PARADIGM pathway analysis of mRNASeq expression data
Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1Q81CDN
- Overview
+ Introduction
- Summary

There were 46 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Signaling events regulated by Ret tyrosine kinase 113
Aurora B signaling 87
FOXM1 transcription factor network 64
Angiopoietin receptor Tie2-mediated signaling 63
HIF-1-alpha transcription factor network 61
Signaling events mediated by VEGFR1 and VEGFR2 60
p75(NTR)-mediated signaling 53
Plasma membrane estrogen receptor signaling 52
E-cadherin signaling events 52
Endothelins 47
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data