Correlation between copy number variation genes (focal events) and selected clinical features
Colorectal Adenocarcinoma (Primary solid tumor)
02 April 2015  |  analyses__2015_04_02
Maintainer Information
Citation Information
doi:10.7908/C17H1HM2
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between copy number variation genes (focal events) and selected clinical features. Broad Institute of MIT and Harvard. doi:10.7908/C17H1HM2
Overview
Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 73 focal events and 13 clinical features across 608 patients, 388 significant findings detected with Q value < 0.25.

  • amp_1q31.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_2q33.1 cnv correlated to 'Time to Death',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_5p12 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_5q22.3 cnv correlated to 'PATHOLOGY_M_STAGE' and 'COMPLETENESS_OF_RESECTION'.

  • amp_6p21.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_7p21.3 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_8p11.23 cnv correlated to 'COMPLETENESS_OF_RESECTION'.

  • amp_8p11.21 cnv correlated to 'PATHOLOGY_M_STAGE' and 'COMPLETENESS_OF_RESECTION'.

  • amp_8q12.1 cnv correlated to 'YEARS_TO_BIRTH',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_8q24.21 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'RADIATIONS_RADIATION_REGIMENINDICATION'.

  • amp_10q22.3 cnv correlated to 'PATHOLOGY_N_STAGE' and 'NUMBER_OF_LYMPH_NODES'.

  • amp_11p15.5 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE', and 'HISTOLOGICAL_TYPE'.

  • amp_12p13.32 cnv correlated to 'NEOPLASM_DISEASESTAGE' and 'PATHOLOGY_N_STAGE'.

  • amp_13q12.13 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • amp_13q12.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • amp_13q22.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • amp_15q26.1 cnv correlated to 'PATHOLOGY_N_STAGE' and 'NUMBER_OF_LYMPH_NODES'.

  • amp_16p11.2 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_17q12 cnv correlated to 'Time to Death',  'PATHOLOGY_M_STAGE', and 'COMPLETENESS_OF_RESECTION'.

  • amp_17q24.1 cnv correlated to 'Time to Death',  'PATHOLOGY_M_STAGE', and 'HISTOLOGICAL_TYPE'.

  • amp_19p13.2 cnv correlated to 'HISTOLOGICAL_TYPE'.

  • amp_19q12 cnv correlated to 'PATHOLOGY_M_STAGE' and 'HISTOLOGICAL_TYPE'.

  • amp_20p12.1 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'GENDER',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'COMPLETENESS_OF_RESECTION'.

  • amp_20p11.21 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_M_STAGE',  'GENDER', and 'HISTOLOGICAL_TYPE'.

  • amp_20q11.21 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_20q12 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • amp_20q13.31 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_1p36.11 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_1p33 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_1p13.2 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_2p12 cnv correlated to 'PRIMARY_SITE_OF_DISEASE' and 'HISTOLOGICAL_TYPE'.

  • del_2q22.1 cnv correlated to 'RACE'.

  • del_3p26.3 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_3p14.2 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_M_STAGE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_3q26.31 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_M_STAGE', and 'HISTOLOGICAL_TYPE'.

  • del_4p16.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_4q22.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_4q35.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_5q12.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_5q21.2 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_5q22.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_6p25.3 cnv correlated to 'YEARS_TO_BIRTH',  'GENDER', and 'RACE'.

  • del_6q26 cnv correlated to 'Time to Death',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • del_8p23.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'GENDER',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_8p22 cnv correlated to 'Time to Death',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_8q11.1 cnv correlated to 'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • del_9p24.2 cnv correlated to 'PATHOLOGY_M_STAGE',  'GENDER', and 'NUMBER_OF_LYMPH_NODES'.

  • del_10p15.3 cnv correlated to 'YEARS_TO_BIRTH',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_10q21.1 cnv correlated to 'YEARS_TO_BIRTH',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_10q23.31 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_10q25.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_11q22.3 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_12p13.1 cnv correlated to 'Time to Death',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE', and 'HISTOLOGICAL_TYPE'.

  • del_12q21.33 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_14q11.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE', and 'HISTOLOGICAL_TYPE'.

  • del_14q31.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_15q11.2 cnv correlated to 'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_15q15.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_15q21.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_15q22.33 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'NUMBER_OF_LYMPH_NODES', and 'RACE'.

  • del_16p13.3 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE', and 'PATHOLOGY_T_STAGE'.

  • del_16q23.1 cnv correlated to 'Time to Death'.

  • del_17p12 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_17q24.3 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_18p11.31 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_18q12.2 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_18q21.2 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'GENDER',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_18q22.1 cnv correlated to 'YEARS_TO_BIRTH',  'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'GENDER',  'HISTOLOGICAL_TYPE',  'RADIATIONS_RADIATION_REGIMENINDICATION',  'COMPLETENESS_OF_RESECTION', and 'NUMBER_OF_LYMPH_NODES'.

  • del_19p13.3 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_20p12.1 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_21q11.2 cnv correlated to 'PRIMARY_SITE_OF_DISEASE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

  • del_22q13.32 cnv correlated to 'Time to Death',  'NEOPLASM_DISEASESTAGE',  'PATHOLOGY_N_STAGE',  'PATHOLOGY_M_STAGE',  'HISTOLOGICAL_TYPE', and 'NUMBER_OF_LYMPH_NODES'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 73 focal events and 13 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 388 significant findings detected.

