Correlation between gene mutation status and molecular subtypes

Lymphoid Neoplasm Diffuse Large B-cell Lymphoma (Primary solid tumor)

21 August 2015 | analyses__2015_08_21

Maintainer Information

Citation Information

Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)

Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Correlation between gene mutation status and molecular subtypes. Broad Institute of MIT and Harvard. doi:10.7908/C1Q81C8V

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 94 genes and 10 molecular subtypes across 41 patients, no significant finding detected with P value < 0.05 and Q value < 0.25.

No gene mutations related to molecuar subtypes.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 94 genes and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, no significant finding detected.


		Clinical Features	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
MYD88	3 (7%)	38	0.243 (1.00)	0.232 (1.00)	1 (1.00)	0.766 (1.00)	0.429 (1.00)		0.382 (1.00)	0.646 (1.00)	0.593 (1.00)	0.363 (1.00)
FRG1	9 (22%)	32	0.706 (1.00)	0.719 (1.00)	0.39 (1.00)	0.849 (1.00)	1 (1.00)	0.359 (1.00)	0.27 (1.00)	0.0617 (1.00)	1 (1.00)	0.0367 (1.00)
MLL2	14 (34%)	27	0.0969 (1.00)	0.326 (1.00)	1 (1.00)	1 (1.00)	0.642 (1.00)	0.1 (1.00)	0.337 (1.00)	0.199 (1.00)	0.502 (1.00)	0.203 (1.00)
TPPP	5 (12%)	36	1 (1.00)	0.184 (1.00)	0.598 (1.00)	0.765 (1.00)	0.603 (1.00)	0.301 (1.00)	0.689 (1.00)	0.727 (1.00)	1 (1.00)	0.651 (1.00)
CHIT1	6 (15%)	35	1 (1.00)	1 (1.00)	0.651 (1.00)	0.447 (1.00)	0.486 (1.00)		0.432 (1.00)	0.827 (1.00)	0.167 (1.00)	0.929 (1.00)
B2M	8 (20%)	33	0.0594 (1.00)	0.697 (1.00)	0.39 (1.00)	0.85 (1.00)	1 (1.00)	0.393 (1.00)	0.12 (1.00)	0.906 (1.00)	0.408 (1.00)	0.398 (1.00)
TPTE2	11 (27%)	30	1 (1.00)	1 (1.00)	0.169 (1.00)	0.448 (1.00)	0.659 (1.00)	0.47 (1.00)	0.179 (1.00)	0.652 (1.00)	0.695 (1.00)	0.351 (1.00)
RHPN2	6 (15%)	35	0.679 (1.00)	1 (1.00)	0.0996 (1.00)	0.0766 (1.00)	1 (1.00)	0.289 (1.00)	0.533 (1.00)	0.181 (1.00)	0.662 (1.00)	0.0105 (1.00)
FOXD4L1	7 (17%)	34	0.438 (1.00)	0.697 (1.00)	1 (1.00)	0.266 (1.00)	1 (1.00)	0.233 (1.00)	0.946 (1.00)	0.966 (1.00)	0.182 (1.00)	0.498 (1.00)
DND1	5 (12%)	36	0.638 (1.00)	1 (1.00)	1 (1.00)	0.375 (1.00)	1 (1.00)	0.232 (1.00)	0.519 (1.00)	0.959 (1.00)	0.605 (1.00)	0.232 (1.00)
ATXN1	7 (17%)	34	1 (1.00)	0.697 (1.00)	0.598 (1.00)	0.487 (1.00)	1 (1.00)	1 (1.00)	0.248 (1.00)	0.234 (1.00)	0.408 (1.00)	0.534 (1.00)
TP53	6 (15%)	35	0.0704 (1.00)	0.663 (1.00)	1 (1.00)	0.765 (1.00)	0.171 (1.00)		0.216 (1.00)	0.329 (1.00)	1 (1.00)	0.943 (1.00)
CDC27	10 (24%)	31	1 (1.00)	0.484 (1.00)	1 (1.00)	0.623 (1.00)	1 (1.00)	0.856 (1.00)	0.39 (1.00)	0.044 (1.00)	0.0652 (1.00)	0.265 (1.00)
EPB41L4A	4 (10%)	37	0.618 (1.00)	0.343 (1.00)	0.598 (1.00)	0.765 (1.00)	0.486 (1.00)		0.611 (1.00)	0.612 (1.00)	0.605 (1.00)	0.983 (1.00)
NOTCH2NL	4 (10%)	37	1 (1.00)	0.343 (1.00)	0.483 (1.00)		1 (1.00)		0.891 (1.00)	0.896 (1.00)	0.605 (1.00)	0.113 (1.00)
KRT3	4 (10%)	37	1 (1.00)	1 (1.00)	0.224 (1.00)		0.486 (1.00)		0.891 (1.00)	0.895 (1.00)	1 (1.00)	0.325 (1.00)
OR1S2	10 (24%)	31	0.467 (1.00)	1 (1.00)	0.651 (1.00)	0.599 (1.00)	0.611 (1.00)	0.671 (1.00)	0.643 (1.00)	0.695 (1.00)	0.434 (1.00)	0.74 (1.00)
RGPD5	5 (12%)	36	0.0563 (1.00)	0.184 (1.00)	1 (1.00)	0.266 (1.00)	1 (1.00)		0.853 (1.00)	0.611 (1.00)	1 (1.00)	0.141 (1.00)
TNFAIP3	6 (15%)	35	0.0266 (1.00)	1 (1.00)	0.651 (1.00)	0.819 (1.00)	0.486 (1.00)		0.327 (1.00)	0.523 (1.00)	0.342 (1.00)	0.0232 (1.00)
RBMXL1	4 (10%)	37	1 (1.00)	0.343 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)		0.893 (1.00)	0.407 (1.00)	1 (1.00)	0.56 (1.00)
CCDC66	4 (10%)	37	1 (1.00)	0.0478 (1.00)	0.224 (1.00)		0.104 (1.00)	0.0553 (1.00)	0.102 (1.00)	0.111 (1.00)	0.231 (1.00)	0.21 (1.00)
NOTCH2	7 (17%)	34	0.438 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.338 (1.00)	0.183 (1.00)	0.808 (1.00)	0.84 (1.00)	0.662 (1.00)	0.276 (1.00)
PCMTD1	6 (15%)	35	1 (1.00)	1 (1.00)	0.651 (1.00)	0.551 (1.00)	1 (1.00)	0.288 (1.00)	0.43 (1.00)	0.329 (1.00)	0.662 (1.00)	0.575 (1.00)
FAM120B	5 (12%)	36	1 (1.00)	1 (1.00)	0.224 (1.00)	0.264 (1.00)	1 (1.00)	1 (1.00)	0.411 (1.00)	0.0848 (1.00)	0.326 (1.00)	0.772 (1.00)
SMARCA2	4 (10%)	37	1 (1.00)	0.343 (1.00)	0.224 (1.00)		0.603 (1.00)	0.504 (1.00)	0.225 (1.00)	0.328 (1.00)	0.106 (1.00)	0.828 (1.00)
C11ORF40	4 (10%)	37	1 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)		0.773 (1.00)	0.946 (1.00)	0.593 (1.00)	0.121 (1.00)
ZSCAN5A	3 (7%)	38	0.573 (1.00)	0.107 (1.00)			0.486 (1.00)		0.381 (1.00)	0.77 (1.00)	0.231 (1.00)	0.512 (1.00)
KRTAP4-5	4 (10%)	37	1 (1.00)	0.343 (1.00)	1 (1.00)		1 (1.00)	0.231 (1.00)	0.425 (1.00)	0.474 (1.00)	0.605 (1.00)	0.0479 (1.00)
DEFA1	4 (10%)	37	1 (1.00)	1 (1.00)	1 (1.00)		0.229 (1.00)	0.15 (1.00)	0.382 (1.00)	0.254 (1.00)	0.106 (1.00)	0.327 (1.00)
SIRPA	5 (12%)	36	1 (1.00)	0.663 (1.00)	0.598 (1.00)	0.766 (1.00)	0.338 (1.00)	0.455 (1.00)	0.523 (1.00)	0.121 (1.00)	0.342 (1.00)	0.083 (1.00)
TMPRSS13	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	1 (1.00)		1 (1.00)	0.764 (1.00)	0.159 (1.00)	0.0114 (1.00)	1 (1.00)	0.511 (1.00)
CYP2A6	4 (10%)	37	0.303 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)	0.762 (1.00)	0.0173 (1.00)	0.0784 (1.00)	0.605 (1.00)	0.191 (1.00)
AR	7 (17%)	34	1 (1.00)	0.697 (1.00)	0.0996 (1.00)	0.0781 (1.00)	0.338 (1.00)	0.816 (1.00)	0.32 (1.00)	0.841 (1.00)	0.662 (1.00)	0.0437 (1.00)
ARHGEF5	3 (7%)	38	1 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)	0.432 (1.00)	0.887 (1.00)	0.772 (1.00)	0.487 (1.00)
RNF39	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	0.483 (1.00)		1 (1.00)	0.764 (1.00)	0.887 (1.00)	0.435 (1.00)	1 (1.00)	0.212 (1.00)
ABCA1	5 (12%)	36	0.638 (1.00)	0.663 (1.00)	1 (1.00)		1 (1.00)	0.23 (1.00)	1 (1.00)	0.884 (1.00)	1 (1.00)	0.423 (1.00)
CS	3 (7%)	38	1 (1.00)	0.107 (1.00)	0.483 (1.00)		1 (1.00)		0.381 (1.00)	0.333 (1.00)	0.231 (1.00)	0.0877 (1.00)
IFITM3	4 (10%)	37	0.618 (1.00)	1 (1.00)	0.224 (1.00)	0.268 (1.00)	0.603 (1.00)	0.631 (1.00)	0.429 (1.00)	0.0717 (1.00)	0.605 (1.00)	0.0146 (1.00)
RANBP2	6 (15%)	35	1 (1.00)	1 (1.00)	0.651 (1.00)	1 (1.00)	0.229 (1.00)	0.149 (1.00)	0.831 (1.00)	0.428 (1.00)	0.662 (1.00)	0.574 (1.00)
KLHL6	6 (15%)	35	0.377 (1.00)	1 (1.00)	0.33 (1.00)	0.359 (1.00)	0.338 (1.00)	0.812 (1.00)	0.831 (1.00)	0.351 (1.00)	0.342 (1.00)	0.565 (1.00)
ZNF814	10 (24%)	31	0.142 (1.00)	0.484 (1.00)	0.651 (1.00)	0.513 (1.00)	0.229 (1.00)	0.761 (1.00)	0.0506 (1.00)	0.0193 (1.00)	0.695 (1.00)	0.0122 (1.00)
CYP4A11	4 (10%)	37	0.618 (1.00)	1 (1.00)	0.224 (1.00)	0.267 (1.00)	1 (1.00)	1 (1.00)	0.773 (1.00)	0.203 (1.00)	0.326 (1.00)	0.191 (1.00)
PIM1	8 (20%)	33	1 (1.00)	0.00345 (1.00)	0.651 (1.00)	1 (1.00)	0.171 (1.00)		0.0995 (1.00)	0.0745 (1.00)	0.0365 (1.00)	0.474 (1.00)
POTEE	7 (17%)	34	1 (1.00)	1 (1.00)	0.0421 (1.00)	0.12 (1.00)	1 (1.00)	0.123 (1.00)	0.0631 (1.00)	0.00183 (1.00)	1 (1.00)	0.0375 (1.00)
OR52E6	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	1 (1.00)		1 (1.00)	0.429 (1.00)	0.885 (1.00)	0.435 (1.00)	1 (1.00)	0.212 (1.00)
NBPF10	9 (22%)	32	0.471 (1.00)	0.13 (1.00)	0.651 (1.00)	0.344 (1.00)	1 (1.00)	0.232 (1.00)	0.388 (1.00)	0.212 (1.00)	0.434 (1.00)	0.986 (1.00)
PRB2	9 (22%)	32	0.471 (1.00)	1 (1.00)	0.39 (1.00)	0.701 (1.00)	0.104 (1.00)	0.0541 (1.00)	0.163 (1.00)	0.0234 (1.00)	0.408 (1.00)	0.475 (1.00)
MUC6	21 (51%)	20	0.536 (1.00)	0.758 (1.00)	1 (1.00)	0.173 (1.00)	0.396 (1.00)	0.157 (1.00)	0.787 (1.00)	0.887 (1.00)	0.316 (1.00)	0.934 (1.00)
SALL1	5 (12%)	36	1 (1.00)	0.663 (1.00)	0.598 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)	0.218 (1.00)	1 (1.00)	0.325 (1.00)
PAK2	7 (17%)	34	0.112 (1.00)	1 (1.00)	0.598 (1.00)	1 (1.00)	1 (1.00)	0.671 (1.00)	0.324 (1.00)	0.442 (1.00)	0.182 (1.00)	0.0866 (1.00)
FLG	17 (41%)	24	0.76 (1.00)	1 (1.00)	0.71 (1.00)	1 (1.00)	1 (1.00)	0.0494 (1.00)	1 (1.00)	0.563 (1.00)	1 (1.00)	0.0186 (1.00)
MUC17	13 (32%)	28	0.179 (1.00)	0.181 (1.00)	0.682 (1.00)	0.352 (1.00)	1 (1.00)	0.855 (1.00)	0.616 (1.00)	0.571 (1.00)	0.483 (1.00)	0.39 (1.00)
OR2T4	8 (20%)	33	0.0594 (1.00)	0.13 (1.00)	0.651 (1.00)	0.217 (1.00)	0.104 (1.00)	0.301 (1.00)	0.0102 (1.00)	0.179 (1.00)	0.236 (1.00)	0.00789 (1.00)
AMAC1L3	5 (12%)	36	1 (1.00)	0.663 (1.00)	0.0996 (1.00)	0.264 (1.00)	0.611 (1.00)	0.286 (1.00)	0.314 (1.00)	0.0189 (1.00)	0.65 (1.00)	0.0654 (1.00)
APOB	3 (7%)	38	1 (1.00)	0.107 (1.00)	1 (1.00)		0.486 (1.00)		0.157 (1.00)	0.773 (1.00)	0.231 (1.00)	0.212 (1.00)
KRTAP4-7	8 (20%)	33	0.0594 (1.00)	1 (1.00)	0.682 (1.00)	0.382 (1.00)	0.0451 (1.00)	0.453 (1.00)	0.77 (1.00)	0.233 (1.00)	0.236 (1.00)	0.271 (1.00)
MUC16	13 (32%)	28	0.321 (1.00)	0.181 (1.00)	0.427 (1.00)	0.182 (1.00)	0.673 (1.00)	1 (1.00)	0.883 (1.00)	0.682 (1.00)	0.481 (1.00)	0.468 (1.00)
NEFH	6 (15%)	35	0.205 (1.00)	0.663 (1.00)	0.0421 (1.00)	0.091 (1.00)	1 (1.00)	0.296 (1.00)	0.939 (1.00)	0.613 (1.00)	0.391 (1.00)	0.0921 (1.00)
KCNN3	7 (17%)	34	0.209 (1.00)	1 (1.00)	0.215 (1.00)	0.621 (1.00)	1 (1.00)	0.814 (1.00)	0.946 (1.00)	0.366 (1.00)	1 (1.00)	0.39 (1.00)
RNASEH2B	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	1 (1.00)				0.0185 (1.00)	0.473 (1.00)	0.593 (1.00)	0.274 (1.00)
FAM153B	3 (7%)	38	1 (1.00)	1 (1.00)	1 (1.00)	0.374 (1.00)	1 (1.00)		1 (1.00)	1 (1.00)	0.593 (1.00)	0.735 (1.00)
OTOP1	4 (10%)	37	0.303 (1.00)	1 (1.00)	0.598 (1.00)	0.765 (1.00)	1 (1.00)	0.764 (1.00)	0.304 (1.00)	0.475 (1.00)	1 (1.00)	0.713 (1.00)
AATK	3 (7%)	38	0.573 (1.00)	1 (1.00)	0.483 (1.00)		1 (1.00)	0.431 (1.00)	0.888 (1.00)	0.436 (1.00)	1 (1.00)	0.0876 (1.00)
ARID1A	5 (12%)	36	1 (1.00)	0.663 (1.00)	1 (1.00)		1 (1.00)	0.231 (1.00)	0.525 (1.00)	0.727 (1.00)	0.106 (1.00)	0.0286 (1.00)
GUCA1C	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	1 (1.00)		1 (1.00)	0.43 (1.00)	0.888 (1.00)	0.438 (1.00)	1 (1.00)	0.21 (1.00)
TRIM48	8 (20%)	33	1 (1.00)	1 (1.00)	0.682 (1.00)	0.383 (1.00)	0.229 (1.00)	0.149 (1.00)	0.873 (1.00)	1 (1.00)	1 (1.00)	0.345 (1.00)
CSGALNACT2	5 (12%)	36	1 (1.00)	1 (1.00)	0.224 (1.00)	0.268 (1.00)	1 (1.00)	0.545 (1.00)	0.523 (1.00)	0.122 (1.00)	0.342 (1.00)	0.0835 (1.00)
CRIPAK	6 (15%)	35	0.679 (1.00)	0.00862 (1.00)	0.224 (1.00)		0.178 (1.00)	0.582 (1.00)	0.0272 (1.00)	0.0726 (1.00)	0.0203 (1.00)	0.257 (1.00)
DHRS4	4 (10%)	37	1 (1.00)	0.0478 (1.00)	0.224 (1.00)		0.104 (1.00)	0.0555 (1.00)	0.103 (1.00)	0.112 (1.00)	0.231 (1.00)	0.212 (1.00)
FAM21A	4 (10%)	37	0.618 (1.00)	0.343 (1.00)	0.483 (1.00)		0.229 (1.00)	0.432 (1.00)	0.613 (1.00)	0.611 (1.00)	0.106 (1.00)	0.421 (1.00)
KIAA1529	4 (10%)	37	0.618 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)	0.43 (1.00)	1 (1.00)	0.759 (1.00)	1 (1.00)	0.268 (1.00)
OR2M5	4 (10%)	37	0.618 (1.00)	0.606 (1.00)	0.224 (1.00)	0.0665 (1.00)	0.0632 (1.00)	0.295 (1.00)	0.102 (1.00)	0.228 (1.00)	0.0952 (1.00)	0.268 (1.00)
KRT6A	4 (10%)	37	0.303 (1.00)	0.606 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.432 (1.00)	1 (1.00)	0.894 (1.00)	0.593 (1.00)	1 (1.00)
CYP2F1	4 (10%)	37	1 (1.00)	0.343 (1.00)	0.224 (1.00)		0.229 (1.00)	0.149 (1.00)	0.227 (1.00)	0.0527 (1.00)	0.106 (1.00)	0.191 (1.00)
FCGBP	5 (12%)	36	0.638 (1.00)	0.184 (1.00)	1 (1.00)		0.603 (1.00)	0.23 (1.00)	1 (1.00)	0.816 (1.00)	1 (1.00)	0.598 (1.00)
ZNF493	4 (10%)	37	0.618 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)	0.432 (1.00)	1 (1.00)	0.683 (1.00)	1 (1.00)	0.27 (1.00)
HLA-B	7 (17%)	34	0.438 (1.00)	0.697 (1.00)	0.33 (1.00)	0.12 (1.00)	0.603 (1.00)	0.632 (1.00)	0.946 (1.00)	0.664 (1.00)	1 (1.00)	0.0396 (1.00)
FCRLA	3 (7%)	38	1 (1.00)	0.606 (1.00)			1 (1.00)	0.432 (1.00)	0.886 (1.00)	0.771 (1.00)	0.487 (1.00)
KLRC2	5 (12%)	36	1 (1.00)	0.663 (1.00)	0.598 (1.00)	0.763 (1.00)	0.338 (1.00)	0.815 (1.00)	0.524 (1.00)	0.247 (1.00)	0.106 (1.00)	0.829 (1.00)
CD79B	5 (12%)	36	0.638 (1.00)	0.343 (1.00)	0.0996 (1.00)	0.114 (1.00)	1 (1.00)		0.69 (1.00)	0.635 (1.00)	0.593 (1.00)	0.362 (1.00)
TMSB4X	5 (12%)	36	0.363 (1.00)	0.184 (1.00)	0.651 (1.00)	0.557 (1.00)	1 (1.00)	0.572 (1.00)	0.317 (1.00)	0.468 (1.00)	0.342 (1.00)	0.699 (1.00)
PRB1	5 (12%)	36	0.363 (1.00)	0.0207 (1.00)	1 (1.00)		0.229 (1.00)	0.152 (1.00)	0.0811 (1.00)	0.702 (1.00)	0.0473 (1.00)	0.345 (1.00)
PCDHA7	4 (10%)	37	0.303 (1.00)	0.606 (1.00)	0.598 (1.00)	1 (1.00)	0.0211 (1.00)	0.00691 (1.00)	0.103 (1.00)	0.0477 (1.00)	0.326 (1.00)	0.715 (1.00)
OR5H14	3 (7%)	38	0.573 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.429 (1.00)		0.382 (1.00)	0.646 (1.00)	0.593 (1.00)	0.651 (1.00)
PER3	4 (10%)	37	0.118 (1.00)	1 (1.00)	1 (1.00)		1 (1.00)		1 (1.00)	0.498 (1.00)	0.487 (1.00)
PABPC1	7 (17%)	34	0.679 (1.00)	1 (1.00)	1 (1.00)	0.82 (1.00)	0.338 (1.00)	0.45 (1.00)	0.671 (1.00)	0.362 (1.00)	0.684 (1.00)	0.0884 (1.00)
ITGA6	3 (7%)	38	1 (1.00)	0.606 (1.00)	1 (1.00)		0.486 (1.00)		0.784 (1.00)	0.77 (1.00)	1 (1.00)	0.269 (1.00)
IGSF3	6 (15%)	35	0.679 (1.00)	1 (1.00)	1 (1.00)	0.216 (1.00)	0.272 (1.00)	0.12 (1.00)	0.691 (1.00)	0.769 (1.00)	1 (1.00)	0.788 (1.00)
KRTAP1-1	3 (7%)	38	1 (1.00)	0.606 (1.00)	1 (1.00)		1 (1.00)	0.765 (1.00)	0.16 (1.00)	0.331 (1.00)	1 (1.00)	0.103 (1.00)
C15ORF39	3 (7%)	38	0.573 (1.00)	0.606 (1.00)	0.483 (1.00)		1 (1.00)	0.763 (1.00)	0.887 (1.00)	0.438 (1.00)	1 (1.00)	0.211 (1.00)
FBXO34	3 (7%)	38	0.573 (1.00)	1 (1.00)	0.483 (1.00)		1 (1.00)		0.6 (1.00)	0.19 (1.00)	0.593 (1.00)	0.0889 (1.00)
ZNF880	8 (20%)	33	1 (1.00)	0.13 (1.00)	1 (1.00)	0.819 (1.00)	0.659 (1.00)	1 (1.00)	0.474 (1.00)	0.236 (1.00)	0.0438 (1.00)	0.105 (1.00)
NBPF15	4 (10%)	37	1 (1.00)	1 (1.00)	1 (1.00)	1 (1.00)	0.603 (1.00)	0.79 (1.00)	0.772 (1.00)	0.331 (1.00)	0.605 (1.00)	0.826 (1.00)
SLC22A16	3 (7%)	38	1 (1.00)	0.606 (1.00)			1 (1.00)	0.432 (1.00)	0.887 (1.00)	0.77 (1.00)	0.487 (1.00)

