This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.
Testing the association between copy number variation 79 focal events and 9 clinical features across 1083 patients, 418 significant findings detected with Q value < 0.25.
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amp_1p36.21 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_1q22 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_1q32.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_1q44 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_2p24.3 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', and 'HISTOLOGICAL_TYPE'.
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amp_3p25.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', and 'HISTOLOGICAL_TYPE'.
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amp_3q26.33 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_4p16.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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amp_4q12 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_5p15.33 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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amp_7p11.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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amp_7q11.21 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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amp_7q21.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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amp_7q31.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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amp_7q32.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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amp_8q24.21 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', and 'HISTOLOGICAL_TYPE'.
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amp_9q34.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_10p15.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_11p13 cnv correlated to 'HISTOLOGICAL_TYPE'.
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amp_11q24.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_12p13.32 cnv correlated to 'YEARS_TO_BIRTH' and 'RADIATION_THERAPY'.
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amp_12q14.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_12q15 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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amp_13q34 cnv correlated to 'KARNOFSKY_PERFORMANCE_SCORE'.
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amp_14q32.33 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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amp_17p13.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', and 'HISTOLOGICAL_TYPE'.
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amp_17q25.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', and 'HISTOLOGICAL_TYPE'.
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amp_19p13.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', and 'HISTOLOGICAL_TYPE'.
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amp_19p13.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', and 'HISTOLOGICAL_TYPE'.
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amp_19q12 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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amp_19q13.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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amp_xp11.21 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_1p36.32 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_1p36.23 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_1p32.3 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_1p22.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_1q42.11 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', and 'KARNOFSKY_PERFORMANCE_SCORE'.
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del_2q22.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_2q37.1 cnv correlated to 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', and 'HISTOLOGICAL_TYPE'.
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del_3p21.31 cnv correlated to 'RADIATION_THERAPY'.
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del_3q13.31 cnv correlated to 'Time to Death' and 'RADIATION_THERAPY'.
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del_4q34.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', and 'HISTOLOGICAL_TYPE'.
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del_5p15.33 cnv correlated to 'RADIATION_THERAPY' and 'HISTOLOGICAL_TYPE'.
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del_5q34 cnv correlated to 'YEARS_TO_BIRTH', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_6p25.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_6q22.31 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_6q26 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_8p23.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_8q24.3 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_9p21.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_10p15.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_10p13 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_10p11.23 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_10q23.31 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_10q26.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_11p15.5 cnv correlated to 'YEARS_TO_BIRTH', 'GENDER', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_11p15.1 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_11p11.2 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_12p13.1 cnv correlated to 'Time to Death', 'TUMOR_TISSUE_SITE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_12q12 cnv correlated to 'HISTOLOGICAL_TYPE'.
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del_12q15 cnv correlated to 'HISTOLOGICAL_TYPE'.
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del_13q14.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_13q22.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_14q13.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', 'RACE', and 'ETHNICITY'.
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del_14q24.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', and 'HISTOLOGICAL_TYPE'.
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del_14q31.3 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'GENDER', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_15q14 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_16p12.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', and 'HISTOLOGICAL_TYPE'.
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del_16q23.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_17p13.1 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_17q11.2 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'RACE'.
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del_18q23 cnv correlated to 'YEARS_TO_BIRTH'.
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del_19q13.41 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_19q13.43 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', and 'HISTOLOGICAL_TYPE'.
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del_22q13.32 cnv correlated to 'Time to Death', 'YEARS_TO_BIRTH', 'TUMOR_TISSUE_SITE', 'RADIATION_THERAPY', 'KARNOFSKY_PERFORMANCE_SCORE', 'HISTOLOGICAL_TYPE', and 'ETHNICITY'.
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del_xq21.1 cnv correlated to 'YEARS_TO_BIRTH' and 'KARNOFSKY_PERFORMANCE_SCORE'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 79 focal events and 9 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 418 significant findings detected.
Clinical Features |
Time to Death |
YEARS TO BIRTH |
TUMOR TISSUE SITE |
GENDER |
RADIATION THERAPY |
KARNOFSKY PERFORMANCE SCORE |
HISTOLOGICAL TYPE |
RACE | ETHNICITY | ||
nCNV (%) | nWild-Type | logrank test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Wilcoxon-test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
del 6q22 31 | 234 (22%) | 849 |
9.96e-12 (8.64e-11) |
4.01e-05 (0.000147) |
6.44e-07 (3.61e-06) |
0.0995 (0.178) |
0.0351 (0.0736) |
0.00692 (0.0178) |
1e-05 (3.91e-05) |
0.0988 (0.178) |
0.13 (0.223) |
del 10p15 3 | 547 (51%) | 536 |
0 (0) |
2.28e-71 (6e-70) |
1.4e-109 (4.98e-108) |
0.0645 (0.124) |
1.12e-15 (1.33e-14) |
6.84e-18 (9.93e-17) |
1e-05 (3.91e-05) |
0.00766 (0.0195) |
0.00501 (0.0133) |
del 10p13 | 547 (51%) | 536 |
0 (0) |
1.44e-71 (3.93e-70) |
6.21e-111 (2.32e-109) |
0.0265 (0.058) |
9.39e-17 (1.31e-15) |
2.63e-16 (3.53e-15) |
1e-05 (3.91e-05) |
0.016 (0.0366) |
0.00501 (0.0133) |
del 10p11 23 | 552 (51%) | 531 |
0 (0) |
3.67e-75 (1.09e-73) |
4.92e-114 (1.94e-112) |
0.0485 (0.097) |
6.1e-16 (7.6e-15) |
2.49e-19 (3.84e-18) |
1e-05 (3.91e-05) |
0.00155 (0.00461) |
0.00325 (0.00897) |
amp 7p11 2 | 629 (58%) | 454 |
0 (0) |
1.71e-68 (4.34e-67) |
3.58e-104 (1.21e-102) |
0.289 (0.431) |
8.74e-14 (8.75e-13) |
2.26e-19 (3.56e-18) |
1e-05 (3.91e-05) |
0.00508 (0.0135) |
0.0077 (0.0195) |
amp 7q11 21 | 576 (53%) | 507 |
0 (0) |
4.47e-55 (9.94e-54) |
1.36e-84 (4.2e-83) |
0.323 (0.466) |
5.95e-11 (4.81e-10) |
8.71e-14 (8.75e-13) |
1e-05 (3.91e-05) |
0.00298 (0.00837) |
0.00829 (0.0208) |
amp 7q21 2 | 630 (58%) | 453 |
0 (0) |
4.83e-50 (1.01e-48) |
9.69e-72 (2.75e-70) |
0.755 (0.851) |
1.19e-11 (1.02e-10) |
3.39e-12 (3.02e-11) |
1e-05 (3.91e-05) |
0.00132 (0.00399) |
0.00264 (0.00757) |
amp 7q31 2 | 640 (59%) | 443 |
0 (0) |
5.49e-40 (1.05e-38) |
3.92e-59 (9.29e-58) |
0.802 (0.886) |
1.49e-09 (1.02e-08) |
2.97e-09 (1.95e-08) |
1e-05 (3.91e-05) |
0.00839 (0.0209) |
0.00285 (0.00806) |
amp 7q32 3 | 653 (60%) | 430 |
0 (0) |
1.31e-40 (2.59e-39) |
5.3e-58 (1.22e-56) |
0.801 (0.886) |
1.74e-10 (1.33e-09) |
4.21e-09 (2.72e-08) |
1e-05 (3.91e-05) |
0.00604 (0.0158) |
0.00153 (0.00457) |
amp xp11 21 | 104 (10%) | 979 |
0.000448 (0.00144) |
3.21e-06 (1.71e-05) |
1.89e-05 (7.2e-05) |
0.0284 (0.0613) |
0.00971 (0.024) |
0.0254 (0.0559) |
1e-05 (3.91e-05) |
0.568 (0.692) |
0.0304 (0.0654) |
del 9p21 3 | 589 (54%) | 494 |
0 (0) |
3.58e-30 (5.91e-29) |
5.89e-38 (1.07e-36) |
0.387 (0.535) |
4.11e-10 (3.04e-09) |
4.66e-13 (4.36e-12) |
1e-05 (3.91e-05) |
0.015 (0.0348) |
0.0636 (0.123) |
del 10q23 31 | 622 (57%) | 461 |
0 (0) |
8.17e-64 (2e-62) |
2.51e-118 (1.05e-116) |
0.663 (0.773) |
3.55e-19 (5.37e-18) |
2.2e-18 (3.26e-17) |
1e-05 (3.91e-05) |
0.00702 (0.018) |
0.00831 (0.0208) |
del 10q26 3 | 659 (61%) | 424 |
0 (0) |
4.8e-50 (1.01e-48) |
7.75e-97 (2.5e-95) |
0.9 (0.955) |
8.23e-17 (1.17e-15) |
3.22e-16 (4.24e-15) |
1e-05 (3.91e-05) |
0.00837 (0.0209) |
0.0271 (0.0592) |
del 14q13 1 | 244 (23%) | 839 |
1.86e-10 (1.4e-09) |
1.2e-09 (8.46e-09) |
2.96e-12 (2.66e-11) |
0.377 (0.523) |
0.0203 (0.0459) |
0.00597 (0.0157) |
1e-05 (3.91e-05) |
0.0466 (0.0938) |
0.0569 (0.112) |
amp 1q32 1 | 203 (19%) | 880 |
2.28e-12 (2.08e-11) |
3.54e-13 (3.36e-12) |
5.39e-16 (6.85e-15) |
0.693 (0.796) |
0.017 (0.0388) |
0.000164 (0.000552) |
1e-05 (3.91e-05) |
0.39 (0.538) |
0.0146 (0.034) |
amp 9q34 3 | 139 (13%) | 944 |
0.0254 (0.0559) |
0.0443 (0.0903) |
0.000364 (0.00119) |
0.0798 (0.149) |
0.0856 (0.157) |
0.124 (0.214) |
0.00056 (0.00179) |
0.222 (0.35) |
0.816 (0.894) |
amp 12q14 1 | 171 (16%) | 912 |
6.66e-16 (8.17e-15) |
7.97e-06 (3.91e-05) |
7.18e-14 (7.51e-13) |
0.673 (0.781) |
0.00811 (0.0204) |
0.117 (0.204) |
1e-05 (3.91e-05) |
0.316 (0.457) |
0.0336 (0.0714) |
amp 12q15 | 110 (10%) | 973 |
2.55e-10 (1.91e-09) |
4.78e-05 (0.000174) |
1.49e-12 (1.38e-11) |
0.185 (0.303) |
0.0442 (0.0902) |
0.0364 (0.0761) |
1e-05 (3.91e-05) |
0.359 (0.506) |
0.0172 (0.0391) |
amp 19q12 | 245 (23%) | 838 |
0 (0) |
4.86e-16 (6.28e-15) |
3.12e-38 (5.83e-37) |
0.462 (0.605) |
6.89e-08 (4.15e-07) |
9.53e-05 (0.000334) |
1e-05 (3.91e-05) |
0.0403 (0.0829) |
0.582 (0.701) |
amp 19q13 2 | 230 (21%) | 853 |
0 (0) |
1.81e-15 (2.11e-14) |
9.95e-34 (1.73e-32) |
0.407 (0.554) |
5.99e-07 (3.38e-06) |
0.000304 (0.000995) |
1e-05 (3.91e-05) |
0.0337 (0.0714) |
0.567 (0.692) |
del 1p22 1 | 233 (22%) | 850 |
0 (0) |
0.00387 (0.0106) |
2.27e-30 (3.85e-29) |
0.5 (0.637) |
2.08e-14 (2.28e-13) |
0.000136 (0.000467) |
1e-05 (3.91e-05) |
0.423 (0.569) |
0.139 (0.237) |
del 13q14 2 | 381 (35%) | 702 |
3.31e-05 (0.000122) |
0.0605 (0.118) |
1.23e-06 (6.72e-06) |
0.122 (0.212) |
0.00263 (0.00757) |
0.00468 (0.0126) |
1e-05 (3.91e-05) |
0.573 (0.693) |
0.264 (0.403) |
del 13q22 1 | 364 (34%) | 719 |
1.74e-05 (6.64e-05) |
0.013 (0.0306) |
6.34e-06 (3.24e-05) |
0.268 (0.407) |
0.0151 (0.0349) |
0.00209 (0.0061) |
0.0001 (0.000349) |
0.56 (0.689) |
0.142 (0.242) |
del 17q11 2 | 91 (8%) | 992 |
3.78e-08 (2.34e-07) |
0.000205 (0.000684) |
9.35e-07 (5.19e-06) |
0.912 (0.964) |
0.116 (0.204) |
0.0111 (0.027) |
6e-05 (0.000214) |
0.0845 (0.156) |
0.398 (0.542) |
del 19q13 41 | 366 (34%) | 717 |
0 (0) |
4.16e-08 (2.55e-07) |
3.95e-34 (7.02e-33) |
0.193 (0.312) |
1.35e-08 (8.5e-08) |
5.97e-05 (0.000214) |
1e-05 (3.91e-05) |
0.808 (0.89) |
0.146 (0.248) |
del 22q13 32 | 289 (27%) | 794 |
1.61e-11 (1.36e-10) |
1.31e-10 (1.02e-09) |
1.22e-16 (1.67e-15) |
0.531 (0.663) |
0.000173 (0.000581) |
0.00307 (0.00855) |
1e-05 (3.91e-05) |
0.308 (0.45) |
0.117 (0.204) |
amp 1p36 21 | 103 (10%) | 980 |
8.52e-14 (8.75e-13) |
3.52e-08 (2.2e-07) |
9.73e-16 (1.17e-14) |
0.53 (0.663) |
0.052 (0.103) |
0.00265 (0.00757) |
1e-05 (3.91e-05) |
0.437 (0.578) |
1 (1.00) |
amp 1q22 | 143 (13%) | 940 |
0.0214 (0.0481) |
0.00137 (0.00413) |
3.81e-06 (2.01e-05) |
0.363 (0.509) |
0.171 (0.285) |
0.0481 (0.0966) |
3e-05 (0.000112) |
0.342 (0.486) |
0.107 (0.19) |
amp 1q44 | 128 (12%) | 955 |
2.82e-06 (1.51e-05) |
4.72e-06 (2.43e-05) |
5.06e-09 (3.24e-08) |
0.295 (0.436) |
0.123 (0.212) |
0.00305 (0.00853) |
1e-05 (3.91e-05) |
0.415 (0.563) |
0.809 (0.89) |
amp 3q26 33 | 129 (12%) | 954 |
3.64e-14 (3.92e-13) |
8.37e-10 (5.95e-09) |
8.32e-15 (9.39e-14) |
0.392 (0.539) |
0.186 (0.304) |
0.000652 (0.00206) |
1e-05 (3.91e-05) |
0.34 (0.485) |
0.077 (0.144) |
amp 4q12 | 138 (13%) | 945 |
4.93e-10 (3.61e-09) |
4.41e-06 (2.29e-05) |
4.38e-11 (3.58e-10) |
0.167 (0.279) |
0.086 (0.157) |
0.0486 (0.097) |
1e-05 (3.91e-05) |
0.468 (0.609) |
0.35 (0.496) |
amp 10p15 1 | 88 (8%) | 995 |
3.31e-07 (1.93e-06) |
4.45e-15 (5.11e-14) |
6.15e-10 (4.46e-09) |
0.736 (0.835) |
0.895 (0.953) |
0.000808 (0.00251) |
1e-05 (3.91e-05) |
1 (1.00) |
0.0847 (0.156) |
amp 11q24 1 | 112 (10%) | 971 |
1.57e-06 (8.5e-06) |
0.000491 (0.00157) |
5.68e-12 (4.99e-11) |
0.84 (0.91) |
0.13 (0.223) |
0.0117 (0.028) |
1e-05 (3.91e-05) |
0.289 (0.431) |
0.451 (0.595) |
amp 14q32 33 | 44 (4%) | 1039 |
0.000792 (0.00247) |
8.78e-06 (3.91e-05) |
7.54e-05 (0.000267) |
0.212 (0.335) |
0.0644 (0.124) |
0.0844 (0.156) |
0.00182 (0.00533) |
1 (1.00) |
0.254 (0.393) |
del 1p36 32 | 314 (29%) | 769 |
5.51e-09 (3.5e-08) |
0.555 (0.685) |
1.26e-14 (1.39e-13) |
0.588 (0.704) |
5.48e-08 (3.33e-07) |
0.0215 (0.0481) |
1e-05 (3.91e-05) |
0.022 (0.0493) |
0.736 (0.835) |
del 1p36 23 | 344 (32%) | 739 |
1.37e-05 (5.3e-05) |
0.18 (0.295) |
1.23e-10 (9.74e-10) |
0.467 (0.609) |
4.42e-07 (2.55e-06) |
0.00254 (0.00733) |
1e-05 (3.91e-05) |
0.046 (0.0933) |
1 (1.00) |
del 1p32 3 | 256 (24%) | 827 |
9.31e-14 (9.2e-13) |
0.211 (0.335) |
1.69e-27 (2.73e-26) |
1 (1.00) |
3.12e-13 (3e-12) |
0.00142 (0.00425) |
1e-05 (3.91e-05) |
0.0379 (0.0783) |
0.279 (0.42) |
del 2q22 1 | 68 (6%) | 1015 |
0.00412 (0.0111) |
0.0169 (0.0386) |
0.00558 (0.0147) |
0.899 (0.955) |
0.297 (0.438) |
0.0771 (0.144) |
0.00396 (0.0107) |
0.369 (0.516) |
0.105 (0.187) |
del 6q26 | 259 (24%) | 824 |
1.63e-11 (1.36e-10) |
0.000142 (0.000486) |
2.65e-09 (1.76e-08) |
0.17 (0.283) |
0.00225 (0.00652) |
0.00312 (0.00865) |
1e-05 (3.91e-05) |
0.23 (0.361) |
0.276 (0.418) |
del 8p23 2 | 88 (8%) | 995 |
0.000161 (0.000544) |
6.13e-05 (0.000218) |
1.07e-05 (4.16e-05) |
0.822 (0.896) |
0.0111 (0.027) |
0.301 (0.441) |
0.00012 (0.000414) |
0.0141 (0.0331) |
0.571 (0.693) |
del 14q31 3 | 274 (25%) | 809 |
0.00337 (0.00924) |
0.0713 (0.135) |
0.0427 (0.0874) |
0.0559 (0.11) |
0.323 (0.466) |
0.25 (0.39) |
0.0872 (0.159) |
0.0921 (0.167) |
0.859 (0.924) |
del 16q23 1 | 127 (12%) | 956 |
1.29e-09 (8.97e-09) |
5.91e-05 (0.000213) |
6.77e-10 (4.86e-09) |
0.849 (0.916) |
0.0909 (0.165) |
0.0112 (0.0271) |
1e-05 (3.91e-05) |
0.326 (0.469) |
0.811 (0.89) |
del 17p13 1 | 114 (11%) | 969 |
1.88e-09 (1.27e-08) |
4.99e-07 (2.84e-06) |
1.57e-13 (1.53e-12) |
0.16 (0.27) |
0.0344 (0.0727) |
0.0134 (0.0315) |
1e-05 (3.91e-05) |
0.598 (0.711) |
0.458 (0.602) |
del 19q13 43 | 354 (33%) | 729 |
0 (0) |
4.72e-14 (5e-13) |
2.06e-41 (4.18e-40) |
0.293 (0.435) |
1.43e-09 (9.88e-09) |
4.12e-06 (2.15e-05) |
1e-05 (3.91e-05) |
0.176 (0.291) |
0.193 (0.312) |
amp 3p25 3 | 84 (8%) | 999 |
0.0319 (0.068) |
0.0366 (0.0764) |
0.000888 (0.00273) |
0.0835 (0.155) |
0.687 (0.792) |
0.451 (0.595) |
0.00972 (0.024) |
0.894 (0.953) |
0.559 (0.688) |
amp 4p16 3 | 70 (6%) | 1013 |
0.0115 (0.0277) |
0.0463 (0.0934) |
0.00633 (0.0164) |
0.531 (0.663) |
0.02 (0.0452) |
0.588 (0.704) |
0.0451 (0.0917) |
0.491 (0.63) |
0.763 (0.851) |
amp 5p15 33 | 76 (7%) | 1007 |
0.000888 (0.00273) |
0.0368 (0.0765) |
1.23e-06 (6.72e-06) |
0.47 (0.611) |
0.118 (0.205) |
0.865 (0.928) |
2e-05 (7.52e-05) |
0.273 (0.414) |
1 (1.00) |
amp 17p13 2 | 74 (7%) | 1009 |
0.00322 (0.00891) |
0.0107 (0.0261) |
0.00377 (0.0103) |
0.0664 (0.127) |
0.576 (0.696) |
0.809 (0.89) |
0.0044 (0.0118) |
0.52 (0.657) |
0.762 (0.851) |
amp 17q25 1 | 126 (12%) | 957 |
9.1e-06 (3.91e-05) |
1.93e-05 (7.28e-05) |
0.0017 (0.00503) |
0.103 (0.184) |
0.912 (0.964) |
0.923 (0.967) |
0.0224 (0.0499) |
0.716 (0.817) |
0.626 (0.737) |
del 4q34 3 | 230 (21%) | 853 |
3.46e-05 (0.000127) |
0.0122 (0.0291) |
1.5e-05 (5.77e-05) |
0.114 (0.201) |
0.252 (0.39) |
0.202 (0.324) |
0.00123 (0.00374) |
0.552 (0.682) |
0.347 (0.492) |
del 6p25 3 | 138 (13%) | 945 |
1.65e-07 (9.75e-07) |
0.0347 (0.0729) |
0.00607 (0.0159) |
0.927 (0.967) |
0.51 (0.647) |
0.131 (0.225) |
0.0577 (0.113) |
0.198 (0.32) |
0.49 (0.63) |
del 11p15 1 | 176 (16%) | 907 |
0.0903 (0.164) |
0.679 (0.785) |
0.0697 (0.132) |
0.0372 (0.0771) |
0.0243 (0.0541) |
0.305 (0.447) |
0.00023 (0.000764) |
0.463 (0.605) |
0.528 (0.662) |
del 14q24 2 | 290 (27%) | 793 |
0.00176 (0.00519) |
0.0667 (0.127) |
0.0134 (0.0315) |
0.0602 (0.117) |
0.42 (0.566) |
0.178 (0.293) |
0.0504 (0.1) |
0.162 (0.272) |
0.483 (0.623) |
del 15q14 | 212 (20%) | 871 |
2.76e-07 (1.62e-06) |
2.63e-06 (1.42e-05) |
4.08e-09 (2.66e-08) |
0.351 (0.497) |
0.586 (0.704) |
0.0318 (0.068) |
1e-05 (3.91e-05) |
0.603 (0.716) |
0.568 (0.692) |
del 16p12 2 | 114 (11%) | 969 |
1.53e-10 (1.19e-09) |
1.07e-07 (6.4e-07) |
8.05e-11 (6.43e-10) |
0.368 (0.516) |
0.0611 (0.118) |
0.421 (0.567) |
1e-05 (3.91e-05) |
0.572 (0.693) |
1 (1.00) |
amp 8q24 21 | 169 (16%) | 914 |
0.000447 (0.00144) |
7.58e-05 (0.000267) |
0.000788 (0.00247) |
0.865 (0.928) |
0.424 (0.569) |
0.212 (0.335) |
0.00058 (0.00184) |
0.452 (0.595) |
0.204 (0.326) |
amp 19p13 3 | 372 (34%) | 711 |
0.0101 (0.0247) |
5.05e-05 (0.000183) |
2.19e-09 (1.47e-08) |
0.437 (0.578) |
0.763 (0.851) |
0.994 (1.00) |
1e-05 (3.91e-05) |
0.354 (0.499) |
0.52 (0.657) |
amp 19p13 2 | 368 (34%) | 715 |
0.000258 (0.000855) |
4.93e-07 (2.82e-06) |
1.98e-11 (1.64e-10) |
0.173 (0.286) |
0.595 (0.709) |
0.301 (0.441) |
1e-05 (3.91e-05) |
0.497 (0.635) |
0.516 (0.654) |
del 1q42 11 | 77 (7%) | 1006 |
0.0283 (0.0613) |
0.0334 (0.0711) |
0.0576 (0.113) |
0.549 (0.68) |
0.481 (0.623) |
0.0152 (0.0349) |
0.432 (0.576) |
0.211 (0.335) |
0.763 (0.851) |
del 8q24 3 | 78 (7%) | 1005 |
0.0126 (0.0301) |
0.185 (0.303) |
0.0248 (0.055) |
0.34 (0.485) |
0.0127 (0.0301) |
0.868 (0.93) |
0.0845 (0.156) |
0.251 (0.39) |
1 (1.00) |
del 11p15 5 | 234 (22%) | 849 |
0.673 (0.781) |
0.000747 (0.00235) |
0.417 (0.563) |
0.0515 (0.102) |
0.0146 (0.034) |
0.595 (0.709) |
3e-05 (0.000112) |
0.798 (0.885) |
1 (1.00) |
del 11p11 2 | 159 (15%) | 924 |
0.00283 (0.00806) |
0.377 (0.523) |
0.000289 (0.000952) |
0.258 (0.398) |
0.00293 (0.00827) |
0.635 (0.747) |
0.00012 (0.000414) |
0.657 (0.769) |
0.825 (0.897) |
del 12p13 1 | 109 (10%) | 974 |
0.0581 (0.113) |
0.483 (0.623) |
