HotNet pathway analysis of mutation and copy number data
Kidney Renal Papillary Cell Carcinoma (Primary solid tumor)
23 September 2013  |  analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): HotNet pathway analysis of mutation and copy number data. Broad Institute of MIT and Harvard. doi:10.7908/C12Z13V5
- Overview
+ Introduction
- Summary

There were 28 significant subnetworks identified in HotNet analysis.

- Results
- Significant subnetworks

HotNet identifies 28 altered subnetworks based on the matched somatic mutation and copy number alterations data. Table 1 showes the top 10 significant subnetworks.

Table 1.  Get Full Table Top 10 out of 28 subnetworks in ranked by p value. The last column of RepeatTimes shows how many times the subnetwork was picked up in differenct delta values.

Network No.ofgenes p-value RepeatTimes
AGTR2(17),PIK3CB(33),ACE(75) 3 0 2
BAIAP2(75),DIAPH1(1),SHANK1(9) 3 0 2
DST(13),ITGB4(75),ITGA6(1) 3 0 2
EIF1AX(17),EIF5B(1),EIF5(26) 3 0 2
NOL11(75),PMPCB(64),MARK3(25) 3 0 2
ANKRD23(1),CAPN3(15),TTN(17) 3 0 1
CEACAM5(9),HNRNPM(8),PTCHD2(24) 3 0 1
EMD(17),BCLAF1(14),SYNE1(18) 3 0 1
EPOR(8),SH2B2(65),JAK3(8) 3 0 1
GAN(1),TBCB(8),UBA1(17) 3 0 1
+ Methods & Data