
CR1 WILD-TYPE 21 40 32 66 19
'TCEAL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 1

Table S225.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TCEAL6 MUTATED 3 0 1
TCEAL6 WILD-TYPE 46 79 67

Figure S41.  Get High-res Image Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TCEAL6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S226.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TCEAL6 MUTATED 4 0 0
TCEAL6 WILD-TYPE 87 61 50
'TCEAL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0622 (Fisher's exact test), Q value = 1

Table S227.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TCEAL6 MUTATED 0 2 0 0 1
TCEAL6 WILD-TYPE 36 29 58 35 36
'TCEAL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S228.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TCEAL6 MUTATED 1 1 1
TCEAL6 WILD-TYPE 74 84 36
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S229.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TCEAL6 MUTATED 2 1 1
TCEAL6 WILD-TYPE 46 75 72
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S230.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TCEAL6 MUTATED 1 0 1 1 1
TCEAL6 WILD-TYPE 23 53 72 25 20
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TCEAL6 MUTATED 0 1 1 1 1
TCEAL6 WILD-TYPE 26 33 39 59 36
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S232.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TCEAL6 MUTATED 1 0 1 1 1
TCEAL6 WILD-TYPE 22 46 34 70 21
'LILRA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S233.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LILRA6 MUTATED 5 4 2
LILRA6 WILD-TYPE 44 75 66
'LILRA6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S234.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LILRA6 MUTATED 8 2 1
LILRA6 WILD-TYPE 83 59 49
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S235.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LILRA6 MUTATED 1 1 3 1 5
LILRA6 WILD-TYPE 35 30 55 34 32
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0781 (Fisher's exact test), Q value = 1

Table S236.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LILRA6 MUTATED 2 4 5
LILRA6 WILD-TYPE 73 81 32
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S237.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LILRA6 MUTATED 3 7 1
LILRA6 WILD-TYPE 45 69 72
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00605 (Fisher's exact test), Q value = 1

Table S238.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LILRA6 MUTATED 1 2 1 2 5
LILRA6 WILD-TYPE 23 51 72 24 16

Figure S42.  Get High-res Image Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LILRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S239.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LILRA6 MUTATED 1 0 1 7 2
LILRA6 WILD-TYPE 25 34 39 53 35
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0374 (Fisher's exact test), Q value = 1

Table S240.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LILRA6 MUTATED 1 2 3 1 4
LILRA6 WILD-TYPE 22 44 32 70 18

Figure S43.  Get High-res Image Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'BIK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S241.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BIK MUTATED 1 0 2
BIK WILD-TYPE 48 79 66
'BIK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S242.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BIK MUTATED 2 1 0
BIK WILD-TYPE 89 60 50
'BIK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 1

Table S243.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BIK MUTATED 0 1 1 1 0
BIK WILD-TYPE 36 30 57 34 37
'BIK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S244.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BIK MUTATED 1 2 0
BIK WILD-TYPE 74 83 37
'BIK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S245.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BIK MUTATED 2 1 0
BIK WILD-TYPE 46 75 73
'BIK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S246.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BIK MUTATED 2 0 1 0 0
BIK WILD-TYPE 22 53 72 26 21
'BIK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S247.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BIK MUTATED 0 0 2 0 1
BIK WILD-TYPE 26 34 38 60 36
'BIK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.03 (Fisher's exact test), Q value = 1

Table S248.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BIK MUTATED 2 0 1 0 0
BIK WILD-TYPE 21 46 34 71 22

Figure S44.  Get High-res Image Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SRRM3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0384 (Fisher's exact test), Q value = 1

Table S249.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SRRM3 MUTATED 3 0 1
SRRM3 WILD-TYPE 46 79 67

Figure S45.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SRRM3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 1

Table S250.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SRRM3 MUTATED 4 0 0
SRRM3 WILD-TYPE 87 61 50
'SRRM3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S251.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SRRM3 MUTATED 0 2 0 1 1
SRRM3 WILD-TYPE 36 29 58 34 36
'SRRM3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S252.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SRRM3 MUTATED 1 1 2
SRRM3 WILD-TYPE 74 84 35
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.085 (Fisher's exact test), Q value = 1

Table S253.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SRRM3 MUTATED 3 1 0
SRRM3 WILD-TYPE 45 75 73
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0222 (Fisher's exact test), Q value = 1

Table S254.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SRRM3 MUTATED 2 0 0 1 1
SRRM3 WILD-TYPE 22 53 73 25 20

Figure S46.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SRRM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S255.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SRRM3 MUTATED 1 0 1 1 1
SRRM3 WILD-TYPE 25 34 39 59 36
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0301 (Fisher's exact test), Q value = 1

Table S256.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SRRM3 MUTATED 2 0 1 0 1
SRRM3 WILD-TYPE 21 46 34 71 21

Figure S47.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S257.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MKI67 MUTATED 4 6 6
MKI67 WILD-TYPE 45 73 62
'MKI67 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S258.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MKI67 MUTATED 9 6 2
MKI67 WILD-TYPE 82 55 48
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S259.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MKI67 MUTATED 2 1 6 2 5
MKI67 WILD-TYPE 34 30 52 33 32
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S260.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MKI67 MUTATED 5 6 5
MKI67 WILD-TYPE 70 79 32
'MKI67 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S261.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MKI67 MUTATED 4 6 7
MKI67 WILD-TYPE 44 70 66
'MKI67 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S262.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MKI67 MUTATED 2 4 4 3 4
MKI67 WILD-TYPE 22 49 69 23 17
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 1

Table S263.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MKI67 MUTATED 5 2 2 7 1
MKI67 WILD-TYPE 21 32 38 53 36
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S264.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MKI67 MUTATED 2 4 1 7 3
MKI67 WILD-TYPE 21 42 34 64 19
'ALDH3B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0117 (Fisher's exact test), Q value = 1

Table S265.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ALDH3B1 MUTATED 4 0 1
ALDH3B1 WILD-TYPE 45 79 67

Figure S48.  Get High-res Image Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ALDH3B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.074 (Fisher's exact test), Q value = 1

Table S266.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ALDH3B1 MUTATED 5 0 0
ALDH3B1 WILD-TYPE 86 61 50
'ALDH3B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S267.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ALDH3B1 MUTATED 0 2 1 0 1
ALDH3B1 WILD-TYPE 36 29 57 35 36
'ALDH3B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S268.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ALDH3B1 MUTATED 1 2 1
ALDH3B1 WILD-TYPE 74 83 36
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S269.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ALDH3B1 MUTATED 2 2 1
ALDH3B1 WILD-TYPE 46 74 72
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S270.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ALDH3B1 MUTATED 1 0 2 1 1
ALDH3B1 WILD-TYPE 23 53 71 25 20
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S271.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ALDH3B1 MUTATED 0 1 1 2 1
ALDH3B1 WILD-TYPE 26 33 39 58 36
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S272.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ALDH3B1 MUTATED 1 0 1 2 1
ALDH3B1 WILD-TYPE 22 46 34 69 21
'POTEG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0931 (Fisher's exact test), Q value = 1

Table S273.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
POTEG MUTATED 6 2 5
POTEG WILD-TYPE 43 77 63
'POTEG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S274.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
POTEG MUTATED 5 6 2
POTEG WILD-TYPE 86 55 48
'POTEG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S275.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
POTEG MUTATED 1 2 3 3 3
POTEG WILD-TYPE 35 29 55 32 34
'POTEG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S276.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
POTEG MUTATED 6 3 3
POTEG WILD-TYPE 69 82 34
'POTEG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S277.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
POTEG MUTATED 2 7 4
POTEG WILD-TYPE 46 69 69
'POTEG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S278.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
POTEG MUTATED 0 3 5 4 1
POTEG WILD-TYPE 24 50 68 22 20
'POTEG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 1

Table S279.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
POTEG MUTATED 1 2 0 5 5
POTEG WILD-TYPE 25 32 40 55 32
'POTEG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S280.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
POTEG MUTATED 0 3 5 4 1
POTEG WILD-TYPE 23 43 30 67 21
'ZNF658 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 1

Table S281.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZNF658 MUTATED 2 0 6
ZNF658 WILD-TYPE 47 79 62

Figure S49.  Get High-res Image Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ZNF658 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S282.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZNF658 MUTATED 5 3 0
ZNF658 WILD-TYPE 86 58 50
'ZNF658 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S283.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZNF658 MUTATED 2 2 1 0 2
ZNF658 WILD-TYPE 34 29 57 35 35
'ZNF658 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S284.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZNF658 MUTATED 4 1 2
ZNF658 WILD-TYPE 71 84 35
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S285.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZNF658 MUTATED 2 3 3
ZNF658 WILD-TYPE 46 73 70
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S286.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZNF658 MUTATED 1 0 3 2 2
ZNF658 WILD-TYPE 23 53 70 24 19
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S287.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZNF658 MUTATED 1 1 1 2 3
ZNF658 WILD-TYPE 25 33 39 58 34
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S288.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZNF658 MUTATED 1 0 2 3 2
ZNF658 WILD-TYPE 22 46 33 68 20
'TCHH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S289.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TCHH MUTATED 6 6 9
TCHH WILD-TYPE 43 73 59
'TCHH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0424 (Fisher's exact test), Q value = 1

Table S290.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TCHH MUTATED 13 8 1
TCHH WILD-TYPE 78 53 49