'MYD88 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 1

Table S1. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
MYD88 MUTATED	3	0
MYD88 WILD-TYPE	20	18

'MYD88 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S2. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
MYD88 MUTATED	0	3
MYD88 WILD-TYPE	20	18

'MYD88 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S3. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
MYD88 MUTATED	2	1
MYD88 WILD-TYPE	13	13

'MYD88 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S4. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
MYD88 MUTATED	1	1	1
MYD88 WILD-TYPE	4	12	10

'MYD88 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S5. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
MYD88 MUTATED	1	0
MYD88 WILD-TYPE	8	12

'MYD88 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S6. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
MYD88 MUTATED	1	0	2	0
MYD88 WILD-TYPE	10	11	8	9

'MYD88 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S7. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
MYD88 MUTATED	1	0	1	1	0
MYD88 WILD-TYPE	5	11	6	11	5

'MYD88 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S8. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
MYD88 MUTATED	2	1
MYD88 WILD-TYPE	15	18

'MYD88 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S9. Gene #1: 'MYD88 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
MYD88 MUTATED	0	0	0	2	0	0	1	0	0
MYD88 WILD-TYPE	4	5	5	4	7	1	3	1	3

'FRG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 1

Table S10. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FRG1 MUTATED	6	3
FRG1 WILD-TYPE	17	15

'FRG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S11. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FRG1 MUTATED	5	4
FRG1 WILD-TYPE	15	17

'FRG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S12. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FRG1 MUTATED	5	2
FRG1 WILD-TYPE	10	12

'FRG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S13. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
FRG1 MUTATED	1	4	2
FRG1 WILD-TYPE	4	9	9

'FRG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S14. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FRG1 MUTATED	3	4
FRG1 WILD-TYPE	6	8

'FRG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S15. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FRG1 MUTATED	4	2	1
FRG1 WILD-TYPE	3	7	4

'FRG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 1

Table S16. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FRG1 MUTATED	3	3	0	3
FRG1 WILD-TYPE	8	8	10	6

'FRG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 1

Table S17. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FRG1 MUTATED	3	3	1	0	2
FRG1 WILD-TYPE	3	8	6	12	3

'FRG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S18. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FRG1 MUTATED	4	5
FRG1 WILD-TYPE	13	14

'FRG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0367 (Fisher's exact test), Q value = 1

Table S19. Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FRG1 MUTATED	2	3	0	0	3	1	0	0	0
FRG1 WILD-TYPE	2	2	5	6	4	0	4	1	3

Figure S1. Get High-res Image Gene #2: 'FRG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MLL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0969 (Fisher's exact test), Q value = 1

Table S20. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
MLL2 MUTATED	5	9
MLL2 WILD-TYPE	18	9

'MLL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S21. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
MLL2 MUTATED	5	9
MLL2 WILD-TYPE	15	12

'MLL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S22. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
MLL2 MUTATED	5	5
MLL2 WILD-TYPE	10	9

'MLL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S23. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
MLL2 MUTATED	2	4	4
MLL2 WILD-TYPE	3	9	7

'MLL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S24. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
MLL2 MUTATED	2	5
MLL2 WILD-TYPE	7	7

'MLL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.1 (Fisher's exact test), Q value = 1

Table S25. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
MLL2 MUTATED	2	5	0
MLL2 WILD-TYPE	5	4	5

'MLL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S26. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
MLL2 MUTATED	2	3	4	5
MLL2 WILD-TYPE	9	8	6	4

'MLL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S27. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
MLL2 MUTATED	1	4	1	4	4
MLL2 WILD-TYPE	5	7	6	8	1

'MLL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S28. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
MLL2 MUTATED	5	8
MLL2 WILD-TYPE	12	11

'MLL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S29. Gene #3: 'MLL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
MLL2 MUTATED	1	2	0	4	4	0	1	1	0
MLL2 WILD-TYPE	3	3	5	2	3	1	3	0	3

'TPPP MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S30. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TPPP MUTATED	3	2
TPPP WILD-TYPE	20	16

'TPPP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S31. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TPPP MUTATED	4	1
TPPP WILD-TYPE	16	20

'TPPP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S32. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TPPP MUTATED	1	2
TPPP WILD-TYPE	14	12

'TPPP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S33. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TPPP MUTATED	0	1	2
TPPP WILD-TYPE	5	12	9

'TPPP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S34. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TPPP MUTATED	1	3
TPPP WILD-TYPE	8	9

'TPPP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S35. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
TPPP MUTATED	0	3	1
TPPP WILD-TYPE	7	6	4

'TPPP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S36. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TPPP MUTATED	2	2	0	1
TPPP WILD-TYPE	9	9	10	8

'TPPP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S37. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TPPP MUTATED	1	2	0	1	1
TPPP WILD-TYPE	5	9	7	11	4

'TPPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S38. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TPPP MUTATED	1	2
TPPP WILD-TYPE	16	17

'TPPP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S39. Gene #4: 'TPPP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TPPP MUTATED	0	1	0	0	2	0	0	0	0
TPPP WILD-TYPE	4	4	5	6	5	1	4	1	3

'CHIT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S40. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CHIT1 MUTATED	3	3
CHIT1 WILD-TYPE	20	15

'CHIT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S41. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CHIT1 MUTATED	3	3
CHIT1 WILD-TYPE	17	18

'CHIT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S42. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CHIT1 MUTATED	2	3
CHIT1 WILD-TYPE	13	11

'CHIT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S43. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
CHIT1 MUTATED	1	1	3
CHIT1 WILD-TYPE	4	12	8

'CHIT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S44. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CHIT1 MUTATED	0	2
CHIT1 WILD-TYPE	9	10

'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S45. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CHIT1 MUTATED	3	1	2	0
CHIT1 WILD-TYPE	8	10	8	9

'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.827 (Fisher's exact test), Q value = 1

Table S46. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CHIT1 MUTATED	1	1	2	2	0
CHIT1 WILD-TYPE	5	10	5	10	5

'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S47. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CHIT1 MUTATED	4	1
CHIT1 WILD-TYPE	13	18

'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S48. Gene #5: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CHIT1 MUTATED	1	1	0	1	2	0	0	0	0
CHIT1 WILD-TYPE	3	4	5	5	5	1	4	1	3

'B2M MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 1

Table S49. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
B2M MUTATED	7	1
B2M WILD-TYPE	16	17

'B2M MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S50. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
B2M MUTATED	3	5
B2M WILD-TYPE	17	16

'B2M MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S51. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
B2M MUTATED	5	2
B2M WILD-TYPE	10	12

'B2M MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S52. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
B2M MUTATED	1	4	2
B2M WILD-TYPE	4	9	9

'B2M MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S53. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
B2M MUTATED	3	3
B2M WILD-TYPE	6	9

'B2M MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S54. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
B2M MUTATED	3	1	2
B2M WILD-TYPE	4	8	3

'B2M MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S55. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
B2M MUTATED	2	2	0	4
B2M WILD-TYPE	9	9	10	5

'B2M MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S56. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
B2M MUTATED	1	2	1	2	2
B2M WILD-TYPE	5	9	6	10	3

'B2M MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S57. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
B2M MUTATED	2	5
B2M WILD-TYPE	15	14

'B2M MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S58. Gene #6: 'B2M MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
B2M MUTATED	1	1	1	0	1	1	2	0	0
B2M WILD-TYPE	3	4	4	6	6	0	2	1	3

'TPTE2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S59. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TPTE2 MUTATED	6	5
TPTE2 WILD-TYPE	17	13

'TPTE2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S60. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TPTE2 MUTATED	5	6
TPTE2 WILD-TYPE	15	15

'TPTE2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S61. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TPTE2 MUTATED	1	4
TPTE2 WILD-TYPE	14	10

'TPTE2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S62. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TPTE2 MUTATED	1	1	3
TPTE2 WILD-TYPE	4	12	8

'TPTE2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S63. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TPTE2 MUTATED	2	4
TPTE2 WILD-TYPE	7	8

'TPTE2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S64. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
TPTE2 MUTATED	1	4	1
TPTE2 WILD-TYPE	6	5	4

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S65. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TPTE2 MUTATED	3	4	4	0
TPTE2 WILD-TYPE	8	7	6	9

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S66. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TPTE2 MUTATED	1	4	2	4	0
TPTE2 WILD-TYPE	5	7	5	8	5

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S67. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TPTE2 MUTATED	3	5
TPTE2 WILD-TYPE	14	14

'TPTE2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S68. Gene #7: 'TPTE2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TPTE2 MUTATED	0	1	2	2	0	0	1	1	1
TPTE2 WILD-TYPE	4	4	3	4	7	1	3	0	2

'RHPN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S69. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RHPN2 MUTATED	4	2
RHPN2 WILD-TYPE	19	16

'RHPN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S70. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RHPN2 MUTATED	3	3
RHPN2 WILD-TYPE	17	18

'RHPN2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0996 (Fisher's exact test), Q value = 1

Table S71. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RHPN2 MUTATED	4	0
RHPN2 WILD-TYPE	11	14

'RHPN2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0766 (Fisher's exact test), Q value = 1

Table S72. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
RHPN2 MUTATED	0	4	0
RHPN2 WILD-TYPE	5	9	11

'RHPN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S73. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
RHPN2 MUTATED	2	3
RHPN2 WILD-TYPE	7	9

'RHPN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S74. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
RHPN2 MUTATED	3	2	0
RHPN2 WILD-TYPE	4	7	5

'RHPN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S75. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RHPN2 MUTATED	1	1	1	3
RHPN2 WILD-TYPE	10	10	9	6

'RHPN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S76. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RHPN2 MUTATED	2	1	0	1	2
RHPN2 WILD-TYPE	4	10	7	11	3

'RHPN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S77. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RHPN2 MUTATED	2	4
RHPN2 WILD-TYPE	15	15

'RHPN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0105 (Fisher's exact test), Q value = 1

Table S78. Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RHPN2 MUTATED	0	0	0	0	3	1	0	1	1
RHPN2 WILD-TYPE	4	5	5	6	4	0	4	0	2

Figure S2. Get High-res Image Gene #8: 'RHPN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FOXD4L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S79. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FOXD4L1 MUTATED	5	2
FOXD4L1 WILD-TYPE	18	16

'FOXD4L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S80. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FOXD4L1 MUTATED	4	3
FOXD4L1 WILD-TYPE	16	18

'FOXD4L1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S81. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FOXD4L1 MUTATED	2	2
FOXD4L1 WILD-TYPE	13	12

'FOXD4L1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 1

Table S82. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
FOXD4L1 MUTATED	2	1	1
FOXD4L1 WILD-TYPE	3	12	10

'FOXD4L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S83. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FOXD4L1 MUTATED	2	2
FOXD4L1 WILD-TYPE	7	10

'FOXD4L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S84. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FOXD4L1 MUTATED	0	2	2
FOXD4L1 WILD-TYPE	7	7	3

'FOXD4L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S85. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FOXD4L1 MUTATED	2	2	1	2
FOXD4L1 WILD-TYPE	9	9	9	7

'FOXD4L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.966 (Fisher's exact test), Q value = 1

Table S86. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FOXD4L1 MUTATED	1	2	1	3	0
FOXD4L1 WILD-TYPE	5	9	6	9	5

'FOXD4L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S87. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FOXD4L1 MUTATED	1	5
FOXD4L1 WILD-TYPE	16	14

'FOXD4L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S88. Gene #9: 'FOXD4L1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FOXD4L1 MUTATED	1	1	1	1	0	0	1	1	0
FOXD4L1 WILD-TYPE	3	4	4	5	7	1	3	0	3

'DND1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S89. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
DND1 MUTATED	2	3
DND1 WILD-TYPE	21	15

'DND1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S90. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
DND1 MUTATED	2	3
DND1 WILD-TYPE	18	18

'DND1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S91. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
DND1 MUTATED	2	1
DND1 WILD-TYPE	13	13

'DND1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S92. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
DND1 MUTATED	1	2	0
DND1 WILD-TYPE	4	11	11

'DND1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S93. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
DND1 MUTATED	2	2
DND1 WILD-TYPE	7	10

'DND1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S94. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
DND1 MUTATED	0	2	2
DND1 WILD-TYPE	7	7	3

'DND1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S95. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
DND1 MUTATED	2	1	0	2
DND1 WILD-TYPE	9	10	10	7