0.00631 (0.0164) |
0.61 (0.721) |
0.154 (0.261) |
0.844 (0.912) |
0.0114 (0.0275) |
0.287 (0.43) |
0.115 (0.203) |
amp 2p24 3 | 72 (7%) | 1011 |
0.0739 (0.139) |
0.689 (0.793) |
0.00715 (0.0182) |
0.462 (0.605) |
0.311 (0.451) |
0.372 (0.519) |
0.0675 (0.128) |
0.821 (0.896) |
0.758 (0.851) |
del 2q37 1 | 121 (11%) | 962 |
0.383 (0.53) |
0.0283 (0.0613) |
0.1 (0.18) |
0.495 (0.635) |
0.25 (0.39) |
0.497 (0.635) |
0.00613 (0.016) |
0.393 (0.539) |
1 (1.00) |
del 5q34 | 132 (12%) | 951 |
0.396 (0.54) |
0.0929 (0.168) |
0.926 (0.967) |
0.158 (0.267) |
0.00179 (0.00527) |
0.549 (0.68) |
0.00016 (0.000544) |
0.697 (0.798) |
1 (1.00) |
amp 12p13 32 | 152 (14%) | 931 |
0.833 (0.904) |
0.0291 (0.0626) |
0.54 (0.671) |
0.287 (0.43) |
0.00976 (0.024) |
0.841 (0.91) |
0.321 (0.464) |
0.745 (0.841) |
0.823 (0.896) |
del 3q13 31 | 95 (9%) | 988 |
0.114 (0.201) |
0.742 (0.84) |
0.237 (0.371) |
1 (1.00) |
0.0722 (0.136) |
0.43 (0.574) |
0.665 (0.773) |
0.481 (0.623) |
1 (1.00) |
del 5p15 33 | 106 (10%) | 977 |
0.281 (0.422) |
0.647 (0.757) |
1 (1.00) |
0.679 (0.785) |
0.000375 (0.00122) |
0.278 (0.419) |
0.0255 (0.0559) |
0.745 (0.841) |
1 (1.00) |
del xq21 1 | 183 (17%) | 900 |
0.49 (0.63) |
0.0388 (0.0799) |
0.169 (0.281) |
0.681 (0.787) |
0.564 (0.692) |
0.0989 (0.178) |
0.638 (0.749) |
0.694 (0.796) |
1 (1.00) |
amp 11p13 | 59 (5%) | 1024 |
0.707 (0.808) |
0.904 (0.958) |
0.79 (0.877) |
0.416 (0.563) |
0.432 (0.576) |
0.427 (0.571) |
0.114 (0.201) |
0.926 (0.967) |
0.31 (0.451) |
amp 13q34 | 54 (5%) | 1029 |
0.578 (0.697) |
0.976 (1.00) |
0.332 (0.476) |
0.396 (0.54) |
1 (1.00) |
0.0801 (0.149) |
0.583 (0.701) |
0.778 (0.866) |
1 (1.00) |
del 3p21 31 | 108 (10%) | 975 |
0.937 (0.973) |
0.259 (0.398) |
1 (1.00) |
0.918 (0.967) |
0.0012 (0.00366) |
0.19 (0.31) |
0.589 (0.704) |
0.721 (0.82) |
0.2 (0.322) |
del 12q12 | 146 (13%) | 937 |
0.8 (0.886) |
0.766 (0.854) |
0.929 (0.967) |
0.719 (0.819) |
0.29 (0.431) |
0.502 (0.638) |
0.00116 (0.00355) |
0.201 (0.323) |
0.257 (0.397) |
del 12q15 | 141 (13%) | 942 |
0.983 (1.00) |
0.762 (0.851) |
0.528 (0.662) |
0.855 (0.921) |
0.392 (0.539) |
0.948 (0.983) |
0.00702 (0.018) |
0.175 (0.29) |
1 (1.00) |
del 18q23 | 151 (14%) | 932 |
0.565 (0.692) |
0.0625 (0.121) |
0.661 (0.772) |
0.534 (0.664) |
0.297 (0.438) |
0.522 (0.657) |
0.264 (0.403) |
0.227 (0.357) |
0.262 (0.402) |
del 1q44 | 69 (6%) | 1014 |
0.203 (0.325) |
0.207 (0.33) |
0.619 (0.729) |
1 (1.00) |
0.309 (0.45) |
0.392 (0.539) |
0.928 (0.967) |
0.931 (0.967) |
1 (1.00) |
del 3q29 | 107 (10%) | 976 |
0.434 (0.577) |
0.891 (0.951) |
0.361 (0.507) |
0.607 (0.719) |
0.334 (0.478) |
0.167 (0.279) |
0.522 (0.657) |
0.917 (0.967) |
0.609 (0.721) |
del xp22 2 | 227 (21%) | 856 |
0.93 (0.967) |
0.273 (0.414) |
0.823 (0.896) |
0.289 (0.431) |
0.25 (0.39) |
0.166 (0.279) |
0.876 (0.936) |
0.923 (0.967) |
0.571 (0.693) |
P value = 8.52e-14 (logrank test), Q value = 8.8e-13
Table S1. Gene #1: 'amp_1p36.21' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 1(1P36.21) MUTATED | 103 | 85 | 0.1 - 92.7 (12.5) |
AMP PEAK 1(1P36.21) WILD-TYPE | 976 | 506 | 0.0 - 211.2 (16.2) |
Figure S1. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #1: 'Time to Death'
![](D1V1.png)
P value = 3.52e-08 (Wilcoxon-test), Q value = 2.2e-07
Table S2. Gene #1: 'amp_1p36.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 1(1P36.21) MUTATED | 103 | 58.6 (13.0) |
AMP PEAK 1(1P36.21) WILD-TYPE | 979 | 49.9 (15.8) |
Figure S2. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D1V2.png)
P value = 9.73e-16 (Fisher's exact test), Q value = 1.2e-14
Table S3. Gene #1: 'amp_1p36.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 1(1P36.21) MUTATED | 91 | 12 |
AMP PEAK 1(1P36.21) WILD-TYPE | 480 | 500 |
Figure S3. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D1V3.png)
P value = 0.052 (Fisher's exact test), Q value = 0.1
Table S4. Gene #1: 'amp_1p36.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 1(1P36.21) MUTATED | 17 | 83 |
AMP PEAK 1(1P36.21) WILD-TYPE | 241 | 684 |
Figure S4. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D1V5.png)
P value = 0.00265 (Wilcoxon-test), Q value = 0.0076
Table S5. Gene #1: 'amp_1p36.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 1(1P36.21) MUTATED | 66 | 76.7 (14.0) |
AMP PEAK 1(1P36.21) WILD-TYPE | 664 | 81.7 (14.7) |
Figure S5. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D1V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S6. Gene #1: 'amp_1p36.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 1(1P36.21) MUTATED | 9 | 0 | 0 | 3 | 1 | 90 |
AMP PEAK 1(1P36.21) WILD-TYPE | 185 | 28 | 129 | 186 | 17 | 435 |
Figure S6. Get High-res Image Gene #1: 'amp_1p36.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D1V7.png)
P value = 0.0214 (logrank test), Q value = 0.048
Table S7. Gene #2: 'amp_1q22' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 2(1Q22) MUTATED | 143 | 94 | 0.1 - 211.2 (14.6) |
AMP PEAK 2(1Q22) WILD-TYPE | 936 | 497 | 0.0 - 182.3 (16.0) |
Figure S7. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #1: 'Time to Death'
![](D2V1.png)
P value = 0.00137 (Wilcoxon-test), Q value = 0.0041
Table S8. Gene #2: 'amp_1q22' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 2(1Q22) MUTATED | 143 | 54.4 (15.5) |
AMP PEAK 2(1Q22) WILD-TYPE | 939 | 50.2 (15.8) |
Figure S8. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D2V2.png)
P value = 3.81e-06 (Fisher's exact test), Q value = 2e-05
Table S9. Gene #2: 'amp_1q22' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 2(1Q22) MUTATED | 101 | 42 |
AMP PEAK 2(1Q22) WILD-TYPE | 470 | 470 |
Figure S9. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D2V3.png)
P value = 0.0481 (Wilcoxon-test), Q value = 0.097
Table S10. Gene #2: 'amp_1q22' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 2(1Q22) MUTATED | 98 | 78.8 (14.5) |
AMP PEAK 2(1Q22) WILD-TYPE | 632 | 81.7 (14.7) |
Figure S10. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D2V6.png)
P value = 3e-05 (Fisher's exact test), Q value = 0.00011
Table S11. Gene #2: 'amp_1q22' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 2(1Q22) MUTATED | 19 | 1 | 6 | 17 | 3 | 97 |
AMP PEAK 2(1Q22) WILD-TYPE | 175 | 27 | 123 | 172 | 15 | 428 |
Figure S11. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D2V7.png)
P value = 0.107 (Fisher's exact test), Q value = 0.19
Table S12. Gene #2: 'amp_1q22' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 2(1Q22) MUTATED | 2 | 121 |
AMP PEAK 2(1Q22) WILD-TYPE | 42 | 798 |
Figure S12. Get High-res Image Gene #2: 'amp_1q22' versus Clinical Feature #9: 'ETHNICITY'
![](D2V9.png)
P value = 2.28e-12 (logrank test), Q value = 2.1e-11
Table S13. Gene #3: 'amp_1q32.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 3(1Q32.1) MUTATED | 202 | 151 | 0.1 - 211.2 (13.3) |
AMP PEAK 3(1Q32.1) WILD-TYPE | 877 | 440 | 0.0 - 182.3 (16.6) |
Figure S13. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #1: 'Time to Death'
![](D3V1.png)
P value = 3.54e-13 (Wilcoxon-test), Q value = 3.4e-12
Table S14. Gene #3: 'amp_1q32.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 3(1Q32.1) MUTATED | 203 | 57.8 (14.0) |
AMP PEAK 3(1Q32.1) WILD-TYPE | 879 | 49.1 (15.7) |
Figure S14. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D3V2.png)
P value = 5.39e-16 (Fisher's exact test), Q value = 6.8e-15
Table S15. Gene #3: 'amp_1q32.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 3(1Q32.1) MUTATED | 158 | 45 |
AMP PEAK 3(1Q32.1) WILD-TYPE | 413 | 467 |
Figure S15. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D3V3.png)
P value = 0.017 (Fisher's exact test), Q value = 0.039
Table S16. Gene #3: 'amp_1q32.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 3(1Q32.1) MUTATED | 36 | 159 |
AMP PEAK 3(1Q32.1) WILD-TYPE | 222 | 608 |
Figure S16. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D3V5.png)
P value = 0.000164 (Wilcoxon-test), Q value = 0.00055
Table S17. Gene #3: 'amp_1q32.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 3(1Q32.1) MUTATED | 138 | 77.2 (15.0) |
AMP PEAK 3(1Q32.1) WILD-TYPE | 592 | 82.2 (14.5) |
Figure S17. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D3V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S18. Gene #3: 'amp_1q32.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 3(1Q32.1) MUTATED | 23 | 7 | 7 | 15 | 5 | 146 |
AMP PEAK 3(1Q32.1) WILD-TYPE | 171 | 21 | 122 | 174 | 13 | 379 |
Figure S18. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D3V7.png)
P value = 0.0146 (Fisher's exact test), Q value = 0.034
Table S19. Gene #3: 'amp_1q32.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 3(1Q32.1) MUTATED | 2 | 172 |
AMP PEAK 3(1Q32.1) WILD-TYPE | 42 | 747 |
Figure S19. Get High-res Image Gene #3: 'amp_1q32.1' versus Clinical Feature #9: 'ETHNICITY'
![](D3V9.png)
P value = 2.82e-06 (logrank test), Q value = 1.5e-05
Table S20. Gene #4: 'amp_1q44' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 4(1Q44) MUTATED | 128 | 92 | 0.1 - 211.2 (14.3) |
AMP PEAK 4(1Q44) WILD-TYPE | 951 | 499 | 0.0 - 182.3 (16.1) |
Figure S20. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #1: 'Time to Death'
![](D4V1.png)
P value = 4.72e-06 (Wilcoxon-test), Q value = 2.4e-05
Table S21. Gene #4: 'amp_1q44' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 4(1Q44) MUTATED | 128 | 56.5 (14.5) |
AMP PEAK 4(1Q44) WILD-TYPE | 954 | 50.0 (15.8) |
Figure S21. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D4V2.png)
P value = 5.06e-09 (Fisher's exact test), Q value = 3.2e-08
Table S22. Gene #4: 'amp_1q44' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 4(1Q44) MUTATED | 98 | 30 |
AMP PEAK 4(1Q44) WILD-TYPE | 473 | 482 |
Figure S22. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D4V3.png)
P value = 0.123 (Fisher's exact test), Q value = 0.21
Table S23. Gene #4: 'amp_1q44' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 4(1Q44) MUTATED | 24 | 100 |
AMP PEAK 4(1Q44) WILD-TYPE | 234 | 667 |
Figure S23. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D4V5.png)
P value = 0.00305 (Wilcoxon-test), Q value = 0.0085
Table S24. Gene #4: 'amp_1q44' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 4(1Q44) MUTATED | 84 | 77.4 (14.2) |
AMP PEAK 4(1Q44) WILD-TYPE | 646 | 81.8 (14.7) |
Figure S24. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D4V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S25. Gene #4: 'amp_1q44' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 4(1Q44) MUTATED | 15 | 1 | 5 | 10 | 3 | 94 |
AMP PEAK 4(1Q44) WILD-TYPE | 179 | 27 | 124 | 179 | 15 | 431 |
Figure S25. Get High-res Image Gene #4: 'amp_1q44' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D4V7.png)
P value = 0.0739 (logrank test), Q value = 0.14
Table S26. Gene #5: 'amp_2p24.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 5(2P24.3) MUTATED | 72 | 49 | 0.1 - 94.5 (16.0) |
AMP PEAK 5(2P24.3) WILD-TYPE | 1007 | 542 | 0.0 - 211.2 (15.7) |
Figure S26. Get High-res Image Gene #5: 'amp_2p24.3' versus Clinical Feature #1: 'Time to Death'
![](D5V1.png)
P value = 0.00715 (Fisher's exact test), Q value = 0.018
Table S27. Gene #5: 'amp_2p24.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 5(2P24.3) MUTATED | 49 | 23 |
AMP PEAK 5(2P24.3) WILD-TYPE | 522 | 489 |
Figure S27. Get High-res Image Gene #5: 'amp_2p24.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D5V3.png)
P value = 0.0675 (Fisher's exact test), Q value = 0.13
Table S28. Gene #5: 'amp_2p24.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 5(2P24.3) MUTATED | 12 | 2 | 3 | 8 | 1 | 46 |
AMP PEAK 5(2P24.3) WILD-TYPE | 182 | 26 | 126 | 181 | 17 | 479 |
Figure S28. Get High-res Image Gene #5: 'amp_2p24.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D5V7.png)
P value = 0.0319 (logrank test), Q value = 0.068
Table S29. Gene #6: 'amp_3p25.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 6(3P25.3) MUTATED | 84 | 56 | 0.2 - 127.6 (12.7) |
AMP PEAK 6(3P25.3) WILD-TYPE | 995 | 535 | 0.0 - 211.2 (15.8) |
Figure S29. Get High-res Image Gene #6: 'amp_3p25.3' versus Clinical Feature #1: 'Time to Death'
![](D6V1.png)
P value = 0.0366 (Wilcoxon-test), Q value = 0.076
Table S30. Gene #6: 'amp_3p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 6(3P25.3) MUTATED | 84 | 54.2 (15.8) |
AMP PEAK 6(3P25.3) WILD-TYPE | 998 | 50.5 (15.8) |
Figure S30. Get High-res Image Gene #6: 'amp_3p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D6V2.png)
P value = 0.000888 (Fisher's exact test), Q value = 0.0027
Table S31. Gene #6: 'amp_3p25.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 6(3P25.3) MUTATED | 59 | 25 |
AMP PEAK 6(3P25.3) WILD-TYPE | 512 | 487 |
Figure S31. Get High-res Image Gene #6: 'amp_3p25.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D6V3.png)
P value = 0.0835 (Fisher's exact test), Q value = 0.15
Table S32. Gene #6: 'amp_3p25.3' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
AMP PEAK 6(3P25.3) MUTATED | 43 | 41 |
AMP PEAK 6(3P25.3) WILD-TYPE | 409 | 590 |
Figure S32. Get High-res Image Gene #6: 'amp_3p25.3' versus Clinical Feature #4: 'GENDER'
![](D6V4.png)
P value = 0.00972 (Fisher's exact test), Q value = 0.024
Table S33. Gene #6: 'amp_3p25.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 6(3P25.3) MUTATED | 13 | 1 | 5 | 7 | 1 | 57 |
AMP PEAK 6(3P25.3) WILD-TYPE | 181 | 27 | 124 | 182 | 17 | 468 |
Figure S33. Get High-res Image Gene #6: 'amp_3p25.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D6V7.png)
P value = 3.64e-14 (logrank test), Q value = 3.9e-13
Table S34. Gene #7: 'amp_3q26.33' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 7(3Q26.33) MUTATED | 128 | 98 | 0.1 - 127.6 (10.5) |
AMP PEAK 7(3Q26.33) WILD-TYPE | 951 | 493 | 0.0 - 211.2 (16.5) |
Figure S34. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #1: 'Time to Death'
![](D7V1.png)
P value = 8.37e-10 (Wilcoxon-test), Q value = 5.9e-09
Table S35. Gene #7: 'amp_3q26.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 7(3Q26.33) MUTATED | 129 | 58.6 (12.9) |
AMP PEAK 7(3Q26.33) WILD-TYPE | 953 | 49.7 (15.8) |
Figure S35. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D7V2.png)
P value = 8.32e-15 (Fisher's exact test), Q value = 9.4e-14
Table S36. Gene #7: 'amp_3q26.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 7(3Q26.33) MUTATED | 108 | 21 |
AMP PEAK 7(3Q26.33) WILD-TYPE | 463 | 491 |
Figure S36. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D7V3.png)
P value = 0.000652 (Wilcoxon-test), Q value = 0.0021
Table S37. Gene #7: 'amp_3q26.33' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 7(3Q26.33) MUTATED | 95 | 77.4 (13.1) |
AMP PEAK 7(3Q26.33) WILD-TYPE | 635 | 81.9 (14.8) |
Figure S37. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D7V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S38. Gene #7: 'amp_3q26.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 7(3Q26.33) MUTATED | 15 | 0 | 1 | 5 | 0 | 108 |
AMP PEAK 7(3Q26.33) WILD-TYPE | 179 | 28 | 128 | 184 | 18 | 417 |
Figure S38. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D7V7.png)
P value = 0.077 (Fisher's exact test), Q value = 0.14
Table S39. Gene #7: 'amp_3q26.33' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 7(3Q26.33) MUTATED | 1 | 102 |
AMP PEAK 7(3Q26.33) WILD-TYPE | 43 | 817 |
Figure S39. Get High-res Image Gene #7: 'amp_3q26.33' versus Clinical Feature #9: 'ETHNICITY'
![](D7V9.png)
P value = 0.0115 (logrank test), Q value = 0.028
Table S40. Gene #8: 'amp_4p16.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 8(4P16.3) MUTATED | 70 | 48 | 0.2 - 94.5 (13.9) |
AMP PEAK 8(4P16.3) WILD-TYPE | 1009 | 543 | 0.0 - 211.2 (15.8) |
Figure S40. Get High-res Image Gene #8: 'amp_4p16.3' versus Clinical Feature #1: 'Time to Death'
![](D8V1.png)
P value = 0.0463 (Wilcoxon-test), Q value = 0.093
Table S41. Gene #8: 'amp_4p16.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 8(4P16.3) MUTATED | 70 | 54.2 (14.6) |
AMP PEAK 8(4P16.3) WILD-TYPE | 1012 | 50.5 (15.8) |
Figure S41. Get High-res Image Gene #8: 'amp_4p16.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D8V2.png)
P value = 0.00633 (Fisher's exact test), Q value = 0.016
Table S42. Gene #8: 'amp_4p16.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 8(4P16.3) MUTATED | 48 | 22 |
AMP PEAK 8(4P16.3) WILD-TYPE | 523 | 490 |
Figure S42. Get High-res Image Gene #8: 'amp_4p16.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D8V3.png)
P value = 0.02 (Fisher's exact test), Q value = 0.045
Table S43. Gene #8: 'amp_4p16.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 8(4P16.3) MUTATED | 9 | 58 |
AMP PEAK 8(4P16.3) WILD-TYPE | 249 | 709 |
Figure S43. Get High-res Image Gene #8: 'amp_4p16.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D8V5.png)
P value = 0.0451 (Fisher's exact test), Q value = 0.092
Table S44. Gene #8: 'amp_4p16.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 8(4P16.3) MUTATED | 12 | 1 | 3 | 7 | 1 | 46 |
AMP PEAK 8(4P16.3) WILD-TYPE | 182 | 27 | 126 | 182 | 17 | 479 |
Figure S44. Get High-res Image Gene #8: 'amp_4p16.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D8V7.png)
P value = 4.93e-10 (logrank test), Q value = 3.6e-09
Table S45. Gene #9: 'amp_4q12' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 9(4Q12) MUTATED | 138 | 101 | 0.1 - 92.7 (11.9) |
AMP PEAK 9(4Q12) WILD-TYPE | 941 | 490 | 0.0 - 211.2 (16.2) |
Figure S45. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #1: 'Time to Death'
![](D9V1.png)
P value = 4.41e-06 (Wilcoxon-test), Q value = 2.3e-05
Table S46. Gene #9: 'amp_4q12' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 9(4Q12) MUTATED | 138 | 56.2 (15.1) |
AMP PEAK 9(4Q12) WILD-TYPE | 944 | 50.0 (15.7) |
Figure S46. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D9V2.png)
P value = 4.38e-11 (Fisher's exact test), Q value = 3.6e-10
Table S47. Gene #9: 'amp_4q12' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 9(4Q12) MUTATED | 108 | 30 |
AMP PEAK 9(4Q12) WILD-TYPE | 463 | 482 |
Figure S47. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D9V3.png)
P value = 0.086 (Fisher's exact test), Q value = 0.16
Table S48. Gene #9: 'amp_4q12' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 9(4Q12) MUTATED | 25 | 108 |
AMP PEAK 9(4Q12) WILD-TYPE | 233 | 659 |
Figure S48. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D9V5.png)
P value = 0.0486 (Wilcoxon-test), Q value = 0.097
Table S49. Gene #9: 'amp_4q12' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 9(4Q12) MUTATED | 100 | 78.7 (15.4) |
AMP PEAK 9(4Q12) WILD-TYPE | 630 | 81.7 (14.5) |
Figure S49. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D9V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S50. Gene #9: 'amp_4q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 9(4Q12) MUTATED | 21 | 4 | 2 | 7 | 2 | 102 |
AMP PEAK 9(4Q12) WILD-TYPE | 173 | 24 | 127 | 182 | 16 | 423 |
Figure S50. Get High-res Image Gene #9: 'amp_4q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D9V7.png)
P value = 0.000888 (logrank test), Q value = 0.0027
Table S51. Gene #10: 'amp_5p15.33' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 10(5P15.33) MUTATED | 76 | 57 | 0.2 - 92.7 (12.9) |
AMP PEAK 10(5P15.33) WILD-TYPE | 1003 | 534 | 0.0 - 211.2 (15.9) |
Figure S51. Get High-res Image Gene #10: 'amp_5p15.33' versus Clinical Feature #1: 'Time to Death'
![](D10V1.png)
P value = 0.0368 (Wilcoxon-test), Q value = 0.076
Table S52. Gene #10: 'amp_5p15.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 10(5P15.33) MUTATED | 76 | 54.2 (16.4) |
AMP PEAK 10(5P15.33) WILD-TYPE | 1006 | 50.5 (15.7) |
Figure S52. Get High-res Image Gene #10: 'amp_5p15.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D10V2.png)
P value = 1.23e-06 (Fisher's exact test), Q value = 6.7e-06
Table S53. Gene #10: 'amp_5p15.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 10(5P15.33) MUTATED | 60 | 16 |
AMP PEAK 10(5P15.33) WILD-TYPE | 511 | 496 |
Figure S53. Get High-res Image Gene #10: 'amp_5p15.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D10V3.png)
P value = 0.118 (Fisher's exact test), Q value = 0.21
Table S54. Gene #10: 'amp_5p15.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 10(5P15.33) MUTATED | 12 | 59 |
AMP PEAK 10(5P15.33) WILD-TYPE | 246 | 708 |
Figure S54. Get High-res Image Gene #10: 'amp_5p15.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D10V5.png)