Figure S50.  Get High-res Image Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TCHH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S291.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TCHH MUTATED 2 4 7 3 6
TCHH WILD-TYPE 34 27 51 32 31
'TCHH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S292.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TCHH MUTATED 7 9 6
TCHH WILD-TYPE 68 76 31
'TCHH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S293.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TCHH MUTATED 5 9 8
TCHH WILD-TYPE 43 67 65
'TCHH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S294.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TCHH MUTATED 2 7 5 2 6
TCHH WILD-TYPE 22 46 68 24 15
'TCHH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S295.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TCHH MUTATED 3 3 3 9 4
TCHH WILD-TYPE 23 31 37 51 33
'TCHH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S296.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TCHH MUTATED 2 5 5 5 5
TCHH WILD-TYPE 21 41 30 66 17
'TMEM176A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S297.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TMEM176A MUTATED 2 0 2
TMEM176A WILD-TYPE 47 79 66
'TMEM176A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S298.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TMEM176A MUTATED 4 0 0
TMEM176A WILD-TYPE 87 61 50
'TMEM176A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S299.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TMEM176A MUTATED 0 2 1 0 0
TMEM176A WILD-TYPE 36 29 57 35 37
'TMEM176A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S300.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TMEM176A MUTATED 1 2 0
TMEM176A WILD-TYPE 74 83 37
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S301.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TMEM176A MUTATED 2 0 2
TMEM176A WILD-TYPE 46 76 71
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S302.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TMEM176A MUTATED 1 1 1 1 0
TMEM176A WILD-TYPE 23 52 72 25 21
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 1

Table S303.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TMEM176A MUTATED 0 2 1 0 1
TMEM176A WILD-TYPE 26 32 39 60 36
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S304.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TMEM176A MUTATED 1 1 1 1 0
TMEM176A WILD-TYPE 22 45 34 70 22
'RP1L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S305.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RP1L1 MUTATED 6 5 9
RP1L1 WILD-TYPE 43 74 59
'RP1L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.061 (Fisher's exact test), Q value = 1

Table S306.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RP1L1 MUTATED 12 8 1
RP1L1 WILD-TYPE 79 53 49
'RP1L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S307.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RP1L1 MUTATED 0 5 6 8 2
RP1L1 WILD-TYPE 36 26 52 27 35

Figure S51.  Get High-res Image Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RP1L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S308.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RP1L1 MUTATED 9 10 2
RP1L1 WILD-TYPE 66 75 35
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S309.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RP1L1 MUTATED 5 10 6
RP1L1 WILD-TYPE 43 66 67
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S310.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RP1L1 MUTATED 2 8 6 3 2
RP1L1 WILD-TYPE 22 45 67 23 19
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S311.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RP1L1 MUTATED 2 1 7 6 5
RP1L1 WILD-TYPE 24 33 33 54 32
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S312.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RP1L1 MUTATED 2 8 5 4 2
RP1L1 WILD-TYPE 21 38 30 67 20
'TSC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S313.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TSC2 MUTATED 2 9 4
TSC2 WILD-TYPE 47 70 64
'TSC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0452 (Fisher's exact test), Q value = 1

Table S314.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TSC2 MUTATED 7 1 7
TSC2 WILD-TYPE 84 60 43

Figure S52.  Get High-res Image Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TSC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S315.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TSC2 MUTATED 5 3 4 2 1
TSC2 WILD-TYPE 31 28 54 33 36
'TSC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S316.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TSC2 MUTATED 7 7 1
TSC2 WILD-TYPE 68 78 36
'TSC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S317.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TSC2 MUTATED 3 7 5
TSC2 WILD-TYPE 45 69 68
'TSC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S318.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TSC2 MUTATED 2 5 7 0 1
TSC2 WILD-TYPE 22 48 66 26 20
'TSC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S319.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TSC2 MUTATED 0 3 3 6 3
TSC2 WILD-TYPE 26 31 37 54 34
'TSC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S320.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TSC2 MUTATED 2 4 2 4 3
TSC2 WILD-TYPE 21 42 33 67 19
'PRKDC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S321.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRKDC MUTATED 5 9 9
PRKDC WILD-TYPE 44 70 59
'PRKDC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S322.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRKDC MUTATED 15 6 3
PRKDC WILD-TYPE 76 55 47
'PRKDC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S323.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRKDC MUTATED 2 5 8 3 5
PRKDC WILD-TYPE 34 26 50 32 32
'PRKDC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S324.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRKDC MUTATED 8 10 5
PRKDC WILD-TYPE 67 75 32
'PRKDC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S325.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRKDC MUTATED 6 9 9
PRKDC WILD-TYPE 42 67 64
'PRKDC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S326.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRKDC MUTATED 1 7 6 6 4
PRKDC WILD-TYPE 23 46 67 20 17
'PRKDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S327.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRKDC MUTATED 3 2 5 10 4
PRKDC WILD-TYPE 23 32 35 50 33
'PRKDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S328.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRKDC MUTATED 1 7 6 6 4
PRKDC WILD-TYPE 22 39 29 65 18
'NRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S329.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NRD1 MUTATED 4 5 2
NRD1 WILD-TYPE 45 74 66
'NRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S330.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NRD1 MUTATED 5 4 2
NRD1 WILD-TYPE 86 57 48
'NRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S331.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NRD1 MUTATED 2 2 2 2 3
NRD1 WILD-TYPE 34 29 56 33 34
'NRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S332.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NRD1 MUTATED 6 2 3
NRD1 WILD-TYPE 69 83 34
'NRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S333.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NRD1 MUTATED 3 5 3
NRD1 WILD-TYPE 45 71 70
'NRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S334.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NRD1 MUTATED 1 2 3 1 4
NRD1 WILD-TYPE 23 51 70 25 17
'NRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S335.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NRD1 MUTATED 0 3 3 4 1
NRD1 WILD-TYPE 26 31 37 56 36
'NRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0804 (Fisher's exact test), Q value = 1

Table S336.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NRD1 MUTATED 1 2 0 4 4
NRD1 WILD-TYPE 22 44 35 67 18
'TAS2R20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S337.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TAS2R20 MUTATED 1 3 0
TAS2R20 WILD-TYPE 48 76 68
'TAS2R20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S338.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TAS2R20 MUTATED 2 0 2
TAS2R20 WILD-TYPE 89 61 48
'TAS2R20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S339.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TAS2R20 MUTATED 0 1 1 0 2
TAS2R20 WILD-TYPE 36 30 57 35 35
'TAS2R20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0106 (Fisher's exact test), Q value = 1

Table S340.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TAS2R20 MUTATED 1 0 3
TAS2R20 WILD-TYPE 74 85 34

Figure S53.  Get High-res Image Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S341.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TAS2R20 MUTATED 1 1 2
TAS2R20 WILD-TYPE 47 75 71
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0829 (Fisher's exact test), Q value = 1

Table S342.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TAS2R20 MUTATED 0 0 1 1 2
TAS2R20 WILD-TYPE 24 53 72 25 19
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S343.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TAS2R20 MUTATED 1 0 0 2 1
TAS2R20 WILD-TYPE 25 34 40 58 36
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S344.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TAS2R20 MUTATED 0 0 1 2 1
TAS2R20 WILD-TYPE 23 46 34 69 21
'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S345.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PTEN MUTATED 1 2 6
PTEN WILD-TYPE 48 77 62
'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0982 (Fisher's exact test), Q value = 1

Table S346.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PTEN MUTATED 5 5 0
PTEN WILD-TYPE 86 56 50
'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S347.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PTEN MUTATED 1 1 4 2 1
PTEN WILD-TYPE 35 30 54 33 36
'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S348.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PTEN MUTATED 3 5 1
PTEN WILD-TYPE 72 80 36
'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S349.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PTEN MUTATED 3 2 5
PTEN WILD-TYPE 45 74 68
'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S350.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PTEN MUTATED 0 3 4 2 1
PTEN WILD-TYPE 24 50 69 24 20
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S351.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PTEN MUTATED 1 1 2 3 3
PTEN WILD-TYPE 25 33 38 57 34
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S352.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PTEN MUTATED 0 3 1 5 1
PTEN WILD-TYPE 23 43 34 66 21
'CYFIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S353.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CYFIP2 MUTATED 4 4 5
CYFIP2 WILD-TYPE 45 75 63
'CYFIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S354.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CYFIP2 MUTATED 7 4 2
CYFIP2 WILD-TYPE 84 57 48
'CYFIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S355.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CYFIP2 MUTATED 4 2 2 2 2
CYFIP2 WILD-TYPE 32 29 56 33 35
'CYFIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S356.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CYFIP2 MUTATED 7 3 2
CYFIP2 WILD-TYPE 68 82 35
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S357.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CYFIP2 MUTATED 3 2 7
CYFIP2 WILD-TYPE 45 74 66
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S358.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CYFIP2 MUTATED 1 2 6 2 1
CYFIP2 WILD-TYPE 23 51 67 24 20
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S359.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CYFIP2 MUTATED 2 1 1 3 5
CYFIP2 WILD-TYPE 24 33 39 57 32
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S360.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CYFIP2 MUTATED 1 1 2 7 1
CYFIP2 WILD-TYPE 22 45 33 64 21
'PRAMEF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S361.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRAMEF1 MUTATED 2 4 3
PRAMEF1 WILD-TYPE 47 75 65
'PRAMEF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S362.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRAMEF1 MUTATED 6 2 1
PRAMEF1 WILD-TYPE 85 59 49
'PRAMEF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S363.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRAMEF1 MUTATED 0 1 3 1 4
PRAMEF1 WILD-TYPE 36 30 55 34 33
'PRAMEF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S364.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRAMEF1 MUTATED 2 3 4
PRAMEF1 WILD-TYPE 73 82 33
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S365.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRAMEF1 MUTATED 2 5 2
PRAMEF1 WILD-TYPE 46 71 71
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0206 (Fisher's exact test), Q value = 1

Table S366.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRAMEF1 MUTATED 0 3 1 1 4
PRAMEF1 WILD-TYPE 24 50 72 25 17

Figure S54.  Get High-res Image Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0642 (Fisher's exact test), Q value = 1