Clinical
Features 		Time
to
Death 		YEARS
TO
BIRTH 		PRIMARY
SITE
OF
DISEASE 		NEOPLASM
DISEASESTAGE 		PATHOLOGY
T
STAGE 		PATHOLOGY
N
STAGE 		PATHOLOGY
M
STAGE 		GENDER HISTOLOGICAL
TYPE 		RADIATIONS
RADIATION
REGIMENINDICATION 		COMPLETENESS
OF
RESECTION 		NUMBER
OF
LYMPH
NODES 		RACE
nCNV (%) nWild-Type logrank test Wilcoxon-test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Wilcoxon-test Fisher's exact test
del 8p23 2 286 (47%) 322 0.415
(0.623) 		0.194
(0.392) 		7.19e-05
(0.0012) 		0.00012
(0.00184) 		0.0742
(0.209) 		1e-05
(0.000256) 		0.000154
(0.00219) 		0.0283
(0.109) 		1e-05
(0.000256) 		0.0912
(0.232) 		0.00979
(0.0547) 		5.45e-06
(0.000256) 		0.549
(0.735)
del 8p22 299 (49%) 309 0.0943
(0.237) 		0.216
(0.42) 		0.000917
(0.00837) 		1e-05
(0.000256) 		0.0274
(0.107) 		1e-05
(0.000256) 		5.51e-05
(0.00103) 		0.123
(0.285) 		0.00018
(0.00244) 		0.102
(0.249) 		0.0061
(0.0375) 		1.06e-07
(3.35e-05) 		0.25
(0.467)
del 18q21 2 427 (70%) 181 0.547
(0.735) 		0.0336
(0.12) 		3.47e-09
(1.65e-06) 		3e-05
(0.000694) 		0.313
(0.53) 		1e-05
(0.000256) 		3.68e-06
(0.000256) 		0.0913
(0.232) 		1e-05
(0.000256) 		0.064
(0.189) 		0.0413
(0.137) 		2.75e-06
(0.000256) 		0.647
(0.808)
del 18q22 1 422 (69%) 186 0.647
(0.808) 		0.0915
(0.232) 		1.63e-07
(3.86e-05) 		1e-05
(0.000256) 		0.436
(0.645) 		1e-05
(0.000256) 		8.34e-06
(0.000256) 		0.095
(0.237) 		1e-05
(0.000256) 		0.0633
(0.188) 		0.0826
(0.222) 		2.47e-05
(6e-04) 		0.339
(0.554)
del 15q22 33 234 (38%) 374 0.656
(0.811) 		0.293
(0.509) 		0.018
(0.0809) 		0.00597
(0.037) 		0.0928
(0.233) 		0.00175
(0.0142) 		0.00509
(0.0329) 		0.405
(0.616) 		0.0128
(0.0628) 		0.00267
(0.0201) 		0.575
(0.753) 		0.000523
(0.00551) 		0.0858
(0.228)
del 18q12 2 410 (67%) 198 0.512
(0.705) 		0.0225
(0.0943) 		1.39e-09
(1.32e-06) 		0.00023
(0.00287) 		0.359
(0.571) 		0.00013
(0.00193) 		0.000216
(0.00273) 		0.26
(0.474) 		1e-05
(0.000256) 		0.0348
(0.122) 		0.0446
(0.145) 		0.000286
(0.00348) 		0.351
(0.563)
amp 7p21 3 359 (59%) 249 0.58
(0.759) 		0.066
(0.193) 		0.0249
(0.0999) 		6e-05
(0.00107) 		0.934
(0.966) 		1e-05
(0.000256) 		0.0119
(0.0602) 		0.934
(0.966) 		0.00073
(0.00679) 		0.0897
(0.231) 		0.29
(0.506) 		5.17e-05
(0.001) 		0.653
(0.809)
amp 8q12 1 326 (54%) 282 0.729
(0.847) 		0.0951
(0.237) 		0.312
(0.53) 		0.0531
(0.164) 		0.304
(0.522) 		0.101
(0.249) 		0.00919
(0.0525) 		0.415
(0.623) 		0.0226
(0.0943) 		0.0421
(0.139) 		0.0863
(0.228) 		0.0884
(0.231) 		0.411
(0.62)
amp 13q12 13 396 (65%) 212 0.671
(0.818) 		0.43
(0.639) 		0.000528
(0.00551) 		2e-05
(0.000499) 		0.743
(0.854) 		4e-05
(0.000825) 		0.00127
(0.0112) 		0.609
(0.782) 		1e-05
(0.000256) 		0.507
(0.702) 		0.0459
(0.148) 		5.52e-05
(0.00103) 		0.0188
(0.0836)
amp 13q12 2 391 (64%) 217 0.821
(0.896) 		0.379
(0.591) 		0.000543
(0.00554) 		7e-05
(0.00119) 		0.812
(0.891) 		3e-05
(0.000694) 		0.00452
(0.0294) 		0.445
(0.652) 		1e-05
(0.000256) 		0.502
(0.699) 		0.0833
(0.223) 		6.93e-05
(0.00119) 		0.0266
(0.104)
del 1p36 11 240 (39%) 368 0.125
(0.287) 		0.0502
(0.158) 		0.0903
(0.231) 		0.00349
(0.0245) 		0.246
(0.462) 		0.00228
(0.0177) 		3.54e-05
(0.000782) 		0.158
(0.339) 		0.00168
(0.0138) 		0.744
(0.854) 		0.0844
(0.225) 		0.000369
(0.00421) 		0.303
(0.521)
del 3p26 3 90 (15%) 518 0.0479
(0.152) 		0.462
(0.664) 		0.435
(0.645) 		0.03
(0.113) 		0.0821
(0.222) 		0.0109
(0.0586) 		0.000707
(0.00664) 		0.648
(0.808) 		0.0589
(0.179) 		0.628
(0.797) 		0.0636
(0.188) 		0.00536
(0.0341) 		0.541
(0.728)
del 4p16 2 196 (32%) 412 0.176
(0.366) 		0.942
(0.971) 		0.0614
(0.184) 		0.00267
(0.0201) 		0.773
(0.866) 		0.00013
(0.00193) 		0.000363
(0.0042) 		0.165
(0.349) 		0.0313
(0.117) 		3.31e-05
(0.000748) 		0.0906
(0.231) 		7.59e-05
(0.00124) 		0.387
(0.598)
del 18p11 31 365 (60%) 243 0.376
(0.589) 		0.0134
(0.0646) 		2.47e-06
(0.000256) 		0.00017
(0.00234) 		0.884
(0.939) 		0.00669
(0.0407) 		3.51e-06
(0.000256) 		0.679
(0.823) 		1e-05
(0.000256) 		0.328
(0.544) 		0.0202
(0.087) 		0.0116
(0.0598) 		0.841
(0.912)
amp 6p21 1 154 (25%) 454 0.663
(0.812) 		0.772
(0.866) 		0.0336
(0.12) 		0.012
(0.0606) 		0.27
(0.486) 		0.00014
(0.00204) 		0.0137
(0.0651) 		0.191
(0.388) 		0.00758
(0.0447) 		0.00134
(0.0116) 		0.115
(0.272) 		0.000207
(0.00269) 		0.181
(0.374)
amp 13q22 1 394 (65%) 214 0.715
(0.84) 		0.645
(0.807) 		0.021
(0.0898) 		0.00054
(0.00554) 		0.709
(0.84) 		6e-05
(0.00107) 		0.00965
(0.0542) 		0.174
(0.364) 		1e-05
(0.000256) 		0.505
(0.701) 		0.254
(0.469) 		0.000321
(0.00386) 		0.0952
(0.237)
amp 20p12 1 277 (46%) 331 0.333
(0.549) 		0.598
(0.775) 		0.168
(0.354) 		0.00375
(0.0256) 		0.898
(0.946) 		0.089
(0.231) 		0.000343
(0.00402) 		0.0339
(0.12) 		0.0115
(0.0598) 		0.0869
(0.228) 		0.0726
(0.206) 		0.118
(0.278) 		0.83
(0.903)
amp 20q11 21 463 (76%) 145 0.866
(0.928) 		0.596
(0.774) 		4.73e-06
(0.000256) 		0.00064
(0.00613) 		0.27
(0.485) 		0.00055
(0.00555) 		0.00344
(0.0245) 		0.295
(0.509) 		1e-05
(0.000256) 		0.694
(0.833) 		0.0401
(0.134) 		0.00271
(0.0203) 		0.319
(0.536)
amp 20q12 465 (76%) 143 0.998
(1.00) 		0.502
(0.699) 		2.44e-06
(0.000256) 		0.00024
(0.00296) 		0.359
(0.571) 		0.00043
(0.0048) 		0.000445
(0.00485) 		0.293
(0.509) 		1e-05
(0.000256) 		0.693
(0.833) 		0.0393
(0.132) 		0.00283
(0.021) 		0.213
(0.418)
amp 20q13 31 468 (77%) 140 0.96
(0.987) 		0.533
(0.725) 		3.78e-06
(0.000256) 		0.00044
(0.00485) 		0.228
(0.436) 		0.00034
(0.00402) 		0.0007
(0.00664) 		0.441
(0.65) 		1e-05
(0.000256) 		0.692
(0.833) 		0.0385
(0.13) 		0.00257
(0.0197) 		0.213
(0.418)
del 4q35 1 227 (37%) 381 0.962
(0.987) 		0.116
(0.273) 		0.0871
(0.228) 		0.0457
(0.147) 		0.588
(0.767) 		0.00057
(0.00569) 		0.068
(0.197) 		1
(1.00) 		0.0593
(0.18) 		0.00212
(0.0166) 		0.769
(0.863) 		0.000164
(0.00229) 		0.397
(0.61)
del 5q12 1 156 (26%) 452 0.266
(0.481) 		0.154
(0.334) 		0.0212
(0.0898) 		0.0376
(0.128) 		0.987
(1.00) 		0.0225
(0.0943) 		0.0137
(0.0651) 		0.71
(0.84) 		0.0104
(0.0565) 		0.000115
(0.00179) 		0.658
(0.812) 		0.0113
(0.0598) 		0.337
(0.552)
del 5q22 2 186 (31%) 422 0.146
(0.322) 		0.421
(0.628) 		0.074
(0.209) 		0.0511
(0.159) 		0.791
(0.876) 		0.0236
(0.0969) 		0.0201
(0.087) 		0.481
(0.678) 		0.036
(0.124) 		0.000457
(0.00493) 		0.271
(0.486) 		0.0152
(0.0705) 		0.563
(0.745)
del 10q23 31 158 (26%) 450 0.442
(0.65) 		0.00383
(0.0258) 		0.0748
(0.209) 		0.0343
(0.12) 		0.538
(0.728) 		0.0476
(0.152) 		0.143
(0.318) 		0.926
(0.965) 		0.0212
(0.0898) 		0.0116
(0.0598) 		0.698
(0.834) 		0.00933
(0.053) 		0.912
(0.956)
del 15q15 2 247 (41%) 361 0.742
(0.854) 		0.192
(0.389) 		0.0318
(0.118) 		0.0478
(0.152) 		0.857
(0.921) 		0.0036
(0.025) 		0.00397
(0.0265) 		0.322
(0.537) 		0.0189
(0.0836) 		0.0353
(0.123) 		0.524
(0.714) 		0.00193
(0.0154) 		0.176
(0.366)
amp 2q33 1 138 (23%) 470 0.0968
(0.239) 		0.993
(1.00) 		0.0116
(0.0598) 		0.025
(0.0999) 		0.87
(0.929) 		0.0006
(0.00593) 		0.315
(0.53) 		0.847
(0.916) 		0.00139
(0.0119) 		0.124
(0.286) 		0.382
(0.593) 		0.00156
(0.0131) 		0.242
(0.457)
amp 5p12 116 (19%) 492 0.196
(0.395) 		0.153
(0.334) 		0.0471
(0.151) 		0.288
(0.505) 		0.515
(0.707) 		0.0489
(0.154) 		0.0506
(0.158) 		0.607
(0.782) 		0.0149
(0.0698) 		0.383
(0.595) 		0.0527
(0.163) 		0.00998
(0.0554) 		0.668
(0.817)
del 1p33 173 (28%) 435 0.0332
(0.12) 		0.61
(0.782) 		0.309
(0.526) 		0.0314
(0.118) 		0.258
(0.471) 		0.021
(0.0898) 		0.0132
(0.0641) 		0.589
(0.767) 		0.0299
(0.113) 		0.719
(0.841) 		0.289
(0.506) 		0.00549
(0.0347) 		0.3
(0.517)
del 1p13 2 172 (28%) 436 0.054
(0.166) 		0.764
(0.859) 		0.22
(0.426) 		0.00613
(0.0375) 		0.138
(0.309) 		0.00722
(0.0431) 		0.00906
(0.0521) 		0.528
(0.719) 		0.071
(0.203) 		0.28
(0.496) 		0.357
(0.571) 		0.000497
(0.0053) 		0.462
(0.664)
del 4q22 1 218 (36%) 390 0.274
(0.488) 		0.176
(0.366) 		0.0166
(0.0762) 		0.02
(0.087) 		0.13
(0.293) 		0.00015
(0.00216) 		0.109
(0.264) 		0.108
(0.263) 		0.00364
(0.025) 		0.00156
(0.0131) 		0.788
(0.874) 		8.47e-05
(0.00136) 		0.705
(0.838)
del 5q21 2 184 (30%) 424 0.172
(0.362) 		0.161
(0.343) 		0.273
(0.488) 		0.0102
(0.0558) 		0.811
(0.891) 		0.00078
(0.00719) 		0.0102
(0.0558) 		0.93
(0.965) 		0.0534
(0.165) 		0.00042
(0.00475) 		0.621
(0.793) 		0.00097
(0.00877) 		0.596
(0.774)
del 6q26 91 (15%) 517 0.0173
(0.0785) 		0.713
(0.84) 		0.301
(0.518) 		0.191
(0.388) 		0.153
(0.333) 		0.00134
(0.0116) 		0.0663
(0.193) 		0.211
(0.416) 		0.0371
(0.127) 		0.63
(0.797) 		0.174
(0.364) 		0.00229
(0.0177) 		0.0171
(0.0782)
del 10p15 3 112 (18%) 496 0.54
(0.728) 		0.0334
(0.12) 		0.343
(0.559) 		0.0426
(0.14) 		0.655
(0.811) 		0.0229
(0.0955) 		0.0243
(0.0991) 		0.754
(0.857) 		0.4
(0.612) 		0.0131
(0.0639) 		0.879
(0.935) 		0.00405
(0.0267) 		0.598
(0.775)
del 10q21 1 135 (22%) 473 0.78
(0.871) 		0.034
(0.12) 		0.378
(0.591) 		0.0955
(0.237) 		0.923
(0.963) 		0.0802
(0.219) 		0.16
(0.343) 		0.845
(0.915) 		0.0386
(0.13) 		0.0292
(0.112) 		0.257
(0.471) 		0.0248
(0.0999) 		0.705
(0.838)
del 15q11 2 249 (41%) 359 0.642
(0.807) 		0.368
(0.583) 		0.136
(0.306) 		0.0637
(0.188) 		0.807
(0.888) 		0.0124
(0.0618) 		0.0235
(0.0969) 		0.41
(0.62) 		0.0771
(0.214) 		0.0362
(0.125) 		0.826
(0.9) 		0.00313
(0.0227) 		0.283
(0.499)
del 15q21 1 244 (40%) 364 0.555
(0.737) 		0.459
(0.662) 		0.0248
(0.0999) 		0.111
(0.266) 		0.837
(0.909) 		0.0153
(0.0706) 		0.00794
(0.0462) 		0.214
(0.418) 		0.0185
(0.0826) 		0.0342
(0.12) 		0.438
(0.647) 		0.00699
(0.042) 		0.103
(0.251)
del 17p12 364 (60%) 244 0.72
(0.841) 		0.166
(0.352) 		0.00203
(0.0161) 		0.00021
(0.00269) 		0.42
(0.628) 		5e-05
(0.000991) 		0.00169
(0.0138) 		0.508
(0.702) 		1e-05
(0.000256) 		0.327
(0.543) 		0.153
(0.333) 		7.41e-06
(0.000256) 		0.781
(0.871)
del 17q24 3 95 (16%) 513 0.0898
(0.231) 		0.255
(0.47) 		1
(1.00) 		0.0105
(0.0566) 		0.0958
(0.237) 		0.00165
(0.0137) 		0.0124
(0.0618) 		0.219
(0.425) 		0.99
(1.00) 		0.637
(0.803) 		0.38
(0.591) 		9.04e-05
(0.00143) 		0.161
(0.343)
del 19p13 3 96 (16%) 512 0.2
(0.399) 		0.256
(0.471) 		0.0767
(0.213) 		0.00779
(0.0456) 		0.373
(0.589) 		4e-05
(0.000825) 		0.00594
(0.037) 		0.267
(0.481) 		0.0871
(0.228) 		0.639
(0.804) 		0.156
(0.336) 		4.91e-06
(0.000256) 		0.914
(0.957)
del 22q13 32 225 (37%) 383 0.0354
(0.123) 		0.915
(0.957) 		0.253
(0.469) 		0.0129
(0.0633) 		0.343
(0.559) 		0.0002
(0.00267) 		0.00699
(0.042) 		0.449
(0.656) 		0.00741
(0.044) 		0.732
(0.848) 		0.41
(0.62) 		0.00021
(0.00269) 		0.493
(0.692)
amp 1q31 1 144 (24%) 464 0.537
(0.728) 		0.309
(0.526) 		0.0653
(0.192) 		0.38
(0.591) 		0.374
(0.589) 		0.0816
(0.222) 		0.0357
(0.123) 		0.215
(0.418) 		0.14
(0.312) 		0.0382
(0.13) 		0.711
(0.84) 		0.0124
(0.0618) 		0.928
(0.965)
amp 8q24 21 363 (60%) 245 0.47
(0.67) 		0.154
(0.334) 		0.0748
(0.209) 		0.07
(0.201) 		0.261
(0.476) 		0.146
(0.322) 		0.0116
(0.0598) 		0.214
(0.418) 		0.015
(0.0701) 		0.092
(0.232) 		0.182
(0.376) 		0.161
(0.343) 		0.572
(0.752)
amp 16p11 2 170 (28%) 438 0.867
(0.928) 		0.369
(0.583) 		0.759
(0.857) 		0.00064
(0.00613) 		0.744
(0.854) 		4e-05
(0.000825) 		0.0339
(0.12) 		0.857
(0.921) 		0.00183
(0.0147) 		0.275
(0.488) 		0.274
(0.488) 		5.01e-05
(0.000991) 		0.555
(0.737)
amp 20p11 21 359 (59%) 249 0.721
(0.841) 		0.693
(0.833) 		0.00883
(0.0511) 		0.0126
(0.0622) 		0.754
(0.857) 		0.345
(0.56) 		0.00117
(0.0105) 		0.0827
(0.222) 		1e-05
(0.000256) 		0.321
(0.537) 		0.397
(0.61) 		0.66
(0.812) 		0.798
(0.881)
del 10q25 2 154 (25%) 454 0.46
(0.663) 		0.0427
(0.14) 		0.207
(0.411) 		0.165
(0.349) 		0.282
(0.498) 		0.0243
(0.0991) 		0.18
(0.373) 		0.926
(0.965) 		0.0299
(0.113) 		0.0102
(0.0558) 		0.68
(0.823) 		0.0135
(0.0646) 		0.976
(0.999)
del 14q31 1 213 (35%) 395 0.746
(0.854) 		0.111
(0.266) 		0.0339
(0.12) 		0.541
(0.728) 		0.245
(0.461) 		0.025
(0.0999) 		0.0193
(0.0849) 		0.308
(0.526) 		1e-05
(0.000256) 		0.506
(0.701) 		0.736
(0.851) 		0.0401
(0.134) 		1
(1.00)
del 3q26 31 62 (10%) 546 0.376
(0.589) 		0.801
(0.883) 		0.879
(0.935) 		0.0327
(0.12) 		0.0977
(0.241) 		0.103
(0.25) 		0.0326
(0.12) 		0.423
(0.63) 		0.00946
(0.0534) 		1
(1.00) 		0.82
(0.896) 		0.16
(0.343) 		0.749
(0.855)
del 8q11 1 47 (8%) 561 0.566
(0.745) 		0.315
(0.53) 		0.226
(0.433) 		0.15
(0.33) 		0.676
(0.821) 		0.0628
(0.187) 		0.085
(0.226) 		0.227
(0.434) 		0.539
(0.728) 		0.518
(0.709) 		0.337
(0.552) 		0.0272
(0.106) 		0.0828
(0.222)
del 12p13 1 91 (15%) 517 0.0454
(0.147) 		0.29
(0.506) 		0.192
(0.389) 		0.25
(0.467) 		0.725
(0.845) 		0.0264
(0.104) 		0.0284
(0.109) 		0.82
(0.896) 		0.0159
(0.0735) 		0.63
(0.797) 		0.902
(0.949) 		0.119
(0.278) 		1
(1.00)
del 12q21 33 88 (14%) 520 0.114
(0.27) 		0.877
(0.935) 		0.36
(0.573) 		0.0711
(0.203) 		0.61
(0.782) 		0.0785
(0.217) 		0.399
(0.612) 		0.644
(0.807) 		0.0282
(0.109) 		0.625
(0.795) 		0.554
(0.737) 		0.0192
(0.0849) 		0.851
(0.92)
del 14q11 2 207 (34%) 401 0.701
(0.836) 		0.224
(0.432) 		0.0116
(0.0598) 		0.762
(0.857) 		0.341
(0.557) 		0.032
(0.119) 		0.0825
(0.222) 		1
(1.00) 		1e-05
(0.000256) 		0.498
(0.696) 		0.874
(0.933) 		0.146
(0.322) 		0.982
(1.00)
del 21q11 2 210 (35%) 398 0.357
(0.571) 		0.643
(0.807) 		0.00362
(0.025) 		0.441
(0.65) 		0.919
(0.961) 		0.0681
(0.197) 		0.387
(0.598) 		0.67
(0.818) 		7e-05
(0.00119) 		0.287
(0.505) 		0.611
(0.782) 		0.0174
(0.0785) 		0.479
(0.677)
amp 11p15 5 136 (22%) 472 0.65
(0.809) 		0.0303
(0.114) 		0.078
(0.216) 		0.825
(0.9) 		0.257
(0.471) 		0.314
(0.53) 		0.264
(0.479) 		0.698
(0.834) 		0.00123
(0.0109) 		0.119
(0.278) 		0.853
(0.92) 		0.251
(0.467) 		0.565
(0.745)
amp 17q12 158 (26%) 450 0.04
(0.134) 		0.147
(0.322) 		0.465
(0.667) 		0.251
(0.467) 		0.254
(0.469) 		0.129
(0.293) 		0.00413
(0.0271) 		0.138
(0.31) 		0.409
(0.62) 		0.458
(0.662) 		0.0485
(0.154) 		0.189
(0.387) 		0.191
(0.388)
amp 17q24 1 142 (23%) 466 0.00349
(0.0245) 		0.208
(0.412) 		1
(1.00) 		0.712
(0.84) 		0.854
(0.92) 		0.94
(0.97) 		0.0905
(0.231) 		0.565
(0.745) 		0.0865
(0.228) 		0.693
(0.833) 		0.104
(0.253) 		0.757
(0.857) 		0.761
(0.857)
del 3p14 2 116 (19%) 492 0.344
(0.559) 		0.246
(0.462) 		0.814
(0.893) 		0.226
(0.433) 		0.101
(0.248) 		0.235
(0.447) 		0.023
(0.0955) 		0.471
(0.67) 		0.722
(0.842) 		0.684
(0.826) 		0.293
(0.509) 		0.0893
(0.231) 		0.601
(0.777)
del 6p25 3 78 (13%) 530 0.126
(0.29) 		0.0617
(0.185) 		0.782
(0.871) 		0.429
(0.638) 		0.449
(0.656) 		0.494
(0.692) 		0.859
(0.922) 		0.0687
(0.198) 		0.475
(0.671) 		0.324
(0.54) 		0.452
(0.659) 		0.455
(0.66) 		0.00292
(0.0213)
del 9p24 2 82 (13%) 526 0.266
(0.481) 		0.11
(0.266) 		0.281
(0.497) 		0.782
(0.871) 		0.468
(0.668) 		0.141
(0.314) 		0.0607
(0.184) 		0.0437
(0.143) 		0.112
(0.268) 		0.348
(0.562) 		0.135
(0.305) 		0.0337
(0.12) 		0.662
(0.812)
del 11q22 3 110 (18%) 498 0.305
(0.523) 		0.419
(0.628) 		0.0711
(0.203) 		0.674
(0.819) 		0.715
(0.84) 		0.172
(0.362) 		0.358
(0.571) 		0.673
(0.819) 		0.0435
(0.142) 		0.212
(0.417) 		0.543
(0.73) 		0.066
(0.193) 		0.333
(0.549)
del 16p13 3 67 (11%) 541 0.00336
(0.0241) 		0.784
(0.872) 		0.187
(0.385) 		0.0118
(0.0602) 		0.0558
(0.171) 		0.199
(0.399) 		0.185
(0.38) 		0.795
(0.879) 		0.235
(0.447) 		0.607
(0.782) 		0.445
(0.652) 		0.129
(0.293) 		0.346
(0.561)
del 20p12 1 132 (22%) 476 0.889
(0.941) 		0.35
(0.563) 		0.00528
(0.0338) 		0.129
(0.293) 		0.742
(0.854) 		0.196
(0.395) 		0.888
(0.941) 		0.622
(0.793) 		0.00401
(0.0266) 		0.217
(0.421) 		0.564
(0.745) 		0.0613
(0.184) 		0.229
(0.436)
amp 5q22 3 64 (11%) 544 0.199
(0.399) 		0.695
(0.834) 		0.455
(0.66) 		0.652
(0.809) 		0.95
(0.978) 		0.414
(0.623) 		0.0326
(0.12) 		0.895
(0.945) 		0.212
(0.417) 		1
(1.00) 		0.0576
(0.176) 		0.226
(0.433) 		0.552
(0.737)
amp 8p11 21 253 (42%) 355 0.893
(0.943) 		0.445
(0.652) 		0.71
(0.84) 		0.113
(0.268) 		0.509
(0.703) 		0.349
(0.563) 		0.0739
(0.209) 		0.189
(0.387) 		0.251
(0.467) 		0.742
(0.854) 		0.0255
(0.101) 		0.47
(0.67) 		0.549
(0.735)
amp 10q22 3 39 (6%) 569 0.897
(0.946) 		0.401
(0.613) 		0.852
(0.92) 		0.662
(0.812) 		0.316
(0.53) 		0.0748
(0.209) 		0.806
(0.887) 		0.741
(0.854) 		0.93
(0.965) 		0.452
(0.658) 		0.931
(0.965) 		0.09
(0.231) 		1
(1.00)
amp 12p13 32 150 (25%) 458 0.113
(0.269) 		0.123
(0.285) 		0.75
(0.855) 		0.0802
(0.219) 		0.376
(0.589) 		0.0829
(0.222) 		1
(1.00) 		0.778
(0.871) 		0.49
(0.687) 		0.696
(0.834) 		0.762
(0.857) 		0.316
(0.53) 		0.702
(0.836)
amp 15q26 1 42 (7%) 566 0.374
(0.589) 		0.787
(0.874) 		0.588
(0.767) 		0.145
(0.322) 		0.332
(0.549) 		0.00287
(0.0211) 		0.65
(0.809) 		0.201
(0.4) 		0.523
(0.714) 		0.123
(0.285) 		0.473
(0.671) 		0.00383
(0.0258) 		0.715
(0.84)
amp 19q12 138 (23%) 470 0.538
(0.728) 		0.508
(0.702) 		0.127
(0.291) 		0.522
(0.714) 		0.866
(0.928) 		0.128
(0.292) 		0.0148
(0.0698) 		0.286
(0.504) 		0.0196
(0.0859) 		1
(1.00) 		0.414
(0.623) 		0.241
(0.456) 		0.663
(0.812)
del 2p12 21 (3%) 587 0.909
(0.955) 		0.127
(0.291) 		0.000623
(0.0061) 		0.402
(0.613) 		1
(1.00) 		0.466
(0.667) 		0.755
(0.857) 		0.661
(0.812) 		0.00589
(0.037) 		0.273
(0.488) 		0.887
(0.941) 		0.399
(0.612) 		0.673
(0.819)
amp 8p11 23 209 (34%) 399 0.473
(0.671) 		0.749
(0.855) 		0.629
(0.797) 		0.265
(0.481) 		0.587
(0.767) 		0.515
(0.707) 		0.618
(0.789) 		0.608
(0.782) 		0.311
(0.53) 		0.502
(0.699) 		0.0797
(0.219) 		0.72
(0.841) 		0.745
(0.854)
amp 19p13 2 111 (18%) 497 0.75
(0.855) 		0.757
(0.857) 		0.155
(0.335) 		0.792
(0.876) 		0.472
(0.671) 		0.111
(0.266) 		0.349
(0.563) 		0.294
(0.509) 		0.0506
(0.158) 		1
(1.00) 		0.121
(0.282) 		0.414
(0.623) 		0.453
(0.659)
del 2q22 1 35 (6%) 573 0.732
(0.848) 		0.831
(0.903) 		0.556
(0.738) 		0.322
(0.537) 		0.632
(0.797) 		0.573
(0.752) 		0.333
(0.549) 		0.728
(0.846) 		0.906
(0.952) 		1
(1.00) 		0.932
(0.965) 		0.241
(0.456) 		0.0115
(0.0598)
del 16q23 1 81 (13%) 527 0.0263
(0.104) 		0.661
(0.812) 		0.788
(0.874) 		0.334
(0.55) 		0.2
(0.4) 		0.554
(0.737) 		0.387
(0.598) 		0.403
(0.614) 		0.76
(0.857) 		1
(1.00) 		0.89
(0.941) 		0.971
(0.995) 		0.362
(0.575)
del 7q31 1 16 (3%) 592 0.961
(0.987) 		0.558
(0.739) 		1
(1.00) 		0.719
(0.841) 		0.514
(0.707) 		0.94
(0.97) 		0.489
(0.687) 		0.613
(0.784) 		0.487
(0.685) 		1
(1.00) 		0.631
(0.797) 		0.699
(0.834) 		0.463
(0.665)
'amp_1q31.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0653 (Fisher's exact test), Q value = 0.19

Table S1.  Gene #1: 'amp_1q31.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 1(1Q31.1) MUTATED 95 47
AMP PEAK 1(1Q31.1) WILD-TYPE 347 115

Figure S1.  Get High-res Image Gene #1: 'amp_1q31.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_1q31.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0816 (Fisher's exact test), Q value = 0.22

Table S2.  Gene #1: 'amp_1q31.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 1(1Q31.1) MUTATED 69 38 34
AMP PEAK 1(1Q31.1) WILD-TYPE 273 111 80

Figure S2.  Get High-res Image Gene #1: 'amp_1q31.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_1q31.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0357 (Fisher's exact test), Q value = 0.12

Table S3.  Gene #1: 'amp_1q31.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 1(1Q31.1) MUTATED 96 28
AMP PEAK 1(1Q31.1) WILD-TYPE 352 58

Figure S3.  Get High-res Image Gene #1: 'amp_1q31.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_1q31.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0382 (Fisher's exact test), Q value = 0.13

Table S4.  Gene #1: 'amp_1q31.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 1(1Q31.1) MUTATED 5 139
AMP PEAK 1(1Q31.1) WILD-TYPE 4 460

Figure S4.  Get High-res Image Gene #1: 'amp_1q31.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_1q31.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0124 (Wilcoxon-test), Q value = 0.062

Table S5.  Gene #1: 'amp_1q31.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 1(1Q31.1) MUTATED 136 3.1 (5.6)
AMP PEAK 1(1Q31.1) WILD-TYPE 437 1.9 (4.4)

Figure S5.  Get High-res Image Gene #1: 'amp_1q31.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_2q33.1' versus 'Time to Death'

P value = 0.0968 (logrank test), Q value = 0.24

Table S6.  Gene #2: 'amp_2q33.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
AMP PEAK 2(2Q33.1) MUTATED 131 30 0.0 - 129.3 (18.2)
AMP PEAK 2(2Q33.1) WILD-TYPE 452 85 0.0 - 140.4 (19.2)

Figure S6.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #1: 'Time to Death'

'amp_2q33.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0116 (Fisher's exact test), Q value = 0.06

Table S7.  Gene #2: 'amp_2q33.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 2(2Q33.1) MUTATED 89 49
AMP PEAK 2(2Q33.1) WILD-TYPE 353 113

Figure S7.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_2q33.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.025 (Fisher's exact test), Q value = 0.1

Table S8.  Gene #2: 'amp_2q33.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 2(2Q33.1) MUTATED 21 0 8 28 0 2 6 4 21 22 14 6 1
AMP PEAK 2(2Q33.1) WILD-TYPE 83 1 28 143 10 1 20 17 58 32 47 21 1

Figure S8.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_2q33.1' versus 'PATHOLOGY_N_STAGE'

P value = 6e-04 (Fisher's exact test), Q value = 0.0059

Table S9.  Gene #2: 'amp_2q33.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 2(2Q33.1) MUTATED 61 34 41
AMP PEAK 2(2Q33.1) WILD-TYPE 281 115 73

Figure S9.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_2q33.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.00139 (Fisher's exact test), Q value = 0.012

Table S10.  Gene #2: 'amp_2q33.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 2(2Q33.1) MUTATED 79 10 49 0
AMP PEAK 2(2Q33.1) WILD-TYPE 302 50 97 13

Figure S10.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_2q33.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00156 (Wilcoxon-test), Q value = 0.013

Table S11.  Gene #2: 'amp_2q33.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 2(2Q33.1) MUTATED 130 3.2 (5.3)
AMP PEAK 2(2Q33.1) WILD-TYPE 443 2.0 (4.5)

Figure S11.  Get High-res Image Gene #2: 'amp_2q33.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_5p12' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0471 (Fisher's exact test), Q value = 0.15

Table S12.  Gene #3: 'amp_5p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 3(5P12) MUTATED 76 40
AMP PEAK 3(5P12) WILD-TYPE 366 122

Figure S12.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_5p12' versus 'PATHOLOGY_N_STAGE'

P value = 0.0489 (Fisher's exact test), Q value = 0.15

Table S13.  Gene #3: 'amp_5p12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 3(5P12) MUTATED 54 32 29
AMP PEAK 3(5P12) WILD-TYPE 288 117 85

Figure S13.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_5p12' versus 'PATHOLOGY_M_STAGE'

P value = 0.0506 (Fisher's exact test), Q value = 0.16

Table S14.  Gene #3: 'amp_5p12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 3(5P12) MUTATED 78 23
AMP PEAK 3(5P12) WILD-TYPE 370 63

Figure S14.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_5p12' versus 'HISTOLOGICAL_TYPE'

P value = 0.0149 (Fisher's exact test), Q value = 0.07

Table S15.  Gene #3: 'amp_5p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 3(5P12) MUTATED 67 9 40 0
AMP PEAK 3(5P12) WILD-TYPE 314 51 106 13

Figure S15.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_5p12' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0527 (Fisher's exact test), Q value = 0.16

Table S16.  Gene #3: 'amp_5p12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 3(5P12) MUTATED 84 1 13 3
AMP PEAK 3(5P12) WILD-TYPE 355 4 23 26

Figure S16.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_5p12' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00998 (Wilcoxon-test), Q value = 0.055