P value = 2e-05 (Fisher's exact test), Q value = 7.5e-05
Table S55. Gene #10: 'amp_5p15.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 10(5P15.33) MUTATED | 10 | 3 | 4 | 2 | 4 | 53 |
AMP PEAK 10(5P15.33) WILD-TYPE | 184 | 25 | 125 | 187 | 14 | 472 |
Figure S55. Get High-res Image Gene #10: 'amp_5p15.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D10V7.png)
P value = 0 (logrank test), Q value = 0
Table S56. Gene #11: 'amp_7p11.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 11(7P11.2) MUTATED | 628 | 476 | 0.1 - 211.2 (12.6) |
AMP PEAK 11(7P11.2) WILD-TYPE | 451 | 115 | 0.0 - 182.3 (22.1) |
Figure S56. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #1: 'Time to Death'
![](D11V1.png)
P value = 1.71e-68 (Wilcoxon-test), Q value = 4.3e-67
Table S57. Gene #11: 'amp_7p11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 11(7P11.2) MUTATED | 629 | 57.8 (13.2) |
AMP PEAK 11(7P11.2) WILD-TYPE | 453 | 41.0 (13.7) |
Figure S57. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D11V2.png)
P value = 3.58e-104 (Fisher's exact test), Q value = 1.2e-102
Table S58. Gene #11: 'amp_7p11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 11(7P11.2) MUTATED | 501 | 128 |
AMP PEAK 11(7P11.2) WILD-TYPE | 70 | 384 |
Figure S58. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D11V3.png)
P value = 8.74e-14 (Fisher's exact test), Q value = 8.8e-13
Table S59. Gene #11: 'amp_7p11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 11(7P11.2) MUTATED | 99 | 500 |
AMP PEAK 11(7P11.2) WILD-TYPE | 159 | 267 |
Figure S59. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D11V5.png)
P value = 2.26e-19 (Wilcoxon-test), Q value = 3.6e-18
Table S60. Gene #11: 'amp_7p11.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 11(7P11.2) MUTATED | 449 | 77.7 (15.3) |
AMP PEAK 11(7P11.2) WILD-TYPE | 281 | 87.1 (11.5) |
Figure S60. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D11V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S61. Gene #11: 'amp_7p11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 11(7P11.2) MUTATED | 58 | 23 | 33 | 37 | 13 | 465 |
AMP PEAK 11(7P11.2) WILD-TYPE | 136 | 5 | 96 | 152 | 5 | 60 |
Figure S61. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D11V7.png)
P value = 0.00508 (Fisher's exact test), Q value = 0.013
Table S62. Gene #11: 'amp_7p11.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 11(7P11.2) MUTATED | 1 | 12 | 54 | 540 |
AMP PEAK 11(7P11.2) WILD-TYPE | 0 | 9 | 17 | 417 |
Figure S62. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #8: 'RACE'
![](D11V8.png)
P value = 0.0077 (Fisher's exact test), Q value = 0.019
Table S63. Gene #11: 'amp_7p11.2' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 11(7P11.2) MUTATED | 16 | 527 |
AMP PEAK 11(7P11.2) WILD-TYPE | 28 | 392 |
Figure S63. Get High-res Image Gene #11: 'amp_7p11.2' versus Clinical Feature #9: 'ETHNICITY'
![](D11V9.png)
P value = 0 (logrank test), Q value = 0
Table S64. Gene #12: 'amp_7q11.21' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 12(7Q11.21) MUTATED | 575 | 432 | 0.1 - 211.2 (12.6) |
AMP PEAK 12(7Q11.21) WILD-TYPE | 504 | 159 | 0.0 - 182.3 (20.9) |
Figure S64. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #1: 'Time to Death'
![](D12V1.png)
P value = 4.47e-55 (Wilcoxon-test), Q value = 9.9e-54
Table S65. Gene #12: 'amp_7q11.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 12(7Q11.21) MUTATED | 576 | 57.8 (13.2) |
AMP PEAK 12(7Q11.21) WILD-TYPE | 506 | 42.8 (14.6) |
Figure S65. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D12V2.png)
P value = 1.36e-84 (Fisher's exact test), Q value = 4.2e-83
Table S66. Gene #12: 'amp_7q11.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 12(7Q11.21) MUTATED | 459 | 117 |
AMP PEAK 12(7Q11.21) WILD-TYPE | 112 | 395 |
Figure S66. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D12V3.png)
P value = 5.95e-11 (Fisher's exact test), Q value = 4.8e-10
Table S67. Gene #12: 'amp_7q11.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 12(7Q11.21) MUTATED | 92 | 455 |
AMP PEAK 12(7Q11.21) WILD-TYPE | 166 | 312 |
Figure S67. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D12V5.png)
P value = 8.71e-14 (Wilcoxon-test), Q value = 8.8e-13
Table S68. Gene #12: 'amp_7q11.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 12(7Q11.21) MUTATED | 407 | 77.9 (15.3) |
AMP PEAK 12(7Q11.21) WILD-TYPE | 323 | 85.5 (12.7) |
Figure S68. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D12V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S69. Gene #12: 'amp_7q11.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 12(7Q11.21) MUTATED | 51 | 20 | 31 | 35 | 10 | 429 |
AMP PEAK 12(7Q11.21) WILD-TYPE | 143 | 8 | 98 | 154 | 8 | 96 |
Figure S69. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D12V7.png)
P value = 0.00298 (Fisher's exact test), Q value = 0.0084
Table S70. Gene #12: 'amp_7q11.21' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 12(7Q11.21) MUTATED | 1 | 10 | 51 | 492 |
AMP PEAK 12(7Q11.21) WILD-TYPE | 0 | 11 | 20 | 465 |
Figure S70. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #8: 'RACE'
![](D12V8.png)
P value = 0.00829 (Fisher's exact test), Q value = 0.021
Table S71. Gene #12: 'amp_7q11.21' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 12(7Q11.21) MUTATED | 14 | 483 |
AMP PEAK 12(7Q11.21) WILD-TYPE | 30 | 436 |
Figure S71. Get High-res Image Gene #12: 'amp_7q11.21' versus Clinical Feature #9: 'ETHNICITY'
![](D12V9.png)
P value = 0 (logrank test), Q value = 0
Table S72. Gene #13: 'amp_7q21.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 13(7Q21.2) MUTATED | 629 | 455 | 0.1 - 211.2 (13.1) |
AMP PEAK 13(7Q21.2) WILD-TYPE | 450 | 136 | 0.0 - 182.3 (21.1) |
Figure S72. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #1: 'Time to Death'
![](D13V1.png)
P value = 4.83e-50 (Wilcoxon-test), Q value = 1e-48
Table S73. Gene #13: 'amp_7q21.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 13(7Q21.2) MUTATED | 630 | 56.8 (13.5) |
AMP PEAK 13(7Q21.2) WILD-TYPE | 452 | 42.4 (14.9) |
Figure S73. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D13V2.png)
P value = 9.69e-72 (Fisher's exact test), Q value = 2.8e-70
Table S74. Gene #13: 'amp_7q21.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 13(7Q21.2) MUTATED | 474 | 156 |
AMP PEAK 13(7Q21.2) WILD-TYPE | 97 | 356 |
Figure S74. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D13V3.png)
P value = 1.19e-11 (Fisher's exact test), Q value = 1e-10
Table S75. Gene #13: 'amp_7q21.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 13(7Q21.2) MUTATED | 104 | 496 |
AMP PEAK 13(7Q21.2) WILD-TYPE | 154 | 271 |
Figure S75. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D13V5.png)
P value = 3.39e-12 (Wilcoxon-test), Q value = 3e-11
Table S76. Gene #13: 'amp_7q21.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 13(7Q21.2) MUTATED | 441 | 78.4 (15.5) |
AMP PEAK 13(7Q21.2) WILD-TYPE | 289 | 85.7 (12.1) |
Figure S76. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D13V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S77. Gene #13: 'amp_7q21.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 13(7Q21.2) MUTATED | 68 | 22 | 40 | 48 | 12 | 440 |
AMP PEAK 13(7Q21.2) WILD-TYPE | 126 | 6 | 89 | 141 | 6 | 85 |
Figure S77. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D13V7.png)
P value = 0.00132 (Fisher's exact test), Q value = 0.004
Table S78. Gene #13: 'amp_7q21.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 13(7Q21.2) MUTATED | 1 | 10 | 55 | 542 |
AMP PEAK 13(7Q21.2) WILD-TYPE | 0 | 11 | 16 | 415 |
Figure S78. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #8: 'RACE'
![](D13V8.png)
P value = 0.00264 (Fisher's exact test), Q value = 0.0076
Table S79. Gene #13: 'amp_7q21.2' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 13(7Q21.2) MUTATED | 15 | 535 |
AMP PEAK 13(7Q21.2) WILD-TYPE | 29 | 384 |
Figure S79. Get High-res Image Gene #13: 'amp_7q21.2' versus Clinical Feature #9: 'ETHNICITY'
![](D13V9.png)
P value = 0 (logrank test), Q value = 0
Table S80. Gene #14: 'amp_7q31.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 14(7Q31.2) MUTATED | 639 | 450 | 0.1 - 211.2 (13.6) |
AMP PEAK 14(7Q31.2) WILD-TYPE | 440 | 141 | 0.0 - 182.3 (20.7) |
Figure S80. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #1: 'Time to Death'
![](D14V1.png)
P value = 5.49e-40 (Wilcoxon-test), Q value = 1.1e-38
Table S81. Gene #14: 'amp_7q31.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 14(7Q31.2) MUTATED | 640 | 56.1 (13.8) |
AMP PEAK 14(7Q31.2) WILD-TYPE | 442 | 43.1 (15.4) |
Figure S81. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D14V2.png)
P value = 3.92e-59 (Fisher's exact test), Q value = 9.3e-58
Table S82. Gene #14: 'amp_7q31.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 14(7Q31.2) MUTATED | 466 | 174 |
AMP PEAK 14(7Q31.2) WILD-TYPE | 105 | 338 |
Figure S82. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D14V3.png)
P value = 1.49e-09 (Fisher's exact test), Q value = 1e-08
Table S83. Gene #14: 'amp_7q31.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 14(7Q31.2) MUTATED | 111 | 496 |
AMP PEAK 14(7Q31.2) WILD-TYPE | 147 | 271 |
Figure S83. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D14V5.png)
P value = 2.97e-09 (Wilcoxon-test), Q value = 2e-08
Table S84. Gene #14: 'amp_7q31.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 14(7Q31.2) MUTATED | 444 | 78.9 (15.2) |
AMP PEAK 14(7Q31.2) WILD-TYPE | 286 | 85.0 (13.1) |
Figure S84. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D14V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S85. Gene #14: 'amp_7q31.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 14(7Q31.2) MUTATED | 75 | 21 | 47 | 52 | 13 | 432 |
AMP PEAK 14(7Q31.2) WILD-TYPE | 119 | 7 | 82 | 137 | 5 | 93 |
Figure S85. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D14V7.png)
P value = 0.00839 (Fisher's exact test), Q value = 0.021
Table S86. Gene #14: 'amp_7q31.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 14(7Q31.2) MUTATED | 1 | 11 | 54 | 553 |
AMP PEAK 14(7Q31.2) WILD-TYPE | 0 | 10 | 17 | 404 |
Figure S86. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #8: 'RACE'
![](D14V8.png)
P value = 0.00285 (Fisher's exact test), Q value = 0.0081
Table S87. Gene #14: 'amp_7q31.2' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 14(7Q31.2) MUTATED | 16 | 546 |
AMP PEAK 14(7Q31.2) WILD-TYPE | 28 | 373 |
Figure S87. Get High-res Image Gene #14: 'amp_7q31.2' versus Clinical Feature #9: 'ETHNICITY'
![](D14V9.png)
P value = 0 (logrank test), Q value = 0
Table S88. Gene #15: 'amp_7q32.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 15(7Q32.3) MUTATED | 652 | 456 | 0.1 - 211.2 (13.7) |
AMP PEAK 15(7Q32.3) WILD-TYPE | 427 | 135 | 0.0 - 182.3 (20.7) |
Figure S88. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #1: 'Time to Death'
![](D15V1.png)
P value = 1.31e-40 (Wilcoxon-test), Q value = 2.6e-39
Table S89. Gene #15: 'amp_7q32.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 15(7Q32.3) MUTATED | 653 | 56.0 (13.8) |
AMP PEAK 15(7Q32.3) WILD-TYPE | 429 | 42.9 (15.4) |
Figure S89. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D15V2.png)
P value = 5.3e-58 (Fisher's exact test), Q value = 1.2e-56
Table S90. Gene #15: 'amp_7q32.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 15(7Q32.3) MUTATED | 471 | 182 |
AMP PEAK 15(7Q32.3) WILD-TYPE | 100 | 330 |
Figure S90. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D15V3.png)
P value = 1.74e-10 (Fisher's exact test), Q value = 1.3e-09
Table S91. Gene #15: 'amp_7q32.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 15(7Q32.3) MUTATED | 112 | 508 |
AMP PEAK 15(7Q32.3) WILD-TYPE | 146 | 259 |
Figure S91. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D15V5.png)
P value = 4.21e-09 (Wilcoxon-test), Q value = 2.7e-08
Table S92. Gene #15: 'amp_7q32.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 15(7Q32.3) MUTATED | 454 | 78.9 (15.3) |
AMP PEAK 15(7Q32.3) WILD-TYPE | 276 | 85.1 (12.7) |
Figure S92. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D15V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S93. Gene #15: 'amp_7q32.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 15(7Q32.3) MUTATED | 78 | 21 | 49 | 55 | 12 | 438 |
AMP PEAK 15(7Q32.3) WILD-TYPE | 116 | 7 | 80 | 134 | 6 | 87 |
Figure S93. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D15V7.png)
P value = 0.00604 (Fisher's exact test), Q value = 0.016
Table S94. Gene #15: 'amp_7q32.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 15(7Q32.3) MUTATED | 1 | 11 | 55 | 565 |
AMP PEAK 15(7Q32.3) WILD-TYPE | 0 | 10 | 16 | 392 |
Figure S94. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #8: 'RACE'
![](D15V8.png)
P value = 0.00153 (Fisher's exact test), Q value = 0.0046
Table S95. Gene #15: 'amp_7q32.3' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 15(7Q32.3) MUTATED | 16 | 559 |
AMP PEAK 15(7Q32.3) WILD-TYPE | 28 | 360 |
Figure S95. Get High-res Image Gene #15: 'amp_7q32.3' versus Clinical Feature #9: 'ETHNICITY'
![](D15V9.png)
P value = 0.000447 (logrank test), Q value = 0.0014
Table S96. Gene #16: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 16(8Q24.21) MUTATED | 169 | 79 | 0.1 - 146.1 (18.9) |
AMP PEAK 16(8Q24.21) WILD-TYPE | 910 | 512 | 0.0 - 211.2 (15.0) |
Figure S96. Get High-res Image Gene #16: 'amp_8q24.21' versus Clinical Feature #1: 'Time to Death'
![](D16V1.png)
P value = 7.58e-05 (Wilcoxon-test), Q value = 0.00027
Table S97. Gene #16: 'amp_8q24.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 16(8Q24.21) MUTATED | 169 | 46.2 (16.2) |
AMP PEAK 16(8Q24.21) WILD-TYPE | 913 | 51.6 (15.6) |
Figure S97. Get High-res Image Gene #16: 'amp_8q24.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D16V2.png)
P value = 0.000788 (Fisher's exact test), Q value = 0.0025
Table S98. Gene #16: 'amp_8q24.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 16(8Q24.21) MUTATED | 69 | 100 |
AMP PEAK 16(8Q24.21) WILD-TYPE | 502 | 412 |
Figure S98. Get High-res Image Gene #16: 'amp_8q24.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D16V3.png)
P value = 0.00058 (Fisher's exact test), Q value = 0.0018
Table S99. Gene #16: 'amp_8q24.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 16(8Q24.21) MUTATED | 47 | 2 | 29 | 24 | 2 | 65 |
AMP PEAK 16(8Q24.21) WILD-TYPE | 147 | 26 | 100 | 165 | 16 | 460 |
Figure S99. Get High-res Image Gene #16: 'amp_8q24.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D16V7.png)
P value = 0.0254 (logrank test), Q value = 0.056
Table S100. Gene #17: 'amp_9q34.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 17(9Q34.3) MUTATED | 139 | 88 | 0.1 - 172.8 (14.2) |
AMP PEAK 17(9Q34.3) WILD-TYPE | 940 | 503 | 0.0 - 211.2 (15.9) |
Figure S100. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #1: 'Time to Death'
![](D17V1.png)
P value = 0.0443 (Wilcoxon-test), Q value = 0.09
Table S101. Gene #17: 'amp_9q34.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 17(9Q34.3) MUTATED | 139 | 52.9 (16.6) |
AMP PEAK 17(9Q34.3) WILD-TYPE | 943 | 50.5 (15.6) |
Figure S101. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D17V2.png)
P value = 0.000364 (Fisher's exact test), Q value = 0.0012
Table S102. Gene #17: 'amp_9q34.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 17(9Q34.3) MUTATED | 93 | 46 |
AMP PEAK 17(9Q34.3) WILD-TYPE | 478 | 466 |
Figure S102. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D17V3.png)
P value = 0.0798 (Fisher's exact test), Q value = 0.15
Table S103. Gene #17: 'amp_9q34.3' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
AMP PEAK 17(9Q34.3) MUTATED | 68 | 71 |
AMP PEAK 17(9Q34.3) WILD-TYPE | 384 | 560 |
Figure S103. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #4: 'GENDER'
![](D17V4.png)
P value = 0.0856 (Fisher's exact test), Q value = 0.16
Table S104. Gene #17: 'amp_9q34.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 17(9Q34.3) MUTATED | 25 | 107 |
AMP PEAK 17(9Q34.3) WILD-TYPE | 233 | 660 |
Figure S104. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D17V5.png)
P value = 0.124 (Wilcoxon-test), Q value = 0.21
Table S105. Gene #17: 'amp_9q34.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 17(9Q34.3) MUTATED | 102 | 79.1 (15.2) |
AMP PEAK 17(9Q34.3) WILD-TYPE | 628 | 81.6 (14.6) |
Figure S105. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D17V6.png)
P value = 0.00056 (Fisher's exact test), Q value = 0.0018
Table S106. Gene #17: 'amp_9q34.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 17(9Q34.3) MUTATED | 24 | 3 | 13 | 9 | 2 | 88 |
AMP PEAK 17(9Q34.3) WILD-TYPE | 170 | 25 | 116 | 180 | 16 | 437 |
Figure S106. Get High-res Image Gene #17: 'amp_9q34.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D17V7.png)
P value = 3.31e-07 (logrank test), Q value = 1.9e-06
Table S107. Gene #18: 'amp_10p15.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 18(10P15.1) MUTATED | 88 | 29 | 0.1 - 172.8 (24.0) |
AMP PEAK 18(10P15.1) WILD-TYPE | 991 | 562 | 0.0 - 211.2 (15.1) |
Figure S107. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #1: 'Time to Death'
![](D18V1.png)
P value = 4.45e-15 (Wilcoxon-test), Q value = 5.1e-14
Table S108. Gene #18: 'amp_10p15.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 18(10P15.1) MUTATED | 88 | 38.2 (12.4) |
AMP PEAK 18(10P15.1) WILD-TYPE | 994 | 51.9 (15.6) |
Figure S108. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D18V2.png)
P value = 6.15e-10 (Fisher's exact test), Q value = 4.5e-09
Table S109. Gene #18: 'amp_10p15.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 18(10P15.1) MUTATED | 19 | 69 |
AMP PEAK 18(10P15.1) WILD-TYPE | 552 | 443 |
Figure S109. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D18V3.png)
P value = 0.000808 (Wilcoxon-test), Q value = 0.0025
Table S110. Gene #18: 'amp_10p15.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 18(10P15.1) MUTATED | 58 | 86.9 (11.9) |
AMP PEAK 18(10P15.1) WILD-TYPE | 672 | 80.8 (14.8) |
Figure S110. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D18V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S111. Gene #18: 'amp_10p15.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 18(10P15.1) MUTATED | 37 | 1 | 23 | 9 | 1 | 17 |
AMP PEAK 18(10P15.1) WILD-TYPE | 157 | 27 | 106 | 180 | 17 | 508 |
Figure S111. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D18V7.png)
P value = 0.0847 (Fisher's exact test), Q value = 0.16
Table S112. Gene #18: 'amp_10p15.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 18(10P15.1) MUTATED | 7 | 73 |
AMP PEAK 18(10P15.1) WILD-TYPE | 37 | 846 |
Figure S112. Get High-res Image Gene #18: 'amp_10p15.1' versus Clinical Feature #9: 'ETHNICITY'
![](D18V9.png)
P value = 0.114 (Fisher's exact test), Q value = 0.2
Table S113. Gene #19: 'amp_11p13' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 19(11P13) MUTATED | 5 | 2 | 7 | 17 | 1 | 27 |
AMP PEAK 19(11P13) WILD-TYPE | 189 | 26 | 122 | 172 | 17 | 498 |
Figure S113. Get High-res Image Gene #19: 'amp_11p13' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D19V7.png)
P value = 1.57e-06 (logrank test), Q value = 8.5e-06
Table S114. Gene #20: 'amp_11q24.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 20(11Q24.1) MUTATED | 112 | 39 | 0.2 - 211.2 (23.0) |
AMP PEAK 20(11Q24.1) WILD-TYPE | 967 | 552 | 0.0 - 172.8 (15.1) |
Figure S114. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #1: 'Time to Death'
![](D20V1.png)
P value = 0.000491 (Wilcoxon-test), Q value = 0.0016
Table S115. Gene #20: 'amp_11q24.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 20(11Q24.1) MUTATED | 112 | 46.0 (14.0) |
AMP PEAK 20(11Q24.1) WILD-TYPE | 970 | 51.3 (15.9) |
Figure S115. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D20V2.png)
P value = 5.68e-12 (Fisher's exact test), Q value = 5e-11
Table S116. Gene #20: 'amp_11q24.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 20(11Q24.1) MUTATED | 25 | 87 |
AMP PEAK 20(11Q24.1) WILD-TYPE | 546 | 425 |
Figure S116. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D20V3.png)
P value = 0.13 (Fisher's exact test), Q value = 0.22
Table S117. Gene #20: 'amp_11q24.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 20(11Q24.1) MUTATED | 34 | 75 |
AMP PEAK 20(11Q24.1) WILD-TYPE | 224 | 692 |
Figure S117. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D20V5.png)
P value = 0.0117 (Wilcoxon-test), Q value = 0.028