Table S367.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRAMEF1 MUTATED 2 0 0 6 1
PRAMEF1 WILD-TYPE 24 34 40 54 36
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S368.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRAMEF1 MUTATED 0 3 1 2 3
PRAMEF1 WILD-TYPE 23 43 34 69 19
'MST1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S369.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MST1 MUTATED 3 4 1
MST1 WILD-TYPE 46 75 67
'MST1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S370.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MST1 MUTATED 5 1 2
MST1 WILD-TYPE 86 60 48
'MST1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S371.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MST1 MUTATED 1 2 2 0 2
MST1 WILD-TYPE 35 29 56 35 35
'MST1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S372.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MST1 MUTATED 2 3 2
MST1 WILD-TYPE 73 82 35
'MST1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S373.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MST1 MUTATED 2 4 2
MST1 WILD-TYPE 46 72 71
'MST1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S374.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MST1 MUTATED 1 2 2 1 2
MST1 WILD-TYPE 23 51 71 25 19
'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S375.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MST1 MUTATED 1 1 1 3 2
MST1 WILD-TYPE 25 33 39 57 35
'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S376.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MST1 MUTATED 1 1 2 3 1
MST1 WILD-TYPE 22 45 33 68 21
'ZC3H7A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S377.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZC3H7A MUTATED 5 5 2
ZC3H7A WILD-TYPE 44 74 66
'ZC3H7A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S378.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZC3H7A MUTATED 7 3 2
ZC3H7A WILD-TYPE 84 58 48
'ZC3H7A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S379.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZC3H7A MUTATED 1 2 3 2 4
ZC3H7A WILD-TYPE 35 29 55 33 33
'ZC3H7A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S380.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZC3H7A MUTATED 4 5 3
ZC3H7A WILD-TYPE 71 80 34
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 1

Table S381.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZC3H7A MUTATED 3 7 2
ZC3H7A WILD-TYPE 45 69 71
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S382.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZC3H7A MUTATED 1 4 3 2 2
ZC3H7A WILD-TYPE 23 49 70 24 19
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 1

Table S383.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZC3H7A MUTATED 1 0 2 7 2
ZC3H7A WILD-TYPE 25 34 38 53 35
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S384.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZC3H7A MUTATED 1 4 4 1 2
ZC3H7A WILD-TYPE 22 42 31 70 20
'MLL3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S385.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MLL3 MUTATED 9 9 12
MLL3 WILD-TYPE 40 70 56
'MLL3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S386.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MLL3 MUTATED 14 11 5
MLL3 WILD-TYPE 77 50 45
'MLL3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0177 (Fisher's exact test), Q value = 1

Table S387.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MLL3 MUTATED 1 10 7 6 6
MLL3 WILD-TYPE 35 21 51 29 31

Figure S55.  Get High-res Image Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MLL3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S388.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MLL3 MUTATED 13 10 7
MLL3 WILD-TYPE 62 75 30
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S389.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MLL3 MUTATED 8 12 10
MLL3 WILD-TYPE 40 64 63
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S390.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MLL3 MUTATED 4 8 8 5 5
MLL3 WILD-TYPE 20 45 65 21 16
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S391.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MLL3 MUTATED 4 1 8 9 8
MLL3 WILD-TYPE 22 33 32 51 29
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S392.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MLL3 MUTATED 4 7 6 9 4
MLL3 WILD-TYPE 19 39 29 62 18
'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S393.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HNRNPCL1 MUTATED 1 3 7
HNRNPCL1 WILD-TYPE 48 76 61
'HNRNPCL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S394.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HNRNPCL1 MUTATED 5 4 2
HNRNPCL1 WILD-TYPE 86 57 48
'HNRNPCL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S395.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HNRNPCL1 MUTATED 2 0 4 3 1
HNRNPCL1 WILD-TYPE 34 31 54 32 36
'HNRNPCL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S396.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HNRNPCL1 MUTATED 5 4 1
HNRNPCL1 WILD-TYPE 70 81 36
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S397.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HNRNPCL1 MUTATED 1 3 7
HNRNPCL1 WILD-TYPE 47 73 66
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S398.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HNRNPCL1 MUTATED 0 3 7 0 1
HNRNPCL1 WILD-TYPE 24 50 66 26 20
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S399.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HNRNPCL1 MUTATED 1 3 1 3 3
HNRNPCL1 WILD-TYPE 25 31 39 57 34
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S400.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HNRNPCL1 MUTATED 0 3 2 5 1
HNRNPCL1 WILD-TYPE 23 43 33 66 21
'TUBA3E MUTATION STATUS' versus 'CN_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S401.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TUBA3E MUTATED 2 2 3
TUBA3E WILD-TYPE 47 77 65
'TUBA3E MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S402.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TUBA3E MUTATED 4 2 1
TUBA3E WILD-TYPE 87 59 49
'TUBA3E MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S403.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TUBA3E MUTATED 0 1 1 1 4
TUBA3E WILD-TYPE 36 30 57 34 33
'TUBA3E MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0658 (Fisher's exact test), Q value = 1

Table S404.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TUBA3E MUTATED 1 2 4
TUBA3E WILD-TYPE 74 83 33
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S405.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TUBA3E MUTATED 1 4 2
TUBA3E WILD-TYPE 47 72 71
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00747 (Fisher's exact test), Q value = 1

Table S406.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TUBA3E MUTATED 1 1 1 0 4
TUBA3E WILD-TYPE 23 52 72 26 17

Figure S56.  Get High-res Image Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TUBA3E MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S407.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TUBA3E MUTATED 2 0 1 4 0
TUBA3E WILD-TYPE 24 34 39 56 37
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S408.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TUBA3E MUTATED 1 1 0 2 3
TUBA3E WILD-TYPE 22 45 35 69 19
'MUC21 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S409.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC21 MUTATED 3 5 7
MUC21 WILD-TYPE 46 74 61
'MUC21 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S410.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC21 MUTATED 7 5 4
MUC21 WILD-TYPE 84 56 46
'MUC21 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S411.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC21 MUTATED 4 3 4 2 2
MUC21 WILD-TYPE 32 28 54 33 35
'MUC21 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S412.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC21 MUTATED 4 9 2
MUC21 WILD-TYPE 71 76 35
'MUC21 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S413.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC21 MUTATED 3 7 6
MUC21 WILD-TYPE 45 69 67
'MUC21 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S414.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC21 MUTATED 2 5 5 1 3
MUC21 WILD-TYPE 22 48 68 25 18
'MUC21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S415.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC21 MUTATED 3 4 3 5 1
MUC21 WILD-TYPE 23 30 37 55 36
'MUC21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S416.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC21 MUTATED 2 4 1 6 3
MUC21 WILD-TYPE 21 42 34 65 19
'HPS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S417.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HPS4 MUTATED 1 4 0
HPS4 WILD-TYPE 48 75 68
'HPS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S418.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HPS4 MUTATED 0 3 2
HPS4 WILD-TYPE 91 58 48
'HPS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S419.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HPS4 MUTATED 1 0 1 0 3
HPS4 WILD-TYPE 35 31 57 35 34
'HPS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S420.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HPS4 MUTATED 1 1 3
HPS4 WILD-TYPE 74 84 34
'HPS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S421.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HPS4 MUTATED 0 3 2
HPS4 WILD-TYPE 48 73 71
'HPS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S422.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HPS4 MUTATED 0 1 1 1 2
HPS4 WILD-TYPE 24 52 72 25 19
'HPS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S423.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HPS4 MUTATED 1 0 1 2 1
HPS4 WILD-TYPE 25 34 39 58 36
'HPS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S424.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HPS4 MUTATED 0 1 1 2 1
HPS4 WILD-TYPE 23 45 34 69 21
'OR2T4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0162 (Fisher's exact test), Q value = 1

Table S425.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2T4 MUTATED 5 1 8
OR2T4 WILD-TYPE 44 78 60

Figure S57.  Get High-res Image Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'OR2T4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0546 (Fisher's exact test), Q value = 1

Table S426.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2T4 MUTATED 8 6 0
OR2T4 WILD-TYPE 83 55 50
'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0532 (Fisher's exact test), Q value = 1

Table S427.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2T4 MUTATED 2 1 1 4 6
OR2T4 WILD-TYPE 34 30 57 31 31
'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0128 (Fisher's exact test), Q value = 1

Table S428.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2T4 MUTATED 4 3 7
OR2T4 WILD-TYPE 71 82 30

Figure S58.  Get High-res Image Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S429.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2T4 MUTATED 3 4 7
OR2T4 WILD-TYPE 45 72 66
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S430.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2T4 MUTATED 2 2 4 2 4
OR2T4 WILD-TYPE 22 51 69 24 17
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S431.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2T4 MUTATED 3 3 1 5 2
OR2T4 WILD-TYPE 23 31 39 55 35
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S432.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2T4 MUTATED 2 1 3 4 4
OR2T4 WILD-TYPE 21 45 32 67 18
'SPDYE1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S433.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SPDYE1 MUTATED 2 2 0
SPDYE1 WILD-TYPE 47 77 68
'SPDYE1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S434.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SPDYE1 MUTATED 3 0 1
SPDYE1 WILD-TYPE 88 61 49
'SPDYE1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S435.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SPDYE1 MUTATED 0 1 1 0 2
SPDYE1 WILD-TYPE 36 30 57 35 35
'SPDYE1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S436.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SPDYE1 MUTATED 0 2 2
SPDYE1 WILD-TYPE 75 83 35
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S437.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SPDYE1 MUTATED 0 3 1
SPDYE1 WILD-TYPE 48 73 72
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0425 (Fisher's exact test), Q value = 1

Table S438.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SPDYE1 MUTATED 0 2 0 0 2
SPDYE1 WILD-TYPE 24 51 73 26 19

Figure S59.  Get High-res Image Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S439.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SPDYE1 MUTATED 1 0 1 2 0
SPDYE1 WILD-TYPE 25 34 39 58 37
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S440.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SPDYE1 MUTATED 0 2 0 1 1
SPDYE1 WILD-TYPE 23 44 35 70 21
'COG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S441.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
COG2 MUTATED 3 1 2
COG2 WILD-TYPE 46 78 66
'COG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S442.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
COG2 MUTATED 5 0 1
COG2 WILD-TYPE 86 61 49
'COG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S443.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
COG2 MUTATED 1 2 1 0 1
COG2 WILD-TYPE 35 29 57 35 36
'COG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S444.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
COG2 MUTATED 1 3 1
COG2 WILD-TYPE 74 82 36
'COG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0742 (Fisher's exact test), Q value = 1

