PARADIGM pathway analysis of mRNASeq expression data
Sarcoma (Primary solid tumor)
28 January 2016  |  analyses__2016_01_28
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2016): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1610ZRQ
- Overview
+ Introduction
- Summary

There were 41 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
FOXA2 and FOXA3 transcription factor networks 109
Nephrin/Neph1 signaling in the kidney podocyte 78
E-cadherin signaling events 67
Stabilization and expansion of the E-cadherin adherens junction 56
ErbB2/ErbB3 signaling events 52
IL4-mediated signaling events 46
EGFR-dependent Endothelin signaling events 45
Signaling events mediated by the Hedgehog family 40
Signaling mediated by p38-alpha and p38-beta 39
E-cadherin signaling in the nascent adherens junction 39
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data