'DND1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S96. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
DND1 MUTATED	1	1	1	1	1
DND1 WILD-TYPE	5	10	6	11	4

'DND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S97. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
DND1 MUTATED	1	3
DND1 WILD-TYPE	16	16

'DND1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S98. Gene #10: 'DND1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
DND1 MUTATED	1	1	0	0	0	0	2	0	0
DND1 WILD-TYPE	3	4	5	6	7	1	2	1	3

'ATXN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S99. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ATXN1 MUTATED	4	3
ATXN1 WILD-TYPE	19	15

'ATXN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S100. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ATXN1 MUTATED	4	3
ATXN1 WILD-TYPE	16	18

'ATXN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S101. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ATXN1 MUTATED	3	1
ATXN1 WILD-TYPE	12	13

'ATXN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S102. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
ATXN1 MUTATED	0	3	1
ATXN1 WILD-TYPE	5	10	10

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S103. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ATXN1 MUTATED	2	2
ATXN1 WILD-TYPE	7	10

'ATXN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S104. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ATXN1 MUTATED	1	2	1
ATXN1 WILD-TYPE	6	7	4

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 1

Table S105. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ATXN1 MUTATED	0	2	2	3
ATXN1 WILD-TYPE	11	9	8	6

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S106. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ATXN1 MUTATED	2	2	0	1	2
ATXN1 WILD-TYPE	4	9	7	11	3

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S107. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ATXN1 MUTATED	2	5
ATXN1 WILD-TYPE	15	14

'ATXN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S108. Gene #11: 'ATXN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ATXN1 MUTATED	0	1	0	2	2	0	1	1	0
ATXN1 WILD-TYPE	4	4	5	4	5	1	3	0	3

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0704 (Fisher's exact test), Q value = 1

Table S109. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TP53 MUTATED	1	5
TP53 WILD-TYPE	22	13

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S110. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TP53 MUTATED	2	4
TP53 WILD-TYPE	18	17

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S111. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TP53 MUTATED	2	1
TP53 WILD-TYPE	13	13

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S112. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TP53 MUTATED	1	1	1
TP53 WILD-TYPE	4	12	10

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S113. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TP53 MUTATED	2	0
TP53 WILD-TYPE	7	12

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S114. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TP53 MUTATED	2	1	0	3
TP53 WILD-TYPE	9	10	10	6

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S115. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TP53 MUTATED	1	2	2	0	1
TP53 WILD-TYPE	5	9	5	12	4

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S116. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TP53 MUTATED	2	3
TP53 WILD-TYPE	15	16

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S117. Gene #12: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TP53 MUTATED	1	1	1	0	1	0	1	0	0
TP53 WILD-TYPE	3	4	4	6	6	1	3	1	3

'CDC27 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S118. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CDC27 MUTATED	6	4
CDC27 WILD-TYPE	17	14

'CDC27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S119. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CDC27 MUTATED	6	4
CDC27 WILD-TYPE	14	17

'CDC27 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S120. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CDC27 MUTATED	4	3
CDC27 WILD-TYPE	11	11

'CDC27 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S121. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
CDC27 MUTATED	2	2	3
CDC27 WILD-TYPE	3	11	8

'CDC27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S122. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CDC27 MUTATED	3	5
CDC27 WILD-TYPE	6	7

'CDC27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S123. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CDC27 MUTATED	2	4	2
CDC27 WILD-TYPE	5	5	3

'CDC27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S124. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CDC27 MUTATED	2	3	1	4
CDC27 WILD-TYPE	9	8	9	5

'CDC27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.044 (Fisher's exact test), Q value = 1

Table S125. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CDC27 MUTATED	1	3	1	1	4
CDC27 WILD-TYPE	5	8	6	11	1

Figure S3. Get High-res Image Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0652 (Fisher's exact test), Q value = 1

Table S126. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CDC27 MUTATED	2	8
CDC27 WILD-TYPE	15	11

'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S127. Gene #13: 'CDC27 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CDC27 MUTATED	1	2	0	0	3	0	2	1	1
CDC27 WILD-TYPE	3	3	5	6	4	1	2	0	2

'EPB41L4A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S128. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
EPB41L4A MUTATED	3	1
EPB41L4A WILD-TYPE	20	17

'EPB41L4A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S129. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
EPB41L4A MUTATED	3	1
EPB41L4A WILD-TYPE	17	20

'EPB41L4A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S130. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
EPB41L4A MUTATED	1	2
EPB41L4A WILD-TYPE	14	12

'EPB41L4A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S131. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
EPB41L4A MUTATED	0	1	2
EPB41L4A WILD-TYPE	5	12	9

'EPB41L4A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S132. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
EPB41L4A MUTATED	0	2
EPB41L4A WILD-TYPE	9	10

'EPB41L4A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S133. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
EPB41L4A MUTATED	0	2	1	1
EPB41L4A WILD-TYPE	11	9	9	8

'EPB41L4A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S134. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
EPB41L4A MUTATED	0	2	0	1	1
EPB41L4A WILD-TYPE	6	9	7	11	4

'EPB41L4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S135. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
EPB41L4A MUTATED	1	3
EPB41L4A WILD-TYPE	16	16

'EPB41L4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.983 (Fisher's exact test), Q value = 1

Table S136. Gene #14: 'EPB41L4A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
EPB41L4A MUTATED	1	1	0	1	1	0	0	0	0
EPB41L4A WILD-TYPE	3	4	5	5	6	1	4	1	3

'NOTCH2NL MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S137. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
NOTCH2NL MUTATED	2	2
NOTCH2NL WILD-TYPE	21	16

'NOTCH2NL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S138. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
NOTCH2NL MUTATED	3	1
NOTCH2NL WILD-TYPE	17	20

'NOTCH2NL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S139. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
NOTCH2NL MUTATED	0	1
NOTCH2NL WILD-TYPE	15	13

'NOTCH2NL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S140. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
NOTCH2NL MUTATED	0	1
NOTCH2NL WILD-TYPE	9	11

'NOTCH2NL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S141. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
NOTCH2NL MUTATED	1	2	1	0
NOTCH2NL WILD-TYPE	10	9	9	9

'NOTCH2NL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S142. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
NOTCH2NL MUTATED	0	2	1	1	0
NOTCH2NL WILD-TYPE	6	9	6	11	5

'NOTCH2NL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S143. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
NOTCH2NL MUTATED	1	3
NOTCH2NL WILD-TYPE	16	16

'NOTCH2NL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S144. Gene #15: 'NOTCH2NL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
NOTCH2NL MUTATED	0	1	1	0	0	0	0	1	1
NOTCH2NL WILD-TYPE	4	4	4	6	7	1	4	0	2

'KRT3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S145. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KRT3 MUTATED	2	2
KRT3 WILD-TYPE	21	16

'KRT3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S146. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KRT3 MUTATED	2	2
KRT3 WILD-TYPE	18	19

'KRT3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S147. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KRT3 MUTATED	0	2
KRT3 WILD-TYPE	15	12

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S148. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KRT3 MUTATED	0	2
KRT3 WILD-TYPE	9	10

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S149. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KRT3 MUTATED	1	2	1	0
KRT3 WILD-TYPE	10	9	9	9

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S150. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KRT3 MUTATED	0	2	1	1	0
KRT3 WILD-TYPE	6	9	6	11	5

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S151. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KRT3 MUTATED	2	2
KRT3 WILD-TYPE	15	17

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S152. Gene #16: 'KRT3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KRT3 MUTATED	1	0	0	1	1	0	0	1	0
KRT3 WILD-TYPE	3	5	5	5	6	1	4	0	3

'OR1S2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S153. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OR1S2 MUTATED	7	3
OR1S2 WILD-TYPE	16	15

'OR1S2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S154. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OR1S2 MUTATED	5	5
OR1S2 WILD-TYPE	15	16

'OR1S2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S155. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OR1S2 MUTATED	4	2
OR1S2 WILD-TYPE	11	12

'OR1S2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S156. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
OR1S2 MUTATED	2	2	2
OR1S2 WILD-TYPE	3	11	9

'OR1S2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S157. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OR1S2 MUTATED	3	2
OR1S2 WILD-TYPE	6	10

'OR1S2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S158. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
OR1S2 MUTATED	1	2	2
OR1S2 WILD-TYPE	6	7	3

'OR1S2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S159. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OR1S2 MUTATED	4	2	3	1
OR1S2 WILD-TYPE	7	9	7	8

'OR1S2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S160. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OR1S2 MUTATED	2	2	2	4	0
OR1S2 WILD-TYPE	4	9	5	8	5

'OR1S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S161. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OR1S2 MUTATED	5	3
OR1S2 WILD-TYPE	12	16

'OR1S2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S162. Gene #17: 'OR1S2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OR1S2 MUTATED	1	1	0	1	2	0	1	1	1
OR1S2 WILD-TYPE	3	4	5	5	5	1	3	0	2

'RGPD5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0563 (Fisher's exact test), Q value = 1

Table S163. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RGPD5 MUTATED	5	0
RGPD5 WILD-TYPE	18	18

'RGPD5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S164. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RGPD5 MUTATED	4	1
RGPD5 WILD-TYPE	16	20

'RGPD5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S165. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RGPD5 MUTATED	2	2
RGPD5 WILD-TYPE	13	12

'RGPD5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 1

Table S166. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
RGPD5 MUTATED	2	1	1
RGPD5 WILD-TYPE	3	12	10

'RGPD5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S167. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
RGPD5 MUTATED	1	1
RGPD5 WILD-TYPE	8	11

'RGPD5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S168. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RGPD5 MUTATED	1	1	2	1
RGPD5 WILD-TYPE	10	10	8	8

'RGPD5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S169. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RGPD5 MUTATED	1	1	0	3	0
RGPD5 WILD-TYPE	5	10	7	9	5

'RGPD5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S170. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RGPD5 MUTATED	2	3
RGPD5 WILD-TYPE	15	16

'RGPD5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 1

Table S171. Gene #18: 'RGPD5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RGPD5 MUTATED	1	0	2	1	0	0	0	1	0
RGPD5 WILD-TYPE	3	5	3	5	7	1	4	0	3

'TNFAIP3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0266 (Fisher's exact test), Q value = 1

Table S172. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TNFAIP3 MUTATED	6	0
TNFAIP3 WILD-TYPE	17	18

Figure S4. Get High-res Image Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TNFAIP3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S173. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TNFAIP3 MUTATED	3	3
TNFAIP3 WILD-TYPE	17	18

'TNFAIP3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S174. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TNFAIP3 MUTATED	2	3
TNFAIP3 WILD-TYPE	13	11

'TNFAIP3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S175. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TNFAIP3 MUTATED	0	3	2
TNFAIP3 WILD-TYPE	5	10	9

'TNFAIP3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S176. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TNFAIP3 MUTATED	0	2
TNFAIP3 WILD-TYPE	9	10

'TNFAIP3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S177. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TNFAIP3 MUTATED	0	3	2	1
TNFAIP3 WILD-TYPE	11	8	8	8

'TNFAIP3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S178. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TNFAIP3 MUTATED	1	3	0	1	1
TNFAIP3 WILD-TYPE	5	8	7	11	4

'TNFAIP3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S179. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TNFAIP3 MUTATED	1	4
TNFAIP3 WILD-TYPE	16	15

'TNFAIP3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0232 (Fisher's exact test), Q value = 1

Table S180. Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TNFAIP3 MUTATED	0	1	0	2	0	1	0	1	0
TNFAIP3 WILD-TYPE	4	4	5	4	7	0	4	0	3

Figure S5. Get High-res Image Gene #19: 'TNFAIP3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RBMXL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S181. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RBMXL1 MUTATED	2	2
RBMXL1 WILD-TYPE	21	16

'RBMXL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S182. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RBMXL1 MUTATED	3	1
RBMXL1 WILD-TYPE	17	20

'RBMXL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S183. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RBMXL1 MUTATED	2	1
RBMXL1 WILD-TYPE	13	13

'RBMXL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S184. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
RBMXL1 MUTATED	0	2	1
RBMXL1 WILD-TYPE	5	11	10

'RBMXL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S185. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
RBMXL1 MUTATED	1	1
RBMXL1 WILD-TYPE	8	11

'RBMXL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S186. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RBMXL1 MUTATED	2	1	1	0
RBMXL1 WILD-TYPE	9	10	9	9

'RBMXL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S187. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RBMXL1 MUTATED	2	1	0	1	0
RBMXL1 WILD-TYPE	4	10	7	11	5

'RBMXL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S188. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RBMXL1 MUTATED	2	2
RBMXL1 WILD-TYPE	15	17

'RBMXL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S189. Gene #20: 'RBMXL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RBMXL1 MUTATED	0	1	0	0	2	0	0	0	1
RBMXL1 WILD-TYPE	4	4	5	6	5	1	4	1	2

'CCDC66 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S190. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CCDC66 MUTATED	2	2
CCDC66 WILD-TYPE	21	16

'CCDC66 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0478 (Fisher's exact test), Q value = 1

Table S191. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CCDC66 MUTATED	4	0
CCDC66 WILD-TYPE	16	21

Figure S6. Get High-res Image Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CCDC66 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S192. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CCDC66 MUTATED	0	2
CCDC66 WILD-TYPE	15	12

'CCDC66 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S193. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CCDC66 MUTATED	0	4
CCDC66 WILD-TYPE	9	8

'CCDC66 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0553 (Fisher's exact test), Q value = 1

Table S194. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CCDC66 MUTATED	0	4	0
CCDC66 WILD-TYPE	7	5	5

'CCDC66 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S195. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CCDC66 MUTATED	0	3	0	1
CCDC66 WILD-TYPE	11	8	10	8

'CCDC66 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S196. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CCDC66 MUTATED	0	3	0	0	1
CCDC66 WILD-TYPE	6	8	7	12	4

'CCDC66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S197. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CCDC66 MUTATED	0	3
CCDC66 WILD-TYPE	17	16

'CCDC66 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S198. Gene #21: 'CCDC66 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CCDC66 MUTATED	0	1	0	0	1	0	0	1	0
CCDC66 WILD-TYPE	4	4	5	6	6	1	4	0	3

'NOTCH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S199. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
NOTCH2 MUTATED	5	2
NOTCH2 WILD-TYPE	18	16

'NOTCH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S200. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
NOTCH2 MUTATED	3	4
NOTCH2 WILD-TYPE	17	17

'NOTCH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S201. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
NOTCH2 MUTATED	2	2
NOTCH2 WILD-TYPE	13	12

'NOTCH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S202. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
NOTCH2 MUTATED	1	2	1
NOTCH2 WILD-TYPE	4	11	10

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S203. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
NOTCH2 MUTATED	1	4
NOTCH2 WILD-TYPE	8	8

'NOTCH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.183 (Fisher's exact test), Q value = 1

Table S204. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
NOTCH2 MUTATED	0	3	2
NOTCH2 WILD-TYPE	7	6	3

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S205. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
NOTCH2 MUTATED	2	3	1	1
NOTCH2 WILD-TYPE	9	8	9	8

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S206. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
NOTCH2 MUTATED	1	3	1	1	1
NOTCH2 WILD-TYPE	5	8	6	11	4

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S207. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
NOTCH2 MUTATED	2	4
NOTCH2 WILD-TYPE	15	15

'NOTCH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.276 (Fisher's exact test), Q value = 1

Table S208. Gene #22: 'NOTCH2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
NOTCH2 MUTATED	0	3	1	1	0	0	1	0	0
NOTCH2 WILD-TYPE	4	2	4	5	7	1	3	1	3

'PCMTD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S209. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PCMTD1 MUTATED	3	3
PCMTD1 WILD-TYPE	20	15

'PCMTD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S210. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PCMTD1 MUTATED	3	3
PCMTD1 WILD-TYPE	17	18

'PCMTD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S211. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PCMTD1 MUTATED	2	3
PCMTD1 WILD-TYPE	13	11

'PCMTD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S212. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PCMTD1 MUTATED	0	2	3
PCMTD1 WILD-TYPE	5	11	8

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S213. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PCMTD1 MUTATED	2	3
PCMTD1 WILD-TYPE	7	9

'PCMTD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 1

Table S214. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PCMTD1 MUTATED	3	2	0
PCMTD1 WILD-TYPE	4	7	5

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S215. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PCMTD1 MUTATED	2	3	0	1
PCMTD1 WILD-TYPE	9	8	10	8

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S216. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PCMTD1 MUTATED	1	3	1	0	1
PCMTD1 WILD-TYPE	5	8	6	12	4

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S217. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PCMTD1 MUTATED	2	4
PCMTD1 WILD-TYPE	15	15

'PCMTD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S218. Gene #23: 'PCMTD1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PCMTD1 MUTATED	1	1	1	0	1	0	1	1	0
PCMTD1 WILD-TYPE	3	4	4	6	6	1	3	0	3

'FAM120B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S219. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FAM120B MUTATED	3	2
FAM120B WILD-TYPE	20	16

'FAM120B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S220. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FAM120B MUTATED	2	3
FAM120B WILD-TYPE	18	18

'FAM120B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S221. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FAM120B MUTATED	3	0
FAM120B WILD-TYPE	12	14

'FAM120B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S222. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
FAM120B MUTATED	0	3	0
FAM120B WILD-TYPE	5	10	11

'FAM120B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S223. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FAM120B MUTATED	2	2
FAM120B WILD-TYPE	7	10

'FAM120B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S224. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FAM120B MUTATED	1	2	1
FAM120B WILD-TYPE	6	7	4

'FAM120B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S225. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FAM120B MUTATED	3	1	1	0
FAM120B WILD-TYPE	8	10	9	9

'FAM120B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0848 (Fisher's exact test), Q value = 1

Table S226. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FAM120B MUTATED	3	1	0	1	0
FAM120B WILD-TYPE	3	10	7	11	5

'FAM120B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S227. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FAM120B MUTATED	3	1
FAM120B WILD-TYPE	14	18