Table S445.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
COG2 MUTATED 4 1 1
COG2 WILD-TYPE 44 75 72
'COG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S446.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
COG2 MUTATED 2 1 1 1 1
COG2 WILD-TYPE 22 52 72 25 20
'COG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S447.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
COG2 MUTATED 0 1 3 1 1
COG2 WILD-TYPE 26 33 37 59 36
'COG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S448.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
COG2 MUTATED 2 1 1 1 1
COG2 WILD-TYPE 21 45 34 70 21
'SEC63 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0535 (Fisher's exact test), Q value = 1

Table S449.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SEC63 MUTATED 6 2 2
SEC63 WILD-TYPE 43 77 66
'SEC63 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0886 (Fisher's exact test), Q value = 1

Table S450.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SEC63 MUTATED 8 1 1
SEC63 WILD-TYPE 83 60 49
'SEC63 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S451.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SEC63 MUTATED 0 3 1 2 2
SEC63 WILD-TYPE 36 28 57 33 35
'SEC63 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S452.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SEC63 MUTATED 2 4 2
SEC63 WILD-TYPE 73 81 35
'SEC63 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S453.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SEC63 MUTATED 4 3 3
SEC63 WILD-TYPE 44 73 70
'SEC63 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S454.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SEC63 MUTATED 2 3 1 3 1
SEC63 WILD-TYPE 22 50 72 23 20
'SEC63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S455.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SEC63 MUTATED 1 2 3 2 2
SEC63 WILD-TYPE 25 32 37 58 35
'SEC63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S456.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SEC63 MUTATED 2 2 2 3 1
SEC63 WILD-TYPE 21 44 33 68 21
'LILRA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S457.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LILRA3 MUTATED 2 2 0
LILRA3 WILD-TYPE 47 77 68
'LILRA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S458.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LILRA3 MUTATED 4 0 1
LILRA3 WILD-TYPE 87 61 49
'LILRA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0226 (Fisher's exact test), Q value = 1

Table S459.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LILRA3 MUTATED 0 0 1 0 4
LILRA3 WILD-TYPE 36 31 57 35 33

Figure S60.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'LILRA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00464 (Fisher's exact test), Q value = 1

Table S460.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LILRA3 MUTATED 0 1 4
LILRA3 WILD-TYPE 75 84 33

Figure S61.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'LILRA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S461.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LILRA3 MUTATED 0 3 2
LILRA3 WILD-TYPE 48 73 71
'LILRA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00899 (Fisher's exact test), Q value = 1

Table S462.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LILRA3 MUTATED 0 2 0 0 3
LILRA3 WILD-TYPE 24 51 73 26 18

Figure S62.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LILRA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S463.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LILRA3 MUTATED 1 0 0 4 0
LILRA3 WILD-TYPE 25 34 40 56 37
'LILRA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S464.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LILRA3 MUTATED 0 2 0 1 2
LILRA3 WILD-TYPE 23 44 35 70 20
'CYP2A6 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S465.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CYP2A6 MUTATED 1 3 2
CYP2A6 WILD-TYPE 48 76 66
'CYP2A6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S466.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CYP2A6 MUTATED 3 0 3
CYP2A6 WILD-TYPE 88 61 47
'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S467.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CYP2A6 MUTATED 1 1 3 0 1
CYP2A6 WILD-TYPE 35 30 55 35 36
'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0741 (Fisher's exact test), Q value = 1

Table S468.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CYP2A6 MUTATED 0 5 1
CYP2A6 WILD-TYPE 75 80 36
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S469.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CYP2A6 MUTATED 1 3 2
CYP2A6 WILD-TYPE 47 73 71
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S470.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CYP2A6 MUTATED 1 3 2 0 0
CYP2A6 WILD-TYPE 23 50 71 26 21
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S471.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CYP2A6 MUTATED 2 1 1 2 0
CYP2A6 WILD-TYPE 24 33 39 58 37
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S472.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CYP2A6 MUTATED 1 3 0 2 0
CYP2A6 WILD-TYPE 22 43 35 69 22
'ZC3H11A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 1

Table S473.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZC3H11A MUTATED 0 2 3
ZC3H11A WILD-TYPE 49 77 65
'ZC3H11A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S474.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZC3H11A MUTATED 1 3 2
ZC3H11A WILD-TYPE 90 58 48
'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S475.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZC3H11A MUTATED 1 2 0 2 1
ZC3H11A WILD-TYPE 35 29 58 33 36
'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S476.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZC3H11A MUTATED 4 1 1
ZC3H11A WILD-TYPE 71 84 36
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S477.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZC3H11A MUTATED 1 2 3
ZC3H11A WILD-TYPE 47 74 70
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S478.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZC3H11A MUTATED 1 0 3 2 0
ZC3H11A WILD-TYPE 23 53 70 24 21
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S479.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZC3H11A MUTATED 1 1 1 1 2
ZC3H11A WILD-TYPE 25 33 39 59 35
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S480.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZC3H11A MUTATED 1 0 3 2 0
ZC3H11A WILD-TYPE 22 46 32 69 22
'LCE4A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S481.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LCE4A MUTATED 5 3 2
LCE4A WILD-TYPE 44 76 66
'LCE4A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S482.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LCE4A MUTATED 6 3 1
LCE4A WILD-TYPE 85 58 49
'LCE4A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S483.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LCE4A MUTATED 2 3 1 2 1
LCE4A WILD-TYPE 34 28 57 33 36
'LCE4A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S484.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LCE4A MUTATED 4 4 1
LCE4A WILD-TYPE 71 81 36
'LCE4A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S485.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LCE4A MUTATED 3 3 4
LCE4A WILD-TYPE 45 73 69
'LCE4A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S486.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LCE4A MUTATED 2 2 5 0 1
LCE4A WILD-TYPE 22 51 68 26 20
'LCE4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0521 (Fisher's exact test), Q value = 1

Table S487.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LCE4A MUTATED 0 4 4 2 0
LCE4A WILD-TYPE 26 30 36 58 37
'LCE4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S488.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LCE4A MUTATED 2 2 1 4 1
LCE4A WILD-TYPE 21 44 34 67 21
'ATXN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S489.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ATXN3 MUTATED 0 5 1
ATXN3 WILD-TYPE 49 74 67
'ATXN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S490.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ATXN3 MUTATED 1 3 2
ATXN3 WILD-TYPE 90 58 48
'ATXN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S491.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ATXN3 MUTATED 2 0 2 1 1
ATXN3 WILD-TYPE 34 31 56 34 36
'ATXN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S492.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ATXN3 MUTATED 3 2 1
ATXN3 WILD-TYPE 72 83 36
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S493.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ATXN3 MUTATED 0 3 3
ATXN3 WILD-TYPE 48 73 70
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S494.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ATXN3 MUTATED 0 2 2 1 1
ATXN3 WILD-TYPE 24 51 71 25 20
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S495.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ATXN3 MUTATED 1 0 0 2 3
ATXN3 WILD-TYPE 25 34 40 58 34
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S496.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ATXN3 MUTATED 0 1 1 4 0
ATXN3 WILD-TYPE 23 45 34 67 22
'GTF2IRD2B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0648 (Fisher's exact test), Q value = 1

Table S497.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GTF2IRD2B MUTATED 3 0 2
GTF2IRD2B WILD-TYPE 46 79 66
'GTF2IRD2B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0728 (Fisher's exact test), Q value = 1

Table S498.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GTF2IRD2B MUTATED 5 0 0
GTF2IRD2B WILD-TYPE 86 61 50
'GTF2IRD2B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S499.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GTF2IRD2B MUTATED 0 2 0 1 1
GTF2IRD2B WILD-TYPE 36 29 58 34 36
'GTF2IRD2B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S500.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GTF2IRD2B MUTATED 1 1 2
GTF2IRD2B WILD-TYPE 74 84 35
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S501.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GTF2IRD2B MUTATED 3 1 1
GTF2IRD2B WILD-TYPE 45 75 72
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S502.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GTF2IRD2B MUTATED 2 0 1 1 1
GTF2IRD2B WILD-TYPE 22 53 72 25 20
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S503.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GTF2IRD2B MUTATED 1 1 1 1 1
GTF2IRD2B WILD-TYPE 25 33 39 59 36
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S504.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GTF2IRD2B MUTATED 2 0 1 1 1
GTF2IRD2B WILD-TYPE 21 46 34 70 21
'QRICH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S505.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
QRICH2 MUTATED 3 11 5
QRICH2 WILD-TYPE 46 68 63
'QRICH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S506.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
QRICH2 MUTATED 10 3 6
QRICH2 WILD-TYPE 81 58 44
'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S507.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
QRICH2 MUTATED 2 2 6 1 7
QRICH2 WILD-TYPE 34 29 52 34 30
'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S508.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
QRICH2 MUTATED 5 7 6
QRICH2 WILD-TYPE 70 78 31
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S509.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
QRICH2 MUTATED 6 8 5
QRICH2 WILD-TYPE 42 68 68
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S510.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
QRICH2 MUTATED 2 6 4 2 5
QRICH2 WILD-TYPE 22 47 69 24 16
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S511.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
QRICH2 MUTATED 2 3 2 11 1
QRICH2 WILD-TYPE 24 31 38 49 36
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S512.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
QRICH2 MUTATED 2 6 2 5 4
QRICH2 WILD-TYPE 21 40 33 66 18
'PLAU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S513.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PLAU MUTATED 2 1 3
PLAU WILD-TYPE 47 78 65
'PLAU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S514.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PLAU MUTATED 4 1 1
PLAU WILD-TYPE 87 60 49
'PLAU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 1