Table S17.  Gene #3: 'amp_5p12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 3(5P12) MUTATED 112 3.0 (4.7)
AMP PEAK 3(5P12) WILD-TYPE 461 2.0 (4.7)

Figure S17.  Get High-res Image Gene #3: 'amp_5p12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_5q22.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.0326 (Fisher's exact test), Q value = 0.12

Table S18.  Gene #4: 'amp_5q22.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 4(5Q22.3) MUTATED 41 15
AMP PEAK 4(5Q22.3) WILD-TYPE 407 71

Figure S18.  Get High-res Image Gene #4: 'amp_5q22.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_5q22.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0576 (Fisher's exact test), Q value = 0.18

Table S19.  Gene #4: 'amp_5q22.3' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 4(5Q22.3) MUTATED 44 0 7 0
AMP PEAK 4(5Q22.3) WILD-TYPE 395 5 29 29

Figure S19.  Get High-res Image Gene #4: 'amp_5q22.3' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_6p21.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0336 (Fisher's exact test), Q value = 0.12

Table S20.  Gene #5: 'amp_6p21.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 5(6P21.1) MUTATED 100 51
AMP PEAK 5(6P21.1) WILD-TYPE 342 111

Figure S20.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_6p21.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.012 (Fisher's exact test), Q value = 0.061

Table S21.  Gene #5: 'amp_6p21.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 5(6P21.1) MUTATED 21 0 4 33 1 1 7 7 25 20 19 12 1
AMP PEAK 5(6P21.1) WILD-TYPE 83 1 32 138 9 2 19 14 54 34 42 15 1

Figure S21.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_6p21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00014 (Fisher's exact test), Q value = 0.002

Table S22.  Gene #5: 'amp_6p21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 5(6P21.1) MUTATED 67 41 45
AMP PEAK 5(6P21.1) WILD-TYPE 275 108 69

Figure S22.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_6p21.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0137 (Fisher's exact test), Q value = 0.065

Table S23.  Gene #5: 'amp_6p21.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 5(6P21.1) MUTATED 102 31
AMP PEAK 5(6P21.1) WILD-TYPE 346 55

Figure S23.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_6p21.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.00758 (Fisher's exact test), Q value = 0.045

Table S24.  Gene #5: 'amp_6p21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 5(6P21.1) MUTATED 91 9 50 1
AMP PEAK 5(6P21.1) WILD-TYPE 290 51 96 12

Figure S24.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_6p21.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00134 (Fisher's exact test), Q value = 0.012

Table S25.  Gene #5: 'amp_6p21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 5(6P21.1) MUTATED 7 147
AMP PEAK 5(6P21.1) WILD-TYPE 2 452

Figure S25.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_6p21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000207 (Wilcoxon-test), Q value = 0.0027

Table S26.  Gene #5: 'amp_6p21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 5(6P21.1) MUTATED 148 3.4 (6.0)
AMP PEAK 5(6P21.1) WILD-TYPE 425 1.8 (4.1)

Figure S26.  Get High-res Image Gene #5: 'amp_6p21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_7p21.3' versus 'YEARS_TO_BIRTH'

P value = 0.066 (Wilcoxon-test), Q value = 0.19

Table S27.  Gene #6: 'amp_7p21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
AMP PEAK 6(7P21.3) MUTATED 358 65.6 (12.2)
AMP PEAK 6(7P21.3) WILD-TYPE 248 67.2 (13.4)

Figure S27.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_7p21.3' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0249 (Fisher's exact test), Q value = 0.1

Table S28.  Gene #6: 'amp_7p21.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 6(7P21.3) MUTATED 249 108
AMP PEAK 6(7P21.3) WILD-TYPE 193 54

Figure S28.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_7p21.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 6e-05 (Fisher's exact test), Q value = 0.0011

Table S29.  Gene #6: 'amp_7p21.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 6(7P21.3) MUTATED 57 1 19 77 3 2 15 15 59 38 42 21 1
AMP PEAK 6(7P21.3) WILD-TYPE 47 0 17 94 7 1 11 6 20 16 19 6 1

Figure S29.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_7p21.3' versus 'PATHOLOGY_N_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S30.  Gene #6: 'amp_7p21.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 6(7P21.3) MUTATED 171 108 77
AMP PEAK 6(7P21.3) WILD-TYPE 171 41 37

Figure S30.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_7p21.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.0119 (Fisher's exact test), Q value = 0.06

Table S31.  Gene #6: 'amp_7p21.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 6(7P21.3) MUTATED 250 61
AMP PEAK 6(7P21.3) WILD-TYPE 198 25

Figure S31.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_7p21.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.00073 (Fisher's exact test), Q value = 0.0068

Table S32.  Gene #6: 'amp_7p21.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 6(7P21.3) MUTATED 224 25 102 5
AMP PEAK 6(7P21.3) WILD-TYPE 157 35 44 8

Figure S32.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_7p21.3' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0897 (Fisher's exact test), Q value = 0.23

Table S33.  Gene #6: 'amp_7p21.3' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 6(7P21.3) MUTATED 8 351
AMP PEAK 6(7P21.3) WILD-TYPE 1 248

Figure S33.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_7p21.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 5.17e-05 (Wilcoxon-test), Q value = 0.001

Table S34.  Gene #6: 'amp_7p21.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 6(7P21.3) MUTATED 340 2.6 (5.1)
AMP PEAK 6(7P21.3) WILD-TYPE 233 1.7 (4.0)

Figure S34.  Get High-res Image Gene #6: 'amp_7p21.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_8p11.23' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0797 (Fisher's exact test), Q value = 0.22

Table S35.  Gene #7: 'amp_8p11.23' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 7(8P11.23) MUTATED 143 1 16 15
AMP PEAK 7(8P11.23) WILD-TYPE 296 4 20 14

Figure S35.  Get High-res Image Gene #7: 'amp_8p11.23' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_8p11.21' versus 'PATHOLOGY_M_STAGE'

P value = 0.0739 (Fisher's exact test), Q value = 0.21

Table S36.  Gene #8: 'amp_8p11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 8(8P11.21) MUTATED 177 43
AMP PEAK 8(8P11.21) WILD-TYPE 271 43

Figure S36.  Get High-res Image Gene #8: 'amp_8p11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_8p11.21' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0255 (Fisher's exact test), Q value = 0.1

Table S37.  Gene #8: 'amp_8p11.21' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 8(8P11.21) MUTATED 172 2 22 16
AMP PEAK 8(8P11.21) WILD-TYPE 267 3 14 13

Figure S37.  Get High-res Image Gene #8: 'amp_8p11.21' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_8q12.1' versus 'YEARS_TO_BIRTH'

P value = 0.0951 (Wilcoxon-test), Q value = 0.24

Table S38.  Gene #9: 'amp_8q12.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
AMP PEAK 9(8Q12.1) MUTATED 325 65.6 (12.3)
AMP PEAK 9(8Q12.1) WILD-TYPE 281 67.0 (13.2)

Figure S38.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_8q12.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0531 (Fisher's exact test), Q value = 0.16

Table S39.  Gene #9: 'amp_8q12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 9(8Q12.1) MUTATED 48 0 22 86 4 3 11 12 43 33 43 14 0
AMP PEAK 9(8Q12.1) WILD-TYPE 56 1 14 85 6 0 15 9 36 21 18 13 2

Figure S39.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_8q12.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.101 (Fisher's exact test), Q value = 0.25

Table S40.  Gene #9: 'amp_8q12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 9(8Q12.1) MUTATED 174 78 71
AMP PEAK 9(8Q12.1) WILD-TYPE 168 71 43

Figure S40.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_8q12.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.00919 (Fisher's exact test), Q value = 0.053

Table S41.  Gene #9: 'amp_8q12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 9(8Q12.1) MUTATED 226 57
AMP PEAK 9(8Q12.1) WILD-TYPE 222 29

Figure S41.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_8q12.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0226 (Fisher's exact test), Q value = 0.094

Table S42.  Gene #9: 'amp_8q12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 9(8Q12.1) MUTATED 209 24 87 4
AMP PEAK 9(8Q12.1) WILD-TYPE 172 36 59 9

Figure S42.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_8q12.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0421 (Fisher's exact test), Q value = 0.14

Table S43.  Gene #9: 'amp_8q12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 9(8Q12.1) MUTATED 8 318
AMP PEAK 9(8Q12.1) WILD-TYPE 1 281

Figure S43.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_8q12.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0863 (Fisher's exact test), Q value = 0.23

Table S44.  Gene #9: 'amp_8q12.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 9(8Q12.1) MUTATED 225 3 26 17
AMP PEAK 9(8Q12.1) WILD-TYPE 214 2 10 12

Figure S44.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_8q12.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0884 (Wilcoxon-test), Q value = 0.23

Table S45.  Gene #9: 'amp_8q12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 9(8Q12.1) MUTATED 306 2.6 (5.3)
AMP PEAK 9(8Q12.1) WILD-TYPE 267 1.8 (3.9)

Figure S45.  Get High-res Image Gene #9: 'amp_8q12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_8q24.21' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0748 (Fisher's exact test), Q value = 0.21

Table S46.  Gene #10: 'amp_8q24.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 10(8Q24.21) MUTATED 255 107
AMP PEAK 10(8Q24.21) WILD-TYPE 187 55

Figure S46.  Get High-res Image Gene #10: 'amp_8q24.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_8q24.21' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.07 (Fisher's exact test), Q value = 0.2

Table S47.  Gene #10: 'amp_8q24.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 10(8Q24.21) MUTATED 56 0 24 97 4 3 13 15 47 34 46 16 0
AMP PEAK 10(8Q24.21) WILD-TYPE 48 1 12 74 6 0 13 6 32 20 15 11 2

Figure S47.  Get High-res Image Gene #10: 'amp_8q24.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_8q24.21' versus 'PATHOLOGY_M_STAGE'

P value = 0.0116 (Fisher's exact test), Q value = 0.06

Table S48.  Gene #10: 'amp_8q24.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 10(8Q24.21) MUTATED 257 62
AMP PEAK 10(8Q24.21) WILD-TYPE 191 24

Figure S48.  Get High-res Image Gene #10: 'amp_8q24.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_8q24.21' versus 'HISTOLOGICAL_TYPE'

P value = 0.015 (Fisher's exact test), Q value = 0.07

Table S49.  Gene #10: 'amp_8q24.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 10(8Q24.21) MUTATED 225 29 100 5
AMP PEAK 10(8Q24.21) WILD-TYPE 156 31 46 8

Figure S49.  Get High-res Image Gene #10: 'amp_8q24.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_8q24.21' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.092 (Fisher's exact test), Q value = 0.23

Table S50.  Gene #10: 'amp_8q24.21' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 10(8Q24.21) MUTATED 8 355
AMP PEAK 10(8Q24.21) WILD-TYPE 1 244

Figure S50.  Get High-res Image Gene #10: 'amp_8q24.21' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_10q22.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0748 (Fisher's exact test), Q value = 0.21

Table S51.  Gene #11: 'amp_10q22.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 11(10Q22.3) MUTATED 16 11 12
AMP PEAK 11(10Q22.3) WILD-TYPE 326 138 102

Figure S51.  Get High-res Image Gene #11: 'amp_10q22.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_10q22.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.09 (Wilcoxon-test), Q value = 0.23

Table S52.  Gene #11: 'amp_10q22.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 11(10Q22.3) MUTATED 37 4.4 (9.1)
AMP PEAK 11(10Q22.3) WILD-TYPE 536 2.1 (4.2)

Figure S52.  Get High-res Image Gene #11: 'amp_10q22.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_11p15.5' versus 'YEARS_TO_BIRTH'

P value = 0.0303 (Wilcoxon-test), Q value = 0.11

Table S53.  Gene #12: 'amp_11p15.5' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
AMP PEAK 12(11P15.5) MUTATED 136 64.3 (12.1)
AMP PEAK 12(11P15.5) WILD-TYPE 470 66.8 (12.9)

Figure S53.  Get High-res Image Gene #12: 'amp_11p15.5' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_11p15.5' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.078 (Fisher's exact test), Q value = 0.22

Table S54.  Gene #12: 'amp_11p15.5' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 12(11P15.5) MUTATED 90 44
AMP PEAK 12(11P15.5) WILD-TYPE 352 118

Figure S54.  Get High-res Image Gene #12: 'amp_11p15.5' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_11p15.5' versus 'HISTOLOGICAL_TYPE'

P value = 0.00123 (Fisher's exact test), Q value = 0.011

Table S55.  Gene #12: 'amp_11p15.5' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 12(11P15.5) MUTATED 85 4 43 1
AMP PEAK 12(11P15.5) WILD-TYPE 296 56 103 12

Figure S55.  Get High-res Image Gene #12: 'amp_11p15.5' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_12p13.32' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0802 (Fisher's exact test), Q value = 0.22

Table S56.  Gene #13: 'amp_12p13.32' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 13(12P13.32) MUTATED 23 1 13 50 2 1 5 7 9 14 15 8 0
AMP PEAK 13(12P13.32) WILD-TYPE 81 0 23 121 8 2 21 14 70 40 46 19 2

Figure S56.  Get High-res Image Gene #13: 'amp_12p13.32' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_12p13.32' versus 'PATHOLOGY_N_STAGE'

P value = 0.0829 (Fisher's exact test), Q value = 0.22

Table S57.  Gene #13: 'amp_12p13.32' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 13(12P13.32) MUTATED 94 27 29
AMP PEAK 13(12P13.32) WILD-TYPE 248 122 85

Figure S57.  Get High-res Image Gene #13: 'amp_12p13.32' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_13q12.13' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.000528 (Fisher's exact test), Q value = 0.0055

Table S58.  Gene #14: 'amp_13q12.13' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 14(13Q12.13) MUTATED 269 123
AMP PEAK 14(13Q12.13) WILD-TYPE 173 39

Figure S58.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_13q12.13' versus 'NEOPLASM_DISEASESTAGE'

P value = 2e-05 (Fisher's exact test), Q value = 5e-04

Table S59.  Gene #14: 'amp_13q12.13' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 14(13Q12.13) MUTATED 64 0 16 98 4 3 15 17 59 39 50 23 0
AMP PEAK 14(13Q12.13) WILD-TYPE 40 1 20 73 6 0 11 4 20 15 11 4 2

Figure S59.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_13q12.13' versus 'PATHOLOGY_N_STAGE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00083

Table S60.  Gene #14: 'amp_13q12.13' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 14(13Q12.13) MUTATED 195 113 86
AMP PEAK 14(13Q12.13) WILD-TYPE 147 36 28

Figure S60.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_13q12.13' versus 'PATHOLOGY_M_STAGE'

P value = 0.00127 (Fisher's exact test), Q value = 0.011

Table S61.  Gene #14: 'amp_13q12.13' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 14(13Q12.13) MUTATED 280 69
AMP PEAK 14(13Q12.13) WILD-TYPE 168 17

Figure S61.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_13q12.13' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S62.  Gene #14: 'amp_13q12.13' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 14(13Q12.13) MUTATED 251 18 117 5
AMP PEAK 14(13Q12.13) WILD-TYPE 130 42 29 8

Figure S62.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_13q12.13' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0459 (Fisher's exact test), Q value = 0.15

Table S63.  Gene #14: 'amp_13q12.13' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 14(13Q12.13) MUTATED 281 3 28 13
AMP PEAK 14(13Q12.13) WILD-TYPE 158 2 8 16

Figure S63.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_13q12.13' versus 'NUMBER_OF_LYMPH_NODES'

P value = 5.52e-05 (Wilcoxon-test), Q value = 0.001

Table S64.  Gene #14: 'amp_13q12.13' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 14(13Q12.13) MUTATED 377 2.5 (4.9)
AMP PEAK 14(13Q12.13) WILD-TYPE 196 1.6 (4.2)

Figure S64.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_13q12.13' versus 'RACE'

P value = 0.0188 (Fisher's exact test), Q value = 0.084

Table S65.  Gene #14: 'amp_13q12.13' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
AMP PEAK 14(13Q12.13) MUTATED 0 4 39 204
AMP PEAK 14(13Q12.13) WILD-TYPE 1 8 21 88

Figure S65.  Get High-res Image Gene #14: 'amp_13q12.13' versus Clinical Feature #13: 'RACE'

'amp_13q12.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.000543 (Fisher's exact test), Q value = 0.0055

Table S66.  Gene #15: 'amp_13q12.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 15(13Q12.2) MUTATED 265 122
AMP PEAK 15(13Q12.2) WILD-TYPE 177 40

Figure S66.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_13q12.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 7e-05 (Fisher's exact test), Q value = 0.0012

Table S67.  Gene #15: 'amp_13q12.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 15(13Q12.2) MUTATED 64 0 16 96 4 3 15 17 59 38 49 22 0
AMP PEAK 15(13Q12.2) WILD-TYPE 40 1 20 75 6 0 11 4 20 16 12 5 2

Figure S67.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_13q12.2' versus 'PATHOLOGY_N_STAGE'

P value = 3e-05 (Fisher's exact test), Q value = 0.00069

Table S68.  Gene #15: 'amp_13q12.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 15(13Q12.2) MUTATED 193 111 85
AMP PEAK 15(13Q12.2) WILD-TYPE 149 38 29

Figure S68.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_13q12.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.00452 (Fisher's exact test), Q value = 0.029

Table S69.  Gene #15: 'amp_13q12.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 15(13Q12.2) MUTATED 277 67
AMP PEAK 15(13Q12.2) WILD-TYPE 171 19

Figure S69.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_13q12.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S70.  Gene #15: 'amp_13q12.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 15(13Q12.2) MUTATED 247 18 116 5
AMP PEAK 15(13Q12.2) WILD-TYPE 134 42 30 8

Figure S70.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_13q12.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0833 (Fisher's exact test), Q value = 0.22

Table S71.  Gene #15: 'amp_13q12.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 15(13Q12.2) MUTATED 278 3 27 13
AMP PEAK 15(13Q12.2) WILD-TYPE 161 2 9 16

Figure S71.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_13q12.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 6.93e-05 (Wilcoxon-test), Q value = 0.0012

Table S72.  Gene #15: 'amp_13q12.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 15(13Q12.2) MUTATED 373 2.5 (4.9)
AMP PEAK 15(13Q12.2) WILD-TYPE 200 1.6 (4.2)

Figure S72.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_13q12.2' versus 'RACE'

P value = 0.0266 (Fisher's exact test), Q value = 0.1

Table S73.  Gene #15: 'amp_13q12.2' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
AMP PEAK 15(13Q12.2) MUTATED 0 4 39 201
AMP PEAK 15(13Q12.2) WILD-TYPE 1 8 21 91

Figure S73.  Get High-res Image Gene #15: 'amp_13q12.2' versus Clinical Feature #13: 'RACE'

'amp_13q22.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.021 (Fisher's exact test), Q value = 0.09

Table S74.  Gene #16: 'amp_13q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 16(13Q22.1) MUTATED 273 117
AMP PEAK 16(13Q22.1) WILD-TYPE 169 45

Figure S74.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_13q22.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00054 (Fisher's exact test), Q value = 0.0055

Table S75.  Gene #16: 'amp_13q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 16(13Q22.1) MUTATED 65 0 20 93 4 3 16 17 58 40 48 21 0
AMP PEAK 16(13Q22.1) WILD-TYPE 39 1 16 78 6 0 10 4 21 14 13 6 2

Figure S75.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_13q22.1' versus 'PATHOLOGY_N_STAGE'

P value = 6e-05 (Fisher's exact test), Q value = 0.0011

Table S76.  Gene #16: 'amp_13q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 16(13Q22.1) MUTATED 195 112 84
AMP PEAK 16(13Q22.1) WILD-TYPE 147 37 30

Figure S76.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_13q22.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.00965 (Fisher's exact test), Q value = 0.054

Table S77.  Gene #16: 'amp_13q22.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 16(13Q22.1) MUTATED 278 66
AMP PEAK 16(13Q22.1) WILD-TYPE 170 20

Figure S77.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_13q22.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S78.  Gene #16: 'amp_13q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 16(13Q22.1) MUTATED 253 20 112 4
AMP PEAK 16(13Q22.1) WILD-TYPE 128 40 34 9

Figure S78.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_13q22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000321 (Wilcoxon-test), Q value = 0.0039

Table S79.  Gene #16: 'amp_13q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 16(13Q22.1) MUTATED 377 2.4 (4.7)
AMP PEAK 16(13Q22.1) WILD-TYPE 196 1.8 (4.7)

Figure S79.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_13q22.1' versus 'RACE'