Table S118. Gene #20: 'amp_11q24.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 20(11Q24.1) MUTATED | 74 | 85.0 (13.3) |
AMP PEAK 20(11Q24.1) WILD-TYPE | 656 | 80.9 (14.8) |
Figure S118. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D20V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S119. Gene #20: 'amp_11q24.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 20(11Q24.1) MUTATED | 33 | 0 | 18 | 36 | 1 | 24 |
AMP PEAK 20(11Q24.1) WILD-TYPE | 161 | 28 | 111 | 153 | 17 | 501 |
Figure S119. Get High-res Image Gene #20: 'amp_11q24.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D20V7.png)
P value = 0.0291 (Wilcoxon-test), Q value = 0.063
Table S120. Gene #21: 'amp_12p13.32' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 21(12P13.32) MUTATED | 152 | 48.1 (16.5) |
AMP PEAK 21(12P13.32) WILD-TYPE | 930 | 51.2 (15.6) |
Figure S120. Get High-res Image Gene #21: 'amp_12p13.32' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D21V2.png)
P value = 0.00976 (Fisher's exact test), Q value = 0.024
Table S121. Gene #21: 'amp_12p13.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 21(12P13.32) MUTATED | 24 | 122 |
AMP PEAK 21(12P13.32) WILD-TYPE | 234 | 645 |
Figure S121. Get High-res Image Gene #21: 'amp_12p13.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D21V5.png)
P value = 6.66e-16 (logrank test), Q value = 8.2e-15
Table S122. Gene #22: 'amp_12q14.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 22(12Q14.1) MUTATED | 170 | 134 | 0.1 - 84.3 (13.9) |
AMP PEAK 22(12Q14.1) WILD-TYPE | 909 | 457 | 0.0 - 211.2 (16.2) |
Figure S122. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #1: 'Time to Death'
![](D22V1.png)
P value = 7.97e-06 (Wilcoxon-test), Q value = 3.9e-05
Table S123. Gene #22: 'amp_12q14.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 22(12Q14.1) MUTATED | 171 | 55.7 (15.3) |
AMP PEAK 22(12Q14.1) WILD-TYPE | 911 | 49.9 (15.7) |
Figure S123. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D22V2.png)
P value = 7.18e-14 (Fisher's exact test), Q value = 7.5e-13
Table S124. Gene #22: 'amp_12q14.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 22(12Q14.1) MUTATED | 134 | 37 |
AMP PEAK 22(12Q14.1) WILD-TYPE | 437 | 475 |
Figure S124. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D22V3.png)
P value = 0.00811 (Fisher's exact test), Q value = 0.02
Table S125. Gene #22: 'amp_12q14.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 22(12Q14.1) MUTATED | 28 | 136 |
AMP PEAK 22(12Q14.1) WILD-TYPE | 230 | 631 |
Figure S125. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D22V5.png)
P value = 0.117 (Wilcoxon-test), Q value = 0.2
Table S126. Gene #22: 'amp_12q14.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 22(12Q14.1) MUTATED | 119 | 79.2 (15.5) |
AMP PEAK 22(12Q14.1) WILD-TYPE | 611 | 81.7 (14.5) |
Figure S126. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D22V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S127. Gene #22: 'amp_12q14.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 22(12Q14.1) MUTATED | 22 | 5 | 5 | 10 | 3 | 126 |
AMP PEAK 22(12Q14.1) WILD-TYPE | 172 | 23 | 124 | 179 | 15 | 399 |
Figure S127. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D22V7.png)
P value = 0.0336 (Fisher's exact test), Q value = 0.071
Table S128. Gene #22: 'amp_12q14.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 22(12Q14.1) MUTATED | 2 | 150 |
AMP PEAK 22(12Q14.1) WILD-TYPE | 42 | 769 |
Figure S128. Get High-res Image Gene #22: 'amp_12q14.1' versus Clinical Feature #9: 'ETHNICITY'
![](D22V9.png)
P value = 2.55e-10 (logrank test), Q value = 1.9e-09
Table S129. Gene #23: 'amp_12q15' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 23(12Q15) MUTATED | 110 | 89 | 0.2 - 84.3 (14.0) |
AMP PEAK 23(12Q15) WILD-TYPE | 969 | 502 | 0.0 - 211.2 (16.0) |
Figure S129. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #1: 'Time to Death'
![](D23V1.png)
P value = 4.78e-05 (Wilcoxon-test), Q value = 0.00017
Table S130. Gene #23: 'amp_12q15' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 23(12Q15) MUTATED | 110 | 56.6 (14.3) |
AMP PEAK 23(12Q15) WILD-TYPE | 972 | 50.1 (15.8) |
Figure S130. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D23V2.png)
P value = 1.49e-12 (Fisher's exact test), Q value = 1.4e-11
Table S131. Gene #23: 'amp_12q15' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 23(12Q15) MUTATED | 92 | 18 |
AMP PEAK 23(12Q15) WILD-TYPE | 479 | 494 |
Figure S131. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D23V3.png)
P value = 0.0442 (Fisher's exact test), Q value = 0.09
Table S132. Gene #23: 'amp_12q15' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 23(12Q15) MUTATED | 18 | 88 |
AMP PEAK 23(12Q15) WILD-TYPE | 240 | 679 |
Figure S132. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D23V5.png)
P value = 0.0364 (Wilcoxon-test), Q value = 0.076
Table S133. Gene #23: 'amp_12q15' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 23(12Q15) MUTATED | 86 | 78.5 (14.5) |
AMP PEAK 23(12Q15) WILD-TYPE | 644 | 81.7 (14.7) |
Figure S133. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D23V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S134. Gene #23: 'amp_12q15' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 23(12Q15) MUTATED | 8 | 3 | 2 | 8 | 2 | 87 |
AMP PEAK 23(12Q15) WILD-TYPE | 186 | 25 | 127 | 181 | 16 | 438 |
Figure S134. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D23V7.png)
P value = 0.0172 (Fisher's exact test), Q value = 0.039
Table S135. Gene #23: 'amp_12q15' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 23(12Q15) MUTATED | 0 | 96 |
AMP PEAK 23(12Q15) WILD-TYPE | 44 | 823 |
Figure S135. Get High-res Image Gene #23: 'amp_12q15' versus Clinical Feature #9: 'ETHNICITY'
![](D23V9.png)
P value = 0.0801 (Wilcoxon-test), Q value = 0.15
Table S136. Gene #24: 'amp_13q34' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 24(13Q34) MUTATED | 36 | 76.9 (15.8) |
AMP PEAK 24(13Q34) WILD-TYPE | 694 | 81.5 (14.6) |
Figure S136. Get High-res Image Gene #24: 'amp_13q34' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D24V6.png)
P value = 0.000792 (logrank test), Q value = 0.0025
Table S137. Gene #25: 'amp_14q32.33' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 25(14Q32.33) MUTATED | 44 | 34 | 0.4 - 72.9 (13.0) |
AMP PEAK 25(14Q32.33) WILD-TYPE | 1035 | 557 | 0.0 - 211.2 (15.8) |
Figure S137. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #1: 'Time to Death'
![](D25V1.png)
P value = 8.78e-06 (Wilcoxon-test), Q value = 3.9e-05
Table S138. Gene #25: 'amp_14q32.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 25(14Q32.33) MUTATED | 44 | 61.0 (14.9) |
AMP PEAK 25(14Q32.33) WILD-TYPE | 1038 | 50.3 (15.7) |
Figure S138. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D25V2.png)
P value = 7.54e-05 (Fisher's exact test), Q value = 0.00027
Table S139. Gene #25: 'amp_14q32.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 25(14Q32.33) MUTATED | 36 | 8 |
AMP PEAK 25(14Q32.33) WILD-TYPE | 535 | 504 |
Figure S139. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D25V3.png)
P value = 0.0644 (Fisher's exact test), Q value = 0.12
Table S140. Gene #25: 'amp_14q32.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 25(14Q32.33) MUTATED | 5 | 36 |
AMP PEAK 25(14Q32.33) WILD-TYPE | 253 | 731 |
Figure S140. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D25V5.png)
P value = 0.0844 (Wilcoxon-test), Q value = 0.16
Table S141. Gene #25: 'amp_14q32.33' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 25(14Q32.33) MUTATED | 33 | 76.7 (16.7) |
AMP PEAK 25(14Q32.33) WILD-TYPE | 697 | 81.5 (14.6) |
Figure S141. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D25V6.png)
P value = 0.00182 (Fisher's exact test), Q value = 0.0053
Table S142. Gene #25: 'amp_14q32.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 25(14Q32.33) MUTATED | 2 | 2 | 3 | 3 | 2 | 32 |
AMP PEAK 25(14Q32.33) WILD-TYPE | 192 | 26 | 126 | 186 | 16 | 493 |
Figure S142. Get High-res Image Gene #25: 'amp_14q32.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D25V7.png)
P value = 0.00322 (logrank test), Q value = 0.0089
Table S143. Gene #26: 'amp_17p13.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 26(17P13.2) MUTATED | 74 | 52 | 0.2 - 72.4 (14.5) |
AMP PEAK 26(17P13.2) WILD-TYPE | 1005 | 539 | 0.0 - 211.2 (15.8) |
Figure S143. Get High-res Image Gene #26: 'amp_17p13.2' versus Clinical Feature #1: 'Time to Death'
![](D26V1.png)
P value = 0.0107 (Wilcoxon-test), Q value = 0.026
Table S144. Gene #26: 'amp_17p13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 26(17P13.2) MUTATED | 74 | 55.0 (16.1) |
AMP PEAK 26(17P13.2) WILD-TYPE | 1008 | 50.5 (15.7) |
Figure S144. Get High-res Image Gene #26: 'amp_17p13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D26V2.png)
P value = 0.00377 (Fisher's exact test), Q value = 0.01
Table S145. Gene #26: 'amp_17p13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 26(17P13.2) MUTATED | 51 | 23 |
AMP PEAK 26(17P13.2) WILD-TYPE | 520 | 489 |
Figure S145. Get High-res Image Gene #26: 'amp_17p13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D26V3.png)
P value = 0.0664 (Fisher's exact test), Q value = 0.13
Table S146. Gene #26: 'amp_17p13.2' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
AMP PEAK 26(17P13.2) MUTATED | 23 | 51 |
AMP PEAK 26(17P13.2) WILD-TYPE | 429 | 580 |
Figure S146. Get High-res Image Gene #26: 'amp_17p13.2' versus Clinical Feature #4: 'GENDER'
![](D26V4.png)
P value = 0.0044 (Fisher's exact test), Q value = 0.012
Table S147. Gene #26: 'amp_17p13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 26(17P13.2) MUTATED | 10 | 4 | 1 | 12 | 1 | 46 |
AMP PEAK 26(17P13.2) WILD-TYPE | 184 | 24 | 128 | 177 | 17 | 479 |
Figure S147. Get High-res Image Gene #26: 'amp_17p13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D26V7.png)
P value = 9.1e-06 (logrank test), Q value = 3.9e-05
Table S148. Gene #27: 'amp_17q25.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 27(17Q25.1) MUTATED | 126 | 89 | 0.1 - 91.8 (13.6) |
AMP PEAK 27(17Q25.1) WILD-TYPE | 953 | 502 | 0.0 - 211.2 (16.0) |
Figure S148. Get High-res Image Gene #27: 'amp_17q25.1' versus Clinical Feature #1: 'Time to Death'
![](D27V1.png)
P value = 1.93e-05 (Wilcoxon-test), Q value = 7.3e-05
Table S149. Gene #27: 'amp_17q25.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 27(17Q25.1) MUTATED | 126 | 56.3 (14.9) |
AMP PEAK 27(17Q25.1) WILD-TYPE | 956 | 50.1 (15.8) |
Figure S149. Get High-res Image Gene #27: 'amp_17q25.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D27V2.png)
P value = 0.0017 (Fisher's exact test), Q value = 0.005
Table S150. Gene #27: 'amp_17q25.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 27(17Q25.1) MUTATED | 83 | 43 |
AMP PEAK 27(17Q25.1) WILD-TYPE | 488 | 469 |
Figure S150. Get High-res Image Gene #27: 'amp_17q25.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D27V3.png)
P value = 0.103 (Fisher's exact test), Q value = 0.18
Table S151. Gene #27: 'amp_17q25.1' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
AMP PEAK 27(17Q25.1) MUTATED | 44 | 82 |
AMP PEAK 27(17Q25.1) WILD-TYPE | 408 | 549 |
Figure S151. Get High-res Image Gene #27: 'amp_17q25.1' versus Clinical Feature #4: 'GENDER'
![](D27V4.png)
P value = 0.0224 (Fisher's exact test), Q value = 0.05
Table S152. Gene #27: 'amp_17q25.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 27(17Q25.1) MUTATED | 21 | 5 | 8 | 14 | 2 | 76 |
AMP PEAK 27(17Q25.1) WILD-TYPE | 173 | 23 | 121 | 175 | 16 | 449 |
Figure S152. Get High-res Image Gene #27: 'amp_17q25.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D27V7.png)
P value = 0.0101 (logrank test), Q value = 0.025
Table S153. Gene #28: 'amp_19p13.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 28(19P13.3) MUTATED | 370 | 229 | 0.0 - 172.8 (15.8) |
AMP PEAK 28(19P13.3) WILD-TYPE | 709 | 362 | 0.1 - 211.2 (15.3) |
Figure S153. Get High-res Image Gene #28: 'amp_19p13.3' versus Clinical Feature #1: 'Time to Death'
![](D28V1.png)
P value = 5.05e-05 (Wilcoxon-test), Q value = 0.00018
Table S154. Gene #28: 'amp_19p13.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 28(19P13.3) MUTATED | 371 | 53.4 (14.6) |
AMP PEAK 28(19P13.3) WILD-TYPE | 711 | 49.4 (16.2) |
Figure S154. Get High-res Image Gene #28: 'amp_19p13.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D28V2.png)
P value = 2.19e-09 (Fisher's exact test), Q value = 1.5e-08
Table S155. Gene #28: 'amp_19p13.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 28(19P13.3) MUTATED | 243 | 129 |
AMP PEAK 28(19P13.3) WILD-TYPE | 328 | 383 |
Figure S155. Get High-res Image Gene #28: 'amp_19p13.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D28V3.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S156. Gene #28: 'amp_19p13.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 28(19P13.3) MUTATED | 26 | 12 | 29 | 74 | 10 | 221 |
AMP PEAK 28(19P13.3) WILD-TYPE | 168 | 16 | 100 | 115 | 8 | 304 |
Figure S156. Get High-res Image Gene #28: 'amp_19p13.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D28V7.png)
P value = 0.000258 (logrank test), Q value = 0.00085
Table S157. Gene #29: 'amp_19p13.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 29(19P13.2) MUTATED | 365 | 230 | 0.1 - 169.8 (15.4) |
AMP PEAK 29(19P13.2) WILD-TYPE | 714 | 361 | 0.0 - 211.2 (15.9) |
Figure S157. Get High-res Image Gene #29: 'amp_19p13.2' versus Clinical Feature #1: 'Time to Death'
![](D29V1.png)
P value = 4.93e-07 (Wilcoxon-test), Q value = 2.8e-06
Table S158. Gene #29: 'amp_19p13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 29(19P13.2) MUTATED | 367 | 54.2 (14.4) |
AMP PEAK 29(19P13.2) WILD-TYPE | 715 | 49.0 (16.2) |
Figure S158. Get High-res Image Gene #29: 'amp_19p13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D29V2.png)
P value = 1.98e-11 (Fisher's exact test), Q value = 1.6e-10
Table S159. Gene #29: 'amp_19p13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 29(19P13.2) MUTATED | 246 | 122 |
AMP PEAK 29(19P13.2) WILD-TYPE | 325 | 390 |
Figure S159. Get High-res Image Gene #29: 'amp_19p13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D29V3.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S160. Gene #29: 'amp_19p13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 29(19P13.2) MUTATED | 24 | 11 | 25 | 73 | 10 | 225 |
AMP PEAK 29(19P13.2) WILD-TYPE | 170 | 17 | 104 | 116 | 8 | 300 |
Figure S160. Get High-res Image Gene #29: 'amp_19p13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D29V7.png)
P value = 0 (logrank test), Q value = 0
Table S161. Gene #30: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 30(19Q12) MUTATED | 244 | 190 | 0.0 - 92.7 (14.1) |
AMP PEAK 30(19Q12) WILD-TYPE | 835 | 401 | 0.1 - 211.2 (16.4) |
Figure S161. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #1: 'Time to Death'
![](D30V1.png)
P value = 4.86e-16 (Wilcoxon-test), Q value = 6.3e-15
Table S162. Gene #30: 'amp_19q12' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 30(19Q12) MUTATED | 245 | 57.9 (12.8) |
AMP PEAK 30(19Q12) WILD-TYPE | 837 | 48.7 (16.0) |
Figure S162. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D30V2.png)
P value = 3.12e-38 (Fisher's exact test), Q value = 5.8e-37
Table S163. Gene #30: 'amp_19q12' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 30(19Q12) MUTATED | 214 | 31 |
AMP PEAK 30(19Q12) WILD-TYPE | 357 | 481 |
Figure S163. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D30V3.png)
P value = 6.89e-08 (Fisher's exact test), Q value = 4.2e-07
Table S164. Gene #30: 'amp_19q12' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 30(19Q12) MUTATED | 28 | 202 |
AMP PEAK 30(19Q12) WILD-TYPE | 230 | 565 |
Figure S164. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D30V5.png)
P value = 9.53e-05 (Wilcoxon-test), Q value = 0.00033
Table S165. Gene #30: 'amp_19q12' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 30(19Q12) MUTATED | 166 | 77.9 (14.7) |
AMP PEAK 30(19Q12) WILD-TYPE | 564 | 82.3 (14.6) |
Figure S165. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D30V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S166. Gene #30: 'amp_19q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 30(19Q12) MUTATED | 16 | 13 | 9 | 6 | 8 | 193 |
AMP PEAK 30(19Q12) WILD-TYPE | 178 | 15 | 120 | 183 | 10 | 332 |
Figure S166. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D30V7.png)
P value = 0.0403 (Fisher's exact test), Q value = 0.083
Table S167. Gene #30: 'amp_19q12' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 30(19Q12) MUTATED | 0 | 8 | 23 | 206 |
AMP PEAK 30(19Q12) WILD-TYPE | 1 | 13 | 48 | 751 |
Figure S167. Get High-res Image Gene #30: 'amp_19q12' versus Clinical Feature #8: 'RACE'
![](D30V8.png)
P value = 0 (logrank test), Q value = 0
Table S168. Gene #31: 'amp_19q13.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 31(19Q13.2) MUTATED | 229 | 175 | 0.1 - 92.7 (14.2) |
AMP PEAK 31(19Q13.2) WILD-TYPE | 850 | 416 | 0.0 - 211.2 (16.3) |
Figure S168. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #1: 'Time to Death'
![](D31V1.png)
P value = 1.81e-15 (Wilcoxon-test), Q value = 2.1e-14
Table S169. Gene #31: 'amp_19q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 31(19Q13.2) MUTATED | 230 | 58.0 (12.4) |
AMP PEAK 31(19Q13.2) WILD-TYPE | 852 | 48.8 (16.0) |
Figure S169. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D31V2.png)
P value = 9.95e-34 (Fisher's exact test), Q value = 1.7e-32
Table S170. Gene #31: 'amp_19q13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 31(19Q13.2) MUTATED | 199 | 31 |
AMP PEAK 31(19Q13.2) WILD-TYPE | 372 | 481 |
Figure S170. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D31V3.png)
P value = 5.99e-07 (Fisher's exact test), Q value = 3.4e-06
Table S171. Gene #31: 'amp_19q13.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 31(19Q13.2) MUTATED | 27 | 188 |
AMP PEAK 31(19Q13.2) WILD-TYPE | 231 | 579 |
Figure S171. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D31V5.png)
P value = 0.000304 (Wilcoxon-test), Q value = 0.00099
Table S172. Gene #31: 'amp_19q13.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 31(19Q13.2) MUTATED | 160 | 78.2 (14.6) |
AMP PEAK 31(19Q13.2) WILD-TYPE | 570 | 82.2 (14.6) |
Figure S172. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D31V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S173. Gene #31: 'amp_19q13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 31(19Q13.2) MUTATED | 18 | 12 | 7 | 6 | 6 | 181 |
AMP PEAK 31(19Q13.2) WILD-TYPE | 176 | 16 | 122 | 183 | 12 | 344 |
Figure S173. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D31V7.png)
P value = 0.0337 (Fisher's exact test), Q value = 0.071
Table S174. Gene #31: 'amp_19q13.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
AMP PEAK 31(19Q13.2) MUTATED | 0 | 7 | 23 | 193 |
AMP PEAK 31(19Q13.2) WILD-TYPE | 1 | 14 | 48 | 764 |
Figure S174. Get High-res Image Gene #31: 'amp_19q13.2' versus Clinical Feature #8: 'RACE'
![](D31V8.png)
P value = 0.000448 (logrank test), Q value = 0.0014
Table S175. Gene #32: 'amp_xp11.21' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
AMP PEAK 32(XP11.21) MUTATED | 104 | 41 | 0.1 - 145.1 (19.5) |
AMP PEAK 32(XP11.21) WILD-TYPE | 975 | 550 | 0.0 - 211.2 (15.3) |
Figure S175. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #1: 'Time to Death'
![](D32V1.png)
P value = 3.21e-06 (Wilcoxon-test), Q value = 1.7e-05
Table S176. Gene #32: 'amp_xp11.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
AMP PEAK 32(XP11.21) MUTATED | 104 | 43.9 (15.7) |
AMP PEAK 32(XP11.21) WILD-TYPE | 978 | 51.5 (15.6) |
Figure S176. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D32V2.png)
P value = 1.89e-05 (Fisher's exact test), Q value = 7.2e-05
Table S177. Gene #32: 'amp_xp11.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
AMP PEAK 32(XP11.21) MUTATED | 34 | 70 |
AMP PEAK 32(XP11.21) WILD-TYPE | 537 | 442 |
Figure S177. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D32V3.png)
P value = 0.0284 (Fisher's exact test), Q value = 0.061
Table S178. Gene #32: 'amp_xp11.21' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
AMP PEAK 32(XP11.21) MUTATED | 54 | 50 |
AMP PEAK 32(XP11.21) WILD-TYPE | 398 | 581 |
Figure S178. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #4: 'GENDER'
![](D32V4.png)
