PARADIGM pathway analysis of mRNASeq expression and copy number data
Kidney Renal Papillary Cell Carcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression and copy number data. Broad Institute of MIT and Harvard. doi:10.7908/C18C9VNM
- Overview
+ Introduction
- Summary

There were 25 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Nephrin/Neph1 signaling in the kidney podocyte 129
Angiopoietin receptor Tie2-mediated signaling 98
EGFR-dependent Endothelin signaling events 89
FOXA2 and FOXA3 transcription factor networks 76
PDGFR-alpha signaling pathway 63
Thromboxane A2 receptor signaling 50
Signaling mediated by p38-alpha and p38-beta 41
Glypican 1 network 38
BMP receptor signaling 33
Signaling events mediated by Stem cell factor receptor (c-Kit) 33
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data