CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Prostate Adenocarcinoma (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C16Q1VX0
Overview
Introduction
Summary
There are 8426 mutations identified by MuTect and 310 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-CH-5737-01A-11D-1576-08 | NM_000314.4_V119F | 0.024 | 0 | 0.05 |
| TCGA-CH-5737-01A-11D-1576-08 | NM_001134420.1_A563D | 0.13 | 0 | 0.05 |
| TCGA-CH-5740-01A-11D-1576-08 | NM_000314.4_D326G | 0.064 | 0 | 0.05 |
| TCGA-CH-5752-01A-11D-1576-08 | NM_001904.3_S45P | 0.014 | 0 | 0.05 |
| TCGA-CH-5761-01A-11D-1576-08 | NM_001126112.1_C135F | 0.002 | 0 | 0.05 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.