Table S515.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PLAU MUTATED 1 2 0 1 1
PLAU WILD-TYPE 35 29 58 34 36
'PLAU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S516.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PLAU MUTATED 2 2 1
PLAU WILD-TYPE 73 83 36
'PLAU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S517.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PLAU MUTATED 1 2 3
PLAU WILD-TYPE 47 74 70
'PLAU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S518.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PLAU MUTATED 1 1 3 0 1
PLAU WILD-TYPE 23 52 70 26 20
'PLAU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S519.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PLAU MUTATED 0 2 1 2 1
PLAU WILD-TYPE 26 32 39 58 36
'PLAU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S520.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PLAU MUTATED 1 1 1 2 1
PLAU WILD-TYPE 22 45 34 69 21
'MAPKAPK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S521.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MAPKAPK2 MUTATED 0 3 1
MAPKAPK2 WILD-TYPE 49 76 67
'MAPKAPK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S522.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MAPKAPK2 MUTATED 2 2 0
MAPKAPK2 WILD-TYPE 89 59 50
'MAPKAPK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S523.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MAPKAPK2 MUTATED 0 0 2 1 1
MAPKAPK2 WILD-TYPE 36 31 56 34 36
'MAPKAPK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S524.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MAPKAPK2 MUTATED 1 2 1
MAPKAPK2 WILD-TYPE 74 83 36
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S525.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MAPKAPK2 MUTATED 0 3 1
MAPKAPK2 WILD-TYPE 48 73 72
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S526.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MAPKAPK2 MUTATED 0 1 2 0 1
MAPKAPK2 WILD-TYPE 24 52 71 26 20
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S527.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MAPKAPK2 MUTATED 0 1 0 2 1
MAPKAPK2 WILD-TYPE 26 33 40 58 36
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S528.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MAPKAPK2 MUTATED 0 1 2 0 1
MAPKAPK2 WILD-TYPE 23 45 33 71 21
'NAP1L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S529.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NAP1L1 MUTATED 2 1 3
NAP1L1 WILD-TYPE 47 78 65
'NAP1L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S530.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NAP1L1 MUTATED 3 2 1
NAP1L1 WILD-TYPE 88 59 49
'NAP1L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S531.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NAP1L1 MUTATED 0 2 0 1 1
NAP1L1 WILD-TYPE 36 29 58 34 36
'NAP1L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S532.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NAP1L1 MUTATED 2 1 1
NAP1L1 WILD-TYPE 73 84 36
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S533.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NAP1L1 MUTATED 3 2 1
NAP1L1 WILD-TYPE 45 74 72
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S534.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NAP1L1 MUTATED 1 1 2 1 1
NAP1L1 WILD-TYPE 23 52 71 25 20
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S535.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NAP1L1 MUTATED 0 1 2 1 2
NAP1L1 WILD-TYPE 26 33 38 59 35
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S536.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NAP1L1 MUTATED 1 1 2 1 1
NAP1L1 WILD-TYPE 22 45 33 70 21
'FAM118A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S537.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FAM118A MUTATED 0 2 2
FAM118A WILD-TYPE 49 77 66
'FAM118A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S538.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FAM118A MUTATED 1 2 1
FAM118A WILD-TYPE 90 59 49
'FAM118A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S539.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FAM118A MUTATED 0 0 1 2 1
FAM118A WILD-TYPE 36 31 57 33 36
'FAM118A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S540.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FAM118A MUTATED 2 1 1
FAM118A WILD-TYPE 73 84 36
'FAM118A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S541.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FAM118A MUTATED 0 1 3
FAM118A WILD-TYPE 48 75 70
'FAM118A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S542.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FAM118A MUTATED 0 1 1 1 1
FAM118A WILD-TYPE 24 52 72 25 20
'FAM118A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S543.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FAM118A MUTATED 2 0 0 1 1
FAM118A WILD-TYPE 24 34 40 59 36
'FAM118A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S544.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FAM118A MUTATED 0 1 1 2 0
FAM118A WILD-TYPE 23 45 34 69 22
'SLC7A6OS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S545.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SLC7A6OS MUTATED 1 2 1
SLC7A6OS WILD-TYPE 48 77 67
'SLC7A6OS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S546.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SLC7A6OS MUTATED 2 1 1
SLC7A6OS WILD-TYPE 89 60 49
'SLC7A6OS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0375 (Fisher's exact test), Q value = 1

Table S547.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SLC7A6OS MUTATED 0 3 1 0 0
SLC7A6OS WILD-TYPE 36 28 57 35 37

Figure S63.  Get High-res Image Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SLC7A6OS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S548.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SLC7A6OS MUTATED 3 1 0
SLC7A6OS WILD-TYPE 72 84 37
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S549.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SLC7A6OS MUTATED 1 3 0
SLC7A6OS WILD-TYPE 47 73 73
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S550.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SLC7A6OS MUTATED 0 2 1 1 0
SLC7A6OS WILD-TYPE 24 51 72 25 21
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S551.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SLC7A6OS MUTATED 0 0 0 2 2
SLC7A6OS WILD-TYPE 26 34 40 58 35
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S552.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SLC7A6OS MUTATED 0 1 2 1 0
SLC7A6OS WILD-TYPE 23 45 33 70 22
'NBPF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S553.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NBPF10 MUTATED 1 4 7
NBPF10 WILD-TYPE 48 75 61
'NBPF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S554.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NBPF10 MUTATED 7 3 2
NBPF10 WILD-TYPE 84 58 48
'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S555.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NBPF10 MUTATED 2 2 4 2 2
NBPF10 WILD-TYPE 34 29 54 33 35
'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S556.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NBPF10 MUTATED 5 5 2
NBPF10 WILD-TYPE 70 80 35
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S557.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NBPF10 MUTATED 3 3 6
NBPF10 WILD-TYPE 45 73 67
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S558.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NBPF10 MUTATED 1 2 4 2 3
NBPF10 WILD-TYPE 23 51 69 24 18
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S559.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NBPF10 MUTATED 3 1 1 5 2
NBPF10 WILD-TYPE 23 33 39 55 35
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S560.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NBPF10 MUTATED 1 2 1 6 2
NBPF10 WILD-TYPE 22 44 34 65 20
'ZXDC MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S561.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZXDC MUTATED 1 3 2
ZXDC WILD-TYPE 48 76 66
'ZXDC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S562.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZXDC MUTATED 5 1 0
ZXDC WILD-TYPE 86 60 50
'ZXDC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S563.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZXDC MUTATED 0 1 2 0 3
ZXDC WILD-TYPE 36 30 56 35 34
'ZXDC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S564.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZXDC MUTATED 1 3 2
ZXDC WILD-TYPE 74 82 35
'ZXDC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00862 (Fisher's exact test), Q value = 1

Table S565.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZXDC MUTATED 0 6 0
ZXDC WILD-TYPE 48 70 73

Figure S64.  Get High-res Image Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ZXDC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0371 (Fisher's exact test), Q value = 1

Table S566.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZXDC MUTATED 0 2 0 2 2
ZXDC WILD-TYPE 24 51 73 24 19

Figure S65.  Get High-res Image Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ZXDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S567.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZXDC MUTATED 0 0 1 5 0
ZXDC WILD-TYPE 26 34 39 55 37
'ZXDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0647 (Fisher's exact test), Q value = 1

Table S568.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZXDC MUTATED 0 2 2 0 2
ZXDC WILD-TYPE 23 44 33 71 20
'TAS2R30 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S569.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TAS2R30 MUTATED 2 3 3
TAS2R30 WILD-TYPE 47 76 65
'TAS2R30 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S570.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TAS2R30 MUTATED 3 3 2
TAS2R30 WILD-TYPE 88 58 48
'TAS2R30 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S571.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TAS2R30 MUTATED 2 1 1 3 1
TAS2R30 WILD-TYPE 34 30 57 32 36
'TAS2R30 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S572.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TAS2R30 MUTATED 4 3 1
TAS2R30 WILD-TYPE 71 82 36
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S573.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TAS2R30 MUTATED 1 3 4
TAS2R30 WILD-TYPE 47 73 69
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S574.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TAS2R30 MUTATED 1 2 3 1 1
TAS2R30 WILD-TYPE 23 51 70 25 20
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S575.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TAS2R30 MUTATED 3 0 2 1 2
TAS2R30 WILD-TYPE 23 34 38 59 35
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.978 (Fisher's exact test), Q value = 1

Table S576.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TAS2R30 MUTATED 1 2 1 4 0
TAS2R30 WILD-TYPE 22 44 34 67 22
'KRTAP10-2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S577.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP10-2 MUTATED 2 1 4
KRTAP10-2 WILD-TYPE 47 78 64
'KRTAP10-2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S578.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP10-2 MUTATED 4 1 2
KRTAP10-2 WILD-TYPE 87 60 48
'KRTAP10-2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S579.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP10-2 MUTATED 0 1 1 2 3
KRTAP10-2 WILD-TYPE 36 30 57 33 34
'KRTAP10-2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S580.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP10-2 MUTATED 2 2 3
KRTAP10-2 WILD-TYPE 73 83 34
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S581.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP10-2 MUTATED 2 3 2
KRTAP10-2 WILD-TYPE 46 73 71
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0013 (Fisher's exact test), Q value = 1

Table S582.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP10-2 MUTATED 2 0 0 2 3
KRTAP10-2 WILD-TYPE 22 53 73 24 18

Figure S66.  Get High-res Image Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S583.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP10-2 MUTATED 3 0 1 3 0
KRTAP10-2 WILD-TYPE 23 34 39 57 37
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S584.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP10-2 MUTATED 2 0 1 2 2
KRTAP10-2 WILD-TYPE 21 46 34 69 20
'PPA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S585.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PPA2 MUTATED 0 2 2
PPA2 WILD-TYPE 49 77 66
'PPA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S586.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PPA2 MUTATED 3 1 0
PPA2 WILD-TYPE 88 60 50
'PPA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S587.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PPA2 MUTATED 0 0 2 1 1
PPA2 WILD-TYPE 36 31 56 34 36
'PPA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S588.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PPA2 MUTATED 1 2 1
PPA2 WILD-TYPE 74 83 36
'PPA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PPA2 MUTATED 1 2 1
PPA2 WILD-TYPE 47 74 72
'PPA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S590.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PPA2 MUTATED 0 2 1 0 1
PPA2 WILD-TYPE 24 51 72 26 20
'PPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 1