P value = 0.0952 (Fisher's exact test), Q value = 0.24

Table S80.  Gene #16: 'amp_13q22.1' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
AMP PEAK 16(13Q22.1) MUTATED 0 5 40 201
AMP PEAK 16(13Q22.1) WILD-TYPE 1 7 20 91

Figure S80.  Get High-res Image Gene #16: 'amp_13q22.1' versus Clinical Feature #13: 'RACE'

'amp_15q26.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00287 (Fisher's exact test), Q value = 0.021

Table S81.  Gene #17: 'amp_15q26.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 17(15Q26.1) MUTATED 17 8 17
AMP PEAK 17(15Q26.1) WILD-TYPE 325 141 97

Figure S81.  Get High-res Image Gene #17: 'amp_15q26.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_15q26.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00383 (Wilcoxon-test), Q value = 0.026

Table S82.  Gene #17: 'amp_15q26.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 17(15Q26.1) MUTATED 39 4.1 (6.3)
AMP PEAK 17(15Q26.1) WILD-TYPE 534 2.1 (4.6)

Figure S82.  Get High-res Image Gene #17: 'amp_15q26.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_16p11.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00064 (Fisher's exact test), Q value = 0.0061

Table S83.  Gene #18: 'amp_16p11.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 18(16P11.2) MUTATED 20 1 4 37 3 0 6 10 31 21 23 8 1
AMP PEAK 18(16P11.2) WILD-TYPE 84 0 32 134 7 3 20 11 48 33 38 19 1

Figure S83.  Get High-res Image Gene #18: 'amp_16p11.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_16p11.2' versus 'PATHOLOGY_N_STAGE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00083

Table S84.  Gene #18: 'amp_16p11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 18(16P11.2) MUTATED 71 55 43
AMP PEAK 18(16P11.2) WILD-TYPE 271 94 71

Figure S84.  Get High-res Image Gene #18: 'amp_16p11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_16p11.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0339 (Fisher's exact test), Q value = 0.12

Table S85.  Gene #18: 'amp_16p11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 18(16P11.2) MUTATED 114 32
AMP PEAK 18(16P11.2) WILD-TYPE 334 54

Figure S85.  Get High-res Image Gene #18: 'amp_16p11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_16p11.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.00183 (Fisher's exact test), Q value = 0.015

Table S86.  Gene #18: 'amp_16p11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 18(16P11.2) MUTATED 114 8 47 0
AMP PEAK 18(16P11.2) WILD-TYPE 267 52 99 13

Figure S86.  Get High-res Image Gene #18: 'amp_16p11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_16p11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 5.01e-05 (Wilcoxon-test), Q value = 0.00099

Table S87.  Gene #18: 'amp_16p11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 18(16P11.2) MUTATED 162 3.1 (5.9)
AMP PEAK 18(16P11.2) WILD-TYPE 411 1.9 (4.1)

Figure S87.  Get High-res Image Gene #18: 'amp_16p11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_17q12' versus 'Time to Death'

P value = 0.04 (logrank test), Q value = 0.13

Table S88.  Gene #19: 'amp_17q12' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
AMP PEAK 19(17Q12) MUTATED 150 20 0.0 - 130.7 (20.0)
AMP PEAK 19(17Q12) WILD-TYPE 433 95 0.0 - 140.4 (19.0)

Figure S88.  Get High-res Image Gene #19: 'amp_17q12' versus Clinical Feature #1: 'Time to Death'

'amp_17q12' versus 'PATHOLOGY_M_STAGE'

P value = 0.00413 (Fisher's exact test), Q value = 0.027

Table S89.  Gene #19: 'amp_17q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 19(17Q12) MUTATED 102 33
AMP PEAK 19(17Q12) WILD-TYPE 346 53

Figure S89.  Get High-res Image Gene #19: 'amp_17q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_17q12' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0485 (Fisher's exact test), Q value = 0.15

Table S90.  Gene #19: 'amp_17q12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 19(17Q12) MUTATED 108 2 16 6
AMP PEAK 19(17Q12) WILD-TYPE 331 3 20 23

Figure S90.  Get High-res Image Gene #19: 'amp_17q12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_17q24.1' versus 'Time to Death'

P value = 0.00349 (logrank test), Q value = 0.025

Table S91.  Gene #20: 'amp_17q24.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
AMP PEAK 20(17Q24.1) MUTATED 137 15 0.1 - 130.7 (20.3)
AMP PEAK 20(17Q24.1) WILD-TYPE 446 100 0.0 - 140.4 (19.0)

Figure S91.  Get High-res Image Gene #20: 'amp_17q24.1' versus Clinical Feature #1: 'Time to Death'

'amp_17q24.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0905 (Fisher's exact test), Q value = 0.23

Table S92.  Gene #20: 'amp_17q24.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 20(17Q24.1) MUTATED 95 26
AMP PEAK 20(17Q24.1) WILD-TYPE 353 60

Figure S92.  Get High-res Image Gene #20: 'amp_17q24.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_17q24.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0865 (Fisher's exact test), Q value = 0.23

Table S93.  Gene #20: 'amp_17q24.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 20(17Q24.1) MUTATED 92 10 38 0
AMP PEAK 20(17Q24.1) WILD-TYPE 289 50 108 13

Figure S93.  Get High-res Image Gene #20: 'amp_17q24.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_19p13.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0506 (Fisher's exact test), Q value = 0.16

Table S94.  Gene #21: 'amp_19p13.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 21(19P13.2) MUTATED 67 8 36 0
AMP PEAK 21(19P13.2) WILD-TYPE 314 52 110 13

Figure S94.  Get High-res Image Gene #21: 'amp_19p13.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_19q12' versus 'PATHOLOGY_M_STAGE'

P value = 0.0148 (Fisher's exact test), Q value = 0.07

Table S95.  Gene #22: 'amp_19q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 22(19Q12) MUTATED 89 28
AMP PEAK 22(19Q12) WILD-TYPE 359 58

Figure S95.  Get High-res Image Gene #22: 'amp_19q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_19q12' versus 'HISTOLOGICAL_TYPE'

P value = 0.0196 (Fisher's exact test), Q value = 0.086

Table S96.  Gene #22: 'amp_19q12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 22(19Q12) MUTATED 84 10 44 0
AMP PEAK 22(19Q12) WILD-TYPE 297 50 102 13

Figure S96.  Get High-res Image Gene #22: 'amp_19q12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20p12.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00375 (Fisher's exact test), Q value = 0.026

Table S97.  Gene #23: 'amp_20p12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 23(20P12.1) MUTATED 50 1 10 68 4 1 10 13 30 24 42 14 1
AMP PEAK 23(20P12.1) WILD-TYPE 54 0 26 103 6 2 16 8 49 30 19 13 1

Figure S97.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_20p12.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.089 (Fisher's exact test), Q value = 0.23

Table S98.  Gene #23: 'amp_20p12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 23(20P12.1) MUTATED 142 75 58
AMP PEAK 23(20P12.1) WILD-TYPE 200 74 56

Figure S98.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_20p12.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.000343 (Fisher's exact test), Q value = 0.004

Table S99.  Gene #23: 'amp_20p12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 23(20P12.1) MUTATED 185 54
AMP PEAK 23(20P12.1) WILD-TYPE 263 32

Figure S99.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_20p12.1' versus 'GENDER'

P value = 0.0339 (Fisher's exact test), Q value = 0.12

Table S100.  Gene #23: 'amp_20p12.1' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
AMP PEAK 23(20P12.1) MUTATED 117 160
AMP PEAK 23(20P12.1) WILD-TYPE 169 162

Figure S100.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #8: 'GENDER'

'amp_20p12.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0115 (Fisher's exact test), Q value = 0.06

Table S101.  Gene #23: 'amp_20p12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 23(20P12.1) MUTATED 174 18 76 3
AMP PEAK 23(20P12.1) WILD-TYPE 207 42 70 10

Figure S101.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20p12.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0869 (Fisher's exact test), Q value = 0.23

Table S102.  Gene #23: 'amp_20p12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
AMP PEAK 23(20P12.1) MUTATED 7 270
AMP PEAK 23(20P12.1) WILD-TYPE 2 329

Figure S102.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'amp_20p12.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0726 (Fisher's exact test), Q value = 0.21

Table S103.  Gene #23: 'amp_20p12.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 23(20P12.1) MUTATED 197 3 23 10
AMP PEAK 23(20P12.1) WILD-TYPE 242 2 13 19

Figure S103.  Get High-res Image Gene #23: 'amp_20p12.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_20p11.21' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.00883 (Fisher's exact test), Q value = 0.051

Table S104.  Gene #24: 'amp_20p11.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 24(20P11.21) MUTATED 247 110
AMP PEAK 24(20P11.21) WILD-TYPE 195 52

Figure S104.  Get High-res Image Gene #24: 'amp_20p11.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_20p11.21' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0126 (Fisher's exact test), Q value = 0.062

Table S105.  Gene #24: 'amp_20p11.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 24(20P11.21) MUTATED 64 1 16 95 5 2 11 17 41 31 47 18 1
AMP PEAK 24(20P11.21) WILD-TYPE 40 0 20 76 5 1 15 4 38 23 14 9 1

Figure S105.  Get High-res Image Gene #24: 'amp_20p11.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_20p11.21' versus 'PATHOLOGY_M_STAGE'

P value = 0.00117 (Fisher's exact test), Q value = 0.01

Table S106.  Gene #24: 'amp_20p11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 24(20P11.21) MUTATED 248 64
AMP PEAK 24(20P11.21) WILD-TYPE 200 22

Figure S106.  Get High-res Image Gene #24: 'amp_20p11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_20p11.21' versus 'GENDER'

P value = 0.0827 (Fisher's exact test), Q value = 0.22

Table S107.  Gene #24: 'amp_20p11.21' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
AMP PEAK 24(20P11.21) MUTATED 158 201
AMP PEAK 24(20P11.21) WILD-TYPE 128 121

Figure S107.  Get High-res Image Gene #24: 'amp_20p11.21' versus Clinical Feature #8: 'GENDER'

'amp_20p11.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S108.  Gene #24: 'amp_20p11.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 24(20P11.21) MUTATED 224 22 105 4
AMP PEAK 24(20P11.21) WILD-TYPE 157 38 41 9

Figure S108.  Get High-res Image Gene #24: 'amp_20p11.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20q11.21' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 4.73e-06 (Fisher's exact test), Q value = 0.00026

Table S109.  Gene #25: 'amp_20q11.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 25(20Q11.21) MUTATED 316 144
AMP PEAK 25(20Q11.21) WILD-TYPE 126 18

Figure S109.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_20q11.21' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00064 (Fisher's exact test), Q value = 0.0061

Table S110.  Gene #25: 'amp_20q11.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 25(20Q11.21) MUTATED 79 1 21 117 5 3 19 20 63 45 55 23 1
AMP PEAK 25(20Q11.21) WILD-TYPE 25 0 15 54 5 0 7 1 16 9 6 4 1

Figure S110.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_20q11.21' versus 'PATHOLOGY_N_STAGE'

P value = 0.00055 (Fisher's exact test), Q value = 0.0056

Table S111.  Gene #25: 'amp_20q11.21' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 25(20Q11.21) MUTATED 240 127 93
AMP PEAK 25(20Q11.21) WILD-TYPE 102 22 21

Figure S111.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_20q11.21' versus 'PATHOLOGY_M_STAGE'

P value = 0.00344 (Fisher's exact test), Q value = 0.025

Table S112.  Gene #25: 'amp_20q11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 25(20Q11.21) MUTATED 331 76
AMP PEAK 25(20Q11.21) WILD-TYPE 117 10

Figure S112.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_20q11.21' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S113.  Gene #25: 'amp_20q11.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 25(20Q11.21) MUTATED 289 26 135 7
AMP PEAK 25(20Q11.21) WILD-TYPE 92 34 11 6

Figure S113.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20q11.21' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0401 (Fisher's exact test), Q value = 0.13

Table S114.  Gene #25: 'amp_20q11.21' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 25(20Q11.21) MUTATED 332 4 32 17
AMP PEAK 25(20Q11.21) WILD-TYPE 107 1 4 12

Figure S114.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_20q11.21' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00271 (Wilcoxon-test), Q value = 0.02

Table S115.  Gene #25: 'amp_20q11.21' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 25(20Q11.21) MUTATED 441 2.3 (4.7)
AMP PEAK 25(20Q11.21) WILD-TYPE 132 1.8 (4.8)

Figure S115.  Get High-res Image Gene #25: 'amp_20q11.21' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_20q12' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 2.44e-06 (Fisher's exact test), Q value = 0.00026

Table S116.  Gene #26: 'amp_20q12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 26(20Q12) MUTATED 317 145
AMP PEAK 26(20Q12) WILD-TYPE 125 17

Figure S116.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_20q12' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00024 (Fisher's exact test), Q value = 0.003

Table S117.  Gene #26: 'amp_20q12' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 26(20Q12) MUTATED 79 1 21 118 5 3 18 20 63 45 55 25 1
AMP PEAK 26(20Q12) WILD-TYPE 25 0 15 53 5 0 8 1 16 9 6 2 1

Figure S117.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_20q12' versus 'PATHOLOGY_N_STAGE'

P value = 0.00043 (Fisher's exact test), Q value = 0.0048

Table S118.  Gene #26: 'amp_20q12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 26(20Q12) MUTATED 241 128 93
AMP PEAK 26(20Q12) WILD-TYPE 101 21 21

Figure S118.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_20q12' versus 'PATHOLOGY_M_STAGE'

P value = 0.000445 (Fisher's exact test), Q value = 0.0049

Table S119.  Gene #26: 'amp_20q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 26(20Q12) MUTATED 331 78
AMP PEAK 26(20Q12) WILD-TYPE 117 8

Figure S119.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_20q12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S120.  Gene #26: 'amp_20q12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 26(20Q12) MUTATED 291 25 136 7
AMP PEAK 26(20Q12) WILD-TYPE 90 35 10 6

Figure S120.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20q12' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0393 (Fisher's exact test), Q value = 0.13

Table S121.  Gene #26: 'amp_20q12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 26(20Q12) MUTATED 333 4 32 17
AMP PEAK 26(20Q12) WILD-TYPE 106 1 4 12

Figure S121.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_20q12' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00283 (Wilcoxon-test), Q value = 0.021

Table S122.  Gene #26: 'amp_20q12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 26(20Q12) MUTATED 441 2.3 (4.7)
AMP PEAK 26(20Q12) WILD-TYPE 132 1.9 (4.9)

Figure S122.  Get High-res Image Gene #26: 'amp_20q12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'amp_20q13.31' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 3.78e-06 (Fisher's exact test), Q value = 0.00026

Table S123.  Gene #27: 'amp_20q13.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
AMP PEAK 27(20Q13.31) MUTATED 319 145
AMP PEAK 27(20Q13.31) WILD-TYPE 123 17

Figure S123.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'amp_20q13.31' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00044 (Fisher's exact test), Q value = 0.0049

Table S124.  Gene #27: 'amp_20q13.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
AMP PEAK 27(20Q13.31) MUTATED 79 1 22 119 5 3 19 20 63 46 56 24 1
AMP PEAK 27(20Q13.31) WILD-TYPE 25 0 14 52 5 0 7 1 16 8 5 3 1

Figure S124.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'amp_20q13.31' versus 'PATHOLOGY_N_STAGE'

P value = 0.00034 (Fisher's exact test), Q value = 0.004

Table S125.  Gene #27: 'amp_20q13.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
AMP PEAK 27(20Q13.31) MUTATED 243 128 94
AMP PEAK 27(20Q13.31) WILD-TYPE 99 21 20

Figure S125.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'amp_20q13.31' versus 'PATHOLOGY_M_STAGE'

P value = 7e-04 (Fisher's exact test), Q value = 0.0066

Table S126.  Gene #27: 'amp_20q13.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
AMP PEAK 27(20Q13.31) MUTATED 335 78
AMP PEAK 27(20Q13.31) WILD-TYPE 113 8

Figure S126.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'amp_20q13.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S127.  Gene #27: 'amp_20q13.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
AMP PEAK 27(20Q13.31) MUTATED 292 26 136 7
AMP PEAK 27(20Q13.31) WILD-TYPE 89 34 10 6

Figure S127.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'amp_20q13.31' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0385 (Fisher's exact test), Q value = 0.13

Table S128.  Gene #27: 'amp_20q13.31' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
AMP PEAK 27(20Q13.31) MUTATED 336 4 32 17
AMP PEAK 27(20Q13.31) WILD-TYPE 103 1 4 12

Figure S128.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'amp_20q13.31' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00257 (Wilcoxon-test), Q value = 0.02

Table S129.  Gene #27: 'amp_20q13.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
AMP PEAK 27(20Q13.31) MUTATED 444 2.3 (4.7)
AMP PEAK 27(20Q13.31) WILD-TYPE 129 1.8 (4.9)

Figure S129.  Get High-res Image Gene #27: 'amp_20q13.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_1p36.11' versus 'YEARS_TO_BIRTH'

P value = 0.0502 (Wilcoxon-test), Q value = 0.16

Table S130.  Gene #28: 'del_1p36.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 1(1P36.11) MUTATED 240 65.3 (11.8)
DEL PEAK 1(1P36.11) WILD-TYPE 366 66.9 (13.3)

Figure S130.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_1p36.11' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0903 (Fisher's exact test), Q value = 0.23

Table S131.  Gene #28: 'del_1p36.11' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 1(1P36.11) MUTATED 164 73
DEL PEAK 1(1P36.11) WILD-TYPE 278 89

Figure S131.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_1p36.11' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00349 (Fisher's exact test), Q value = 0.025

Table S132.  Gene #28: 'del_1p36.11' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 1(1P36.11) MUTATED 33 0 8 62 3 1 10 7 30 26 37 16 0
DEL PEAK 1(1P36.11) WILD-TYPE 71 1 28 109 7 2 16 14 49 28 24 11 2

Figure S132.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_1p36.11' versus 'PATHOLOGY_N_STAGE'

P value = 0.00228 (Fisher's exact test), Q value = 0.018

Table S133.  Gene #28: 'del_1p36.11' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 1(1P36.11) MUTATED 115 65 58
DEL PEAK 1(1P36.11) WILD-TYPE 227 84 56

Figure S133.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_1p36.11' versus 'PATHOLOGY_M_STAGE'

P value = 3.54e-05 (Fisher's exact test), Q value = 0.00078

Table S134.  Gene #28: 'del_1p36.11' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 1(1P36.11) MUTATED 161 52
DEL PEAK 1(1P36.11) WILD-TYPE 287 34

Figure S134.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_1p36.11' versus 'HISTOLOGICAL_TYPE'

P value = 0.00168 (Fisher's exact test), Q value = 0.014

Table S135.  Gene #28: 'del_1p36.11' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 1(1P36.11) MUTATED 152 11 65 7
DEL PEAK 1(1P36.11) WILD-TYPE 229 49 81 6

Figure S135.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_1p36.11' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0844 (Fisher's exact test), Q value = 0.22

Table S136.  Gene #28: 'del_1p36.11' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 1(1P36.11) MUTATED 163 2 21 12
DEL PEAK 1(1P36.11) WILD-TYPE 276 3 15 17

Figure S136.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_1p36.11' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000369 (Wilcoxon-test), Q value = 0.0042

Table S137.  Gene #28: 'del_1p36.11' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 1(1P36.11) MUTATED 225 3.1 (6.0)
DEL PEAK 1(1P36.11) WILD-TYPE 348 1.6 (3.5)

Figure S137.  Get High-res Image Gene #28: 'del_1p36.11' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_1p33' versus 'Time to Death'

P value = 0.0332 (logrank test), Q value = 0.12

Table S138.  Gene #29: 'del_1p33' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 2(1P33) MUTATED 166 41 0.0 - 129.3 (18.0)
DEL PEAK 2(1P33) WILD-TYPE 417 74 0.0 - 140.4 (19.1)

Figure S138.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #1: 'Time to Death'

'del_1p33' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0314 (Fisher's exact test), Q value = 0.12

Table S139.  Gene #29: 'del_1p33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 2(1P33) MUTATED 19 0 7 49 1 0 7 5 25 20 28 6 0
DEL PEAK 2(1P33) WILD-TYPE 85 1 29 122 9 3 19 16 54 34 33 21 2

Figure S139.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_1p33' versus 'PATHOLOGY_N_STAGE'

P value = 0.021 (Fisher's exact test), Q value = 0.09

Table S140.  Gene #29: 'del_1p33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 2(1P33) MUTATED 82 51 39
DEL PEAK 2(1P33) WILD-TYPE 260 98 75