'FAM120B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S228. Gene #24: 'FAM120B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FAM120B MUTATED	0	0	0	1	2	0	1	0	0
FAM120B WILD-TYPE	4	5	5	5	5	1	3	1	3

'SMARCA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S229. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
SMARCA2 MUTATED	2	2
SMARCA2 WILD-TYPE	21	16

'SMARCA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S230. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
SMARCA2 MUTATED	3	1
SMARCA2 WILD-TYPE	17	20

'SMARCA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S231. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
SMARCA2 MUTATED	0	2
SMARCA2 WILD-TYPE	15	12

'SMARCA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S232. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
SMARCA2 MUTATED	1	3
SMARCA2 WILD-TYPE	8	9

'SMARCA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.504 (Fisher's exact test), Q value = 1

Table S233. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
SMARCA2 MUTATED	1	1	2
SMARCA2 WILD-TYPE	6	8	3

'SMARCA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S234. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
SMARCA2 MUTATED	0	2	0	2
SMARCA2 WILD-TYPE	11	9	10	7

'SMARCA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S235. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
SMARCA2 MUTATED	1	2	0	0	1
SMARCA2 WILD-TYPE	5	9	7	12	4

'SMARCA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S236. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
SMARCA2 MUTATED	0	4
SMARCA2 WILD-TYPE	17	15

'SMARCA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S237. Gene #25: 'SMARCA2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
SMARCA2 MUTATED	1	1	0	0	1	0	1	0	0
SMARCA2 WILD-TYPE	3	4	5	6	6	1	3	1	3

'C11ORF40 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S238. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
C11ORF40 MUTATED	2	2
C11ORF40 WILD-TYPE	21	16

'C11ORF40 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S239. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
C11ORF40 MUTATED	2	2
C11ORF40 WILD-TYPE	18	19

'C11ORF40 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S240. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
C11ORF40 MUTATED	1	1
C11ORF40 WILD-TYPE	14	13

'C11ORF40 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S241. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
C11ORF40 MUTATED	0	1
C11ORF40 WILD-TYPE	9	11

'C11ORF40 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S242. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
C11ORF40 MUTATED	1	1	2	0
C11ORF40 WILD-TYPE	10	10	8	9

'C11ORF40 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S243. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
C11ORF40 MUTATED	0	1	1	2	0
C11ORF40 WILD-TYPE	6	10	6	10	5

'C11ORF40 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S244. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
C11ORF40 MUTATED	2	1
C11ORF40 WILD-TYPE	15	18

'C11ORF40 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S245. Gene #26: 'C11ORF40 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
C11ORF40 MUTATED	1	0	0	1	0	0	0	1	0
C11ORF40 WILD-TYPE	3	5	5	5	7	1	4	0	3

'ZSCAN5A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S246. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ZSCAN5A MUTATED	1	2
ZSCAN5A WILD-TYPE	22	16

'ZSCAN5A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S247. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ZSCAN5A MUTATED	3	0
ZSCAN5A WILD-TYPE	17	21

'ZSCAN5A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S248. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ZSCAN5A MUTATED	0	2
ZSCAN5A WILD-TYPE	9	10

'ZSCAN5A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S249. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ZSCAN5A MUTATED	0	2	0	1
ZSCAN5A WILD-TYPE	11	9	10	8

'ZSCAN5A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S250. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ZSCAN5A MUTATED	0	1	0	1	1
ZSCAN5A WILD-TYPE	6	10	7	11	4

'ZSCAN5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S251. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ZSCAN5A MUTATED	0	3
ZSCAN5A WILD-TYPE	17	16

'ZSCAN5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S252. Gene #27: 'ZSCAN5A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ZSCAN5A MUTATED	0	0	0	0	1	0	1	0	1
ZSCAN5A WILD-TYPE	4	5	5	6	6	1	3	1	2

'KRTAP4-5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S253. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KRTAP4-5 MUTATED	2	2
KRTAP4-5 WILD-TYPE	21	16

'KRTAP4-5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S254. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KRTAP4-5 MUTATED	3	1
KRTAP4-5 WILD-TYPE	17	20

'KRTAP4-5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S255. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KRTAP4-5 MUTATED	1	0
KRTAP4-5 WILD-TYPE	14	14

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S256. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KRTAP4-5 MUTATED	2	2
KRTAP4-5 WILD-TYPE	7	10

'KRTAP4-5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S257. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KRTAP4-5 MUTATED	0	2	2
KRTAP4-5 WILD-TYPE	7	7	3

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S258. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KRTAP4-5 MUTATED	1	1	0	2
KRTAP4-5 WILD-TYPE	10	10	10	7

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S259. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KRTAP4-5 MUTATED	1	1	1	0	1
KRTAP4-5 WILD-TYPE	5	10	6	12	4

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S260. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KRTAP4-5 MUTATED	1	3
KRTAP4-5 WILD-TYPE	16	16

'KRTAP4-5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0479 (Fisher's exact test), Q value = 1

Table S261. Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KRTAP4-5 MUTATED	0	0	0	0	1	0	2	1	0
KRTAP4-5 WILD-TYPE	4	5	5	6	6	1	2	0	3

Figure S7. Get High-res Image Gene #28: 'KRTAP4-5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'DEFA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S262. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
DEFA1 MUTATED	2	2
DEFA1 WILD-TYPE	21	16

'DEFA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S263. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
DEFA1 MUTATED	2	2
DEFA1 WILD-TYPE	18	19

'DEFA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S264. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
DEFA1 MUTATED	1	1
DEFA1 WILD-TYPE	14	13

'DEFA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S265. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
DEFA1 MUTATED	0	3
DEFA1 WILD-TYPE	9	9

'DEFA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 1

Table S266. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
DEFA1 MUTATED	0	3	0
DEFA1 WILD-TYPE	7	6	5

'DEFA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S267. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
DEFA1 MUTATED	0	1	1	2
DEFA1 WILD-TYPE	11	10	9	7

'DEFA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 1

Table S268. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
DEFA1 MUTATED	0	1	0	1	2
DEFA1 WILD-TYPE	6	10	7	11	3

'DEFA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S269. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
DEFA1 MUTATED	0	4
DEFA1 WILD-TYPE	17	15

'DEFA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S270. Gene #29: 'DEFA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
DEFA1 MUTATED	0	0	0	1	1	0	1	1	0
DEFA1 WILD-TYPE	4	5	5	5	6	1	3	0	3

'SIRPA MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S271. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
SIRPA MUTATED	3	2
SIRPA WILD-TYPE	20	16

'SIRPA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S272. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
SIRPA MUTATED	3	2
SIRPA WILD-TYPE	17	19

'SIRPA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S273. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
SIRPA MUTATED	1	2
SIRPA WILD-TYPE	14	12

'SIRPA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S274. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
SIRPA MUTATED	0	1	2
SIRPA WILD-TYPE	5	12	9

'SIRPA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S275. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
SIRPA MUTATED	1	4
SIRPA WILD-TYPE	8	8

'SIRPA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S276. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
SIRPA MUTATED	2	3	0
SIRPA WILD-TYPE	5	6	5

'SIRPA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S277. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
SIRPA MUTATED	1	2	0	2
SIRPA WILD-TYPE	10	9	10	7

'SIRPA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 1

Table S278. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
SIRPA MUTATED	0	2	1	0	2
SIRPA WILD-TYPE	6	9	6	12	3

'SIRPA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S279. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
SIRPA MUTATED	1	4
SIRPA WILD-TYPE	16	15

'SIRPA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.083 (Fisher's exact test), Q value = 1

Table S280. Gene #30: 'SIRPA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
SIRPA MUTATED	0	1	1	0	1	1	0	1	0
SIRPA WILD-TYPE	4	4	4	6	6	0	4	0	3

'TMPRSS13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S281. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TMPRSS13 MUTATED	1	2
TMPRSS13 WILD-TYPE	22	16

'TMPRSS13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S282. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TMPRSS13 MUTATED	2	1
TMPRSS13 WILD-TYPE	18	20

'TMPRSS13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S283. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TMPRSS13 MUTATED	1	1
TMPRSS13 WILD-TYPE	14	13

'TMPRSS13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S284. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TMPRSS13 MUTATED	1	2
TMPRSS13 WILD-TYPE	8	10

'TMPRSS13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S285. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
TMPRSS13 MUTATED	1	2	0
TMPRSS13 WILD-TYPE	6	7	5

'TMPRSS13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S286. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TMPRSS13 MUTATED	1	0	0	2
TMPRSS13 WILD-TYPE	10	11	10	7

'TMPRSS13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0114 (Fisher's exact test), Q value = 1

Table S287. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TMPRSS13 MUTATED	1	0	0	0	2
TMPRSS13 WILD-TYPE	5	11	7	12	3

Figure S8. Get High-res Image Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'TMPRSS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S288. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TMPRSS13 MUTATED	1	2
TMPRSS13 WILD-TYPE	16	17

'TMPRSS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S289. Gene #31: 'TMPRSS13 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TMPRSS13 MUTATED	1	0	0	0	2	0	0	0	0
TMPRSS13 WILD-TYPE	3	5	5	6	5	1	4	1	3

'CYP2A6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S290. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CYP2A6 MUTATED	1	3
CYP2A6 WILD-TYPE	22	15

'CYP2A6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S291. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CYP2A6 MUTATED	2	2
CYP2A6 WILD-TYPE	18	19

'CYP2A6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S292. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CYP2A6 MUTATED	1	1
CYP2A6 WILD-TYPE	14	13

'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S293. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CYP2A6 MUTATED	1	2
CYP2A6 WILD-TYPE	8	10

'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.762 (Fisher's exact test), Q value = 1

Table S294. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CYP2A6 MUTATED	1	2	0
CYP2A6 WILD-TYPE	6	7	5

'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0173 (Fisher's exact test), Q value = 1

Table S295. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CYP2A6 MUTATED	0	0	1	3
CYP2A6 WILD-TYPE	11	11	9	6

Figure S9. Get High-res Image Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0784 (Fisher's exact test), Q value = 1

Table S296. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CYP2A6 MUTATED	1	0	0	1	2
CYP2A6 WILD-TYPE	5	11	7	11	3

'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S297. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CYP2A6 MUTATED	1	3
CYP2A6 WILD-TYPE	16	16

'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S298. Gene #32: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CYP2A6 MUTATED	0	0	0	0	3	0	0	0	1
CYP2A6 WILD-TYPE	4	5	5	6	4	1	4	1	2

'AR MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S299. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
AR MUTATED	4	3
AR WILD-TYPE	19	15

'AR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S300. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
AR MUTATED	4	3
AR WILD-TYPE	16	18

'AR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0996 (Fisher's exact test), Q value = 1

Table S301. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
AR MUTATED	4	0
AR WILD-TYPE	11	14

'AR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0781 (Fisher's exact test), Q value = 1

Table S302. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
AR MUTATED	0	4	0
AR WILD-TYPE	5	9	11

'AR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S303. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
AR MUTATED	1	4
AR WILD-TYPE	8	8

'AR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S304. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
AR MUTATED	1	3	1
AR WILD-TYPE	6	6	4

'AR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 1

Table S305. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
AR MUTATED	2	2	0	3
AR WILD-TYPE	9	9	10	6

'AR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S306. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
AR MUTATED	1	3	1	1	1
AR WILD-TYPE	5	8	6	11	4

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S307. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
AR MUTATED	2	4
AR WILD-TYPE	15	15

'AR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0437 (Fisher's exact test), Q value = 1

Table S308. Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
AR MUTATED	0	0	2	0	1	1	1	1	0
AR WILD-TYPE	4	5	3	6	6	0	3	0	3

Figure S10. Get High-res Image Gene #33: 'AR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARHGEF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S309. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ARHGEF5 MUTATED	2	1
ARHGEF5 WILD-TYPE	21	17

'ARHGEF5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S310. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ARHGEF5 MUTATED	1	2
ARHGEF5 WILD-TYPE	19	19

'ARHGEF5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S311. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ARHGEF5 MUTATED	1	0
ARHGEF5 WILD-TYPE	14	14

'ARHGEF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S312. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ARHGEF5 MUTATED	1	2
ARHGEF5 WILD-TYPE	8	10

'ARHGEF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S313. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ARHGEF5 MUTATED	0	2	1
ARHGEF5 WILD-TYPE	7	7	4

'ARHGEF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S314. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ARHGEF5 MUTATED	1	1	0	1
ARHGEF5 WILD-TYPE	10	10	10	8

'ARHGEF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S315. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ARHGEF5 MUTATED	0	1	0	1	1
ARHGEF5 WILD-TYPE	6	10	7	11	4

'ARHGEF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S316. Gene #34: 'ARHGEF5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ARHGEF5 MUTATED	0	2
ARHGEF5 WILD-TYPE	17	17

'RNF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S317. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RNF39 MUTATED	1	2
RNF39 WILD-TYPE	22	16

'RNF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S318. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RNF39 MUTATED	2	1
RNF39 WILD-TYPE	18	20

'RNF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S319. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RNF39 MUTATED	0	1
RNF39 WILD-TYPE	15	13

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S320. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
RNF39 MUTATED	1	2
RNF39 WILD-TYPE	8	10

'RNF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S321. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
RNF39 MUTATED	1	2	0
RNF39 WILD-TYPE	6	7	5

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S322. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RNF39 MUTATED	1	1	0	1
RNF39 WILD-TYPE	10	10	10	8

'RNF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S323. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RNF39 MUTATED	0	1	1	0	1
RNF39 WILD-TYPE	6	10	6	12	4

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S324. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RNF39 MUTATED	1	2
RNF39 WILD-TYPE	16	17

'RNF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S325. Gene #35: 'RNF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RNF39 MUTATED	0	0	1	0	1	0	0	1	0
RNF39 WILD-TYPE	4	5	4	6	6	1	4	0	3

'ABCA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S326. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ABCA1 MUTATED	2	3
ABCA1 WILD-TYPE	21	15

'ABCA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S327. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ABCA1 MUTATED	3	2
ABCA1 WILD-TYPE	17	19

'ABCA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S328. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ABCA1 MUTATED	1	1
ABCA1 WILD-TYPE	14	13

'ABCA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S329. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ABCA1 MUTATED	2	2
ABCA1 WILD-TYPE	7	10

'ABCA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S330. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ABCA1 MUTATED	0	2	2
ABCA1 WILD-TYPE	7	7	3

'ABCA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S331. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ABCA1 MUTATED	2	1	1	1
ABCA1 WILD-TYPE	9	10	9	8

'ABCA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S332. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ABCA1 MUTATED	0	1	1	2	1
ABCA1 WILD-TYPE	6	10	6	10	4

'ABCA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S333. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ABCA1 MUTATED	2	2
ABCA1 WILD-TYPE	15	17

'ABCA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S334. Gene #36: 'ABCA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ABCA1 MUTATED	0	0	1	1	1	0	0	1	0
ABCA1 WILD-TYPE	4	5	4	5	6	1	4	0	3

'CS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S335. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CS MUTATED	2	1
CS WILD-TYPE	21	17

'CS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S336. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CS MUTATED	3	0
CS WILD-TYPE	17	21

'CS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S337. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CS MUTATED	0	1
CS WILD-TYPE	15	13

'CS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S338. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CS MUTATED	1	1
CS WILD-TYPE	8	11

'CS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S339. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CS MUTATED	0	2	0	1
CS WILD-TYPE	11	9	10	8

'CS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S340. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CS MUTATED	1	2	0	0	0
CS WILD-TYPE	5	9	7	12	5

'CS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S341. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CS MUTATED	0	3
CS WILD-TYPE	17	16

'CS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0877 (Fisher's exact test), Q value = 1

Table S342. Gene #37: 'CS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CS MUTATED	0	1	0	0	0	0	1	1	0
CS WILD-TYPE	4	4	5	6	7	1	3	0	3

'IFITM3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S343. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
IFITM3 MUTATED	3	1
IFITM3 WILD-TYPE	20	17

'IFITM3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S344. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
IFITM3 MUTATED	2	2
IFITM3 WILD-TYPE	18	19

'IFITM3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S345. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
IFITM3 MUTATED	3	0
IFITM3 WILD-TYPE	12	14

'IFITM3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S346. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
IFITM3 MUTATED	0	3	0
IFITM3 WILD-TYPE	5	10	11

'IFITM3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S347. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
IFITM3 MUTATED	1	3
IFITM3 WILD-TYPE	8	9

'IFITM3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S348. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
IFITM3 MUTATED	2	2	0
IFITM3 WILD-TYPE	5	7	5

'IFITM3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S349. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
IFITM3 MUTATED	1	1	0	2
IFITM3 WILD-TYPE	10	10	10	7

'IFITM3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0717 (Fisher's exact test), Q value = 1

Table S350. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
IFITM3 MUTATED	1	1	0	0	2
IFITM3 WILD-TYPE	5	10	7	12	3

'IFITM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S351. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
IFITM3 MUTATED	1	3
IFITM3 WILD-TYPE	16	16

'IFITM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0146 (Fisher's exact test), Q value = 1

Table S352. Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
IFITM3 MUTATED	0	0	0	0	2	1	0	1	0
IFITM3 WILD-TYPE	4	5	5	6	5	0	4	0	3

Figure S11. Get High-res Image Gene #38: 'IFITM3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RANBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S353. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RANBP2 MUTATED	3	3
RANBP2 WILD-TYPE	20	15

'RANBP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S354. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RANBP2 MUTATED	3	3
RANBP2 WILD-TYPE	17	18

'RANBP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S355. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RANBP2 MUTATED	2	3
RANBP2 WILD-TYPE	13	11

'RANBP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S356. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
RANBP2 MUTATED	1	2	2
RANBP2 WILD-TYPE	4	11	9

'RANBP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S357. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
RANBP2 MUTATED	0	3
RANBP2 WILD-TYPE	9	9

'RANBP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S358. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
RANBP2 MUTATED	0	3	0
RANBP2 WILD-TYPE	7	6	5