Table S591.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PPA2 MUTATED 1 0 0 3 0
PPA2 WILD-TYPE 25 34 40 57 37
'PPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S592.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PPA2 MUTATED 0 2 0 1 1
PPA2 WILD-TYPE 23 44 35 70 21
'SEPT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S593.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SEPT2 MUTATED 3 1 3
SEPT2 WILD-TYPE 46 78 65
'SEPT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S594.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SEPT2 MUTATED 5 2 0
SEPT2 WILD-TYPE 86 59 50
'SEPT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S595.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SEPT2 MUTATED 1 2 1 0 2
SEPT2 WILD-TYPE 35 29 57 35 35
'SEPT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S596.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SEPT2 MUTATED 3 1 2
SEPT2 WILD-TYPE 72 84 35
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S597.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SEPT2 MUTATED 1 4 2
SEPT2 WILD-TYPE 47 72 71
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S598.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SEPT2 MUTATED 1 1 2 2 1
SEPT2 WILD-TYPE 23 52 71 24 20
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S599.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SEPT2 MUTATED 0 2 1 2 2
SEPT2 WILD-TYPE 26 32 39 58 35
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S600.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SEPT2 MUTATED 0 1 3 2 1
SEPT2 WILD-TYPE 23 45 32 69 21
'DRD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S601.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
DRD3 MUTATED 2 1 2
DRD3 WILD-TYPE 47 78 66
'DRD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0726 (Fisher's exact test), Q value = 1

Table S602.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
DRD3 MUTATED 5 0 0
DRD3 WILD-TYPE 86 61 50
'DRD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0385 (Fisher's exact test), Q value = 1

Table S603.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
DRD3 MUTATED 0 3 1 0 0
DRD3 WILD-TYPE 36 28 57 35 37

Figure S67.  Get High-res Image Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'DRD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S604.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
DRD3 MUTATED 1 3 0
DRD3 WILD-TYPE 74 82 37
'DRD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00703 (Fisher's exact test), Q value = 1

Table S605.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
DRD3 MUTATED 4 0 1
DRD3 WILD-TYPE 44 76 72

Figure S68.  Get High-res Image Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DRD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S606.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
DRD3 MUTATED 2 1 1 1 0
DRD3 WILD-TYPE 22 52 72 25 21
'DRD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S607.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
DRD3 MUTATED 0 1 3 0 1
DRD3 WILD-TYPE 26 33 37 60 36
'DRD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S608.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
DRD3 MUTATED 2 1 1 1 0
DRD3 WILD-TYPE 21 45 34 70 22
'PSRC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S609.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PSRC1 MUTATED 2 1 1
PSRC1 WILD-TYPE 47 78 67
'PSRC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S610.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PSRC1 MUTATED 3 0 1
PSRC1 WILD-TYPE 88 61 49
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0418 (Fisher's exact test), Q value = 1

Table S611.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PSRC1 MUTATED 3 0 1
PSRC1 WILD-TYPE 45 76 72

Figure S69.  Get High-res Image Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'PSRC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S612.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PSRC1 MUTATED 1 1 1 1 0
PSRC1 WILD-TYPE 23 52 72 25 21
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S613.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PSRC1 MUTATED 0 1 2 0 1
PSRC1 WILD-TYPE 26 33 38 60 36
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S614.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PSRC1 MUTATED 1 1 1 1 0
PSRC1 WILD-TYPE 22 45 34 70 22
'KRTAP10-9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S615.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP10-9 MUTATED 1 2 0
KRTAP10-9 WILD-TYPE 48 77 68
'KRTAP10-9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S616.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP10-9 MUTATED 2 0 1
KRTAP10-9 WILD-TYPE 89 61 49
'KRTAP10-9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S617.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP10-9 MUTATED 0 0 1 0 2
KRTAP10-9 WILD-TYPE 36 31 57 35 35
'KRTAP10-9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 1

Table S618.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP10-9 MUTATED 0 1 2
KRTAP10-9 WILD-TYPE 75 84 35
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S619.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP10-9 MUTATED 1 1 1
KRTAP10-9 WILD-TYPE 47 75 72
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 1

Table S620.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP10-9 MUTATED 0 1 0 0 2
KRTAP10-9 WILD-TYPE 24 52 73 26 19

Figure S70.  Get High-res Image Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S621.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP10-9 MUTATED 1 0 0 2 0
KRTAP10-9 WILD-TYPE 25 34 40 58 37
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S622.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP10-9 MUTATED 0 1 0 1 1
KRTAP10-9 WILD-TYPE 23 45 35 70 21
'SPATA12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S623.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SPATA12 MUTATED 2 2 2
SPATA12 WILD-TYPE 47 77 66
'SPATA12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S624.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SPATA12 MUTATED 3 2 1
SPATA12 WILD-TYPE 88 59 49
'SPATA12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S625.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SPATA12 MUTATED 1 0 2 2 1
SPATA12 WILD-TYPE 35 31 56 33 36
'SPATA12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S626.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SPATA12 MUTATED 2 3 1
SPATA12 WILD-TYPE 73 82 36
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S627.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SPATA12 MUTATED 2 3 1
SPATA12 WILD-TYPE 46 73 72
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S628.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SPATA12 MUTATED 1 2 2 0 1
SPATA12 WILD-TYPE 23 51 71 26 20
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S629.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SPATA12 MUTATED 1 0 2 2 1
SPATA12 WILD-TYPE 25 34 38 58 36
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S630.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SPATA12 MUTATED 1 2 1 1 1
SPATA12 WILD-TYPE 22 44 34 70 21
'GPR112 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S631.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GPR112 MUTATED 5 4 5
GPR112 WILD-TYPE 44 75 63
'GPR112 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S632.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GPR112 MUTATED 9 4 2
GPR112 WILD-TYPE 82 57 48
'GPR112 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S633.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GPR112 MUTATED 1 4 3 3 3
GPR112 WILD-TYPE 35 27 55 32 34
'GPR112 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S634.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GPR112 MUTATED 7 4 3
GPR112 WILD-TYPE 68 81 34
'GPR112 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S635.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GPR112 MUTATED 3 8 4
GPR112 WILD-TYPE 45 68 69
'GPR112 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S636.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GPR112 MUTATED 0 4 7 1 3
GPR112 WILD-TYPE 24 49 66 25 18
'GPR112 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S637.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GPR112 MUTATED 0 1 2 7 5
GPR112 WILD-TYPE 26 33 38 53 32
'GPR112 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S638.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GPR112 MUTATED 0 5 4 3 3
GPR112 WILD-TYPE 23 41 31 68 19
'CLTCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S639.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CLTCL1 MUTATED 6 4 5
CLTCL1 WILD-TYPE 43 75 63
'CLTCL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S640.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CLTCL1 MUTATED 10 3 3
CLTCL1 WILD-TYPE 81 58 47
'CLTCL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S641.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CLTCL1 MUTATED 1 3 4 3 4
CLTCL1 WILD-TYPE 35 28 54 32 33
'CLTCL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S642.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CLTCL1 MUTATED 6 5 4
CLTCL1 WILD-TYPE 69 80 33
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S643.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CLTCL1 MUTATED 5 5 5
CLTCL1 WILD-TYPE 43 71 68
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0843 (Fisher's exact test), Q value = 1

Table S644.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CLTCL1 MUTATED 3 1 5 2 4
CLTCL1 WILD-TYPE 21 52 68 24 17
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S645.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CLTCL1 MUTATED 2 1 4 5 3
CLTCL1 WILD-TYPE 24 33 36 55 34
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S646.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CLTCL1 MUTATED 3 1 3 5 3
CLTCL1 WILD-TYPE 20 45 32 66 19
'OR2A14 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S647.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2A14 MUTATED 2 1 2
OR2A14 WILD-TYPE 47 78 66
'OR2A14 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S648.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2A14 MUTATED 4 0 1
OR2A14 WILD-TYPE 87 61 49
'OR2A14 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S649.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2A14 MUTATED 0 0 2 1 1
OR2A14 WILD-TYPE 36 31 56 34 36
'OR2A14 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S650.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2A14 MUTATED 1 2 1
OR2A14 WILD-TYPE 74 83 36
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S651.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2A14 MUTATED 1 2 2
OR2A14 WILD-TYPE 47 74 71
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S652.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2A14 MUTATED 1 0 3 0 1
OR2A14 WILD-TYPE 23 53 70 26 20
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S653.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2A14 MUTATED 0 2 1 2 0
OR2A14 WILD-TYPE 26 32 39 58 37
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S654.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2A14 MUTATED 1 0 1 2 1
OR2A14 WILD-TYPE 22 46 34 69 21
'OR4C16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0925 (Fisher's exact test), Q value = 1

Table S655.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR4C16 MUTATED 3 4 0
OR4C16 WILD-TYPE 46 75 68
'OR4C16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S656.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR4C16 MUTATED 4 0 3
OR4C16 WILD-TYPE 87 61 47
'OR4C16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0197 (Fisher's exact test), Q value = 1

Table S657.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR4C16 MUTATED 1 2 0 0 4
OR4C16 WILD-TYPE 35 29 58 35 33

Figure S71.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'OR4C16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0336 (Fisher's exact test), Q value = 1

Table S658.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR4C16 MUTATED 2 1 4
OR4C16 WILD-TYPE 73 84 33

Figure S72.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'OR4C16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S659.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR4C16 MUTATED 2 3 2
OR4C16 WILD-TYPE 46 73 71
'OR4C16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00339 (Fisher's exact test), Q value = 1

Table S660.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR4C16 MUTATED 1 0 1 1 4
OR4C16 WILD-TYPE 23 53 72 25 17

Figure S73.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'OR4C16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S661.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR4C16 MUTATED 1 0 1 3 2
OR4C16 WILD-TYPE 25 34 39 57 35
'OR4C16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0788 (Fisher's exact test), Q value = 1