Figure S140.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_1p33' versus 'PATHOLOGY_M_STAGE'

P value = 0.0132 (Fisher's exact test), Q value = 0.064

Table S141.  Gene #29: 'del_1p33' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 2(1P33) MUTATED 117 34
DEL PEAK 2(1P33) WILD-TYPE 331 52

Figure S141.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_1p33' versus 'HISTOLOGICAL_TYPE'

P value = 0.0299 (Fisher's exact test), Q value = 0.11

Table S142.  Gene #29: 'del_1p33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 2(1P33) MUTATED 110 10 49 1
DEL PEAK 2(1P33) WILD-TYPE 271 50 97 12

Figure S142.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_1p33' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00549 (Wilcoxon-test), Q value = 0.035

Table S143.  Gene #29: 'del_1p33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 2(1P33) MUTATED 162 3.1 (6.1)
DEL PEAK 2(1P33) WILD-TYPE 411 1.9 (4.0)

Figure S143.  Get High-res Image Gene #29: 'del_1p33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_1p13.2' versus 'Time to Death'

P value = 0.054 (logrank test), Q value = 0.17

Table S144.  Gene #30: 'del_1p13.2' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 3(1P13.2) MUTATED 165 39 0.2 - 131.5 (17.2)
DEL PEAK 3(1P13.2) WILD-TYPE 418 76 0.0 - 140.4 (19.4)

Figure S144.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #1: 'Time to Death'

'del_1p13.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00613 (Fisher's exact test), Q value = 0.038

Table S145.  Gene #30: 'del_1p13.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 3(1P13.2) MUTATED 19 0 8 47 1 2 5 4 24 21 29 6 0
DEL PEAK 3(1P13.2) WILD-TYPE 85 1 28 124 9 1 21 17 55 33 32 21 2

Figure S145.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_1p13.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.00722 (Fisher's exact test), Q value = 0.043

Table S146.  Gene #30: 'del_1p13.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 3(1P13.2) MUTATED 81 46 44
DEL PEAK 3(1P13.2) WILD-TYPE 261 103 70

Figure S146.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_1p13.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.00906 (Fisher's exact test), Q value = 0.052

Table S147.  Gene #30: 'del_1p13.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 3(1P13.2) MUTATED 118 35
DEL PEAK 3(1P13.2) WILD-TYPE 330 51

Figure S147.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_1p13.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.071 (Fisher's exact test), Q value = 0.2

Table S148.  Gene #30: 'del_1p13.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 3(1P13.2) MUTATED 108 10 49 2
DEL PEAK 3(1P13.2) WILD-TYPE 273 50 97 11

Figure S148.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_1p13.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000497 (Wilcoxon-test), Q value = 0.0053

Table S149.  Gene #30: 'del_1p13.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 3(1P13.2) MUTATED 161 3.2 (5.3)
DEL PEAK 3(1P13.2) WILD-TYPE 412 1.8 (4.4)

Figure S149.  Get High-res Image Gene #30: 'del_1p13.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_2p12' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.000623 (Fisher's exact test), Q value = 0.0061

Table S150.  Gene #31: 'del_2p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 4(2P12) MUTATED 8 13
DEL PEAK 4(2P12) WILD-TYPE 434 149

Figure S150.  Get High-res Image Gene #31: 'del_2p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_2p12' versus 'HISTOLOGICAL_TYPE'

P value = 0.00589 (Fisher's exact test), Q value = 0.037

Table S151.  Gene #31: 'del_2p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 4(2P12) MUTATED 8 0 11 1
DEL PEAK 4(2P12) WILD-TYPE 373 60 135 12

Figure S151.  Get High-res Image Gene #31: 'del_2p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_2q22.1' versus 'RACE'

P value = 0.0115 (Fisher's exact test), Q value = 0.06

Table S152.  Gene #32: 'del_2q22.1' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
DEL PEAK 5(2Q22.1) MUTATED 1 2 2 12
DEL PEAK 5(2Q22.1) WILD-TYPE 0 10 58 280

Figure S152.  Get High-res Image Gene #32: 'del_2q22.1' versus Clinical Feature #13: 'RACE'

'del_3p26.3' versus 'Time to Death'

P value = 0.0479 (logrank test), Q value = 0.15

Table S153.  Gene #33: 'del_3p26.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 6(3P26.3) MUTATED 86 18 0.2 - 85.0 (14.0)
DEL PEAK 6(3P26.3) WILD-TYPE 497 97 0.0 - 140.4 (20.0)

Figure S153.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #1: 'Time to Death'

'del_3p26.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.03 (Fisher's exact test), Q value = 0.11

Table S154.  Gene #33: 'del_3p26.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 6(3P26.3) MUTATED 8 0 3 24 0 1 5 2 14 8 19 5 0
DEL PEAK 6(3P26.3) WILD-TYPE 96 1 33 147 10 2 21 19 65 46 42 22 2

Figure S154.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_3p26.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0821 (Fisher's exact test), Q value = 0.22

Table S155.  Gene #33: 'del_3p26.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 6(3P26.3) MUTATED 2 8 69 11
DEL PEAK 6(3P26.3) WILD-TYPE 18 99 344 55

Figure S155.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_3p26.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0109 (Fisher's exact test), Q value = 0.059

Table S156.  Gene #33: 'del_3p26.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 6(3P26.3) MUTATED 38 28 24
DEL PEAK 6(3P26.3) WILD-TYPE 304 121 90

Figure S156.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_3p26.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.000707 (Fisher's exact test), Q value = 0.0066

Table S157.  Gene #33: 'del_3p26.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 6(3P26.3) MUTATED 55 24
DEL PEAK 6(3P26.3) WILD-TYPE 393 62

Figure S157.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_3p26.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.0589 (Fisher's exact test), Q value = 0.18

Table S158.  Gene #33: 'del_3p26.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 6(3P26.3) MUTATED 64 4 16 3
DEL PEAK 6(3P26.3) WILD-TYPE 317 56 130 10

Figure S158.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_3p26.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0636 (Fisher's exact test), Q value = 0.19

Table S159.  Gene #33: 'del_3p26.3' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 6(3P26.3) MUTATED 61 0 11 5
DEL PEAK 6(3P26.3) WILD-TYPE 378 5 25 24

Figure S159.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_3p26.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00536 (Wilcoxon-test), Q value = 0.034

Table S160.  Gene #33: 'del_3p26.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 6(3P26.3) MUTATED 84 3.5 (6.3)
DEL PEAK 6(3P26.3) WILD-TYPE 489 2.0 (4.3)

Figure S160.  Get High-res Image Gene #33: 'del_3p26.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_3p14.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.101 (Fisher's exact test), Q value = 0.25

Table S161.  Gene #34: 'del_3p14.2' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 7(3P14.2) MUTATED 7 15 78 16
DEL PEAK 7(3P14.2) WILD-TYPE 13 92 335 50

Figure S161.  Get High-res Image Gene #34: 'del_3p14.2' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_3p14.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.023 (Fisher's exact test), Q value = 0.095

Table S162.  Gene #34: 'del_3p14.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 7(3P14.2) MUTATED 76 24
DEL PEAK 7(3P14.2) WILD-TYPE 372 62

Figure S162.  Get High-res Image Gene #34: 'del_3p14.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_3p14.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0893 (Wilcoxon-test), Q value = 0.23

Table S163.  Gene #34: 'del_3p14.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 7(3P14.2) MUTATED 110 3.4 (6.3)
DEL PEAK 7(3P14.2) WILD-TYPE 463 2.0 (4.2)

Figure S163.  Get High-res Image Gene #34: 'del_3p14.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_3q26.31' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0327 (Fisher's exact test), Q value = 0.12

Table S164.  Gene #35: 'del_3q26.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 8(3Q26.31) MUTATED 5 0 1 21 0 1 3 0 6 9 12 4 0
DEL PEAK 8(3Q26.31) WILD-TYPE 99 1 35 150 10 2 23 21 73 45 49 23 2

Figure S164.  Get High-res Image Gene #35: 'del_3q26.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_3q26.31' versus 'PATHOLOGY_T_STAGE'

P value = 0.0977 (Fisher's exact test), Q value = 0.24

Table S165.  Gene #35: 'del_3q26.31' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 8(3Q26.31) MUTATED 0 6 47 9
DEL PEAK 8(3Q26.31) WILD-TYPE 20 101 366 57

Figure S165.  Get High-res Image Gene #35: 'del_3q26.31' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_3q26.31' versus 'PATHOLOGY_M_STAGE'

P value = 0.0326 (Fisher's exact test), Q value = 0.12

Table S166.  Gene #35: 'del_3q26.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 8(3Q26.31) MUTATED 41 15
DEL PEAK 8(3Q26.31) WILD-TYPE 407 71

Figure S166.  Get High-res Image Gene #35: 'del_3q26.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_3q26.31' versus 'HISTOLOGICAL_TYPE'

P value = 0.00946 (Fisher's exact test), Q value = 0.053

Table S167.  Gene #35: 'del_3q26.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 8(3Q26.31) MUTATED 41 3 11 5
DEL PEAK 8(3Q26.31) WILD-TYPE 340 57 135 8

Figure S167.  Get High-res Image Gene #35: 'del_3q26.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_4p16.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0614 (Fisher's exact test), Q value = 0.18

Table S168.  Gene #36: 'del_4p16.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 9(4P16.2) MUTATED 132 62
DEL PEAK 9(4P16.2) WILD-TYPE 310 100

Figure S168.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_4p16.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00267 (Fisher's exact test), Q value = 0.02

Table S169.  Gene #36: 'del_4p16.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 9(4P16.2) MUTATED 28 0 7 47 2 0 6 9 24 24 33 12 0
DEL PEAK 9(4P16.2) WILD-TYPE 76 1 29 124 8 3 20 12 55 30 28 15 2

Figure S169.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_4p16.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.00013 (Fisher's exact test), Q value = 0.0019

Table S170.  Gene #36: 'del_4p16.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 9(4P16.2) MUTATED 88 57 51
DEL PEAK 9(4P16.2) WILD-TYPE 254 92 63

Figure S170.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_4p16.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.000363 (Fisher's exact test), Q value = 0.0042

Table S171.  Gene #36: 'del_4p16.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 9(4P16.2) MUTATED 128 42
DEL PEAK 9(4P16.2) WILD-TYPE 320 44

Figure S171.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_4p16.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0313 (Fisher's exact test), Q value = 0.12

Table S172.  Gene #36: 'del_4p16.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 9(4P16.2) MUTATED 121 11 57 4
DEL PEAK 9(4P16.2) WILD-TYPE 260 49 89 9

Figure S172.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_4p16.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 3.31e-05 (Fisher's exact test), Q value = 0.00075

Table S173.  Gene #36: 'del_4p16.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 9(4P16.2) MUTATED 9 187
DEL PEAK 9(4P16.2) WILD-TYPE 0 412

Figure S173.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_4p16.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0906 (Fisher's exact test), Q value = 0.23

Table S174.  Gene #36: 'del_4p16.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 9(4P16.2) MUTATED 142 0 16 6
DEL PEAK 9(4P16.2) WILD-TYPE 297 5 20 23

Figure S174.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_4p16.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 7.59e-05 (Wilcoxon-test), Q value = 0.0012

Table S175.  Gene #36: 'del_4p16.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 9(4P16.2) MUTATED 187 3.2 (5.5)
DEL PEAK 9(4P16.2) WILD-TYPE 386 1.7 (4.2)

Figure S175.  Get High-res Image Gene #36: 'del_4p16.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_4q22.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0166 (Fisher's exact test), Q value = 0.076

Table S176.  Gene #37: 'del_4q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 10(4Q22.1) MUTATED 144 70
DEL PEAK 10(4Q22.1) WILD-TYPE 298 92

Figure S176.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_4q22.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.02 (Fisher's exact test), Q value = 0.087

Table S177.  Gene #37: 'del_4q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 10(4Q22.1) MUTATED 26 0 11 57 2 1 5 9 36 28 26 11 1
DEL PEAK 10(4Q22.1) WILD-TYPE 78 1 25 114 8 2 21 12 43 26 35 16 1

Figure S177.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_4q22.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00015 (Fisher's exact test), Q value = 0.0022

Table S178.  Gene #37: 'del_4q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 10(4Q22.1) MUTATED 99 65 54
DEL PEAK 10(4Q22.1) WILD-TYPE 243 84 60

Figure S178.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_4q22.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.00364 (Fisher's exact test), Q value = 0.025

Table S179.  Gene #37: 'del_4q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 10(4Q22.1) MUTATED 133 11 65 4
DEL PEAK 10(4Q22.1) WILD-TYPE 248 49 81 9

Figure S179.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_4q22.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00156 (Fisher's exact test), Q value = 0.013

Table S180.  Gene #37: 'del_4q22.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 10(4Q22.1) MUTATED 8 210
DEL PEAK 10(4Q22.1) WILD-TYPE 1 389

Figure S180.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_4q22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 8.47e-05 (Wilcoxon-test), Q value = 0.0014

Table S181.  Gene #37: 'del_4q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 10(4Q22.1) MUTATED 206 3.1 (5.5)
DEL PEAK 10(4Q22.1) WILD-TYPE 367 1.7 (4.1)

Figure S181.  Get High-res Image Gene #37: 'del_4q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_4q35.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0871 (Fisher's exact test), Q value = 0.23

Table S182.  Gene #38: 'del_4q35.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 11(4Q35.1) MUTATED 154 69
DEL PEAK 11(4Q35.1) WILD-TYPE 288 93

Figure S182.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_4q35.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0457 (Fisher's exact test), Q value = 0.15

Table S183.  Gene #38: 'del_4q35.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 11(4Q35.1) MUTATED 31 0 9 61 1 1 9 8 33 30 29 10 1
DEL PEAK 11(4Q35.1) WILD-TYPE 73 1 27 110 9 2 17 13 46 24 32 17 1

Figure S183.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_4q35.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00057 (Fisher's exact test), Q value = 0.0057

Table S184.  Gene #38: 'del_4q35.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 11(4Q35.1) MUTATED 106 64 57
DEL PEAK 11(4Q35.1) WILD-TYPE 236 85 57

Figure S184.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_4q35.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.068 (Fisher's exact test), Q value = 0.2

Table S185.  Gene #38: 'del_4q35.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 11(4Q35.1) MUTATED 160 40
DEL PEAK 11(4Q35.1) WILD-TYPE 288 46

Figure S185.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_4q35.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0593 (Fisher's exact test), Q value = 0.18

Table S186.  Gene #38: 'del_4q35.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 11(4Q35.1) MUTATED 138 16 65 3
DEL PEAK 11(4Q35.1) WILD-TYPE 243 44 81 10

Figure S186.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_4q35.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00212 (Fisher's exact test), Q value = 0.017

Table S187.  Gene #38: 'del_4q35.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 11(4Q35.1) MUTATED 8 219
DEL PEAK 11(4Q35.1) WILD-TYPE 1 380

Figure S187.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_4q35.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000164 (Wilcoxon-test), Q value = 0.0023

Table S188.  Gene #38: 'del_4q35.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 11(4Q35.1) MUTATED 215 2.9 (5.0)
DEL PEAK 11(4Q35.1) WILD-TYPE 358 1.8 (4.5)

Figure S188.  Get High-res Image Gene #38: 'del_4q35.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_5q12.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0212 (Fisher's exact test), Q value = 0.09

Table S189.  Gene #39: 'del_5q12.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 12(5Q12.1) MUTATED 103 53
DEL PEAK 12(5Q12.1) WILD-TYPE 339 109

Figure S189.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_5q12.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0376 (Fisher's exact test), Q value = 0.13

Table S190.  Gene #39: 'del_5q12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 12(5Q12.1) MUTATED 25 0 7 34 1 1 5 9 18 19 19 13 1
DEL PEAK 12(5Q12.1) WILD-TYPE 79 1 29 137 9 2 21 12 61 35 42 14 1

Figure S190.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_5q12.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0225 (Fisher's exact test), Q value = 0.094

Table S191.  Gene #39: 'del_5q12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 12(5Q12.1) MUTATED 74 44 38
DEL PEAK 12(5Q12.1) WILD-TYPE 268 105 76

Figure S191.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_5q12.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0137 (Fisher's exact test), Q value = 0.065

Table S192.  Gene #39: 'del_5q12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 12(5Q12.1) MUTATED 102 31
DEL PEAK 12(5Q12.1) WILD-TYPE 346 55

Figure S192.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_5q12.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0104 (Fisher's exact test), Q value = 0.056

Table S193.  Gene #39: 'del_5q12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 12(5Q12.1) MUTATED 95 8 50 2
DEL PEAK 12(5Q12.1) WILD-TYPE 286 52 96 11

Figure S193.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_5q12.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.000115 (Fisher's exact test), Q value = 0.0018

Table S194.  Gene #39: 'del_5q12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 12(5Q12.1) MUTATED 8 148
DEL PEAK 12(5Q12.1) WILD-TYPE 1 451

Figure S194.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_5q12.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0113 (Wilcoxon-test), Q value = 0.06

Table S195.  Gene #39: 'del_5q12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 12(5Q12.1) MUTATED 150 3.0 (5.6)
DEL PEAK 12(5Q12.1) WILD-TYPE 423 1.9 (4.3)

Figure S195.  Get High-res Image Gene #39: 'del_5q12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_5q21.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0102 (Fisher's exact test), Q value = 0.056

Table S196.  Gene #40: 'del_5q21.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 13(5Q21.2) MUTATED 26 0 8 40 1 1 6 10 27 23 23 14 1
DEL PEAK 13(5Q21.2) WILD-TYPE 78 1 28 131 9 2 20 11 52 31 38 13 1

Figure S196.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_5q21.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.00078 (Fisher's exact test), Q value = 0.0072

Table S197.  Gene #40: 'del_5q21.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 13(5Q21.2) MUTATED 83 56 45
DEL PEAK 13(5Q21.2) WILD-TYPE 259 93 69

Figure S197.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_5q21.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0102 (Fisher's exact test), Q value = 0.056

Table S198.  Gene #40: 'del_5q21.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 13(5Q21.2) MUTATED 124 36
DEL PEAK 13(5Q21.2) WILD-TYPE 324 50

Figure S198.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_5q21.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0534 (Fisher's exact test), Q value = 0.16

Table S199.  Gene #40: 'del_5q21.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 13(5Q21.2) MUTATED 116 13 53 1
DEL PEAK 13(5Q21.2) WILD-TYPE 265 47 93 12

Figure S199.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_5q21.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00042 (Fisher's exact test), Q value = 0.0047

Table S200.  Gene #40: 'del_5q21.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 13(5Q21.2) MUTATED 8 176
DEL PEAK 13(5Q21.2) WILD-TYPE 1 423

Figure S200.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_5q21.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00097 (Wilcoxon-test), Q value = 0.0088

Table S201.  Gene #40: 'del_5q21.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 13(5Q21.2) MUTATED 177 2.8 (4.9)
DEL PEAK 13(5Q21.2) WILD-TYPE 396 2.0 (4.6)

Figure S201.  Get High-res Image Gene #40: 'del_5q21.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_5q22.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.074 (Fisher's exact test), Q value = 0.21

Table S202.  Gene #41: 'del_5q22.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 14(5Q22.2) MUTATED 127 59
DEL PEAK 14(5Q22.2) WILD-TYPE 315 103

Figure S202.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_5q22.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0511 (Fisher's exact test), Q value = 0.16

Table S203.  Gene #41: 'del_5q22.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 14(5Q22.2) MUTATED 27 0 9 44 0 1 6 9 26 22 23 13 1
DEL PEAK 14(5Q22.2) WILD-TYPE 77 1 27 127 10 2 20 12 53 32 38 14 1

Figure S203.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_5q22.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0236 (Fisher's exact test), Q value = 0.097

Table S204.  Gene #41: 'del_5q22.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 14(5Q22.2) MUTATED 90 53 43
DEL PEAK 14(5Q22.2) WILD-TYPE 252 96 71

Figure S204.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_5q22.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0201 (Fisher's exact test), Q value = 0.087

Table S205.  Gene #41: 'del_5q22.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 14(5Q22.2) MUTATED 124 35
DEL PEAK 14(5Q22.2) WILD-TYPE 324 51

Figure S205.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_5q22.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.036 (Fisher's exact test), Q value = 0.12

Table S206.  Gene #41: 'del_5q22.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 14(5Q22.2) MUTATED 115 12 56 2
DEL PEAK 14(5Q22.2) WILD-TYPE 266 48 90 11