'RANBP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S359. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RANBP2 MUTATED	1	2	1	2
RANBP2 WILD-TYPE	10	9	9	7

'RANBP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S360. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RANBP2 MUTATED	0	2	1	1	2
RANBP2 WILD-TYPE	6	9	6	11	3

'RANBP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S361. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RANBP2 MUTATED	2	4
RANBP2 WILD-TYPE	15	15

'RANBP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S362. Gene #39: 'RANBP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RANBP2 MUTATED	1	1	1	0	1	0	1	1	0
RANBP2 WILD-TYPE	3	4	4	6	6	1	3	0	3

'KLHL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S363. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KLHL6 MUTATED	2	4
KLHL6 WILD-TYPE	21	14

'KLHL6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S364. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KLHL6 MUTATED	3	3
KLHL6 WILD-TYPE	17	18

'KLHL6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S365. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KLHL6 MUTATED	1	3
KLHL6 WILD-TYPE	14	11

'KLHL6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.359 (Fisher's exact test), Q value = 1

Table S366. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
KLHL6 MUTATED	0	1	3
KLHL6 WILD-TYPE	5	12	8

'KLHL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S367. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KLHL6 MUTATED	1	4
KLHL6 WILD-TYPE	8	8

'KLHL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S368. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KLHL6 MUTATED	1	3	1
KLHL6 WILD-TYPE	6	6	4

'KLHL6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S369. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KLHL6 MUTATED	1	2	1	2
KLHL6 WILD-TYPE	10	9	9	7

'KLHL6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S370. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KLHL6 MUTATED	0	2	0	2	2
KLHL6 WILD-TYPE	6	9	7	10	3

'KLHL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S371. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KLHL6 MUTATED	1	4
KLHL6 WILD-TYPE	16	15

'KLHL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S372. Gene #40: 'KLHL6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KLHL6 MUTATED	1	0	0	1	1	0	2	0	0
KLHL6 WILD-TYPE	3	5	5	5	6	1	2	1	3

'ZNF814 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S373. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ZNF814 MUTATED	8	2
ZNF814 WILD-TYPE	15	16

'ZNF814 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S374. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ZNF814 MUTATED	6	4
ZNF814 WILD-TYPE	14	17

'ZNF814 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S375. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ZNF814 MUTATED	4	2
ZNF814 WILD-TYPE	11	12

'ZNF814 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S376. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
ZNF814 MUTATED	1	4	1
ZNF814 WILD-TYPE	4	9	10

'ZNF814 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S377. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ZNF814 MUTATED	0	3
ZNF814 WILD-TYPE	9	9

'ZNF814 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S378. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ZNF814 MUTATED	1	2	0
ZNF814 WILD-TYPE	6	7	5

'ZNF814 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0506 (Fisher's exact test), Q value = 1

Table S379. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ZNF814 MUTATED	0	3	5	2
ZNF814 WILD-TYPE	11	8	5	7

'ZNF814 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0193 (Fisher's exact test), Q value = 1

Table S380. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ZNF814 MUTATED	0	2	0	7	1
ZNF814 WILD-TYPE	6	9	7	5	4

Figure S12. Get High-res Image Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'ZNF814 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S381. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ZNF814 MUTATED	3	5
ZNF814 WILD-TYPE	14	14

'ZNF814 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0122 (Fisher's exact test), Q value = 1

Table S382. Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ZNF814 MUTATED	0	0	2	2	0	1	0	1	2
ZNF814 WILD-TYPE	4	5	3	4	7	0	4	0	1

Figure S13. Get High-res Image Gene #41: 'ZNF814 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CYP4A11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S383. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CYP4A11 MUTATED	3	1
CYP4A11 WILD-TYPE	20	17

'CYP4A11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S384. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CYP4A11 MUTATED	2	2
CYP4A11 WILD-TYPE	18	19

'CYP4A11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S385. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CYP4A11 MUTATED	3	0
CYP4A11 WILD-TYPE	12	14

'CYP4A11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S386. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
CYP4A11 MUTATED	0	3	0
CYP4A11 WILD-TYPE	5	10	11

'CYP4A11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S387. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CYP4A11 MUTATED	2	2
CYP4A11 WILD-TYPE	7	10

'CYP4A11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S388. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CYP4A11 MUTATED	1	2	1
CYP4A11 WILD-TYPE	6	7	4

'CYP4A11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S389. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CYP4A11 MUTATED	2	1	0	1
CYP4A11 WILD-TYPE	9	10	10	8

'CYP4A11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S390. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CYP4A11 MUTATED	2	1	1	0	0
CYP4A11 WILD-TYPE	4	10	6	12	5

'CYP4A11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S391. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CYP4A11 MUTATED	3	1
CYP4A11 WILD-TYPE	14	18

'CYP4A11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S392. Gene #42: 'CYP4A11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CYP4A11 MUTATED	0	0	1	0	2	0	0	1	0
CYP4A11 WILD-TYPE	4	5	4	6	5	1	4	0	3

'PIM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S393. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PIM1 MUTATED	5	3
PIM1 WILD-TYPE	18	15

'PIM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00345 (Fisher's exact test), Q value = 1

Table S394. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PIM1 MUTATED	0	8
PIM1 WILD-TYPE	20	13

Figure S14. Get High-res Image Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'PIM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S395. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PIM1 MUTATED	4	2
PIM1 WILD-TYPE	11	12

'PIM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S396. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PIM1 MUTATED	1	3	2
PIM1 WILD-TYPE	4	10	9

'PIM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.171 (Fisher's exact test), Q value = 1

Table S397. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PIM1 MUTATED	2	0
PIM1 WILD-TYPE	7	12

'PIM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0995 (Fisher's exact test), Q value = 1

Table S398. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PIM1 MUTATED	3	0	4	1
PIM1 WILD-TYPE	8	11	6	8

'PIM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0745 (Fisher's exact test), Q value = 1

Table S399. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PIM1 MUTATED	1	0	3	4	0
PIM1 WILD-TYPE	5	11	4	8	5

'PIM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0365 (Fisher's exact test), Q value = 1

Table S400. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PIM1 MUTATED	6	1
PIM1 WILD-TYPE	11	18

Figure S15. Get High-res Image Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'PIM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S401. Gene #43: 'PIM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PIM1 MUTATED	1	0	2	3	1	0	0	0	0
PIM1 WILD-TYPE	3	5	3	3	6	1	4	1	3

'POTEE MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S402. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
POTEE MUTATED	4	3
POTEE WILD-TYPE	19	15

'POTEE MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S403. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
POTEE MUTATED	3	4
POTEE WILD-TYPE	17	17

'POTEE MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0421 (Fisher's exact test), Q value = 1

Table S404. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
POTEE MUTATED	5	0
POTEE WILD-TYPE	10	14

Figure S16. Get High-res Image Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'POTEE MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S405. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
POTEE MUTATED	1	4	0
POTEE WILD-TYPE	4	9	11

'POTEE MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S406. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
POTEE MUTATED	3	4
POTEE WILD-TYPE	6	8

'POTEE MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S407. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
POTEE MUTATED	4	3	0
POTEE WILD-TYPE	3	6	5

'POTEE MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0631 (Fisher's exact test), Q value = 1

Table S408. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
POTEE MUTATED	2	1	0	4
POTEE WILD-TYPE	9	10	10	5

'POTEE MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00183 (Fisher's exact test), Q value = 1

Table S409. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
POTEE MUTATED	3	1	0	0	3
POTEE WILD-TYPE	3	10	7	12	2

Figure S17. Get High-res Image Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'POTEE MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S410. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
POTEE MUTATED	3	4
POTEE WILD-TYPE	14	15

'POTEE MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0375 (Fisher's exact test), Q value = 1

Table S411. Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
POTEE MUTATED	1	0	0	0	3	1	1	1	0
POTEE WILD-TYPE	3	5	5	6	4	0	3	0	3

Figure S18. Get High-res Image Gene #44: 'POTEE MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'OR52E6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S412. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OR52E6 MUTATED	1	2
OR52E6 WILD-TYPE	22	16

'OR52E6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S413. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OR52E6 MUTATED	2	1
OR52E6 WILD-TYPE	18	20

'OR52E6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S414. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OR52E6 MUTATED	1	0
OR52E6 WILD-TYPE	14	14

'OR52E6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S415. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OR52E6 MUTATED	1	2
OR52E6 WILD-TYPE	8	10

'OR52E6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S416. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
OR52E6 MUTATED	0	2	1
OR52E6 WILD-TYPE	7	7	4

'OR52E6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S417. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OR52E6 MUTATED	1	1	0	1
OR52E6 WILD-TYPE	10	10	10	8

'OR52E6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S418. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OR52E6 MUTATED	0	1	1	0	1
OR52E6 WILD-TYPE	6	10	6	12	4

'OR52E6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S419. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OR52E6 MUTATED	1	2
OR52E6 WILD-TYPE	16	17

'OR52E6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S420. Gene #45: 'OR52E6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OR52E6 MUTATED	0	0	1	0	1	0	0	1	0
OR52E6 WILD-TYPE	4	5	4	6	6	1	4	0	3

'NBPF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S421. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
NBPF10 MUTATED	4	5
NBPF10 WILD-TYPE	19	13

'NBPF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S422. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
NBPF10 MUTATED	2	7
NBPF10 WILD-TYPE	18	14

'NBPF10 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S423. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
NBPF10 MUTATED	4	2
NBPF10 WILD-TYPE	11	12

'NBPF10 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S424. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
NBPF10 MUTATED	2	3	1
NBPF10 WILD-TYPE	3	10	10

'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S425. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
NBPF10 MUTATED	2	2
NBPF10 WILD-TYPE	7	10

'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S426. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
NBPF10 MUTATED	0	2	2
NBPF10 WILD-TYPE	7	7	3

'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S427. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
NBPF10 MUTATED	4	1	3	1
NBPF10 WILD-TYPE	7	10	7	8

'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S428. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
NBPF10 MUTATED	1	1	4	2	1
NBPF10 WILD-TYPE	5	10	3	10	4

'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S429. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
NBPF10 MUTATED	5	3
NBPF10 WILD-TYPE	12	16

'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.986 (Fisher's exact test), Q value = 1

Table S430. Gene #46: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
NBPF10 MUTATED	1	1	2	1	1	0	1	0	1
NBPF10 WILD-TYPE	3	4	3	5	6	1	3	1	2

'PRB2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S431. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PRB2 MUTATED	4	5
PRB2 WILD-TYPE	19	13

'PRB2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S432. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PRB2 MUTATED	4	5
PRB2 WILD-TYPE	16	16

'PRB2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S433. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PRB2 MUTATED	2	4
PRB2 WILD-TYPE	13	10

'PRB2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S434. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PRB2 MUTATED	0	3	3
PRB2 WILD-TYPE	5	10	8

'PRB2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S435. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PRB2 MUTATED	0	4
PRB2 WILD-TYPE	9	8

'PRB2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0541 (Fisher's exact test), Q value = 1

Table S436. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PRB2 MUTATED	0	4	0
PRB2 WILD-TYPE	7	5	5

'PRB2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S437. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PRB2 MUTATED	2	4	0	3
PRB2 WILD-TYPE	9	7	10	6

'PRB2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0234 (Fisher's exact test), Q value = 1

Table S438. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PRB2 MUTATED	0	5	2	0	2
PRB2 WILD-TYPE	6	6	5	12	3

Figure S19. Get High-res Image Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'PRB2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S439. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PRB2 MUTATED	2	5
PRB2 WILD-TYPE	15	14

'PRB2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S440. Gene #47: 'PRB2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PRB2 MUTATED	1	2	1	0	1	0	1	1	0
PRB2 WILD-TYPE	3	3	4	6	6	1	3	0	3

'MUC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S441. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
MUC6 MUTATED	13	8
MUC6 WILD-TYPE	10	10

'MUC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S442. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
MUC6 MUTATED	11	10
MUC6 WILD-TYPE	9	11

'MUC6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S443. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
MUC6 MUTATED	7	6
MUC6 WILD-TYPE	8	8

'MUC6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S444. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
MUC6 MUTATED	4	4	5
MUC6 WILD-TYPE	1	9	6

'MUC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S445. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
MUC6 MUTATED	4	8
MUC6 WILD-TYPE	5	4

'MUC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S446. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
MUC6 MUTATED	2	7	3
MUC6 WILD-TYPE	5	2	2

'MUC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S447. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
MUC6 MUTATED	7	6	4	4
MUC6 WILD-TYPE	4	5	6	5

'MUC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S448. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
MUC6 MUTATED	2	5	4	7	3
MUC6 WILD-TYPE	4	6	3	5	2

'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S449. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
MUC6 MUTATED	7	12
MUC6 WILD-TYPE	10	7

'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S450. Gene #48: 'MUC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
MUC6 MUTATED	2	3	2	2	4	0	3	1	2
MUC6 WILD-TYPE	2	2	3	4	3	1	1	0	1

'SALL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S451. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
SALL1 MUTATED	3	2
SALL1 WILD-TYPE	20	16

'SALL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S452. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
SALL1 MUTATED	3	2
SALL1 WILD-TYPE	17	19

'SALL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S453. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
SALL1 MUTATED	1	2
SALL1 WILD-TYPE	14	12

'SALL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S454. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
SALL1 MUTATED	0	2	1
SALL1 WILD-TYPE	5	11	10

'SALL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S455. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
SALL1 MUTATED	1	1
SALL1 WILD-TYPE	8	11

'SALL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S456. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
SALL1 MUTATED	1	2	1	1
SALL1 WILD-TYPE	10	9	9	8

'SALL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S457. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
SALL1 MUTATED	2	2	1	0	0
SALL1 WILD-TYPE	4	9	6	12	5

'SALL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S458. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
SALL1 MUTATED	2	2
SALL1 WILD-TYPE	15	17

'SALL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.325 (Fisher's exact test), Q value = 1

Table S459. Gene #49: 'SALL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
SALL1 MUTATED	0	0	0	1	1	0	1	1	0
SALL1 WILD-TYPE	4	5	5	5	6	1	3	0	3

'PAK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S460. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PAK2 MUTATED	6	1
PAK2 WILD-TYPE	17	17

'PAK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S461. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PAK2 MUTATED	3	4
PAK2 WILD-TYPE	17	17

'PAK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S462. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PAK2 MUTATED	3	1
PAK2 WILD-TYPE	12	13

'PAK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S463. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PAK2 MUTATED	1	2	1
PAK2 WILD-TYPE	4	11	10

'PAK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S464. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PAK2 MUTATED	2	3
PAK2 WILD-TYPE	7	9

'PAK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S465. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PAK2 MUTATED	1	2	2
PAK2 WILD-TYPE	6	7	3

'PAK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S466. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PAK2 MUTATED	2	2	0	3
PAK2 WILD-TYPE	9	9	10	6

'PAK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S467. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PAK2 MUTATED	0	1	1	3	2
PAK2 WILD-TYPE	6	10	6	9	3

'PAK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S468. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PAK2 MUTATED	1	5
PAK2 WILD-TYPE	16	14

'PAK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0866 (Fisher's exact test), Q value = 1

Table S469. Gene #50: 'PAK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PAK2 MUTATED	0	0	1	0	1	1	1	1	1
PAK2 WILD-TYPE	4	5	4	6	6	0	3	0	2

'FLG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S470. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FLG MUTATED	9	8
FLG WILD-TYPE	14	10

'FLG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S471. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FLG MUTATED	8	9
FLG WILD-TYPE	12	12

'FLG MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S472. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FLG MUTATED	7	5
FLG WILD-TYPE	8	9

'FLG MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S473. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
FLG MUTATED	2	5	5
FLG WILD-TYPE	3	8	6

'FLG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S474. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FLG MUTATED	4	5
FLG WILD-TYPE	5	7

'FLG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0494 (Fisher's exact test), Q value = 1

Table S475. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FLG MUTATED	5	4	0
FLG WILD-TYPE	2	5	5

Figure S20. Get High-res Image Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'FLG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S476. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FLG MUTATED	4	5	4	4
FLG WILD-TYPE	7	6	6	5

'FLG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S477. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FLG MUTATED	4	4	2	4	3
FLG WILD-TYPE	2	7	5	8	2

'FLG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S478. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FLG MUTATED	8	9
FLG WILD-TYPE	9	10

'FLG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0186 (Fisher's exact test), Q value = 1

Table S479. Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FLG MUTATED	3	2	0	3	6	0	0	1	2
FLG WILD-TYPE	1	3	5	3	1	1	4	0	1

Figure S21. Get High-res Image Gene #51: 'FLG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S480. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
MUC17 MUTATED	5	8
MUC17 WILD-TYPE	18	10

'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S481. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
MUC17 MUTATED	4	9
MUC17 WILD-TYPE	16	12

'MUC17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S482. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
MUC17 MUTATED	5	3
MUC17 WILD-TYPE	10	11

'MUC17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S483. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
MUC17 MUTATED	0	5	3
MUC17 WILD-TYPE	5	8	8

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S484. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
MUC17 MUTATED	3	5
MUC17 WILD-TYPE	6	7

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S485. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
MUC17 MUTATED	2	4	2
MUC17 WILD-TYPE	5	5	3

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S486. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
MUC17 MUTATED	5	2	3	3
MUC17 WILD-TYPE	6	9	7	6

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S487. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
MUC17 MUTATED	3	3	3	2	2
MUC17 WILD-TYPE	3	8	4	10	3

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S488. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
MUC17 MUTATED	7	5
MUC17 WILD-TYPE	10	14

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S489. Gene #52: 'MUC17 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
MUC17 MUTATED	1	1	2	3	4	0	0	1	0
MUC17 WILD-TYPE	3	4	3	3	3	1	4	0	3

'OR2T4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 1

Table S490. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OR2T4 MUTATED	7	1
OR2T4 WILD-TYPE	16	17

'OR2T4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S491. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OR2T4 MUTATED	6	2
OR2T4 WILD-TYPE	14	19

