HotNet pathway analysis of mutation and copy number data
Stomach Adenocarcinoma (Primary solid tumor)
23 May 2013  |  analyses__2013_05_23
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): HotNet pathway analysis of mutation and copy number data. Broad Institute of MIT and Harvard. doi:10.7908/C1MK6B0X
- Overview
+ Introduction
- Summary

There were 111 significant subnetworks identified in HotNet analysis.

- Results
- Significant subnetworks

HotNet identifies 111 altered subnetworks based on the matched somatic mutation and copy number alterations data. Table 1 showes the top 10 significant subnetworks.

Table 1.  Get Full Table Top 10 out of 111 subnetworks in ranked by p value. The last column of RepeatTimes shows how many times the subnetwork was picked up in differenct delta values.

Network No.ofgenes p-value RepeatTimes
GNG7(74),ACP6(43),GNB4(78) 3 0 4
PSMD4(76),ADRM1(1),PSMD2(82) 3 0 4
RBM12(2),ZMIZ1(45),TBC1D4(38) 3 0 4
SLPI(1),CTSS(76),CST5(1) 3 0 4
STT3A(49),PCSK7(50),CSDE1(45) 3 0 4
TOMM34(2),PRKAB2(43),PRKAA1(67) 3 0 4
TXNIP(43),SCEL(33),ZBTB32(35) 3 0 4
KLC1(69),DUSP16(38),MAPK11(75),MAPK8IP2(77) 4 0 4
KLRC1(34),KLRC3(34),KLRC2(33),KLRD1(35) 4 0 4
EMD(44),FATE1(43),BEND7(2) 3 0 3
+ Methods & Data