P value = 0.00971 (Fisher's exact test), Q value = 0.024
Table S179. Gene #32: 'amp_xp11.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
AMP PEAK 32(XP11.21) MUTATED | 14 | 84 |
AMP PEAK 32(XP11.21) WILD-TYPE | 244 | 683 |
Figure S179. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D32V5.png)
P value = 0.0254 (Wilcoxon-test), Q value = 0.056
Table S180. Gene #32: 'amp_xp11.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
AMP PEAK 32(XP11.21) MUTATED | 67 | 84.3 (15.1) |
AMP PEAK 32(XP11.21) WILD-TYPE | 663 | 81.0 (14.6) |
Figure S180. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D32V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S181. Gene #32: 'amp_xp11.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
AMP PEAK 32(XP11.21) MUTATED | 44 | 3 | 17 | 9 | 2 | 29 |
AMP PEAK 32(XP11.21) WILD-TYPE | 150 | 25 | 112 | 180 | 16 | 496 |
Figure S181. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D32V7.png)
P value = 0.0304 (Fisher's exact test), Q value = 0.065
Table S182. Gene #32: 'amp_xp11.21' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
AMP PEAK 32(XP11.21) MUTATED | 9 | 84 |
AMP PEAK 32(XP11.21) WILD-TYPE | 35 | 835 |
Figure S182. Get High-res Image Gene #32: 'amp_xp11.21' versus Clinical Feature #9: 'ETHNICITY'
![](D32V9.png)
P value = 5.51e-09 (logrank test), Q value = 3.5e-08
Table S183. Gene #33: 'del_1p36.32' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 1(1P36.32) MUTATED | 312 | 127 | 0.1 - 182.3 (17.2) |
DEL PEAK 1(1P36.32) WILD-TYPE | 767 | 464 | 0.0 - 211.2 (14.9) |
Figure S183. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #1: 'Time to Death'
![](D33V1.png)
P value = 1.26e-14 (Fisher's exact test), Q value = 1.4e-13
Table S184. Gene #33: 'del_1p36.32' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 1(1P36.32) MUTATED | 108 | 206 |
DEL PEAK 1(1P36.32) WILD-TYPE | 463 | 306 |
Figure S184. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D33V3.png)
P value = 5.48e-08 (Fisher's exact test), Q value = 3.3e-07
Table S185. Gene #33: 'del_1p36.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 1(1P36.32) MUTATED | 110 | 187 |
DEL PEAK 1(1P36.32) WILD-TYPE | 148 | 580 |
Figure S185. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D33V5.png)
P value = 0.0215 (Wilcoxon-test), Q value = 0.048
Table S186. Gene #33: 'del_1p36.32' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 1(1P36.32) MUTATED | 215 | 82.7 (15.9) |
DEL PEAK 1(1P36.32) WILD-TYPE | 515 | 80.7 (14.2) |
Figure S186. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D33V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S187. Gene #33: 'del_1p36.32' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 1(1P36.32) MUTATED | 22 | 1 | 46 | 138 | 4 | 103 |
DEL PEAK 1(1P36.32) WILD-TYPE | 172 | 27 | 83 | 51 | 14 | 422 |
Figure S187. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D33V7.png)
P value = 0.022 (Fisher's exact test), Q value = 0.049
Table S188. Gene #33: 'del_1p36.32' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 1(1P36.32) MUTATED | 1 | 10 | 14 | 281 |
DEL PEAK 1(1P36.32) WILD-TYPE | 0 | 11 | 57 | 676 |
Figure S188. Get High-res Image Gene #33: 'del_1p36.32' versus Clinical Feature #8: 'RACE'
![](D33V8.png)
P value = 1.37e-05 (logrank test), Q value = 5.3e-05
Table S189. Gene #34: 'del_1p36.23' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 2(1P36.23) MUTATED | 342 | 154 | 0.1 - 182.3 (16.5) |
DEL PEAK 2(1P36.23) WILD-TYPE | 737 | 437 | 0.0 - 211.2 (15.0) |
Figure S189. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #1: 'Time to Death'
![](D34V1.png)
P value = 1.23e-10 (Fisher's exact test), Q value = 9.7e-10
Table S190. Gene #34: 'del_1p36.23' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 2(1P36.23) MUTATED | 132 | 212 |
DEL PEAK 2(1P36.23) WILD-TYPE | 439 | 300 |
Figure S190. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D34V3.png)
P value = 4.42e-07 (Fisher's exact test), Q value = 2.6e-06
Table S191. Gene #34: 'del_1p36.23' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 2(1P36.23) MUTATED | 116 | 211 |
DEL PEAK 2(1P36.23) WILD-TYPE | 142 | 556 |
Figure S191. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D34V5.png)
P value = 0.00254 (Wilcoxon-test), Q value = 0.0073
Table S192. Gene #34: 'del_1p36.23' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 2(1P36.23) MUTATED | 234 | 83.1 (16.0) |
DEL PEAK 2(1P36.23) WILD-TYPE | 496 | 80.4 (14.0) |
Figure S192. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D34V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S193. Gene #34: 'del_1p36.23' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 2(1P36.23) MUTATED | 24 | 4 | 48 | 140 | 3 | 125 |
DEL PEAK 2(1P36.23) WILD-TYPE | 170 | 24 | 81 | 49 | 15 | 400 |
Figure S193. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D34V7.png)
P value = 0.046 (Fisher's exact test), Q value = 0.093
Table S194. Gene #34: 'del_1p36.23' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 2(1P36.23) MUTATED | 1 | 11 | 18 | 304 |
DEL PEAK 2(1P36.23) WILD-TYPE | 0 | 10 | 53 | 653 |
Figure S194. Get High-res Image Gene #34: 'del_1p36.23' versus Clinical Feature #8: 'RACE'
![](D34V8.png)
P value = 9.31e-14 (logrank test), Q value = 9.2e-13
Table S195. Gene #35: 'del_1p32.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 3(1P32.3) MUTATED | 254 | 81 | 0.1 - 182.3 (17.1) |
DEL PEAK 3(1P32.3) WILD-TYPE | 825 | 510 | 0.0 - 211.2 (15.1) |
Figure S195. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #1: 'Time to Death'
![](D35V1.png)
P value = 1.69e-27 (Fisher's exact test), Q value = 2.7e-26
Table S196. Gene #35: 'del_1p32.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 3(1P32.3) MUTATED | 60 | 196 |
DEL PEAK 3(1P32.3) WILD-TYPE | 511 | 316 |
Figure S196. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D35V3.png)
P value = 3.12e-13 (Fisher's exact test), Q value = 3e-12
Table S197. Gene #35: 'del_1p32.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 3(1P32.3) MUTATED | 105 | 134 |
DEL PEAK 3(1P32.3) WILD-TYPE | 153 | 633 |
Figure S197. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D35V5.png)
P value = 0.00142 (Wilcoxon-test), Q value = 0.0042
Table S198. Gene #35: 'del_1p32.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 3(1P32.3) MUTATED | 161 | 84.5 (13.4) |
DEL PEAK 3(1P32.3) WILD-TYPE | 569 | 80.4 (14.9) |
Figure S198. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D35V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S199. Gene #35: 'del_1p32.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 3(1P32.3) MUTATED | 16 | 1 | 42 | 138 | 2 | 57 |
DEL PEAK 3(1P32.3) WILD-TYPE | 178 | 27 | 87 | 51 | 16 | 468 |
Figure S199. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D35V7.png)
P value = 0.0379 (Fisher's exact test), Q value = 0.078
Table S200. Gene #35: 'del_1p32.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 3(1P32.3) MUTATED | 1 | 7 | 10 | 230 |
DEL PEAK 3(1P32.3) WILD-TYPE | 0 | 14 | 61 | 727 |
Figure S200. Get High-res Image Gene #35: 'del_1p32.3' versus Clinical Feature #8: 'RACE'
![](D35V8.png)
P value = 0 (logrank test), Q value = 0
Table S201. Gene #36: 'del_1p22.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 4(1P22.1) MUTATED | 231 | 66 | 0.1 - 182.3 (20.1) |
DEL PEAK 4(1P22.1) WILD-TYPE | 848 | 525 | 0.0 - 211.2 (14.9) |
Figure S201. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #1: 'Time to Death'
![](D36V1.png)
P value = 0.00387 (Wilcoxon-test), Q value = 0.011
Table S202. Gene #36: 'del_1p22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 4(1P22.1) MUTATED | 232 | 48.3 (13.9) |
DEL PEAK 4(1P22.1) WILD-TYPE | 850 | 51.5 (16.2) |
Figure S202. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D36V2.png)
P value = 2.27e-30 (Fisher's exact test), Q value = 3.8e-29
Table S203. Gene #36: 'del_1p22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 4(1P22.1) MUTATED | 47 | 186 |
DEL PEAK 4(1P22.1) WILD-TYPE | 524 | 326 |
Figure S203. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D36V3.png)
P value = 2.08e-14 (Fisher's exact test), Q value = 2.3e-13
Table S204. Gene #36: 'del_1p22.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 4(1P22.1) MUTATED | 100 | 117 |
DEL PEAK 4(1P22.1) WILD-TYPE | 158 | 650 |
Figure S204. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D36V5.png)
P value = 0.000136 (Wilcoxon-test), Q value = 0.00047
Table S205. Gene #36: 'del_1p22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 4(1P22.1) MUTATED | 148 | 84.9 (14.5) |
DEL PEAK 4(1P22.1) WILD-TYPE | 582 | 80.4 (14.6) |
Figure S205. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D36V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S206. Gene #36: 'del_1p22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 4(1P22.1) MUTATED | 11 | 1 | 39 | 136 | 4 | 42 |
DEL PEAK 4(1P22.1) WILD-TYPE | 183 | 27 | 90 | 53 | 14 | 483 |
Figure S206. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D36V7.png)
P value = 0.139 (Fisher's exact test), Q value = 0.24
Table S207. Gene #36: 'del_1p22.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 4(1P22.1) MUTATED | 14 | 202 |
DEL PEAK 4(1P22.1) WILD-TYPE | 30 | 717 |
Figure S207. Get High-res Image Gene #36: 'del_1p22.1' versus Clinical Feature #9: 'ETHNICITY'
![](D36V9.png)
P value = 0.0283 (logrank test), Q value = 0.061
Table S208. Gene #37: 'del_1q42.11' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 5(1Q42.11) MUTATED | 77 | 50 | 0.1 - 146.1 (12.6) |
DEL PEAK 5(1Q42.11) WILD-TYPE | 1002 | 541 | 0.0 - 211.2 (16.0) |
Figure S208. Get High-res Image Gene #37: 'del_1q42.11' versus Clinical Feature #1: 'Time to Death'
![](D37V1.png)
P value = 0.0334 (Wilcoxon-test), Q value = 0.071
Table S209. Gene #37: 'del_1q42.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 5(1Q42.11) MUTATED | 77 | 54.6 (15.0) |
DEL PEAK 5(1Q42.11) WILD-TYPE | 1005 | 50.5 (15.8) |
Figure S209. Get High-res Image Gene #37: 'del_1q42.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D37V2.png)
P value = 0.0576 (Fisher's exact test), Q value = 0.11
Table S210. Gene #37: 'del_1q42.11' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 5(1Q42.11) MUTATED | 49 | 28 |
DEL PEAK 5(1Q42.11) WILD-TYPE | 522 | 484 |
Figure S210. Get High-res Image Gene #37: 'del_1q42.11' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D37V3.png)
P value = 0.0152 (Wilcoxon-test), Q value = 0.035
Table S211. Gene #37: 'del_1q42.11' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 5(1Q42.11) MUTATED | 61 | 75.9 (18.0) |
DEL PEAK 5(1Q42.11) WILD-TYPE | 669 | 81.8 (14.3) |
Figure S211. Get High-res Image Gene #37: 'del_1q42.11' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D37V6.png)
P value = 0.00412 (logrank test), Q value = 0.011
Table S212. Gene #39: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 7(2Q22.1) MUTATED | 68 | 51 | 1.3 - 117.4 (15.2) |
DEL PEAK 7(2Q22.1) WILD-TYPE | 1011 | 540 | 0.0 - 211.2 (15.8) |
Figure S212. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #1: 'Time to Death'
![](D39V1.png)
P value = 0.0169 (Wilcoxon-test), Q value = 0.039
Table S213. Gene #39: 'del_2q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 7(2Q22.1) MUTATED | 68 | 55.0 (16.8) |
DEL PEAK 7(2Q22.1) WILD-TYPE | 1014 | 50.5 (15.7) |
Figure S213. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D39V2.png)
P value = 0.00558 (Fisher's exact test), Q value = 0.015
Table S214. Gene #39: 'del_2q22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 7(2Q22.1) MUTATED | 47 | 21 |
DEL PEAK 7(2Q22.1) WILD-TYPE | 524 | 491 |
Figure S214. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D39V3.png)
P value = 0.0771 (Wilcoxon-test), Q value = 0.14
Table S215. Gene #39: 'del_2q22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 7(2Q22.1) MUTATED | 48 | 78.3 (13.1) |
DEL PEAK 7(2Q22.1) WILD-TYPE | 682 | 81.5 (14.8) |
Figure S215. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D39V6.png)
P value = 0.00396 (Fisher's exact test), Q value = 0.011
Table S216. Gene #39: 'del_2q22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 7(2Q22.1) MUTATED | 13 | 5 | 3 | 5 | 2 | 40 |
DEL PEAK 7(2Q22.1) WILD-TYPE | 181 | 23 | 126 | 184 | 16 | 485 |
Figure S216. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D39V7.png)
P value = 0.105 (Fisher's exact test), Q value = 0.19
Table S217. Gene #39: 'del_2q22.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 7(2Q22.1) MUTATED | 0 | 60 |
DEL PEAK 7(2Q22.1) WILD-TYPE | 44 | 859 |
Figure S217. Get High-res Image Gene #39: 'del_2q22.1' versus Clinical Feature #9: 'ETHNICITY'
![](D39V9.png)
P value = 0.0283 (Wilcoxon-test), Q value = 0.061
Table S218. Gene #40: 'del_2q37.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 8(2Q37.1) MUTATED | 121 | 47.9 (17.0) |
DEL PEAK 8(2Q37.1) WILD-TYPE | 961 | 51.1 (15.6) |
Figure S218. Get High-res Image Gene #40: 'del_2q37.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D40V2.png)
P value = 0.1 (Fisher's exact test), Q value = 0.18
Table S219. Gene #40: 'del_2q37.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 8(2Q37.1) MUTATED | 55 | 66 |
DEL PEAK 8(2Q37.1) WILD-TYPE | 516 | 446 |
Figure S219. Get High-res Image Gene #40: 'del_2q37.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D40V3.png)
P value = 0.00613 (Fisher's exact test), Q value = 0.016
Table S220. Gene #40: 'del_2q37.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 8(2Q37.1) MUTATED | 34 | 3 | 20 | 12 | 1 | 51 |
DEL PEAK 8(2Q37.1) WILD-TYPE | 160 | 25 | 109 | 177 | 17 | 474 |
Figure S220. Get High-res Image Gene #40: 'del_2q37.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D40V7.png)
P value = 0.0012 (Fisher's exact test), Q value = 0.0037
Table S221. Gene #41: 'del_3p21.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 9(3P21.31) MUTATED | 13 | 91 |
DEL PEAK 9(3P21.31) WILD-TYPE | 245 | 676 |
Figure S221. Get High-res Image Gene #41: 'del_3p21.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D41V5.png)
P value = 0.114 (logrank test), Q value = 0.2
Table S222. Gene #42: 'del_3q13.31' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 10(3Q13.31) MUTATED | 95 | 63 | 0.1 - 117.4 (15.9) |
DEL PEAK 10(3Q13.31) WILD-TYPE | 984 | 528 | 0.0 - 211.2 (15.4) |
Figure S222. Get High-res Image Gene #42: 'del_3q13.31' versus Clinical Feature #1: 'Time to Death'
![](D42V1.png)
P value = 0.0722 (Fisher's exact test), Q value = 0.14
Table S223. Gene #42: 'del_3q13.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 10(3Q13.31) MUTATED | 15 | 73 |
DEL PEAK 10(3Q13.31) WILD-TYPE | 243 | 694 |
Figure S223. Get High-res Image Gene #42: 'del_3q13.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D42V5.png)
P value = 3.46e-05 (logrank test), Q value = 0.00013
Table S224. Gene #44: 'del_4q34.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 12(4Q34.3) MUTATED | 230 | 101 | 0.1 - 156.2 (19.8) |
DEL PEAK 12(4Q34.3) WILD-TYPE | 849 | 490 | 0.0 - 211.2 (14.9) |
Figure S224. Get High-res Image Gene #44: 'del_4q34.3' versus Clinical Feature #1: 'Time to Death'
![](D44V1.png)
P value = 0.0122 (Wilcoxon-test), Q value = 0.029
Table S225. Gene #44: 'del_4q34.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 12(4Q34.3) MUTATED | 230 | 48.5 (14.5) |
DEL PEAK 12(4Q34.3) WILD-TYPE | 852 | 51.4 (16.1) |
Figure S225. Get High-res Image Gene #44: 'del_4q34.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D44V2.png)
P value = 1.5e-05 (Fisher's exact test), Q value = 5.8e-05
Table S226. Gene #44: 'del_4q34.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 12(4Q34.3) MUTATED | 92 | 138 |
DEL PEAK 12(4Q34.3) WILD-TYPE | 479 | 374 |
Figure S226. Get High-res Image Gene #44: 'del_4q34.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D44V3.png)
P value = 0.114 (Fisher's exact test), Q value = 0.2
Table S227. Gene #44: 'del_4q34.3' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 12(4Q34.3) MUTATED | 85 | 145 |
DEL PEAK 12(4Q34.3) WILD-TYPE | 367 | 486 |
Figure S227. Get High-res Image Gene #44: 'del_4q34.3' versus Clinical Feature #4: 'GENDER'
![](D44V4.png)
P value = 0.00123 (Fisher's exact test), Q value = 0.0037
Table S228. Gene #44: 'del_4q34.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 12(4Q34.3) MUTATED | 49 | 5 | 36 | 53 | 2 | 85 |
DEL PEAK 12(4Q34.3) WILD-TYPE | 145 | 23 | 93 | 136 | 16 | 440 |
Figure S228. Get High-res Image Gene #44: 'del_4q34.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D44V7.png)
P value = 0.000375 (Fisher's exact test), Q value = 0.0012
Table S229. Gene #45: 'del_5p15.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 13(5P15.33) MUTATED | 11 | 88 |
DEL PEAK 13(5P15.33) WILD-TYPE | 247 | 679 |
Figure S229. Get High-res Image Gene #45: 'del_5p15.33' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D45V5.png)
P value = 0.0255 (Fisher's exact test), Q value = 0.056
Table S230. Gene #45: 'del_5p15.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 13(5P15.33) MUTATED | 23 | 3 | 19 | 8 | 1 | 52 |
DEL PEAK 13(5P15.33) WILD-TYPE | 171 | 25 | 110 | 181 | 17 | 473 |
Figure S230. Get High-res Image Gene #45: 'del_5p15.33' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D45V7.png)
P value = 0.0929 (Wilcoxon-test), Q value = 0.17
Table S231. Gene #46: 'del_5q34' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 14(5Q34) MUTATED | 132 | 48.5 (17.7) |
DEL PEAK 14(5Q34) WILD-TYPE | 950 | 51.1 (15.5) |
Figure S231. Get High-res Image Gene #46: 'del_5q34' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D46V2.png)
P value = 0.00179 (Fisher's exact test), Q value = 0.0053
Table S232. Gene #46: 'del_5q34' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 14(5Q34) MUTATED | 17 | 106 |
DEL PEAK 14(5Q34) WILD-TYPE | 241 | 661 |
Figure S232. Get High-res Image Gene #46: 'del_5q34' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D46V5.png)
P value = 0.00016 (Fisher's exact test), Q value = 0.00054
Table S233. Gene #46: 'del_5q34' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 14(5Q34) MUTATED | 40 | 6 | 13 | 10 | 1 | 62 |
DEL PEAK 14(5Q34) WILD-TYPE | 154 | 22 | 116 | 179 | 17 | 463 |
Figure S233. Get High-res Image Gene #46: 'del_5q34' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D46V7.png)
P value = 1.65e-07 (logrank test), Q value = 9.8e-07
Table S234. Gene #47: 'del_6p25.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 15(6P25.3) MUTATED | 137 | 95 | 0.1 - 145.1 (10.8) |
DEL PEAK 15(6P25.3) WILD-TYPE | 942 | 496 | 0.0 - 211.2 (16.3) |
Figure S234. Get High-res Image Gene #47: 'del_6p25.3' versus Clinical Feature #1: 'Time to Death'
![](D47V1.png)
P value = 0.0347 (Wilcoxon-test), Q value = 0.073
Table S235. Gene #47: 'del_6p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 15(6P25.3) MUTATED | 138 | 53.3 (15.9) |
DEL PEAK 15(6P25.3) WILD-TYPE | 944 | 50.4 (15.7) |
Figure S235. Get High-res Image Gene #47: 'del_6p25.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D47V2.png)
P value = 0.00607 (Fisher's exact test), Q value = 0.016
Table S236. Gene #47: 'del_6p25.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 15(6P25.3) MUTATED | 88 | 50 |
DEL PEAK 15(6P25.3) WILD-TYPE | 483 | 462 |
Figure S236. Get High-res Image Gene #47: 'del_6p25.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D47V3.png)
P value = 0.131 (Wilcoxon-test), Q value = 0.23
Table S237. Gene #47: 'del_6p25.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 15(6P25.3) MUTATED | 99 | 79.7 (13.9) |
DEL PEAK 15(6P25.3) WILD-TYPE | 631 | 81.5 (14.8) |
Figure S237. Get High-res Image Gene #47: 'del_6p25.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D47V6.png)
P value = 0.0577 (Fisher's exact test), Q value = 0.11
Table S238. Gene #47: 'del_6p25.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 15(6P25.3) MUTATED | 24 | 3 | 10 | 16 | 2 | 83 |
DEL PEAK 15(6P25.3) WILD-TYPE | 170 | 25 | 119 | 173 | 16 | 442 |
Figure S238. Get High-res Image Gene #47: 'del_6p25.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D47V7.png)
P value = 9.96e-12 (logrank test), Q value = 8.6e-11
Table S239. Gene #48: 'del_6q22.31' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 16(6Q22.31) MUTATED | 233 | 161 | 0.1 - 117.4 (12.6) |
DEL PEAK 16(6Q22.31) WILD-TYPE | 846 | 430 | 0.0 - 211.2 (16.8) |
Figure S239. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #1: 'Time to Death'