Table S662.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR4C16 MUTATED 1 0 1 2 3
OR4C16 WILD-TYPE 22 46 34 69 19
'GBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S663.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GBP1 MUTATED 0 4 4
GBP1 WILD-TYPE 49 75 64
'GBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S664.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GBP1 MUTATED 3 2 3
GBP1 WILD-TYPE 88 59 47
'GBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S665.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GBP1 MUTATED 1 1 2 1 3
GBP1 WILD-TYPE 35 30 56 34 34
'GBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S666.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GBP1 MUTATED 2 3 3
GBP1 WILD-TYPE 73 82 34
'GBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S667.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GBP1 MUTATED 1 3 4
GBP1 WILD-TYPE 47 73 69
'GBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S668.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GBP1 MUTATED 2 3 2 0 1
GBP1 WILD-TYPE 22 50 71 26 20
'GBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S669.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GBP1 MUTATED 2 1 1 2 2
GBP1 WILD-TYPE 24 33 39 58 35
'GBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S670.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GBP1 MUTATED 2 2 2 2 0
GBP1 WILD-TYPE 21 44 33 69 22
'OR6B3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S671.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR6B3 MUTATED 2 2 1
OR6B3 WILD-TYPE 47 77 67
'OR6B3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S672.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR6B3 MUTATED 3 1 1
OR6B3 WILD-TYPE 88 60 49
'OR6B3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S673.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR6B3 MUTATED 0 1 1 1 2
OR6B3 WILD-TYPE 36 30 57 34 35
'OR6B3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S674.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR6B3 MUTATED 1 2 2
OR6B3 WILD-TYPE 74 83 35
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S675.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR6B3 MUTATED 1 4 0
OR6B3 WILD-TYPE 47 72 73
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S676.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR6B3 MUTATED 1 1 1 0 2
OR6B3 WILD-TYPE 23 52 72 26 19
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S677.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR6B3 MUTATED 0 0 1 3 1
OR6B3 WILD-TYPE 26 34 39 57 36
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0763 (Fisher's exact test), Q value = 1

Table S678.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR6B3 MUTATED 1 1 1 0 2
OR6B3 WILD-TYPE 22 45 34 71 20
'OR2T27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S679.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2T27 MUTATED 3 3 4
OR2T27 WILD-TYPE 46 76 64
'OR2T27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S680.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2T27 MUTATED 9 1 0
OR2T27 WILD-TYPE 82 60 50

Figure S74.  Get High-res Image Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'OR2T27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S681.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2T27 MUTATED 0 3 2 1 3
OR2T27 WILD-TYPE 36 28 56 34 34
'OR2T27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S682.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2T27 MUTATED 3 3 3
OR2T27 WILD-TYPE 72 82 34
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S683.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2T27 MUTATED 2 6 2
OR2T27 WILD-TYPE 46 70 71
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S684.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2T27 MUTATED 0 3 2 2 3
OR2T27 WILD-TYPE 24 50 71 24 18
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S685.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2T27 MUTATED 1 1 1 6 1
OR2T27 WILD-TYPE 25 33 39 54 36
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S686.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2T27 MUTATED 0 3 2 2 3
OR2T27 WILD-TYPE 23 43 33 69 19
'RAET1E MUTATION STATUS' versus 'CN_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S687.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RAET1E MUTATED 1 3 1
RAET1E WILD-TYPE 48 76 67
'RAET1E MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S688.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RAET1E MUTATED 3 0 2
RAET1E WILD-TYPE 88 61 48
'RAET1E MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S689.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RAET1E MUTATED 0 1 1 0 3
RAET1E WILD-TYPE 36 30 57 35 34
'RAET1E MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0332 (Fisher's exact test), Q value = 1

Table S690.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RAET1E MUTATED 0 2 3
RAET1E WILD-TYPE 75 83 34

Figure S75.  Get High-res Image Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RAET1E MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S691.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RAET1E MUTATED 2 2 1
RAET1E WILD-TYPE 46 74 72
'RAET1E MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0187 (Fisher's exact test), Q value = 1

Table S692.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RAET1E MUTATED 2 1 0 0 2
RAET1E WILD-TYPE 22 52 73 26 19

Figure S76.  Get High-res Image Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'RAET1E MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S693.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RAET1E MUTATED 1 0 2 2 0
RAET1E WILD-TYPE 25 34 38 58 37
'RAET1E MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S694.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RAET1E MUTATED 2 1 0 1 1
RAET1E WILD-TYPE 21 45 35 70 21
'SHROOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S695.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SHROOM1 MUTATED 2 1 2
SHROOM1 WILD-TYPE 47 78 66
'SHROOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S696.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SHROOM1 MUTATED 3 1 1
SHROOM1 WILD-TYPE 88 60 49
'SHROOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S697.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SHROOM1 MUTATED 1 1 1 1 1
SHROOM1 WILD-TYPE 35 30 57 34 36
'SHROOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S698.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SHROOM1 MUTATED 2 2 1
SHROOM1 WILD-TYPE 73 83 36
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S699.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SHROOM1 MUTATED 1 2 2
SHROOM1 WILD-TYPE 47 74 71
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 1

Table S700.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SHROOM1 MUTATED 2 1 1 0 1
SHROOM1 WILD-TYPE 22 52 72 26 20
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S701.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SHROOM1 MUTATED 1 1 1 2 0
SHROOM1 WILD-TYPE 25 33 39 58 37
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0773 (Fisher's exact test), Q value = 1

Table S702.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SHROOM1 MUTATED 2 1 1 0 1
SHROOM1 WILD-TYPE 21 45 34 71 21
'OR52I2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S703.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR52I2 MUTATED 1 2 3
OR52I2 WILD-TYPE 48 77 65
'OR52I2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S704.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR52I2 MUTATED 3 2 1
OR52I2 WILD-TYPE 88 59 49
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S705.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR52I2 MUTATED 0 1 1 1 3
OR52I2 WILD-TYPE 36 30 57 34 34
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S706.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR52I2 MUTATED 1 2 3
OR52I2 WILD-TYPE 74 83 34
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S707.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR52I2 MUTATED 2 2 2
OR52I2 WILD-TYPE 46 74 71
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.048 (Fisher's exact test), Q value = 1

Table S708.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR52I2 MUTATED 1 1 1 0 3
OR52I2 WILD-TYPE 23 52 72 26 18

Figure S77.  Get High-res Image Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S709.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR52I2 MUTATED 2 0 1 3 0
OR52I2 WILD-TYPE 24 34 39 57 37
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S710.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR52I2 MUTATED 1 1 0 2 2
OR52I2 WILD-TYPE 22 45 35 69 20
'OR13C2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S711.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR13C2 MUTATED 2 0 2
OR13C2 WILD-TYPE 47 79 66
'OR13C2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S712.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR13C2 MUTATED 1 3 0
OR13C2 WILD-TYPE 90 58 50
'OR13C2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0849 (Fisher's exact test), Q value = 1

Table S713.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR13C2 MUTATED 0 0 0 2 2
OR13C2 WILD-TYPE 36 31 58 33 35
'OR13C2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S714.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR13C2 MUTATED 2 0 2
OR13C2 WILD-TYPE 73 85 35
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S715.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR13C2 MUTATED 0 3 1
OR13C2 WILD-TYPE 48 73 72
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S716.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR13C2 MUTATED 0 0 2 0 2
OR13C2 WILD-TYPE 24 53 71 26 19
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S717.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR13C2 MUTATED 1 0 0 2 1
OR13C2 WILD-TYPE 25 34 40 58 36
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S718.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR13C2 MUTATED 0 0 1 1 2
OR13C2 WILD-TYPE 23 46 34 70 20
'LIPC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S719.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LIPC MUTATED 2 2 2
LIPC WILD-TYPE 47 77 66
'LIPC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S720.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LIPC MUTATED 3 2 1
LIPC WILD-TYPE 88 59 49
'LIPC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S721.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LIPC MUTATED 0 0 3 3 0
LIPC WILD-TYPE 36 31 55 32 37
'LIPC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S722.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LIPC MUTATED 3 3 0
LIPC WILD-TYPE 72 82 37
'LIPC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 1

Table S723.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LIPC MUTATED 0 4 2
LIPC WILD-TYPE 48 72 71
'LIPC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.969 (Fisher's exact test), Q value = 1

Table S724.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LIPC MUTATED 0 2 3 1 0
LIPC WILD-TYPE 24 51 70 25 21
'LIPC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S725.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LIPC MUTATED 1 0 0 4 1
LIPC WILD-TYPE 25 34 40 56 36
'LIPC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S726.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LIPC MUTATED 0 2 1 3 0
LIPC WILD-TYPE 23 44 34 68 22
'FAM22F MUTATION STATUS' versus 'CN_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S727.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FAM22F MUTATED 2 0 2
FAM22F WILD-TYPE 47 79 66
'FAM22F MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 1

Table S728.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FAM22F MUTATED 0 4 0
FAM22F WILD-TYPE 91 57 50

Figure S78.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'FAM22F MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0342 (Fisher's exact test), Q value = 1

Table S729.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FAM22F MUTATED 3 0 0 1 0
FAM22F WILD-TYPE 33 31 58 34 37

Figure S79.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'FAM22F MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0413 (Fisher's exact test), Q value = 1

Table S730.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FAM22F MUTATED 4 0 0
FAM22F WILD-TYPE 71 85 37

Figure S80.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'FAM22F MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S731.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FAM22F MUTATED 1 0 3
FAM22F WILD-TYPE 47 76 70
'FAM22F MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S732.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FAM22F MUTATED 0 1 3 0 0
FAM22F WILD-TYPE 24 52 70 26 21
'FAM22F MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00101 (Fisher's exact test), Q value = 0.8

Table S733.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FAM22F MUTATED 0 4 0 0 0
FAM22F WILD-TYPE 26 30 40 60 37