'OR2T4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S492. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OR2T4 MUTATED	2	3
OR2T4 WILD-TYPE	13	11

'OR2T4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S493. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
OR2T4 MUTATED	2	1	2
OR2T4 WILD-TYPE	3	12	9

'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S494. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OR2T4 MUTATED	0	4
OR2T4 WILD-TYPE	9	8

'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S495. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
OR2T4 MUTATED	0	3	1
OR2T4 WILD-TYPE	7	6	4

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0102 (Fisher's exact test), Q value = 1

Table S496. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OR2T4 MUTATED	1	6	1	0
OR2T4 WILD-TYPE	10	5	9	9

Figure S22. Get High-res Image Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.179 (Fisher's exact test), Q value = 1

Table S497. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OR2T4 MUTATED	1	5	1	1	0
OR2T4 WILD-TYPE	5	6	6	11	5

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S498. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OR2T4 MUTATED	2	6
OR2T4 WILD-TYPE	15	13

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00789 (Fisher's exact test), Q value = 1

Table S499. Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OR2T4 MUTATED	1	4	0	1	0	0	0	1	1
OR2T4 WILD-TYPE	3	1	5	5	7	1	4	0	2

Figure S23. Get High-res Image Gene #53: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'AMAC1L3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S500. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
AMAC1L3 MUTATED	3	2
AMAC1L3 WILD-TYPE	20	16

'AMAC1L3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S501. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
AMAC1L3 MUTATED	3	2
AMAC1L3 WILD-TYPE	17	19

'AMAC1L3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0996 (Fisher's exact test), Q value = 1

Table S502. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
AMAC1L3 MUTATED	4	0
AMAC1L3 WILD-TYPE	11	14

'AMAC1L3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 1

Table S503. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
AMAC1L3 MUTATED	1	3	0
AMAC1L3 WILD-TYPE	4	10	11

'AMAC1L3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S504. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
AMAC1L3 MUTATED	3	2
AMAC1L3 WILD-TYPE	6	10

'AMAC1L3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S505. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
AMAC1L3 MUTATED	3	2	0
AMAC1L3 WILD-TYPE	4	7	5

'AMAC1L3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S506. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
AMAC1L3 MUTATED	3	1	0	1
AMAC1L3 WILD-TYPE	8	10	10	8

'AMAC1L3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0189 (Fisher's exact test), Q value = 1

Table S507. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
AMAC1L3 MUTATED	3	1	0	0	1
AMAC1L3 WILD-TYPE	3	10	7	12	4

Figure S24. Get High-res Image Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'AMAC1L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S508. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
AMAC1L3 MUTATED	3	2
AMAC1L3 WILD-TYPE	14	17

'AMAC1L3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0654 (Fisher's exact test), Q value = 1

Table S509. Gene #54: 'AMAC1L3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
AMAC1L3 MUTATED	1	0	0	0	3	0	0	1	0
AMAC1L3 WILD-TYPE	3	5	5	6	4	1	4	0	3

'APOB MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S510. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
APOB MUTATED	2	1
APOB WILD-TYPE	21	17

'APOB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 1

Table S511. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
APOB MUTATED	3	0
APOB WILD-TYPE	17	21

'APOB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S512. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
APOB MUTATED	1	0
APOB WILD-TYPE	14	14

'APOB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S513. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
APOB MUTATED	0	2
APOB WILD-TYPE	9	10

'APOB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S514. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
APOB MUTATED	0	1	0	2
APOB WILD-TYPE	11	10	10	7

'APOB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S515. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
APOB MUTATED	0	1	0	1	1
APOB WILD-TYPE	6	10	7	11	4

'APOB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S516. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
APOB MUTATED	0	3
APOB WILD-TYPE	17	16

'APOB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S517. Gene #55: 'APOB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
APOB MUTATED	0	0	1	0	1	0	0	1	0
APOB WILD-TYPE	4	5	4	6	6	1	4	0	3

'KRTAP4-7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0594 (Fisher's exact test), Q value = 1

Table S518. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KRTAP4-7 MUTATED	7	1
KRTAP4-7 WILD-TYPE	16	17

'KRTAP4-7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S519. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KRTAP4-7 MUTATED	4	4
KRTAP4-7 WILD-TYPE	16	17

'KRTAP4-7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S520. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KRTAP4-7 MUTATED	3	4
KRTAP4-7 WILD-TYPE	12	10

'KRTAP4-7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S521. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
KRTAP4-7 MUTATED	0	3	4
KRTAP4-7 WILD-TYPE	5	10	7

'KRTAP4-7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0451 (Fisher's exact test), Q value = 1

Table S522. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KRTAP4-7 MUTATED	0	5
KRTAP4-7 WILD-TYPE	9	7

Figure S25. Get High-res Image Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'KRTAP4-7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S523. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KRTAP4-7 MUTATED	2	3	0
KRTAP4-7 WILD-TYPE	5	6	5

'KRTAP4-7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S524. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KRTAP4-7 MUTATED	1	3	2	2
KRTAP4-7 WILD-TYPE	10	8	8	7

'KRTAP4-7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S525. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KRTAP4-7 MUTATED	2	3	0	1	2
KRTAP4-7 WILD-TYPE	4	8	7	11	3

'KRTAP4-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S526. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KRTAP4-7 MUTATED	2	6
KRTAP4-7 WILD-TYPE	15	13

'KRTAP4-7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.271 (Fisher's exact test), Q value = 1

Table S527. Gene #56: 'KRTAP4-7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KRTAP4-7 MUTATED	1	1	0	2	2	1	0	1	0
KRTAP4-7 WILD-TYPE	3	4	5	4	5	0	4	0	3

'MUC16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S528. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
MUC16 MUTATED	9	4
MUC16 WILD-TYPE	14	14

'MUC16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S529. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
MUC16 MUTATED	4	9
MUC16 WILD-TYPE	16	12

'MUC16 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S530. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
MUC16 MUTATED	6	3
MUC16 WILD-TYPE	9	11

'MUC16 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S531. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
MUC16 MUTATED	0	6	3
MUC16 WILD-TYPE	5	7	8

'MUC16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S532. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
MUC16 MUTATED	4	4
MUC16 WILD-TYPE	5	8

'MUC16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S533. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
MUC16 MUTATED	3	3	2
MUC16 WILD-TYPE	4	6	3

'MUC16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S534. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
MUC16 MUTATED	3	3	3	4
MUC16 WILD-TYPE	8	8	7	5

'MUC16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S535. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
MUC16 MUTATED	1	3	2	4	3
MUC16 WILD-TYPE	5	8	5	8	2

'MUC16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S536. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
MUC16 MUTATED	4	7
MUC16 WILD-TYPE	13	12

'MUC16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S537. Gene #57: 'MUC16 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
MUC16 MUTATED	1	2	1	2	3	1	0	1	0
MUC16 WILD-TYPE	3	3	4	4	4	0	4	0	3

'NEFH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S538. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
NEFH MUTATED	5	1
NEFH WILD-TYPE	18	17

'NEFH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S539. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
NEFH MUTATED	2	4
NEFH WILD-TYPE	18	17

'NEFH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0421 (Fisher's exact test), Q value = 1

Table S540. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
NEFH MUTATED	5	0
NEFH WILD-TYPE	10	14

Figure S26. Get High-res Image Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

'NEFH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.091 (Fisher's exact test), Q value = 1

Table S541. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
NEFH MUTATED	2	3	0
NEFH WILD-TYPE	3	10	11

'NEFH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S542. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
NEFH MUTATED	1	2
NEFH WILD-TYPE	8	10

'NEFH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S543. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
NEFH MUTATED	2	0	1
NEFH WILD-TYPE	5	9	4

'NEFH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S544. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
NEFH MUTATED	2	1	2	1
NEFH WILD-TYPE	9	10	8	8

'NEFH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S545. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
NEFH MUTATED	2	1	1	1	1
NEFH WILD-TYPE	4	10	6	11	4

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S546. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
NEFH MUTATED	4	2
NEFH WILD-TYPE	13	17

'NEFH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0921 (Fisher's exact test), Q value = 1

Table S547. Gene #58: 'NEFH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
NEFH MUTATED	2	1	0	2	0	1	0	0	0
NEFH WILD-TYPE	2	4	5	4	7	0	4	1	3

'KCNN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 1

Table S548. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KCNN3 MUTATED	2	5
KCNN3 WILD-TYPE	21	13

'KCNN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S549. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KCNN3 MUTATED	3	4
KCNN3 WILD-TYPE	17	17

'KCNN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S550. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KCNN3 MUTATED	2	5
KCNN3 WILD-TYPE	13	9

'KCNN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S551. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
KCNN3 MUTATED	1	2	4
KCNN3 WILD-TYPE	4	11	7

'KCNN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S552. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KCNN3 MUTATED	2	3
KCNN3 WILD-TYPE	7	9

'KCNN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S553. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KCNN3 MUTATED	1	3	1
KCNN3 WILD-TYPE	6	6	4

'KCNN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S554. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KCNN3 MUTATED	2	2	1	2
KCNN3 WILD-TYPE	9	9	9	7

'KCNN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S555. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KCNN3 MUTATED	0	2	2	1	2
KCNN3 WILD-TYPE	6	9	5	11	3

'KCNN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S556. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KCNN3 MUTATED	3	3
KCNN3 WILD-TYPE	14	16

'KCNN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S557. Gene #59: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KCNN3 MUTATED	0	1	2	0	3	0	0	0	0
KCNN3 WILD-TYPE	4	4	3	6	4	1	4	1	3

'RNASEH2B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S558. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
RNASEH2B MUTATED	1	2
RNASEH2B WILD-TYPE	22	16

'RNASEH2B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S559. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
RNASEH2B MUTATED	2	1
RNASEH2B WILD-TYPE	18	20

'RNASEH2B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S560. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
RNASEH2B MUTATED	1	1
RNASEH2B WILD-TYPE	14	13

'RNASEH2B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0185 (Fisher's exact test), Q value = 1

Table S561. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
RNASEH2B MUTATED	0	0	3	0
RNASEH2B WILD-TYPE	11	11	7	9

Figure S27. Get High-res Image Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'RNASEH2B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S562. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
RNASEH2B MUTATED	1	0	0	2	0
RNASEH2B WILD-TYPE	5	11	7	10	5

'RNASEH2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S563. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
RNASEH2B MUTATED	2	1
RNASEH2B WILD-TYPE	15	18

'RNASEH2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S564. Gene #60: 'RNASEH2B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
RNASEH2B MUTATED	0	0	0	2	0	0	0	0	1
RNASEH2B WILD-TYPE	4	5	5	4	7	1	4	1	2

'FAM153B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S565. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FAM153B MUTATED	2	1
FAM153B WILD-TYPE	21	17

'FAM153B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S566. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FAM153B MUTATED	1	2
FAM153B WILD-TYPE	19	19

'FAM153B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S567. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FAM153B MUTATED	2	1
FAM153B WILD-TYPE	13	13

'FAM153B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.374 (Fisher's exact test), Q value = 1

Table S568. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
FAM153B MUTATED	1	2	0
FAM153B WILD-TYPE	4	11	11

'FAM153B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S569. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FAM153B MUTATED	0	1
FAM153B WILD-TYPE	9	11

'FAM153B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S570. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FAM153B MUTATED	1	1	1	0
FAM153B WILD-TYPE	10	10	9	9

'FAM153B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S571. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FAM153B MUTATED	0	1	1	1	0
FAM153B WILD-TYPE	6	10	6	11	5

'FAM153B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S572. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FAM153B MUTATED	2	1
FAM153B WILD-TYPE	15	18

'FAM153B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S573. Gene #61: 'FAM153B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FAM153B MUTATED	1	1	0	1	0	0	0	0	0
FAM153B WILD-TYPE	3	4	5	5	7	1	4	1	3

'OTOP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S574. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OTOP1 MUTATED	1	3
OTOP1 WILD-TYPE	22	15

'OTOP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S575. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OTOP1 MUTATED	2	2
OTOP1 WILD-TYPE	18	19

'OTOP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S576. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OTOP1 MUTATED	1	2
OTOP1 WILD-TYPE	14	12

'OTOP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S577. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
OTOP1 MUTATED	0	1	2
OTOP1 WILD-TYPE	5	12	9

'OTOP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S578. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OTOP1 MUTATED	1	2
OTOP1 WILD-TYPE	8	10

'OTOP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S579. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
OTOP1 MUTATED	1	2	0
OTOP1 WILD-TYPE	6	7	5

'OTOP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 1

Table S580. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OTOP1 MUTATED	2	2	0	0
OTOP1 WILD-TYPE	9	9	10	9

'OTOP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S581. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OTOP1 MUTATED	1	2	1	0	0
OTOP1 WILD-TYPE	5	9	6	12	5

'OTOP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S582. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OTOP1 MUTATED	2	2
OTOP1 WILD-TYPE	15	17

'OTOP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S583. Gene #62: 'OTOP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OTOP1 MUTATED	0	1	0	0	2	0	1	0	0
OTOP1 WILD-TYPE	4	4	5	6	5	1	3	1	3

'AATK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S584. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
AATK MUTATED	1	2
AATK WILD-TYPE	22	16

'AATK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S585. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
AATK MUTATED	1	2
AATK WILD-TYPE	19	19

'AATK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S586. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
AATK MUTATED	2	0
AATK WILD-TYPE	13	14

'AATK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S587. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
AATK MUTATED	1	2
AATK WILD-TYPE	8	10

'AATK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S588. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
AATK MUTATED	0	2	1
AATK WILD-TYPE	7	7	4

'AATK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S589. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
AATK MUTATED	1	1	0	1
AATK WILD-TYPE	10	10	10	8

'AATK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S590. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
AATK MUTATED	0	1	1	0	1
AATK WILD-TYPE	6	10	6	12	4

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S591. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
AATK MUTATED	1	2
AATK WILD-TYPE	16	17

'AATK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0876 (Fisher's exact test), Q value = 1

Table S592. Gene #63: 'AATK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
AATK MUTATED	0	0	1	0	0	0	1	1	0
AATK WILD-TYPE	4	5	4	6	7	1	3	0	3

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S593. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ARID1A MUTATED	3	2
ARID1A WILD-TYPE	20	16

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S594. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ARID1A MUTATED	3	2
ARID1A WILD-TYPE	17	19

'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S595. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ARID1A MUTATED	1	1
ARID1A WILD-TYPE	14	13

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S596. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ARID1A MUTATED	2	2
ARID1A WILD-TYPE	7	10

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S597. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ARID1A MUTATED	0	2	2
ARID1A WILD-TYPE	7	7	3

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S598. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ARID1A MUTATED	1	2	0	2
ARID1A WILD-TYPE	10	9	10	7

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S599. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ARID1A MUTATED	1	2	0	1	1
ARID1A WILD-TYPE	5	9	7	11	4

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S600. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ARID1A MUTATED	0	4
ARID1A WILD-TYPE	17	15

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0286 (Fisher's exact test), Q value = 1

Table S601. Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ARID1A MUTATED	0	1	0	0	0	0	2	1	0
ARID1A WILD-TYPE	4	4	5	6	7	1	2	0	3

Figure S28. Get High-res Image Gene #64: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GUCA1C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S602. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
GUCA1C MUTATED	1	2
GUCA1C WILD-TYPE	22	16

'GUCA1C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S603. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
GUCA1C MUTATED	2	1
GUCA1C WILD-TYPE	18	20

'GUCA1C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S604. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
GUCA1C MUTATED	1	0
GUCA1C WILD-TYPE	14	14

'GUCA1C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S605. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
GUCA1C MUTATED	1	2
GUCA1C WILD-TYPE	8	10

'GUCA1C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S606. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
GUCA1C MUTATED	0	2	1
GUCA1C WILD-TYPE	7	7	4

'GUCA1C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S607. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
GUCA1C MUTATED	1	1	0	1
GUCA1C WILD-TYPE	10	10	10	8

'GUCA1C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S608. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
GUCA1C MUTATED	0	1	1	0	1
GUCA1C WILD-TYPE	6	10	6	12	4

'GUCA1C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S609. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
GUCA1C MUTATED	1	2
GUCA1C WILD-TYPE	16	17

'GUCA1C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 1

Table S610. Gene #65: 'GUCA1C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
GUCA1C MUTATED	0	0	1	0	1	0	0	1	0
GUCA1C WILD-TYPE	4	5	4	6	6	1	4	0	3

'TRIM48 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S611. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TRIM48 MUTATED	5	3
TRIM48 WILD-TYPE	18	15

'TRIM48 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S612. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TRIM48 MUTATED	4	4
TRIM48 WILD-TYPE	16	17

'TRIM48 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S613. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TRIM48 MUTATED	3	4
TRIM48 WILD-TYPE	12	10

'TRIM48 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S614. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TRIM48 MUTATED	0	3	4
TRIM48 WILD-TYPE	5	10	7

'TRIM48 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S615. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TRIM48 MUTATED	0	3
TRIM48 WILD-TYPE	9	9

'TRIM48 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S616. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
TRIM48 MUTATED	0	3	0
TRIM48 WILD-TYPE	7	6	5

'TRIM48 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S617. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TRIM48 MUTATED	2	2	3	1
TRIM48 WILD-TYPE	9	9	7	8

'TRIM48 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S618. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TRIM48 MUTATED	1	2	1	3	1
TRIM48 WILD-TYPE	5	9	6	9	4

'TRIM48 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S619. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TRIM48 MUTATED	4	4
TRIM48 WILD-TYPE	13	15

'TRIM48 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S620. Gene #66: 'TRIM48 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TRIM48 MUTATED	0	1	0	3	2	0	1	1	0
TRIM48 WILD-TYPE	4	4	5	3	5	1	3	0	3

'CSGALNACT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S621. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CSGALNACT2 MUTATED	3	2
CSGALNACT2 WILD-TYPE	20	16

'CSGALNACT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S622. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CSGALNACT2 MUTATED	2	3
CSGALNACT2 WILD-TYPE	18	18