![](D48V1.png)
P value = 4.01e-05 (Wilcoxon-test), Q value = 0.00015
Table S240. Gene #48: 'del_6q22.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 16(6Q22.31) MUTATED | 234 | 54.6 (15.4) |
DEL PEAK 16(6Q22.31) WILD-TYPE | 848 | 49.7 (15.7) |
Figure S240. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D48V2.png)
P value = 6.44e-07 (Fisher's exact test), Q value = 3.6e-06
Table S241. Gene #48: 'del_6q22.31' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 16(6Q22.31) MUTATED | 157 | 77 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 414 | 435 |
Figure S241. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D48V3.png)
P value = 0.0995 (Fisher's exact test), Q value = 0.18
Table S242. Gene #48: 'del_6q22.31' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 16(6Q22.31) MUTATED | 109 | 125 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 343 | 506 |
Figure S242. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #4: 'GENDER'
![](D48V4.png)
P value = 0.0351 (Fisher's exact test), Q value = 0.074
Table S243. Gene #48: 'del_6q22.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 16(6Q22.31) MUTATED | 43 | 176 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 215 | 591 |
Figure S243. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D48V5.png)
P value = 0.00692 (Wilcoxon-test), Q value = 0.018
Table S244. Gene #48: 'del_6q22.31' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 16(6Q22.31) MUTATED | 169 | 78.9 (14.8) |
DEL PEAK 16(6Q22.31) WILD-TYPE | 561 | 82.0 (14.6) |
Figure S244. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D48V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S245. Gene #48: 'del_6q22.31' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 16(6Q22.31) MUTATED | 47 | 6 | 11 | 19 | 7 | 144 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 147 | 22 | 118 | 170 | 11 | 381 |
Figure S245. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D48V7.png)
P value = 0.0988 (Fisher's exact test), Q value = 0.18
Table S246. Gene #48: 'del_6q22.31' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 16(6Q22.31) MUTATED | 1 | 6 | 20 | 200 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 0 | 15 | 51 | 757 |
Figure S246. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #8: 'RACE'
![](D48V8.png)
P value = 0.13 (Fisher's exact test), Q value = 0.22
Table S247. Gene #48: 'del_6q22.31' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 16(6Q22.31) MUTATED | 5 | 199 |
DEL PEAK 16(6Q22.31) WILD-TYPE | 39 | 720 |
Figure S247. Get High-res Image Gene #48: 'del_6q22.31' versus Clinical Feature #9: 'ETHNICITY'
![](D48V9.png)
P value = 1.63e-11 (logrank test), Q value = 1.4e-10
Table S248. Gene #49: 'del_6q26' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 17(6Q26) MUTATED | 258 | 178 | 0.0 - 145.1 (13.2) |
DEL PEAK 17(6Q26) WILD-TYPE | 821 | 413 | 0.1 - 211.2 (16.8) |
Figure S248. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #1: 'Time to Death'
![](D49V1.png)
P value = 0.000142 (Wilcoxon-test), Q value = 0.00049
Table S249. Gene #49: 'del_6q26' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 17(6Q26) MUTATED | 259 | 53.9 (14.9) |
DEL PEAK 17(6Q26) WILD-TYPE | 823 | 49.8 (15.9) |
Figure S249. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D49V2.png)
P value = 2.65e-09 (Fisher's exact test), Q value = 1.8e-08
Table S250. Gene #49: 'del_6q26' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 17(6Q26) MUTATED | 178 | 81 |
DEL PEAK 17(6Q26) WILD-TYPE | 393 | 431 |
Figure S250. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D49V3.png)
P value = 0.00225 (Fisher's exact test), Q value = 0.0065
Table S251. Gene #49: 'del_6q26' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 17(6Q26) MUTATED | 43 | 199 |
DEL PEAK 17(6Q26) WILD-TYPE | 215 | 568 |
Figure S251. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D49V5.png)
P value = 0.00312 (Wilcoxon-test), Q value = 0.0087
Table S252. Gene #49: 'del_6q26' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 17(6Q26) MUTATED | 186 | 79.0 (14.4) |
DEL PEAK 17(6Q26) WILD-TYPE | 544 | 82.1 (14.7) |
Figure S252. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D49V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S253. Gene #49: 'del_6q26' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 17(6Q26) MUTATED | 48 | 7 | 12 | 21 | 9 | 162 |
DEL PEAK 17(6Q26) WILD-TYPE | 146 | 21 | 117 | 168 | 9 | 363 |
Figure S253. Get High-res Image Gene #49: 'del_6q26' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D49V7.png)
P value = 0.000161 (logrank test), Q value = 0.00054
Table S254. Gene #50: 'del_8p23.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 18(8P23.2) MUTATED | 87 | 59 | 0.1 - 120.6 (12.7) |
DEL PEAK 18(8P23.2) WILD-TYPE | 992 | 532 | 0.0 - 211.2 (16.0) |
Figure S254. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #1: 'Time to Death'
![](D50V1.png)
P value = 6.13e-05 (Wilcoxon-test), Q value = 0.00022
Table S255. Gene #50: 'del_8p23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 18(8P23.2) MUTATED | 88 | 57.1 (14.5) |
DEL PEAK 18(8P23.2) WILD-TYPE | 994 | 50.2 (15.8) |
Figure S255. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D50V2.png)
P value = 1.07e-05 (Fisher's exact test), Q value = 4.2e-05
Table S256. Gene #50: 'del_8p23.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 18(8P23.2) MUTATED | 66 | 22 |
DEL PEAK 18(8P23.2) WILD-TYPE | 505 | 490 |
Figure S256. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D50V3.png)
P value = 0.0111 (Fisher's exact test), Q value = 0.027
Table S257. Gene #50: 'del_8p23.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 18(8P23.2) MUTATED | 11 | 71 |
DEL PEAK 18(8P23.2) WILD-TYPE | 247 | 696 |
Figure S257. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D50V5.png)
P value = 0.00012 (Fisher's exact test), Q value = 0.00041
Table S258. Gene #50: 'del_8p23.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 18(8P23.2) MUTATED | 13 | 3 | 5 | 4 | 1 | 62 |
DEL PEAK 18(8P23.2) WILD-TYPE | 181 | 25 | 124 | 185 | 17 | 463 |
Figure S258. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D50V7.png)
P value = 0.0141 (Fisher's exact test), Q value = 0.033
Table S259. Gene #50: 'del_8p23.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 18(8P23.2) MUTATED | 0 | 6 | 6 | 72 |
DEL PEAK 18(8P23.2) WILD-TYPE | 1 | 15 | 65 | 885 |
Figure S259. Get High-res Image Gene #50: 'del_8p23.2' versus Clinical Feature #8: 'RACE'
![](D50V8.png)
P value = 0.0126 (logrank test), Q value = 0.03
Table S260. Gene #51: 'del_8q24.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 19(8Q24.3) MUTATED | 78 | 49 | 0.2 - 82.6 (14.3) |
DEL PEAK 19(8Q24.3) WILD-TYPE | 1001 | 542 | 0.0 - 211.2 (15.9) |
Figure S260. Get High-res Image Gene #51: 'del_8q24.3' versus Clinical Feature #1: 'Time to Death'
![](D51V1.png)
P value = 0.0248 (Fisher's exact test), Q value = 0.055
Table S261. Gene #51: 'del_8q24.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 19(8Q24.3) MUTATED | 51 | 27 |
DEL PEAK 19(8Q24.3) WILD-TYPE | 520 | 485 |
Figure S261. Get High-res Image Gene #51: 'del_8q24.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D51V3.png)
P value = 0.0127 (Fisher's exact test), Q value = 0.03
Table S262. Gene #51: 'del_8q24.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 19(8Q24.3) MUTATED | 10 | 65 |
DEL PEAK 19(8Q24.3) WILD-TYPE | 248 | 702 |
Figure S262. Get High-res Image Gene #51: 'del_8q24.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D51V5.png)
P value = 0.0845 (Fisher's exact test), Q value = 0.16
Table S263. Gene #51: 'del_8q24.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 19(8Q24.3) MUTATED | 12 | 1 | 9 | 6 | 2 | 48 |
DEL PEAK 19(8Q24.3) WILD-TYPE | 182 | 27 | 120 | 183 | 16 | 477 |
Figure S263. Get High-res Image Gene #51: 'del_8q24.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D51V7.png)
P value = 0 (logrank test), Q value = 0
Table S264. Gene #52: 'del_9p21.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 20(9P21.3) MUTATED | 587 | 409 | 0.1 - 169.8 (13.3) |
DEL PEAK 20(9P21.3) WILD-TYPE | 492 | 182 | 0.0 - 211.2 (18.7) |
Figure S264. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #1: 'Time to Death'
![](D52V1.png)
P value = 3.58e-30 (Wilcoxon-test), Q value = 5.9e-29
Table S265. Gene #52: 'del_9p21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 20(9P21.3) MUTATED | 588 | 55.6 (14.8) |
DEL PEAK 20(9P21.3) WILD-TYPE | 494 | 45.0 (14.9) |
Figure S265. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D52V2.png)
P value = 5.89e-38 (Fisher's exact test), Q value = 1.1e-36
Table S266. Gene #52: 'del_9p21.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 20(9P21.3) MUTATED | 415 | 174 |
DEL PEAK 20(9P21.3) WILD-TYPE | 156 | 338 |
Figure S266. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D52V3.png)
P value = 4.11e-10 (Fisher's exact test), Q value = 3e-09
Table S267. Gene #52: 'del_9p21.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 20(9P21.3) MUTATED | 96 | 458 |
DEL PEAK 20(9P21.3) WILD-TYPE | 162 | 309 |
Figure S267. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D52V5.png)
P value = 4.66e-13 (Wilcoxon-test), Q value = 4.4e-12
Table S268. Gene #52: 'del_9p21.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 20(9P21.3) MUTATED | 409 | 77.9 (15.5) |
DEL PEAK 20(9P21.3) WILD-TYPE | 321 | 85.6 (12.4) |
Figure S268. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D52V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S269. Gene #52: 'del_9p21.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 20(9P21.3) MUTATED | 85 | 21 | 36 | 53 | 15 | 379 |
DEL PEAK 20(9P21.3) WILD-TYPE | 109 | 7 | 93 | 136 | 3 | 146 |
Figure S269. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D52V7.png)
P value = 0.015 (Fisher's exact test), Q value = 0.035
Table S270. Gene #52: 'del_9p21.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 20(9P21.3) MUTATED | 0 | 12 | 50 | 508 |
DEL PEAK 20(9P21.3) WILD-TYPE | 1 | 9 | 21 | 449 |
Figure S270. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #8: 'RACE'
![](D52V8.png)
P value = 0.0636 (Fisher's exact test), Q value = 0.12
Table S271. Gene #52: 'del_9p21.3' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 20(9P21.3) MUTATED | 17 | 491 |
DEL PEAK 20(9P21.3) WILD-TYPE | 27 | 428 |
Figure S271. Get High-res Image Gene #52: 'del_9p21.3' versus Clinical Feature #9: 'ETHNICITY'
![](D52V9.png)
P value = 0 (logrank test), Q value = 0
Table S272. Gene #53: 'del_10p15.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 21(10P15.3) MUTATED | 546 | 437 | 0.1 - 134.3 (12.2) |
DEL PEAK 21(10P15.3) WILD-TYPE | 533 | 154 | 0.0 - 211.2 (21.0) |
Figure S272. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #1: 'Time to Death'
![](D53V1.png)
P value = 2.28e-71 (Wilcoxon-test), Q value = 6e-70
Table S273. Gene #53: 'del_10p15.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 21(10P15.3) MUTATED | 547 | 59.1 (12.4) |
DEL PEAK 21(10P15.3) WILD-TYPE | 535 | 42.2 (14.2) |
Figure S273. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D53V2.png)
P value = 1.4e-109 (Fisher's exact test), Q value = 5e-108
Table S274. Gene #53: 'del_10p15.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 21(10P15.3) MUTATED | 464 | 83 |
DEL PEAK 21(10P15.3) WILD-TYPE | 107 | 429 |
Figure S274. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D53V3.png)
P value = 0.0645 (Fisher's exact test), Q value = 0.12
Table S275. Gene #53: 'del_10p15.3' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 21(10P15.3) MUTATED | 213 | 334 |
DEL PEAK 21(10P15.3) WILD-TYPE | 239 | 297 |
Figure S275. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #4: 'GENDER'
![](D53V4.png)
P value = 1.12e-15 (Fisher's exact test), Q value = 1.3e-14
Table S276. Gene #53: 'del_10p15.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 21(10P15.3) MUTATED | 75 | 443 |
DEL PEAK 21(10P15.3) WILD-TYPE | 183 | 324 |
Figure S276. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D53V5.png)
P value = 6.84e-18 (Wilcoxon-test), Q value = 9.9e-17
Table S277. Gene #53: 'del_10p15.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 21(10P15.3) MUTATED | 398 | 77.4 (15.3) |
DEL PEAK 21(10P15.3) WILD-TYPE | 332 | 86.0 (12.5) |
Figure S277. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D53V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S278. Gene #53: 'del_10p15.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 21(10P15.3) MUTATED | 50 | 20 | 15 | 18 | 11 | 433 |
DEL PEAK 21(10P15.3) WILD-TYPE | 144 | 8 | 114 | 171 | 7 | 92 |
Figure S278. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D53V7.png)
P value = 0.00766 (Fisher's exact test), Q value = 0.019
Table S279. Gene #53: 'del_10p15.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 21(10P15.3) MUTATED | 1 | 9 | 48 | 468 |
DEL PEAK 21(10P15.3) WILD-TYPE | 0 | 12 | 23 | 489 |
Figure S279. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #8: 'RACE'
![](D53V8.png)
P value = 0.00501 (Fisher's exact test), Q value = 0.013
Table S280. Gene #53: 'del_10p15.3' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 21(10P15.3) MUTATED | 12 | 453 |
DEL PEAK 21(10P15.3) WILD-TYPE | 32 | 466 |
Figure S280. Get High-res Image Gene #53: 'del_10p15.3' versus Clinical Feature #9: 'ETHNICITY'
![](D53V9.png)
P value = 0 (logrank test), Q value = 0
Table S281. Gene #54: 'del_10p13' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 22(10P13) MUTATED | 546 | 439 | 0.1 - 134.3 (12.3) |
DEL PEAK 22(10P13) WILD-TYPE | 533 | 152 | 0.0 - 211.2 (21.1) |
Figure S281. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #1: 'Time to Death'
![](D54V1.png)
P value = 1.44e-71 (Wilcoxon-test), Q value = 3.9e-70
Table S282. Gene #54: 'del_10p13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 22(10P13) MUTATED | 547 | 59.1 (12.2) |
DEL PEAK 22(10P13) WILD-TYPE | 535 | 42.2 (14.4) |
Figure S282. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D54V2.png)
P value = 6.21e-111 (Fisher's exact test), Q value = 2.3e-109
Table S283. Gene #54: 'del_10p13' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 22(10P13) MUTATED | 465 | 82 |
DEL PEAK 22(10P13) WILD-TYPE | 106 | 430 |
Figure S283. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D54V3.png)
P value = 0.0265 (Fisher's exact test), Q value = 0.058
Table S284. Gene #54: 'del_10p13' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 22(10P13) MUTATED | 210 | 337 |
DEL PEAK 22(10P13) WILD-TYPE | 242 | 294 |
Figure S284. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #4: 'GENDER'
![](D54V4.png)
P value = 9.39e-17 (Fisher's exact test), Q value = 1.3e-15
Table S285. Gene #54: 'del_10p13' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 22(10P13) MUTATED | 73 | 445 |
DEL PEAK 22(10P13) WILD-TYPE | 185 | 322 |
Figure S285. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D54V5.png)
P value = 2.63e-16 (Wilcoxon-test), Q value = 3.5e-15
Table S286. Gene #54: 'del_10p13' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 22(10P13) MUTATED | 399 | 77.6 (15.3) |
DEL PEAK 22(10P13) WILD-TYPE | 331 | 85.8 (12.5) |
Figure S286. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D54V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S287. Gene #54: 'del_10p13' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 22(10P13) MUTATED | 50 | 19 | 15 | 17 | 11 | 435 |
DEL PEAK 22(10P13) WILD-TYPE | 144 | 9 | 114 | 172 | 7 | 90 |
Figure S287. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D54V7.png)
P value = 0.016 (Fisher's exact test), Q value = 0.037
Table S288. Gene #54: 'del_10p13' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 22(10P13) MUTATED | 1 | 9 | 47 | 469 |
DEL PEAK 22(10P13) WILD-TYPE | 0 | 12 | 24 | 488 |
Figure S288. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #8: 'RACE'
![](D54V8.png)
P value = 0.00501 (Fisher's exact test), Q value = 0.013
Table S289. Gene #54: 'del_10p13' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 22(10P13) MUTATED | 12 | 453 |
DEL PEAK 22(10P13) WILD-TYPE | 32 | 466 |
Figure S289. Get High-res Image Gene #54: 'del_10p13' versus Clinical Feature #9: 'ETHNICITY'
![](D54V9.png)
P value = 0 (logrank test), Q value = 0
Table S290. Gene #55: 'del_10p11.23' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 23(10P11.23) MUTATED | 551 | 443 | 0.1 - 134.3 (12.2) |
DEL PEAK 23(10P11.23) WILD-TYPE | 528 | 148 | 0.0 - 211.2 (21.4) |
Figure S290. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #1: 'Time to Death'
![](D55V1.png)
P value = 3.67e-75 (Wilcoxon-test), Q value = 1.1e-73
Table S291. Gene #55: 'del_10p11.23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 23(10P11.23) MUTATED | 552 | 59.3 (12.3) |
DEL PEAK 23(10P11.23) WILD-TYPE | 530 | 41.9 (14.1) |
Figure S291. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D55V2.png)
P value = 4.92e-114 (Fisher's exact test), Q value = 1.9e-112
Table S292. Gene #55: 'del_10p11.23' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 23(10P11.23) MUTATED | 470 | 82 |
DEL PEAK 23(10P11.23) WILD-TYPE | 101 | 430 |
Figure S292. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D55V3.png)
P value = 0.0485 (Fisher's exact test), Q value = 0.097
Table S293. Gene #55: 'del_10p11.23' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 23(10P11.23) MUTATED | 214 | 338 |
DEL PEAK 23(10P11.23) WILD-TYPE | 238 | 293 |
Figure S293. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #4: 'GENDER'
![](D55V4.png)
P value = 6.1e-16 (Fisher's exact test), Q value = 7.6e-15
Table S294. Gene #55: 'del_10p11.23' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 23(10P11.23) MUTATED | 76 | 448 |
DEL PEAK 23(10P11.23) WILD-TYPE | 182 | 319 |
Figure S294. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D55V5.png)
P value = 2.49e-19 (Wilcoxon-test), Q value = 3.8e-18
Table S295. Gene #55: 'del_10p11.23' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 23(10P11.23) MUTATED | 404 | 77.3 (15.3) |
DEL PEAK 23(10P11.23) WILD-TYPE | 326 | 86.3 (12.3) |
Figure S295. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D55V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S296. Gene #55: 'del_10p11.23' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 23(10P11.23) MUTATED | 50 | 20 | 14 | 18 | 10 | 440 |
DEL PEAK 23(10P11.23) WILD-TYPE | 144 | 8 | 115 | 171 | 8 | 85 |
Figure S296. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D55V7.png)
P value = 0.00155 (Fisher's exact test), Q value = 0.0046
Table S297. Gene #55: 'del_10p11.23' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 23(10P11.23) MUTATED | 1 | 9 | 50 | 470 |
DEL PEAK 23(10P11.23) WILD-TYPE | 0 | 12 | 21 | 487 |
Figure S297. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #8: 'RACE'
![](D55V8.png)
P value = 0.00325 (Fisher's exact test), Q value = 0.009
Table S298. Gene #55: 'del_10p11.23' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 23(10P11.23) MUTATED | 12 | 459 |
DEL PEAK 23(10P11.23) WILD-TYPE | 32 | 460 |
Figure S298. Get High-res Image Gene #55: 'del_10p11.23' versus Clinical Feature #9: 'ETHNICITY'
![](D55V9.png)
P value = 0 (logrank test), Q value = 0
Table S299. Gene #56: 'del_10q23.31' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 24(10Q23.31) MUTATED | 621 | 484 | 0.1 - 156.2 (12.6) |
DEL PEAK 24(10Q23.31) WILD-TYPE | 458 | 107 | 0.0 - 211.2 (22.9) |
Figure S299. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #1: 'Time to Death'
![](D56V1.png)
P value = 8.17e-64 (Wilcoxon-test), Q value = 2e-62
Table S300. Gene #56: 'del_10q23.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 24(10Q23.31) MUTATED | 622 | 57.6 (13.6) |
DEL PEAK 24(10Q23.31) WILD-TYPE | 460 | 41.5 (13.7) |
Figure S300. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D56V2.png)
P value = 2.51e-118 (Fisher's exact test), Q value = 1e-116
Table S301. Gene #56: 'del_10q23.31' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 24(10Q23.31) MUTATED | 508 | 114 |
DEL PEAK 24(10Q23.31) WILD-TYPE | 63 | 398 |
Figure S301. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D56V3.png)
P value = 3.55e-19 (Fisher's exact test), Q value = 5.4e-18
Table S302. Gene #56: 'del_10q23.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 24(10Q23.31) MUTATED | 87 | 504 |
DEL PEAK 24(10Q23.31) WILD-TYPE | 171 | 263 |