Figure S206.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_5q22.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.000457 (Fisher's exact test), Q value = 0.0049

Table S207.  Gene #41: 'del_5q22.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 14(5Q22.2) MUTATED 8 178
DEL PEAK 14(5Q22.2) WILD-TYPE 1 421

Figure S207.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_5q22.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0152 (Wilcoxon-test), Q value = 0.07

Table S208.  Gene #41: 'del_5q22.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 14(5Q22.2) MUTATED 177 2.7 (4.9)
DEL PEAK 14(5Q22.2) WILD-TYPE 396 2.0 (4.6)

Figure S208.  Get High-res Image Gene #41: 'del_5q22.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_6p25.3' versus 'YEARS_TO_BIRTH'

P value = 0.0617 (Wilcoxon-test), Q value = 0.18

Table S209.  Gene #42: 'del_6p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 15(6P25.3) MUTATED 78 68.7 (12.3)
DEL PEAK 15(6P25.3) WILD-TYPE 528 65.9 (12.8)

Figure S209.  Get High-res Image Gene #42: 'del_6p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_6p25.3' versus 'GENDER'

P value = 0.0687 (Fisher's exact test), Q value = 0.2

Table S210.  Gene #42: 'del_6p25.3' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
DEL PEAK 15(6P25.3) MUTATED 29 49
DEL PEAK 15(6P25.3) WILD-TYPE 257 273

Figure S210.  Get High-res Image Gene #42: 'del_6p25.3' versus Clinical Feature #8: 'GENDER'

'del_6p25.3' versus 'RACE'

P value = 0.00292 (Fisher's exact test), Q value = 0.021

Table S211.  Gene #42: 'del_6p25.3' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
DEL PEAK 15(6P25.3) MUTATED 0 4 1 38
DEL PEAK 15(6P25.3) WILD-TYPE 1 8 59 254

Figure S211.  Get High-res Image Gene #42: 'del_6p25.3' versus Clinical Feature #13: 'RACE'

'del_6q26' versus 'Time to Death'

P value = 0.0173 (logrank test), Q value = 0.078

Table S212.  Gene #43: 'del_6q26' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 16(6Q26) MUTATED 85 23 0.2 - 131.5 (17.0)
DEL PEAK 16(6Q26) WILD-TYPE 498 92 0.0 - 140.4 (19.8)

Figure S212.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #1: 'Time to Death'

'del_6q26' versus 'PATHOLOGY_N_STAGE'

P value = 0.00134 (Fisher's exact test), Q value = 0.012

Table S213.  Gene #43: 'del_6q26' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 16(6Q26) MUTATED 42 18 30
DEL PEAK 16(6Q26) WILD-TYPE 300 131 84

Figure S213.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_6q26' versus 'PATHOLOGY_M_STAGE'

P value = 0.0663 (Fisher's exact test), Q value = 0.19

Table S214.  Gene #43: 'del_6q26' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 16(6Q26) MUTATED 59 18
DEL PEAK 16(6Q26) WILD-TYPE 389 68

Figure S214.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_6q26' versus 'HISTOLOGICAL_TYPE'

P value = 0.0371 (Fisher's exact test), Q value = 0.13

Table S215.  Gene #43: 'del_6q26' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 16(6Q26) MUTATED 53 8 22 6
DEL PEAK 16(6Q26) WILD-TYPE 328 52 124 7

Figure S215.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_6q26' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00229 (Wilcoxon-test), Q value = 0.018

Table S216.  Gene #43: 'del_6q26' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 16(6Q26) MUTATED 85 3.8 (6.0)
DEL PEAK 16(6Q26) WILD-TYPE 488 2.0 (4.4)

Figure S216.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_6q26' versus 'RACE'

P value = 0.0171 (Fisher's exact test), Q value = 0.078

Table S217.  Gene #43: 'del_6q26' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
DEL PEAK 16(6Q26) MUTATED 1 4 5 39
DEL PEAK 16(6Q26) WILD-TYPE 0 8 55 253

Figure S217.  Get High-res Image Gene #43: 'del_6q26' versus Clinical Feature #13: 'RACE'

'del_8p23.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 7.19e-05 (Fisher's exact test), Q value = 0.0012

Table S218.  Gene #45: 'del_8p23.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 18(8P23.2) MUTATED 186 98
DEL PEAK 18(8P23.2) WILD-TYPE 256 64

Figure S218.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_8p23.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00012 (Fisher's exact test), Q value = 0.0018

Table S219.  Gene #45: 'del_8p23.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 18(8P23.2) MUTATED 40 0 12 64 3 2 14 11 43 33 44 14 1
DEL PEAK 18(8P23.2) WILD-TYPE 64 1 24 107 7 1 12 10 36 21 17 13 1

Figure S219.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_8p23.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.0742 (Fisher's exact test), Q value = 0.21

Table S220.  Gene #45: 'del_8p23.2' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 18(8P23.2) MUTATED 4 48 201 33
DEL PEAK 18(8P23.2) WILD-TYPE 16 59 212 33

Figure S220.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_8p23.2' versus 'PATHOLOGY_N_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S221.  Gene #45: 'del_8p23.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 18(8P23.2) MUTATED 132 80 72
DEL PEAK 18(8P23.2) WILD-TYPE 210 69 42

Figure S221.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_8p23.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.000154 (Fisher's exact test), Q value = 0.0022

Table S222.  Gene #45: 'del_8p23.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 18(8P23.2) MUTATED 197 57
DEL PEAK 18(8P23.2) WILD-TYPE 251 29

Figure S222.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_8p23.2' versus 'GENDER'

P value = 0.0283 (Fisher's exact test), Q value = 0.11

Table S223.  Gene #45: 'del_8p23.2' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
DEL PEAK 18(8P23.2) MUTATED 121 165
DEL PEAK 18(8P23.2) WILD-TYPE 165 157

Figure S223.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #8: 'GENDER'

'del_8p23.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S224.  Gene #45: 'del_8p23.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 18(8P23.2) MUTATED 169 16 89 7
DEL PEAK 18(8P23.2) WILD-TYPE 212 44 57 6

Figure S224.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_8p23.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0912 (Fisher's exact test), Q value = 0.23

Table S225.  Gene #45: 'del_8p23.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 18(8P23.2) MUTATED 7 279
DEL PEAK 18(8P23.2) WILD-TYPE 2 320

Figure S225.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_8p23.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00979 (Fisher's exact test), Q value = 0.055

Table S226.  Gene #45: 'del_8p23.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 18(8P23.2) MUTATED 198 2 25 9
DEL PEAK 18(8P23.2) WILD-TYPE 241 3 11 20

Figure S226.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_8p23.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 5.45e-06 (Wilcoxon-test), Q value = 0.00026

Table S227.  Gene #45: 'del_8p23.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 18(8P23.2) MUTATED 273 3.0 (5.8)
DEL PEAK 18(8P23.2) WILD-TYPE 300 1.5 (3.4)

Figure S227.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_8p22' versus 'Time to Death'

P value = 0.0943 (logrank test), Q value = 0.24

Table S228.  Gene #46: 'del_8p22' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 19(8P22) MUTATED 287 65 0.0 - 140.4 (19.0)
DEL PEAK 19(8P22) WILD-TYPE 296 50 0.0 - 139.2 (19.1)

Figure S228.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #1: 'Time to Death'

'del_8p22' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.000917 (Fisher's exact test), Q value = 0.0084

Table S229.  Gene #46: 'del_8p22' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 19(8P22) MUTATED 199 98
DEL PEAK 19(8P22) WILD-TYPE 243 64

Figure S229.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_8p22' versus 'NEOPLASM_DISEASESTAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S230.  Gene #46: 'del_8p22' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 19(8P22) MUTATED 40 0 13 66 3 2 14 13 45 36 44 17 1
DEL PEAK 19(8P22) WILD-TYPE 64 1 23 105 7 1 12 8 34 18 17 10 1

Figure S230.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_8p22' versus 'PATHOLOGY_T_STAGE'

P value = 0.0274 (Fisher's exact test), Q value = 0.11

Table S231.  Gene #46: 'del_8p22' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 19(8P22) MUTATED 4 48 211 36
DEL PEAK 19(8P22) WILD-TYPE 16 59 202 30

Figure S231.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_8p22' versus 'PATHOLOGY_N_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S232.  Gene #46: 'del_8p22' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 19(8P22) MUTATED 136 83 78
DEL PEAK 19(8P22) WILD-TYPE 206 66 36

Figure S232.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_8p22' versus 'PATHOLOGY_M_STAGE'

P value = 5.51e-05 (Fisher's exact test), Q value = 0.001

Table S233.  Gene #46: 'del_8p22' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 19(8P22) MUTATED 206 60
DEL PEAK 19(8P22) WILD-TYPE 242 26

Figure S233.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_8p22' versus 'HISTOLOGICAL_TYPE'

P value = 0.00018 (Fisher's exact test), Q value = 0.0024

Table S234.  Gene #46: 'del_8p22' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 19(8P22) MUTATED 181 17 89 7
DEL PEAK 19(8P22) WILD-TYPE 200 43 57 6

Figure S234.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_8p22' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.102 (Fisher's exact test), Q value = 0.25

Table S235.  Gene #46: 'del_8p22' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 19(8P22) MUTATED 7 292
DEL PEAK 19(8P22) WILD-TYPE 2 307

Figure S235.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_8p22' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0061 (Fisher's exact test), Q value = 0.038

Table S236.  Gene #46: 'del_8p22' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 19(8P22) MUTATED 211 2 25 8
DEL PEAK 19(8P22) WILD-TYPE 228 3 11 21

Figure S236.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_8p22' versus 'NUMBER_OF_LYMPH_NODES'

P value = 1.06e-07 (Wilcoxon-test), Q value = 3.4e-05

Table S237.  Gene #46: 'del_8p22' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 19(8P22) MUTATED 287 3.0 (5.7)
DEL PEAK 19(8P22) WILD-TYPE 286 1.4 (3.3)

Figure S237.  Get High-res Image Gene #46: 'del_8p22' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_8q11.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0628 (Fisher's exact test), Q value = 0.19

Table S238.  Gene #47: 'del_8q11.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 20(8Q11.1) MUTATED 19 16 12
DEL PEAK 20(8Q11.1) WILD-TYPE 323 133 102

Figure S238.  Get High-res Image Gene #47: 'del_8q11.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_8q11.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.085 (Fisher's exact test), Q value = 0.23

Table S239.  Gene #47: 'del_8q11.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 20(8Q11.1) MUTATED 32 11
DEL PEAK 20(8Q11.1) WILD-TYPE 416 75

Figure S239.  Get High-res Image Gene #47: 'del_8q11.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_8q11.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0272 (Wilcoxon-test), Q value = 0.11

Table S240.  Gene #47: 'del_8q11.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 20(8Q11.1) MUTATED 47 2.7 (3.8)
DEL PEAK 20(8Q11.1) WILD-TYPE 526 2.2 (4.8)

Figure S240.  Get High-res Image Gene #47: 'del_8q11.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_8q11.1' versus 'RACE'

P value = 0.0828 (Fisher's exact test), Q value = 0.22

Table S241.  Gene #47: 'del_8q11.1' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
DEL PEAK 20(8Q11.1) MUTATED 1 0 6 22
DEL PEAK 20(8Q11.1) WILD-TYPE 0 12 54 270

Figure S241.  Get High-res Image Gene #47: 'del_8q11.1' versus Clinical Feature #13: 'RACE'

'del_9p24.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0607 (Fisher's exact test), Q value = 0.18

Table S242.  Gene #48: 'del_9p24.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 21(9P24.2) MUTATED 57 18
DEL PEAK 21(9P24.2) WILD-TYPE 391 68

Figure S242.  Get High-res Image Gene #48: 'del_9p24.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_9p24.2' versus 'GENDER'

P value = 0.0437 (Fisher's exact test), Q value = 0.14

Table S243.  Gene #48: 'del_9p24.2' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
DEL PEAK 21(9P24.2) MUTATED 30 52
DEL PEAK 21(9P24.2) WILD-TYPE 256 270

Figure S243.  Get High-res Image Gene #48: 'del_9p24.2' versus Clinical Feature #8: 'GENDER'

'del_9p24.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0337 (Wilcoxon-test), Q value = 0.12

Table S244.  Gene #48: 'del_9p24.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 21(9P24.2) MUTATED 76 2.8 (5.0)
DEL PEAK 21(9P24.2) WILD-TYPE 497 2.1 (4.7)

Figure S244.  Get High-res Image Gene #48: 'del_9p24.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_10p15.3' versus 'YEARS_TO_BIRTH'

P value = 0.0334 (Wilcoxon-test), Q value = 0.12

Table S245.  Gene #49: 'del_10p15.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 22(10P15.3) MUTATED 112 63.8 (13.2)
DEL PEAK 22(10P15.3) WILD-TYPE 494 66.8 (12.6)

Figure S245.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_10p15.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0426 (Fisher's exact test), Q value = 0.14

Table S246.  Gene #49: 'del_10p15.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 22(10P15.3) MUTATED 19 0 6 21 0 1 2 7 15 13 17 7 1
DEL PEAK 22(10P15.3) WILD-TYPE 85 1 30 150 10 2 24 14 64 41 44 20 1

Figure S246.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_10p15.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0229 (Fisher's exact test), Q value = 0.095

Table S247.  Gene #49: 'del_10p15.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 22(10P15.3) MUTATED 51 32 29
DEL PEAK 22(10P15.3) WILD-TYPE 291 117 85

Figure S247.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_10p15.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.0243 (Fisher's exact test), Q value = 0.099

Table S248.  Gene #49: 'del_10p15.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 22(10P15.3) MUTATED 77 24
DEL PEAK 22(10P15.3) WILD-TYPE 371 62

Figure S248.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_10p15.3' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0131 (Fisher's exact test), Q value = 0.064

Table S249.  Gene #49: 'del_10p15.3' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 22(10P15.3) MUTATED 5 107
DEL PEAK 22(10P15.3) WILD-TYPE 4 492

Figure S249.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_10p15.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00405 (Wilcoxon-test), Q value = 0.027

Table S250.  Gene #49: 'del_10p15.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 22(10P15.3) MUTATED 108 3.2 (6.5)
DEL PEAK 22(10P15.3) WILD-TYPE 465 2.0 (4.2)

Figure S250.  Get High-res Image Gene #49: 'del_10p15.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_10q21.1' versus 'YEARS_TO_BIRTH'

P value = 0.034 (Wilcoxon-test), Q value = 0.12

Table S251.  Gene #50: 'del_10q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 23(10Q21.1) MUTATED 135 64.1 (12.9)
DEL PEAK 23(10Q21.1) WILD-TYPE 471 66.9 (12.6)

Figure S251.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_10q21.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0955 (Fisher's exact test), Q value = 0.24

Table S252.  Gene #50: 'del_10q21.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 23(10Q21.1) MUTATED 20 0 7 31 1 1 2 7 18 19 19 6 1
DEL PEAK 23(10Q21.1) WILD-TYPE 84 1 29 140 9 2 24 14 61 35 42 21 1

Figure S252.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_10q21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0802 (Fisher's exact test), Q value = 0.22

Table S253.  Gene #50: 'del_10q21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 23(10Q21.1) MUTATED 66 36 33
DEL PEAK 23(10Q21.1) WILD-TYPE 276 113 81

Figure S253.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_10q21.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0386 (Fisher's exact test), Q value = 0.13

Table S254.  Gene #50: 'del_10q21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 23(10Q21.1) MUTATED 87 7 34 6
DEL PEAK 23(10Q21.1) WILD-TYPE 294 53 112 7

Figure S254.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_10q21.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0292 (Fisher's exact test), Q value = 0.11

Table S255.  Gene #50: 'del_10q21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 23(10Q21.1) MUTATED 5 130
DEL PEAK 23(10Q21.1) WILD-TYPE 4 469

Figure S255.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_10q21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0248 (Wilcoxon-test), Q value = 0.1

Table S256.  Gene #50: 'del_10q21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 23(10Q21.1) MUTATED 130 2.9 (6.1)
DEL PEAK 23(10Q21.1) WILD-TYPE 443 2.0 (4.2)

Figure S256.  Get High-res Image Gene #50: 'del_10q21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_10q23.31' versus 'YEARS_TO_BIRTH'

P value = 0.00383 (Wilcoxon-test), Q value = 0.026

Table S257.  Gene #51: 'del_10q23.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 24(10Q23.31) MUTATED 158 63.7 (12.7)
DEL PEAK 24(10Q23.31) WILD-TYPE 448 67.2 (12.6)

Figure S257.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_10q23.31' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0748 (Fisher's exact test), Q value = 0.21

Table S258.  Gene #51: 'del_10q23.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 24(10Q23.31) MUTATED 106 51
DEL PEAK 24(10Q23.31) WILD-TYPE 336 111

Figure S258.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_10q23.31' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0343 (Fisher's exact test), Q value = 0.12

Table S259.  Gene #51: 'del_10q23.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 24(10Q23.31) MUTATED 21 1 6 40 2 1 6 10 20 18 22 6 2
DEL PEAK 24(10Q23.31) WILD-TYPE 83 0 30 131 8 2 20 11 59 36 39 21 0

Figure S259.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_10q23.31' versus 'PATHOLOGY_N_STAGE'

P value = 0.0476 (Fisher's exact test), Q value = 0.15

Table S260.  Gene #51: 'del_10q23.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 24(10Q23.31) MUTATED 76 44 37
DEL PEAK 24(10Q23.31) WILD-TYPE 266 105 77

Figure S260.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_10q23.31' versus 'HISTOLOGICAL_TYPE'

P value = 0.0212 (Fisher's exact test), Q value = 0.09

Table S261.  Gene #51: 'del_10q23.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 24(10Q23.31) MUTATED 96 9 42 7
DEL PEAK 24(10Q23.31) WILD-TYPE 285 51 104 6

Figure S261.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_10q23.31' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0116 (Fisher's exact test), Q value = 0.06

Table S262.  Gene #51: 'del_10q23.31' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 24(10Q23.31) MUTATED 6 152
DEL PEAK 24(10Q23.31) WILD-TYPE 3 447

Figure S262.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_10q23.31' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00933 (Wilcoxon-test), Q value = 0.053

Table S263.  Gene #51: 'del_10q23.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 24(10Q23.31) MUTATED 151 2.5 (4.4)
DEL PEAK 24(10Q23.31) WILD-TYPE 422 2.1 (4.8)

Figure S263.  Get High-res Image Gene #51: 'del_10q23.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_10q25.2' versus 'YEARS_TO_BIRTH'

P value = 0.0427 (Wilcoxon-test), Q value = 0.14

Table S264.  Gene #52: 'del_10q25.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 25(10Q25.2) MUTATED 154 64.5 (12.7)
DEL PEAK 25(10Q25.2) WILD-TYPE 452 66.9 (12.7)

Figure S264.  Get High-res Image Gene #52: 'del_10q25.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_10q25.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0243 (Fisher's exact test), Q value = 0.099

Table S265.  Gene #52: 'del_10q25.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 25(10Q25.2) MUTATED 73 42 38
DEL PEAK 25(10Q25.2) WILD-TYPE 269 107 76

Figure S265.  Get High-res Image Gene #52: 'del_10q25.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_10q25.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0299 (Fisher's exact test), Q value = 0.11

Table S266.  Gene #52: 'del_10q25.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 25(10Q25.2) MUTATED 97 9 39 7
DEL PEAK 25(10Q25.2) WILD-TYPE 284 51 107 6

Figure S266.  Get High-res Image Gene #52: 'del_10q25.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_10q25.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0102 (Fisher's exact test), Q value = 0.056

Table S267.  Gene #52: 'del_10q25.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 25(10Q25.2) MUTATED 6 148
DEL PEAK 25(10Q25.2) WILD-TYPE 3 451

Figure S267.  Get High-res Image Gene #52: 'del_10q25.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_10q25.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0135 (Wilcoxon-test), Q value = 0.065

Table S268.  Gene #52: 'del_10q25.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 25(10Q25.2) MUTATED 148 2.6 (4.5)
DEL PEAK 25(10Q25.2) WILD-TYPE 425 2.1 (4.8)

Figure S268.  Get High-res Image Gene #52: 'del_10q25.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_11q22.3' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0711 (Fisher's exact test), Q value = 0.2

Table S269.  Gene #53: 'del_11q22.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 26(11Q22.3) MUTATED 70 36
DEL PEAK 26(11Q22.3) WILD-TYPE 372 126