'CSGALNACT2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S623. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CSGALNACT2 MUTATED	3	0
CSGALNACT2 WILD-TYPE	12	14

'CSGALNACT2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S624. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
CSGALNACT2 MUTATED	0	3	0
CSGALNACT2 WILD-TYPE	5	10	11

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S625. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CSGALNACT2 MUTATED	2	3
CSGALNACT2 WILD-TYPE	7	9

'CSGALNACT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S626. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CSGALNACT2 MUTATED	2	1	2
CSGALNACT2 WILD-TYPE	5	8	3

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S627. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CSGALNACT2 MUTATED	1	2	0	2
CSGALNACT2 WILD-TYPE	10	9	10	7

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S628. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CSGALNACT2 MUTATED	0	2	1	0	2
CSGALNACT2 WILD-TYPE	6	9	6	12	3

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S629. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CSGALNACT2 MUTATED	1	4
CSGALNACT2 WILD-TYPE	16	15

'CSGALNACT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0835 (Fisher's exact test), Q value = 1

Table S630. Gene #67: 'CSGALNACT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CSGALNACT2 MUTATED	0	1	1	0	1	1	0	1	0
CSGALNACT2 WILD-TYPE	4	4	4	6	6	0	4	0	3

'CRIPAK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S631. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CRIPAK MUTATED	4	2
CRIPAK WILD-TYPE	19	16

'CRIPAK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00862 (Fisher's exact test), Q value = 1

Table S632. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CRIPAK MUTATED	6	0
CRIPAK WILD-TYPE	14	21

Figure S29. Get High-res Image Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CRIPAK MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S633. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CRIPAK MUTATED	0	2
CRIPAK WILD-TYPE	15	12

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 1

Table S634. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CRIPAK MUTATED	1	5
CRIPAK WILD-TYPE	8	7

'CRIPAK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S635. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CRIPAK MUTATED	1	3	2
CRIPAK WILD-TYPE	6	6	3

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0272 (Fisher's exact test), Q value = 1

Table S636. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CRIPAK MUTATED	0	4	0	2
CRIPAK WILD-TYPE	11	7	10	7

Figure S30. Get High-res Image Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0726 (Fisher's exact test), Q value = 1

Table S637. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CRIPAK MUTATED	1	4	0	0	1
CRIPAK WILD-TYPE	5	7	7	12	4

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0203 (Fisher's exact test), Q value = 1

Table S638. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CRIPAK MUTATED	0	6
CRIPAK WILD-TYPE	17	13

Figure S31. Get High-res Image Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'CRIPAK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.257 (Fisher's exact test), Q value = 1

Table S639. Gene #68: 'CRIPAK MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CRIPAK MUTATED	1	2	0	0	1	0	1	1	0
CRIPAK WILD-TYPE	3	3	5	6	6	1	3	0	3

'DHRS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S640. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
DHRS4 MUTATED	2	2
DHRS4 WILD-TYPE	21	16

'DHRS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0478 (Fisher's exact test), Q value = 1

Table S641. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
DHRS4 MUTATED	4	0
DHRS4 WILD-TYPE	16	21

Figure S32. Get High-res Image Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'DHRS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S642. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
DHRS4 MUTATED	0	2
DHRS4 WILD-TYPE	15	12

'DHRS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 1

Table S643. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
DHRS4 MUTATED	0	4
DHRS4 WILD-TYPE	9	8

'DHRS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0555 (Fisher's exact test), Q value = 1

Table S644. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
DHRS4 MUTATED	0	4	0
DHRS4 WILD-TYPE	7	5	5

'DHRS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S645. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
DHRS4 MUTATED	0	3	0	1
DHRS4 WILD-TYPE	11	8	10	8

'DHRS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 1

Table S646. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
DHRS4 MUTATED	0	3	0	0	1
DHRS4 WILD-TYPE	6	8	7	12	4

'DHRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S647. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
DHRS4 MUTATED	0	3
DHRS4 WILD-TYPE	17	16

'DHRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.212 (Fisher's exact test), Q value = 1

Table S648. Gene #69: 'DHRS4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
DHRS4 MUTATED	0	1	0	0	1	0	0	1	0
DHRS4 WILD-TYPE	4	4	5	6	6	1	4	0	3

'FAM21A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S649. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FAM21A MUTATED	3	1
FAM21A WILD-TYPE	20	17

'FAM21A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S650. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FAM21A MUTATED	3	1
FAM21A WILD-TYPE	17	20

'FAM21A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S651. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FAM21A MUTATED	0	1
FAM21A WILD-TYPE	15	13

'FAM21A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S652. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FAM21A MUTATED	0	3
FAM21A WILD-TYPE	9	9

'FAM21A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S653. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FAM21A MUTATED	0	2	1
FAM21A WILD-TYPE	7	7	4

'FAM21A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S654. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FAM21A MUTATED	0	2	1	1
FAM21A WILD-TYPE	11	9	9	8

'FAM21A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.611 (Fisher's exact test), Q value = 1

Table S655. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FAM21A MUTATED	0	2	0	1	1
FAM21A WILD-TYPE	6	9	7	11	4

'FAM21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S656. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FAM21A MUTATED	0	4
FAM21A WILD-TYPE	17	15

'FAM21A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S657. Gene #70: 'FAM21A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FAM21A MUTATED	0	1	0	1	1	0	0	1	0
FAM21A WILD-TYPE	4	4	5	5	6	1	4	0	3

'KIAA1529 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S658. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KIAA1529 MUTATED	3	1
KIAA1529 WILD-TYPE	20	17

'KIAA1529 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S659. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KIAA1529 MUTATED	2	2
KIAA1529 WILD-TYPE	18	19

'KIAA1529 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S660. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KIAA1529 MUTATED	1	0
KIAA1529 WILD-TYPE	14	14

'KIAA1529 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S661. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KIAA1529 MUTATED	1	2
KIAA1529 WILD-TYPE	8	10

'KIAA1529 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S662. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KIAA1529 MUTATED	0	2	1
KIAA1529 WILD-TYPE	7	7	4

'KIAA1529 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S663. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KIAA1529 MUTATED	1	1	1	1
KIAA1529 WILD-TYPE	10	10	9	8

'KIAA1529 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S664. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KIAA1529 MUTATED	1	1	0	1	1
KIAA1529 WILD-TYPE	5	10	7	11	4

'KIAA1529 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S665. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KIAA1529 MUTATED	1	2
KIAA1529 WILD-TYPE	16	17

'KIAA1529 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S666. Gene #71: 'KIAA1529 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KIAA1529 MUTATED	0	0	0	1	1	0	0	1	0
KIAA1529 WILD-TYPE	4	5	5	5	6	1	4	0	3

'OR2M5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S667. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OR2M5 MUTATED	3	1
OR2M5 WILD-TYPE	20	17

'OR2M5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S668. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OR2M5 MUTATED	1	3
OR2M5 WILD-TYPE	19	18

'OR2M5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S669. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OR2M5 MUTATED	3	0
OR2M5 WILD-TYPE	12	14

'OR2M5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0665 (Fisher's exact test), Q value = 1

Table S670. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
OR2M5 MUTATED	2	1	0
OR2M5 WILD-TYPE	3	12	11

'OR2M5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0632 (Fisher's exact test), Q value = 1

Table S671. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OR2M5 MUTATED	3	0
OR2M5 WILD-TYPE	6	12

'OR2M5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S672. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
OR2M5 MUTATED	2	0	1
OR2M5 WILD-TYPE	5	9	4

'OR2M5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S673. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OR2M5 MUTATED	3	0	0	1
OR2M5 WILD-TYPE	8	11	10	8

'OR2M5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S674. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OR2M5 MUTATED	2	0	1	1	0
OR2M5 WILD-TYPE	4	11	6	11	5

'OR2M5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0952 (Fisher's exact test), Q value = 1

Table S675. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OR2M5 MUTATED	3	0
OR2M5 WILD-TYPE	14	19

'OR2M5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 1

Table S676. Gene #72: 'OR2M5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OR2M5 MUTATED	2	0	0	0	1	0	0	0	0
OR2M5 WILD-TYPE	2	5	5	6	6	1	4	1	3

'KRT6A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S677. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KRT6A MUTATED	1	3
KRT6A WILD-TYPE	22	15

'KRT6A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S678. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KRT6A MUTATED	1	3
KRT6A WILD-TYPE	19	18

'KRT6A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S679. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KRT6A MUTATED	2	2
KRT6A WILD-TYPE	13	12

'KRT6A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S680. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
KRT6A MUTATED	0	2	2
KRT6A WILD-TYPE	5	11	9

'KRT6A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S681. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KRT6A MUTATED	1	2
KRT6A WILD-TYPE	8	10

'KRT6A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S682. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KRT6A MUTATED	0	2	1
KRT6A WILD-TYPE	7	7	4

'KRT6A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S683. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KRT6A MUTATED	1	1	1	1
KRT6A WILD-TYPE	10	10	9	8

'KRT6A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S684. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KRT6A MUTATED	0	1	1	1	1
KRT6A WILD-TYPE	6	10	6	11	4

'KRT6A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S685. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KRT6A MUTATED	2	1
KRT6A WILD-TYPE	15	18

'KRT6A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S686. Gene #73: 'KRT6A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KRT6A MUTATED	0	0	1	1	1	0	0	0	0
KRT6A WILD-TYPE	4	5	4	5	6	1	4	1	3

'CYP2F1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S687. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CYP2F1 MUTATED	2	2
CYP2F1 WILD-TYPE	21	16

'CYP2F1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S688. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CYP2F1 MUTATED	3	1
CYP2F1 WILD-TYPE	17	20

'CYP2F1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 1

Table S689. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CYP2F1 MUTATED	0	2
CYP2F1 WILD-TYPE	15	12

'CYP2F1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S690. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CYP2F1 MUTATED	0	3
CYP2F1 WILD-TYPE	9	9

'CYP2F1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S691. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
CYP2F1 MUTATED	0	3	0
CYP2F1 WILD-TYPE	7	6	5

'CYP2F1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 1

Table S692. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CYP2F1 MUTATED	0	2	0	2
CYP2F1 WILD-TYPE	11	9	10	7

'CYP2F1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0527 (Fisher's exact test), Q value = 1

Table S693. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CYP2F1 MUTATED	0	2	0	0	2
CYP2F1 WILD-TYPE	6	9	7	12	3

'CYP2F1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S694. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CYP2F1 MUTATED	0	4
CYP2F1 WILD-TYPE	17	15

'CYP2F1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S695. Gene #74: 'CYP2F1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CYP2F1 MUTATED	0	1	0	0	2	0	0	1	0
CYP2F1 WILD-TYPE	4	4	5	6	5	1	4	0	3

'FCGBP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S696. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FCGBP MUTATED	2	3
FCGBP WILD-TYPE	21	15

'FCGBP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S697. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FCGBP MUTATED	4	1
FCGBP WILD-TYPE	16	20

'FCGBP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S698. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FCGBP MUTATED	1	1
FCGBP WILD-TYPE	14	13

'FCGBP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S699. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FCGBP MUTATED	1	3
FCGBP WILD-TYPE	8	9

'FCGBP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.23 (Fisher's exact test), Q value = 1

Table S700. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FCGBP MUTATED	0	2	2
FCGBP WILD-TYPE	7	7	3

'FCGBP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S701. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FCGBP MUTATED	1	2	1	1
FCGBP WILD-TYPE	10	9	9	8

'FCGBP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S702. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FCGBP MUTATED	0	2	1	1	1
FCGBP WILD-TYPE	6	9	6	11	4

'FCGBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S703. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FCGBP MUTATED	2	3
FCGBP WILD-TYPE	15	16

'FCGBP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S704. Gene #75: 'FCGBP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FCGBP MUTATED	0	1	1	1	1	0	0	1	0
FCGBP WILD-TYPE	4	4	4	5	6	1	4	0	3

'ZNF493 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S705. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ZNF493 MUTATED	3	1
ZNF493 WILD-TYPE	20	17

'ZNF493 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S706. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ZNF493 MUTATED	2	2
ZNF493 WILD-TYPE	18	19

'ZNF493 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S707. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ZNF493 MUTATED	1	0
ZNF493 WILD-TYPE	14	14

'ZNF493 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S708. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ZNF493 MUTATED	1	2
ZNF493 WILD-TYPE	8	10

'ZNF493 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S709. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ZNF493 MUTATED	0	2	1
ZNF493 WILD-TYPE	7	7	4

'ZNF493 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S710. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ZNF493 MUTATED	1	1	1	1
ZNF493 WILD-TYPE	10	10	9	8

'ZNF493 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S711. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ZNF493 MUTATED	0	1	0	2	1
ZNF493 WILD-TYPE	6	10	7	10	4

'ZNF493 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S712. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ZNF493 MUTATED	1	2
ZNF493 WILD-TYPE	16	17

'ZNF493 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.27 (Fisher's exact test), Q value = 1

Table S713. Gene #76: 'ZNF493 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ZNF493 MUTATED	0	0	0	1	1	0	0	1	0
ZNF493 WILD-TYPE	4	5	5	5	6	1	4	0	3

'HLA-B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S714. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
HLA-B MUTATED	5	2
HLA-B WILD-TYPE	18	16

'HLA-B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S715. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
HLA-B MUTATED	4	3
HLA-B WILD-TYPE	16	18

'HLA-B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S716. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
HLA-B MUTATED	4	1
HLA-B WILD-TYPE	11	13

'HLA-B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S717. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
HLA-B MUTATED	1	4	0
HLA-B WILD-TYPE	4	9	11

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S718. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
HLA-B MUTATED	1	3
HLA-B WILD-TYPE	8	9

'HLA-B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S719. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
HLA-B MUTATED	2	2	0
HLA-B WILD-TYPE	5	7	5

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S720. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
HLA-B MUTATED	2	2	1	2
HLA-B WILD-TYPE	9	9	9	7

'HLA-B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S721. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
HLA-B MUTATED	1	2	1	1	2
HLA-B WILD-TYPE	5	9	6	11	3

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S722. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
HLA-B MUTATED	3	3
HLA-B WILD-TYPE	14	16

'HLA-B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0396 (Fisher's exact test), Q value = 1

Table S723. Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
HLA-B MUTATED	2	0	0	1	1	1	0	1	0
HLA-B WILD-TYPE	2	5	5	5	6	0	4	0	3

Figure S33. Get High-res Image Gene #77: 'HLA-B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FCRLA MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S724. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FCRLA MUTATED	2	1
FCRLA WILD-TYPE	21	17

'FCRLA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S725. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FCRLA MUTATED	2	1
FCRLA WILD-TYPE	18	20

'FCRLA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S726. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FCRLA MUTATED	1	2
FCRLA WILD-TYPE	8	10

'FCRLA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S727. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
FCRLA MUTATED	0	2	1
FCRLA WILD-TYPE	7	7	4

'FCRLA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S728. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FCRLA MUTATED	1	1	0	1
FCRLA WILD-TYPE	10	10	10	8

'FCRLA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S729. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FCRLA MUTATED	0	1	0	1	1
FCRLA WILD-TYPE	6	10	7	11	4

'FCRLA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S730. Gene #78: 'FCRLA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FCRLA MUTATED	0	2
FCRLA WILD-TYPE	17	17

'KLRC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S731. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KLRC2 MUTATED	3	2
KLRC2 WILD-TYPE	20	16

'KLRC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S732. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KLRC2 MUTATED	3	2
KLRC2 WILD-TYPE	17	19

'KLRC2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S733. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KLRC2 MUTATED	1	2
KLRC2 WILD-TYPE	14	12

'KLRC2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S734. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
KLRC2 MUTATED	1	1	1
KLRC2 WILD-TYPE	4	12	10

'KLRC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S735. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KLRC2 MUTATED	1	4
KLRC2 WILD-TYPE	8	8

'KLRC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.815 (Fisher's exact test), Q value = 1

Table S736. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KLRC2 MUTATED	1	3	1
KLRC2 WILD-TYPE	6	6	4

'KLRC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S737. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KLRC2 MUTATED	1	2	0	2
KLRC2 WILD-TYPE	10	9	10	7

'KLRC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 1

Table S738. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KLRC2 MUTATED	0	2	0	1	2
KLRC2 WILD-TYPE	6	9	7	11	3

'KLRC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S739. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KLRC2 MUTATED	0	4
KLRC2 WILD-TYPE	17	15

'KLRC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S740. Gene #79: 'KLRC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KLRC2 MUTATED	1	1	0	0	1	0	1	0	0
KLRC2 WILD-TYPE	3	4	5	6	6	1	3	1	3

'CD79B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S741. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
CD79B MUTATED	2	3
CD79B WILD-TYPE	21	15

'CD79B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S742. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
CD79B MUTATED	1	4
CD79B WILD-TYPE	19	17

'CD79B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0996 (Fisher's exact test), Q value = 1

Table S743. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
CD79B MUTATED	0	3
CD79B WILD-TYPE	15	11

'CD79B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S744. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
CD79B MUTATED	0	0	3
CD79B WILD-TYPE	5	13	8

'CD79B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S745. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
CD79B MUTATED	1	1
CD79B WILD-TYPE	8	11

'CD79B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S746. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
CD79B MUTATED	2	1	2	0
CD79B WILD-TYPE	9	10	8	9

'CD79B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S747. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
CD79B MUTATED	0	1	2	2	0
CD79B WILD-TYPE	6	10	5	10	5

'CD79B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S748. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
CD79B MUTATED	2	1
CD79B WILD-TYPE	15	18

'CD79B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S749. Gene #80: 'CD79B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
CD79B MUTATED	0	0	2	1	0	0	0	0	0
CD79B WILD-TYPE	4	5	3	5	7	1	4	1	3

'TMSB4X MUTATION STATUS' versus 'CN_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S750. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
TMSB4X MUTATED	4	1
TMSB4X WILD-TYPE	19	17