Figure S302. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D56V5.png)
P value = 2.2e-18 (Wilcoxon-test), Q value = 3.3e-17
Table S303. Gene #56: 'del_10q23.31' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 24(10Q23.31) MUTATED | 444 | 77.7 (15.2) |
DEL PEAK 24(10Q23.31) WILD-TYPE | 286 | 86.8 (11.9) |
Figure S303. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D56V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S304. Gene #56: 'del_10q23.31' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 24(10Q23.31) MUTATED | 68 | 23 | 19 | 27 | 13 | 472 |
DEL PEAK 24(10Q23.31) WILD-TYPE | 126 | 5 | 110 | 162 | 5 | 53 |
Figure S304. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D56V7.png)
P value = 0.00702 (Fisher's exact test), Q value = 0.018
Table S305. Gene #56: 'del_10q23.31' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 24(10Q23.31) MUTATED | 1 | 11 | 53 | 535 |
DEL PEAK 24(10Q23.31) WILD-TYPE | 0 | 10 | 18 | 422 |
Figure S305. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #8: 'RACE'
![](D56V8.png)
P value = 0.00831 (Fisher's exact test), Q value = 0.021
Table S306. Gene #56: 'del_10q23.31' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 24(10Q23.31) MUTATED | 16 | 522 |
DEL PEAK 24(10Q23.31) WILD-TYPE | 28 | 397 |
Figure S306. Get High-res Image Gene #56: 'del_10q23.31' versus Clinical Feature #9: 'ETHNICITY'
![](D56V9.png)
P value = 0 (logrank test), Q value = 0
Table S307. Gene #57: 'del_10q26.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 25(10Q26.3) MUTATED | 657 | 490 | 0.1 - 172.8 (13.3) |
DEL PEAK 25(10Q26.3) WILD-TYPE | 422 | 101 | 0.0 - 211.2 (22.2) |
Figure S307. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #1: 'Time to Death'
![](D57V1.png)
P value = 4.8e-50 (Wilcoxon-test), Q value = 1e-48
Table S308. Gene #57: 'del_10q26.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 25(10Q26.3) MUTATED | 659 | 56.4 (14.3) |
DEL PEAK 25(10Q26.3) WILD-TYPE | 423 | 42.0 (13.9) |
Figure S308. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D57V2.png)
P value = 7.75e-97 (Fisher's exact test), Q value = 2.5e-95
Table S309. Gene #57: 'del_10q26.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 25(10Q26.3) MUTATED | 509 | 150 |
DEL PEAK 25(10Q26.3) WILD-TYPE | 62 | 362 |
Figure S309. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D57V3.png)
P value = 8.23e-17 (Fisher's exact test), Q value = 1.2e-15
Table S310. Gene #57: 'del_10q26.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 25(10Q26.3) MUTATED | 101 | 528 |
DEL PEAK 25(10Q26.3) WILD-TYPE | 157 | 239 |
Figure S310. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D57V5.png)
P value = 3.22e-16 (Wilcoxon-test), Q value = 4.2e-15
Table S311. Gene #57: 'del_10q26.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 25(10Q26.3) MUTATED | 469 | 78.1 (15.4) |
DEL PEAK 25(10Q26.3) WILD-TYPE | 261 | 86.9 (11.3) |
Figure S311. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D57V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S312. Gene #57: 'del_10q26.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 25(10Q26.3) MUTATED | 81 | 23 | 32 | 37 | 14 | 472 |
DEL PEAK 25(10Q26.3) WILD-TYPE | 113 | 5 | 97 | 152 | 4 | 53 |
Figure S312. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D57V7.png)
P value = 0.00837 (Fisher's exact test), Q value = 0.021
Table S313. Gene #57: 'del_10q26.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 25(10Q26.3) MUTATED | 1 | 11 | 55 | 570 |
DEL PEAK 25(10Q26.3) WILD-TYPE | 0 | 10 | 16 | 387 |
Figure S313. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #8: 'RACE'
![](D57V8.png)
P value = 0.0271 (Fisher's exact test), Q value = 0.059
Table S314. Gene #57: 'del_10q26.3' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 25(10Q26.3) MUTATED | 19 | 556 |
DEL PEAK 25(10Q26.3) WILD-TYPE | 25 | 363 |
Figure S314. Get High-res Image Gene #57: 'del_10q26.3' versus Clinical Feature #9: 'ETHNICITY'
![](D57V9.png)
P value = 0.000747 (Wilcoxon-test), Q value = 0.0023
Table S315. Gene #58: 'del_11p15.5' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 26(11P15.5) MUTATED | 234 | 47.8 (15.9) |
DEL PEAK 26(11P15.5) WILD-TYPE | 848 | 51.6 (15.7) |
Figure S315. Get High-res Image Gene #58: 'del_11p15.5' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D58V2.png)
P value = 0.0515 (Fisher's exact test), Q value = 0.1
Table S316. Gene #58: 'del_11p15.5' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 26(11P15.5) MUTATED | 111 | 123 |
DEL PEAK 26(11P15.5) WILD-TYPE | 341 | 508 |
Figure S316. Get High-res Image Gene #58: 'del_11p15.5' versus Clinical Feature #4: 'GENDER'
![](D58V4.png)
P value = 0.0146 (Fisher's exact test), Q value = 0.034
Table S317. Gene #58: 'del_11p15.5' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 26(11P15.5) MUTATED | 42 | 180 |
DEL PEAK 26(11P15.5) WILD-TYPE | 216 | 587 |
Figure S317. Get High-res Image Gene #58: 'del_11p15.5' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D58V5.png)
P value = 3e-05 (Fisher's exact test), Q value = 0.00011
Table S318. Gene #58: 'del_11p15.5' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 26(11P15.5) MUTATED | 58 | 6 | 29 | 18 | 6 | 117 |
DEL PEAK 26(11P15.5) WILD-TYPE | 136 | 22 | 100 | 171 | 12 | 408 |
Figure S318. Get High-res Image Gene #58: 'del_11p15.5' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D58V7.png)
P value = 0.0903 (logrank test), Q value = 0.16
Table S319. Gene #59: 'del_11p15.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 27(11P15.1) MUTATED | 175 | 112 | 0.2 - 156.2 (16.5) |
DEL PEAK 27(11P15.1) WILD-TYPE | 904 | 479 | 0.0 - 211.2 (15.4) |
Figure S319. Get High-res Image Gene #59: 'del_11p15.1' versus Clinical Feature #1: 'Time to Death'
![](D59V1.png)
P value = 0.0697 (Fisher's exact test), Q value = 0.13
Table S320. Gene #59: 'del_11p15.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 27(11P15.1) MUTATED | 104 | 72 |
DEL PEAK 27(11P15.1) WILD-TYPE | 467 | 440 |
Figure S320. Get High-res Image Gene #59: 'del_11p15.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D59V3.png)
P value = 0.0372 (Fisher's exact test), Q value = 0.077
Table S321. Gene #59: 'del_11p15.1' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 27(11P15.1) MUTATED | 86 | 90 |
DEL PEAK 27(11P15.1) WILD-TYPE | 366 | 541 |
Figure S321. Get High-res Image Gene #59: 'del_11p15.1' versus Clinical Feature #4: 'GENDER'
![](D59V4.png)
P value = 0.0243 (Fisher's exact test), Q value = 0.054
Table S322. Gene #59: 'del_11p15.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 27(11P15.1) MUTATED | 30 | 136 |
DEL PEAK 27(11P15.1) WILD-TYPE | 228 | 631 |
Figure S322. Get High-res Image Gene #59: 'del_11p15.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D59V5.png)
P value = 0.00023 (Fisher's exact test), Q value = 0.00076
Table S323. Gene #59: 'del_11p15.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 27(11P15.1) MUTATED | 43 | 5 | 15 | 14 | 5 | 94 |
DEL PEAK 27(11P15.1) WILD-TYPE | 151 | 23 | 114 | 175 | 13 | 431 |
Figure S323. Get High-res Image Gene #59: 'del_11p15.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D59V7.png)
P value = 0.00283 (logrank test), Q value = 0.0081
Table S324. Gene #60: 'del_11p11.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 28(11P11.2) MUTATED | 159 | 111 | 0.2 - 117.4 (15.9) |
DEL PEAK 28(11P11.2) WILD-TYPE | 920 | 480 | 0.0 - 211.2 (15.5) |
Figure S324. Get High-res Image Gene #60: 'del_11p11.2' versus Clinical Feature #1: 'Time to Death'
![](D60V1.png)
P value = 0.000289 (Fisher's exact test), Q value = 0.00095
Table S325. Gene #60: 'del_11p11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 28(11P11.2) MUTATED | 105 | 54 |
DEL PEAK 28(11P11.2) WILD-TYPE | 466 | 458 |
Figure S325. Get High-res Image Gene #60: 'del_11p11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D60V3.png)
P value = 0.00293 (Fisher's exact test), Q value = 0.0083
Table S326. Gene #60: 'del_11p11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 28(11P11.2) MUTATED | 23 | 126 |
DEL PEAK 28(11P11.2) WILD-TYPE | 235 | 641 |
Figure S326. Get High-res Image Gene #60: 'del_11p11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D60V5.png)
P value = 0.00012 (Fisher's exact test), Q value = 0.00041
Table S327. Gene #60: 'del_11p11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 28(11P11.2) MUTATED | 30 | 5 | 13 | 11 | 6 | 94 |
DEL PEAK 28(11P11.2) WILD-TYPE | 164 | 23 | 116 | 178 | 12 | 431 |
Figure S327. Get High-res Image Gene #60: 'del_11p11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D60V7.png)
P value = 0.0581 (logrank test), Q value = 0.11
Table S328. Gene #61: 'del_12p13.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 29(12P13.1) MUTATED | 108 | 68 | 0.1 - 95.1 (15.5) |
DEL PEAK 29(12P13.1) WILD-TYPE | 971 | 523 | 0.0 - 211.2 (15.7) |
Figure S328. Get High-res Image Gene #61: 'del_12p13.1' versus Clinical Feature #1: 'Time to Death'
![](D61V1.png)
P value = 0.00631 (Fisher's exact test), Q value = 0.016
Table S329. Gene #61: 'del_12p13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 29(12P13.1) MUTATED | 71 | 38 |
DEL PEAK 29(12P13.1) WILD-TYPE | 500 | 474 |
Figure S329. Get High-res Image Gene #61: 'del_12p13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D61V3.png)
P value = 0.0114 (Fisher's exact test), Q value = 0.027
Table S330. Gene #61: 'del_12p13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 29(12P13.1) MUTATED | 20 | 1 | 9 | 9 | 1 | 69 |
DEL PEAK 29(12P13.1) WILD-TYPE | 174 | 27 | 120 | 180 | 17 | 456 |
Figure S330. Get High-res Image Gene #61: 'del_12p13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D61V7.png)
P value = 0.115 (Fisher's exact test), Q value = 0.2
Table S331. Gene #61: 'del_12p13.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 29(12P13.1) MUTATED | 1 | 94 |
DEL PEAK 29(12P13.1) WILD-TYPE | 43 | 825 |
Figure S331. Get High-res Image Gene #61: 'del_12p13.1' versus Clinical Feature #9: 'ETHNICITY'
![](D61V9.png)
P value = 0.00116 (Fisher's exact test), Q value = 0.0036
Table S332. Gene #62: 'del_12q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 30(12Q12) MUTATED | 42 | 3 | 16 | 12 | 2 | 71 |
DEL PEAK 30(12Q12) WILD-TYPE | 152 | 25 | 113 | 177 | 16 | 454 |
Figure S332. Get High-res Image Gene #62: 'del_12q12' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D62V7.png)
P value = 0.00702 (Fisher's exact test), Q value = 0.018
Table S333. Gene #63: 'del_12q15' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 31(12Q15) MUTATED | 37 | 4 | 14 | 12 | 3 | 71 |
DEL PEAK 31(12Q15) WILD-TYPE | 157 | 24 | 115 | 177 | 15 | 454 |
Figure S333. Get High-res Image Gene #63: 'del_12q15' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D63V7.png)
P value = 3.31e-05 (logrank test), Q value = 0.00012
Table S334. Gene #64: 'del_13q14.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 32(13Q14.2) MUTATED | 380 | 247 | 0.1 - 211.2 (15.0) |
DEL PEAK 32(13Q14.2) WILD-TYPE | 699 | 344 | 0.0 - 182.3 (16.2) |
Figure S334. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #1: 'Time to Death'
![](D64V1.png)
P value = 0.0605 (Wilcoxon-test), Q value = 0.12
Table S335. Gene #64: 'del_13q14.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 32(13Q14.2) MUTATED | 381 | 52.0 (16.2) |
DEL PEAK 32(13Q14.2) WILD-TYPE | 701 | 50.1 (15.5) |
Figure S335. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D64V2.png)
P value = 1.23e-06 (Fisher's exact test), Q value = 6.7e-06
Table S336. Gene #64: 'del_13q14.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 32(13Q14.2) MUTATED | 239 | 142 |
DEL PEAK 32(13Q14.2) WILD-TYPE | 332 | 370 |
Figure S336. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D64V3.png)
P value = 0.122 (Fisher's exact test), Q value = 0.21
Table S337. Gene #64: 'del_13q14.2' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 32(13Q14.2) MUTATED | 147 | 234 |
DEL PEAK 32(13Q14.2) WILD-TYPE | 305 | 397 |
Figure S337. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #4: 'GENDER'
![](D64V4.png)
P value = 0.00263 (Fisher's exact test), Q value = 0.0076
Table S338. Gene #64: 'del_13q14.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 32(13Q14.2) MUTATED | 72 | 294 |
DEL PEAK 32(13Q14.2) WILD-TYPE | 186 | 473 |
Figure S338. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D64V5.png)
P value = 0.00468 (Wilcoxon-test), Q value = 0.013
Table S339. Gene #64: 'del_13q14.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 32(13Q14.2) MUTATED | 269 | 79.4 (14.7) |
DEL PEAK 32(13Q14.2) WILD-TYPE | 461 | 82.4 (14.6) |
Figure S339. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D64V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S340. Gene #64: 'del_13q14.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 32(13Q14.2) MUTATED | 63 | 9 | 36 | 43 | 6 | 224 |
DEL PEAK 32(13Q14.2) WILD-TYPE | 131 | 19 | 93 | 146 | 12 | 301 |
Figure S340. Get High-res Image Gene #64: 'del_13q14.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D64V7.png)
P value = 1.74e-05 (logrank test), Q value = 6.6e-05
Table S341. Gene #65: 'del_13q22.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 33(13Q22.1) MUTATED | 363 | 235 | 0.1 - 211.2 (15.0) |
DEL PEAK 33(13Q22.1) WILD-TYPE | 716 | 356 | 0.0 - 182.3 (16.2) |
Figure S341. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #1: 'Time to Death'
![](D65V1.png)
P value = 0.013 (Wilcoxon-test), Q value = 0.031
Table S342. Gene #65: 'del_13q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 33(13Q22.1) MUTATED | 364 | 52.4 (15.5) |
DEL PEAK 33(13Q22.1) WILD-TYPE | 718 | 49.9 (15.8) |
Figure S342. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D65V2.png)
P value = 6.34e-06 (Fisher's exact test), Q value = 3.2e-05
Table S343. Gene #65: 'del_13q22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 33(13Q22.1) MUTATED | 227 | 137 |
DEL PEAK 33(13Q22.1) WILD-TYPE | 344 | 375 |
Figure S343. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D65V3.png)
P value = 0.0151 (Fisher's exact test), Q value = 0.035
Table S344. Gene #65: 'del_13q22.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 33(13Q22.1) MUTATED | 72 | 279 |
DEL PEAK 33(13Q22.1) WILD-TYPE | 186 | 488 |
Figure S344. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D65V5.png)
P value = 0.00209 (Wilcoxon-test), Q value = 0.0061
Table S345. Gene #65: 'del_13q22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 33(13Q22.1) MUTATED | 255 | 79.2 (14.6) |
DEL PEAK 33(13Q22.1) WILD-TYPE | 475 | 82.4 (14.6) |
Figure S345. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D65V6.png)
P value = 1e-04 (Fisher's exact test), Q value = 0.00035
Table S346. Gene #65: 'del_13q22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 33(13Q22.1) MUTATED | 59 | 9 | 34 | 44 | 5 | 213 |
DEL PEAK 33(13Q22.1) WILD-TYPE | 135 | 19 | 95 | 145 | 13 | 312 |
Figure S346. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D65V7.png)
P value = 0.142 (Fisher's exact test), Q value = 0.24
Table S347. Gene #65: 'del_13q22.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 33(13Q22.1) MUTATED | 10 | 313 |
DEL PEAK 33(13Q22.1) WILD-TYPE | 34 | 606 |
Figure S347. Get High-res Image Gene #65: 'del_13q22.1' versus Clinical Feature #9: 'ETHNICITY'
![](D65V9.png)
P value = 1.86e-10 (logrank test), Q value = 1.4e-09
Table S348. Gene #66: 'del_14q13.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 34(14Q13.1) MUTATED | 244 | 169 | 0.1 - 130.8 (13.8) |
DEL PEAK 34(14Q13.1) WILD-TYPE | 835 | 422 | 0.0 - 211.2 (16.5) |
Figure S348. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #1: 'Time to Death'
![](D66V1.png)
P value = 1.2e-09 (Wilcoxon-test), Q value = 8.5e-09
Table S349. Gene #66: 'del_14q13.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 34(14Q13.1) MUTATED | 244 | 56.1 (14.3) |
DEL PEAK 34(14Q13.1) WILD-TYPE | 838 | 49.2 (15.9) |
Figure S349. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D66V2.png)
P value = 2.96e-12 (Fisher's exact test), Q value = 2.7e-11
Table S350. Gene #66: 'del_14q13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 34(14Q13.1) MUTATED | 176 | 68 |
DEL PEAK 34(14Q13.1) WILD-TYPE | 395 | 444 |
Figure S350. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D66V3.png)
P value = 0.0203 (Fisher's exact test), Q value = 0.046
Table S351. Gene #66: 'del_14q13.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 34(14Q13.1) MUTATED | 45 | 188 |
DEL PEAK 34(14Q13.1) WILD-TYPE | 213 | 579 |
Figure S351. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D66V5.png)
P value = 0.00597 (Wilcoxon-test), Q value = 0.016
Table S352. Gene #66: 'del_14q13.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 34(14Q13.1) MUTATED | 178 | 79.6 (13.1) |
DEL PEAK 34(14Q13.1) WILD-TYPE | 552 | 81.8 (15.1) |
Figure S352. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D66V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S353. Gene #66: 'del_14q13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 34(14Q13.1) MUTATED | 31 | 6 | 15 | 22 | 6 | 164 |
DEL PEAK 34(14Q13.1) WILD-TYPE | 163 | 22 | 114 | 167 | 12 | 361 |
Figure S353. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D66V7.png)
P value = 0.0466 (Fisher's exact test), Q value = 0.094
Table S354. Gene #66: 'del_14q13.1' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 34(14Q13.1) MUTATED | 1 | 4 | 23 | 205 |
DEL PEAK 34(14Q13.1) WILD-TYPE | 0 | 17 | 48 | 752 |
Figure S354. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #8: 'RACE'
![](D66V8.png)
P value = 0.0569 (Fisher's exact test), Q value = 0.11
Table S355. Gene #66: 'del_14q13.1' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 34(14Q13.1) MUTATED | 4 | 201 |
DEL PEAK 34(14Q13.1) WILD-TYPE | 40 | 718 |
Figure S355. Get High-res Image Gene #66: 'del_14q13.1' versus Clinical Feature #9: 'ETHNICITY'
![](D66V9.png)
P value = 0.00176 (logrank test), Q value = 0.0052
Table S356. Gene #67: 'del_14q24.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 35(14Q24.2) MUTATED | 289 | 182 | 0.1 - 130.8 (15.1) |
DEL PEAK 35(14Q24.2) WILD-TYPE | 790 | 409 | 0.0 - 211.2 (15.9) |
Figure S356. Get High-res Image Gene #67: 'del_14q24.2' versus Clinical Feature #1: 'Time to Death'
![](D67V1.png)
P value = 0.0667 (Wilcoxon-test), Q value = 0.13
Table S357. Gene #67: 'del_14q24.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 35(14Q24.2) MUTATED | 290 | 52.2 (15.7) |
DEL PEAK 35(14Q24.2) WILD-TYPE | 792 | 50.2 (15.8) |
Figure S357. Get High-res Image Gene #67: 'del_14q24.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D67V2.png)
P value = 0.0134 (Fisher's exact test), Q value = 0.031
Table S358. Gene #67: 'del_14q24.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 35(14Q24.2) MUTATED | 171 | 119 |
DEL PEAK 35(14Q24.2) WILD-TYPE | 400 | 393 |
Figure S358. Get High-res Image Gene #67: 'del_14q24.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D67V3.png)
P value = 0.0602 (Fisher's exact test), Q value = 0.12
Table S359. Gene #67: 'del_14q24.2' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 35(14Q24.2) MUTATED | 135 | 155 |
DEL PEAK 35(14Q24.2) WILD-TYPE | 317 | 476 |
Figure S359. Get High-res Image Gene #67: 'del_14q24.2' versus Clinical Feature #4: 'GENDER'
![](D67V4.png)
P value = 0.0504 (Fisher's exact test), Q value = 0.1
Table S360. Gene #67: 'del_14q24.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 35(14Q24.2) MUTATED | 52 | 5 | 28 | 39 | 7 | 159 |
DEL PEAK 35(14Q24.2) WILD-TYPE | 142 | 23 | 101 | 150 | 11 | 366 |
Figure S360. Get High-res Image Gene #67: 'del_14q24.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D67V7.png)
P value = 0.00337 (logrank test), Q value = 0.0092
Table S361. Gene #68: 'del_14q31.3' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 36(14Q31.3) MUTATED | 273 | 170 | 0.1 - 130.8 (15.3) |
DEL PEAK 36(14Q31.3) WILD-TYPE | 806 | 421 | 0.0 - 211.2 (15.8) |
Figure S361. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #1: 'Time to Death'
![](D68V1.png)
P value = 0.0713 (Wilcoxon-test), Q value = 0.13
Table S362. Gene #68: 'del_14q31.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 36(14Q31.3) MUTATED | 274 | 52.2 (15.6) |
DEL PEAK 36(14Q31.3) WILD-TYPE | 808 | 50.3 (15.8) |
Figure S362. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D68V2.png)
P value = 0.0427 (Fisher's exact test), Q value = 0.087