Figure S269.  Get High-res Image Gene #53: 'del_11q22.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_11q22.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.0435 (Fisher's exact test), Q value = 0.14

Table S270.  Gene #53: 'del_11q22.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 26(11Q22.3) MUTATED 62 8 29 6
DEL PEAK 26(11Q22.3) WILD-TYPE 319 52 117 7

Figure S270.  Get High-res Image Gene #53: 'del_11q22.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_11q22.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.066 (Wilcoxon-test), Q value = 0.19

Table S271.  Gene #53: 'del_11q22.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 26(11Q22.3) MUTATED 106 3.1 (5.9)
DEL PEAK 26(11Q22.3) WILD-TYPE 467 2.0 (4.4)

Figure S271.  Get High-res Image Gene #53: 'del_11q22.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_12p13.1' versus 'Time to Death'

P value = 0.0454 (logrank test), Q value = 0.15

Table S272.  Gene #54: 'del_12p13.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 27(12P13.1) MUTATED 87 23 0.1 - 78.1 (16.4)
DEL PEAK 27(12P13.1) WILD-TYPE 496 92 0.0 - 140.4 (19.3)

Figure S272.  Get High-res Image Gene #54: 'del_12p13.1' versus Clinical Feature #1: 'Time to Death'

'del_12p13.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0264 (Fisher's exact test), Q value = 0.1

Table S273.  Gene #54: 'del_12p13.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 27(12P13.1) MUTATED 41 32 18
DEL PEAK 27(12P13.1) WILD-TYPE 301 117 96

Figure S273.  Get High-res Image Gene #54: 'del_12p13.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_12p13.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0284 (Fisher's exact test), Q value = 0.11

Table S274.  Gene #54: 'del_12p13.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 27(12P13.1) MUTATED 57 19
DEL PEAK 27(12P13.1) WILD-TYPE 391 67

Figure S274.  Get High-res Image Gene #54: 'del_12p13.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_12p13.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0159 (Fisher's exact test), Q value = 0.073

Table S275.  Gene #54: 'del_12p13.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 27(12P13.1) MUTATED 57 2 28 1
DEL PEAK 27(12P13.1) WILD-TYPE 324 58 118 12

Figure S275.  Get High-res Image Gene #54: 'del_12p13.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_12q21.33' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0711 (Fisher's exact test), Q value = 0.2

Table S276.  Gene #55: 'del_12q21.33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 28(12Q21.33) MUTATED 15 0 3 19 1 2 1 4 11 14 10 4 1
DEL PEAK 28(12Q21.33) WILD-TYPE 89 1 33 152 9 1 25 17 68 40 51 23 1

Figure S276.  Get High-res Image Gene #55: 'del_12q21.33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_12q21.33' versus 'PATHOLOGY_N_STAGE'

P value = 0.0785 (Fisher's exact test), Q value = 0.22

Table S277.  Gene #55: 'del_12q21.33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 28(12Q21.33) MUTATED 41 24 23
DEL PEAK 28(12Q21.33) WILD-TYPE 301 125 91

Figure S277.  Get High-res Image Gene #55: 'del_12q21.33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_12q21.33' versus 'HISTOLOGICAL_TYPE'

P value = 0.0282 (Fisher's exact test), Q value = 0.11

Table S278.  Gene #55: 'del_12q21.33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 28(12Q21.33) MUTATED 57 2 26 1
DEL PEAK 28(12Q21.33) WILD-TYPE 324 58 120 12

Figure S278.  Get High-res Image Gene #55: 'del_12q21.33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_12q21.33' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0192 (Wilcoxon-test), Q value = 0.085

Table S279.  Gene #55: 'del_12q21.33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 28(12Q21.33) MUTATED 85 2.9 (4.9)
DEL PEAK 28(12Q21.33) WILD-TYPE 488 2.1 (4.7)

Figure S279.  Get High-res Image Gene #55: 'del_12q21.33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_14q11.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0116 (Fisher's exact test), Q value = 0.06

Table S280.  Gene #56: 'del_14q11.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 29(14Q11.2) MUTATED 136 68
DEL PEAK 29(14Q11.2) WILD-TYPE 306 94

Figure S280.  Get High-res Image Gene #56: 'del_14q11.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_14q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.032 (Fisher's exact test), Q value = 0.12

Table S281.  Gene #56: 'del_14q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 29(14Q11.2) MUTATED 105 64 38
DEL PEAK 29(14Q11.2) WILD-TYPE 237 85 76

Figure S281.  Get High-res Image Gene #56: 'del_14q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_14q11.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0825 (Fisher's exact test), Q value = 0.22

Table S282.  Gene #56: 'del_14q11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 29(14Q11.2) MUTATED 147 37
DEL PEAK 29(14Q11.2) WILD-TYPE 301 49

Figure S282.  Get High-res Image Gene #56: 'del_14q11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_14q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S283.  Gene #56: 'del_14q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 29(14Q11.2) MUTATED 130 5 66 2
DEL PEAK 29(14Q11.2) WILD-TYPE 251 55 80 11

Figure S283.  Get High-res Image Gene #56: 'del_14q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_14q31.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0339 (Fisher's exact test), Q value = 0.12

Table S284.  Gene #57: 'del_14q31.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 30(14Q31.1) MUTATED 143 68
DEL PEAK 30(14Q31.1) WILD-TYPE 299 94

Figure S284.  Get High-res Image Gene #57: 'del_14q31.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_14q31.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.025 (Fisher's exact test), Q value = 0.1

Table S285.  Gene #57: 'del_14q31.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 30(14Q31.1) MUTATED 106 65 42
DEL PEAK 30(14Q31.1) WILD-TYPE 236 84 72

Figure S285.  Get High-res Image Gene #57: 'del_14q31.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_14q31.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.0193 (Fisher's exact test), Q value = 0.085

Table S286.  Gene #57: 'del_14q31.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 30(14Q31.1) MUTATED 151 41
DEL PEAK 30(14Q31.1) WILD-TYPE 297 45

Figure S286.  Get High-res Image Gene #57: 'del_14q31.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_14q31.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S287.  Gene #57: 'del_14q31.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 30(14Q31.1) MUTATED 137 5 65 1
DEL PEAK 30(14Q31.1) WILD-TYPE 244 55 81 12

Figure S287.  Get High-res Image Gene #57: 'del_14q31.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_14q31.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0401 (Wilcoxon-test), Q value = 0.13

Table S288.  Gene #57: 'del_14q31.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 30(14Q31.1) MUTATED 200 2.6 (5.1)
DEL PEAK 30(14Q31.1) WILD-TYPE 373 2.0 (4.5)

Figure S288.  Get High-res Image Gene #57: 'del_14q31.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_15q11.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0637 (Fisher's exact test), Q value = 0.19

Table S289.  Gene #58: 'del_15q11.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 31(15Q11.2) MUTATED 39 0 9 63 3 2 8 12 34 28 30 14 2
DEL PEAK 31(15Q11.2) WILD-TYPE 65 1 27 108 7 1 18 9 45 26 31 13 0

Figure S289.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_15q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0124 (Fisher's exact test), Q value = 0.062

Table S290.  Gene #58: 'del_15q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 31(15Q11.2) MUTATED 123 72 54
DEL PEAK 31(15Q11.2) WILD-TYPE 219 77 60

Figure S290.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_15q11.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.0235 (Fisher's exact test), Q value = 0.097

Table S291.  Gene #58: 'del_15q11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 31(15Q11.2) MUTATED 175 45
DEL PEAK 31(15Q11.2) WILD-TYPE 273 41

Figure S291.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_15q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0771 (Fisher's exact test), Q value = 0.21

Table S292.  Gene #58: 'del_15q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 31(15Q11.2) MUTATED 155 16 67 6
DEL PEAK 31(15Q11.2) WILD-TYPE 226 44 79 7

Figure S292.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_15q11.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0362 (Fisher's exact test), Q value = 0.12

Table S293.  Gene #58: 'del_15q11.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 31(15Q11.2) MUTATED 7 242
DEL PEAK 31(15Q11.2) WILD-TYPE 2 357

Figure S293.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_15q11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00313 (Wilcoxon-test), Q value = 0.023

Table S294.  Gene #58: 'del_15q11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 31(15Q11.2) MUTATED 234 2.7 (4.8)
DEL PEAK 31(15Q11.2) WILD-TYPE 339 1.9 (4.7)

Figure S294.  Get High-res Image Gene #58: 'del_15q11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_15q15.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0318 (Fisher's exact test), Q value = 0.12

Table S295.  Gene #59: 'del_15q15.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 32(15Q15.2) MUTATED 167 77
DEL PEAK 32(15Q15.2) WILD-TYPE 275 85

Figure S295.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_15q15.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0478 (Fisher's exact test), Q value = 0.15

Table S296.  Gene #59: 'del_15q15.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 32(15Q15.2) MUTATED 41 0 8 60 3 2 9 10 34 27 33 13 2
DEL PEAK 32(15Q15.2) WILD-TYPE 63 1 28 111 7 1 17 11 45 27 28 14 0

Figure S296.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_15q15.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0036 (Fisher's exact test), Q value = 0.025

Table S297.  Gene #59: 'del_15q15.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 32(15Q15.2) MUTATED 120 75 52
DEL PEAK 32(15Q15.2) WILD-TYPE 222 74 62

Figure S297.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_15q15.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.00397 (Fisher's exact test), Q value = 0.027

Table S298.  Gene #59: 'del_15q15.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 32(15Q15.2) MUTATED 169 47
DEL PEAK 32(15Q15.2) WILD-TYPE 279 39

Figure S298.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_15q15.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0189 (Fisher's exact test), Q value = 0.084

Table S299.  Gene #59: 'del_15q15.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 32(15Q15.2) MUTATED 151 15 70 6
DEL PEAK 32(15Q15.2) WILD-TYPE 230 45 76 7

Figure S299.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_15q15.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0353 (Fisher's exact test), Q value = 0.12

Table S300.  Gene #59: 'del_15q15.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 32(15Q15.2) MUTATED 7 240
DEL PEAK 32(15Q15.2) WILD-TYPE 2 359

Figure S300.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_15q15.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00193 (Wilcoxon-test), Q value = 0.015

Table S301.  Gene #59: 'del_15q15.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 32(15Q15.2) MUTATED 233 2.7 (4.9)
DEL PEAK 32(15Q15.2) WILD-TYPE 340 1.9 (4.6)

Figure S301.  Get High-res Image Gene #59: 'del_15q15.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_15q21.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0248 (Fisher's exact test), Q value = 0.1

Table S302.  Gene #60: 'del_15q21.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 33(15Q21.1) MUTATED 165 77
DEL PEAK 33(15Q21.1) WILD-TYPE 277 85

Figure S302.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_15q21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0153 (Fisher's exact test), Q value = 0.071

Table S303.  Gene #60: 'del_15q21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 33(15Q21.1) MUTATED 121 72 51
DEL PEAK 33(15Q21.1) WILD-TYPE 221 77 63

Figure S303.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_15q21.1' versus 'PATHOLOGY_M_STAGE'

P value = 0.00794 (Fisher's exact test), Q value = 0.046

Table S304.  Gene #60: 'del_15q21.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 33(15Q21.1) MUTATED 168 46
DEL PEAK 33(15Q21.1) WILD-TYPE 280 40

Figure S304.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_15q21.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0185 (Fisher's exact test), Q value = 0.083

Table S305.  Gene #60: 'del_15q21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 33(15Q21.1) MUTATED 149 15 70 6
DEL PEAK 33(15Q21.1) WILD-TYPE 232 45 76 7

Figure S305.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_15q21.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0342 (Fisher's exact test), Q value = 0.12

Table S306.  Gene #60: 'del_15q21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 33(15Q21.1) MUTATED 7 237
DEL PEAK 33(15Q21.1) WILD-TYPE 2 362

Figure S306.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_15q21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00699 (Wilcoxon-test), Q value = 0.042

Table S307.  Gene #60: 'del_15q21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 33(15Q21.1) MUTATED 230 2.7 (4.9)
DEL PEAK 33(15Q21.1) WILD-TYPE 343 1.9 (4.6)

Figure S307.  Get High-res Image Gene #60: 'del_15q21.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_15q22.33' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.018 (Fisher's exact test), Q value = 0.081

Table S308.  Gene #61: 'del_15q22.33' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 34(15Q22.33) MUTATED 156 75
DEL PEAK 34(15Q22.33) WILD-TYPE 286 87

Figure S308.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_15q22.33' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00597 (Fisher's exact test), Q value = 0.037

Table S309.  Gene #61: 'del_15q22.33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 34(15Q22.33) MUTATED 32 0 7 60 3 2 7 11 32 29 31 14 1
DEL PEAK 34(15Q22.33) WILD-TYPE 72 1 29 111 7 1 19 10 47 25 30 13 1

Figure S309.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_15q22.33' versus 'PATHOLOGY_T_STAGE'

P value = 0.0928 (Fisher's exact test), Q value = 0.23

Table S310.  Gene #61: 'del_15q22.33' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 34(15Q22.33) MUTATED 9 31 171 23
DEL PEAK 34(15Q22.33) WILD-TYPE 11 76 242 43

Figure S310.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_15q22.33' versus 'PATHOLOGY_N_STAGE'

P value = 0.00175 (Fisher's exact test), Q value = 0.014

Table S311.  Gene #61: 'del_15q22.33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 34(15Q22.33) MUTATED 111 69 54
DEL PEAK 34(15Q22.33) WILD-TYPE 231 80 60

Figure S311.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_15q22.33' versus 'PATHOLOGY_M_STAGE'

P value = 0.00509 (Fisher's exact test), Q value = 0.033

Table S312.  Gene #61: 'del_15q22.33' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 34(15Q22.33) MUTATED 159 45
DEL PEAK 34(15Q22.33) WILD-TYPE 289 41

Figure S312.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_15q22.33' versus 'HISTOLOGICAL_TYPE'

P value = 0.0128 (Fisher's exact test), Q value = 0.063

Table S313.  Gene #61: 'del_15q22.33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 34(15Q22.33) MUTATED 141 14 68 6
DEL PEAK 34(15Q22.33) WILD-TYPE 240 46 78 7

Figure S313.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_15q22.33' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.00267 (Fisher's exact test), Q value = 0.02

Table S314.  Gene #61: 'del_15q22.33' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 34(15Q22.33) MUTATED 8 226
DEL PEAK 34(15Q22.33) WILD-TYPE 1 373

Figure S314.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_15q22.33' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000523 (Wilcoxon-test), Q value = 0.0055

Table S315.  Gene #61: 'del_15q22.33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 34(15Q22.33) MUTATED 221 2.8 (4.9)
DEL PEAK 34(15Q22.33) WILD-TYPE 352 1.9 (4.6)

Figure S315.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_15q22.33' versus 'RACE'

P value = 0.0858 (Fisher's exact test), Q value = 0.23

Table S316.  Gene #61: 'del_15q22.33' versus Clinical Feature #13: 'RACE'

nPatients AMERICAN INDIAN OR ALASKA NATIVE ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 1 12 60 292
DEL PEAK 34(15Q22.33) MUTATED 1 2 20 124
DEL PEAK 34(15Q22.33) WILD-TYPE 0 10 40 168

Figure S316.  Get High-res Image Gene #61: 'del_15q22.33' versus Clinical Feature #13: 'RACE'

'del_16p13.3' versus 'Time to Death'

P value = 0.00336 (logrank test), Q value = 0.024

Table S317.  Gene #62: 'del_16p13.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 35(16P13.3) MUTATED 63 20 0.2 - 61.8 (18.2)
DEL PEAK 35(16P13.3) WILD-TYPE 520 95 0.0 - 140.4 (19.1)

Figure S317.  Get High-res Image Gene #62: 'del_16p13.3' versus Clinical Feature #1: 'Time to Death'

'del_16p13.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0118 (Fisher's exact test), Q value = 0.06

Table S318.  Gene #62: 'del_16p13.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 35(16P13.3) MUTATED 4 0 3 23 2 1 0 0 9 11 8 5 0
DEL PEAK 35(16P13.3) WILD-TYPE 100 1 33 148 8 2 26 21 70 43 53 22 2

Figure S318.  Get High-res Image Gene #62: 'del_16p13.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_16p13.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0558 (Fisher's exact test), Q value = 0.17

Table S319.  Gene #62: 'del_16p13.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 35(16P13.3) MUTATED 0 6 54 7
DEL PEAK 35(16P13.3) WILD-TYPE 20 101 359 59

Figure S319.  Get High-res Image Gene #62: 'del_16p13.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_16q23.1' versus 'Time to Death'

P value = 0.0263 (logrank test), Q value = 0.1

Table S320.  Gene #63: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 36(16Q23.1) MUTATED 77 19 0.5 - 129.3 (17.9)
DEL PEAK 36(16Q23.1) WILD-TYPE 506 96 0.0 - 140.4 (19.3)

Figure S320.  Get High-res Image Gene #63: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'

'del_17p12' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.00203 (Fisher's exact test), Q value = 0.016

Table S321.  Gene #64: 'del_17p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 37(17P12) MUTATED 247 113
DEL PEAK 37(17P12) WILD-TYPE 195 49

Figure S321.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_17p12' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00021 (Fisher's exact test), Q value = 0.0027

Table S322.  Gene #64: 'del_17p12' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 37(17P12) MUTATED 53 0 19 87 3 1 16 16 52 42 45 20 2
DEL PEAK 37(17P12) WILD-TYPE 51 1 17 84 7 2 10 5 27 12 16 7 0

Figure S322.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_17p12' versus 'PATHOLOGY_N_STAGE'

P value = 5e-05 (Fisher's exact test), Q value = 0.00099

Table S323.  Gene #64: 'del_17p12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 37(17P12) MUTATED 177 102 83
DEL PEAK 37(17P12) WILD-TYPE 165 47 31

Figure S323.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_17p12' versus 'PATHOLOGY_M_STAGE'

P value = 0.00169 (Fisher's exact test), Q value = 0.014

Table S324.  Gene #64: 'del_17p12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 37(17P12) MUTATED 258 65
DEL PEAK 37(17P12) WILD-TYPE 190 21

Figure S324.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_17p12' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S325.  Gene #64: 'del_17p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 37(17P12) MUTATED 229 17 105 6
DEL PEAK 37(17P12) WILD-TYPE 152 43 41 7

Figure S325.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_17p12' versus 'NUMBER_OF_LYMPH_NODES'

P value = 7.41e-06 (Wilcoxon-test), Q value = 0.00026

Table S326.  Gene #64: 'del_17p12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 37(17P12) MUTATED 343 2.7 (5.2)
DEL PEAK 37(17P12) WILD-TYPE 230 1.5 (3.8)

Figure S326.  Get High-res Image Gene #64: 'del_17p12' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_17q24.3' versus 'Time to Death'

P value = 0.0898 (logrank test), Q value = 0.23

Table S327.  Gene #65: 'del_17q24.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 38(17Q24.3) MUTATED 92 23 0.2 - 140.4 (17.1)
DEL PEAK 38(17Q24.3) WILD-TYPE 491 92 0.0 - 139.2 (19.3)

Figure S327.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #1: 'Time to Death'

'del_17q24.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0105 (Fisher's exact test), Q value = 0.057

Table S328.  Gene #65: 'del_17q24.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 38(17Q24.3) MUTATED 15 0 5 15 0 0 4 5 11 15 12 9 1
DEL PEAK 38(17Q24.3) WILD-TYPE 89 1 31 156 10 3 22 16 68 39 49 18 1

Figure S328.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_17q24.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0958 (Fisher's exact test), Q value = 0.24

Table S329.  Gene #65: 'del_17q24.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

nPatients T1 T2 T3 T4
ALL 20 107 413 66
DEL PEAK 38(17Q24.3) MUTATED 0 19 62 14
DEL PEAK 38(17Q24.3) WILD-TYPE 20 88 351 52

Figure S329.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #5: 'PATHOLOGY_T_STAGE'

'del_17q24.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.00165 (Fisher's exact test), Q value = 0.014

Table S330.  Gene #65: 'del_17q24.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 38(17Q24.3) MUTATED 38 30 27
DEL PEAK 38(17Q24.3) WILD-TYPE 304 119 87

Figure S330.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_17q24.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.0124 (Fisher's exact test), Q value = 0.062

Table S331.  Gene #65: 'del_17q24.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 38(17Q24.3) MUTATED 59 21
DEL PEAK 38(17Q24.3) WILD-TYPE 389 65

Figure S331.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_17q24.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 9.04e-05 (Wilcoxon-test), Q value = 0.0014