'TMSB4X MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 1

Table S751. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
TMSB4X MUTATED	4	1
TMSB4X WILD-TYPE	16	20

'TMSB4X MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S752. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
TMSB4X MUTATED	2	3
TMSB4X WILD-TYPE	13	11

'TMSB4X MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S753. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
TMSB4X MUTATED	0	2	3
TMSB4X WILD-TYPE	5	11	8

'TMSB4X MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S754. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
TMSB4X MUTATED	1	2
TMSB4X WILD-TYPE	8	10

'TMSB4X MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S755. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
TMSB4X MUTATED	2	1	0
TMSB4X WILD-TYPE	5	8	5

'TMSB4X MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S756. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
TMSB4X MUTATED	1	3	0	1
TMSB4X WILD-TYPE	10	8	10	8

'TMSB4X MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S757. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
TMSB4X MUTATED	1	3	0	1	0
TMSB4X WILD-TYPE	5	8	7	11	5

'TMSB4X MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S758. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
TMSB4X MUTATED	1	4
TMSB4X WILD-TYPE	16	15

'TMSB4X MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S759. Gene #81: 'TMSB4X MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
TMSB4X MUTATED	1	2	1	0	1	0	0	0	0
TMSB4X WILD-TYPE	3	3	4	6	6	1	4	1	3

'PRB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S760. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PRB1 MUTATED	4	1
PRB1 WILD-TYPE	19	17

'PRB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0207 (Fisher's exact test), Q value = 1

Table S761. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PRB1 MUTATED	5	0
PRB1 WILD-TYPE	15	21

Figure S34. Get High-res Image Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'PRB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S762. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PRB1 MUTATED	1	1
PRB1 WILD-TYPE	14	13

'PRB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 1

Table S763. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PRB1 MUTATED	0	3
PRB1 WILD-TYPE	9	9

'PRB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S764. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PRB1 MUTATED	0	3	0
PRB1 WILD-TYPE	7	6	5

'PRB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0811 (Fisher's exact test), Q value = 1

Table S765. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PRB1 MUTATED	0	3	0	2
PRB1 WILD-TYPE	11	8	10	7

'PRB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S766. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PRB1 MUTATED	0	2	0	2	1
PRB1 WILD-TYPE	6	9	7	10	4

'PRB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0473 (Fisher's exact test), Q value = 1

Table S767. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PRB1 MUTATED	0	5
PRB1 WILD-TYPE	17	14

Figure S35. Get High-res Image Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'PRB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S768. Gene #82: 'PRB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PRB1 MUTATED	0	1	1	0	1	0	0	1	1
PRB1 WILD-TYPE	4	4	4	6	6	1	4	0	2

'PCDHA7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S769. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PCDHA7 MUTATED	1	3
PCDHA7 WILD-TYPE	22	15

'PCDHA7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S770. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PCDHA7 MUTATED	1	3
PCDHA7 WILD-TYPE	19	18

'PCDHA7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S771. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PCDHA7 MUTATED	3	1
PCDHA7 WILD-TYPE	12	13

'PCDHA7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S772. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PCDHA7 MUTATED	1	2	1
PCDHA7 WILD-TYPE	4	11	10

'PCDHA7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0211 (Fisher's exact test), Q value = 1

Table S773. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PCDHA7 MUTATED	4	0
PCDHA7 WILD-TYPE	5	12

Figure S36. Get High-res Image Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

'PCDHA7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00691 (Fisher's exact test), Q value = 1

Table S774. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PCDHA7 MUTATED	4	0	0
PCDHA7 WILD-TYPE	3	9	5

Figure S37. Get High-res Image Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

'PCDHA7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S775. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PCDHA7 MUTATED	3	0	0	1
PCDHA7 WILD-TYPE	8	11	10	8

'PCDHA7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0477 (Fisher's exact test), Q value = 1

Table S776. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PCDHA7 MUTATED	2	0	1	0	1
PCDHA7 WILD-TYPE	4	11	6	12	4

Figure S38. Get High-res Image Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

'PCDHA7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.326 (Fisher's exact test), Q value = 1

Table S777. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PCDHA7 MUTATED	3	1
PCDHA7 WILD-TYPE	14	18

'PCDHA7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S778. Gene #83: 'PCDHA7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PCDHA7 MUTATED	1	0	1	0	2	0	0	0	0
PCDHA7 WILD-TYPE	3	5	4	6	5	1	4	1	3

'OR5H14 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S779. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
OR5H14 MUTATED	1	2
OR5H14 WILD-TYPE	22	16

'OR5H14 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S780. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
OR5H14 MUTATED	1	2
OR5H14 WILD-TYPE	19	19

'OR5H14 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S781. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
OR5H14 MUTATED	2	1
OR5H14 WILD-TYPE	13	13

'OR5H14 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S782. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
OR5H14 MUTATED	0	2	1
OR5H14 WILD-TYPE	5	11	10

'OR5H14 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S783. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
OR5H14 MUTATED	1	0
OR5H14 WILD-TYPE	8	12

'OR5H14 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S784. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
OR5H14 MUTATED	2	0	0	1
OR5H14 WILD-TYPE	9	11	10	8

'OR5H14 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S785. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
OR5H14 MUTATED	1	0	1	1	0
OR5H14 WILD-TYPE	5	11	6	11	5

'OR5H14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S786. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
OR5H14 MUTATED	2	1
OR5H14 WILD-TYPE	15	18

'OR5H14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S787. Gene #84: 'OR5H14 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
OR5H14 MUTATED	0	0	1	0	2	0	0	0	0
OR5H14 WILD-TYPE	4	5	4	6	5	1	4	1	3

'PER3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S788. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PER3 MUTATED	4	0
PER3 WILD-TYPE	19	18

'PER3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S789. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PER3 MUTATED	2	2
PER3 WILD-TYPE	18	19

'PER3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S790. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PER3 MUTATED	1	0
PER3 WILD-TYPE	14	14

'PER3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S791. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PER3 MUTATED	1	1
PER3 WILD-TYPE	8	11

'PER3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S792. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PER3 MUTATED	1	1	1	1
PER3 WILD-TYPE	10	10	9	8

'PER3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S793. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PER3 MUTATED	0	1	0	3	0
PER3 WILD-TYPE	6	10	7	9	5

'PER3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S794. Gene #85: 'PER3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PER3 MUTATED	0	2
PER3 WILD-TYPE	17	17

'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S795. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
PABPC1 MUTATED	3	4
PABPC1 WILD-TYPE	20	14

'PABPC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S796. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
PABPC1 MUTATED	3	4
PABPC1 WILD-TYPE	17	17

'PABPC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S797. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
PABPC1 MUTATED	3	2
PABPC1 WILD-TYPE	12	12

'PABPC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S798. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
PABPC1 MUTATED	0	3	2
PABPC1 WILD-TYPE	5	10	9

'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S799. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
PABPC1 MUTATED	1	4
PABPC1 WILD-TYPE	8	8

'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S800. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
PABPC1 MUTATED	2	3	0
PABPC1 WILD-TYPE	5	6	5

'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S801. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
PABPC1 MUTATED	3	1	1	2
PABPC1 WILD-TYPE	8	10	9	7

'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 1

Table S802. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
PABPC1 MUTATED	2	1	1	1	2
PABPC1 WILD-TYPE	4	10	6	11	3

'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S803. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
PABPC1 MUTATED	4	3
PABPC1 WILD-TYPE	13	16

'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0884 (Fisher's exact test), Q value = 1

Table S804. Gene #86: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
PABPC1 MUTATED	0	0	1	1	3	1	0	1	0
PABPC1 WILD-TYPE	4	5	4	5	4	0	4	0	3

'ITGA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S805. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ITGA6 MUTATED	2	1
ITGA6 WILD-TYPE	21	17

'ITGA6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S806. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ITGA6 MUTATED	2	1
ITGA6 WILD-TYPE	18	20

'ITGA6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S807. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ITGA6 MUTATED	1	0
ITGA6 WILD-TYPE	14	14

'ITGA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.486 (Fisher's exact test), Q value = 1

Table S808. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ITGA6 MUTATED	0	2
ITGA6 WILD-TYPE	9	10

'ITGA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S809. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ITGA6 MUTATED	0	1	1	1
ITGA6 WILD-TYPE	11	10	9	8

'ITGA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S810. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ITGA6 MUTATED	0	1	0	1	1
ITGA6 WILD-TYPE	6	10	7	11	4

'ITGA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S811. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ITGA6 MUTATED	1	2
ITGA6 WILD-TYPE	16	17

'ITGA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S812. Gene #87: 'ITGA6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ITGA6 MUTATED	0	0	0	1	1	0	0	1	0
ITGA6 WILD-TYPE	4	5	5	5	6	1	4	0	3

'IGSF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S813. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
IGSF3 MUTATED	4	2
IGSF3 WILD-TYPE	19	16

'IGSF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S814. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
IGSF3 MUTATED	3	3
IGSF3 WILD-TYPE	17	18

'IGSF3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S815. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
IGSF3 MUTATED	3	2
IGSF3 WILD-TYPE	12	12

'IGSF3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S816. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
IGSF3 MUTATED	2	1	2
IGSF3 WILD-TYPE	3	12	9

'IGSF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 1

Table S817. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
IGSF3 MUTATED	3	1
IGSF3 WILD-TYPE	6	11

'IGSF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S818. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
IGSF3 MUTATED	2	0	2
IGSF3 WILD-TYPE	5	9	3

'IGSF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S819. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
IGSF3 MUTATED	3	1	1	1
IGSF3 WILD-TYPE	8	10	9	8

'IGSF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S820. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
IGSF3 MUTATED	1	1	2	1	1
IGSF3 WILD-TYPE	5	10	5	11	4

'IGSF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S821. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
IGSF3 MUTATED	3	3
IGSF3 WILD-TYPE	14	16

'IGSF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S822. Gene #88: 'IGSF3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
IGSF3 MUTATED	1	1	0	0	2	0	1	0	1
IGSF3 WILD-TYPE	3	4	5	6	5	1	3	1	2

'KRTAP1-1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S823. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
KRTAP1-1 MUTATED	2	1
KRTAP1-1 WILD-TYPE	21	17

'KRTAP1-1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S824. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
KRTAP1-1 MUTATED	2	1
KRTAP1-1 WILD-TYPE	18	20

'KRTAP1-1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S825. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
KRTAP1-1 MUTATED	1	0
KRTAP1-1 WILD-TYPE	14	14

'KRTAP1-1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S826. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
KRTAP1-1 MUTATED	1	2
KRTAP1-1 WILD-TYPE	8	10

'KRTAP1-1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S827. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
KRTAP1-1 MUTATED	1	2	0
KRTAP1-1 WILD-TYPE	6	7	5

'KRTAP1-1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S828. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
KRTAP1-1 MUTATED	0	1	0	2
KRTAP1-1 WILD-TYPE	11	10	10	7

'KRTAP1-1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S829. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
KRTAP1-1 MUTATED	1	1	0	0	1
KRTAP1-1 WILD-TYPE	5	10	7	12	4

'KRTAP1-1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S830. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
KRTAP1-1 MUTATED	1	2
KRTAP1-1 WILD-TYPE	16	17

'KRTAP1-1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S831. Gene #89: 'KRTAP1-1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
KRTAP1-1 MUTATED	0	0	0	0	2	0	0	1	0
KRTAP1-1 WILD-TYPE	4	5	5	6	5	1	4	0	3

'C15ORF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S832. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
C15ORF39 MUTATED	1	2
C15ORF39 WILD-TYPE	22	16

'C15ORF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S833. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
C15ORF39 MUTATED	2	1
C15ORF39 WILD-TYPE	18	20

'C15ORF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S834. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
C15ORF39 MUTATED	0	1
C15ORF39 WILD-TYPE	15	13

'C15ORF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S835. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
C15ORF39 MUTATED	1	2
C15ORF39 WILD-TYPE	8	10

'C15ORF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S836. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
C15ORF39 MUTATED	1	2	0
C15ORF39 WILD-TYPE	6	7	5

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S837. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
C15ORF39 MUTATED	1	1	0	1
C15ORF39 WILD-TYPE	10	10	10	8

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S838. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
C15ORF39 MUTATED	0	1	1	0	1
C15ORF39 WILD-TYPE	6	10	6	12	4

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S839. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
C15ORF39 MUTATED	1	2
C15ORF39 WILD-TYPE	16	17

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 1

Table S840. Gene #90: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
C15ORF39 MUTATED	0	0	1	0	1	0	0	1	0
C15ORF39 WILD-TYPE	4	5	4	6	6	1	4	0	3

'FBXO34 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S841. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
FBXO34 MUTATED	1	2
FBXO34 WILD-TYPE	22	16

'FBXO34 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S842. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
FBXO34 MUTATED	1	2
FBXO34 WILD-TYPE	19	19

'FBXO34 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S843. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
FBXO34 MUTATED	2	0
FBXO34 WILD-TYPE	13	14

'FBXO34 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S844. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
FBXO34 MUTATED	1	1
FBXO34 WILD-TYPE	8	11

'FBXO34 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S845. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
FBXO34 MUTATED	2	1	0	0
FBXO34 WILD-TYPE	9	10	10	9

'FBXO34 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 1

Table S846. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
FBXO34 MUTATED	0	1	2	0	0
FBXO34 WILD-TYPE	6	10	5	12	5

'FBXO34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S847. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
FBXO34 MUTATED	2	1
FBXO34 WILD-TYPE	15	18

'FBXO34 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0889 (Fisher's exact test), Q value = 1

Table S848. Gene #91: 'FBXO34 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
FBXO34 MUTATED	1	0	1	0	0	0	0	1	0
FBXO34 WILD-TYPE	3	5	4	6	7	1	4	0	3

'ZNF880 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S849. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
ZNF880 MUTATED	5	3
ZNF880 WILD-TYPE	18	15

'ZNF880 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S850. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
ZNF880 MUTATED	6	2
ZNF880 WILD-TYPE	14	19

'ZNF880 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S851. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
ZNF880 MUTATED	3	2
ZNF880 WILD-TYPE	12	12

'ZNF880 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S852. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
ZNF880 MUTATED	0	3	2
ZNF880 WILD-TYPE	5	10	9

'ZNF880 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S853. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
ZNF880 MUTATED	2	4
ZNF880 WILD-TYPE	7	8

'ZNF880 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S854. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
ZNF880 MUTATED	2	3	1
ZNF880 WILD-TYPE	5	6	4

'ZNF880 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S855. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
ZNF880 MUTATED	1	3	1	3
ZNF880 WILD-TYPE	10	8	9	6

'ZNF880 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S856. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
ZNF880 MUTATED	2	3	0	1	2
ZNF880 WILD-TYPE	4	8	7	11	3

'ZNF880 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0438 (Fisher's exact test), Q value = 1

Table S857. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
ZNF880 MUTATED	1	7
ZNF880 WILD-TYPE	16	12

Figure S39. Get High-res Image Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

'ZNF880 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S858. Gene #92: 'ZNF880 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
ZNF880 MUTATED	0	2	0	0	2	1	1	1	1
ZNF880 WILD-TYPE	4	3	5	6	5	0	3	0	2

'NBPF15 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S859. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
NBPF15 MUTATED	2	2
NBPF15 WILD-TYPE	21	16

'NBPF15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S860. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
NBPF15 MUTATED	2	2
NBPF15 WILD-TYPE	18	19

'NBPF15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S861. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #3: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	15	14
NBPF15 MUTATED	2	1
NBPF15 WILD-TYPE	13	13

'NBPF15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S862. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	5	13	11
NBPF15 MUTATED	0	2	1
NBPF15 WILD-TYPE	5	11	10

'NBPF15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S863. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
NBPF15 MUTATED	1	3
NBPF15 WILD-TYPE	8	9

'NBPF15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S864. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
NBPF15 MUTATED	2	1	1
NBPF15 WILD-TYPE	5	8	4

'NBPF15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S865. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
NBPF15 MUTATED	1	2	0	1
NBPF15 WILD-TYPE	10	9	10	8

'NBPF15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S866. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
NBPF15 MUTATED	1	2	0	0	1
NBPF15 WILD-TYPE	5	9	7	12	4

'NBPF15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S867. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
NBPF15 MUTATED	1	3
NBPF15 WILD-TYPE	16	16

'NBPF15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S868. Gene #93: 'NBPF15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5	CLUS_6	CLUS_7	CLUS_8	CLUS_9
ALL	4	5	5	6	7	1	4	1	3
NBPF15 MUTATED	1	1	0	0	1	0	1	0	0
NBPF15 WILD-TYPE	3	4	5	6	6	1	3	1	3

'SLC22A16 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S869. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	23	18
SLC22A16 MUTATED	2	1
SLC22A16 WILD-TYPE	21	17

'SLC22A16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S870. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	20	21
SLC22A16 MUTATED	2	1
SLC22A16 WILD-TYPE	18	20

'SLC22A16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S871. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #5: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	9	12
SLC22A16 MUTATED	1	2
SLC22A16 WILD-TYPE	8	10

'SLC22A16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S872. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	7	9	5
SLC22A16 MUTATED	0	2	1
SLC22A16 WILD-TYPE	7	7	4

'SLC22A16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S873. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	11	11	10	9
SLC22A16 MUTATED	1	1	0	1
SLC22A16 WILD-TYPE	10	10	10	8

'SLC22A16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S874. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4	CLUS_5
ALL	6	11	7	12	5
SLC22A16 MUTATED	0	1	0	1	1
SLC22A16 WILD-TYPE	6	10	7	11	4

'SLC22A16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S875. Gene #94: 'SLC22A16 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2
ALL	17	19
SLC22A16 MUTATED	0	2
SLC22A16 WILD-TYPE	17	17

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/DLBC-TP/19899503/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/DLBC-TP/20125263/DLBC-TP.transferedmergedcluster.txt
Number of patients = 41
Number of significantly mutated genes = 94
Number of Molecular subtypes = 10
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

Download Results

In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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