Figure S81.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'FAM22F MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S734.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FAM22F MUTATED 0 0 0 4 0
FAM22F WILD-TYPE 23 46 35 67 22
'GLRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S735.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GLRX3 MUTATED 1 3 0
GLRX3 WILD-TYPE 48 76 68
'GLRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S736.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GLRX3 MUTATED 3 0 1
GLRX3 WILD-TYPE 88 61 49
'GLRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S737.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GLRX3 MUTATED 0 0 1 0 3
GLRX3 WILD-TYPE 36 31 57 35 34
'GLRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0213 (Fisher's exact test), Q value = 1

Table S738.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GLRX3 MUTATED 0 1 3
GLRX3 WILD-TYPE 75 84 34

Figure S82.  Get High-res Image Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'GLRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S739.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GLRX3 MUTATED 0 3 1
GLRX3 WILD-TYPE 48 73 72
'GLRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00792 (Fisher's exact test), Q value = 1

Table S740.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GLRX3 MUTATED 0 1 0 0 3
GLRX3 WILD-TYPE 24 52 73 26 18

Figure S83.  Get High-res Image Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'GLRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S741.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GLRX3 MUTATED 1 0 0 3 0
GLRX3 WILD-TYPE 25 34 40 57 37
'GLRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S742.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GLRX3 MUTATED 0 1 0 1 2
GLRX3 WILD-TYPE 23 45 35 70 20
'HOXA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S743.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HOXA4 MUTATED 1 3 1
HOXA4 WILD-TYPE 48 76 67
'HOXA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S744.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HOXA4 MUTATED 4 1 0
HOXA4 WILD-TYPE 87 60 50
'HOXA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S745.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HOXA4 MUTATED 1 1 2 0 1
HOXA4 WILD-TYPE 35 30 56 35 36
'HOXA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S746.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HOXA4 MUTATED 1 3 1
HOXA4 WILD-TYPE 74 82 36
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S747.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HOXA4 MUTATED 3 1 1
HOXA4 WILD-TYPE 45 75 72
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0847 (Fisher's exact test), Q value = 1

Table S748.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HOXA4 MUTATED 2 2 0 0 1
HOXA4 WILD-TYPE 22 51 73 26 20
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S749.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HOXA4 MUTATED 0 2 2 1 0
HOXA4 WILD-TYPE 26 32 38 59 37
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S750.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HOXA4 MUTATED 2 1 0 1 1
HOXA4 WILD-TYPE 21 45 35 70 21
'DENND4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S751.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
DENND4B MUTATED 2 2 5
DENND4B WILD-TYPE 47 77 63
'DENND4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 1

Table S752.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
DENND4B MUTATED 7 1 1
DENND4B WILD-TYPE 84 60 49
'DENND4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0519 (Fisher's exact test), Q value = 1

Table S753.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
DENND4B MUTATED 0 4 3 1 0
DENND4B WILD-TYPE 36 27 55 34 37
'DENND4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S754.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
DENND4B MUTATED 2 6 0
DENND4B WILD-TYPE 73 79 37
'DENND4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S755.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
DENND4B MUTATED 4 3 2
DENND4B WILD-TYPE 44 73 71
'DENND4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S756.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
DENND4B MUTATED 3 1 4 0 1
DENND4B WILD-TYPE 21 52 69 26 20
'DENND4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S757.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
DENND4B MUTATED 0 1 4 3 1
DENND4B WILD-TYPE 26 33 36 57 36
'DENND4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S758.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
DENND4B MUTATED 3 1 1 3 1
DENND4B WILD-TYPE 20 45 34 68 21
'ESX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S759.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ESX1 MUTATED 2 2 2
ESX1 WILD-TYPE 47 77 66
'ESX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S760.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ESX1 MUTATED 4 1 1
ESX1 WILD-TYPE 87 60 49
'ESX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S761.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ESX1 MUTATED 1 3 2 0 0
ESX1 WILD-TYPE 35 28 56 35 37
'ESX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S762.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ESX1 MUTATED 1 5 0
ESX1 WILD-TYPE 74 80 37
'ESX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S763.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ESX1 MUTATED 1 2 3
ESX1 WILD-TYPE 47 74 70
'ESX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S764.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ESX1 MUTATED 1 4 1 0 0
ESX1 WILD-TYPE 23 49 72 26 21
'ESX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S765.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ESX1 MUTATED 0 1 3 0 2
ESX1 WILD-TYPE 26 33 37 60 35
'ESX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 1

Table S766.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ESX1 MUTATED 1 4 0 1 0
ESX1 WILD-TYPE 22 42 35 70 22
'SLFN12L MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S767.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SLFN12L MUTATED 1 3 2
SLFN12L WILD-TYPE 48 76 66
'SLFN12L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 1

Table S768.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SLFN12L MUTATED 4 0 2
SLFN12L WILD-TYPE 87 61 48
'SLFN12L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S769.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SLFN12L MUTATED 2 1 2 0 0
SLFN12L WILD-TYPE 34 30 56 35 37
'SLFN12L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S770.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SLFN12L MUTATED 2 3 0
SLFN12L WILD-TYPE 73 82 37
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S771.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SLFN12L MUTATED 1 2 3
SLFN12L WILD-TYPE 47 74 70
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S772.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SLFN12L MUTATED 0 1 3 1 1
SLFN12L WILD-TYPE 24 52 70 25 20
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S773.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SLFN12L MUTATED 0 2 0 2 2
SLFN12L WILD-TYPE 26 32 40 58 35
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S774.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SLFN12L MUTATED 0 1 1 3 1
SLFN12L WILD-TYPE 23 45 34 68 21
'FKBP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S775.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FKBP4 MUTATED 1 1 3
FKBP4 WILD-TYPE 48 78 65
'FKBP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S776.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FKBP4 MUTATED 4 1 0
FKBP4 WILD-TYPE 87 60 50
'FKBP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S777.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FKBP4 MUTATED 0 2 1 0 1
FKBP4 WILD-TYPE 36 29 57 35 36
'FKBP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 1

Table S778.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FKBP4 MUTATED 0 3 1
FKBP4 WILD-TYPE 75 82 36
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S779.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FKBP4 MUTATED 1 3 1
FKBP4 WILD-TYPE 47 73 72
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S780.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FKBP4 MUTATED 1 2 1 0 1
FKBP4 WILD-TYPE 23 51 72 26 20
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S781.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FKBP4 MUTATED 0 1 3 1 0
FKBP4 WILD-TYPE 26 33 37 59 37
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S782.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FKBP4 MUTATED 1 2 0 1 1
FKBP4 WILD-TYPE 22 44 35 70 21
'AQP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S783.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AQP7 MUTATED 2 3 4
AQP7 WILD-TYPE 47 76 64
'AQP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0226 (Fisher's exact test), Q value = 1

Table S784.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AQP7 MUTATED 8 1 0
AQP7 WILD-TYPE 83 60 50

Figure S84.  Get High-res Image Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'AQP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S785.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AQP7 MUTATED 0 0 5 1 3
AQP7 WILD-TYPE 36 31 53 34 34
'AQP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S786.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AQP7 MUTATED 2 4 3
AQP7 WILD-TYPE 73 81 34
'AQP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S787.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AQP7 MUTATED 0 5 2
AQP7 WILD-TYPE 48 71 71
'AQP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S788.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AQP7 MUTATED 1 3 1 0 2
AQP7 WILD-TYPE 23 50 72 26 19
'AQP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S789.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AQP7 MUTATED 1 1 1 4 0
AQP7 WILD-TYPE 25 33 39 56 37
'AQP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S790.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AQP7 MUTATED 1 3 0 1 2
AQP7 WILD-TYPE 22 43 35 70 20
'MAP4K5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S791.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MAP4K5 MUTATED 1 6 3
MAP4K5 WILD-TYPE 48 73 65
'MAP4K5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S792.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MAP4K5 MUTATED 4 3 3
MAP4K5 WILD-TYPE 87 58 47
'MAP4K5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S793.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MAP4K5 MUTATED 2 3 1 2 2
MAP4K5 WILD-TYPE 34 28 57 33 35
'MAP4K5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S794.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MAP4K5 MUTATED 4 4 2
MAP4K5 WILD-TYPE 71 81 35
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S795.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MAP4K5 MUTATED 2 4 4
MAP4K5 WILD-TYPE 46 72 69
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.373 (Fisher's exact test), Q value = 1

Table S796.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MAP4K5 MUTATED 2 1 3 2 2
MAP4K5 WILD-TYPE 22 52 70 24 19
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.607 (Fisher's exact test), Q value = 1

Table S797.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MAP4K5 MUTATED 3 1 2 2 2
MAP4K5 WILD-TYPE 23 33 38 58 35
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S798.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MAP4K5 MUTATED 2 1 1 5 1
MAP4K5 WILD-TYPE 21 45 34 66 21
'BCL11A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S799.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BCL11A MUTATED 2 2 3
BCL11A WILD-TYPE 47 77 65
'BCL11A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S800.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BCL11A MUTATED 3 1 3
BCL11A WILD-TYPE 88 60 47
'BCL11A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S801.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BCL11A MUTATED 2 1 2 0 1
BCL11A WILD-TYPE 34 30 56 35 36
'BCL11A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0733 (Fisher's exact test), Q value = 1

Table S802.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BCL11A MUTATED 0 5 1
BCL11A WILD-TYPE 75 80 36
'BCL11A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00489 (Fisher's exact test), Q value = 1

Table S803.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BCL11A MUTATED 5 0 2
BCL11A WILD-TYPE 43 76 71

Figure S85.  Get High-res Image Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'BCL11A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S804.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BCL11A MUTATED 3 2 2 0 0
BCL11A WILD-TYPE 21 51 71 26 21
'BCL11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S805.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BCL11A MUTATED 1 2 3 1 0
BCL11A WILD-TYPE 25 32 37 59 37
'BCL11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S806.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BCL11A MUTATED 3 1 0 3 0
BCL11A WILD-TYPE 20 45 35 68 22
Methods & Data
Input

  • Mutation data file = transformed.cor.cli.txt

  • Molecular subtypes file = LIHC-TP.transferedmergedcluster.txt

  • Number of patients = 202

  • Number of significantly mutated genes = 101

  • Number of Molecular subtypes = 8

  • Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References
[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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