PARADIGM pathway analysis of mRNASeq expression data
Skin Cutaneous Melanoma (Metastatic)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1N0160T
- Overview
+ Introduction
- Summary

There were 61 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
BCR signaling pathway 139
IL4-mediated signaling events 132
TCR signaling in naïve CD8+ T cells 104
IL23-mediated signaling events 101
Nephrin/Neph1 signaling in the kidney podocyte 92
IL12-mediated signaling events 80
Caspase cascade in apoptosis 69
FAS signaling pathway (CD95) 69
E-cadherin signaling events 63
Calcineurin-regulated NFAT-dependent transcription in lymphocytes 61
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data