Table S332.  Gene #65: 'del_17q24.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 38(17Q24.3) MUTATED 90 3.1 (4.5)
DEL PEAK 38(17Q24.3) WILD-TYPE 483 2.1 (4.7)

Figure S332.  Get High-res Image Gene #65: 'del_17q24.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_18p11.31' versus 'YEARS_TO_BIRTH'

P value = 0.0134 (Wilcoxon-test), Q value = 0.065

Table S333.  Gene #66: 'del_18p11.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 39(18P11.31) MUTATED 365 65.4 (12.0)
DEL PEAK 39(18P11.31) WILD-TYPE 241 67.5 (13.7)

Figure S333.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_18p11.31' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 2.47e-06 (Fisher's exact test), Q value = 0.00026

Table S334.  Gene #66: 'del_18p11.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 39(18P11.31) MUTATED 240 122
DEL PEAK 39(18P11.31) WILD-TYPE 202 40

Figure S334.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_18p11.31' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00017 (Fisher's exact test), Q value = 0.0023

Table S335.  Gene #66: 'del_18p11.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 39(18P11.31) MUTATED 57 0 14 96 4 3 12 13 52 34 47 24 1
DEL PEAK 39(18P11.31) WILD-TYPE 47 1 22 75 6 0 14 8 27 20 14 3 1

Figure S335.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_18p11.31' versus 'PATHOLOGY_N_STAGE'

P value = 0.00669 (Fisher's exact test), Q value = 0.041

Table S336.  Gene #66: 'del_18p11.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 39(18P11.31) MUTATED 187 103 73
DEL PEAK 39(18P11.31) WILD-TYPE 155 46 41

Figure S336.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_18p11.31' versus 'PATHOLOGY_M_STAGE'

P value = 3.51e-06 (Fisher's exact test), Q value = 0.00026

Table S337.  Gene #66: 'del_18p11.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 39(18P11.31) MUTATED 254 71
DEL PEAK 39(18P11.31) WILD-TYPE 194 15

Figure S337.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_18p11.31' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S338.  Gene #66: 'del_18p11.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 39(18P11.31) MUTATED 229 10 116 6
DEL PEAK 39(18P11.31) WILD-TYPE 152 50 30 7

Figure S338.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_18p11.31' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0202 (Fisher's exact test), Q value = 0.087

Table S339.  Gene #66: 'del_18p11.31' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 39(18P11.31) MUTATED 260 2 29 14
DEL PEAK 39(18P11.31) WILD-TYPE 179 3 7 15

Figure S339.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_18p11.31' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0116 (Wilcoxon-test), Q value = 0.06

Table S340.  Gene #66: 'del_18p11.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 39(18P11.31) MUTATED 342 2.3 (4.3)
DEL PEAK 39(18P11.31) WILD-TYPE 231 2.1 (5.3)

Figure S340.  Get High-res Image Gene #66: 'del_18p11.31' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_18q12.2' versus 'YEARS_TO_BIRTH'

P value = 0.0225 (Wilcoxon-test), Q value = 0.094

Table S341.  Gene #67: 'del_18q12.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 40(18Q12.2) MUTATED 410 65.6 (12.1)
DEL PEAK 40(18Q12.2) WILD-TYPE 196 67.7 (13.9)

Figure S341.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_18q12.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 1.39e-09 (Fisher's exact test), Q value = 1.3e-06

Table S342.  Gene #67: 'del_18q12.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 40(18Q12.2) MUTATED 268 139
DEL PEAK 40(18Q12.2) WILD-TYPE 174 23

Figure S342.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_18q12.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00023 (Fisher's exact test), Q value = 0.0029

Table S343.  Gene #67: 'del_18q12.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 40(18Q12.2) MUTATED 60 0 21 105 4 3 15 17 59 40 52 23 1
DEL PEAK 40(18Q12.2) WILD-TYPE 44 1 15 66 6 0 11 4 20 14 9 4 1

Figure S343.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_18q12.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.00013 (Fisher's exact test), Q value = 0.0019

Table S344.  Gene #67: 'del_18q12.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 40(18Q12.2) MUTATED 205 115 87
DEL PEAK 40(18Q12.2) WILD-TYPE 137 34 27

Figure S344.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_18q12.2' versus 'PATHOLOGY_M_STAGE'

P value = 0.000216 (Fisher's exact test), Q value = 0.0027

Table S345.  Gene #67: 'del_18q12.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 40(18Q12.2) MUTATED 292 73
DEL PEAK 40(18Q12.2) WILD-TYPE 156 13

Figure S345.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_18q12.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S346.  Gene #67: 'del_18q12.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 40(18Q12.2) MUTATED 252 15 128 10
DEL PEAK 40(18Q12.2) WILD-TYPE 129 45 18 3

Figure S346.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_18q12.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0348 (Fisher's exact test), Q value = 0.12

Table S347.  Gene #67: 'del_18q12.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 40(18Q12.2) MUTATED 9 401
DEL PEAK 40(18Q12.2) WILD-TYPE 0 198

Figure S347.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_18q12.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0446 (Fisher's exact test), Q value = 0.15

Table S348.  Gene #67: 'del_18q12.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 40(18Q12.2) MUTATED 293 3 29 14
DEL PEAK 40(18Q12.2) WILD-TYPE 146 2 7 15

Figure S348.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_18q12.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000286 (Wilcoxon-test), Q value = 0.0035

Table S349.  Gene #67: 'del_18q12.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 40(18Q12.2) MUTATED 387 2.5 (5.0)
DEL PEAK 40(18Q12.2) WILD-TYPE 186 1.6 (3.9)

Figure S349.  Get High-res Image Gene #67: 'del_18q12.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_18q21.2' versus 'YEARS_TO_BIRTH'

P value = 0.0336 (Wilcoxon-test), Q value = 0.12

Table S350.  Gene #68: 'del_18q21.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 41(18Q21.2) MUTATED 427 65.7 (12.1)
DEL PEAK 41(18Q21.2) WILD-TYPE 179 67.7 (14.0)

Figure S350.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_18q21.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 3.47e-09 (Fisher's exact test), Q value = 1.6e-06

Table S351.  Gene #68: 'del_18q21.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 41(18Q21.2) MUTATED 282 142
DEL PEAK 41(18Q21.2) WILD-TYPE 160 20

Figure S351.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_18q21.2' versus 'NEOPLASM_DISEASESTAGE'

P value = 3e-05 (Fisher's exact test), Q value = 0.00069

Table S352.  Gene #68: 'del_18q21.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 41(18Q21.2) MUTATED 62 0 23 107 4 3 16 17 62 43 55 24 2
DEL PEAK 41(18Q21.2) WILD-TYPE 42 1 13 64 6 0 10 4 17 11 6 3 0

Figure S352.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_18q21.2' versus 'PATHOLOGY_N_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S353.  Gene #68: 'del_18q21.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 41(18Q21.2) MUTATED 211 119 94
DEL PEAK 41(18Q21.2) WILD-TYPE 131 30 20

Figure S353.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_18q21.2' versus 'PATHOLOGY_M_STAGE'

P value = 3.68e-06 (Fisher's exact test), Q value = 0.00026

Table S354.  Gene #68: 'del_18q21.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 41(18Q21.2) MUTATED 302 78
DEL PEAK 41(18Q21.2) WILD-TYPE 146 8

Figure S354.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_18q21.2' versus 'GENDER'

P value = 0.0913 (Fisher's exact test), Q value = 0.23

Table S355.  Gene #68: 'del_18q21.2' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
DEL PEAK 41(18Q21.2) MUTATED 191 236
DEL PEAK 41(18Q21.2) WILD-TYPE 95 86

Figure S355.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #8: 'GENDER'

'del_18q21.2' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S356.  Gene #68: 'del_18q21.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 41(18Q21.2) MUTATED 264 17 129 11
DEL PEAK 41(18Q21.2) WILD-TYPE 117 43 17 2

Figure S356.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_18q21.2' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.064 (Fisher's exact test), Q value = 0.19

Table S357.  Gene #68: 'del_18q21.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 41(18Q21.2) MUTATED 9 418
DEL PEAK 41(18Q21.2) WILD-TYPE 0 181

Figure S357.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_18q21.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0413 (Fisher's exact test), Q value = 0.14

Table S358.  Gene #68: 'del_18q21.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 41(18Q21.2) MUTATED 303 3 30 15
DEL PEAK 41(18Q21.2) WILD-TYPE 136 2 6 14

Figure S358.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_18q21.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 2.75e-06 (Wilcoxon-test), Q value = 0.00026

Table S359.  Gene #68: 'del_18q21.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 41(18Q21.2) MUTATED 403 2.6 (5.0)
DEL PEAK 41(18Q21.2) WILD-TYPE 170 1.4 (3.9)

Figure S359.  Get High-res Image Gene #68: 'del_18q21.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_18q22.1' versus 'YEARS_TO_BIRTH'

P value = 0.0915 (Wilcoxon-test), Q value = 0.23

Table S360.  Gene #69: 'del_18q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 606 66.3 (12.7)
DEL PEAK 42(18Q22.1) MUTATED 422 65.8 (12.1)
DEL PEAK 42(18Q22.1) WILD-TYPE 184 67.4 (14.0)

Figure S360.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_18q22.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 1.63e-07 (Fisher's exact test), Q value = 3.9e-05

Table S361.  Gene #69: 'del_18q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 42(18Q22.1) MUTATED 281 138
DEL PEAK 42(18Q22.1) WILD-TYPE 161 24

Figure S361.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_18q22.1' versus 'NEOPLASM_DISEASESTAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S362.  Gene #69: 'del_18q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 42(18Q22.1) MUTATED 62 0 23 107 4 3 14 16 61 43 54 24 2
DEL PEAK 42(18Q22.1) WILD-TYPE 42 1 13 64 6 0 12 5 18 11 7 3 0

Figure S362.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_18q22.1' versus 'PATHOLOGY_N_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S363.  Gene #69: 'del_18q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 42(18Q22.1) MUTATED 211 115 93
DEL PEAK 42(18Q22.1) WILD-TYPE 131 34 21

Figure S363.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_18q22.1' versus 'PATHOLOGY_M_STAGE'

P value = 8.34e-06 (Fisher's exact test), Q value = 0.00026

Table S364.  Gene #69: 'del_18q22.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 42(18Q22.1) MUTATED 299 77
DEL PEAK 42(18Q22.1) WILD-TYPE 149 9

Figure S364.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_18q22.1' versus 'GENDER'

P value = 0.095 (Fisher's exact test), Q value = 0.24

Table S365.  Gene #69: 'del_18q22.1' versus Clinical Feature #8: 'GENDER'

nPatients FEMALE MALE
ALL 286 322
DEL PEAK 42(18Q22.1) MUTATED 189 233
DEL PEAK 42(18Q22.1) WILD-TYPE 97 89

Figure S365.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #8: 'GENDER'

'del_18q22.1' versus 'HISTOLOGICAL_TYPE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00026

Table S366.  Gene #69: 'del_18q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 42(18Q22.1) MUTATED 264 16 127 10
DEL PEAK 42(18Q22.1) WILD-TYPE 117 44 19 3

Figure S366.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_18q22.1' versus 'RADIATIONS_RADIATION_REGIMENINDICATION'

P value = 0.0633 (Fisher's exact test), Q value = 0.19

Table S367.  Gene #69: 'del_18q22.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

nPatients NO YES
ALL 9 599
DEL PEAK 42(18Q22.1) MUTATED 9 413
DEL PEAK 42(18Q22.1) WILD-TYPE 0 186

Figure S367.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #10: 'RADIATIONS_RADIATION_REGIMENINDICATION'

'del_18q22.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0826 (Fisher's exact test), Q value = 0.22

Table S368.  Gene #69: 'del_18q22.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 439 5 36 29
DEL PEAK 42(18Q22.1) MUTATED 300 3 29 15
DEL PEAK 42(18Q22.1) WILD-TYPE 139 2 7 14

Figure S368.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #11: 'COMPLETENESS_OF_RESECTION'

'del_18q22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 2.47e-05 (Wilcoxon-test), Q value = 6e-04

Table S369.  Gene #69: 'del_18q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 42(18Q22.1) MUTATED 400 2.6 (5.0)
DEL PEAK 42(18Q22.1) WILD-TYPE 173 1.5 (3.9)

Figure S369.  Get High-res Image Gene #69: 'del_18q22.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_19p13.3' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.0767 (Fisher's exact test), Q value = 0.21

Table S370.  Gene #70: 'del_19p13.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 43(19P13.3) MUTATED 62 33
DEL PEAK 43(19P13.3) WILD-TYPE 380 129

Figure S370.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_19p13.3' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.00779 (Fisher's exact test), Q value = 0.046

Table S371.  Gene #70: 'del_19p13.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 43(19P13.3) MUTATED 11 0 4 19 0 1 5 5 10 15 15 8 1
DEL PEAK 43(19P13.3) WILD-TYPE 93 1 32 152 10 2 21 16 69 39 46 19 1

Figure S371.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_19p13.3' versus 'PATHOLOGY_N_STAGE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00083

Table S372.  Gene #70: 'del_19p13.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 43(19P13.3) MUTATED 36 28 32
DEL PEAK 43(19P13.3) WILD-TYPE 306 121 82

Figure S372.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_19p13.3' versus 'PATHOLOGY_M_STAGE'

P value = 0.00594 (Fisher's exact test), Q value = 0.037

Table S373.  Gene #70: 'del_19p13.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 43(19P13.3) MUTATED 63 23
DEL PEAK 43(19P13.3) WILD-TYPE 385 63

Figure S373.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_19p13.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.0871 (Fisher's exact test), Q value = 0.23

Table S374.  Gene #70: 'del_19p13.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 43(19P13.3) MUTATED 56 5 31 1
DEL PEAK 43(19P13.3) WILD-TYPE 325 55 115 12

Figure S374.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_19p13.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 4.91e-06 (Wilcoxon-test), Q value = 0.00026

Table S375.  Gene #70: 'del_19p13.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 43(19P13.3) MUTATED 90 3.9 (6.0)
DEL PEAK 43(19P13.3) WILD-TYPE 483 1.9 (4.4)

Figure S375.  Get High-res Image Gene #70: 'del_19p13.3' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_20p12.1' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.00528 (Fisher's exact test), Q value = 0.034

Table S376.  Gene #71: 'del_20p12.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 44(20P12.1) MUTATED 83 48
DEL PEAK 44(20P12.1) WILD-TYPE 359 114

Figure S376.  Get High-res Image Gene #71: 'del_20p12.1' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_20p12.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.00401 (Fisher's exact test), Q value = 0.027

Table S377.  Gene #71: 'del_20p12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 44(20P12.1) MUTATED 77 6 43 5
DEL PEAK 44(20P12.1) WILD-TYPE 304 54 103 8

Figure S377.  Get High-res Image Gene #71: 'del_20p12.1' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_20p12.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0613 (Wilcoxon-test), Q value = 0.18

Table S378.  Gene #71: 'del_20p12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 44(20P12.1) MUTATED 127 2.7 (5.2)
DEL PEAK 44(20P12.1) WILD-TYPE 446 2.1 (4.6)

Figure S378.  Get High-res Image Gene #71: 'del_20p12.1' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_21q11.2' versus 'PRIMARY_SITE_OF_DISEASE'

P value = 0.00362 (Fisher's exact test), Q value = 0.025

Table S379.  Gene #72: 'del_21q11.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

nPatients COLON RECTUM
ALL 442 162
DEL PEAK 45(21Q11.2) MUTATED 136 71
DEL PEAK 45(21Q11.2) WILD-TYPE 306 91

Figure S379.  Get High-res Image Gene #72: 'del_21q11.2' versus Clinical Feature #3: 'PRIMARY_SITE_OF_DISEASE'

'del_21q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0681 (Fisher's exact test), Q value = 0.2

Table S380.  Gene #72: 'del_21q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 45(21Q11.2) MUTATED 106 56 48
DEL PEAK 45(21Q11.2) WILD-TYPE 236 93 66

Figure S380.  Get High-res Image Gene #72: 'del_21q11.2' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_21q11.2' versus 'HISTOLOGICAL_TYPE'

P value = 7e-05 (Fisher's exact test), Q value = 0.0012

Table S381.  Gene #72: 'del_21q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 45(21Q11.2) MUTATED 127 8 66 3
DEL PEAK 45(21Q11.2) WILD-TYPE 254 52 80 10

Figure S381.  Get High-res Image Gene #72: 'del_21q11.2' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_21q11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0174 (Wilcoxon-test), Q value = 0.079

Table S382.  Gene #72: 'del_21q11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 45(21Q11.2) MUTATED 199 3.0 (6.2)
DEL PEAK 45(21Q11.2) WILD-TYPE 374 1.8 (3.6)

Figure S382.  Get High-res Image Gene #72: 'del_21q11.2' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

'del_22q13.32' versus 'Time to Death'

P value = 0.0354 (logrank test), Q value = 0.12

Table S383.  Gene #73: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 583 115 0.0 - 140.4 (19.1)
DEL PEAK 46(22Q13.32) MUTATED 212 48 0.2 - 140.4 (17.4)
DEL PEAK 46(22Q13.32) WILD-TYPE 371 67 0.0 - 139.2 (19.7)

Figure S383.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'

'del_22q13.32' versus 'NEOPLASM_DISEASESTAGE'

P value = 0.0129 (Fisher's exact test), Q value = 0.063

Table S384.  Gene #73: 'del_22q13.32' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

nPatients STAGE I STAGE IA STAGE II STAGE IIA STAGE IIB STAGE IIC STAGE III STAGE IIIA STAGE IIIB STAGE IIIC STAGE IV STAGE IVA STAGE IVB
ALL 104 1 36 171 10 3 26 21 79 54 61 27 2
DEL PEAK 46(22Q13.32) MUTATED 29 0 9 58 1 1 10 12 31 24 33 11 0
DEL PEAK 46(22Q13.32) WILD-TYPE 75 1 27 113 9 2 16 9 48 30 28 16 2

Figure S384.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #4: 'NEOPLASM_DISEASESTAGE'

'del_22q13.32' versus 'PATHOLOGY_N_STAGE'

P value = 2e-04 (Fisher's exact test), Q value = 0.0027

Table S385.  Gene #73: 'del_22q13.32' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

nPatients N0 N1 N2
ALL 342 149 114
DEL PEAK 46(22Q13.32) MUTATED 102 71 51
DEL PEAK 46(22Q13.32) WILD-TYPE 240 78 63

Figure S385.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #6: 'PATHOLOGY_N_STAGE'

'del_22q13.32' versus 'PATHOLOGY_M_STAGE'

P value = 0.00699 (Fisher's exact test), Q value = 0.042

Table S386.  Gene #73: 'del_22q13.32' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

nPatients 0 1
ALL 448 86
DEL PEAK 46(22Q13.32) MUTATED 153 43
DEL PEAK 46(22Q13.32) WILD-TYPE 295 43

Figure S386.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #7: 'PATHOLOGY_M_STAGE'

'del_22q13.32' versus 'HISTOLOGICAL_TYPE'

P value = 0.00741 (Fisher's exact test), Q value = 0.044

Table S387.  Gene #73: 'del_22q13.32' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

nPatients COLON ADENOCARCINOMA COLON MUCINOUS ADENOCARCINOMA RECTAL ADENOCARCINOMA RECTAL MUCINOUS ADENOCARCINOMA
ALL 381 60 146 13
DEL PEAK 46(22Q13.32) MUTATED 145 11 62 4
DEL PEAK 46(22Q13.32) WILD-TYPE 236 49 84 9

Figure S387.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #9: 'HISTOLOGICAL_TYPE'

'del_22q13.32' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00021 (Wilcoxon-test), Q value = 0.0027

Table S388.  Gene #73: 'del_22q13.32' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 573 2.2 (4.7)
DEL PEAK 46(22Q13.32) MUTATED 212 2.9 (5.2)
DEL PEAK 46(22Q13.32) WILD-TYPE 361 1.8 (4.4)

Figure S388.  Get High-res Image Gene #73: 'del_22q13.32' versus Clinical Feature #12: 'NUMBER_OF_LYMPH_NODES'

Methods & Data
Input

  • Copy number data file = all_lesions.txt from GISTIC pipeline

  • Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/COADREAD-TP/15089877/transformed.cor.cli.txt

  • Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/COADREAD-TP/15076882/COADREAD-TP.merged_data.txt

  • Number of patients = 608

  • Number of significantly focal cnvs = 73

  • Number of selected clinical features = 13

  • Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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