Mutation Analysis (MutSig vS2N)
Cervical Squamous Cell Carcinoma (Primary solid tumor)
22 February 2013  |  analyses__2013_02_22
Maintainer Information
Citation Information
doi:10.7908/C1ZW1J32
Maintained by Dan DiCara (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): Mutation Analysis (MutSig vS2N). Broad Institute of MIT and Harvard. doi:10.7908/C1ZW1J32
- Overview
+ Introduction
- Summary
- Results
- Significantly Mutated Genes

Column Descriptions:

  • N = number of sequenced bases in this gene across the individual set

  • nnon = number of (nonsilent) mutations in this gene across the individual set

  • nnull = number of (nonsilent) null mutations in this gene across the individual set

  • nflank = number of noncoding mutations from this gene's flanking region, across the individual set

  • nsil = number of silent mutations in this gene across the individual set

  • p = p-value (overall)

  • q = q-value, False Discovery Rate (Benjamini-Hochberg procedure)

Table 1.  Get Full Table A Ranked List of Significantly Mutated Genes. Number of significant genes found: 41. Number of genes displayed: 35. Click on a gene name to display its stick figure depicting the distribution of mutations and mutation types across the chosen gene (this feature may not be available for all significant genes).

gene N nflank nsil nnon nnull p q
PRSS48 4368 0 3 16 2 0 0
PIK3CA 16419 0 0 11 0 0 0
PRG4 17823 0 0 14 10 0 0
UGT2B10 16068 0 3 19 0 5.700001e-318 2.7e-314
CRIPAK 4017 0 0 5 5 1.2e-251 4.4e-248
PRB2 2652 0 0 6 5 8.4e-216 2.6e-212
ARID1A 22698 0 0 9 7 9.1e-132 2.4e-128
IFITM2 1872 0 3 9 1 3.9e-108 9.1e-105
C8orf44 1950 0 2 5 0 4.2e-88 8.9e-85
NFE2L2 8385 0 0 7 2 5.1e-47 9.7e-44
SSX7 2886 0 0 5 0 2.9e-46 5e-43
TCHH 22698 0 1 10 3 1.4e-36 2.1e-33
CDC27 11661 0 0 7 3 5e-34 7.3e-31
DNAJB1 4329 0 0 5 1 3.8e-31 5.1e-28
MAGEC1 14157 0 0 7 3 3.7e-28 4.7e-25
RAET1L 2925 0 0 5 0 8.4e-22 9.9e-19
SSX3 3120 1 1 6 0 2.8e-19 3.1e-16
SIGLEC11 6240 0 2 6 0 2.2e-17 2.3e-14
TEX15 43329 0 0 6 0 1.1e-11 1.1e-08
TXNDC2 7371 0 0 6 0 3.4e-11 3.2e-08
SRRM2 28197 0 0 6 2 7.9e-10 7.1e-07
ADAMTS16 15093 0 0 5 0 1.8e-09 1.5e-06
MLL2 48789 0 3 7 5 1.9e-09 1.6e-06
MYH9 27456 0 1 6 2 1.7e-08 0.000013
SYNE2 104910 0 0 10 2 1.7e-08 0.000013
TREML4 2613 0 3 5 1 3.6e-08 0.000026
CELSR2 31278 0 1 6 1 5.3e-08 0.000037
DNMBP 20631 0 0 5 2 4e-07 0.00027
MKI67 42744 0 0 6 2 9.9e-07 0.00064
APOB 68445 0 0 7 0 2.1e-06 0.0013
PCLO 63882 0 0 9 1 1e-05 0.0063
MLL3 63063 0 2 10 7 0.000014 0.0082
ZSCAN5A 6591 0 11 39 0 0.000019 0.011
LRP6 21723 0 0 5 1 0.000028 0.016
YTHDC1 9477 0 0 4 0 4e-05 0.022
+ Methods & Data
Copyright © 2013 Broad Institute TCGA GDAC as part of the TCGA Research Network. All rights reserved.
Made with Nozzle