Table S363. Gene #68: 'del_14q31.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 36(14Q31.3) MUTATED | 159 | 115 |
DEL PEAK 36(14Q31.3) WILD-TYPE | 412 | 397 |
Figure S363. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D68V3.png)
P value = 0.0559 (Fisher's exact test), Q value = 0.11
Table S364. Gene #68: 'del_14q31.3' versus Clinical Feature #4: 'GENDER'
nPatients | FEMALE | MALE |
---|---|---|
ALL | 452 | 631 |
DEL PEAK 36(14Q31.3) MUTATED | 128 | 146 |
DEL PEAK 36(14Q31.3) WILD-TYPE | 324 | 485 |
Figure S364. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #4: 'GENDER'
![](D68V4.png)
P value = 0.0872 (Fisher's exact test), Q value = 0.16
Table S365. Gene #68: 'del_14q31.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 36(14Q31.3) MUTATED | 50 | 6 | 29 | 36 | 8 | 145 |
DEL PEAK 36(14Q31.3) WILD-TYPE | 144 | 22 | 100 | 153 | 10 | 380 |
Figure S365. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D68V7.png)
P value = 0.0921 (Fisher's exact test), Q value = 0.17
Table S366. Gene #68: 'del_14q31.3' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 36(14Q31.3) MUTATED | 1 | 6 | 24 | 234 |
DEL PEAK 36(14Q31.3) WILD-TYPE | 0 | 15 | 47 | 723 |
Figure S366. Get High-res Image Gene #68: 'del_14q31.3' versus Clinical Feature #8: 'RACE'
![](D68V8.png)
P value = 2.76e-07 (logrank test), Q value = 1.6e-06
Table S367. Gene #69: 'del_15q14' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 37(15Q14) MUTATED | 210 | 148 | 0.2 - 134.3 (14.2) |
DEL PEAK 37(15Q14) WILD-TYPE | 869 | 443 | 0.0 - 211.2 (16.2) |
Figure S367. Get High-res Image Gene #69: 'del_15q14' versus Clinical Feature #1: 'Time to Death'
![](D69V1.png)
P value = 2.63e-06 (Wilcoxon-test), Q value = 1.4e-05
Table S368. Gene #69: 'del_15q14' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 37(15Q14) MUTATED | 211 | 55.6 (16.0) |
DEL PEAK 37(15Q14) WILD-TYPE | 871 | 49.6 (15.5) |
Figure S368. Get High-res Image Gene #69: 'del_15q14' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D69V2.png)
P value = 4.08e-09 (Fisher's exact test), Q value = 2.7e-08
Table S369. Gene #69: 'del_15q14' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 37(15Q14) MUTATED | 150 | 62 |
DEL PEAK 37(15Q14) WILD-TYPE | 421 | 450 |
Figure S369. Get High-res Image Gene #69: 'del_15q14' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D69V3.png)
P value = 0.0318 (Wilcoxon-test), Q value = 0.068
Table S370. Gene #69: 'del_15q14' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 37(15Q14) MUTATED | 132 | 79.5 (13.7) |
DEL PEAK 37(15Q14) WILD-TYPE | 598 | 81.7 (14.9) |
Figure S370. Get High-res Image Gene #69: 'del_15q14' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D69V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S371. Gene #69: 'del_15q14' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 37(15Q14) MUTATED | 26 | 8 | 14 | 22 | 4 | 138 |
DEL PEAK 37(15Q14) WILD-TYPE | 168 | 20 | 115 | 167 | 14 | 387 |
Figure S371. Get High-res Image Gene #69: 'del_15q14' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D69V7.png)
P value = 1.53e-10 (logrank test), Q value = 1.2e-09
Table S372. Gene #70: 'del_16p12.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 38(16P12.2) MUTATED | 114 | 92 | 0.4 - 78.3 (14.6) |
DEL PEAK 38(16P12.2) WILD-TYPE | 965 | 499 | 0.0 - 211.2 (15.9) |
Figure S372. Get High-res Image Gene #70: 'del_16p12.2' versus Clinical Feature #1: 'Time to Death'
![](D70V1.png)
P value = 1.07e-07 (Wilcoxon-test), Q value = 6.4e-07
Table S373. Gene #70: 'del_16p12.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 38(16P12.2) MUTATED | 114 | 58.3 (14.3) |
DEL PEAK 38(16P12.2) WILD-TYPE | 968 | 49.9 (15.7) |
Figure S373. Get High-res Image Gene #70: 'del_16p12.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D70V2.png)
P value = 8.05e-11 (Fisher's exact test), Q value = 6.4e-10
Table S374. Gene #70: 'del_16p12.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 38(16P12.2) MUTATED | 92 | 22 |
DEL PEAK 38(16P12.2) WILD-TYPE | 479 | 490 |
Figure S374. Get High-res Image Gene #70: 'del_16p12.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D70V3.png)
P value = 0.0611 (Fisher's exact test), Q value = 0.12
Table S375. Gene #70: 'del_16p12.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 38(16P12.2) MUTATED | 19 | 90 |
DEL PEAK 38(16P12.2) WILD-TYPE | 239 | 677 |
Figure S375. Get High-res Image Gene #70: 'del_16p12.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D70V5.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S376. Gene #70: 'del_16p12.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 38(16P12.2) MUTATED | 14 | 3 | 3 | 5 | 1 | 88 |
DEL PEAK 38(16P12.2) WILD-TYPE | 180 | 25 | 126 | 184 | 17 | 437 |
Figure S376. Get High-res Image Gene #70: 'del_16p12.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D70V7.png)
P value = 1.29e-09 (logrank test), Q value = 9e-09
Table S377. Gene #71: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 39(16Q23.1) MUTATED | 127 | 100 | 0.1 - 127.6 (13.0) |
DEL PEAK 39(16Q23.1) WILD-TYPE | 952 | 491 | 0.0 - 211.2 (16.2) |
Figure S377. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #1: 'Time to Death'
![](D71V1.png)
P value = 5.91e-05 (Wilcoxon-test), Q value = 0.00021
Table S378. Gene #71: 'del_16q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 39(16Q23.1) MUTATED | 127 | 55.9 (14.9) |
DEL PEAK 39(16Q23.1) WILD-TYPE | 955 | 50.1 (15.8) |
Figure S378. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D71V2.png)
P value = 6.77e-10 (Fisher's exact test), Q value = 4.9e-09
Table S379. Gene #71: 'del_16q23.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 39(16Q23.1) MUTATED | 99 | 28 |
DEL PEAK 39(16Q23.1) WILD-TYPE | 472 | 484 |
Figure S379. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D71V3.png)
P value = 0.0909 (Fisher's exact test), Q value = 0.16
Table S380. Gene #71: 'del_16q23.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 39(16Q23.1) MUTATED | 22 | 96 |
DEL PEAK 39(16Q23.1) WILD-TYPE | 236 | 671 |
Figure S380. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D71V5.png)
P value = 0.0112 (Wilcoxon-test), Q value = 0.027
Table S381. Gene #71: 'del_16q23.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 39(16Q23.1) MUTATED | 88 | 77.4 (16.4) |
DEL PEAK 39(16Q23.1) WILD-TYPE | 642 | 81.8 (14.4) |
Figure S381. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D71V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S382. Gene #71: 'del_16q23.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 39(16Q23.1) MUTATED | 15 | 3 | 6 | 7 | 2 | 94 |
DEL PEAK 39(16Q23.1) WILD-TYPE | 179 | 25 | 123 | 182 | 16 | 431 |
Figure S382. Get High-res Image Gene #71: 'del_16q23.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D71V7.png)
P value = 1.88e-09 (logrank test), Q value = 1.3e-08
Table S383. Gene #72: 'del_17p13.1' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 40(17P13.1) MUTATED | 114 | 84 | 0.1 - 92.7 (11.8) |
DEL PEAK 40(17P13.1) WILD-TYPE | 965 | 507 | 0.0 - 211.2 (16.3) |
Figure S383. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #1: 'Time to Death'
![](D72V1.png)
P value = 4.99e-07 (Wilcoxon-test), Q value = 2.8e-06
Table S384. Gene #72: 'del_17p13.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 40(17P13.1) MUTATED | 114 | 57.7 (15.0) |
DEL PEAK 40(17P13.1) WILD-TYPE | 968 | 50.0 (15.7) |
Figure S384. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D72V2.png)
P value = 1.57e-13 (Fisher's exact test), Q value = 1.5e-12
Table S385. Gene #72: 'del_17p13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 40(17P13.1) MUTATED | 96 | 18 |
DEL PEAK 40(17P13.1) WILD-TYPE | 475 | 494 |
Figure S385. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D72V3.png)
P value = 0.0344 (Fisher's exact test), Q value = 0.073
Table S386. Gene #72: 'del_17p13.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 40(17P13.1) MUTATED | 18 | 90 |
DEL PEAK 40(17P13.1) WILD-TYPE | 240 | 677 |
Figure S386. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D72V5.png)
P value = 0.0134 (Wilcoxon-test), Q value = 0.031
Table S387. Gene #72: 'del_17p13.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 40(17P13.1) MUTATED | 79 | 78.4 (13.2) |
DEL PEAK 40(17P13.1) WILD-TYPE | 651 | 81.6 (14.8) |
Figure S387. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D72V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S388. Gene #72: 'del_17p13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 40(17P13.1) MUTATED | 6 | 4 | 4 | 8 | 3 | 89 |
DEL PEAK 40(17P13.1) WILD-TYPE | 188 | 24 | 125 | 181 | 15 | 436 |
Figure S388. Get High-res Image Gene #72: 'del_17p13.1' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D72V7.png)
P value = 3.78e-08 (logrank test), Q value = 2.3e-07
Table S389. Gene #73: 'del_17q11.2' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 41(17Q11.2) MUTATED | 91 | 66 | 0.1 - 92.7 (12.2) |
DEL PEAK 41(17Q11.2) WILD-TYPE | 988 | 525 | 0.0 - 211.2 (16.2) |
Figure S389. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #1: 'Time to Death'
![](D73V1.png)
P value = 0.000205 (Wilcoxon-test), Q value = 0.00068
Table S390. Gene #73: 'del_17q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 41(17Q11.2) MUTATED | 91 | 56.4 (13.5) |
DEL PEAK 41(17Q11.2) WILD-TYPE | 991 | 50.3 (15.9) |
Figure S390. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D73V2.png)
P value = 9.35e-07 (Fisher's exact test), Q value = 5.2e-06
Table S391. Gene #73: 'del_17q11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 41(17Q11.2) MUTATED | 70 | 21 |
DEL PEAK 41(17Q11.2) WILD-TYPE | 501 | 491 |
Figure S391. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D73V3.png)
P value = 0.116 (Fisher's exact test), Q value = 0.2
Table S392. Gene #73: 'del_17q11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 41(17Q11.2) MUTATED | 15 | 69 |
DEL PEAK 41(17Q11.2) WILD-TYPE | 243 | 698 |
Figure S392. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D73V5.png)
P value = 0.0111 (Wilcoxon-test), Q value = 0.027
Table S393. Gene #73: 'del_17q11.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 41(17Q11.2) MUTATED | 67 | 76.3 (17.7) |
DEL PEAK 41(17Q11.2) WILD-TYPE | 663 | 81.8 (14.3) |
Figure S393. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D73V6.png)
P value = 6e-05 (Fisher's exact test), Q value = 0.00021
Table S394. Gene #73: 'del_17q11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 41(17Q11.2) MUTATED | 11 | 3 | 4 | 6 | 2 | 65 |
DEL PEAK 41(17Q11.2) WILD-TYPE | 183 | 25 | 125 | 183 | 16 | 460 |
Figure S394. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D73V7.png)
P value = 0.0845 (Fisher's exact test), Q value = 0.16
Table S395. Gene #73: 'del_17q11.2' versus Clinical Feature #8: 'RACE'
nPatients | AMERICAN INDIAN OR ALASKA NATIVE | ASIAN | BLACK OR AFRICAN AMERICAN | WHITE |
---|---|---|---|---|
ALL | 1 | 21 | 71 | 957 |
DEL PEAK 41(17Q11.2) MUTATED | 1 | 2 | 8 | 78 |
DEL PEAK 41(17Q11.2) WILD-TYPE | 0 | 19 | 63 | 879 |
Figure S395. Get High-res Image Gene #73: 'del_17q11.2' versus Clinical Feature #8: 'RACE'
![](D73V8.png)
P value = 0.0625 (Wilcoxon-test), Q value = 0.12
Table S396. Gene #74: 'del_18q23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 42(18Q23) MUTATED | 151 | 53.0 (16.1) |
DEL PEAK 42(18Q23) WILD-TYPE | 931 | 50.4 (15.7) |
Figure S396. Get High-res Image Gene #74: 'del_18q23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D74V2.png)
P value = 0 (logrank test), Q value = 0
Table S397. Gene #75: 'del_19q13.41' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 43(19Q13.41) MUTATED | 363 | 131 | 0.0 - 182.3 (18.7) |
DEL PEAK 43(19Q13.41) WILD-TYPE | 716 | 460 | 0.1 - 211.2 (14.3) |
Figure S397. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #1: 'Time to Death'
![](D75V1.png)
P value = 4.16e-08 (Wilcoxon-test), Q value = 2.5e-07
Table S398. Gene #75: 'del_19q13.41' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 43(19Q13.41) MUTATED | 365 | 47.3 (14.6) |
DEL PEAK 43(19Q13.41) WILD-TYPE | 717 | 52.6 (16.1) |
Figure S398. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D75V2.png)
P value = 3.95e-34 (Fisher's exact test), Q value = 7e-33
Table S399. Gene #75: 'del_19q13.41' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 43(19Q13.41) MUTATED | 99 | 267 |
DEL PEAK 43(19Q13.41) WILD-TYPE | 472 | 245 |
Figure S399. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D75V3.png)
P value = 1.35e-08 (Fisher's exact test), Q value = 8.5e-08
Table S400. Gene #75: 'del_19q13.41' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 43(19Q13.41) MUTATED | 124 | 218 |
DEL PEAK 43(19Q13.41) WILD-TYPE | 134 | 549 |
Figure S400. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D75V5.png)
P value = 5.97e-05 (Wilcoxon-test), Q value = 0.00021
Table S401. Gene #75: 'del_19q13.41' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 43(19Q13.41) MUTATED | 238 | 84.3 (13.2) |
DEL PEAK 43(19Q13.41) WILD-TYPE | 492 | 79.8 (15.2) |
Figure S401. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D75V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S402. Gene #75: 'del_19q13.41' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 43(19Q13.41) MUTATED | 54 | 3 | 60 | 153 | 4 | 92 |
DEL PEAK 43(19Q13.41) WILD-TYPE | 140 | 25 | 69 | 36 | 14 | 433 |
Figure S402. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D75V7.png)
P value = 0.146 (Fisher's exact test), Q value = 0.25
Table S403. Gene #75: 'del_19q13.41' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 43(19Q13.41) MUTATED | 20 | 316 |
DEL PEAK 43(19Q13.41) WILD-TYPE | 24 | 603 |
Figure S403. Get High-res Image Gene #75: 'del_19q13.41' versus Clinical Feature #9: 'ETHNICITY'
![](D75V9.png)
P value = 0 (logrank test), Q value = 0
Table S404. Gene #76: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 44(19Q13.43) MUTATED | 351 | 116 | 0.0 - 182.3 (20.0) |
DEL PEAK 44(19Q13.43) WILD-TYPE | 728 | 475 | 0.1 - 211.2 (14.2) |
Figure S404. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #1: 'Time to Death'
![](D76V1.png)
P value = 4.72e-14 (Wilcoxon-test), Q value = 5e-13
Table S405. Gene #76: 'del_19q13.43' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 44(19Q13.43) MUTATED | 353 | 45.7 (14.5) |
DEL PEAK 44(19Q13.43) WILD-TYPE | 729 | 53.2 (15.8) |
Figure S405. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D76V2.png)
P value = 2.06e-41 (Fisher's exact test), Q value = 4.2e-40
Table S406. Gene #76: 'del_19q13.43' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 44(19Q13.43) MUTATED | 84 | 270 |
DEL PEAK 44(19Q13.43) WILD-TYPE | 487 | 242 |
Figure S406. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D76V3.png)
P value = 1.43e-09 (Fisher's exact test), Q value = 9.9e-09
Table S407. Gene #76: 'del_19q13.43' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 44(19Q13.43) MUTATED | 124 | 208 |
DEL PEAK 44(19Q13.43) WILD-TYPE | 134 | 559 |
Figure S407. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D76V5.png)
P value = 4.12e-06 (Wilcoxon-test), Q value = 2.2e-05
Table S408. Gene #76: 'del_19q13.43' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 44(19Q13.43) MUTATED | 234 | 84.7 (13.4) |
DEL PEAK 44(19Q13.43) WILD-TYPE | 496 | 79.7 (15.0) |
Figure S408. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D76V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S409. Gene #76: 'del_19q13.43' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 44(19Q13.43) MUTATED | 58 | 4 | 62 | 150 | 4 | 76 |
DEL PEAK 44(19Q13.43) WILD-TYPE | 136 | 24 | 67 | 39 | 14 | 449 |
Figure S409. Get High-res Image Gene #76: 'del_19q13.43' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D76V7.png)
P value = 1.61e-11 (logrank test), Q value = 1.4e-10
Table S410. Gene #77: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'
nPatients | nDeath | Duration Range (Median), Month | |
---|---|---|---|
ALL | 1079 | 591 | 0.0 - 211.2 (15.7) |
DEL PEAK 45(22Q13.32) MUTATED | 289 | 213 | 0.1 - 156.2 (15.1) |
DEL PEAK 45(22Q13.32) WILD-TYPE | 790 | 378 | 0.0 - 211.2 (16.0) |
Figure S410. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #1: 'Time to Death'
![](D77V1.png)
P value = 1.31e-10 (Wilcoxon-test), Q value = 1e-09
Table S411. Gene #77: 'del_22q13.32' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 45(22Q13.32) MUTATED | 289 | 55.7 (15.6) |
DEL PEAK 45(22Q13.32) WILD-TYPE | 793 | 49.0 (15.5) |
Figure S411. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D77V2.png)
P value = 1.22e-16 (Fisher's exact test), Q value = 1.7e-15
Table S412. Gene #77: 'del_22q13.32' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
nPatients | BRAIN | CENTRAL NERVOUS SYSTEM |
---|---|---|
ALL | 571 | 512 |
DEL PEAK 45(22Q13.32) MUTATED | 212 | 77 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 359 | 435 |
Figure S412. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #3: 'TUMOR_TISSUE_SITE'
![](D77V3.png)
P value = 0.000173 (Fisher's exact test), Q value = 0.00058
Table S413. Gene #77: 'del_22q13.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
nPatients | NO | YES |
---|---|---|
ALL | 258 | 767 |
DEL PEAK 45(22Q13.32) MUTATED | 46 | 228 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 212 | 539 |
Figure S413. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #5: 'RADIATION_THERAPY'
![](D77V5.png)
P value = 0.00307 (Wilcoxon-test), Q value = 0.0086
Table S414. Gene #77: 'del_22q13.32' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 45(22Q13.32) MUTATED | 205 | 79.2 (14.9) |
DEL PEAK 45(22Q13.32) WILD-TYPE | 525 | 82.1 (14.5) |
Figure S414. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D77V6.png)
P value = 1e-05 (Fisher's exact test), Q value = 3.9e-05
Table S415. Gene #77: 'del_22q13.32' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
nPatients | ASTROCYTOMA | GLIOBLASTOMA MULTIFORME (GBM) | OLIGOASTROCYTOMA | OLIGODENDROGLIOMA | TREATED PRIMARY GBM | UNTREATED PRIMARY (DE NOVO) GBM |
---|---|---|---|---|---|---|
ALL | 194 | 28 | 129 | 189 | 18 | 525 |
DEL PEAK 45(22Q13.32) MUTATED | 43 | 10 | 16 | 18 | 6 | 196 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 151 | 18 | 113 | 171 | 12 | 329 |
Figure S415. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #7: 'HISTOLOGICAL_TYPE'
![](D77V7.png)
P value = 0.117 (Fisher's exact test), Q value = 0.2
Table S416. Gene #77: 'del_22q13.32' versus Clinical Feature #9: 'ETHNICITY'
nPatients | HISPANIC OR LATINO | NOT HISPANIC OR LATINO |
---|---|---|
ALL | 44 | 919 |
DEL PEAK 45(22Q13.32) MUTATED | 7 | 247 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 37 | 672 |
Figure S416. Get High-res Image Gene #77: 'del_22q13.32' versus Clinical Feature #9: 'ETHNICITY'
![](D77V9.png)
P value = 0.0388 (Wilcoxon-test), Q value = 0.08
Table S417. Gene #79: 'del_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 1082 | 50.8 (15.8) |
DEL PEAK 47(XQ21.1) MUTATED | 183 | 52.8 (15.9) |
DEL PEAK 47(XQ21.1) WILD-TYPE | 899 | 50.4 (15.7) |
Figure S417. Get High-res Image Gene #79: 'del_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'
![](D79V2.png)
P value = 0.0989 (Wilcoxon-test), Q value = 0.18
Table S418. Gene #79: 'del_xq21.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
nPatients | Mean (Std.Dev) | |
---|---|---|
ALL | 730 | 81.3 (14.7) |
DEL PEAK 47(XQ21.1) MUTATED | 128 | 78.9 (16.1) |
DEL PEAK 47(XQ21.1) WILD-TYPE | 602 | 81.8 (14.3) |
Figure S418. Get High-res Image Gene #79: 'del_xq21.1' versus Clinical Feature #6: 'KARNOFSKY_PERFORMANCE_SCORE'
![](D79V6.png)
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Copy number data file = all_lesions.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/GBMLGG-TP/19791525/transformed.cor.cli.txt
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Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/GBMLGG-TP/19775190/GBMLGG-TP.merged_data.txt
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Number of patients = 1083
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Number of significantly focal cnvs = 79
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Number of selected clinical features = 9
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Exclude genes that fewer than K tumors have mutations, K = 3
For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.
In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.